CN105535436A - Oral traditional Chinese medicine pills for treating oesophagitis and preparation method thereof - Google Patents

Oral traditional Chinese medicine pills for treating oesophagitis and preparation method thereof Download PDF

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Publication number
CN105535436A
CN105535436A CN201610000878.4A CN201610000878A CN105535436A CN 105535436 A CN105535436 A CN 105535436A CN 201610000878 A CN201610000878 A CN 201610000878A CN 105535436 A CN105535436 A CN 105535436A
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chinese medicine
radix
traditional chinese
esophagitis
treatment
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任云翠
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Chengdu Fuhaosi Biotechnology Co Ltd
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Chengdu Fuhaosi Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835Aquilaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and aims at providing oral traditional Chinese medicine pills for treating oesophagitis based on the understanding mechanism of the traditional Chinese medicine science on oesophagitis. The traditional Chinese medicine pills are prepared from, by mass, 10 g to 23 g of adenophora tetraphylla, 6 g to 9 g of trogopterus dung, 6 g to 15 g of lilies, 10 g to 23 g of radix ophiopogonis, 2 g to 5 g of agilawood, 2.5 g to 12 g of liquorice roots, 5 g to 10 g of platycodon grandiflorum, 15 g to 25 g of honeysuckle, 15 g to 25 g of fructus forsythia, 7.5 g to 15 g of the seed of boat-fruited sterculia and a proper amount of honey. The medicine is good in medicine effect and rapid is effect taking and is a traditional Chinese medicine formulation capable of treating both symptoms and root causes.

