CN107969691A - A kind of composition that can effectively improve moisture of skin and preparation method thereof - Google Patents

A kind of composition that can effectively improve moisture of skin and preparation method thereof Download PDF

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Publication number
CN107969691A
CN107969691A CN201711218985.5A CN201711218985A CN107969691A CN 107969691 A CN107969691 A CN 107969691A CN 201711218985 A CN201711218985 A CN 201711218985A CN 107969691 A CN107969691 A CN 107969691A
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parts
bird
skin
composition
nest
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张宏
查圣华
张兴龙
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BEIJING TONGRENTANG HEALTH PHARMACEUTICAL Co Ltd
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BEIJING TONGRENTANG HEALTH PHARMACEUTICAL Co Ltd
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Priority to CN201711218985.5A priority Critical patent/CN107969691A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of composition that can effectively improve moisture of skin and preparation method thereof, belong to food processing technology field.This composition includes the component of following parts by weight:5 30 parts of bird's nests, 5 30 parts of collagens, 0.1 1 parts of Sodium Hyaluronates.The present composition is raw materials used common, and it is low to prepare easy to process and cost;The product philosophy being combined using traditional Chinese and western medicine theory, the improvement moisture of skin of multi-angle;Moisture of skin significant effect is improved using product made of the formula, synergistic effect is extremely obvious, and production method is easy, has good market popularization value.

Description

A kind of composition that can effectively improve moisture of skin and preparation method thereof
Technical field
The present invention relates to a kind of technical field of health care food, specifically, it is related to a kind of moisture of skin that can effectively improve Composition and preparation method thereof.
Background technology
Skin is one of organ of human body maximum, about the 16% of percentage of liveweight.The aging of skin can influence moisture in skin and contain Amount, while be also that skin lacks the one of the major reasons that moisture occurs.The aging of skin is divided into natural aging and light aging.It is natural Aging shows as fine wrinkles, cutis laxa, drying and coarse, reflect the loss of collagen, the reduction of dermal cell and Their secreted stromatins are related with the minor anomaly of epidermal differentiation.Light aging shows as loss of elasticity, and wrinkle is slightly deep, leather Sample appearance, is often accompanied by pigmentation.The traditional Chinese medical science thinks that skin water shortage belongs to traditional Chinese medicine and hinders Tianjin category.In the metabolic process of body fluid, Problem occurs for any one link in its generation, defeated cloth, excretion, can all influence body fluid metabolic process, causes what body fluid was metabolized It is abnormal, cause the deficiency of moisture of skin.
Hyaluronic acid, also known as sodium hyaluronate, are a kind of straight-chain polysaccharides of high molecular weight, are widely present in the connective group of organism In knitting, it is one of main matrix component of human skin epidermis, and people's hyaluronic acid contents highest in embryonic stage body, is born After gradually decrease.If in the human body of 20 years old hyaluronic acid relative amount positioning 100%, 30,50,60 years old when respectively under It is reduced to 65%, 45%, 25%.With the influence of the factor such as the growth and nutrition at people's age, sunshine, environment, human body synthesis is saturating The ability of bright matter acid is gradually reduced, and the content of hyaluronic acid can be reduced gradually in skin, when the hyaluronic acid contents in skin are low When certain level, the water content of skin surface can be reduced gradually, cause cuticula aging, and skin just seems coarse, wrinkles Line, follows the string, it appears aging, this phenomenon were generally present in after 25 years old, this is also middle-aged and elderly people and children's skin One of the main reason for gap.
Bird's nest is also known as delicacy made from bird's nests, Yan Gen, swallow vegetables, is a kind of rare Chinese medicine and health food, is known as " the roe in east Sauce ", " east treasure ", are recorded in earliest《Essentials of Materia Medica》And《This is through meeting original》, " bird's nest is sweet light flat, supports lung yin greatly, resolving sputum stops for meaning Cough.Mend and can be clear, to nurse one's health the panacea of consumptive disease ".The saliva and its plumage that bird's nest is secreted for a variety of birds of Apodidae aerodramus Suede is mixed and condensed in the nest built up on overhanging cliff.Its characteristic component is sialoglycoprotein.Traditional Chinese medicine thinks, saliva energy Moisten face, happy skin, solid tooth, strengthening the bones and muscles, venting QI-blood, life of lengthening the life.Li Shizhen (1518-1593 A.D.) is write at the same time《Compendium of Materia Medica》Describe " swallow Nest enters lung anger, enters kidney taste water, enter stomach tonifying spleen, mend without dry " the effect of.
