CN107929663A - A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach - Google Patents
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach Download PDFInfo
- Publication number
- CN107929663A CN107929663A CN201711117364.8A CN201711117364A CN107929663A CN 107929663 A CN107929663 A CN 107929663A CN 201711117364 A CN201711117364 A CN 201711117364A CN 107929663 A CN107929663 A CN 107929663A
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- stomach
- chinese medicine
- chinese
- medicine composition
- early carcinoma
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Abstract
The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of Chinese medicine composition that can effectively treat early carcinoma of stomach according to the understanding mechanism of Chinese traditional treatment early carcinoma of stomach, each component and its mass parts ratio of the Chinese medicine composition are as follows：100~350g of coix seed, 100~160g of root of Chinese trichosanthes, 30~150g of Ligusticum wallichii, 15~70g of indigo naturalis, 100~160g of Radix Paeoniae Alba, 30~120g of Asian puccoon, 30~150g of rheum officinale, 60~160g of Divine Comedy, 60~120g of peach kernel, 30~120g of safflower, 30~120g of curcuma zedoary, 30~100g of aspongopus, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~90g of bush, 15~40g of leech, 90~160g of dalbergia wood, 60~150g of pig Poria cocos；Medicine provided by the invention is a good Chinese prescription.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is special
It is not the field of the Chinese medicine composition used for early carcinoma of stomach patient.
Background technology
Shown according to related data：Stomach cancer ranks first in the various malignant tumours in China, and incidence gastric cancer has obvious region
Difference, is evident as with coastal region in east China incidence gastric cancer rate high in the northwest in China than southern area.Well send out the age 50 years old with
On, the ratio between men and women's incidence is 2：1.The prognosis of stomach cancer and the pathological staging of stomach cancer, position, organization type, biological behaviour with
And remedy measures are related.
Clinical manifestation：Early carcinoma of stomach majority patient's non-evident sympton, a few peoples have Nausea and vomiting or similar to cankers
Digestive symptoms.Pain and weight loss are the most common clinical symptoms of advanced gastric carcinoma.Patient Chang You more clearly on
Symptom of digestive tract, it is loss of appetite, weak as disease progression Upper abdominal pain aggravates such as glutted after epigastric discomfort, feed.According to
The position of tumour is different, also there is its Special Manifestations.Orifice of the stomach stomach bottom cancer can have retrosternal pain and progressive dysphagia；Pylorus is attached
Near stomach cancer has pyloric stenosis performance；There can be the hemorrhage of digestive tract symptom such as spitting blood, melena after tumor destruction blood vessel.Belly persistently aches
Often prompting expanding tumor exceeds stomach wall to pain, lays one's hand on and swells as recessed before supraclavicular lymph nodes enlargement, ascites, jaundice, abdominal mass, rectum
Block etc..Late gastric cancer patient often may occur in which anaemia, become thin, malnutritive even cachexia etc. performance.The diffusion and transfer of stomach cancer
There is following approach：
A. direct invasion
Orifice of the stomach stomach bottom cancer is easily invaded and lower esophagus, gastric cancer can be infiltrated to duodenum.The stomach cancer of the poor infiltrative growth of differentiation is dashed forward
After broken serous coat, the adjacent organs such as nethike embrane, colon, liver, pancreas are easily diffused to.
B. hematogenous metastasis
Occur late, cancer cell enters portal vein or body circulation is sent out at other positions to body, forms transfer stove.Common transfer
Organ have liver, lung, pancreas, bone etc., be more using hepatic metastases.
C. peritoneal implantation metastasis
After stomach organization is infiltrated to outside serous coat, tumour cell comes off and is planted on peritonaeum and internal organs serous coat, forms transfer knot
Section.Recessed metastatic carcinoma, digital rectal examination are can be found that before rectum.Metastatic tumor of ovary can occur for female patients stomach cancer.
