CN108029885A - Pet care product and preparation method thereof - Google Patents
Pet care product and preparation method thereof Download PDFInfo
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- CN108029885A CN108029885A CN201711499244.9A CN201711499244A CN108029885A CN 108029885 A CN108029885 A CN 108029885A CN 201711499244 A CN201711499244 A CN 201711499244A CN 108029885 A CN108029885 A CN 108029885A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
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Abstract
The invention discloses a kind of pet care product and preparation method thereof, it is related to pet nutrition technical field.Pet care product include Moringa, microalgae, yeast extract and activated oligosaccharide.The present invention alleviates most of pet care product currently on the market and is acted on without disease resistance, it is impossible to improves immunity of pets well, alleviates the defects of pet stress reaction.The pet care product of the present invention pass through the coordinated between the components such as Moringa, microalgae, yeast extract and activated oligosaccharide, can activate body immune system, adjust central nervous system, reduce body to stress sensitiveness, with pet immunity of organisms is improved, strengthen the effect of anti-heat stress ability.
Description
Technical field
The present invention relates to pet nutrition technical field, in particular to a kind of pet care product and preparation method thereof.
Background technology
With developing rapidly for Chinese national economy, the continuous improvement of living standards of the people, the life of high quality into
The target pursued by the people, the concern to dog cat is more and more, and raising dog cat also becomes a kind of fashion, domestic dog cat cultivation kind
Class increases, and the sick probability of dog cat is also increasing.
Since status of the dog cat in human lives is being improved, the health of dog cat is also got growing concern for how
Dog cat immunity resist the disease is improved, ensures that body health also becomes more and more important.Grain is the healthy guarantee of dog cat, but
It is that the dog grain cat food in China is considered as more the source of nutrition and energy, effect in healthcare and external product phase
Than whole competitiveness remains unchanged not strong.
Most of pet care product currently on the market are acted on without disease resistance, or effect is weaker, therefore, with reference to China
The present situation of pet dog food, according to the physiological property of pet dog, dog cat immunity can be improved and to pet by researching and developing one kind
Health products without any side effects are particularly necessary and urgent.
In view of this, it is special to propose the present invention.
The content of the invention
It is an object of the present invention to provide a kind of pet care product, including Moringa, microalgae, yeast extract and activity
The components such as oligosaccharides, by the mutual cooperation between several components, can strengthen immunity of organisms, alleviate stress reaction.
The second object of the present invention is to provide a kind of preparation method of pet care product, raw material is mixed to prepare, and prepares
Method is simple, does not destroy drug ingedient, and it is easy to use to be made tablet, is easy to absorb.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme：
In a first aspect, the present invention provides a kind of pet care product, the pet care product include Moringa, microalgae, yeast
Extract and activated oligosaccharide.
Preferably, on the basis of technical solution provided by the invention, Moringa accounts for the mass percentage of pet care product
For 1-50%, preferably 1-30%.
Preferably, on the basis of technical solution provided by the invention, the pet care product press mass percentage bag
Include following component：Moringa 1-30%, microalgae 0.5-5%, yeast extract 0.5-5%, activated oligosaccharide 0.5-5%, supplemented by remaining
Material.
Preferably, on the basis of technical solution provided by the invention, the pet care product press mass percentage bag
Include following component：Moringa 10-30%, microalgae 1-5%, yeast extract 1-5%, activated oligosaccharide 0.5-4%, remaining is auxiliary material.
Preferably, on the basis of technical solution provided by the invention, the pet care product press mass percentage bag
Include following component：Moringa 10-30%, microalgae 2-5%, yeast extract 2-5%, activated oligosaccharide 1-3%, remaining is auxiliary material.
Preferably, on the basis of technical solution provided by the invention, the Moringa carries for Moringa crushed material and/or Moringa
Take thing.
Preferably, on the basis of technical solution provided by the invention, the microalgae include haematococcus pluvialis, spirulina,
Chlorella or one kind in Du Shi algaes or at least two.
Preferably, on the basis of technical solution provided by the invention, the activated oligosaccharide includes mannosan and/or low
Polyisomaltose.
Preferably, on the basis of technical solution provided by the invention, the auxiliary material includes adhesive, disintegrant, lubrication
One kind in agent, flavouring agent, wetting agent or diluent or at least two；
Preferably, one kind in starch, maltodextrin, sodium alginate or polyvinylpyrrolidone of adhesive or at least
Two kinds；
Preferably, the one kind of disintegrant in sodium carboxymethyl starch, sodium carboxymethylcellulose, microcrystalline cellulose or starch
Or at least two；
Preferably, the one kind or at least two of lubricant in silica, magnesium stearate, odium stearate or talcum powder
Kind；
Preferably, the one kind or at least two of flavouring agent in chicken liver meal, pork liver powder or powdered beef；
Preferably, wetting agent is selected from water, one kind of absolute ethyl alcohol or ethanol-water solution or at least two；
Preferably, the one kind or at least two of diluent in lactose, glucose or mannitol.