From above mechanism study, the collagen and hyaluronic acid needed for skin histology are supplemented from doctor trained in Western medicine angle, together When traditional Chinese medical science angle strengthen promotion to body fluid to supplement qi of zang-fu viscera, take the photograph admittedly and gasification, can also moisture is smoothly reached Skin is to improve moisture of skin.
CN103005471A discloses a kind of health-caring capsule for improving moisture of skin, its raw material proportioning:Collagen 200- 230g, grape seed extract 35-50g, vitamin E powder 15-20g, aloe vera gel 6-10g, microcrystalline cellulose 60-80g, The invention can be effectively improved moisture of skin, but its improvement moisture of skin effect is very limited, it, which is equal to, uses single initial rubber Former albumen improve the effect of moisture of skin.
CN101653256A discloses a kind of production method of the health product capsule for beautifying face and moistering lotion, by capsule shell and Built-in pulvis composition, its built-in pulvis press following weight proportion:Bird's nest 0.5%-1%;Sodium Hyaluronate 5%-10%;Grape pip Extract 15%-25%;Water soluble pearl powder 5%-10%;Collagen 55%-60%;VC 2%-8%;VE 0.5%- 3%, the present invention has beautifying face and moistering lotion, the effect to slow down aging.Utilization collagen of the invention as other inventions routinely Improve moisture of skin with Sodium Hyaluronate, due to its formula and match unreasonable, bird's nest additive amount is few, does not find and says Bright bird's nest has the function of improving moisture of skin and the synergistic effect to collagen and hyaluronic acid, this product is also only Only it is to rely on to wave collagen and Sodium Hyaluronate improvement moisture of skin, effect is equally limited.
Find that mainstream applications depend on collagen in the product for improving moisture of skin at present through retrieval investigation, and Effect cannot meet existing market needs, and the product that market in urgent need more can efficiently improve moisture of skin occurs.
The content of the invention
In order to solve the above-mentioned technical problem the present invention provides a kind of composition that can effectively improve moisture of skin, the present invention adopts With the theory of the combination of Chinese tradiational and Western medicine, multi-angle removes improvement moisture of skin.Present composition main component is collagen, transparent Matter acid sodium and bird's nest, collagen and Sodium Hyaluronate can be effectively needed for complementary tissue collagen and hyaluronic acid, and then Cuticula aging is prevented, preventing the water content of skin surface reduces, and bird's nest pushes away body fluid to strengthen by supplementing qi of zang-fu viscera It is dynamic, take the photograph admittedly and gasification, and moisture is smoothly reached skin improves moisture of skin.
The technical solution that the present invention solves above-mentioned technical problem is as follows:A kind of composition that can effectively improve moisture of skin, Include the component of following parts by weight:
5-30 parts of bird's nests, 5-30 parts of collagens, 0.1-1 parts of Sodium Hyaluronates.
Based on the above technical solutions, the present invention can also be improved as follows.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
15-30 parts of bird's nests, 5-15 parts of collagens, 0.5-1 parts of Sodium Hyaluronates.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
5 parts of bird's nests, 5 parts of collagens, 0.1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
30 parts of bird's nests, 30 parts of collagens, 1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
5 parts of bird's nests, 5 parts of collagens, 1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
30 parts of bird's nests, 30 parts of collagens, 0.1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
5 parts of bird's nests, 30 parts of collagens, 1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
30 parts of bird's nests, 5 parts of collagens, 0.1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
20 parts of bird's nests, 20 parts of collagens, 1 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
20 parts of bird's nests, 20 parts of collagens, 0.5 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
28 parts of bird's nests, 10 parts of collagens, 0.6 part of Sodium Hyaluronate.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
15 parts of bird's nests, 15 parts of collagens, 0.4 part of Sodium Hyaluronate, 70 portions of rock sugar, 0.125 part of agar.