D. Lymph Node Metastasis
It is the main route of metastasis of stomach cancer, the Lymph Node Metastasis rate of advanced gastric carcinoma is up to 70% or so, and early carcinoma of stomach can also have lymph
Transfer.The rate of lymph-node metastasis of stomach cancer and the invasive depth of cancer stove are proportionate.The lymphatic metastasis of stomach cancer it is typically sequential by
Walk progressive, but great-jump-forward Lymph Node Metastasis, i.e. first stop can also occur without transfer and second station has transfer.Whole latter stage stomach cancer can be through chest
Supraclavicular lymph nodes shifts conduit to the left, or is transferred to umbilical region through ligamentum teres hepatis.
So, just how to find a kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, be those skilled in the art urgently
The problem of to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment early carcinoma of stomach, people gradually appreciate middle treatment
The advantages for the treatment of early carcinoma of stomach, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, control for existing doctor trained in Western medicine
The present situation of early carcinoma of stomach is treated, the purpose of the invention is to provide a kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, with
Solve the problems, such as that early carcinoma of stomach patient gets well and extend life cycle early.The medicine is using common Chinese medicine as raw material, is led to
Cross and select rational medicine and mass parts ratio, can effectively treat above-mentioned early carcinoma of stomach one and demonstrate,prove.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：Early stage can effectively be treated by providing one kind
The Chinese medicine composition of stomach cancer, it is characterised in that each component and mass parts of the Chinese medicine composition are than as follows：
100~350g of coix seed, 100~160g of root of Chinese trichosanthes, 30~150g of Ligusticum wallichii, 15~70g of indigo naturalis, 100~160g of Radix Paeoniae Alba, purple
30~120g of grass, 30~150g of rheum officinale, 60~160g of Divine Comedy, 60~120g of peach kernel, 30~120g of safflower, 30~120g of curcuma zedoary,
30~100g of aspongopus, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~90g of bush, 15~40g of leech, 90~160g of dalbergia wood, pig Poria cocos 60~
150g, auxiliary material：Appropriate starch.
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that each group of the Chinese medicine composition
Divide and mass parts are than as follows：
115~310g of coix seed, 115~140g of root of Chinese trichosanthes, 38~130g of Ligusticum wallichii, 20~60g of indigo naturalis, 115~140g of Radix Paeoniae Alba, purple
38~105g of grass, 38~130g of rheum officinale, 70~140g of Divine Comedy, 70~105g of peach kernel, 38~105g of safflower, 38~105g of curcuma zedoary,
38~90g of aspongopus, 58~140g of Rhizoma Atractylodis Macrocephalae, 38~80g of bush, 18~35g of leech, 100~140g of dalbergia wood, pig Poria cocos 70~
130g, auxiliary material：Appropriate starch.
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that each group of the Chinese medicine composition
Divide and mass parts are than as follows：
Coix seed 280g, root of Chinese trichosanthes 120g, Ligusticum wallichii 115g, indigo naturalis 52g, Radix Paeoniae Alba 120g, Asian puccoon 95g, rheum officinale 115g, Divine Comedy
120g, peach kernel 95g, safflower 95g, curcuma zedoary 95g, aspongopus 80g, Rhizoma Atractylodis Macrocephalae 120g, bush 70g, leech 31g, dalbergia wood 120g, pig Fu
Siberian cocklebur 118g, auxiliary material：Appropriate starch.
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that system that described method includes following steps
It is standby to form：
A, except indigo naturalis（Separately it is ground into superfine end）Outside, after above-mentioned other raw material Chinese medicines being picked impurity and dust, according to mass parts ratio
Coarse is respectively crushed into decoct a drug wrapped；
B, the raw material Chinese medicine wrapped is put into after soaking 40min in cold boiling water, then soaked medicine is put into marmite and is decocted
Three times：1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when 15min is arrived in decoction, turns slow boiling and boils 115
Min, leaching liquid；2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, when 10min is arrived in decoction, is turned
Slow boiling boils 105 min, leaching liquid；3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct
During to 8min, turn slow boiling and boil 90 min, leaching liquid；4. merging liquid three times, and it is concentrated under reduced pressure into every milliliter contained 3g
Standard after, that is, obtain drug extract.
