CN105412785A - Traditional Chinese medicinal preparation for treating chronic gastritis - Google Patents
Traditional Chinese medicinal preparation for treating chronic gastritis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicinal preparation and a preparation method thereof, in particular to a traditional Chinese medicinal preparation for treating chronic gastritis and a preparation method of the traditional Chinese medicinal preparation. The traditional Chinese medicinal preparation is characterized by being prepared from the following traditional Chinese medicinal raw materials in parts by weight: 5-10 parts of fructus evodiae, 5-10 parts of perilla frutescens, 10-15 parts of fiveleaf akebia fruit, 10-15 parts of mandarin orange leaf, 5-10 parts of szechwan Chinaberry fruit, 5-10 parts of corydalis tuber, 10-15 parts of fructus amomi, 2-3 parts of a compound of glauber-salt and liquorice, 10-15 parts of radix coptis, 10-15 parts of radix adenophorae, 10-15 parts of radix ophiopogonis, 5-10 parts of radix paeoniae alba and 5-10 parts of raw liquorice root. The traditional Chinese medicinal preparation disclosed by the invention has the advantages that the adopted traditional Chinese medicines conform to the specifications of China Pharmacopeia, and the medicines are safe and reliable. The traditional Chinese medicinal preparation, which combines the various medicines, has functions of soothing liver and regulating qi, harmonizing stomach and relieving depression, nourishing yin and tonifying stomach; and the traditional Chinese medicinal preparation, on treating liver-stomach disharmony chronic gastritis with syndrome of insufficiency of stomach yin, has the characteristics of being concrete in curative effect, rapid to take effect, high in cure rate, free from side effects and the like.
Description
Technical field
The invention belongs to field of traditional Chinese, a kind of Chinese medicine preparation for the treatment of chronic gastritis.
Background technology
Chronic gastritis means the various chronic gastric Mucosal inflammatory pathological changes that different pathogeny causes, and be a kind of commonly encountered diseases, its sickness rate ranks first in various gastropathy.Since fiberendoscope extensive use, primary disease understanding is significantly improved.Common chronic superficial gastritis, chronic erosive gastritis and chronic atrophic gastritis.The intestinal epithelial metaplasia of the latter's mucosa, often involves cardia, reduces, also can involve body of stomach, with the forfeiture of secreting acid gland, cause gastric acid, the minimizing of pepsin and endogenous factors with G cell loss and gastrin secretion.
Chronic gastritis lacks specific symptom, and the weight of symptom and the lesion degree of gastric mucosa are also non-uniform.Most patient often asymptomatic or have degree different indigestion symptom as upper abdomen dull pain, loss of appetite, post-prandial fullness, acid regurgitation etc.Chronic Atrophic Gastritis Patients can have anemia, becomes thin, glossitis, diarrhoea etc., and person's upper abdominal pain that individuals patients accompanies mucosal erosion is comparatively obvious, and can have hemorrhage, as hematemesis, melena.Symptom is recurrent exerbation usually, and irregularities is suffered from abdominal pain, and pain often to come across in feeding process or after the meal, and majority is positioned at epigastrium, umbilicus week, some patients position are not fixed, and the intermittent dull pain of the lighter or dull pain, severe patient are violent angor.
Western medicine and medical practitioners prevent and treat chronic gastritis means, mainly concentrate on antacid, repair gastric mucosa, regulate digestive tract power, to kill in helicobacter pylori in a certain respect, thus can not give the therapeutic effect that Patients with Chronic Gastritis is satisfied; Meanwhile, its potential drug resistance problems also strongly limit its development.Comparatively speaking, Chinese medicine is according to the spirit of principle-method-recipe-medicines, determine the concrete pattern of syndrome of gastropathy, bestow respective party medicine, from improving patient's gastroenteric pathology situation and recovering gastrointestinal function two aspect undertaking therapy chronic gastritis, obtain certain effect in the treatment, especially to pathological change as inflammation, Mucosal atrophy, intestinal epithelial metaplasia or dysplasia etc., Chinese medicine advantageously.
