CN107753841A - A kind of decoction medicine and preparation method for treating stomach cancer - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of decoction medicine for treating stomach cancer according to the understanding mechanism of Chinese traditional treatment stomach cancer, each component and its mass parts ratio of the medicine are as follows：25~100g of oldenlandia diffusa, 3~10g of the bark of official magnolia, 50~100g of valvate actinidia root, 5~15g of rascal, 3~12g of orange peel, 5~10g of the dried immature fruit of citron orange, 9~15g of hawthorn, 10~35g of chinaroot greenbrier, 10~35g of cuttle bone, 3~7g of fructus amomi, 6~15g of Divine Comedy, 3~7g of hairyvein agrimony, 3~18g of cacumen biotae, 15~65g of smilax；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of decoction medicine and preparation method for treating stomach cancer

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine for treating stomach cancer, particularly suffer from for stomach cancer The decoction medicine and the field of preparation method that person uses.

Background technology

Motherland's medical science thinks：Stomach cancer, stomach cancer rank first in the various malignant tumours in China, and incidence gastric cancer has obvious region Gender gap, it is evident as in the northwest in China than southern area with coastal region in east China incidence gastric cancer rate high.The age was sent out well at 50 years old More than, the ratio between men and women's incidence of disease is 2：1.The prognosis of stomach cancer and the pathological staging of stomach cancer, position, organization type, biological behaviour And remedy measures are relevant.

Clinical manifestation：Early carcinoma of stomach majority patient's non-evident sympton, a few peoples have Nausea and vomiting or similar to cankers Digestive symptoms.Pain and weight loss are the most common clinical symptoms of advanced gastric carcinoma.Patient Chang You more clearly on Symptom of digestive tract, it is loss of appetite, weak as disease progression Upper abdominal pain aggravates such as glutted after epigastric discomfort, feed.According to The position of tumour is different, also there is its Special Manifestations.Orifice of the stomach stomach bottom cancer can have retrosternal pain and progressive dysphagia；Pylorus is attached Near stomach cancer has pyloric stenosis performance；There can be the hemorrhage of digestive tract symptom such as spitting blood, melena after tumor destruction blood vessel.Belly persistently aches Often prompting expanding tumor exceeds coat of the stomach to pain, lays one's hand on and swells as recessed before supraclavicular lymph nodes enlargement, ascites, jaundice, abdominal mass, rectum Block etc..Late gastric cancer patient often may occur in which anaemia, become thin, malnutritive even cachexia etc. performance.The diffusion and transfer of stomach cancer There is following approach：

A. direct invasion

Orifice of the stomach stomach bottom cancer is easily invaded and lower esophagus, gastric cancer can infiltrate to duodenum.The stomach cancer for breaking up poor infiltrative growth is dashed forward After broken serous coat, the adjacent organs such as nethike embrane, colon, liver, pancreas are easily diffused to.

B. hematogenous metastasis

Occur late, cancer cell enters portal vein or body circulation is sent out at other positions to body, forms transfer stove.Common transfer Organ have liver, lung, pancreas, bone etc., be more using hepatic metastases.

C. peritoneal implantation metastasis

After stomach organization is infiltrated to outside serous coat, tumour cell comes off and is planted on peritonaeum and internal organs serous coat, forms transfer knot Section.Recessed metastatic carcinoma, digital rectal examination are can be found that before rectum.Metastatic tumor of ovary can occur for female patients stomach cancer.

D. Lymph Node Metastasis

It is the main route of metastasis of stomach cancer, the Lymph Node Metastasis rate of advanced gastric carcinoma is up to 70% or so, and early carcinoma of stomach can also have lymph Transfer.The rate of lymph-node metastasis of stomach cancer and the invasive depth of cancer stove are proportionate.The lymphatic metastasis of stomach cancer it is typically sequential by Walk progressive, but great-jump-forward Lymph Node Metastasis, i.e. first stop can also occur without transfer and second station has transfer.Whole latter stage stomach cancer can be through chest Supraclavicular lymph nodes shifts conduit to the left, or is transferred to umbilical region through ligamentum teres hepatis.

