CN107929792A - A kind of activated carbon fibre dressing with pain-relieving functions and preparation method thereof - Google Patents

A kind of activated carbon fibre dressing with pain-relieving functions and preparation method thereof Download PDF

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Publication number
CN107929792A
CN107929792A CN201711356276.3A CN201711356276A CN107929792A CN 107929792 A CN107929792 A CN 107929792A CN 201711356276 A CN201711356276 A CN 201711356276A CN 107929792 A CN107929792 A CN 107929792A
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activated carbon
parts
carbon fibre
pain
dressing
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陈锦涛
韦加娜
熊亮
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Guangdong Taibao Medical Science Technology Co Ltd
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Guangdong Taibao Medical Science Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to medical dressing technical field, disclose a kind of activated carbon fibre dressing with pain-relieving functions and preparation method thereof, the dressing includes activated carbon fiber layers, electret layer, pressure sensitive adhesive layer and the honey positioned at activated carbon fibre layer surface and relieves pain film, and electret layer is between activated carbon fiber layers and pressure sensitive adhesive layer.Optimization design of the invention by structure, and the process modification of dressing preparation method, on the basis of existing Wound dressing technology, significantly enhance its antibacterial, anti-inflammatory, analgesic so that the healing time of wound further shortens.The preparation process of composite material prepared by present invention processing is without special installation, reaction condition is gentle, technical maturity, is suitable for industrial large-scale production.

Description

A kind of activated carbon fibre dressing with pain-relieving functions and preparation method thereof
Technical field
The present invention relates to medical dressing technical field, and in particular to a kind of activated carbon fibre dressing with pain-relieving functions and Its preparation method.
Background technology
In daily life, due to inevitably being stimulated be subject to the external world, such as knife cuts, burns, having one's hair waved, causes wound Appearance, and pain is usually associated with the appearance of wound and produces.Therefore, how nuring wound while, alleviate wound bring Pain all the time be test medical worker a great problem.
In the prior art, for treating the patch that pain is mainly various drug containing, its main function is to pass through human body Affected part the absorption of medicine is acted, sometimes inevitably produce side effect.Other treatment means are generally simple thing Reason mode, although of short duration effect can be obtained, good times don't last long.And compare the electrostatic ionic promoted the use of at present and sense the pain technology that disappears Affected part mainly is directly acted on using electrostatic ionic sensing, is effectively inhibiting abnormal cell growth, activation benign cell just It is frequently grown, works in the electrostatic field of particular polarity and intensity, makes the tissues such as the bone in affected part, muscle, blood vessel, neural joint Dielectric polarize, suppress the abnormal generation of cell, while blood circulation can be accelerated, improve neurophysiologic systems, rise To relieve pain, the effect for the pain that disappears.Although this method Considerable effect that treatment pain is sensed by electrostatic ionic, few at present For the pain of wound, and mostly it is the pain applied to Bones and joints.
The content of the invention
The purpose of the present invention is to solve deficiency of the existing wound dressing when treating or alleviating wound pain, there is provided A kind of activated carbon fibre dressing with pain-relieving functions.
To achieve these goals, technical solution provided by the invention is:
A kind of activated carbon fibre dressing with pain-relieving functions, including peel ply, activated carbon fiber layers and pressure sensitive adhesive layer, it is described Electret layer is equipped between activated carbon fiber layers and the pressure sensitive adhesive layer, the surface of the activated carbon fiber layers is covered with one layer Honey relieves pain film, and honey analgesic film includes the raw material of following parts by weight:50-60 parts of honey, 40-50 parts of glycerine, allantois 3-7 parts plain, 1-5 parts of citric acid, 200-250 parts of pure water, 10-20 parts of aloe, 5-10 parts of fish pelargonium, rose extract 12-18 Part, 20-30 parts of grape pip powder.
Preferably, the electret is process by polytetrafluoroethylene film through ion build up process.
Preferably, electret can be completely covered for the activated carbon fibre.