The traditional Chinese medical science is divided into for chronic gastritis diagnostic criteria: liver-stomach disharmony type, weakness of the spleen and stomach (comprising deficiency and coldness) type, spleen and stomach damp-heat type, type of deficiency of stomach yin stomach function regulating network blood stasis type, wherein, for liver-stomach disharmony type chronic gastritis over the course for the treatment of, main employing liver-smoothing, qi-regulating, the method of stomach function regulating resolving depression, but applicant finds in a large amount of clinical course, because the modern life is accelerated and diet improvement, the patient of liver-stomach disharmony type chronic gastritis is often attended by deficiency of stomach-Yin symptom, or because of surfeit wine pungent, or consumption of YIN caused by febrile disease, consumption impairment of YIN liquid, raw in blood stasis, stomach mistake is moistened foster, with fall inappropriate caused by.Therefore, treatment liver-stomach disharmony type chronic gastritis is had higher requirement.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind of Chinese medicine preparation for the treatment of chronic gastritis, be particularly useful for treating the liver-stomach disharmony type chronic gastritis with deficiency of stomach-Yin symptom, it is evident in efficacy, safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
A kind of Chinese medicine preparation for the treatment of chronic gastritis of the present invention, according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 5 ~ 10 parts, common perilla 5 ~ 10 parts, Fructus Akebiae 10 ~ 15 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 10 ~ 15 parts, Fructus Toosendan 5 ~ 10 parts, corydalis tuber 5 ~ 10 parts, Fructus Amomi 10 ~ 15 parts, Matrii Sulfas Exsiccatus 2 ~ 3 parts, Rhizoma Coptidis 10 ~ 15 parts, Radix Adenophorae (Radix Glehniae) 10 ~ 15 parts, Radix Ophiopogonis 10 ~ 15 parts, the Radix Paeoniae Alba 5 ~ 10 parts, Radix Glycyrrhizae 5 ~ 10 parts.
Wherein, preferred version is as follows:
Can be according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 5 parts, common perilla 5 parts, Fructus Akebiae 10 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 10 parts, Fructus Toosendan 5 parts, corydalis tuber 5 parts, Fructus Amomi 10 parts, Matrii Sulfas Exsiccatus 2 parts, Rhizoma Coptidis 10 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, the Radix Paeoniae Alba 5 parts, Radix Glycyrrhizae 5 parts.
Also can be according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 10 parts, common perilla 10 parts, Fructus Akebiae 15 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 15 parts, Fructus Toosendan 10 parts, corydalis tuber 10 parts, Fructus Amomi 15 parts, Matrii Sulfas Exsiccatus 3 parts, Rhizoma Coptidis 15 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 15 parts, the Radix Paeoniae Alba 10 parts, Radix Glycyrrhizae 10 parts.
A kind of preparation method for the treatment of the Chinese medicine preparation of chronic gastritis of the present invention, prepare in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder immersion 10 ~ 20 minutes, add water again and do not have powder 3 ~ 5 centimetres, decoct with high heat and use slow fire boiling again instead 20 ~ 30 minutes to boiling, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
When taking, each 300ml, twice on the one.
Pharmacology analysis:
Fructus Evodiae: acrid in the mouth, temperature.Enter liver, spleen, stomach, large intestine, kidney channel.Warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, and stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
Common perilla: pungent, temperature.Expelling cold and relieving exterior syndrome, regulating the flow of QI to ease the stomach.For anemofrigid cold, headache, cough, distension and fullness of the chest and abdomen.
Fructus Akebiae: warm in nature flat, bitter and puckery flavor is pungent, nontoxic.Liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, also Hakuri, lumbago, hypochondriac pain, hernia, cave warp, and uterus drops.
Citrus chachiensis Hort. (C. Suavissima Tanaka): pungent, bitter, flat.Return spleen, stomach, Liver Channel.Circulation of qi promoting the chest stuffiness relieving, dispersing the stagnated liver-QI for regulating the stomach, removing toxicity for eliminating carbuncles.Main septum pectorale full vexed, distending pain over the hypochondrium, blockage of menstruation, diaphragm carbuncle, acute mastitis, breast carcinoma.
Fructus Toosendan: bitter, cold; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.Soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Corydalis tuber: warm in nature, acrid in the mouth is bitter, enters the heart, spleen, liver, lung.Have invigorate blood circulation, circulation of qi promoting, pain relieving effect.Its analgesic effect is remarkable, and site of action is extensive, and lasting and avirulence, be analgesic more excellent simply.