Further, a kind of composition that can effectively improve moisture of skin, includes the component of following parts by weight:
28 parts of bird's nests, 10 parts of collagens, 0.5 part of Sodium Hyaluronate, 70 portions of rock sugar, 0.125 part of agar.
In the composition that doctor trained in Western medicine theory is made of collagen and Sodium Hyaluronate, collagen can be that body supplements The collagen lost, triple-helix structure specific to collagen play a supporting role dermal tissue, and there is water lock to protect Wet function.And Sodium Hyaluronate can supplement corresponding hyaluronic acid, hyaluronic acid, which is naturally present in human skin, to be had There is the polymer of water retaining function, be mutually wound in continuous net structure between hyaluronan molecule chain, hydrone passes through polarity Key and hydrogen bond are directly acted on hyaluronic acid so that hyaluronic acid can absorb and keep its own weight as molecule sponge Thousands of times of moisture, is internationally recognized best moisturizer.
The present invention is on the basis of collagen and Sodium Hyaluronate compounding, and nearly hundred kinds of Chinese medicine materials are screened, With reference to traditional medicine to improve moisture of skin mechanism research, by many times grope to allocate, the composition finally selected is not Only simple synergistic effect, and also certain multiplication, maximumlly inspire composition for improved moisture of skin Effect.
Although conventional research shows, collagen and Sodium Hyaluronate can effectively improve moisture of skin, hair A person of good sense has found in practical study that after above-mentioned formula is allocated it improves the effect of moisture of skin and becomes apparent from, and bird's nest adds Collaboration multiplication can more be played the role of by adding.
When the composition that can effectively improve moisture of skin is only made of bird's nest, Sodium Hyaluronate and collagen, this hair It is bright that a kind of preparation method of the as described above composition that can effectively improve moisture of skin is also provided, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
When the composition that can effectively improve moisture of skin is made of bird's nest, Sodium Hyaluronate, collagen, rock sugar and agar When, the present invention also provides a kind of preparation method of the composition as described above that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) purified water of both 5-8 times of gross weights is added into rock sugar and agar, is heated to dissolving, 300 mesh sieves is crossed, obtains ice Sugared agar solution;
4) by the bird's nest after 1) handling, 2) gained mixed liquor and 3) after gained rock sugar agar solution mixes, purified water is added extremely 231 parts by weight, it is filling into bird's nest soup with white funguses.
The present invention can also pre-process bird's nest according to the actual requirements, and the different product shape such as pulvis, tablet and capsule is made Formula.
The present invention is the mechanism of skin water shortage to be carried out from traditional Chinese and western medicine angle comprehensively, after careful analysis, and then filter out swallow The efficient and without side-effects raw material such as nest, collagen, Sodium Hyaluronate is combined together, and can effectively improve moisture of skin.Separately Outside, composition each component of the invention collaboration multiplication effect is obvious, is found by establishing data model analysis to Optimal Experimental:① Collagen and Sodium Hyaluronate synergistic effect are obvious, can effectively improve moisture of skin;2. bird's nest can be greatly enhanced collagen Albumen sodium hyaluronate improves the effect of moisture of skin.
The inventors discovered that bird's nest can effectively improve moisture of skin, and tested through toxicological security experiment and function assessment Verification, bird's nest use at the same time with collagen sodium hyaluronate, improve the effect multiplication of moisture of skin, and safety is made without pair With can be long-term use of.
Embodiment
The principles and features of the present invention are described below, and the given examples are served only to explain the present invention, is not intended to limit Determine the scope of the present invention.
