CN1857415A - Health product for women to delay senility and its preparing process - Google Patents

Health product for women to delay senility and its preparing process Download PDF

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CN1857415A
CN1857415A CNA2006100461713A CN200610046171A CN1857415A CN 1857415 A CN1857415 A CN 1857415A CN A2006100461713 A CNA2006100461713 A CN A2006100461713A CN 200610046171 A CN200610046171 A CN 200610046171A CN 1857415 A CN1857415 A CN 1857415A
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vitamin
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margarita
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张丽英
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Abstract

The present invention relates to health food, and especially a kind of health product for women to delay senility. The health product for women with obvious functions of delaying senility and no toxic side effect is compounded with ten kinds of medicinal materials, including deer fetus, ass-hide gelatin, lotus leaf, vitamin C, soybean isoflavone, etc in certain weight proportion.

Description

A kind of health product for women to delay senility and reparation technology method thereof
Technical field
The present invention relates to the health food industry, is a kind of health food and manufacturing technique method thereof of women to delay senility specifically.
Background technology
Along with the continuous progress of society, the continuous enhancing of people's living standard and health perception, health food more and more receives the concern of the whole society as a kind of effective illness prevention and fitness product.But the health product of the women to delay senility that state is extrapolated, its Main Ingredients and Appearance contain a large amount of chemosynthesis estrogen, and it is bigger that human body is had side effects.
Summary of the invention
The purpose of a kind of health product for women to delay senility of the present invention and reparation technology method thereof is, there are drawbacks such as side effect is bigger in anti-aging or Women health food at Traditional Female, adopts Embryo cervi, the various Chinese herbal medicine of Colla Corii Asini and vitamin V E, the various raw materials of Vc produce health product, reach the effect that toxic and side effects is little, effect is good.
A kind of health product for women to delay senility is by Embryo cervi or Placenta Hominis, Colla Corii Asini, Folium Nelumbinis, Radix Glycyrrhizae, Radix Ginseng, Flos Carthami, Margarita, vitamin V E, the various Chinese herbal medicine of vitamin V c and soybean isoflavone form, it is characterized in that:
Composition of raw materials and weight thereof (%) ratio:
Embryo cervi or Placenta Hominis 20-30 Flos Carthami 4-10 Colla Corii Asini 10-20
Margarita 3-9 Folium Nelumbinis 5-15 vitamin V E3-9
Radix Glycyrrhizae 5-15 vitamin V c 2-7 Radix Ginseng 5-15
Soybean isoflavone 2-7
A kind of reparation technology method of health product for women to delay senility is characterized in that:
1) Embryo cervi or Placenta Hominis, Colla Corii Asini are dried through 60-80 ℃ of temperature, and water content should be lower than 10%, then changes pulverizing process over to, and grinding particle size should be the 80-120 order, afterwards, can take by weighing standby by formula ratio;
2) Folium Nelumbinis, Radix Glycyrrhizae, Flos Carthami, 4 kinds of raw medicinal materials of Radix Ginseng at first should enter removal of impurity operation respectively, change the immersion operation over to after removing impurity, soak time is 3.5-4.5 hour, and temperature 80-100 ℃, the water yield that adds 10 times is extracted, time 1-2 hour, then enter for the first time and filter, filtrate changes combining process over to, filtering residue adds 8 times of water yields again, temperature is at 100 ℃, and the time is 1 hour, then carries out the second time and filters, filtrate also changes combining process over to for the second time, and filtering residue is discarded; Filtrate after the merging changes enrichment process over to, and the proportion that makes mixed liquor is 1.2-1.4, should enter the drying under reduced pressure operation afterwards, raw material water content≤10 after drying; Then enter pulverizing process, grinding particle size 80-100 order afterwards can be standby by the prescription metering;
3) powder vitamin V E, powder vitamin V c, Margarita powder, soybean isoflavone, directly standby by the formulation content metering;
4) above-mentioned various raw material is through pretreated material, press prescription and weight (%) thereof than after the weighing, put into batch mixer and carry out batch mixing, after fully mixing, change sterilization process over to, sterilising temp 65-75 ℃, disinfecting action should intermittently carry out 2-3 time, and is each 1-2 hour, qualified through the intermediate chemical examination again, make capsule or tablet, perhaps pill or granule; Be finished product through packing again.