So, a kind of Chinese medicine composition that can effectively treat stomach cancer how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment stomach cancer, people gradually appreciate Chinese traditional treatment stomach The advantages of cancer, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment stomach cancer Present situation, the purpose of the present invention are to be to provide a kind of decoction medicine for treating stomach cancer, are got well early with solving patients with gastric cancer The problem of with life cycle is extended.The medicine be using common Chinese medicine as raw material, can by selecting rational medicine and mass parts ratio Above-mentioned stomach cancer one is effectively treated to demonstrate,prove.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of decoction for treating stomach cancer is provided Medicine and preparation method, it is characterised in that each component and mass parts of the medicine are than as follows：

25~100g of oldenlandia diffusa, 3~10g of the bark of official magnolia, 50~100g of valvate actinidia root, 5~15g of rascal, 3~12g of orange peel, the dried immature fruit of citron orange 5 ~10g, 9~15g of hawthorn, 10~35g of chinaroot greenbrier, 10~35g of cuttle bone, 3~7g of fructus amomi, 6~15g of Divine Comedy, 3~7g of hairyvein agrimony, 3~18g of cacumen biotae, 15~65g of smilax.

A kind of decoction medicine and preparation method for treating stomach cancer, it is characterised in that each component and quality of the medicine Part is than as follows：

30~90g of oldenlandia diffusa, 4~9g of the bark of official magnolia, 58~90g of valvate actinidia root, 6~13g of rascal, 5~11g of orange peel, the dried immature fruit of citron orange 6~ 9g, 10~13g of hawthorn, 11~31g of chinaroot greenbrier, 11~31g of cuttle bone, 4~6g of fructus amomi, 7~13g of Divine Comedy, 4~6g of hairyvein agrimony, side 5~16g of CedarLeaves, 18~56g of smilax.

A kind of decoction medicine and preparation method for treating stomach cancer, it is characterised in that each component and quality of the medicine Part is than as follows：

Oldenlandia diffusa 80g, bark of official magnolia 8g, valvate actinidia root 80g, rascal 12g, orange peel 10g, dried immature fruit of citron orange 8g, hawthorn 12g, chinaroot greenbrier 28g, crow Crafty bone 28g, fructus amomi 5g, Divine Comedy 12g, hairyvein agrimony 5g, cacumen biotae 14g, smilax 48g.

A kind of decoction medicine and preparation method for treating stomach cancer, it is characterised in that methods described comprises the following steps to prepare Form：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 50min, then again by soaked medicine and soak medicine Clarified solution be put into the lump in marmite, injected medicine 65mm cold boiling water carry out first time high heat decoction, wait decoct arrive 15min When, turn slow fire and boil 35 min, leaching decoction；2. the tepor boiling water that medicine 60mm was re-injected in the dregs of a decoction carries out second of intense fire Decoct, when 10min is arrived in decoction, turn slow fire and boil 30 min, leaching decoction；It is condensed into 3. decoction twice is mixed in 50% Decoction 450ml（Milliliter）.

A kind of decoction medicine and preparation method for treating stomach cancer, it is characterised in that the instructions of taking is：By what is prepared Herb liquid was taken with one day, and one portion per day, once a dose in the morning, afternoon and evening, dosage 150ml（Milliliter）/ time, take while hot.30 days are one The individual course for the treatment of, after 3 courses for the treatment of of taking medicine, symptom gradually mitigates, and stool recovers normal.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Oldenlandia diffusa, nature and flavor：It is sweet, light, cool, there is the effect of clearing heat and detoxicating, inducing diuresis to remove edema, promoting blood circulation and stopping pain, for treating intestines Carbuncle（Appendicitis）, sore furuncle poison, jaundice with damp-heat pathogen, difficult urination, external application controls boil carbuncle swells, venomous snake bite；