The preparation method of the above-mentioned activated carbon fibre dressing with pain-relieving functions is as follows:
(1)Aloe, fish pelargonium, rose extract, grape pip powder are weighed by weight, are cleaned and are pulverized, are placed into volatile oil extractor In, add the water of 5-10 times of weight, put and be slowly heated to seethe with excitement in electric jacket, keep 4 ~ 8h, stop heating a moment, collect volatile oil a;
(2)Honey, glycerine, allantoin, citric acid and pure water are weighed by weight, and heating is boiled, and filtering and concentrating obtains medicinal extract b;
(3)The surface of activated carbon fibre is modified:By FeCl of the activated carbon fibre through mass fraction 1 ~ 20%3Solution dipping 60 ~ 120min;
(4)Volatile oil a and medicinal extract b are placed in reactor, are sufficiently mixed simultaneously heated at constant temperature, will be through step(3)Modified activity Carbon fibe is impregnated in wherein, is then freeze-dried, then the activated carbon fibre and electret, pressure sensitive adhesive layer are pressed structure sheaf successively Secondary for composite, most irradiation sterilization after independent packaging afterwards to obtain the final product.
Further, above-mentioned steps(4)In heating-up temperature be 80 ~ 120 DEG C.
Further, above-mentioned steps(4)In dip time be 15 ~ 30min, active carbon fibre dimension table in obtained dressing The thickness of the honey analgesic film of face load is 25 ~ 50 μm.
Allantoin is the derivative of uric acid, fairly obvious to the Healing of skin.Tissue can be promoted to produce naturally clear Creation is used, and removes downright bad material;Cell Proliferation can be obviously promoted, granulation tissue is grown up rapidly, shortens healing time.Using It after liquid dressing, can not only mitigate wound pain, also have good antiinflammation, strengthen healing effect.
Asparagus juice is natural plant raw material, it contains polysaccharide, similar to hyaluronic acid, has lubrication well and moisturizing to make With.
Honey is the honey that the nectar that insect honey bee is adopted from the flowering plant's flowers is brewed in honeycomb, its containing glucose, Fructose, sucrose elite, a large amount of protein, cellulose components, delicate skin can be moistened by acting on skin surface, be a kind of good Water-based moisturizing ingredient, has moisturizing, moistens, antibacterial anti-inflammatory analgesia, only necrotic tissue and promoting muscle growing, promotes function of tissue regeneration.
The present invention can produce following beneficial effect:1)Activated carbon fiber layers can absorb wound exudate, keep skin wet, and And lubrication and moisture-keeping function are played jointly with functional components such as asparagus juices, build a good environment for wound healing;2) Under the collective effect of functional component honey and allantoin, its antibacterial and anti-inflammation functions is obvious;3)In the electrostatic ionic of electret layer Under the synergy of induction effect and honey, wound pain can be mitigated, it might even be possible to reach painless nursing;4)In active carbon fibre After the one layer of honey analgesic film of surface covering for tieing up layer, the adhesion of activated carbon fiber layers and wound surface can be reduced, so as to avoid The secondary damage of wound is brought during dressing to patient.
Embodiment
The present invention is described further with reference to embodiment;Following embodiments are only used for clearly illustrating this hair Bright object, technical solution and advantage, can not be limited the scope of the invention with this.
Embodiment 1:
A kind of activated carbon fibre dressing with pain-relieving functions, the dressing include activated carbon fiber layers, electret layer, pressure-sensitive viscous Paste layer and the honey analgesic film positioned at activated carbon fibre layer surface, and electret is located at activated carbon fiber layers and pressure sensitive adhesive layer Between, the electret layer is process by polytetrafluoroethylene film through ion build up process, the activated carbon fiber layers energy Electret layer is completely covered.Its specific preparation process is as follows:
(1)Component weighs 10 parts of aloe, 8 parts of fish pelargonium, 12 parts of rose extract, 20 parts of grape pip powder by weight, cleans and pulverizes, It is placed into volatile oil extractor, adds the water of 7 times of weight, put and be slowly heated to seethe with excitement in electric jacket, keep 4h, stops heating plate Carve, collect volatile oil a;
(2)200 parts of 58 parts of honey, 40 parts of glycerine, 6 parts of allantoin, 3 parts of citric acid and pure water are weighed by weight, heating is boiled, Filtering and concentrating obtains medicinal extract b;
(3)The surface of activated carbon fibre is modified:By FeCl of the medicinal active Carbon fibe through mass fraction 10%3Solution impregnates 60min;
(4)Volatile oil a and medicinal extract b are placed in reactor, are sufficiently mixed simultaneously heated at constant temperature, the activated carbon that above-mentioned surface is modified Fiber impregnation is in wherein, and dip time 20min, the thickness for making the honey analgesic film of activated carbon fibre area load is 30 μm, Then it is freeze-dried, then it is successively that the activated carbon fibre is for composite by layer of structure with electret, pressure sensitive adhesive layer, most pass through afterwards Irradiation sterilization after independent packaging to obtain the final product.