Preferably, a kind of typical pet care product, include following component by mass percentage：Moringa 1-30%, it is micro-
Algae 0.5-5%, yeast extract 0.5-5%, activated oligosaccharide 0.5-5%, adhesive 0.5-20%, disintegrant 0.5-10%, profit
Lubrication prescription 0.5-10%, flavouring agent 0.01-1%, remaining is diluent；
Preferably, the pet care product include following component by mass percentage：Moringa 10-30%, microalgae 1-
5%, yeast extract 1-5%, activated oligosaccharide 0.5-4%, adhesive 1-15%, disintegrant 0.5-10%, lubricant 0.5-
10%, flavouring agent 0.01-1%, remaining is diluent；
It is further preferred that the pet care product include following component by mass percentage：Moringa 10-30%, it is micro-
Algae 2-5%, yeast extract 2-5%, activated oligosaccharide 1-3%, adhesive 5-15%, disintegrant 1-10%, lubricant 1-10%,
Flavouring agent 0.01-1%, remaining is diluent.
Second aspect, the present invention provides a kind of preparation method of above-mentioned pet care product, by the Moringa of formula ratio, micro-
Algae, yeast extract, activated oligosaccharide and optional auxiliary material are uniformly mixed, and pet care product are made.
Further, on the basis of technical solution of the present invention, the preparation method of pet care product, comprises the following steps：
By moringa powder, microalgae, yeast extract, activated oligosaccharide and adhesive, disintegrant, diluent after mixing, add
Enter wetting agent softwood, through wet granular processed, drying, obtain dry particl, dry particl after flavouring agent and mix lubricant with being pressed
Piece, obtains tablet；
Preferably, the piece weight of tablet is 0.55-0.65g；
Preferably, tableting pressure 5-7kg.
Compared with the prior art, the present invention has the advantages that：
(1) pet care product provided by the invention are mainly by the Moringa of certain formula ratio, microalgae, yeast extract and activity
Oligosaccharides is made, and by the coordinated between each component, fragrant odour, palatability are good, by activating body immune system, promotes spleen
Cell produces antibody, strengthens the effect of T cell, stimulates the generation of vivo immunization globulin；Central nervous system is adjusted, reduces machine
Body to stress sensitiveness, improve the adaptability to environment, have and improve pet immunity of organisms, enhancing anti-heat stress ability
Effect.
(2) preparation process of pet care product provided by the invention is simple, easy to operate, can save substantial amounts of manpower thing
Power, can be suitable for industrialized production.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific
Condition person, the condition suggested according to normal condition or manufacturer carry out.Reagents or instruments used without specified manufacturer, is
The conventional products that can be obtained by commercially available purchase.
According to the first aspect of the invention, there is provided a kind of pet care product, including Moringa, microalgae, yeast extract
And activated oligosaccharide.
Preferably, the mass percentage that Moringa accounts for pet care product is 1-50%, preferably 1-30%.
Preferably, pet care product include following component by mass percentage：Moringa 1-30%, microalgae 0.5-5%, ferment
Female extract 0.5-5%, activated oligosaccharide 0.5-5%, remaining is auxiliary material.
[Moringa]
Moringa is also known as drumstick tree, is perennial tropical deciduous tree, originates in north India, and the whole world there are about 14 kinds,
Also there are a large amount of plantations in present China.Moringa is most nutritious tree in the world, it include about 20 kinds of amino acid, 46 kinds it is anti-oxidant
Agent, anti-inflammatory compound, rich in abundant trace elements K, manganese, chromium, and arginine, lysine, leucine, phenylalanine etc.,
Vitamin A, vitamin B, B1, B2, B3, B6, vitamin C (ascorbic acid), vitamin E and macroscopical mineral matter, micro member are provided
Element, there is provided good protein and dietary fiber, calcareous contained by leaf of Moringa are 4 times of milk, and protein is 2 times of milk, potassium
It is 3 times of banana, iron is 3 times of spinach, and vitamin C is 7 times of citrus, and vitamin A (bata-carotene) is 4 times of carrot, dimension
Raw element E is spirulina and 70 times of analysis for soybean powder and 40 times respectively.
The present invention is not construed as limiting the source of Moringa, can be from positions such as the leaf of Moringa oleifera, root, stem, flower, seeds.
Typical Moringa is Moringa crushed material and/or Moringa extract.
Moringa crushed material is Moringa whole plants and/or the comminuted material of leaf of Moringa and/or moringa seeds.Moringa crushed material can
To be derived from Moringa oleifera in itself, such as the powder that leaf of Moringa, moringa root, Moringa flower or moringa seeds etc. directly obtain after processing.
Moringa extract is Moringa whole plants and/or moringa oleifera leaf extractive and/or Moringa seed extract.Moringa extract
Can be derived from Moringa (such as leaf of Moringa, moringa root, Moringa flower or moringa seeds) it is extracted after Moringa extract.
The typical but non-limiting mass percentage of Moringa is, for example, 1%, 2%, 3%, 4%, 5%, 6%, 7%,
8%th, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%,
23%th, 24%, 25%, 26%, 27%, 28%, 29% or 30%.
Main component of the Moringa as pet care product, there is provided the necessary nutritional ingredient of animal, activating cell, improves body
Immunity, Green Tea Extract oxidation, promotion grow up, help digest, improving mental status, lift resisting stress capability.
[microalgae]
Microalgae is a kind of, full of nutrition, photosynthetic availability high autophyte widely distributed in land, ocean, and microalgae is thin
Contain in born of the same parents：Protein, lipid, polysaccharides, beta carotene, a variety of inorganic elements (such as Cu, Fe, Se, Mn, Zn etc.) and a variety of
The nutritional ingredient and industrial chemicals of the high values such as vitamin.
