CN107970303A - A kind of herbal composite that can effectively treat the black and thin disease of turbot - Google Patents
A kind of herbal composite that can effectively treat the black and thin disease of turbot Download PDFInfo
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- CN107970303A CN107970303A CN201610919306.6A CN201610919306A CN107970303A CN 107970303 A CN107970303 A CN 107970303A CN 201610919306 A CN201610919306 A CN 201610919306A CN 107970303 A CN107970303 A CN 107970303A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
Abstract
The present invention relates to a kind of herbal composite that can effectively treat the black and thin disease of turbot, it is characterised in that：Include the following components of the proportioning of fraction by weight：10~20 parts of Chinese gall, 25~35 parts of the Chinese bulbul, 45~55 parts of Cortex Phellodendri, 15~25 parts of Herba Andrographitis, 20~35 parts of Angelica sinensis, 15~25 parts of Radix Codonopsis, 12~24 parts of honeysuckle, 10~20 parts of the bark of eucommia, 8~15 parts of the bark of ash, 6~15 parts of frankincense, 2~5 parts of myrrh.The present invention is theoretical according to Chinese medicine monarch scientific compatibility, quantitative, half-quantitative detection is carried out to the active ingredient of wherein most medicinal material with modern means of science and technology, obtained finished product has good preventive and therapeutic effect to the black and thin disease of turbot, each taste medicine collaboration works, not only strengthen the inhibitory action to pathogen, and reduce the toxicity of simple, there is significant prevention effect to the black and thin disease of turbot, it is a kind of good effect, nuisanceless, noresidue, Chinese medicine easy to use, especially suitable for the extensive turbot class cultivation of batch production.
Description
Technical field
It is especially a kind of effectively to treat in the black and thin disease of turbot the invention belongs to turbot fish technical field of pharmaceuticals
Herbal-composition.
Background technology
Turbot (Scophthalmus maximus) belongs to Pleuronectiformes, Bothidae, brill category, originates in Atlantic Ocean northeast
Dwell the rare fish of seawater for portion, a kind of bottom of Coast of Europe.China was introduced from 1992, turbot aquaculture industry is grown rapidly, existing
The Representative Cultivars of the northern area of China seawater fish industrial aquaculture are become.But with the drastically expansion of cultivation scale, disease
Problem has become one of main bottleneck for restricting industry development.Wherein, nursery stage Hei Shou diseases have rapid onset, death rate height
The features such as, become one of principal element for influencing nursery stage survival rate.Its classical symptom is that sick fry body colour blacks, and fish body is thin
Weak, compared with normal fry, head is big, trunk is small, in deformity, and it is very low to suffer from black and thin sick turbot seedling distortion ratio.Due to lacking
Special-purpose medicaments are prevented, and culturist often blindly carrys out symptom management using various antibiotic, but produces little effect；It may also influence at the same time
The food-safety problem of adult fish.
In the drug therapy of common disease, Chinese herbal medicine not only has that toxic side effect is small, drug residue free and performance are more
The advantages that sample, also have and improve aquatic livestock production performance, efficiency of feed utilization, promote growth and improve non-specific immunity
And other effects.In aquaculture process, particularly in freshwater aquiculture, Chinese herbal medicine using extensive, to it is bacillary, viral, post
Natural disposition disease has corresponding formula and has good effect.Therefore, increasingly it is subject to people using herbal control fish disease
Concern.
The content of the invention
It is an object of the invention in place of overcome the deficiencies in the prior art, there is provided safe to use, environmentally protective one kind can
The effectively herbal composite of the treatment black and thin disease of turbot.
The technical solution adopted by the present invention is：
A kind of herbal composite that can effectively treat the black and thin disease of turbot, it is characterised in that：Match somebody with somebody including fraction by weight
The following components of ratio：10~20 parts of Chinese gall, 25~35 parts of the Chinese bulbul, 45~55 parts of Cortex Phellodendri, 15~25 parts of Herba Andrographitis, Angelica sinensis 20
~35 parts, 15~25 parts of Radix Codonopsis, 12~24 parts of honeysuckle.
Moreover, the component further include among the bark of eucommia, the bark of ash, frankincense, myrrh any one, it is two kinds any, any three
Kind or any four.
Moreover, the component further includes 10~20 parts of the bark of eucommia, 8~15 parts of the bark of ash, 6~15 parts of frankincense, 2~5 parts of myrrh.