C, by the extract dry prepared in above-mentioned B, disinfection, and it is spare according to mass parts ratio to be ground into superfine end；
D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh ground in A and C
After thing sieving, and auxiliary material is put into medicine device and is uniformly mixed in the lump, is then prepared into capsule（Total length after its capsule is sealed is
23.3mm, medicinal powder capacity 0.4~0.5g/）, then polish, sterilize, sealed packaging.
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that the instructions of taking is：It will prepare
Capsule medicine three times a day to take, once a dose in the morning, afternoon and evening, dosage 2.4g（6）/ time, warm water delivery service.30 days
As a treatment course, after 6~7 courses for the treatment of of taking medicine, sign and symptom are improved, and lesion disappears substantially.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine
Carry.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：
Coix seed, nature and flavor：It is sweet, light, be slightly cold, have clearing damp and promoting diuresis, invigorating the spleen to arrest diarrhea, clearing damp eliminating impediment, clearing away heat and eliminating pus the effect of, be used for
Treat the diseases such as difficult urination, oedema, tinea pedis, splenasthenic diarrhea, arthralgia pain due to rheumatism, Spasm of the tendons, lung carbuncle, acute appendicitis；
Root of Chinese trichosanthes, nature and flavor：Bitter, micro-sweet, has the effect of clearing heat and promoting fluid, detumescence and apocenosis, for treating pyreticosis Tianjin wound, dry, disappearing
Yearningly, cough with lung heat, dryness of the lung hemoptysis, heat toxin sore carbuncle；
Ligusticum wallichii, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating menstruation not
The stagnant raw meat pain of tune, closed dysmenorrhea, the postpartum stasis of blood, abdominal mass lump, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sore
Ulcer；
Indigo naturalis, nature and flavor：Taste is salty, cold in nature, has the effect of clearing heat and detoxicating, cooling blood and hemostasis, clearing liver-fire, for treating warm disease heat toxin
Macula, blood-head haematemesis, bleeding from five sense organs or subcutaneous tissue, spitting of blood, the hot frightened epilepsy of liver, liver-fire attacking lung cough, abscess of throat, erysipelas, Zha, sore swells, snakebite and bugbite；
Radix Paeoniae Alba, nature and flavor：Bitter, acid, be slightly cold, and has the effect of cloudy, soft liver analgesic, suppressing liver-YANG are held back in blood-nourishing, for treating menstruation not
Tune, uterine bleeding, abnormal sweating, gastral cavity abdomen shoot, pain over the hypochondriac region, four limbs contraction pain, dizziness of having a headache；
Asian puccoon, nature and flavor：It is sweet, cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, removing toxic substances, promoting eruption, for treating maculopapulae due to toxic heat, heat toxin sore
Ulcer；
Rheum officinale, nature and flavor：It is bitter, cold, there is the effect of heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, promoting blood circulation, for treating intestines
Road stagnates, constipation, blood-head tells nosebleed, hot eyes, pharyngalgia, swelling and aching of gum, pathopyretic ulcer, scald, blood stasis, bruise damage
The diseases such as wound, jaundice with damp-heat pathogen, heat gonorrhea；
Divine Comedy, nature and flavor：It is sweet, pungent, warm, there is the effect of helping digestion with stomach, antidiarrheal inducing diaphoresis, for treating indigestion, abdominal fullness and distention
And the gastrointestinal symptom caused by flu；
Peach kernel, nature and flavor：It is bitter, flat, there is promoting blood circulation, the effect of relaxing bowel, for treating Amenorrhea, dysmenorrhoea, postpartum stasis, falling
Injure pain, lung carbuncle, acute appendicitis, dry constipation of intestines；
Safflower, nature and flavor：It is pungent, warm, there is the effect of promoting blood circulation and removing blood stasis, promoting menstruation, for treating amenorrhea due to stagnation of blood, postpartum stasis, Disorder lumps in the abdomen product
Stagnant, injuries from falls as well, measles without adequate eruption；