Description

A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of Chinese medicine for oral administration ball for the treatment of esophagitis, particularly for the field of the Chinese medicine for oral administration ball and preparation method thereof of esophagitis patient.
Background technology
Esophagitis and esophagitis, general reference Esophageal Mucosa shallow-layer or deep tissues owing to being upset or damaging, Esophageal Mucosa generation edema and congested and inflammation that is that cause.Chemical irritation comprises gastric acid, bile, spirits and strong acid, highly basic, medicine etc.; Physical property stimulation comprises boiling hot food, beverage, foreign body in esophagus (fish spicule etc.) incarceration, long-term placement nasogastric tube etc.Because chemotherapy, radiotherapy cause esophagus Local Damaged, or the resistance decline of patient own causes tubercule bacillus, fungus (candidiasis) or viral infection also can cause esophagitis.The clinical modal reflux esophagitis being regurgitation of gastric juice and causing.
So, with regard to how finding a kind of medicine effectively can treating above-mentioned esophagitis, be the problem that we will solve at present.
Summary of the invention
Along with the development of China's Chinese medicine, on treatment esophagitis, people appreciate the advantage of the above-mentioned disease of Chinese traditional treatment gradually, and the advantage such as without any side effects and low cost over the course for the treatment of, for the present situation of the above-mentioned esophagitis of existing western medical treatment, the object of the invention is to be to provide a kind of Chinese medicine for oral administration ball for the treatment of esophagitis, to solve esophagitis patient restorative problem early.This medicine be with common Chinese medicine for raw material, there is instant effect, the feature such as evident in efficacy, and effectively can treat above-mentioned esophagitis one disease.
For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, it is characterized in that, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 10 ~ 23g, Oletum Trogopterori 6 ~ 9g, Bulbus Lilii 6 ~ 15g, Radix Ophiopogonis 10 ~ 23g,
Lignum Aquilariae Resinatum 2 ~ 5g, Radix Glycyrrhizae 2.5 ~ 12g, Radix Platycodonis 5 ~ 10g, Flos Lonicerae 15 ~ 25g, Fructus Forsythiae 15 ~ 25g, Semen Sterculiae Lychnophorae 7.5 ~ 15g, Mel are appropriate.
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, is characterized in that, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 12 ~ 20g, Oletum Trogopterori 6 ~ 8g, Bulbus Lilii 6 ~ 13g, Radix Ophiopogonis 12 ~ 20g,
Lignum Aquilariae Resinatum 3 ~ 4.5g, Radix Glycyrrhizae 3 ~ 11g, Radix Platycodonis 6 ~ 9g, Flos Lonicerae 16 ~ 22g, Fructus Forsythiae 16 ~ 22g, Semen Sterculiae Lychnophorae 8 ~ 13g, Mel are appropriate.
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, is characterized in that, each component of the Chinese medicine pill of described " preferred plan " and mass parts thereof are than as follows:
Radix Adenophorae 18g, Oletum Trogopterori 7g, Bulbus Lilii 12g, Radix Ophiopogonis 18g, Lignum Aquilariae Resinatum 4g, Radix Glycyrrhizae 10g, Radix Platycodonis 8g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Semen Sterculiae Lychnophorae 11g, Mel is appropriate.
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, is characterized in that, described method comprises the steps to be prepared from:
A, except Mel, after above-mentioned raw materials Chinese medicine is picked decontamination and dust, be ground into Powdered stand-by according to mass parts ratio;
B, traditionally prepare the method for Chinese medicine water-honeyed pill, after being sieved by ground powdery medicine, the medicine dedicated device putting into sterilizing room is mixed all, and (granularity of its water-honeyed pill is: 4.8mm-5.0mm) to be then prepared into water-honeyed pill, then dry, bottled sealing is for subsequent use.
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, is characterized in that, described instructions of taking is: taken for 3-5 time with every day by the water-honeyed pill prepared, dosage 3.5g/ time, and between two meal or on an empty stomach, delay pharynx containing changing, take medicine 7-28 days, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, Chinese dictionary and Chinese book on Chinese herbal medicine.The present invention selects wherein modal Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Radix Adenophorae, nature and flavor: sweet in the mouth, micro-hardship, cold nature, have effect of removing heat from the lung and dissipating phlegm, nourishing YIN to relieve dryness, reinforcing stomach reg fluid, are used for the treatment of fever due to yin deficiency, dryness of the lung dry cough, consumptive lung disease consumptive disease are coughed, sputum mixed with blood, sore throat pharyngalgia, Tianjin wound are thirsty;
Oletum Trogopterori, nature and flavor: sweet, warm, have effect of dissipating blood stasis, promoting the circulation of blood, pain relieving, are used for the treatment of the diseases such as menoxenia, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, gastric abscess, enterocele pain;
Bulbus Lilii, nature and flavor: sweet, micro-hardship, to be slightly cold, have effect of nourishing the lung to arrest cough, clearing away heart-fire for tranquillization, and after being used for the treatment of lung expense chronic cough, cough and spit expectorant blood, calentura, waste heat comes clear, fidgets due to deficiency palpitation with fear, staring spells, beriberi edema;
Radix Ophiopogonis, nature and flavor: sweet, micro-hardship, to be slightly cold, have YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire, are used for the treatment of dryness of the lung dry cough, the disease such as chronic consumptive disease cough, thirsty, the vexed insomnia of Tianjin wound, interior-heat are quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria;
Lignum Aquilariae Resinatum, nature and flavor: warm in nature, acrid in the mouth, hardship, have effect of promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma, are used for the treatment of the diseases such as the vexed pain of breast abdominal distention, gastrofrigid vomiting singultus, QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration;
Radix Glycyrrhizae, nature and flavor: sweet, flat, there is effect of QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription, be used for the treatment of asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, the anxious pain of extremity contraction, hysteria, cough and asthma, laryngopharynx swelling and pain, carbuncle skin ulcer swell and ache, infantile carbuncle and the disease such as medicine, alimentary toxicosis;
Radix Platycodonis, nature and flavor: bitter in the mouth, pungent, property are put down, there is lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus effect, be used for the treatment of cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, the full hypochondriac pain of born of the same parents, dysentery stomachache, uroschesis, uncomfortable in chest not freely, the disease such as hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus;
Flos Lonicerae, nature and flavor: sweet, cold, have effect of heat-clearing and toxic substances removing, are used for the treatment of epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furuncle, sore throat and multi-infection disease;
Fructus Forsythiae, nature and flavor: bitter, cold nature, has effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, anemopyretic cold, be used for the treatment of the diseases such as anemopyretic cold, epidemic febrile disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat;
Semen Sterculiae Lychnophorae, nature and flavor: sweet in the mouth, light, cool in nature, have effect of clearing heat and moistening lung, sore-throat relieving, bowel relieving relieving constipation, are used for the treatment of the diseases such as dry cough without phlegm, laryngopharynx swelling and pain, hoarseness, toothache, constipation with heat retention.
Medicine of the present invention is differential diagnosis of diseases based on Chinese traditional treatment esophagitis and the dialectical principle combined, think from pharmacological action and mechanism of action: with regard to esophagitis one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Detailed description of the invention
The present invention is exactly treatment for above-mentioned esophagitis and a kind of Chinese medicine formula proposed, and the medicine effect adopting this formula to prepare is good, instant effect, is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Be described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 18g, Oletum Trogopterori 7g, Bulbus Lilii 12g, Radix Ophiopogonis 18g, Lignum Aquilariae Resinatum 4g, Radix Glycyrrhizae 10g, Radix Platycodonis 8g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Semen Sterculiae Lychnophorae 11g, Mel is appropriate.
Embodiment 2:
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 20g, Oletum Trogopterori 8g, Bulbus Lilii 13g, Radix Ophiopogonis 20g, Lignum Aquilariae Resinatum 4.5g, Radix Glycyrrhizae 11g, Radix Platycodonis 9g, Flos Lonicerae 22g, Fructus Forsythiae 22g, Semen Sterculiae Lychnophorae 13g, Mel is appropriate.
Embodiment 3:
A kind of Chinese medicine for oral administration ball for the treatment of esophagitis and preparation method thereof, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 23g, Oletum Trogopterori 9g, Bulbus Lilii 15g, Radix Ophiopogonis 23g, Lignum Aquilariae Resinatum 5g, Radix Glycyrrhizae 12g, Radix Platycodonis 10g, Flos Lonicerae 25g, Fructus Forsythiae 25g, Semen Sterculiae Lychnophorae 15g, Mel is appropriate.
Model case:
Through clinical conditions esophagitis patient totally 160 examples, male 85 example, women 75 example, the age is more than 12 years old 90 routine, only has 70 examples to be less than 12 years old.156 examples of fully recovering in 160 routine patients, effective 4 examples, total effective rate reaches 100%.After treatment, sick announcement is fully recovered.