Microalgae of the present invention refers to the eukaryotic microorganisms organism containing chloroplaset, and it can carry out photosynthesis or cannot
Carry out photosynthesis.Microalgae as the obligate photoautotroph of energy and may exit off solid including not energy metabolism fixed carbon source
Determine the heterotrophic organism that carbon source is individually survived, including photosynthetic obligate heterotroph cannot be carried out.Microalgae is included in cell point
Soon the unicellular microorganism (such as chlamydomonas) separated with sister cell after splitting and microorganism (for example, volvox, its for two kinds not
With the simple many cells photosynthetic microorganism of cell type).Microalgae is further included such as chlorella, class chlorella (Parachlorella)
With the cell of Du Shi algaes.
The source and state of microalgae are not construed as limiting, the life that typical microalgae is microalgae biomass, homogenizes or be micronized
Material (slurry, thin slice, powder or powder).
Biomass represents the material produced by the growth and/or breeding of microalgae cell.Biomass can contain cell and/or
Intracellular content and extracellular material.Extracellular material includes but not limited to the compound secreted by cell.
The typical but non-limiting mass percentage of microalgae is, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%,
1%th, 2%, 3%, 4% or 5%.
Microalgae plays the role of anti-curing cancers, radioresistance, antifatigue, anti-aging and enhancing immunity of organisms etc..
[yeast extract]
Yeast extract is using food yeast as primary raw material, with the common of the enzyme of yeast itself or additional food grade enzyme
Under effect, the product that is obtained after enzymolysis (can be again through separation and Extraction).
The typical but non-limiting mass percentage of yeast extract is, for example, 0.5%, 0.6%, 0.7%, 0.8%,
0.9%th, 1%, 2%, 3%, 4% or 5%.
Yeast extract is rich in the yeast cells such as amino acid, nucleotide, peptide, polypeptide, B family vitamin and trace element
Soluble component, has and provides nutriment, anti-aging, eliminates free radical, improves immunity and integrates detoxication.
[activated oligosaccharide]
Activated oligosaccharide is the compound being polymerized containing 2-10 glycosidic bond, glycosidic bond be a monose glycosides hydroxyl and
The a certain hydroxyls dehydrate of another monose is condensed what is formed.Activated oligosaccharide is difficult to be destroyed by hydrochloric acid in gastric juice, can not also be digested enzyme decomposition, sweet tea
Spend that low, heat is low, do not increase blood glucose and blood fat substantially, effectively facilitate the growth and breeding of beneficial bacteria in human body, suppress spoilage organisms
Growth.
Typical but non-limiting activated oligosaccharide is, for example, mannosan or oligoisomaltose etc..
The typical but non-limiting mass percentage of activated oligosaccharide is, for example, 0.5%, 0.6%, 0.7%, 0.8%,
0.9%th, 1%, 2%, 3%, 4% or 5%.
Micro-ecological environment in body can be improved by using activated oligosaccharide, be conducive to Bifidobacterium and other beneficial bacteriums
Propagation, producing organic acid through metabolism reduces intestinal pH, suppresses the growth of enteral salmonella and spoilage organisms, adjusts stomach and intestine work(
Can, suppress enteral corrupt substance, change stool, it is anti-to treat constipation, and increase vitamin synthesis, improve body's immunity.
Pharmaceutically acceptable auxiliary material may be selected in auxiliary material.
Auxiliary material is added during making, health products can be fabricated to different dosage forms, increases the consumption and palatability of health products.
" pet care product include ", it is intended that it can also include other components in addition to the component, these other
Component assigns the pet care product different characteristics.In addition, " comprising " of the present invention, may be replaced by closing
" for " of formula or " by ... form ".
For example, pet care product can also including tea polyphenols etc. other components.
It should be noted that remaining is auxiliary material, refer to removed in the component of pet care product Moringa, microalgae, yeast extract,
Surplus outside activated oligosaccharide and optionally other components is auxiliary material, and auxiliary material and Moringa, microalgae, yeast extract, activity are few
Sugar and optionally the sum of mass percentage of other components are 100%.
The pet care product of the present invention using Moringa as main component, coordinate the microalgae of certain content, yeast extract and
Activated oligosaccharide is made, and obtained health products feeding is convenient, palatability is good.Pet care product are matched somebody with somebody by the collaboration between each component
Close, pet immunity of organisms can be strengthened, alleviate stress reaction caused by various situations.Experiment shows that the health products are by swashing
Body immune system living, promotes splenocyte to produce antibody, strengthens the effect of T cell, stimulates the generation of vivo immunization globulin；Adjust
Save central nervous system, reduce body to stress sensitiveness, improve the adaptability to environment, have improve dog cat immunity of organism
Power, strengthens the effect of anti-heat stress ability.
In a preferred embodiment, pet care product include following component by mass percentage：Moringa 10-
30%, microalgae 1-5%, yeast extract 1-5%, activated oligosaccharide 0.5-4%, remaining is auxiliary material.
In a preferred embodiment, pet care product include following component by mass percentage：Moringa 10-
30%, microalgae 2-5%, yeast extract 2-5%, activated oligosaccharide 1-3%, remaining is auxiliary material.
By the proportioning between preferred each component, the health-care effect of pet care product can be further enhanced, lifts pet
Immunity of organisms.
In a preferred embodiment, Moringa is Moringa crushed material and/or Moringa extract.
Preferably, Moringa is Moringa extract.Such as Moringa Ultramicro-powder.
Select Moringa extract preferably to play the effect of Moringa, be fully extracted the active ingredient of Moringa, more
Be conducive to animal body to absorb and obtain preferably health-care effect.