Fructus Amomi: pungent, temperature.Return spleen, stomach, kidney channel.Removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.
Matrii Sulfas Exsiccatus: salty, bitter, cold.Return stomach, large intestine channel.Purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant stomachache; External treatment laryngopharynx swelling and pain, aphtha of the mouth and tongue, gingival swelling and pain, conjunctival congestion, carbuncle, erysipelas.
Rhizoma Coptidis: bitter, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.
Radix Adenophorae (Radix Glehniae): sweet is cool.Clearing away heat and nourishing YIN, nourishing the lung to arrest cough.Cure mainly tracheitis, pertussis, cough due to lung-heat, cough up phlegm yellow thick.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
The Radix Paeoniae Alba: bitter, sour, is slightly cold.Return liver, spleen channel.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Radix Glycyrrhizae: sweet is flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
In medicament composing prescription of the present invention, Fructus Evodiae, common perilla, Fructus Akebiae, Citrus chachiensis Hort. (C. Suavissima Tanaka), Fructus Toosendan, corydalis tuber Six-element medicine dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of Qi and the middle Jiao, pain relieving, Fructus Amomi, Matrii Sulfas Exsiccatus, Rhizoma Coptidis three taste medicine stomach function regulating, heat clearing and damp drying, Radix Adenophorae (Radix Glehniae) and Radix Ophiopogonis close nourishing stomach-YIN, the Radix Paeoniae Alba and Radix Glycyrrhizae Gan Suanhuayin, moisten nourishing the stomach liquid, emergency and battalion, have the effect of relieving convulsion.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have the effect of depressed liver-energy dispersing and QI regulating, stomach function regulating resolving depression, yin nourishing stomach reinforcing, the liver-stomach disharmony type chronic gastritis having a deficiency of stomach-Yin symptom to treatment has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Outcome measure:
Choose Patients with Chronic Gastritis 60 example, and all confirmation is liver-stomach disharmony type chronic gastritis, man 35 example, female 25 example; 18 ~ 70 years old age, average 46.5 years old; The course of disease 10 weeks ~ 2 years, average 1.65.Take medicine of the present invention, each 300ml, one day twice.
Curative effect determinate standard: with reference to " chronic gastritis combination of Chinese and Western medicine diagnosis, dialectical and criterion of therapeutical effect " (tentative program), clinical recovery: clinical cardinal symptom all disappears, gastroscope check Active inflammation disappears, and chronic inflammatory disease is pass on well slightly.Effective: clinical cardinal symptom disappears, and secondary disease disappears substantially, gastroscope check Active inflammation disappears substantially, and chronic inflammatory disease takes a turn for the better.Effective: cardinal symptom obviously alleviates.Gastroscope check non-cancer lesion range shorter more than 1/2, inflammation alleviates to some extent.Invalid: symptom is without change, and gastroscopy does not reach effective standard, without deterioration person yet.
Result: effective 42 examples, effective 15 examples, invalid 3 examples, total effective rate 95%.
Below enumerate several model case
1, Song, man, 46 years old, people from Qingdao, case history 3 years, the scorching hot dull pain in symptom gastral cavilty portion 3 years, bitter taste, dry pharynx, constipation with dry stool was difficult to resolve, 3 ~ 5 days 1 row, and body of the tongue is light red, white and thin fur, and hospital outpatient is interrupted medical.Treat through medicine of the present invention, treat symptom after 14 days and obviously alleviate, adhere to taking after 2 months and fully recover, follow up a case by regular visits to and have no recurrence half a year.
2, Zhang, female, 36 years old, people from Qingdao, case history 1 year, symptom gastral cavilty feeling of fullness distending pain, belch, body of the tongue is light red, white and thin fur.Local hospital outpatient service is interrupted medical, and gastroscopy is shown: chronic superficial gastritis.Treat through medicine of the present invention, treat symptom after 7 days and obviously alleviate, adhere to taking after 1 month and fully recover, follow up a case by regular visits to and have no recurrence in 1 year.
Detailed description of the invention
The present invention will be further described by the following examples.