Embodiment 1
The composition that can effectively improve moisture of skin in the present embodiment is made of the component of following parts by weight:5 parts of bird's nests, 5 parts of collagens, 0.1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 2
The composition that can effectively improve moisture of skin in the present embodiment is made of the component of following parts by weight:30 portions of swallows Nest, 30 parts of collagens, 1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 3
The composition that can effectively improve moisture of skin in the present embodiment is made of the component of following parts by weight:5 parts of bird's nests, 5 parts of collagens, 1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 4
The composition that can effectively improve moisture of skin in the present embodiment is made of the component of following parts by weight:30 portions of swallows Nest, 30 parts of collagens, 0.1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 5
The composition that can effectively improve moisture of skin in the present embodiment is made of the component of following parts by weight:5 parts of bird's nests, 30 parts of collagens, 1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 6
The composition that moisture of skin is effectively improved in the present embodiment is made of the component of following parts by weight:30 parts of bird's nests, 5 Part collagen, 0.1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 7
The composition that moisture of skin is effectively improved in the present embodiment is made of the component of following parts by weight:20 parts of bird's nests, 20 parts of collagens, 1 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 8
The composition that moisture of skin is effectively improved in the present embodiment is made of the component of following parts by weight:20 parts of bird's nests, 20 parts of collagens, 0.5 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 9
The composition that moisture of skin is effectively improved in the present embodiment is made of the component of following parts by weight:28 parts of bird's nests, 10 parts of collagens, 0.6 part of Sodium Hyaluronate.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mix, addition purified water is filling into being to 231 parts by weight Eat bird's nest.
Embodiment 10
The composition that moisture of skin is effectively improved in the present embodiment is made of the component of following parts by weight:15 parts of bird's nests, 15 parts of collagens, 0.4 part of Sodium Hyaluronate, and other auxiliary materials of respective amount:70 portions of rock sugar, 0.125 part of agar.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) purified water of both 5-8 times of gross weights is added into rock sugar and agar, is heated to dissolving, 300 mesh sieves is crossed, obtains ice Sugared agar solution;
4) by the bird's nest after 1) handling, 2) gained mixed liquor and 3) after gained rock sugar agar solution mixes, purified water is added extremely 231 parts by weight, it is filling into bird's nest soup with white funguses.
Embodiment 11
The composition that moisture of skin is effectively improved in the present embodiment is made of the component of following parts by weight:28 parts of bird's nests, 10 parts of collagens, 0.5 part of Sodium Hyaluronate, and other auxiliary materials of respective amount:70 portions of rock sugar, 0.125 part of agar.
The preparation method of the above-mentioned composition that can effectively improve moisture of skin, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, and drying, must be handled Bird's nest afterwards;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, is stirred until homogeneous dissolving, Obtain mixed liquor;
3) purified water of both 5-8 times of gross weights is added into rock sugar and agar, is heated to dissolving, 300 mesh sieves is crossed, obtains ice Sugared agar solution;
4) by the bird's nest after 1) handling, 2) gained mixed liquor and 3) after gained rock sugar agar solution mixes, purified water is added extremely 231 parts by weight, it is filling into bird's nest soup with white funguses.
Experimental example one
The embodiment product that embodiment 9 is prepared carries out rat and feeds within 30 days experiment, and sample property is liquid, human body Oral recommended dose is daily 33g, because recommended dose is larger, then is tested after removing partial supplementary material sample, goes partial supplementary material Sample dose is 6g/ days, and adult's weight converts into that to remove partial supplementary material sample recommended dose be 0.1g/kbw by 60kg calculating. With reference to《Health food is examined and assessment technique specification》(version in 2003) using conventional mouse carry out acute oral toxicity test, Salmonella reversion test, mouse marrow cell micro nuclear test, mouse inbred strain examine product toxicity.
It was found that this goes auxiliary material product to be more than 15.00g/kbw to the maximum tolerated dose (MTD) of female, male mouse, belong to nontoxic Level.Ames experiments, mouse bone marrow polychromatic erythrocytes micronucleus test, mouse sperm deformity experimental result are feminine gender.With 2.50%th, sample incorporation feed is fed with rat 30 days by 5.00%, 10.00% ratio, and control group is raised with basal feed.Experiment Period, animal growth is good, each group dosage group weight, weightening, food utilization, routine blood indexes, blood biochemistry index, dirty Compared with the control group, there was no significant difference (P > 0.05) for the amount of thinking highly of and internal organs/weight ratio.Gross anatomy and histopathology inspection Look into the abnormal change for having no substantially related with sample.Illustrate that the sample is fed for 30 days and obvious toxic-side effects are had no to rat.
