CN108014059A - A kind of skin whitening, moisturizing lotion and preparation method thereof - Google Patents

A kind of skin whitening, moisturizing lotion and preparation method thereof Download PDF

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Publication number
CN108014059A
CN108014059A CN201610973429.8A CN201610973429A CN108014059A CN 108014059 A CN108014059 A CN 108014059A CN 201610973429 A CN201610973429 A CN 201610973429A CN 108014059 A CN108014059 A CN 108014059A
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parts
skin whitening
extract
moisturizing lotion
extracts
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李红
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Wuxi Faruiya Biological Cell Science Co Ltd
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Wuxi Faruiya Biological Cell Science Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to cosmetic field, is related to a kind of skin whitening, moisturizing lotion and preparation method thereof.Specifically, lotion of the invention is made of following ingredients in parts by weight:5~8 parts of Amomum cardamomum extracts, 5~8 parts of PORIA ALBA extracts, 2~5 parts of patrima villosa extracts, 0.5~1 part of sodium hydrogensulfite, 5~8 parts of Tween 80s, 1~3 part of glycerine, 2~5 parts of cetanols, 3~8 parts of squalenes, 5~8 parts of stearic acid, 0.5~2 part of Co-Q10 and 100 parts of deionized waters.The skin whitening, moisturizing lotion of the present invention is mainly used as active ingredient using plant extracts, Amomum cardamomum extract have it is shining adopt, wake up skin and whitening function, antibacterial anti-corrosion effect is provided at the same time, PORIA ALBA extract has anti-inflammatory and immunoregulation effect, and patrima villosa extract has anti-aging and antioxidation.The lotion of the present invention is free of preservative and heavy metal, safe and non-toxic, can realize permanent whitening and moistening effect.

Description

A kind of skin whitening, moisturizing lotion and preparation method thereof
Technical field
The invention belongs to cosmetic field, is related to a kind of skin whitening, moisturizing lotion and preparation method thereof.
Background technology
Lotion is a kind of liquid frost class skin care item, because seeming pure white such as milk, is gained the name.Lotion has good Moisturizing acts on, and also has moistening effect, is particularly suitable in dry spring and autumn use., can also be in the winter if neutral skin Season uses.Spring and autumn can also isolate extraneous dry weather, prevent skin in use, in addition to skin-moistening effect Water loss is too fast, avoids that skin is dry and cracked, peeling, be when dry season is outgoing must skin care item.
Would generally add the organic matter as preservative in existing product emulsion on the market, for example, Phenoxyethanol, to hydroxyl Yl benzoic acid butyl ester, potassium sorbate, sodium salicylate etc..Although these materials can provide antisepsis for lotion, production is extended The shelf-life of product, but itself there is certain toxicity, long-time service can produce human skin irritation and cause to a certain degree Damage.In addition, usually containing the heavy metal substances such as mercury, lead in existing whitening emulsion product, long-time service can harmful to human Health.
The content of the invention
In order to overcome above-mentioned technical problem, it is an object of the invention to provide one kind to be free of organic preservative and heavy metal thing Skin whitening, moisturizing lotion of matter and preparation method thereof.
To achieve these goals, the present invention adopts the following technical scheme that:
A kind of skin whitening, moisturizing lotion, it is made of following ingredients in parts by weight:5~8 parts of Amomum cardamomum extracts, 5~8 Part PORIA ALBA extract, 2~5 parts of patrima villosa extracts, 0.5~1 part of sodium hydrogensulfite, 5~8 parts of Tween-80s, 1~3 part it is sweet Oil, 2~5 parts of cetanols, 3~8 parts of squalenes, 5~8 parts of stearic acid, 0.5~2 part of Co-Q10 and 100 parts of deionized waters.
Preferably, above-mentioned skin whitening, moisturizing lotion is made of following ingredients in parts by weight:6~7 parts of Amomum cardamomum extracts, 6~7 parts of PORIA ALBA extracts, 3~4 parts of patrima villosa extracts, 0.6~0.9 part of sodium hydrogensulfite, 6~7 parts of Tween-80s, 1.5~2.5 parts of glycerine, 3~4 parts of cetanols, 5~7 parts of squalenes, 6~7 parts of stearic acid, 0.8~1.5 part of Co-Q10 and 100 Part deionized water.