Moreover, the component is 20 parts of Chinese gall, and 30 parts of the Chinese bulbul, 50 parts of Cortex Phellodendri, 20 parts of Herba Andrographitis, 25 parts of Angelica sinensis, party
20 parts of ginseng, 20 parts of honeysuckle, 10 parts of the bark of eucommia, 8 parts of the bark of ash, 6 parts of frankincense, 5 parts of of myrrh
The advantages and positive effects of the present invention are：
The present invention is theoretical according to Chinese medicine monarch scientific compatibility, with modern means of science and technology to wherein most medicinal material
Active ingredient carries out quantitative, half-quantitative detection, and obtained finished product has the black and thin disease of turbot good preventive and therapeutic effect, each taste medicine association
With working, the inhibitory action to pathogen is not only strengthened, but also reduces the toxicity of simple, is had to the black and thin disease of turbot aobvious
The prevention effect of work, is a kind of good effect, nuisanceless, noresidue, Chinese medicine easy to use, extensive especially suitable for batch production
Turbot class cultivates.
Embodiment
With reference to embodiment, the present invention is further described, and following embodiments are illustrative, be not it is limited,
Protection scope of the present invention cannot be limited with following embodiments.
A kind of herbal composite that can effectively treat the black and thin disease of turbot, it is characterised in that：Match somebody with somebody including fraction by weight
The following components of ratio：10~20 parts of Chinese gall, 25~35 parts of the Chinese bulbul, 45~55 parts of Cortex Phellodendri, 15~25 parts of Herba Andrographitis, Angelica sinensis 20
~35 parts, 15~25 parts of Radix Codonopsis, 12~24 parts of honeysuckle.
Can also be added in said components among the bark of eucommia, the bark of ash, frankincense, myrrh any one, it is two kinds any, any
Three kinds or any four.Wherein 10~20 parts of the bark of eucommia, 8~15 parts of the bark of ash, 6~15 parts of frankincense, 2~5 parts of myrrh.
Most preferred component is 20 parts of Chinese gall, 30 parts of the Chinese bulbul, 50 parts of Cortex Phellodendri, 20 parts of Herba Andrographitis, 25 parts of Angelica sinensis, Radix Codonopsis
20 parts, 20 parts of honeysuckle, 10 parts of the bark of eucommia, 8 parts of the bark of ash, 6 parts of frankincense, 5 parts of myrrh.
The preparation method of the medicine is：
1. by each component FW177 type crusher for Chinese herbal medicine, 24000r/min is crushed to 0.12mm sizes.
2. each component after crushing is weighed successively, is checked.
3. each component is added in V-type high efficient mixer, incorporation time is 30 minutes.
4. the semi-finished product mixed are fitted into plastic packaging bag, weigh, Self-enclosing, that is, finished product.
Experiment process is:
1. comparative formula
Compound 1：50 kilograms of Radix Isatidis；30 kilograms of the root of bidentate achyranthes, 40 kilograms of radix glycyrrhizae, 20 kilograms of dried orange peel, 40 kilograms of Chinese cassia tree, malt 20
Kilogram, 40 kilograms of Divine Comedy, 20 kilograms of the Chinese bulbul, 30 kilograms of Fructus Forsythiae, 20 kilograms of reed root.
Compound 2：40 kilograms of radix astragali, 40 kilograms of Radix Codonopsis, 40 kilograms of Rhizoma Atractylodis Macrocephalae, 30 kilograms of rheum officinale, 20 kilograms of Radix Isatidis, radix scutellariae 30
Kilogram, 30 kilograms of selfheal, 20 kilograms of wild chrysanthemum, 30 kilograms of moutan bark, 30 kilograms of Radix Isatidis.
Compound 3：It is 50 kilograms of the fruit of Chinese wolfberry, 40 kilograms of wilsonii, 40 kilograms of honeysuckle, 30 kilograms of radix astragali, 20 kilograms of chrysanthemum, big
30 kilograms of garlic, 20 kilograms of Radix Isatidis, 20 kilograms of the bark of ash, 30 kilograms of hawthorn, 30 kilograms of Canton love-pea vine, 20 kilograms of prepared rhizome of rehmannia
Most preferably component：20 kilograms of Chinese gall, 30 kilograms of the Chinese bulbul, 50 kilograms of Cortex Phellodendri, 20 kilograms of Herba Andrographitis, Angelica sinensis 25 are public
Jin, 20 kilograms of Radix Codonopsis, 20 kilograms of honeysuckle, 10 kilograms of the bark of eucommia, 8 kilograms of the bark of ash, 6 kilograms of frankincense, 5 kilograms of myrrh.