Embodiment 2:
A kind of activated carbon fibre dressing with pain-relieving functions, the dressing include activated carbon fiber layers, electret layer, pressure-sensitive viscous Paste layer and the honey analgesic film that surface is eaten positioned at activated carbon fibre, and electret layer is located at activated carbon fiber layers and pressure sensitive adhesive Between layer, the electret layer is process by polytetrafluoroethylene film through ion build up process, the activated carbon fiber layers Electret layer can be completely covered.Its specific preparation process is as follows:
(1)Component weighs 15 parts of aloe, 5 parts of fish pelargonium, 18 parts of rose extract, 25 parts of grape pip powder by weight, cleans and pulverizes, It is placed into volatile oil extractor, adds the water of 5 times of weight, put and be slowly heated to seethe with excitement in electric jacket, keep 5h, stops heating plate Carve, collect volatile oil a;
(2)250 parts of 50 parts of honey, 45 parts of glycerine, 3 parts of allantoin, 1 part of citric acid and pure water are weighed by weight, heating is boiled, Filtering and concentrating obtains medicinal extract b;
(3)The surface of activated carbon fibre is modified:By FeCl of the medicinal active Carbon fibe through mass fraction 1%3Solution impregnates 80min;
(4)Volatile oil a and medicinal extract b are placed in reactor, are sufficiently mixed simultaneously heated at constant temperature, the activated carbon that above-mentioned surface is modified Fiber impregnation is in wherein, and dip time 25min, the thickness for making the honey analgesic film of activated carbon fibre area load is 25 μm, Then it is freeze-dried, then it is successively that the activated carbon fibre is for composite by layer of structure with electret, pressure sensitive adhesive layer, most pass through afterwards Irradiation sterilization after independent packaging to obtain the final product.
Embodiment 3:
A kind of activated carbon fibre dressing with pain-relieving functions, the dressing include activated carbon fiber layers, electret layer, pressure-sensitive viscous Paste layer and the honey analgesic film positioned at activated carbon fibre layer surface, and electret layer is located at activated carbon fiber layers and pressure sensitive adhesive Between layer, the electret layer is process by polytetrafluoroethylene film through ion build up process, the activated carbon fiber layers Electret layer can be completely covered.Its specific preparation process is as follows:
(1)Component weighs 18 parts of aloe, 10 parts of fish pelargonium, 15 parts of rose extract, 30 parts of grape pip powder by weight, cleans and grinds It is broken, it is placed into volatile oil extractor, adds the water of 10 times of weight, put and be slowly heated to seethe with excitement in electric jacket, keep 8h, stops adding Backing is carved, and collects volatile oil a;
(2)220 parts of 60 parts of honey, 50 parts of glycerine, 7 parts of allantoin, 4 parts of citric acid and pure water are weighed by weight, heating is boiled, Filtering and concentrating obtains medicinal extract b;
(3)The surface of activated carbon fibre is modified:By FeCl of the medicinal active Carbon fibe through mass fraction 20%3Solution impregnates 100min;
(4)Volatile oil a and medicinal extract b are placed in reactor, are sufficiently mixed simultaneously heated at constant temperature, the activated carbon that above-mentioned surface is modified Fiber impregnation is in wherein, and dip time 15min, the thickness for making the honey analgesic film of activated carbon fibre area load is 50 μm, Then it is freeze-dried, then it is successively that the activated carbon fibre is for composite by layer of structure with electret, pressure sensitive adhesive layer, most pass through afterwards Irradiation sterilization after independent packaging to obtain the final product.