Embodiment 1:
A kind of Chinese medicine preparation for the treatment of chronic gastritis, according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 5 parts, common perilla 5 parts, Fructus Akebiae 10 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 10 parts, Fructus Toosendan 5 parts, corydalis tuber 5 parts, Fructus Amomi 10 parts, Matrii Sulfas Exsiccatus 2 parts, Rhizoma Coptidis 10 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, the Radix Paeoniae Alba 5 parts, Radix Glycyrrhizae 5 parts.
Embodiment 2:
A kind of Chinese medicine preparation for the treatment of chronic gastritis, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 10 parts, common perilla 10 parts, Fructus Akebiae 15 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 15 parts, Fructus Toosendan 10 parts, corydalis tuber 10 parts, Fructus Amomi 15 parts, Matrii Sulfas Exsiccatus 3 parts, Rhizoma Coptidis 15 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 15 parts, the Radix Paeoniae Alba 10 parts, Radix Glycyrrhizae 10 parts.
Embodiment 3:
According to the formula of embodiment 1 and embodiment 2, the Chinese medicine preparation of preparation treatment chronic gastritis in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, add water and cover powder and soak 20 minutes, add water again and do not have powder 3 centimetres, decoct with high heat and use slow fire boiling again instead 20 minutes to boiling, get filtrate; And then add water and do not have powder 3 centimetres, decoct with high heat and uses slow fire boiling again instead 15 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Claims (3)
1. treat the Chinese medicine preparation of chronic gastritis for one kind, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 5 ~ 10 parts, common perilla 5 ~ 10 parts, Fructus Akebiae 10 ~ 15 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 10 ~ 15 parts, Fructus Toosendan 5 ~ 10 parts, corydalis tuber 5 ~ 10 parts, Fructus Amomi 10 ~ 15 parts, Matrii Sulfas Exsiccatus 2 ~ 3 parts, Rhizoma Coptidis 10 ~ 15 parts, Radix Adenophorae (Radix Glehniae) 10 ~ 15 parts, Radix Ophiopogonis 10 ~ 15 parts, the Radix Paeoniae Alba 5 ~ 10 parts, Radix Glycyrrhizae 5 ~ 10 parts.
2. a kind of Chinese medicine preparation for the treatment of chronic gastritis according to claim 1, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 5 parts, common perilla 5 parts, Fructus Akebiae 10 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 10 parts, Fructus Toosendan 5 parts, corydalis tuber 5 parts, Fructus Amomi 10 parts, Matrii Sulfas Exsiccatus 2 parts, Rhizoma Coptidis 10 parts, Radix Adenophorae (Radix Glehniae) 10 parts, Radix Ophiopogonis 10 parts, the Radix Paeoniae Alba 5 parts, Radix Glycyrrhizae 5 parts.
3. a kind of Chinese medicine preparation for the treatment of chronic gastritis according to claim 1, it is characterized in that according to weight parts, be prepared from by following raw material of Chinese medicine: Fructus Evodiae 10 parts, common perilla 10 parts, Fructus Akebiae 15 parts, Citrus chachiensis Hort. (C. Suavissima Tanaka) 15 parts, Fructus Toosendan 10 parts, corydalis tuber 10 parts, Fructus Amomi 15 parts, Matrii Sulfas Exsiccatus 3 parts, Rhizoma Coptidis 15 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Radix Ophiopogonis 15 parts, the Radix Paeoniae Alba 10 parts, Radix Glycyrrhizae 10 parts.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106890296A (en) * | 2017-04-19 | 2017-06-27 | 青岛市第三人民医院 | Treat the Chinese medicine preparation of liver stomach damp-heat type chronic gastritis |
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| CN101347592A (en) * | 2008-04-18 | 2009-01-21 | 兰州理工大学 | Medicament compound for treating chronic gastritis and preparation method thereof |
| CN101632824A (en) * | 2008-07-24 | 2010-01-27 | 夏范音 | Chinese medicinal composition for treating gastritis |
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| CN101347592A (en) * | 2008-04-18 | 2009-01-21 | 兰州理工大学 | Medicament compound for treating chronic gastritis and preparation method thereof |
| CN101632824A (en) * | 2008-07-24 | 2010-01-27 | 夏范音 | Chinese medicinal composition for treating gastritis |
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| CN106890296A (en) * | 2017-04-19 | 2017-06-27 | 青岛市第三人民医院 | Treat the Chinese medicine preparation of liver stomach damp-heat type chronic gastritis |
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