CN108025088B - 溶瘤性hsv1载体及其使用方法 - Google Patents

溶瘤性hsv1载体及其使用方法 Download PDF

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CN108025088B
CN108025088B CN201680039678.8A CN201680039678A CN108025088B CN 108025088 B CN108025088 B CN 108025088B CN 201680039678 A CN201680039678 A CN 201680039678A CN 108025088 B CN108025088 B CN 108025088B
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tumor
cells
viral vector
vector
oncolytic herpes
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CN108025088A (zh
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中岛藤原浩
埃尼奥·安东尼奥·基卡
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The Brigham and Women's Hospital Inc
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    • A—HUMAN NECESSITIES
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

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CN201680039678.8A 2015-05-04 2016-05-04 溶瘤性hsv1载体及其使用方法 Active CN108025088B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562156447P 2015-05-04 2015-05-04
US62/156,447 2015-05-04
PCT/US2016/030681 WO2016179226A1 (en) 2015-05-04 2016-05-04 Oncolytic hsv1 vector and methods of use

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CN108025088A CN108025088A (zh) 2018-05-11
CN108025088B true CN108025088B (zh) 2021-08-10

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US (1) US10806761B2 (cg-RX-API-DMAC7.html)
EP (2) EP3981438A1 (cg-RX-API-DMAC7.html)
JP (1) JP6865736B2 (cg-RX-API-DMAC7.html)
KR (1) KR102705177B1 (cg-RX-API-DMAC7.html)
CN (1) CN108025088B (cg-RX-API-DMAC7.html)
AU (2) AU2016257910B2 (cg-RX-API-DMAC7.html)
CA (1) CA2988196C (cg-RX-API-DMAC7.html)
DK (1) DK3291841T3 (cg-RX-API-DMAC7.html)
ES (1) ES2903349T3 (cg-RX-API-DMAC7.html)
WO (1) WO2016179226A1 (cg-RX-API-DMAC7.html)

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CN110582574A (zh) * 2017-03-13 2019-12-17 麻省理工学院 合成启动子
KR101974169B1 (ko) 2018-08-10 2019-04-30 의료법인 성광의료재단 재조합 단순 헤르페스 바이러스 및 이의 제조방법
SG11202105422RA (en) * 2018-11-29 2021-06-29 Virogin Biotech Canada Ltd Hsv vector with reduced neurotoxicity
CA3132867A1 (en) * 2019-03-14 2020-09-17 Research Institute At Nationwide Children's Hospital Syncytial oncolytic herpes simplex mutants as potent cancer therapeutics
KR102333650B1 (ko) * 2019-11-08 2021-12-01 한국해양과학기술원 신규한 인간 상피세포성장인자 융합 단백질 및 이의 용도
US20240024392A1 (en) * 2020-12-04 2024-01-25 Immvira Co., Limited Oncolytic herpes simplex type 1 viruses for treatment of brain tumors
WO2026076297A1 (en) * 2024-10-03 2026-04-09 Candel Therapeutics, Inc. Compositions and methods for treating melanoma using an oncolytic virus

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WO2014078529A1 (en) * 2012-11-14 2014-05-22 The Brigham And Women's Hospital, Inc. Oncolytic hsv1 vectors and methods of using the same

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US8450106B2 (en) * 2007-10-17 2013-05-28 The Ohio State University Research Foundation Oncolytic virus
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AU2016257910B2 (en) 2021-06-24
CA2988196C (en) 2021-04-27
CA2988196A1 (en) 2016-11-10
EP3291841B1 (en) 2021-10-20
US20180133269A1 (en) 2018-05-17
AU2021232778B2 (en) 2024-12-19
AU2016257910A1 (en) 2017-12-21
AU2021232778A1 (en) 2021-10-14
EP3291841A1 (en) 2018-03-14
ES2903349T3 (es) 2022-04-01
KR102705177B1 (ko) 2024-09-11
KR20180037140A (ko) 2018-04-11
WO2016179226A1 (en) 2016-11-10
DK3291841T3 (da) 2022-01-10
JP2018518986A (ja) 2018-07-19
CN108025088A (zh) 2018-05-11
EP3981438A1 (en) 2022-04-13
US10806761B2 (en) 2020-10-20
EP3291841A4 (en) 2018-12-05
JP6865736B2 (ja) 2021-04-28

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