Material combination foundation of the present invention:
1) Embryo cervi: put down in writing according to " herbal classic is met former ": Embryo cervi is " key medicine of temperature compensation essence and blood, and do not have the trouble of hot impairment of YIN ", " be preferably take a tonic or nourishing food to build up one's health innocent, the good agent of growing the few fire of benefit ".This medicine is grown the resistance QI invigorating, the regulating menstruation cold expelling, and gentle conditioning does not fire gas, is used for the treatment of women's deficiency of vital energy cold in blood, menoxenia, menalgia disease, is regarded as the sage of gynecological by ancient Chinese medicine doctor since ancient times always.Compendium of Material Medica: " Embryo cervi: menstruation-regulating face-beautifying.Separate all poison ... "." Chinese medical dictionary ": " Embryo cervi, the tire of female deer also.Gan Wen is nontoxic.It is true to take a tonic or nourishing food to build up one's health unit, grows the few fire of benefit ... "." Chinese medicine speech sea ": " Embryo cervi: spermatogenesis is mended marrow, tonifying blood and regulating menstruation ... "." Traditional Chinese Medicine ": " Embryo cervi is the in love product of flesh and blood, nourishing the most, benefiting QI and nourishing blood, promoting tissue regeneration by removing blood stasis ... "." national Chinese herbal medicine compilation ": " Embryo cervi cures mainly deficiency of kidney essence, weak unable, lassitude loin and legs, deficient qi and blood ... ".Modern science and technology confirm: contain 18 seed amino acids in the Embryo cervi; 22 kinds of inorganic elementss; Various vitamin and a small amount of hormone are rich in the aging resistance factor/SOD and epithelical cell growth factor, polypeptide element.
2) Colla Corii Asini: for donkey skin through decocting, concentrate the solid gum of making.Sweet in the mouth, flat is returned lung, Liver and kidney warp.Function cures mainly and is the YIN nourishing of enriching blood, and moisturizes, stops blooding, and is used for blood deficiency and yellow complexion, dizzy cardiopalmus, flesh unable, the dysphoria and insomnia that withers.Modern medicine study proves, contains glutin and several amino acids.Erythrocyte, haemachrome generation there is facilitation.
3) Folium Nelumbinis: bitter, puckery, flat.GUIXIN, liver, spleen channel." key to diagnosis and treatment " cloud: Folium Nelumbinis is obeyed it, makes us thin bad, can the disappear gas of YANG edema edema of single clothes.Be used for that the greasy skin of Simple Obesity, light, administration's diarrhea due to damp pathogen rush down, dizzy, diarrhea due to hypofunction of the spleen and multiple hemorrhage.Modern pharmacological research shows: Folium Nelumbinis contains and connects alkali, nuciferine, inferior U.S. opium poppy alkali, pronuciferine (+)-Pronuciferine, N-nornuciferine, the long-pending alkali of the goose palm, quercetin, organic acid, has relieving cough and expelling phlegm, antibacterial action.
4) Radix Glycyrrhizae: the property leaf is sweet, flat; GUIXIN, stomach, lung, spleen channel.Function cures mainly: invigorating the spleen and replenishing QI, and heat-clearing and toxic substances removing, so coordinating the actions of various ingredients in a prescription is for making.Be used for a little less than spleen, the insufficiency of stomach fatigue and weakness, shortness of breath and palpitation, but cushion toxicity, strong.The chemical constituent of Radix Glycyrrhizae: glycyrrhizin, enoxolone.Flavone compound, liquiritin, liquiritigenin, different Radix Glycyrrhizae (unit) pharmacological action: the effect of the ketone of antiinflammatory, antibiotic, antiallergic, nonspecific immunostimulant and saloid 17-hydroxy-11-dehydrocorticosterone deoxidation cortex.
5) Flos Carthami: hot, warm.GUIXIN, Liver Channel.Compendium of Material Medica record: Flos Carthami can " invigorate blood circulation moisturize, pain-relieving powder for treating swells, stimulate the menstrual flow ".Flos Carthami is gone into the heart, liver blood branch, grasps the hot logical property of temperature of loosing, can blood circulation promoting and blood stasis dispelling, and logical regulating menstruation arteries and veins, it is dark to be used for the macule color of warm blood due to stagnant, dysmenorrhea, amenorrhea due to stagnation of blood.The merit of this product blood circulation promoting and blood stasis dispelling is excellent, is widely used in the disease of the multiple stagnation of blood stasis of clinical each section for trouble or hematogenous blockage in recent years.