It is furthermore preferred that above-mentioned skin whitening, moisturizing lotion is made of following ingredients in parts by weight:6.5 parts of Amomum cardamomum extractions Thing, 6.5 parts of PORIA ALBA extracts, 3.5 parts of patrima villosa extracts, 0.8 part of sodium hydrogensulfite, 6.5 parts of Tween-80s, 2.0 parts it is sweet Oil, 3.5 parts of cetanols, 6.0 parts of squalenes, 6.5 parts of stearic acid, 1.2 parts of Co-Q10s and 100 parts of deionized waters.
Amomum cardamomum be Zingiber cardamom platymiscium Amomum cardamomum (Amomum cardamomum L.) dry mature fruit, midwifery In Thailand, Vietnam and other places, also there are cultivation in the provinces and regions such as China Guangdong, Guangxi, Yunnan.10~December, fruit not yet cracked in yellow green Shi Caishou, warm-natured, acrid flavour, return lung, spleen, stomach, for dampness elimination, promoting the circulation of qi, middle benefit gas, preventing or arresting vomiting.Contain a variety of volatile oil in Amomum cardamomum Component (such as 1, 8-Cineole and nopinene), can be with the promoting flow of qi and blood circulation, suitable for pachylosis caused by qi depression to blood stasis, sallow, yellowish-brown Spot, pigmentation etc..In addition, volatile oil component can effectively suppress the growth of microorganism, play the role of Antimicrobial preservative.
In above-mentioned skin whitening, moisturizing lotion, the Amomum cardamomum extract is made by laxative remedy:Amomum cardamomum is cleaned and crushed, 50~200 mesh sieves are crossed, obtain Amomum cardamomum powder;According to Amomum cardamomum powder:Water=1:8~12 weight ratio, Amomum cardamomum powder is added to In water, immersion 2~4 it is small when after, volatile oil is extracted under reflux conditions, untill the amount of volatile oil is not further added by;Place 0.5 ~2 it is small when after, separate volatile oil and water, volatile oil and use desiccant dryness, obtain Amomum cardamomum extract.
Preferably, extraction is completed by volatile oil extracting tank described in upper method.
Preferably, drier is any one in anhydrous sodium sulfate, anhydrous magnesium sulfate, anhydrous calcium chloride described in upper method Kind.
Poria cocos is the sclerotium of Polyporaceae Poria cocos category fungi Poria cocos (Poria cocos (Schw.) Wolf), and multiparasitization is in pine On the tree root of section plant Japanese red pine or masson pine, the province such as Yunnan, Anhui, Hubei, Hunan, Sichuan is distributed mainly on.7~September is excavated, White portion inside sclerotium is thinly sliced or fritter, is PORIA ALBA, mild-natured, sweet in flavor, light, the thoughts of returning home, spleen, kidney channel, are used for Li Shui, excreting dampness, invigorating the spleen, calm the nerves.Polysaccharide is mainly contained in PORIA ALBA, and (such as pachyman, one kind have β-(1 → 6) pyrans Portugal The β of grape sugar side chain-(1 → 3) glucopyranose glycan) and triterpenes (such as pachymic acid and soil be not sour) component, there is anti-inflammatory, town Bitterly, resisting stress and immunological regulation etc. act on.
In above-mentioned skin whitening, moisturizing lotion, the PORIA ALBA extract is made by laxative remedy:PORIA ALBA is cleaned and crushed, 50~200 mesh sieves are crossed, obtain poria alba powder;According to poria alba powder:Ethyl acetate=1:10~30 weight ratio, by poria alba powder It is added in ethyl acetate, is 20~30 DEG C in temperature, ultrasonic extraction 2~4 times under conditions of frequency is 20~30kHz, every time Extraction 20~40 minutes, filters after extraction, is concentrated under reduced pressure after filtrate is merged, obtain PORIA ALBA extract.
Patrima villosa is the whole herb with root of Valerianaceae Patrinia scaniosaefolia platymiscium patrima villosa (Patrinia villosa Juss.), Main product is in middle and lower reach of Yangtze River each province.Autumn harvest, cold nature, acrid flavour, hardship, return stomach, large intestine, Liver Channel, for it is clearing heat and detoxicating, disappear carbuncle Apocenosis, stasis-dispelling and pain-killing.Contain in patrima villosa with flavonoid glycoside (such as Kaempferol-O- β-D- glucopyranosides) and triterpenes A variety of active ingredients based on (such as oleanolic acid), has the function that anti-oxidant, anti-aging.