The bark of official magnolia, nature and flavor：Nature and flavor：It is bitter, pungent, warm, there is warming the middle warmer and descending qi, eliminating dampness and eliminating phlegm, the effect of relievining asthma, it is swollen for treating gastral cavity abdomen The diseases such as vexed, stomachache, gastric disorder causing nausea vomiting, cough and asthma；

Valvate actinidia root, nature and flavor：It is bitter, puckery, cool, there is the effect of clearing heat and detoxicating, for treating carbuncle, furuncle, abscess, women leukorrhea, leprosy The diseases such as disease；

Rascal, nature and flavor：Toil, tepor, there is the effect of soothing the liver relieving stagnant Qi, dissipating bind dissolving phlegm, for treating chest side of body gastral cavity pain, hernia Gas, dyspepsia, breast swell, newborn core, chronic malaria addiction block；

Orange peel, nature and flavor：Acrid flavour, slight bitter, temperature, have in qi-regulating tune, the effect of eliminating dampness and eliminating phlegm, for treating the taste stagnation of the circulation of vital energy, gastral cavity abdomen The disease such as uncomfortable in chest, indigestion and loss of appetite, loose stool caused by turgor, vomiting or turbi damp obstructing in middle-JIAO；

The dried immature fruit of citron orange, nature and flavor：It is bitter, cold, have relieving stagnant Qi, dissipate ruffian, rush down the effect of phlegm, disperse accumulations, for treat fullness and oppression of chest and abdomen, the obstruction of qi in the chest, ruffian pain, The illnesss such as phlegm addiction, oedema, dyspepsia, constipation, gastroptosis, metroptosis, prolapse of the anus；

Hawthorn, nature and flavor：Sour, sweet, tepor, there is food digesting stomach fortifying, scattered stasis, change the effect of turbid lipid-loweringing, for treating carnivorous product The diseases such as stagnant, gastral cavilty turgor, diarrhea dysentery abdominal pain, blood stasis closed, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipemia；

Chinaroot greenbrier, nature and flavor：It is sweet, sour, it is mild-natured, have expelling wind and removing dampness, removing toxicity for eliminating carbuncles the effect of, for treat arthralgia pain due to rheumatism, stranguria with turbid discharge, Under band, diarrhea, dysentery, carbuncle sore tumefacting virus, stubborn dermatitis, burn and scald, removing toxic substances, wind dispelling, sore section key medicine, cancer, the disease such as quench one's thirst；

Cuttle bone, nature and flavor：Taste is salty, puckery, warm-natured, has the effect of astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving haperacidity analgesic, hygroscopic sore, uses In treatment spitting blood, uterine bleeding, have blood in stool, bleeding from five sense organs or subcutaneous tissue, traumatic bleeding, emission due to the kidney deficiency involuntary emission, leukorrhea with reddish discharge, have a stomachache noisy, belch The diseases such as pantothenic acid, eczema ulcer；

Fructus amomi, nature and flavor：It is acrid flavour, warm-natured, there is the effect of dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive, for treat it is wet it is turbid in The diseases such as resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, pernicious vomiting, fetal irritability；

Divine Comedy, nature and flavor：It is sweet, pungent, warm, have promoting digestion and removing indigestion, strengthening the spleen and stomach the effect of, for Therapeutic diet stagnation, indigestion, The disease such as abdominal fullness and distention, poor appetite, vomiting dysentery and married woman's postpartum congestion and abdominal pain, the big hard product of children's abdomen；

Hairyvein agrimony, nature and flavor：It is acrid flavour, warm-natured, there is the effect of dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive, for treat it is wet it is turbid in The diseases such as resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, pernicious vomiting, fetal irritability；

Cacumen biotae, nature and flavor：It is bitter, puckery, be slightly cold, have cool blood, hemostasis the effect of, for treat haematemesiss, bleeding from five sense organs or subcutaneous tissue, have blood in stool, collapse blood, urinate The diseases such as blood；

Smilax, nature and flavor：It is sweet, light, flat, there is the effect of removing toxic substances, dehumidify, be easing joint movement, for treating syphilis and mercury poisoning institute Under the limbs contraction of cause, arthralgia and myalgia, damp and hot stranguria with turbid discharge, band, the disease such as carbuncle swells, scrofula, mange.