6) Radix Ginseng: Radix Ginseng is sweet, and little hardship, flat is returned spleen, lung, heart channel, has strongly invigorating primordial QI, and multiple arteries and veins takes off the merit of calming the nerves admittedly.Be used for body void, shortness of breath and fatigue, palpitation with fear insomnia, modern medicine study proves, the ginsenoside can QI invigorating, hemopoietic, help essence, calm the nerves.
7) Margarita: Margarita is sweet, salty, cold, GUIXIN, Liver Channel, the arresting convulsion of calming the nerves, and removing toxic substances and promoting granulation, the removing nebula that makes eye bright, anti-ageing preserving youthful looks is used for the palpitation with fear insomnia, and skin infection is not held back disease.
8) powder vitamin V E: vitamin V EBe antioxidant, can eliminate " free radical " that destroy cell in the body, stop the chain reaction of oxidation, prevent the destruction and the variation of cell, have antioxidation and end old and feeble effect.
9) powder vitamin V c: vitamin V c is L-ascorbic acid and antioxidant, has the pigmentation of preventing and improves immune function in delaying senility.
10) soybean isoflavone: with the Semen sojae atricolor defat dregs of rice is raw material, makes through extraction, chromatography and extraction process.Isoflavone levels is about 3% in the Semen sojae atricolor.The isoflavone content 40% that this product adopts, main chemical are daidzin, big legumin, genistein.Be described as " phytoestrogen, be supplementary " preferably.
In sum, be monarch with Embryo cervi, Colla Corii Asini, Radix Ginseng, soybean isoflavone, Margarita, Folium Nelumbinis, Flos Carthami are minister, with vitamin V E, vitamin V c for the assistant, Radix Glycyrrhizae plays the health care of slow down aging jointly for making.
The mechanism of product slow down aging of the present invention: this product adopts biotechnology to draw plant essence (embryo's element, plant isoflavone, Colla Corii Asini, ginsenoside, vitamin V E, vitamin V c), by nourish liking the ripple body, under the effect of enzyme, endogenous ground increases the content of female estrogen, sebum and the hydrophilic factor, makes skin delicacy, moist, flexible, the Feng Ting breast improves voluptus, really nourishing woman from inside to outside; Increase the hydrophilic factor, make skin gloss, delicacy, high resilience; Prolong follicular phase, allow young 8-10 of female pathology age year; Increase estrogen secretion, the Feng Ting breast improves voluptus, improves menopause syndrome.
Be suitable for the crowd: be applicable to 1) and normally drink water every day that skin is but still dry, coarse; It is also wizened, tightly drawn to bathe the back skin, still hydropenia; 2) be applicable to and do not stay up late and tired, still feel tired, sore waist and aching in the waist and the back, cold limbs and aversion to cold, listless; 3) be applicable to and quantitatively take vitamin, also often patronize the beauty parlor, still seen sallow face and fine and closely woven wrinkle; 4) be applicable to that 25-45 year, graceful bearing was young just, vaginal dryness but occurred, the lubricating fluid secretion reduces, and pleasant sensation reduces; 5) be applicable to recessive climacteric and menstrual period syndrome, as hectic fever, sweating, abdomen rise stomachache, exciting irritability, lead off and influence goodwill as between spouses and family harmony especially wantonly.
Toxicity test: pass through the acute toxicity test of large and small Mus per os, three genetic toxicity tests (Salmonella reversion test, PCEMNR micronucleus test, mouse sperm deformity test), rat traditional teratogenicity test and 30 days feeding trials of rat according to Liaoning Province inspection body of health monitoring institutions.GB15193-94 judges as follows to assay according to " toxicological evaluation of food safety procedure and method ":
Under this laboratory condition, product of the present invention to the large and small Mus per os acute toxicity of two kinds of sexes all greater than 10.00g/kg.bw, according to the acute toxicity classification, true border non-poisonous material; The result is all negative for three genetic toxicity tests (Salmonella reversion test, PCEMNR micronucleus test, mouse sperm deformity test); Rat traditional teratogenicity test result shows no teratogenesis; Experimental group that clinical examination in 30 days feeding trials of rat, internal organs weighing, blood biochemical are learned and checked, the hematological examination result shows each inspection item and matched group comparison, difference is not remarkable.The result of histopathologic examination shows, matched group and high dose group are female, male rat liver, kidney, stomach, intestinal are not all found obvious damaging pathological change.
