CN108026510A - 作为用于嵌合抗原受体(car)疗法的t细胞来源的骨髓浸润淋巴细胞(mil) - Google Patents

作为用于嵌合抗原受体(car)疗法的t细胞来源的骨髓浸润淋巴细胞(mil) Download PDF

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Publication number
CN108026510A
CN108026510A CN201680051121.6A CN201680051121A CN108026510A CN 108026510 A CN108026510 A CN 108026510A CN 201680051121 A CN201680051121 A CN 201680051121A CN 108026510 A CN108026510 A CN 108026510A
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cell
mil
cells
antigen
car
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Chinese (zh)
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I.M.博雷洛
S.李
K.A.努南
D.M.帕多尔
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Johns Hopkins University
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Johns Hopkins University
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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CN201680051121.6A 2015-07-08 2016-07-08 作为用于嵌合抗原受体(car)疗法的t细胞来源的骨髓浸润淋巴细胞(mil) Pending CN108026510A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562189928P 2015-07-08 2015-07-08
US62/189928 2015-07-08
PCT/US2016/041521 WO2017008019A1 (en) 2015-07-08 2016-07-08 Marrow infiltrating lymphocytes (mils) as a source of t-cells for chimeric antigen receptor (car) therapy

Publications (1)

Publication Number Publication Date
CN108026510A true CN108026510A (zh) 2018-05-11

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CN201680051121.6A Pending CN108026510A (zh) 2015-07-08 2016-07-08 作为用于嵌合抗原受体(car)疗法的t细胞来源的骨髓浸润淋巴细胞(mil)

Country Status (12)

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US (3) US11478548B2 (https=)
EP (1) EP3320087A4 (https=)
JP (2) JP2018518978A (https=)
KR (1) KR20180039068A (https=)
CN (1) CN108026510A (https=)
AU (1) AU2016291199B2 (https=)
CA (1) CA2990694A1 (https=)
HK (2) HK1254313A1 (https=)
IL (1) IL256434B2 (https=)
MA (1) MA42902A (https=)
MX (1) MX2017017083A (https=)
WO (1) WO2017008019A1 (https=)

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CN112638428A (zh) * 2018-06-12 2021-04-09 H·李·莫菲特癌症中心和研究所公司 嵌合抗原受体肿瘤浸润淋巴细胞
CN113396215A (zh) * 2018-11-30 2021-09-14 温德弥尔治疗公司 表达嵌合抗原受体(car)的骨髓浸润淋巴细胞(mil)、其制造方法及在疗法中使用的方法

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US20190284553A1 (en) 2018-03-15 2019-09-19 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
EP3735256A4 (en) 2018-03-22 2021-10-13 Windmil Therapeutics, Inc. BONE MARROW LYMPHOCYTES SPECIFIC TO PROSTATE CANCER AND ASSOCIATED USES
WO2020004337A1 (ja) * 2018-06-27 2020-01-02 国立大学法人名古屋大学 Ｃｄ３７特異的キメラ抗原レセプター
US20210275589A1 (en) * 2018-07-13 2021-09-09 Nanjing Legend Biotech Co. Ltd. Co-receptor systems for treating infectious diseases
JP2022507113A (ja) * 2018-11-05 2022-01-18 ウィンドミル セラピューティクス インコーポレイテッド クローン性の増大した骨髄浸潤リンパ球およびそれらの使用
WO2020198031A1 (en) * 2019-03-22 2020-10-01 Windmil Therapeutics Inc. Lung cancer specific marrow infiltrating lymphocytes and uses thereof
WO2021123832A1 (en) 2019-12-20 2021-06-24 Instil Bio (Uk) Limited Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof
US20230100744A1 (en) * 2020-02-28 2023-03-30 Windmil Therapeutics, Inc. Methods for enriching marrow infiltrating lymphocytes ("mils"), compositions containing enriched mils, and methods of using enriched mils
WO2022066872A1 (en) * 2020-09-24 2022-03-31 Windmil Therapeutics, Inc. Marrow infiltrating lymphocytes (mils) expressing t cell receptors, methods of manufacturing same, and method of using in therapy
US20230372397A1 (en) * 2020-10-06 2023-11-23 Iovance Biotherapeutics, Inc. Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
WO2022076606A1 (en) * 2020-10-06 2022-04-14 Iovance Biotherapeutics, Inc. Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
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CN113396215A (zh) * 2018-11-30 2021-09-14 温德弥尔治疗公司 表达嵌合抗原受体(car)的骨髓浸润淋巴细胞(mil)、其制造方法及在疗法中使用的方法

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