In above-mentioned skin whitening, moisturizing lotion, the patrima villosa extract is made by laxative remedy:Patrima villosa is cleaned simultaneously Crush, cross 50~200 mesh sieves, obtain patrima villosa powder;According to patrima villosa powder:Ethyl acetate=1:10~20 weight ratio, Patrima villosa powder is added in ethyl acetate, is 20~30 DEG C in temperature, frequency is ultrasonic extraction under conditions of 20~30kHz 2~4 times, 40~60 minutes every time, filter after extraction, be concentrated under reduced pressure after filtrate is merged, obtain patrima villosa extract.
Co-Q10 (ubiquinone) is a kind of fat-soluble antioxidant for being present in nature, its structure is given birth to vitamin K, dimension Plain E and plastoquinone are similar, and energy manufacture and activation are participated in human body cell, is had and is improved the immunity of the human body, strengthens antioxygen Change, slow down aging and strengthen the functions such as human activity, use it for nutrient and healthcare products and food additives extensively both at home and abroad.
A kind of preparation method of skin whitening, moisturizing lotion, it includes the following steps:First by the stearic acid of formula ratio, spermaceti Alcohol, squalene, Co-Q10 and the mixing of Amomum cardamomum extract, it is stirred and heated to 60 under the speed conditions of 100~500rpm~ 80 DEG C, 10~30 minutes are kept the temperature, obtains oil phase component;Then by the PORIA ALBA extract, patrima villosa extract, Asia of formula ratio Niter cake, Tween-80, G & W mixing, are stirred and heated to 50~70 DEG C under the speed conditions of 100~500rpm, Insulation 10~30 minutes, obtains water phase components;Finally water phase components are added in oil phase component, 1000~3000rpm's Emulsified 5~10 minutes in 50~60 DEG C under speed conditions, obtain skin whitening, moisturizing lotion.
In above-mentioned preparation method, the stirring is completed by mechanically or magnetically power agitating device.
In above-mentioned preparation method, the emulsification is completed by homogenizer.
The application method of the skin whitening, moisturizing lotion of the present invention is as follows:Position first to needing to embrocate skin whitening, moisturizing lotion (such as face, neck, hand etc.) is cleaned, then takes suitable skin whitening, moisturizing lotion to embrocate at above-mentioned position, and is accompanied by light Light beating and/or rub, to promote absorption of the skin to skin whitening, moisturizing lotion.
Compared with prior art, skin whitening, moisturizing lotion of the invention is mainly using plant extracts as active ingredient, white peas or beans Cool extract have it is shining adopt, wake up skin and whitening function, while provide antibacterial anti-corrosion effect, PORIA ALBA extract has anti-inflammatory and exempts from Epidemic disease adjustment effect, patrima villosa extract have anti-aging and antioxidation.The skin whitening, moisturizing lotion of the present invention does not contain Machine preservative and heavy metal substance, it is safe and non-toxic, it can realize permanent whitening and moistening effect.
Embodiment
Technical scheme is made below in conjunction with specific embodiment further elucidated above.The following example is only used In the explanation and illustration present invention, and should not be taken as limiting the scope of the invention.Unless otherwise indicated, institute in the following example The instrument that uses, reagent, material etc. can be obtained by routine business means.
Embodiment 1:The preparation of Amomum cardamomum extract.
Crushed after 1kg Amomum cardamomums (being purchased from Bozhou Chinese medicine trade market) are eluted with water, cross 100 mesh sieves, obtain 0.8kg Amomum cardamomum powder.Above-mentioned Amomum cardamomum powder is placed in volatile oil extracting tank and adds 8kg water, immersion 3 it is small when after, under reflux conditions Volatile oil is extracted, untill the amount of volatile oil is not further added by.Place 1 it is small when after, separate volatile oil and water, volatile oil and use nothing Aqueous sodium persulfate is dried, and obtains Amomum cardamomum extract.
Embodiment 2:The preparation of PORIA ALBA extract.
Crushed after 1kg PORIA ALBAs (being purchased from Bozhou Chinese medicine trade market) are eluted with water, cross 100 mesh sieves, obtain 0.75kg poria alba powders.Above-mentioned poria alba powder is added in 15kg ethyl acetate, extracts 3 times in 25 DEG C of ultrasounds (25kHz), often Secondary 30 minutes, the dregs of a decoction are filtered to remove after extraction, filtrate merging is placed in Rotary Evaporators and is concentrated under reduced pressure, obtains white Fu Siberian cocklebur extract.
Embodiment 3:The preparation of patrima villosa extract.