Test effect is estimated: through Liaoning Province health monitoring institutions product of the present invention is carried out the test of deferring senility, judge according to " the function assessment assessment process and the detection method of health food ": this product has the function of slow down aging.
Per os gave this product of aged mouse various dose after 44 days, compare with the blank group: the myocardium lipofuscin content of high dose (0.80g/kg.bw) group reduces by 30 (p<0.05), serum activity of SOD improves 17% (p<0.05), and the whole blood glutathione peroxidase activity improves 19% (p<0.05).Each dosage group body weight does not all have significant difference (p<0.05) before and after the experiment.Compare with blank group (being tried substrate concentration 0%), tried substrate concentration 0.053% female fruit bat average life and prolonged 5% (p<0.05), maximum life span prolongs 2% (p<0.01), and the half death time prolongs 4 days, and male fruit bat average life prolongs 4% (p<0.05).The female fruit bat average life that is tried substrate concentration 0.160% prolongs 5% (p<0.05); Male fruit bat average life prolongs 5% (p<0.01), and maximum life span prolongs 3% (p<0.05).The female fruit bat average life that is tried substrate concentration 0.480% prolongs 7% (p<0.001), and maximum life span prolongs 3% (p<0.001); Male fruit bat average life prolongs 4% (p<0.05), and maximum life span prolongs 2% (p<0.05).
Good effect of the present invention is that raw material is easy to get, and needed raw material is traditional Chinese herbal medicine; Production technology is simple, adopts conventional drying chamber, pulverizer, grinder, filter, and equipment does not have specific (special) requirements; Product has no side effect, can be relieved, slow down aging safely, and play diseases prevention effectively and be healthy and strong and preserve the effect in youth.
Description of drawings
Fig. 1 is a process chart of the present invention.
The specific embodiment
Further specify as follows in conjunction with the accompanying drawings to product of the present invention and process.
Embodiment 1
A kind of health product for women to delay senility of the present invention, its prescription and component content weight (%) ratio:
Embryo cervi or Placenta Hominis 30 Flos Carthamis 10 Colla Corii Asini 20
Margarita 3 Folium Nelumbinis 15 vitamin Vs E3
Radix Glycyrrhizae 5 vitamin V c 2 Radix Ginsengs 5
Soybean isoflavone 7
Reparation technology method of the present invention is:
1) Embryo cervi or Placenta Hominis, Colla Corii Asini are dried through 60-80 ℃ of temperature, and water content should be lower than 10%, then changes pulverizing process over to, and grinding particle size should be the 80-120 order, afterwards, can take by weighing standby by formula ratio;
2) Folium Nelumbinis, Radix Glycyrrhizae, Flos Carthami, 4 kinds of raw medicinal materials of Radix Ginseng, at first should enter removal of impurity operation respectively, adopt manual cleaning way to remove raw material impurity, change the immersion operation over to after removing impurity, soak time is 3.5-4.5 hour, temperature 80-100 ℃, the water yield that adds 10 times is extracted, time 1-2 hour, then enter for the first time and filter, filtrate changes combining process over to, and filtering residue adds 8 times of water yields again, and temperature is at 100 ℃, time is 1 hour, then carry out the second time and filter, filtrate also changes combining process over to for the second time, and filtering residue is discarded; Filtrate after the merging changes enrichment process over to, and the proportion that makes mixed liquor is 1.2-1.4, should enter the drying under reduced pressure operation afterwards, raw material water content≤10 after drying; Then enter pulverizing process, grinding particle size 80-100 order afterwards can be standby by the prescription metering;
3) powder vitamin V E, powder vitamin V c, Margarita powder, soybean isoflavone, directly standby by the formulation content metering;
According to above-mentioned prescription and the various standby raw materials of content weighing, Embryo cervi 300kg, Colla Corii Asini 200kg, Folium Nelumbinis 150kg, Radix Glycyrrhizae 50kg, Radix Ginseng 50kg, Flos Carthami 100kg, Margarita 30kg, vitamin V E30kg, vitamin V c 20kg, soybean isoflavone 70kg; Put into batch mixer and carry out batch mixing, change sterilization process behind the mix homogeneously over to, 65 ℃ of sterilising temps, disinfecting action carry out 2 times at interval, sterilize 1 hour at every turn, and be qualified through the intermediate chemical examination again, makes capsule or tablet; Make finished product (please see Fig. 1 for details) through packing again.