Curcuma zedoary, nature and flavor：Toil, temperature, have the effect of blood-breaking, Xiao Ji Zhi Tong, for treat pained vim and vigour, eating accumulation,
Abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury, be additionally operable to abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain,
Accumulation, abdominal mass lump, women's blood stasis, traumatic injury are had a pain eating accumulation, and it is antitumor that modern pharmacology shows that oriental wormwood has
Effect：Its aromatic turmeric oil preparation is in vitro to the L615 leukaemia and ascitic type of Mouse Ehrlich Carcinoma Cells, 615 mouse inbred lines
The growth of a variety of knurl strains such as liver cancer cells has obvious suppression and destruction.Clinic makees intratumoral injection uterine neck with oil of zedoary turmeric
Cancer, after treatment visible tumor tissue necrosis come off, local lymphocytes infiltration, some cases lump disappear, uterine neck is smooth, prompt cowherb
Art plays the role of directly killing oncocyte；
Aspongopus, nature and flavor：Taste is salty, warm-natured, has the effect of promoting qi circulation and relieving pain, warming kidney and enhancing body, for treating the insufficiency of the spleen stagnation of the circulation of vital energy, chest gastral cavity ruffian
The diseases such as vexed, pain, kidney yang deficiency, soreness of waist and knee joint, impotence frequent micturition；
Rhizoma Atractylodis Macrocephalae, nature and flavor：It is bitter, sweet, warm, there is the effect of air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating Spleen-Qi Deficiency
The diseases such as weak, anorexia and loose stool, phlegm and retained fluid oedema, exterior deficiency spontaneous perspiration, fetal irritability；
Bush, nature and flavor：It is sweet, salty, flat, have promoting blood circulation, swelling and pain relieving the effect of, for treat traumatic injury, fracture the injury of tendon and muscle,
The stagnant swelling and pain of the stasis of blood, closed dysmenorrhea, postpartum stasis, chest and abdomen shouting pain, ulcer sore pain；
Leech, nature and flavor：It is salty, bitter, flat, have blood-breaking promoting menstruation, by stagnation resolvation disease the effect of, for treat blood stasis, addiction lump in the abdomen lump in the abdomen,
Hemiplegia, injury from falling down；
Dalbergia wood, nature and flavor：It is pungent, warm, there is the effect of removing blood stasis and hemostasis, regulating qi-flowing for relieving pain, for treating haematemesis, bleeding from five sense organs or subcutaneous tissue, traumatic hemorrhage, liver
The diseases such as strongly fragrant hypochondriac pain, obstruction of qi in the chest shouting pain, the pain of injury caused by falling and tumbling, vomiting abdominal pain；
Pig Poria cocos, nature and flavor：It is sweet in flavor, light, mild-natured, have can diuresis, anticancer, antitumor, clearing damp and promoting diuresis the effect of, it is small for treating
Just unfavorable, oedema, diarrhea, stranguria with turbid discharge, band under, malignant tumour, acute leukemia psoriasis.
Medicine of the present invention is the principle based on Chinese traditional treatment early carcinoma of stomach, from the pathomechanism and pharmacology according to early carcinoma of stomach
Effect is thought：With regard to early carcinoma of stomach, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease
Therapeutic effect.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned early carcinoma of stomach, is prepared using the formula
Medicine effect is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific of the present invention
Embodiment is described in further detail：
Embodiment 1：
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that each component of the Chinese medicine composition and
Mass parts are than as follows：
Coix seed 280g, root of Chinese trichosanthes 120g, Ligusticum wallichii 115g, indigo naturalis 52g, Radix Paeoniae Alba 120g, Asian puccoon 95g, rheum officinale 115g, Divine Comedy
120g, peach kernel 95g, safflower 95g, curcuma zedoary 95g, aspongopus 80g, Rhizoma Atractylodis Macrocephalae 120g, bush 70g, leech 31g, dalbergia wood 120g, pig Fu
Siberian cocklebur 118g, auxiliary material：Appropriate starch.