Experimental example two
The embodiment product that embodiment 1 to 11 is prepared according to《Health food is examined and assessment technique specification》(2003 Year version) carry out human feeding trial (moisture of test forehead glabella skin) to improving moisture of skin.
This experiment all subjects' age at 30-50 Sui, moisture of skin≤12, exclude gestation or women breast-feeding their children and There are the patients such as cardiovascular and cerebrovascular, liver, kidney, haematopoietic disorder.210 subjects are randomly divided into 14 groups, every group of 15 people.
Assay method:Good in spaciousness, ventilation condition, the inspection chamber that the space environment such as temperature, humidity is stablized carries out, and is pacifying The tested position of distilled water cleaning is dipped in cleaning cotton balls under quiet state, dries the latter 15 minutes measure for carrying out moisture content, test-meal is front and rear to survey Work calmly by same instrument, same to one man operation.
Control group takes placebo, 33g/ times, 1 time a day;
One group of positive control takes bird's nest, 4.29g/ times, 1 time a day;
Two groups of positive control takes Sodium Hyaluronate and collagen mixture, and (proportioning is collagen 4.29g, hyalomitome Sour sodium 0.14g), 4.43g/ times, 1 time a day;
Test one group and take the composition prepared in the embodiment of the present invention 1,33g/ times, 1 time a day (wherein containing bird's nest 0.71g, collagen 0.71g, Sodium Hyaluronate 0.01g);
Test two groups and take the composition prepared in the embodiment of the present invention 2,33g/ times, 1 time a day (wherein containing bird's nest 4.29g, collagen 4.29g, Sodium Hyaluronate 0.14g);
Test three groups and take the composition prepared in the embodiment of the present invention 3,33g/ times, 1 time a day (wherein containing bird's nest 0.71g, collagen 0.71g, Sodium Hyaluronate 0.14g);
Test four groups and take the composition prepared in the embodiment of the present invention 4,33g/ times, 1 time a day (wherein containing bird's nest 4.29g, collagen 4.29g, Sodium Hyaluronate 0.01g);
Test five groups and take the composition prepared in the embodiment of the present invention 5,33g/ times, 1 time a day (wherein containing bird's nest 0.71g, collagen 4.29g, Sodium Hyaluronate 0.14g);
Test six groups and take the composition prepared in the embodiment of the present invention 6,33g/ times, 1 time a day (wherein containing bird's nest 4.29g, collagen 0.71g, Sodium Hyaluronate 0.01g);
Test seven groups and take the composition prepared in the embodiment of the present invention 7,33g/ times, 1 time a day (wherein containing bird's nest 2.86g, collagen 2.86g, Sodium Hyaluronate 0.14g);
Test eight groups and take the composition prepared in the embodiment of the present invention 8,33g/ times, 1 time a day (wherein containing bird's nest 2.86g, collagen 2.86g, Sodium Hyaluronate 0.07g);
Test nine groups and take the composition prepared in the embodiment of the present invention 9,33g/ times, 1 time a day (wherein containing bird's nest 4.00g, collagen 1.43g, Sodium Hyaluronate 0.09g);
Test ten groups and take the composition prepared in the embodiment of the present invention 10,33g/ times, 1 time a day (wherein containing bird's nest 2.14g, collagen 2.14g, Sodium Hyaluronate 0.06g);
Test 11 groups and take the composition prepared in the embodiment of the present invention 11,33g/ times, 1 time a day (wherein containing bird's nest 4g, collagen 1.43g, Sodium Hyaluronate 0.07g).
Continuously taken 90 days according to above-mentioned experimental method, during the experiment subject does not change original life and diet is practised It is used, normal diet.