Claims (3)

1. treat the Chinese medicine for oral administration ball of esophagitis for one kind, it is characterized in that, each component of described Chinese medicine pill and mass parts thereof are than as follows: Radix Adenophorae 10 ~ 23g, Oletum Trogopterori 6 ~ 9g, Bulbus Lilii 6 ~ 15g, Radix Ophiopogonis 10 ~ 23g, Lignum Aquilariae Resinatum 2 ~ 5g, Radix Glycyrrhizae 2.5 ~ 12g, Radix Platycodonis 5 ~ 10g, Flos Lonicerae 15 ~ 25g, Fructus Forsythiae 15 ~ 25g, Semen Sterculiae Lychnophorae 7.5 ~ 15g, Mel is appropriate.
2. the Chinese medicine for oral administration ball for the treatment of esophagitis according to claim 1, is characterized in that, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 12 ~ 20g, Oletum Trogopterori 6 ~ 8g, Bulbus Lilii 6 ~ 13g, Radix Ophiopogonis 12 ~ 20g,
Lignum Aquilariae Resinatum 3 ~ 4.5g, Radix Glycyrrhizae 3 ~ 11g, Radix Platycodonis 6 ~ 9g, Flos Lonicerae 16 ~ 22g, Fructus Forsythiae 16 ~ 22g, Semen Sterculiae Lychnophorae 8 ~ 13g, Mel are appropriate.
3. according to the Chinese medicine for oral administration ball of the treatment esophagitis described in claim 1 to 2, it is characterized in that, each component of described Chinese medicine pill and mass parts thereof are than as follows:
Radix Adenophorae 18g, Oletum Trogopterori 7g, Bulbus Lilii 12g, Radix Ophiopogonis 18g, Lignum Aquilariae Resinatum 4g, Radix Glycyrrhizae 10g, Radix Platycodonis 8g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Semen Sterculiae Lychnophorae 11g, Mel is appropriate.
CN201610000878.4A 2016-01-04 2016-01-04 Oral traditional Chinese medicine pills for treating oesophagitis and preparation method thereof Withdrawn CN105535436A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106237115A (en) * 2016-09-20 2016-12-21 四川兴聚焦医药科技有限责任公司 A kind of Chinese medicine composition treating chronic pharyngitis and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147401A (en) * 2014-07-11 2014-11-19 广东广海大实业有限公司 Traditional Chinese medicine for treating esophagitis and preparation method thereof
CN107375815A (en) * 2017-07-31 2017-11-24 新乡医学院第附属医院 A kind of Chinese medicine for treating tumor in digestive tract

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147401A (en) * 2014-07-11 2014-11-19 广东广海大实业有限公司 Traditional Chinese medicine for treating esophagitis and preparation method thereof
CN107375815A (en) * 2017-07-31 2017-11-24 新乡医学院第附属医院 A kind of Chinese medicine for treating tumor in digestive tract

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨福义: "食道炎丸治疗食道炎12例", 《福建中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106237115A (en) * 2016-09-20 2016-12-21 四川兴聚焦医药科技有限责任公司 A kind of Chinese medicine composition treating chronic pharyngitis and preparation method thereof

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