In a preferred embodiment, microalgae includes one in haematococcus pluvialis, spirulina, chlorella or Du Shi algaes
Kind or at least two.
Preferably, microalgae is haematococcus pluvialis, more preferably haematococcus pluvialis extract.
Haematococcus pluvialis are also known as lake life haematococcus or lake green blood ball algae, are a kind of green algas, belong to volvocales, haematococcus section,
Be suitable for production in nature, it is nontoxic.The content of Determination of Astaxanthin in Haematococcus Pluvialis is 1.5-10%, is counted as natural shrimp
" concentrate " of blue or green element.Compared with the common microalgae such as spirulina, chlorella, haematococcus pluvialis have stronger oxidation resistance.
The extract of haematococcus pluvialis is in gorgeous red, has extremely strong pigment deposition ability, not only it is anti-oxidant, disappear
There is very strong ability in terms of except free radical, and the generation of antibody can be promoted, strengthen the immune function of animal, and can improve
Hair color, improves its ornamental value.
In a preferred embodiment, activated oligosaccharide includes mannosan and/or oligoisomaltose.
Manna oligosacchride prevents pathogen to be colonized in enteron aisle, and activating macrophage, bite neutrophil cell, assists damaged tissues as drenched
Bar histocyte accelerates to recover to produce cytokine (IL-1), promotes to include antibiotic, antimycotic, other medicines including anti-parasitic medicine
Thing is preferably played effectiveness.
Oligoisomaltose can promote Bifidobacterium in enteron aisle to breed, and suppress harmful intestinal tract bacteria and corrupt substance is formed, increase
Add vitamin content, improve immunity of organisms.
By using the activated oligosaccharide for including manna oligosacchride and oligoisomaltose, body damaged tissues can not only be assisted
Reparation, and the breeding of harmful bacteria in enteron aisle can be suppressed, promote the performance of health-care effect, improve immunity of organisms.
In a preferred embodiment, be made tablet auxiliary material include adhesive, disintegrant, lubricant, flavouring agent,
One kind in wetting agent or diluent or at least two.
Preferably, one kind in starch, maltodextrin, sodium alginate, polyvinylpyrrolidone of adhesive or at least
Two kinds.
By adding adhesive, to increase the adhesive between different material, easy to which prepared by different material piece agent etc.
Form.
Preferably, the one kind of disintegrant in sodium carboxymethyl starch, sodium carboxymethylcellulose, microcrystalline cellulose or starch
Or at least two.
By adding disintegrant, to accelerate dissolving of the health products in pet body, absorbed beneficial to pet, shorten controlling for pet
Treat the cycle.
Preferably, the one kind or at least two of lubricant in silica, magnesium stearate, odium stearate or talcum powder
Kind.
By add lubricant can play help stream, it is anti-stick and lubrication purpose.
Preferably, the one kind or at least two of flavouring agent in chicken liver meal, pork liver powder or powdered beef.
By selecting at least one of chicken liver meal, pork liver powder or powdered beef to be used as flavouring agent, to improve the agreeable to the taste of health products
Property and attractant.
Preferably, wetting agent is selected from water, one kind of absolute ethyl alcohol or ethanol-water solution or at least two.
Add wetting agent and conveniently moisten material, different material is prepared into the forms such as piece agent.
Preferably, the one kind or at least two of diluent in lactose, glucose or mannitol.
By adding diluent, increase piece weight or volume, easy to later stage tabletting.
Preferably, a kind of typical pet care product, include following component by mass percentage：Moringa 1-30%, it is micro-
Algae 0.5-5%, yeast extract 0.5-5%, activated oligosaccharide 0.5-5%, adhesive 0.5-20%, disintegrant 0.5-10%, profit
Lubrication prescription 0.5-10%, flavouring agent 0.01-1%, remaining is diluent.
Here Moringa, microalgae, yeast extract and activated oligosaccharide is identical with accordingly description above.
The typical but non-limiting mass percentage of adhesive is, for example, 0.5%, 1%, 2%, 3%, 4%, 5%,
6%th, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19% or 20%.
The typical but non-limiting mass percentage of disintegrant is, for example, 0.5%, 1%, 2%, 3%, 4%, 5%,
6%th, 7%, 8%, 9% or 10%.
The typical but non-limiting mass percentage of lubricant is, for example, 0.5%, 1%, 2%, 3%, 4%, 5%,
6%th, 7%, 8%, 9% or 10%.
The typical but non-limiting mass percentage of flavouring agent is, for example, 0.01%, 0.02%, 0.05%, 0.1%,
0.2%th, 0.3%, 0.4%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9% or 1%.
" comprising " described here, it is intended that it can also include other components in addition to the component, these other components are assigned
Give the different characteristic of the pet care product.In addition, " comprising " of the present invention, may be replaced by enclosed
" for " or " by ... form ".
It should be noted that remaining is diluent, refers to and Moringa, microalgae, yeast extraction are removed in the component of pet care product
Thing, activated oligosaccharide, adhesive, disintegrant, lubricant, flavouring agent and the surplus optionally outside other components are diluent,
Diluent and Moringa, microalgae, yeast extract, activated oligosaccharide, adhesive, disintegrant, lubricant, flavouring agent and optionally its
The sum of mass percentage of his component is 100%.
The typical pet care product product is tablet, and feeding is convenient, palatability is good, can significantly increase immunity of organism
Power, alleviates stress reaction caused by various situations.