Crushed after 1kg patrima villosas (being purchased from Bozhou Chinese medicine trade market) are eluted with water, cross 100 mesh sieves, obtain 0.7kg patrima villosa powder.Above-mentioned patrima villosa powder is added in 14kg ethyl acetate, in 30 DEG C of ultrasound (20kHz) extractions 3 It is secondary, 45 minutes every time, the dregs of a decoction are filtered to remove after extraction, filtrate merging is placed in Rotary Evaporators and is concentrated under reduced pressure, is obtained To patrima villosa extract.
Embodiment 4- embodiments 8:The preparation of skin whitening, moisturizing lotion.
Skin whitening, moisturizing lotion is prepared according to the formula in table 1, its preparation process is as follows:First by stearic acid, cetanol, angle Squalene, Co-Q10 and the mixing of Amomum cardamomum extract, 65 are stirred and heated to using mechanical stirring device under 400rpm rotating speeds DEG C, 30 minutes are kept the temperature, obtains oil phase component;Then by PORIA ALBA extract, patrima villosa extract, sodium hydrogensulfite, tween- 80th, G & W mixes, and 60 DEG C are stirred and heated under 300rpm rotating speeds using mechanical stirring device, 30 minutes is kept the temperature, obtains To water phase components;Finally water phase components are added in oil phase component, are emulsified using homogenizer under 3000rpm rotating speeds in 55 DEG C 8 minutes, obtain skin whitening, moisturizing lotion.
The prescription and dosage of 1. skin whitening, moisturizing lotion of table
According to the test method in People's Republic of China's light industry standard QB/T1857-2013 moisturizing creams to above-mentioned Skin whitening, moisturizing lotion is detected, and the results are shown in Table 2 for it.As shown in Table 2, skin whitening, moisturizing lotion of the invention meets industry mark Alignment request, possesses development prospect.
The Testing index result of 2. skin whitening, moisturizing lotion of table
Experimental example 1:Skin whitening, moisturizing emulsion intercalation method investigates experiment.
In order to evaluate skin whitening, moisturizing emulsion intercalation method, respectively with the 1, 8-Cineole in Amomum cardamomum extract and β-pinane Kaempferol-O- β-D- glucopyranoses in alkene, PORIA ALBA extract pachymic acid and native not acid and patrima villosa extract Glycosides is investigated as detection material.
The lotion in 1ml embodiments 4 to 8 is measured respectively, and is diluted with deionized water and be settled to 15ml, and it is quiet in 37 DEG C Put.Then sampled at the 0th, 1,2,3,4,5,6 and 7 week, content, its result such as table 3 are measured by GC-MS methods or HPLC-MS methods It is shown.
The stability test of 3. active ingredient of table
As shown in Table 3, the content of the active material in skin whitening, moisturizing lotion of the invention over time and reduce journey Spend it is very little, by the placement of 7 weeks, 5 kinds detection materials final contents be maintained to more than 96%, show this hair Active material in bright skin whitening, moisturizing lotion has of a relatively high stability, is conducive to play lasting action effect.
Experimental example 2:The Skin Irritation Test of skin whitening, moisturizing lotion.
Skin Irritation Test is carried out using obtained skin whitening, moisturizing lotion in embodiment 4~8.It is 2.0 to choose 30 weight The rabbit of~2.5kg is randomly divided into 5 groups as experimental animal, every group 6, half male and half female.24h scissors and electricity before experiment One piece of region is respectively shaved out in dynamic shave rabbit back backbone both sides of being in, and size is about 10cm × 5cm, wherein left side coating lotion, Right side compares for self-blank.Coating 1 time daily, is used continuously 7d, and 5,10, the 30 and 60min observations after lotion is coated Skin whether there is erythema and oedema phenomenon, if there is obvious damage, takes skin to make histopathologic examination.
Skin wound repair scoring is carried out to experimental animal according to table 4, after calculating mean scores, according to table 5 into assassination Swash intensity evaluation.
4. skin wound repair of table scores
5. skin irritatin intensity evaluation of table
Intensity Score value
It is nonirritant < 0.5
Slight stimulation < 2.0
Moderate irritation < 6.0
Strong and stimulating > 6.0
6. Skin Irritation Test result of table
Test zone Embodiment 4 Embodiment 5 Embodiment 6 Embodiment 7 Embodiment 8
Tested skin region 0 0 0 0 0
Blank district 0 0 0 0 0
From the result in table 6, skin whitening, moisturizing lotion of the invention is feminine gender to the Skin Irritation Test result of rabbit, Obvious stimulation effect is not produced to family's rabbit skin.
