CN107854642A - A kind of pill medicine for treating early carcinoma of stomach and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of pill medicine for treating early carcinoma of stomach according to the understanding mechanism of Chinese traditional treatment early carcinoma of stomach, each component and its mass parts ratio of the medicine are as follows：50~160g of Radix Angelicae Sinensis, 100~160g of Poria cocos, 60~120g of dried orange peel, 60~150g of rhizoma cyperi, 30~120g of the banksia rose, 30~120g of subprostrate sophora, 30~100g of monkshood, 100~360g of prepared rhizome of rehmannia, 100~160g of malt, 30~120g of Rhizoma Sparganii, 15~90g of ginseng, 30~100g of ground bettle, 50~90g of grass-leaved sweetflag, 30~100g of pangolin, 3~10g of storax, 10~30g of agalloch eaglewood, 60~160g of Semen Nelumbinis；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of pill medicine for treating early carcinoma of stomach and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating early carcinoma of stomach, particularly for early The field of the pill medicine that phase patients with gastric cancer uses and preparation method thereof.

Background technology

Shown according to related data：Stomach cancer ranks first in the various malignant tumours in China, and incidence gastric cancer has obvious region Difference, it is evident as in the northwest in China than southern area with coastal region in east China incidence gastric cancer rate high.Well send out the age 50 years old with On, the ratio between men and women's incidence of disease is 2：1.The prognosis of stomach cancer and the pathological staging of stomach cancer, position, organization type, biological behaviour with And remedy measures are relevant.

Clinical manifestation：Early carcinoma of stomach majority patient's non-evident sympton, a few peoples have Nausea and vomiting or similar to cankers Digestive symptoms.Pain and weight loss are the most common clinical symptoms of advanced gastric carcinoma.Patient Chang You more clearly on Symptom of digestive tract, it is loss of appetite, weak as disease progression Upper abdominal pain aggravates such as glutted after epigastric discomfort, feed.According to The position of tumour is different, also there is its Special Manifestations.Orifice of the stomach stomach bottom cancer can have retrosternal pain and progressive dysphagia；Pylorus is attached Near stomach cancer has pyloric stenosis performance；There can be the hemorrhage of digestive tract symptom such as spitting blood, melena after tumor destruction blood vessel.Belly persistently aches Often prompting expanding tumor exceeds coat of the stomach to pain, lays one's hand on and swells as recessed before supraclavicular lymph nodes enlargement, ascites, jaundice, abdominal mass, rectum Block etc..Late gastric cancer patient often may occur in which anaemia, become thin, malnutritive even cachexia etc. performance.The diffusion and transfer of stomach cancer There is following approach：

A. direct invasion

Orifice of the stomach stomach bottom cancer is easily invaded and lower esophagus, gastric cancer can infiltrate to duodenum.The stomach cancer for breaking up poor infiltrative growth is dashed forward After broken serous coat, the adjacent organs such as nethike embrane, colon, liver, pancreas are easily diffused to.

B. hematogenous metastasis

Occur late, cancer cell enters portal vein or body circulation is sent out at other positions to body, forms transfer stove.Common transfer Organ have liver, lung, pancreas, bone etc., be more using hepatic metastases.

C. peritoneal implantation metastasis

After stomach organization is infiltrated to outside serous coat, tumour cell comes off and is planted on peritonaeum and internal organs serous coat, forms transfer knot Section.Recessed metastatic carcinoma, digital rectal examination are can be found that before rectum.Metastatic tumor of ovary can occur for female patients stomach cancer.

D. Lymph Node Metastasis

It is the main route of metastasis of stomach cancer, the Lymph Node Metastasis rate of advanced gastric carcinoma is up to 70% or so, and early carcinoma of stomach can also have lymph Transfer.The rate of lymph-node metastasis of stomach cancer and the invasive depth of cancer stove are proportionate.The lymphatic metastasis of stomach cancer it is typically sequential by Walk progressive, but great-jump-forward Lymph Node Metastasis, i.e. first stop can also occur without transfer and second station has transfer.Whole latter stage stomach cancer can be through chest Supraclavicular lymph nodes shifts conduit to the left, or is transferred to umbilical region through ligamentum teres hepatis.