Preferably, pet care product include following component by mass percentage：Moringa 10-30%, microalgae 1-5%, ferment
Female extract 1-5%, activated oligosaccharide 0.5-4%, adhesive 1-15%, disintegrant 0.5-10%, lubricant 0.5-10%, flavor
Agent 0.01-1%, remaining is diluent.
It is further preferred that pet care product include following component by mass percentage：Moringa 10-30%, microalgae 2-
5%, yeast extract 2-5%, activated oligosaccharide 1-3%, adhesive 5-15%, disintegrant 1-10%, lubricant 1-10%, flavor
Agent 0.01-1%, remaining is diluent.
By optimizing composition proportion, the effect of can further lifting health products and health-care effect.
According to the second aspect of the invention, there is provided a kind of preparation method of above-mentioned pet care product, by formula ratio
Moringa, microalgae, yeast extract, activated oligosaccharide and optional auxiliary material are uniformly mixed, and pet care product are made.
The preparation process of health products is simple, easy to operate, can save substantial amounts of manpower and materials, can be suitable for industrialization
Production.
Preferably, the preparation method of pet care product, comprises the following steps：
By moringa powder, microalgae, yeast extract, activated oligosaccharide and adhesive, disintegrant, diluent after mixing, add
Enter wetting agent softwood, through wet granular processed, drying, obtain dry particl, dry particl after flavouring agent and mix lubricant with being pressed
Piece, obtains tablet.
Raw material through making soft, granulation, drying, tabletting, is obtained tablet, preparation method is simple, easily operated, no by this method
Drug ingedient is destroyed, it is easy to use to be made tablet, is easy to absorb.
Preferably, the piece weight of tablet is 0.55-0.65g；
Preferably, tableting pressure 5-7kg.
The animal respiratory tract protective agents piece of suitable size can be obtained by control sheet weight and hardness (tableting pressure)
Agent.
A kind of preparation method of specific pet care product, comprises the following steps：
Supplementary material is crossed into 60-80 mesh sieves, moringa powder, microalgae, yeast extract, activated oligosaccharide and adhesive (such as are formed sediment
Powder), disintegrant, diluent after mixing, add wetting agent softwood；The dyeing softwood made is put into oscillating granulator
In wet granular processed, sieve mesh number is 20-30 mesh；The wet granular prepared is uniformly laid on and is placed in stainless steel pallet, often disk is thick
Degree is no more than 2cm, puts in heated-air circulation oven, sets 50-55 DEG C of drying temperature, material is dried, and is done per 100kg wet feeds
When the dry time is about 3-4 small, stirred when 1 is small once, moisture is controlled in 3.0-5.0%；The particle of drying is crossed into 30-40
Mesh, is allowed to be dispersed into uniform dry particl；Dry particl is poured into mixer, adds 15-20 points of flavouring agent, mix lubricant
Clock；Tabletting is carried out, piece is controlled in 0.6 ± 0.05g, hardness again：5-7kg pressure.
In order to further appreciate that the present invention, effect of the present invention is done further in detail with reference to specific embodiment and comparative example
Thin explanation.Each raw material of the present invention can pass through commercially available acquisition.
Moringa Ultramicro-powder in embodiment and comparative example is to be formed by leaf of Moringa through ultramicro grinding；Yeast extract is selected from
OXOID yeast extracts LP0021；Spirulina is the commodity of blunt top spirulina (Spirulina Platensis) domestic production,
It is broken into 10 μm of particulates；Haematococcus pluvialis (Haematococcus pluvialis) commercial goods, trade name：NatuRose,
Cyanotech companies of the U.S. produce, Hawaii, America koma islands.
Embodiment 1
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 1%, spirulina powder
5%, yeast extract 0.5%, mannosan 5%, maltodextrin 0.5%, starch 10%, silica 1 0%, powdered beef
0.01%, remaining is lactose.
Embodiment 2
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 30%, chlorella powder
0.5%, yeast extract 5%, mannosan 0.5%, sodium alginate 20%, microcrystalline cellulose 0.5%, magnesium stearate 0.5%,
Pork liver powder 1%, remaining is lactose.
Embodiment 3
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 15%, chlorella powder
3%, yeast extract 2%, mannosan 3%, polyvinylpyrrolidone 10%, sodium carboxymethylcellulose 8%, odium stearate
5%, pork liver powder 0.8%, remaining is glucose.
Embodiment 4
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 10%, spirulina powder
2%, yeast extract 3%, oligoisomaltose 4%, polyvinylpyrrolidone 5%, sodium carboxymethyl starch 3%, talcum powder
3%, chicken liver meal 0.1%, remaining is glucose.
Embodiment 5
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 20%, Dunaliella peircei powder
4%, yeast extract 4%, oligoisomaltose 3%, sodium alginate 15%, sodium carboxymethyl starch 5%, silica 4%, firmly
Fatty acid magnesium 4%, chicken liver meal 0.5%, remaining is mannitol.
Embodiment 6
A kind of pet care product, replace with haematococcus pluvialis powder, remaining component and embodiment by the spirulina powder of embodiment 1
1 is identical.
Embodiment 7
A kind of pet care product, add 0.5% oligoisomaltose on the basis of embodiment 2, remaining component with
Embodiment 2 is identical.