Embodiment 4:
A kind of activated carbon fibre dressing with pain-relieving functions, the dressing include activated carbon fiber layers, electret layer, pressure-sensitive viscous Paste layer and the honey analgesic film positioned at activated carbon fibre layer surface, and electret layer is located at activated carbon fiber layers and pressure sensitive adhesive Between layer, the electret layer is process by polytetrafluoroethylene film through ion build up process, the activated carbon fiber layers Electret layer can be completely covered.Its specific preparation process is as follows:
(1)Component weighs 20 parts of aloe, 6 parts of fish pelargonium, 16 parts of rose extract, 22 parts of grape pip powder by weight, cleans and pulverizes, It is placed into volatile oil extractor, adds the water of 8 times of weight, put and be slowly heated to seethe with excitement in electric jacket, keep 6h, stops heating plate Carve, collect volatile oil a;
(2)240 parts of 55 parts of honey, 48 parts of glycerine, 5 parts of allantoin, 5 parts of citric acid and pure water are weighed by weight, heating is boiled, Filtering and concentrating obtains medicinal extract b;
(3)The surface of activated carbon fibre is modified:By FeCl of the medicinal active Carbon fibe through mass fraction 15%3Solution impregnates 120min;
(4)Volatile oil a and medicinal extract b are placed in reactor, are sufficiently mixed simultaneously heated at constant temperature, the activated carbon that above-mentioned surface is modified Fiber impregnation is in wherein, and dip time 30min, the thickness for making the honey analgesic film of activated carbon fibre area load is 40 μm, Then it is freeze-dried, then it is successively that the activated carbon fibre is for composite by layer of structure with electret, pressure sensitive adhesive layer, most pass through afterwards Irradiation sterilization after independent packaging to obtain the final product.
Embodiment 5:Analgesic effect
The pain patients that any dressing obtained by by embodiment 1 ~ 4 frustrates damage to 196 different joint parts are treated, 1 month 1 course for the treatment of, treats 1 ~ 2 course for the treatment of, cures 155, accounts for 79.1%;Effective 32, account for 16.3%;Effective 9, account for 4.59%;Invalid 0.Diseased region is referred to shown in following table with curative effect situation.Clinical test shows, treats each joint part bruise Damage is produced effects soon, and curative effect is relatively consolidated, and through follow-up, its long-term effect is preferable;By the dressing of the present invention, i.e., in the quiet of electret Under the synergy of electron ion induction effect and honey, the clinical symptoms of each joint part of patient can be obviously improved, improve god The microcirculation of lesion local organization through root myelopathy patient, promotes inflammation to absorb, and alleviates muscle spasmus;Can be by improving blood Pressure, promotes blood circulation unobstructed, reaches analgesic effect.
Therapeutic effect of 1 dressing of table to each joint part pain
Joint part Case Cure It is effective Effectively It is invalid Effective percentage/%
Shoulder joint 52 32 18 2 0 100
Hip joint 68 54 10 4 0 100
Knee joint 65 60 2 3 0 100
Ankle-joint 11 9 2 0 0 100
It is total 196 155 32 9 0 100
Experimental example 6:Animal experiment
Male New Zealand rabbits are taken, 72, every 2 ~ 3kg, are randomly divided into six groups, every group 12.Each rabbit is according to clinical animal Experimental burning master pattern preparation method causes the shallow II degree damages of 30%TBSA, and wherein A groups rabbit is without using any dressing, B groups Rabbit application cotton balls containing Iodophor, the composite fluid dressing of C, D, E, F group application embodiment of the present invention 1 ~ 4, is replaced twice, directly daily Wound healing to C, D, E, F group just terminates this zoopery.