So, just how to find a kind of Chinese medicine composition that can effectively treat early carcinoma of stomach, be those skilled in the art urgently The problem of to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment early carcinoma of stomach, people gradually appreciate middle treatment The advantages for the treatment of early carcinoma of stomach, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, control for existing doctor trained in Western medicine The present situation of early carcinoma of stomach is treated, the purpose of the present invention is to be to provide a kind of pill medicine for treating early carcinoma of stomach, to solve early stage The problem of patients with gastric cancer is got well and extends life cycle early.The medicine is using common Chinese medicine as raw material, by selecting to close Medicine and the mass parts ratio of reason, can effectively treat above-mentioned early carcinoma of stomach.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of early carcinoma of stomach for the treatment of is provided Pill medicine and preparation method thereof, it is characterised in that each component and mass parts of the medicine are than as follows：

50~160g of Radix Angelicae Sinensis, 100~160g of Poria cocos, 60~120g of dried orange peel, 60~150g of rhizoma cyperi, 30~120g of the banksia rose, subprostrate sophora 30~120g, 30~100g of monkshood, 100~360g of prepared rhizome of rehmannia, 100~160g of malt, 30~120g of Rhizoma Sparganii, 15~90g of ginseng, 30~100g of ground bettle, 50~90g of grass-leaved sweetflag, 30~100g of pangolin, 3~10g of storax, 10~30g of agalloch eaglewood, Semen Nelumbinis 60~160g, auxiliary material：Appropriate starch.

A kind of pill medicine for treating early carcinoma of stomach and preparation method thereof, it is characterised in that each component of the medicine And mass parts are than as follows：

58~140g of Radix Angelicae Sinensis, 115~140g of Poria cocos, 70~105g of dried orange peel, 70~130g of rhizoma cyperi, 38~105g of the banksia rose, subprostrate sophora 38~105g, 38~90g of monkshood, 115~320g of prepared rhizome of rehmannia, 115~140g of malt, 38~105g of Rhizoma Sparganii, 20~80g of ginseng, 38~90g of ground bettle, 58~80g of grass-leaved sweetflag, 38~90g of pangolin, 5~9g of storax, 12~26g of agalloch eaglewood, Semen Nelumbinis 70~ 140g, auxiliary material：Appropriate starch.

A kind of pill medicine for treating early carcinoma of stomach and preparation method thereof, it is characterised in that each component of the medicine And mass parts are than as follows：

Radix Angelicae Sinensis 120g, Poria cocos 120g, dried orange peel 95g, rhizoma cyperi 118g, banksia rose 95g, subprostrate sophora 95g, monkshood 80g, prepared rhizome of rehmannia 260g, Malt 120g, Rhizoma Sparganii 95g, ginseng 70g, ground bettle 80g, grass-leaved sweetflag 70g, pangolin 80g, storax 8g, agalloch eaglewood 23g, lotus seeds Meat 120g, auxiliary material：Appropriate starch.

A kind of pill medicine for treating early carcinoma of stomach and preparation method thereof, it is characterised in that methods described includes following step Suddenly it is prepared：

A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With；

B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing is crossed into 100 mesh sieves, it is well mixed, Produce medicinal powder 1.；Then appropriate amount of starch is added in medicinal powder, is well mixed, is prepared into water-bindered pill agent 2., 3. and then is dried, sterilization, Sealed packaging.

A kind of pill medicine for treating early carcinoma of stomach and preparation method thereof, it is characterised in that the instructions of taking is：Will system The water pill medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 5g/ times, warm water delivery service.30 days are one The individual course for the treatment of, after 7~8 courses for the treatment of of taking medicine, sign and symptom are improved, and focus disappears substantially, and stool is normal.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Radix Angelicae Sinensis, nature and flavor：It is sweet, pungent, warm, there is promoting blood circulation and stopping pain, tonifying blood and regulating menstruation, the effect of relaxing bowel, for treat dizziness due to deficiency of blood, Irregular menstruation, Amenorrhea, dysmenorrhoea, sallow complexion, asthenia cold abdominalgia, traumatic injury, arthralgia pain due to rheumatism, ulcer sores, dry constipation of intestines；

Poria cocos, nature and flavor：It is sweet, light, flat, there is the effect of clearing damp and promoting diuresis, invigorating the spleen, calm the nerves, for treating oedema, diarrhea, urine not The diseases such as profit, phlegm and retained fluid, palpitaition, insomnia；

Dried orange peel, nature and flavor：It is acrid flavour, hardship, warm-natured, have qi-regulating and in, eliminating dampness and eliminating phlegm, sharp water defaecation the effect of, for treating taste Discord, abdominal distention, do not feel like eating, vomiting hiccup, phlegm-damp obstructing lung, coughing with a lot of sputum, the full vexed, vertigo of chest diaphragm, oedema, urine The diseases such as unfavorable, constipation, acute mastitis sore tinea, middle ichthyophagy crab poison, wine poison；