Embodiment 2
Produce product of the present invention.
To pretreated various standby raw material, compare by prescription and content weight (%):
Placenta Hominis accounts for 20, Colla Corii Asini accounts for 10, Folium Nelumbinis accounts for 14, Radix Glycyrrhizae accounts for 15, Radix Ginseng accounts for 10, Flos Carthami accounts for 4, Margarita accounts for 9, V EAccount for 9, Vc accounts for 7, the different yellow groove of Semen sojae atricolor accounts for 2; The standby raw material of weighing, Placenta Hominis 200kg, Colla Corii Asini 100kg, Folium Nelumbinis 140kg, Radix Glycyrrhizae 150kg, Radix Ginseng 100kg, Flos Carthami 40kg, Margarita 90kg, V E90kg, Vc70kg, soybean isoflavone 20kg in the batch mixer of packing into, sterilize behind the mix homogeneously, 75 ℃ of sterilising temps intermittently carry out three sterilizations, sterilize 2 hours at every turn, again after intermediate chemical examination is qualified, make pill or granule afterwards, through packing finished product.Other operations and technical conditions are all with embodiment 1.
Embodiment 3
Produce product of the present invention.
By prescription of the present invention and component content weight (%) ratio, Embryo cervi accounts for 25, Colla Corii Asini accounts for 15, Folium Nelumbinis accounts for 10, Radix Glycyrrhizae accounts for 10, Radix Ginseng accounts for 10, Flos Carthami accounts for 9, Margarita accounts for 6, vitamin V EAccount for 6, vitamin V c accounts for 5, soybean isoflavone accounts for 4; Weighing above-mentioned raw materials: Embryo cervi 250kg, Colla Corii Asini 150kg, Folium Nelumbinis 100kg, Radix Glycyrrhizae 100kg, Flos Carthami 90kg, Radix Ginseng 100kg, Margarita 60kg, V E60kg, Vc50kg, soybean isoflavone 40kg; After the above-mentioned raw materials weighing, the blender of packing into changes sterilization process over to behind the mix homogeneously, be heated to 70 ℃, lasts 1 hour, and consecutive intervals carries out twice sterilization, makes capsule again after the intermediate chemical examination is qualified, is finished product through packing.Other process conditions and embodiment 1 all with.
Embodiment 4
Produce product of the present invention.Press prescription of the present invention and component weight (%): Embryo cervi 30, Colla Corii Asini 15, Folium Nelumbinis 5, Radix Glycyrrhizae 15, Radix Ginseng 15, Flos Carthami 5, Margarita 5, V E4, the ratio of Vc3, soybean isoflavone 3, the above-mentioned standby raw material of weighing: Embryo cervi 300kg, Colla Corii Asini 150kg, Folium Nelumbinis 50kg, Radix Glycyrrhizae 150kg, Radix Ginseng 150kg, Flos Carthami 50kg, Margarita 50kg, V E40kg, Vc30kg, soybean isoflavone 30kg; The raw material that above-mentioned weighing the finishes batch mixer of packing into through fully mixing the laggard operation of going into to sterilize, and intermittently carries out three sterilizations, changes the intermediate chemical examination again over to, enters packaging process after qualified, promptly produces finished product.Other process conditions and technical parameter are all with embodiment 1.

Claims (2)

1. a health product for women to delay senility is by Embryo cervi or Placenta Hominis, Colla Corii Asini, Folium Nelumbinis, Radix Glycyrrhizae, Radix Ginseng, Flos Carthami, Margarita, vitamin V E, the various Chinese herbal medicine of vitamin V c and soybean isoflavone form, it is characterized in that:
Composition of raw materials and weight thereof (%) ratio:
Embryo cervi or Placenta Hominis 20-30 Flos Carthami 4-10 Colla Corii Asini 10-20
Margarita 3-9 Folium Nelumbinis 5-15 vitamin V E3-9
Radix Glycyrrhizae 5-15 vitamin V c 2-7 Radix Ginseng 5-15
Soybean isoflavone 2-7.