Table 1 tests the change of the moisture of front and rear subject's volume glabella skin
Group Moisture of skin before experiment Moisture of skin after experiment Rise percentage %
Control group 8.9±0.62 8.93±0.16 0.28%
One group of positive control 9±0.28 9.27±0.4 3.04%
Two groups of positive control 9.07±0.29 10.96±0.53** 20.80%
Test one group 8.9±0.22 11.12±0.74** 24.93%
Test two groups 8.99±0.31 12.6±0.22** 40.19%
Test three groups 8.88±0.3 11.28±0.76** 27.04%
Test four groups 9.02±0.35 12.05±0.41** 33.50%
Test five groups 9.02±0.25 11.69±0.99** 29.59%
Test six groups 9.05±0.28 11.76±0.72** 29.90%
Test seven groups 8.9±0.26 11.84±0.86** 33.03%
Test eight groups 9.03±0.26 11.92±0.68** 32.02%
Test nine groups 9±0.33 12.51±0.33** 39.01%
Test ten groups 9.08±0.25 11.97±0.89** 31.82%
Test 11 groups 9.01±0.24 12.61±0.31** 39.85%
Note:Compared with before taking, * is p < 0.05, and * * are P < 0.01.
As can be seen from the table, after the composition for taking the present invention, the moisture improvement of volume glabella skin is extremely notable, from One group of positive control can be seen that bird's nest improves moisture of skin almost without effect;But come from five groups of contrasts of two groups of experiment and experiment See, the synergistic effect of improvement skin moisture of the bird's nest to collagen sodium hyaluronate is notable, can be greatly enhanced glue Former albumen sodium hyaluronate improves the effect of moisture of skin.Two groups of skin moisture climbings 40.19% are tested, compared to sun Property control two groups and one group of positive control, effect is almost double, illustrate bird's nest and collagen sodium hyaluronate at the same time Use, improve the effect multiplication of moisture of skin.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and Within principle, any modification, equivalent replacement, improvement and so on, should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of composition that can effectively improve moisture of skin, it is characterised in that include the component of following parts by weight:
5-30 parts of bird's nests, 5-30 parts of collagens, 0.1-1 parts of Sodium Hyaluronates.
2. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
15-30 parts of bird's nests, 5-15 parts of collagens, 0.5-1 parts of Sodium Hyaluronates.
3. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
5 parts of bird's nests, 5 parts of collagens, 0.1 part of Sodium Hyaluronate.
4. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
30 parts of bird's nests, 30 parts of collagens, 1 part of Sodium Hyaluronate.
5. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
5 parts of bird's nests, 5 parts of collagens, 1 part of Sodium Hyaluronate.
6. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
30 parts of bird's nests, 30 parts of collagens, 0.1 part of Sodium Hyaluronate.
7. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
5 parts of bird's nests, 30 parts of collagens, 1 part of Sodium Hyaluronate;
Or a kind of composition that can effectively improve moisture of skin includes the component of following parts by weight:
30 parts of bird's nests, 5 parts of collagens, 0.1 part of Sodium Hyaluronate;
Or a kind of composition that can effectively improve moisture of skin includes the component of following parts by weight:
20 parts of bird's nests, 20 parts of collagens, 1 part of Sodium Hyaluronate;
Or a kind of composition that can effectively improve moisture of skin includes the component of following parts by weight:
20 parts of bird's nests, 20 parts of collagens, 0.5 part of Sodium Hyaluronate;
Or a kind of composition that can effectively improve moisture of skin includes the component of following parts by weight:
28 parts of bird's nests, 10 parts of collagens, 0.6 part of Sodium Hyaluronate.
8. a kind of composition that can effectively improve moisture of skin according to claim 1, it is characterised in that including following heavy Measure the component of number:
15 parts of bird's nests, 15 parts of collagens, 0.4 part of Sodium Hyaluronate, 70 portions of rock sugar, 0.125 part of agar;
Or, a kind of composition that can effectively improve moisture of skin includes the component of following parts by weight:
28 parts of bird's nests, 10 parts of collagens, 0.5 part of Sodium Hyaluronate, 70 portions of rock sugar, 0.125 part of agar.