Embodiment 2：
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that each component of the Chinese medicine composition and
Mass parts are than as follows：
Coix seed 310g, root of Chinese trichosanthes 140g, Ligusticum wallichii 130g, indigo naturalis 60g, Radix Paeoniae Alba 140g, Asian puccoon 105g, rheum officinale 130g, Divine Comedy
140g, peach kernel 105g, safflower 105g, curcuma zedoary 105g, aspongopus 90g, Rhizoma Atractylodis Macrocephalae 140g, bush 80g, leech 35g, dalbergia wood 140g,
Pig Poria cocos 130g, auxiliary material：Appropriate starch.
Embodiment 3：
A kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that each component of the Chinese medicine composition and
Mass parts are than as follows：
Coix seed 350g, root of Chinese trichosanthes 160g, Ligusticum wallichii 150g, indigo naturalis 70g, Radix Paeoniae Alba 160g, Asian puccoon 120g, rheum officinale 150g, Divine Comedy
160g, peach kernel 120g, safflower 120g, curcuma zedoary 120g, aspongopus 100g, Rhizoma Atractylodis Macrocephalae 160g, bush 90g, leech 40g, dalbergia wood 160g,
Pig Poria cocos 150g, auxiliary material：Appropriate starch.
Model case：
Through clinical conditions patients with gastric cancer totally 1345, the age is 769 of over-65s, and only 576 are less than 65 years old.
Fully recovering in 1345 patients and extending life cycle has 434, effective 642, invalid 269.Total effective rate is up to 80%.
Claims (3)
- A kind of 1. Chinese medicine composition that can effectively treat early carcinoma of stomach, it is characterised in that each component of the Chinese medicine composition And its mass parts are than as follows：100~350g of coix seed, 100~160g of root of Chinese trichosanthes, 30~150g of Ligusticum wallichii, 15~70g of indigo naturalis, 100~160g of Radix Paeoniae Alba, purple 30~120g of grass, 30~150g of rheum officinale, 60~160g of Divine Comedy, 60~120g of peach kernel, 30~120g of safflower, 30~120g of curcuma zedoary, 30~100g of aspongopus, 50~160g of Rhizoma Atractylodis Macrocephalae, 30~90g of bush, 15~40g of leech, 90~160g of dalbergia wood, pig Poria cocos 60~ 150g, auxiliary material：Appropriate starch.
- 2. the Chinese medicine composition according to claim 1 that can effectively treat early carcinoma of stomach, it is characterised in that the Chinese medicine group The each component and its mass parts of compound are than as follows：115~310g of coix seed, 115~140g of root of Chinese trichosanthes, 38~130g of Ligusticum wallichii, 20~60g of indigo naturalis, 115~140g of Radix Paeoniae Alba, purple 38~105g of grass, 38~130g of rheum officinale, 70~140g of Divine Comedy, 70~105g of peach kernel, 38~105g of safflower, 38~105g of curcuma zedoary, 38~90g of aspongopus, 58~140g of Rhizoma Atractylodis Macrocephalae, 38~80g of bush, 18~35g of leech, 100~140g of dalbergia wood, pig Poria cocos 70~ 130g, auxiliary material：Appropriate starch.
- 3. the Chinese medicine composition that can effectively treat early carcinoma of stomach according to claim 1 to 2, it is characterised in that in described The each component and its mass parts of drug composition are than as follows：Coix seed 280g, root of Chinese trichosanthes 120g, Ligusticum wallichii 115g, indigo naturalis 52g, Radix Paeoniae Alba 120g, Asian puccoon 95g, rheum officinale 115g, Divine Comedy 120g, peach kernel 95g, safflower 95g, curcuma zedoary 95g, aspongopus 80g, Rhizoma Atractylodis Macrocephalae 120g, bush 70g, leech 31g, dalbergia wood 120g, pig Fu Siberian cocklebur 118g, auxiliary material：Appropriate starch.
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