Rhizoma cyperi, nature and flavor：Pungent, slight bitter, micro-sweet, there is the effect of dispersing stagnated hepatoqi, menstruction regulating and pain relieving, for treating pain over the hypochondriac region, gastral cavity abdomen Distending pain, hernia pain, irregular menstruation, swollen breasts；

The banksia rose, nature and flavor：Acrid, bitter, warm, have promoting qi circulation and relieving pain, adjust in declare the effect of stagnant, for treat abdominal distention, weight after rush down dysentery, The diseases such as spleen eating less, hypochondriac pain, jaundice；

Subprostrate sophora, nature and flavor：It is bitter, cold, there is the effect of clearing heat and detoxicating, reducing pharyngeal swelling, for treat abscess of throat, cough with lung heat, Carbuncle sore tumefacting virus；

Monkshood, nature and flavor：Acrid flavour, hardship, property heat, effect：Dispelling wind and eliminating dampness, the effect of antalgic, for treating wind-cold-dampness arthralgia, closing Save pain, trusted subordinate's crymodynia, cold hernia is had a pain and narcotic analgesic；

Prepared rhizome of rehmannia, nature and flavor：Sweet, tepor, there is the effect of nourishing the blood and yin, enriching essence and nourishing marrow, for treating blood deficiency chlorosis, the dizziness heart Throb with fear, irregular menstruation, hectic fever night sweat, quench one's thirst, the disease such as soreness of waist tinnitus；

Malt, nature and flavor：It is sweet, flat, there is the effect of food digesting stomach fortifying, delaactation dissipate-swelling, it is swollen vexed, newborn for treating dyspepsia, gastral cavity abdomen The diseases such as juice smoulders, mastosis；

Rhizoma Sparganii, nature and flavor：It is bitter, flat, there is the effect of dissipating blood stasis with potent drugs, promoting qi circulation and relieving pain, for treating Amenorrhea stomachache, lumps in the chest and abdomen, food The diseases such as product stomachache；

Ginseng, nature and flavor：Sweet, slight bitter, temperature, there is invigorating qi for relieving desertion, tonifying lung benefit spleen, promote the production of body fluid, calm the nerves, the effect of intelligence development, for treating Tonifying Qi emergency treatment of collapse, Yixinfumai, calm the nerves, promote the production of body fluid, tonifying lung, the function such as invigorating the spleen, for treatment angiocardiopathy, stomach and liver diseases, Diabetes, different types of nervous breakdown, various mental diseases, impotence and some cancers etc. have good therapeutic effect, are also a kind of Strengthening by means of tonics medicine；

Ground bettle, nature and flavor：Taste is salty, cold in nature, has the effect of dissipating blood stasis with potent drugs, reunion of fractured tendons and bones, for treating traumatic injury, injury of tendon and muscle bone The diseases such as folding, blood stasis, postpartum stasis stomachache, addiction lump in the abdomen lump in the abdomen；

Grass-leaved sweetflag, nature and flavor：It is pungent, warm, have eliminating the phlegm have one's ideas straightened out, dampness elimination appetizing, allay excitement intelligence development the effect of, for treat divine coma, The disease such as palpitation with fear, insomnia, dull-witted, forgetful, chest and abdomen swelling and pain, wind-cold-dampness arthralgia, mange；

Pangolin, nature and flavor：It is salty, be slightly cold, have invigorate blood circulation, it is lower breast, detumescence and apocenosis the effect of, for treating Amenorrhea, Disorder lumps in the abdomen, breast The diseases such as juice is obstructed, arthralgia pain due to rheumatism, spasm of limbs, carbuncle swells, scrofula, subcutaneous nodule；

Storax, nature and flavor：It is sweet, warm, there is the effect of having one's ideas straightened out, eliminating the phlegm, for treating the diseases such as apoplexy coma due to blocking of the respiratory system, frightened epilepsy；

Agalloch eaglewood, nature and flavor：Pungent, bitter, tepor, have promoting qi circulation and relieving pain, warming middle energizer to arrest vomiting, warm kidney receive gas the effect of, it is swollen for treating chest and abdomen Bitterly, the diseases such as hiccup, syndrome characterized by dyspnea are vomitted；

Semen Nelumbinis, nature and flavor：It is sweet, puckery, flat, there is the effect of tonifying spleen and stopping diarrhea, supplementing the kidney to control the nocturnal, mental-tranquilization, it is insufficiency of the spleen long for treating Rush down, pass out semen, the disease such as involuntary emission, dysphoria insomnia.