2. according to the reparation technology method of the described a kind of health product for women to delay senility of claim 1, it is characterized in that:
1) Embryo cervi or Placenta Hominis, Colla Corii Asini are dried through 60-80 ℃ of temperature, and water content should be lower than 10%, then changes pulverizing process over to, and grinding particle size should be the 80-120 order, afterwards, can take by weighing standby by prescription;
2) Folium Nelumbinis, Radix Glycyrrhizae, Flos Carthami, 4 kinds of raw medicinal materials of Radix Ginseng at first should enter removal of impurity operation respectively, change the immersion operation over to after removing impurity, soak time is 3.5-4.5 hour, and temperature 80-100 ℃, the water yield that adds 10 times is extracted, time 1-2 hour, then enter for the first time and filter, filtrate changes combining process over to, filtering residue adds 8 times of water yields again, temperature is at 100 ℃, and the time is 1 hour, then carries out the second time and filters, filtrate also changes combining process over to for the second time, and filtering residue is discarded; Filtrate after the merging changes enrichment process over to, and the proportion that makes amalgamation liquid is 1.2-1.4, should enter the drying under reduced pressure operation afterwards, raw material water content≤10 after drying; Then enter pulverizing process, grinding particle size 100 orders afterwards can be standby by the prescription metering;
3) powder vitamin V E, powder vitamin V c, Margarita powder, soybean isoflavone, directly standby by the formulation content metering;
4) above-mentioned various raw material is through pretreated material, after prescription and weight (%) weighing thereof, put into batch mixer, after fully mixing, change sterilization process over to, sterilising temp 65-75 ℃, disinfecting action should intermittently carry out 2-3 time, each 1-2 hour, qualified through the intermediate chemical examination again, make capsule or tablet, perhaps pill, perhaps granule; Be finished product through packing again.
CNA2006100461713A 2006-03-24 2006-03-24 Health product for women to delay senility and its preparing process Pending CN1857415A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101869275A (en) * 2010-05-28 2010-10-27 吉林省健今药业股份有限公司 Deer embryo ginseng anti-aging health care medicinal granules
CN101253977B (en) * 2008-04-09 2012-05-30 黎秋萍 Antioxidation anti-aging disease prevention biological food product
CN101874621B (en) * 2009-11-05 2012-09-05 蒋小明 Deer placenta pearl capsules and preparation method thereof
CN102872266A (en) * 2012-10-09 2013-01-16 吉林大学 Fetus cervi compound medicinal preparation and method for preparing same
CN104286832A (en) * 2013-07-17 2015-01-21 吉林吉春制药股份有限公司 Health-care product with efficacy of enhancing immunity and removing chloasma, and preparation method thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101253977B (en) * 2008-04-09 2012-05-30 黎秋萍 Antioxidation anti-aging disease prevention biological food product
CN101874621B (en) * 2009-11-05 2012-09-05 蒋小明 Deer placenta pearl capsules and preparation method thereof
CN101869275A (en) * 2010-05-28 2010-10-27 吉林省健今药业股份有限公司 Deer embryo ginseng anti-aging health care medicinal granules
CN101869275B (en) * 2010-05-28 2012-11-14 吉林省健今药业股份有限公司 Deer embryo ginseng anti-aging health care medicinal granules
CN102872266A (en) * 2012-10-09 2013-01-16 吉林大学 Fetus cervi compound medicinal preparation and method for preparing same
CN102872266B (en) * 2012-10-09 2015-01-14 吉林大学 Fetus cervi compound medicinal preparation and method for preparing same
CN104286832A (en) * 2013-07-17 2015-01-21 吉林吉春制药股份有限公司 Health-care product with efficacy of enhancing immunity and removing chloasma, and preparation method thereof
CN104286832B (en) * 2013-07-17 2016-03-30 吉林吉春制药股份有限公司 A kind of health products and preparation method thereof with develop immunitypty, functions of removing chloasma effect

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