Experimental example 3:The replenishing water and preserving moisture effect test of skin whitening, moisturizing lotion.
It is 20~40 years old women as subject to select 20 ages, is randomly divided into 5 groups, every group of 4 people.UseCM820 type moisture of skin tester (being purchased from Courage-Khazaka companies of Germany) is before lotion is embrocated, painting Wipe after ten minutes and embrocate 1 it is small when after three point in time measurement subject's forehead regions skin moisture content, working environment Temperature is 20~25 DEG C, and relative humidity is 40~50%, and moisture unit is au (arbitrary unit), its result such as table Shown in 7.
Table 7. embrocates the skin moisture content result before and after lotion
Testing time Embodiment 4 Embodiment 5 Embodiment 6 Embodiment 7 Embodiment 8
Before embrocating (au) 32.5 32.3 33.5 33.4 32.2
Embrocate (au) after ten minutes 89.5 89.6 89.7 89.8 91.2
Embrocate 1 it is small when after (au) 76.8 75.7 76.3 76.5 78.5
From the result in table 7, skin moisture content is significantly increased after embrocating lotion, and can be small at 1 When time cycle within still keep higher moisture, show that the skin whitening, moisturizing lotion of the present invention possesses excellent moisturizing and protects Wet effect.
Experimental example 4:The whitening effect experiment of skin whitening, moisturizing lotion.
It is 20~40 years old women as subject to select 30 ages, is randomly divided into 5 groups, every group of 6 people, each group is embrocated respectively Obtained skin whitening, moisturizing lotion in embodiment 4~8.Respectively before embrocating lotion and embrocate half an hour, 1 it is small when and 2 it is small when after, Score according to the data in table 8 whitening effect of lotion, calculate average mark, the results are shown in Table 9 for it.
8. whitening effect score-system of table
Moisturizing effect Score value
To no effect 0
Slight whitening effect 1
Moderate whitening effect 2
Notable whitening effect 3
Table 9. embrocates the skin whitening effects after lotion
Testing time Embodiment 4 Embodiment 5 Embodiment 6 Embodiment 7 Embodiment 8
Before embrocating (au) 0 0 0 0 0
Embrocate 0.5 it is small when after (au) 1.50 2.00 1.50 1.83 2.17
Embrocate 1 it is small when after (au) 2.00 2.33 2.25 2.25 2.66
Embrocate 2 it is small when after (au) 1.83 2.16 1.83 2.16 2.33
From the result in table 9, after embrocating lotion 30 minutes, skin lightening degree can effectively improve, and embrocate 1 It is further strengthened after hour, and certain whitening effect is able to maintain that within the time cycle when 2 is small, shows this hair Bright skin whitening, moisturizing lotion possesses excellent whitening effect.

Claims (10)

1. a kind of skin whitening, moisturizing lotion, it is made of following ingredients in parts by weight:5~8 parts of Amomum cardamomum extracts, 5~8 parts PORIA ALBA extract, 2~5 parts of patrima villosa extracts, 0.5~1 part of sodium hydrogensulfite, 5~8 parts of Tween-80s, 1~3 part it is sweet Oil, 2~5 parts of cetanols, 3~8 parts of squalenes, 5~8 parts of stearic acid, 0.5~2 part of Co-Q10 and 100 parts of deionized waters.
2. skin whitening, moisturizing lotion according to claim 1, it is characterised in that:
The skin whitening, moisturizing lotion is made of following ingredients in parts by weight:6~7 parts of Amomum cardamomum extracts, 6~7 parts of white Fu Siberian cocklebur extract, 3~4 parts of patrima villosa extracts, 0.6~0.9 part of sodium hydrogensulfite, 6~7 parts of Tween-80s, 1.5~2.5 parts it is sweet Oil, 3~4 parts of cetanols, 5~7 parts of squalenes, 6~7 parts of stearic acid, 0.8~1.5 part of Co-Q10 and 100 parts of deionized waters.
3. skin whitening, moisturizing lotion according to claim 1, it is characterised in that:
The skin whitening, moisturizing lotion is made of following ingredients in parts by weight:6.5 parts of Amomum cardamomum extracts, 6.5 parts of PORIA ALBAs Extract, 3.5 parts of patrima villosa extracts, 0.8 part of sodium hydrogensulfite, 6.5 parts of Tween-80s, 2.0 parts of glycerine, 3.5 parts of spermaceti Alcohol, 6.0 parts of squalenes, 6.5 parts of stearic acid, 1.2 parts of Co-Q10s and 100 parts of deionized waters.