Medicine of the present invention is the principle based on Chinese traditional treatment early carcinoma of stomach, from the pathomechanism and pharmacology according to early carcinoma of stomach Effect is thought：With regard to early carcinoma of stomach, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease Therapeutic effect.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned early carcinoma of stomach, prepared using the formula Medicine effect is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific of the present invention Embodiment is described in further detail：

Embodiment 1：

A kind of pill medicine for treating early carcinoma of stomach, it is characterised in that each component and mass parts of the medicine are than following institute Show：

Radix Angelicae Sinensis 120g, Poria cocos 120g, dried orange peel 95g, rhizoma cyperi 118g, banksia rose 95g, subprostrate sophora 95g, monkshood 80g, prepared rhizome of rehmannia 260g, Malt 120g, Rhizoma Sparganii 95g, ginseng 70g, ground bettle 80g, grass-leaved sweetflag 70g, pangolin 80g, storax 8g, agalloch eaglewood 23g, lotus seeds Meat 120g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of pill medicine for treating early carcinoma of stomach, it is characterised in that each component and mass parts of the medicine are than following institute Show：

Radix Angelicae Sinensis 140g, Poria cocos 140g, dried orange peel 105g, rhizoma cyperi 130g, banksia rose 105g, subprostrate sophora 105g, monkshood 90g, prepared rhizome of rehmannia 320g, malt 140g, Rhizoma Sparganii 105g, ginseng 80g, ground bettle 90g, grass-leaved sweetflag 80g, pangolin 90g, storax 9g, agalloch eaglewood 26g, 70~140g of Semen Nelumbinis, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of pill medicine for treating early carcinoma of stomach, it is characterised in that each component and mass parts of the medicine are than following institute Show：

Radix Angelicae Sinensis 160g, Poria cocos 160g, dried orange peel 120g, rhizoma cyperi 150g, banksia rose 120g, subprostrate sophora 120g, monkshood 100g, prepared rhizome of rehmannia It is 360g, malt 160g, Rhizoma Sparganii 120g, ginseng 90g, ground bettle 100g, grass-leaved sweetflag 90g, pangolin 100g, storax 10g, heavy Fragrant 30g, Semen Nelumbinis 160g, auxiliary material：Appropriate starch.

Model case：

Through clinical conditions early carcinoma of stomach patient totally 1357, the age is 772 of more than 68 years old, and only 585 are 68 years old Below.Being fully recovered in 1357 patients and extending life cycle has 439, effective 674, invalid 244.Total effective rate reaches 82%。

Claims (3)

1. a kind of pill medicine for treating early carcinoma of stomach, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

50~160g of Radix Angelicae Sinensis, 100~160g of Poria cocos, 60~120g of dried orange peel, 60~150g of rhizoma cyperi, 30~120g of the banksia rose, subprostrate sophora 30~120g, 30~100g of monkshood, 100~360g of prepared rhizome of rehmannia, 100~160g of malt, 30~120g of Rhizoma Sparganii, 15~90g of ginseng, 30~100g of ground bettle, 50~90g of grass-leaved sweetflag, 30~100g of pangolin, 3~10g of storax, 10~30g of agalloch eaglewood, Semen Nelumbinis 60~160g, auxiliary material：Appropriate starch.

2. the pill medicine for the treatment of early carcinoma of stomach according to claim 1, it is characterised in that each component of the medicine And its mass parts are than as follows：

58~140g of Radix Angelicae Sinensis, 115~140g of Poria cocos, 70~105g of dried orange peel, 70~130g of rhizoma cyperi, 38~105g of the banksia rose, subprostrate sophora 38~105g, 38~90g of monkshood, 115~320g of prepared rhizome of rehmannia, 115~140g of malt, 38~105g of Rhizoma Sparganii, 20~80g of ginseng, 38~90g of ground bettle, 58~80g of grass-leaved sweetflag, 38~90g of pangolin, 5~9g of storax, 12~26g of agalloch eaglewood, Semen Nelumbinis 70~ 140g, auxiliary material：Appropriate starch.

3. the pill medicine of the treatment early carcinoma of stomach according to claim 1 to 2, it is characterised in that the medicine it is each Component and its mass parts are than as follows：

Radix Angelicae Sinensis 120g, Poria cocos 120g, dried orange peel 95g, rhizoma cyperi 118g, banksia rose 95g, subprostrate sophora 95g, monkshood 80g, prepared rhizome of rehmannia 260g, Malt 120g, Rhizoma Sparganii 95g, ginseng 70g, ground bettle 80g, grass-leaved sweetflag 70g, pangolin 80g, storax 8g, agalloch eaglewood 23g, lotus seeds Meat 120g, auxiliary material：Appropriate starch.