From the result of zoopery, after the respective dressing of C ~ F group rabbit surface of a wound application, the surface of a wound without infection phenomenons, Occur without redness.And from healing time, the healing time of C ~ F group rabbit surface of a wound is considerably less than B groups, and time difference has aobvious Meaning is write, is shown in Table 2:
2 each group animal trauma surface infestation of table and healing state (%)
Group Wound infection rate (%) 7d healing rates (%) Healing time (d)
A groups 100 It is red and swollen It is red and swollen after 15d gradually to move back, start to form a scab
B groups 0 It is slight red and swollen 16.8±2.2
C groups 0 75.7±2.4 9.4±1.8
D groups 0 73.9±2.1 11.5±1.9
E groups 0 72.0±1.8 12.1±2.3
F groups 0 76.5±2.6 11.9±2.0
From the whole result of six groups of experiments, the healing of the dressing of Iodophor cotton balls and the dressing of the invention prepared to the surface of a wound can be played The effect of acceleration, and the dressing of C ~ F groups is because containing the functional component such as antibacterial, anti-inflammatory and analgesic and absorption sepage, in the work of moisturizer With lower effective nuring wound, the microenvironment of surface of a wound part is significantly improved, wound healing simultaneously shortens healing time.

Claims (6)

1. a kind of activated carbon fibre dressing with pain-relieving functions, it is characterised in that including peel ply, activated carbon fiber layers and pressure Quick adhered layer, is equipped with electret layer between the activated carbon fiber layers and the pressure sensitive adhesive layer, the activated carbon fiber layers Surface relieves pain film covered with one layer of honey, and honey analgesic film includes the raw material of following parts by weight:It is 50-60 parts of honey, sweet 40-50 parts oily, 3-7 parts of allantoin, 1-5 parts of citric acid, 200-250 parts of pure water, 10-20 parts of aloe, 5-10 parts of fish pelargonium, rose Rare extract 12-18 parts, 20-30 parts of grape pip powder.
2. the activated carbon fibre dressing according to claim 1 with pain-relieving functions, it is characterised in that the electret Layer is process by polytetrafluoroethylene film through ion build up process.
3. the activated carbon fibre dressing according to claim 1 with pain-relieving functions, it is characterised in that the activated carbon The electret layer can be completely covered for fibrous layer.
4. the preparation method of any activated carbon fibre dressing with pain-relieving functions of claims 1 to 3, its feature exist In, including following specific steps:
(1)Aloe, fish pelargonium, rose extract, grape pip powder are weighed by weight, are cleaned and are pulverized, are placed into volatile oil extractor In, add the water of 5-10 times of weight, put and be slowly heated to seethe with excitement in electric jacket, keep 4 ~ 8h, stop heating a moment, collect volatile oil a;
(2)Honey, glycerine, allantoin, citric acid and pure water are weighed by weight, and heating is boiled, and filtering and concentrating obtains medicinal extract b;
(3)The surface of activated carbon fibre is modified:By FeCl of the activated carbon fibre through mass fraction 1 ~ 20%3Solution dipping 60 ~ 120min;
(4)Volatile oil a and medicinal extract b are placed in reactor, are sufficiently mixed simultaneously heated at constant temperature, will be through step(3)Modified activity Carbon fibe is impregnated in wherein, is then freeze-dried, then the activated carbon fibre and electret, pressure sensitive adhesive layer are pressed structure sheaf successively Secondary for composite, most irradiation sterilization after independent packaging afterwards to obtain the final product.
5. the preparation method of the activated carbon fibre dressing according to claim 4 with pain-relieving functions, it is characterised in that institute The step of stating(4)In heating-up temperature be 80 ~ 120 DEG C.
6. the preparation method of the activated carbon fibre dressing according to claim 4 with pain-relieving functions, it is characterised in that institute The step of stating(4)In dip time be 15 ~ 30min, in obtained dressing activated carbon fibre area load honey analgesic film Thickness be 25 ~ 50 μm.
CN201711356276.3A 2017-12-16 2017-12-16 A kind of activated carbon fibre dressing with pain-relieving functions and preparation method thereof Pending CN107929792A (en)

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Citations (3)

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Application publication date: 20180420