Embodiment 8-14
A kind of preparation method of pet care product, the component that embodiment 1-7 is respectively adopted is prepared, including following step
Suddenly：
The component of embodiment 1-7 is crossed into 60 mesh sieves, by moringa powder, microalgae, yeast extract, activated oligosaccharide and adhesive,
Disintegrant, diluent after mixing, add wetting agent softwood, the dyeing softwood made are put into oscillating granulator and is made
Wet granular, sieve mesh number are 20 mesh；The wet granular prepared is uniformly laid on and is placed in stainless steel pallet, is no more than per disc thickness
2cm, puts in heated-air circulation oven, sets 50 DEG C of drying temperature, material is dried, and is about per 100kg wet feed drying times
When 3-4 is small, stirred when 1 is small once, moisture is controlled in 3.0-5.0%；The particle of drying is crossed into 30 mesh, is allowed to be dispersed into
Even dry particl；Dry particl is poured into mixer, adds flavouring agent, mix lubricant 15 minutes, tabletting, piece controls again
0.6 ± 0.02g, hardness：5-7kg pressure.
Comparative example 1
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 15%, yeast extract
2%, mannosan 3%, polyvinylpyrrolidone 10%, sodium carboxymethylcellulose 8%, odium stearate 5%, pork liver powder 0.8%,
Remaining is glucose.
As different from Example 3, chlorella powder is free of in this comparative example health products.
Comparative example 2
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 15%, chlorella powder
3%, mannosan 3%, polyvinylpyrrolidone 10%, sodium carboxymethylcellulose 8%, odium stearate 5%, pork liver powder 0.8%,
Remaining is glucose.
As different from Example 3, yeast extract is free of in this comparative example health products.
Comparative example 3
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 15%, chlorella powder
3%, yeast extract 2%, polyvinylpyrrolidone 10%, sodium carboxymethylcellulose 8%, odium stearate 5%, pork liver powder
0.8%, remaining is glucose.
As different from Example 3, mannosan is free of in this comparative example health products.
Comparative example 4
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 15%, chlorella powder
3%, polyvinylpyrrolidone 10%, sodium carboxymethylcellulose 8%, odium stearate 5%, pork liver powder 0.8%, remaining is grape
Sugar.
As different from Example 3, yeast extract and mannosan are free of in this comparative example health products.
Comparative example 5
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 15%, polyvinyl pyrrole
Alkanone 10%, sodium carboxymethylcellulose 8%, odium stearate 5%, pork liver powder 0.8%, remaining is glucose.
As different from Example 3, chlorella powder, yeast extract and mannosan are free of in this comparative example health products.
Comparative example 6
A kind of pet care product, are made of by mass percentage following component：Moringa Ultramicro-powder 0.2%, spirulina powder
10%, yeast extract 0.1%, mannosan 0.1%, maltodextrin 0.5%, starch 10%, silica 1 0%, powdered beef
0.01%, remaining is lactose.
As different from Example 1, the Moringa Ultramicro-powder in this comparative example health products, spirulina powder, yeast extract and
The mass percentage of mannosan is not within the scope of the present invention.
Comparative example 7-12
A kind of preparation method of pet care product, the component that comparative example 1-6 is respectively adopted is prepared, including following step
Suddenly：
The component of comparative example 1-6 is crossed into 60 mesh sieves, by moringa powder, optional microalgae, optional yeast extract, optional
Activated oligosaccharide after mixing, adds wetting agent softwood, the dyeing softwood made is put with adhesive, disintegrant, diluent
Enter wet granular processed in oscillating granulator, sieve mesh number is 20 mesh；The wet granular prepared is uniformly laid on and is placed in stainless steel support
In disk, it is no more than 2cm per disc thickness, puts in heated-air circulation oven, set 50 DEG C of drying temperature, material is dried, often
When 100kg wet feed drying times are about 3-4 small, stirred when 1 is small once, moisture is controlled in 3.0-5.0%；By of drying
Grain crosses 30 mesh, is allowed to be dispersed into uniform dry particl；Dry particl is poured into mixer, adds flavouring agent, mix lubricant 15
Minute, tabletting, piece is controlled in 0.6 ± 0.02g, hardness again：5-7kg pressure.
Test example
The obtained pet care product of embodiment 8-14 and comparative example 7-12 test canine, evaluate its effect,
Specific experiment process is as follows：
(1) test material
" the match level number R-King " systems that basic dog grain is provided by Lei meter Gao animal nutritious healths Science and Technology Ltd. of Foshan City
Arrange into dog grain；Health products are tested to be provided by east Ao Long pharmaceutical Co. Ltds.
(2) experimental animal and packet
The old granny rag provided by Lei meter Gao animal nutritious healths Science and Technology Ltd. of Foshan City pet breed true field is drawn
More dogs 140, the situation such as health, weight is basically identical, the age between 8~10 years old, wherein bitch 112, public dog 28.
Divide on the basis of gender, using random fashion, be divided into test group 1-13 and control group, wherein every group of public affairs dog 2, bitch 8.