9. a kind of preparation method for the composition that can effectively improve moisture of skin such as claim 1-7 any one of them, it is special Sign is, including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, drying, after must handling Bird's nest;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, dissolving is stirred until homogeneous, obtains mixed Close liquid;
3) by the bird's nest after 1) handling with after 2) gained mixed liquor mixes, addition purified water to 231 parts by weight of formula ratio, it is filling into Instant cubilose.
A kind of 10. preparation method of the composition as claimed in claim 8 that can effectively improve moisture of skin, it is characterised in that Including:
1) bird's nest is taken, the purified water for adding 3.5-4.5 times of bird's nest weight is soaked, foreign bodies, cleans, drying, after must handling Bird's nest;
2) purified water of both 5-8 times of gross weights is added into Sodium Hyaluronate and collagen, dissolving is stirred until homogeneous, obtains mixed Close liquid;
3) purified water of both 5-8 times of gross weights is added into rock sugar and agar, is heated to dissolving, 300 mesh sieves is crossed, obtains rock sugar fine jade Fat liquid;
4) by the bird's nest after 1) handling, 2) gained mixed liquor and 3) after gained rock sugar agar solution mixes, purified water is added to 231 weights Part is measured, it is filling into bird's nest soup with white funguses.
CN201711218985.5A 2017-11-28 2017-11-28 A kind of composition that can effectively improve moisture of skin and preparation method thereof Pending CN107969691A (en)

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Cited By (8)

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CN108851065A (en) * 2018-09-10 2018-11-23 大连臻理海洋科技有限公司 Anti-decrepit beauty food
CN110604301A (en) * 2019-09-04 2019-12-24 北京同仁堂健康药业股份有限公司 Cubilose beverage containing pomegranate extract and galacto-oligosaccharide and preparation method thereof
CN113142430A (en) * 2021-03-25 2021-07-23 大洲新燕(厦门)生物科技有限公司 Sodium hyaluronate composite beverage and preparation method thereof
CN113413328A (en) * 2021-07-02 2021-09-21 安创蓓康生物科技有限公司 Preparation method of anti-aging collagen peptide sodium hyaluronate oral drink
CN113975192A (en) * 2021-11-01 2022-01-28 嘉必优生物技术(武汉)股份有限公司 Anti-aging composition and application thereof
CN114158738A (en) * 2021-12-07 2022-03-11 喜园(广东)生物科技有限公司 Antioxidant beautifying cubilose collagen peptide composition and preparation method thereof
CN114903171A (en) * 2022-05-24 2022-08-16 闵乐晓 Hyaluronic acid beautifying bird's nest and preparation method thereof
CN116235945A (en) * 2023-01-14 2023-06-09 北京小仙炖生物科技有限公司 Preparation method of stewed bird's nest freeze-dried powder, stewed bird's nest freeze-dried powder and application thereof

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108851065A (en) * 2018-09-10 2018-11-23 大连臻理海洋科技有限公司 Anti-decrepit beauty food
CN110604301A (en) * 2019-09-04 2019-12-24 北京同仁堂健康药业股份有限公司 Cubilose beverage containing pomegranate extract and galacto-oligosaccharide and preparation method thereof
CN113142430A (en) * 2021-03-25 2021-07-23 大洲新燕(厦门)生物科技有限公司 Sodium hyaluronate composite beverage and preparation method thereof
CN113413328A (en) * 2021-07-02 2021-09-21 安创蓓康生物科技有限公司 Preparation method of anti-aging collagen peptide sodium hyaluronate oral drink
CN113975192A (en) * 2021-11-01 2022-01-28 嘉必优生物技术(武汉)股份有限公司 Anti-aging composition and application thereof
CN114158738A (en) * 2021-12-07 2022-03-11 喜园(广东)生物科技有限公司 Antioxidant beautifying cubilose collagen peptide composition and preparation method thereof
CN114903171A (en) * 2022-05-24 2022-08-16 闵乐晓 Hyaluronic acid beautifying bird's nest and preparation method thereof
CN116235945A (en) * 2023-01-14 2023-06-09 北京小仙炖生物科技有限公司 Preparation method of stewed bird's nest freeze-dried powder, stewed bird's nest freeze-dried powder and application thereof

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Application publication date: 20180501