2. the preparation of feed
Above-mentioned four kinds of compounds are added in basal feed according to the additive capacity that mass fraction is 1.0% respectively.Add
The grit of 3.5 millimeters of diameter is made through feed processor for the feed of medicine, spare after dry.Basal feed formula be shown in Table 1. its
Gross protein value is 41.58%, crude fat 8.54%, moisture 12%, crude fibre 5%, calcium 4%, phosphorus 1%.
1 basal feed of table forms
3. experimental condition and management
Choose and suffer from black and thin sick turbot, totally 150 tail, is randomly divided into five groups, be respectively compound 1,2,3 groups, it is optimal
Group and control group are selected, is raised in 5 aquariums (130cm × 100cm × 80cm), every group of 30 tails.
Experimental group feeds corresponding feed, and control group feeds basal feed, and feeding rate is 2%, raises 30 days.
The water temperature of during the experiment has circulation filter pump and inflator pump, refreshes the water periodically and clean filter pulp at 22.8~28.3 DEG C, ties up
Dissolved oxygen is held in 5.4~7.6mg/L, for pH value 6.4~8.1, the concentration of control ammonia (NH3) is less than 0.02mg/L, control nitrous
The content of hydrochlorate (NO2-) is less than 0.20mg/L.
4. result of the test is as shown in table 2
Table 2：The necrology of turbot
By table 2 as it can be seen that the effect of most preferably component is best, the black and thin sick pathogenic bacteria of turbot can be effectively killed, are reduced
Turbot suffers from the black and thin sick death rate.
In conclusion the present invention is according to tcm theory, scientific compatibility, with modern means of science and technology to wherein most medicinal material
Active ingredient carry out quantitative, half-quantitative detection, obtained finished product, which can be killed effectively, causes the black and thin sick pathogen of turbot fish, respectively
Taste medicine acts synergistically, and not only strengthens the killing effect to pathogenic bacteria, but also reduces the toxicity of simple, to bacteriosis
There is significant prevention effect, be a kind of good effect, nuisanceless, noresidue, Chinese medicine easy to use, especially suitable for batch production
Extensive turbot fish culture.
Claims (2)
- A kind of 1. herbal composite that can effectively treat the black and thin disease of turbot, it is characterised in that：Matched including fraction by weight Following components：10~20 parts of Chinese gall, 25~35 parts of the Chinese bulbul, 45~55 parts of Cortex Phellodendri, 15~25 parts of Herba Andrographitis, Angelica sinensis 20~ 35 parts, 15~25 parts of Radix Codonopsis, 12~24 parts of honeysuckle, 10~20 parts of the bark of eucommia, 8~15 parts of the bark of ash, 6~15 parts of frankincense, myrrh 2~ 5 parts.
- A kind of 2. herbal composite that can effectively treat the black and thin disease of turbot according to claim 1, it is characterised in that： The component is 20 parts of Chinese gall, 30 parts of the Chinese bulbul, 50 parts of Cortex Phellodendri, 20 parts of Herba Andrographitis, 25 parts of Angelica sinensis, 20 parts of Radix Codonopsis, honeysuckle 20 parts, 10 parts of the bark of eucommia, 8 parts of the bark of ash, 6 parts of frankincense, 5 parts of myrrh.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610919306.6A CN107970303A (en) | 2016-10-21 | 2016-10-21 | A kind of herbal composite that can effectively treat the black and thin disease of turbot |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610919306.6A CN107970303A (en) | 2016-10-21 | 2016-10-21 | A kind of herbal composite that can effectively treat the black and thin disease of turbot |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107970303A true CN107970303A (en) | 2018-05-01 |
Family
ID=62004437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610919306.6A Pending CN107970303A (en) | 2016-10-21 | 2016-10-21 | A kind of herbal composite that can effectively treat the black and thin disease of turbot |
Country Status (1)
| Country | Link |
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| CN (1) | CN107970303A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111838456A (en) * | 2020-08-19 | 2020-10-30 | 河北师范大学 | Traditional Chinese medicine composition and turbot feed prepared from same |
| CN112273292A (en) * | 2020-11-25 | 2021-01-29 | 中国海洋大学 | Culture method of juvenile turbot |
-
2016
- 2016-10-21 CN CN201610919306.6A patent/CN107970303A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111838456A (en) * | 2020-08-19 | 2020-10-30 | 河北师范大学 | Traditional Chinese medicine composition and turbot feed prepared from same |
| CN112273292A (en) * | 2020-11-25 | 2021-01-29 | 中国海洋大学 | Culture method of juvenile turbot |
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180501 |
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| WD01 | Invention patent application deemed withdrawn after publication |