(3) trial
All experiment dogs concentrate raising by enclosed breeding management is used uniformly, and a dog one is given up, and quantitative feeding (presses weight
2% calculate scale of feeding), each feeding sooner or later daily once, the wherein basic dog grain of control group dog feeding；Test group 1 feeds basis
The pet care product 2 that dog grain+embodiment 8 obtains；Test group 2 feeds the pet care product 2 that basic dog grain+embodiment 9 obtains
Piece；Test group 3 feeds the pet care product 2 that basic dog grain+embodiment 10 obtains；Test group 4 feeds basic dog grain+embodiment
11 obtained pet care product 2；Test group 5 feeds the pet care product 2 that basic dog grain+embodiment 12 obtains；Test group 6
The pet care product 2 that the basic dog grain+embodiment 13 of feeding obtains；What test group 7 fed that basic dog grain+embodiment 14 obtains dotes on
Thing health products 2；Test group 8 feeds the pet care product 2 that basic dog grain+comparative example 7 obtains；Test group 9 feeds basic dog
The pet care product 2 that grain+comparative example 8 obtains；Test group 10 feeds the pet care product 2 that basic dog grain+comparative example 9 obtains
Piece；Test group 11 feeds the pet care product 2 that basic dog grain+comparative example 10 obtains；Test group 12 feeds basic dog grain+contrast
The pet care product 2 that example 11 obtains；Test group 13 feeds the pet care product 2 that basic dog grain+comparative example 12 obtains.Ensure
Drinking-water, periodically sweeps doghouse.Test period is 10 days, is tested in July, doghouse mean temperature is 33.7 DEG C (± 2 DEG C).
(4) collection of specimens and detection method
Blood preparation is gathered in the early morning one day after of off-test, adopts 15ml on an empty stomach using foreleg vein, wherein 10ml is used
Centrifuge 3500 leaves the heart 15 minutes, separates serum, since Serum Indexes are analyzed.In addition 5ml anticoagulant heparins are thin for T lymphs
The measure of dysuria with lower abdominal colic rate.
Using automatic clinical chemistry analyzer and kit measurement serum corticotropin (ACTH), cortisol
(COR), triiodo thryonine (T3), thyroxine (T4), the value of interleukin 2 (IL-2)；Surveyed using ELISA method
Determine the immunoglobulin G (IgG) and immunoglobulin M (IgM) in serum；Bacteriolyze is measured using bacteriolyze enzyme reagent kit (turbidimetry)
Enzyme content；Using MTT colorimetric determination T lymphocyte transformation rates.
(5) result of the test
As shown in table 1, table 2 and table 3.
Influence (μ g/ml) of the table 1 to immune indexes content in serum
Note：Letter is different between different groups represents significant difference (P ＜ 0.05), identical not notable (the P ＞ of expression difference
0.05)
Influence (%) of the table 2 to T lymphocyte transformation rates
Note：Letter is different between different groups represents significant difference (P ＜ 0.05), identical not notable (the P ＞ of expression difference
0.05)
Influence of the table 3 to resisting stress index content in serum
Note：Letter is different between different groups represents significant difference (P ＜ 0.05), identical not notable (the P ＞ of expression difference
0.05)
Immunoglobulin is that have antibody activity or the chemical constitution ball egg similar to antibody it can be seen from table 1- tables 3
In vain, it is the important immune molecule of Proliferation, Differentiation humoral immunity caused by thick liquid cell after receiving antigenic stimulus as B cell.
IgG has the effect of the various actives such as antibacterium, virus, exotoxin, promotes the phagocytosis of mononuclear macrophage；IgM, which has, to be killed
Bacterium, bacteriolyze, promote phagocytosis and agglutination, has powerful anti-infectious function.Lysozyme can effectively hydrolytic bacteria cell membrane
Peptide glycan, has the effect such as antibacterial, anti-inflammatory, antiviral.T lymphocytic cell surfaces have a variety of acceptors, the cell under the stimulation of antigen
A series of changes can occur for metabolism and form, and transformed cells quantity can reflect Immune Function, measure T lymphocytes
Responsibility.This experiment pet care product can significantly improve experiment IgG, IgM of dog, lysozyme content and improve lymph
Cell transformation rate, shows that the immunity of dog can be improved.Under stress situation, the COR concentration in dog blood significantly raises, and can cause
Immune organ injury, metabolism disorder；ACTH is a kind of hormone for promoting COR releases, stress when ACTH concentration rise, make
COR is raised in serum.This experiment health products can substantially reduce the concentration of experiment dog ACTH, COR, and immune guarantor is carried out to body
Shield.T3, T4 are by thyroid gland and its peripheral tissues' secretion, are the important substances for maintaining body metabolism, participate in nutrient in machine
Reallocation and steady-state adjustment in vivo, when its content reduces, metabolic rate decreases；IL-2 can trigger T cell largely to breed, most
Auxiliary type, suppressive and cytotoxic T cell are produced eventually.Experiment health products make the reduction of experiment dog IL-2 contents, show that body is exempted from
T cell needed for epidemic disease is reduced, and dysimmunity that stress be caused is improved.Therefore, this experiment health products, which have, improves dog machine
Body immunity, strengthens the effect of anti-heat stress ability.
Analysis is understood：For test group 6 compared with test group 1, the algae powder of use is different, it turns out that giving birth to red ball using using rain
Effect of the health products of algae powder to lifting dog immunity of organisms and anti-heat stress is stronger.Test group 7 is being tried compared with test group 2
Test on the basis of 2 components of group and add oligoisomaltose, it turns out that relatively using one using the health products of two kinds of oligosaccharides compounding
The health products of kind of oligosaccharides are more preferable to the effect for strengthening immunity of pets, lifting its resisting stress.
Test group 8 is free of chlorella powder, test group 9 is compared with test group 3, health products compared with test group 3 in health products
In be free of yeast extract, test group 10 is free of mannosan compared with test group 3 in health products, test group 11 and test group 3
Compare, yeast extract and mannosan are free of in health products, test group 12 is free of bead compared with test group 3 in health products
Algae powder, yeast extract and mannosan, the results show that the raising immunity of obtained pet care product and anti-stress effect are not
Substantially, it is seen then that health products of the present invention pass through the mutual cooperation between Moringa, algae powder, yeast extract and oligosaccharides each component, ability
Play the role of being obviously improved immunity of organisms, lifting resisting stress effect.