Medicine of the present invention is the principle based on Chinese traditional treatment stomach cancer, is recognized from the pathomechanism according to stomach cancer and pharmacological action For：Stomach cancer one is demonstrate,proved, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good treatment to above-mentioned disease Effect.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned stomach cancer, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of decoction medicine for treating stomach cancer, it is characterised in that each component and mass parts of the medicine are than as follows：

Oldenlandia diffusa 80g, bark of official magnolia 8g, valvate actinidia root 80g, rascal 12g, orange peel 10g, dried immature fruit of citron orange 8g, hawthorn 12g, chinaroot greenbrier 28g, crow Crafty bone 28g, fructus amomi 5g, Divine Comedy 12g, hairyvein agrimony 5g, cacumen biotae 14g, smilax 48g.

Embodiment 2：

A kind of decoction medicine for treating stomach cancer, it is characterised in that each component and mass parts of the medicine are than as follows：

Oldenlandia diffusa 90g, bark of official magnolia 9g, valvate actinidia root 90g, rascal 13g, orange peel 11g, dried immature fruit of citron orange 9g, hawthorn 13g, chinaroot greenbrier 31g, crow Crafty bone 31g, fructus amomi 6g, Divine Comedy 13g, hairyvein agrimony 6g, cacumen biotae 16g, smilax 56g.

Embodiment 3：

A kind of decoction medicine for treating stomach cancer, it is characterised in that each component and mass parts of the medicine are than as follows：

Oldenlandia diffusa 100g, bark of official magnolia 10g, valvate actinidia root 100g, rascal 15g, orange peel 12g, dried immature fruit of citron orange 10g, hawthorn 15g, chinaroot greenbrier 35g, cuttle bone 35g, fructus amomi 7g, Divine Comedy 15g, hairyvein agrimony 7g, cacumen biotae 18g, smilax 65g.

Model case：

Through clinical conditions patients with gastric cancer totally 1218, the age is 659 of more than 59 years old, and only 559 are less than 59 years old. Being fully recovered in 1218 patients and extending life cycle has 395, effective 567, invalid 256.Total effective rate is up to 79%.

Claims (3)

1. a kind of decoction medicine for treating stomach cancer, it is characterised in that each component and its mass parts of the medicine are than following institute Show：

25~100g of oldenlandia diffusa, 3~10g of the bark of official magnolia, 50~100g of valvate actinidia root, 5~15g of rascal, 3~12g of orange peel, the dried immature fruit of citron orange 5 ~10g, 9~15g of hawthorn, 10~35g of chinaroot greenbrier, 10~35g of cuttle bone, 3~7g of fructus amomi, 6~15g of Divine Comedy, 3~7g of hairyvein agrimony, 3~18g of cacumen biotae, 15~65g of smilax.

2. it is according to claim 1 treatment stomach cancer decoction medicine, it is characterised in that each component of the medicine and its Mass parts are than as follows：

30~90g of oldenlandia diffusa, 4~9g of the bark of official magnolia, 58~90g of valvate actinidia root, 6~13g of rascal, 5~11g of orange peel, the dried immature fruit of citron orange 6~ 9g, 10~13g of hawthorn, 11~31g of chinaroot greenbrier, 11~31g of cuttle bone, 4~6g of fructus amomi, 7~13g of Divine Comedy, 4~6g of hairyvein agrimony, side 5~16g of CedarLeaves, 18~56g of smilax.

3. the decoction medicine of the treatment stomach cancer according to claim 1 to 2, it is characterised in that each component of the medicine And its mass parts are than as follows：

Oldenlandia diffusa 80g, bark of official magnolia 8g, valvate actinidia root 80g, rascal 12g, orange peel 10g, dried immature fruit of citron orange 8g, hawthorn 12g, chinaroot greenbrier 28g, crow Crafty bone 28g, fructus amomi 5g, Divine Comedy 12g, hairyvein agrimony 5g, cacumen biotae 14g, smilax 48g.