4. skin whitening, moisturizing lotion according to any one of claim 1 to 3, it is characterised in that:
The Amomum cardamomum extract is made by laxative remedy:Amomum cardamomum is cleaned and crushed, crosses 50~200 mesh sieves, obtains Amomum cardamomum Powder;According to Amomum cardamomum powder:Water=1:8~12 weight ratio, Amomum cardamomum powder is added to the water, immersion 2~4 it is small when after, return Volatile oil is extracted under the conditions of stream, untill the amount of volatile oil is not further added by;Place 0.5~2 it is small when after, separate volatile oil and Water, volatile oil use desiccant dryness, obtain Amomum cardamomum extract.
5. skin whitening, moisturizing lotion according to claim 4, it is characterised in that:
The extraction is completed by volatile oil extracting tank.
6. skin whitening, moisturizing lotion according to claim 4, it is characterised in that:
Any one of the drier in anhydrous sodium sulfate, anhydrous magnesium sulfate, anhydrous calcium chloride.
7. skin whitening, moisturizing lotion according to any one of claim 1 to 3, it is characterised in that:
The PORIA ALBA extract is made by laxative remedy:PORIA ALBA is cleaned and crushed, 50~200 mesh sieves is crossed, obtains PORIA ALBA Powder;According to poria alba powder:Ethyl acetate=1:10~30 weight ratio, poria alba powder is added in ethyl acetate, in temperature For 20~30 DEG C, ultrasonic extraction 2~4 times, is extracted 20~40 minutes, extraction finishes every time under conditions of frequency is 20~30kHz After filter, be concentrated under reduced pressure after filtrate is merged, obtain PORIA ALBA extract.
8. skin whitening, moisturizing lotion according to any one of claim 1 to 3, it is characterised in that:
The patrima villosa extract is made by laxative remedy:Patrima villosa is cleaned and crushed, 50~200 mesh sieves is crossed, obtains white Flower Patrinia scaniosaefolia powder;According to patrima villosa powder:Ethyl acetate=1:10~20 weight ratio, ethyl acetate is added to by patrima villosa powder In, it is 20~30 DEG C in temperature, ultrasonic extraction 2~4 times under conditions of frequency is 20~30kHz, 40~60 minutes every time, extraction After filter, be concentrated under reduced pressure after filtrate is merged, obtain patrima villosa extract.
9. a kind of preparation method of skin whitening, moisturizing lotion according to any one of claim 1 to 8, it includes step as follows Suddenly:The stearic acid of formula ratio, cetanol, squalene, Co-Q10 and Amomum cardamomum extract are mixed first, in 100~500rpm Speed conditions under be stirred and heated to 60~80 DEG C, keep the temperature 10~30 minutes, obtain oil phase component;Then by the white of formula ratio Tuckahoe extracts, patrima villosa extract, sodium hydrogensulfite, Tween-80, G & W mixing, in the rotating speed of 100~500rpm Under the conditions of be stirred and heated to 50~70 DEG C, keep the temperature 10~30 minutes, obtain water phase components;Water phase components are finally added to oil In phase component, emulsified 5~10 minutes in 50~60 DEG C under the speed conditions of 1000~3000rpm, obtain skin whitening, moisturizing lotion.
10. preparation method according to claim 9, it is characterised in that:
The stirring is completed by mechanically or magnetically power agitating device;
The emulsification is completed by homogenizer.
CN201610973429.8A 2016-11-04 2016-11-04 A kind of skin whitening, moisturizing lotion and preparation method thereof Pending CN108014059A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108852965A (en) * 2018-08-02 2018-11-23 芜湖扬展新材料科技服务有限公司 A kind of preparation method of the Whitening, spot lotion of the extract containing Amomum cardamomum
CN111991310A (en) * 2020-08-29 2020-11-27 荣鼎(广东)生物科技有限公司 Whitening and moisturizing lotion based on nicotinamide component
CN112370389A (en) * 2020-11-18 2021-02-19 荣鼎(广东)生物科技有限公司 Stock solution of epidermal active nonapeptide
CN117860793A (en) * 2024-02-28 2024-04-12 云南白药集团中药资源有限公司 Fresh processing method of traditional Chinese medicine poria cocos in production place

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Application publication date: 20180511