Test group 13 is compared with experiment 1, Moringa Ultramicro-powder, spirulina powder, yeast extract and mannosan in health products
Mass percentage not within the scope of the present invention, the improvement immunity of organisms of obtained pet care product, lifting resisting stress effect
The effect answered does not reach preferable level yet, it can be seen that, only by the mutual cooperation between each component of special ratios content,
It can just play the role of being obviously improved immunity of organisms, lifting resisting stress effect.
Although being illustrated and the invention has been described with specific embodiment, but will be appreciated that without departing substantially from the present invention's
Many other change and modification can be made in the case of spirit and scope.It is, therefore, intended that wrap in the following claims
Include all such changes and modifications belonged in the scope of the invention.
Claims (10)
1. a kind of pet care product, it is characterised in that the pet care product include Moringa, microalgae, yeast extract and activity
Oligosaccharides.
2. pet care product described in accordance with the claim 1, it is characterised in that Moringa accounts for the mass percentage of pet care product
For 1-50%, preferably 1-30%.
3. pet care product described in accordance with the claim 1, it is characterised in that the pet care product press mass percentage bag
Include following component：Moringa 1-30%, microalgae 0.5-5%, yeast extract 0.5-5%, activated oligosaccharide 0.5-5%, supplemented by remaining
Material；
Preferably, the pet care product include following component by mass percentage：Moringa 10-30%, microalgae 1-5%, ferment
Female extract 1-5%, activated oligosaccharide 0.5-4%, remaining is auxiliary material；
Preferably, the pet care product include following component by mass percentage：Moringa 10-30%, microalgae 2-5%, ferment
Female extract 2-5%, activated oligosaccharide 1-3%, remaining is auxiliary material.
4. according to claim 1-3 any one of them pet care product, it is characterised in that the Moringa is Moringa crushed material
And/or Moringa extract.
5. according to claim 1-3 any one of them pet care product, it is characterised in that the microalgae includes rain and gives birth to red ball
Algae, spirulina, chlorella or one kind in Du Shi algaes or at least two.
6. according to claim 1-3 any one of them pet care product, it is characterised in that the activated oligosaccharide gathers including sweet dew
Sugar and/or oligoisomaltose.
7. pet care product described in accordance with the claim 3, it is characterised in that the auxiliary material includes adhesive, disintegrant, lubrication
One kind in agent, flavouring agent, wetting agent or diluent or at least two；
Preferably, the one kind or at least two of adhesive in starch, maltodextrin, sodium alginate or polyvinylpyrrolidone
Kind；
Preferably, one kind in sodium carboxymethyl starch, sodium carboxymethylcellulose, microcrystalline cellulose or starch of disintegrant or extremely
It is two kinds few；
Preferably, the one kind or at least two of lubricant in silica, magnesium stearate, odium stearate or talcum powder；
Preferably, the one kind or at least two of flavouring agent in chicken liver meal, pork liver powder or powdered beef；Preferably, wetting agent selects
From one kind of water, absolute ethyl alcohol or ethanol-water solution or at least two；
Preferably, the one kind or at least two of diluent in lactose, glucose or mannitol.
8. according to claim 1-3 any one of them pet care product, it is characterised in that the pet care product press quality hundred
Content is divided to include following component：Moringa 1-30%, microalgae 0.5-5%, yeast extract 0.5-5%, activated oligosaccharide 0.5-5%,
Adhesive 0.5-20%, disintegrant 0.5-10%, lubricant 0.5-10%, flavouring agent 0.01-1%, remaining is diluent；
Preferably, the pet care product include following component by mass percentage：Moringa 10-30%, microalgae 1-5%, ferment
Female extract 1-5%, activated oligosaccharide 0.5-4%, adhesive 1-15%, disintegrant 0.5-10%, lubricant 0.5-10%, flavor
Agent 0.01-1%, remaining is diluent；
It is further preferred that the pet care product include following component by mass percentage：Moringa 10-30%, microalgae 2-
5%, yeast extract 2-5%, activated oligosaccharide 1-3%, adhesive 5-15%, disintegrant 1-10%, lubricant 1-10%, flavor
Agent 0.01-1%, remaining is diluent.
9. a kind of preparation method of claim 1-8 any one of them pet care product, it is characterised in that by the peppery of formula ratio
Wood, microalgae, yeast extract, activated oligosaccharide and optional auxiliary material are uniformly mixed, and pet care product are made.
10. according to the preparation method of the pet care product described in claim 9, it is characterised in that comprise the following steps：
By moringa powder, microalgae, yeast extract, activated oligosaccharide and adhesive, disintegrant, diluent after mixing, profit is added
Humectant softwood, through wet granular processed, drying, obtains dry particl, dry particl is obtained with carrying out tabletting after flavouring agent and mix lubricant
To tablet；
Preferably, the piece weight of tablet is 0.55-0.65g；
Preferably, tableting pressure 5-7kg.
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| CN111919975A (en) * | 2020-08-24 | 2020-11-13 | 四川水利职业技术学院 | Health product for improving dog nose wettability and preparation method thereof |
| CN113230329A (en) * | 2021-05-25 | 2021-08-10 | 深圳市前海臻宠科技有限公司 | Pet anti-stress spray and manufacturing method thereof |
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