CN107802740A - A kind of capsule medicine for treating stomach cancer and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of capsule medicine for treating stomach cancer according to the understanding mechanism of Chinese traditional treatment stomach cancer, each component and its mass parts ratio of the medicine are as follows：30~90g of rhizoma arisaematis, 30~100g of butterflybush flower, 30~100g of pangolin, 150~360g of indian adenosma herb, 50~100g of dried pinellia, 30~130g of Common Cissampelos Herb, 30~70g of ergcibe obtusifolia, 30~80g of stachyurus pith, 30~120g of spina gleditsiae, 30~100g of Fructus Malvae Vertillatae, 20~70g of fennelflower seed, 100~160g of cynomorium songaricum, 30~70g of edible tulip, 20~40g of Herba Hyperici Monogyni, include 100~160g of beach wormwood；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine for treating stomach cancer and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for treating stomach cancer, particularly for stomach cancer The field of the capsule medicine that patient uses and preparation method thereof.

Background technology

Shown according to documents and materials：Stomach cancer, stomach cancer rank first in the various malignant tumours in China, and incidence gastric cancer has significantly Domain gender gap, it is evident as in the northwest in China than southern area with coastal region in east China incidence gastric cancer rate high.The age is sent out well 50 More than year, the ratio between men and women's incidence of disease is 2：1.The prognosis of stomach cancer and the pathological staging of stomach cancer, position, organization type, biological scholarship and moral conduct For and remedy measures it is relevant.

Clinical manifestation：Early carcinoma of stomach majority patient's non-evident sympton, a few peoples have Nausea and vomiting or similar to cankers Digestive symptoms.Pain and weight loss are the most common clinical symptoms of advanced gastric carcinoma.Patient Chang You more clearly on Symptom of digestive tract, it is loss of appetite, weak as disease progression Upper abdominal pain aggravates such as glutted after epigastric discomfort, feed.According to The position of tumour is different, also there is its Special Manifestations.Orifice of the stomach stomach bottom cancer can have retrosternal pain and progressive dysphagia；Pylorus is attached Near stomach cancer has pyloric stenosis performance；There can be the hemorrhage of digestive tract symptom such as spitting blood, melena after tumor destruction blood vessel.Belly persistently aches Often prompting expanding tumor exceeds coat of the stomach to pain, lays one's hand on and swells as recessed before supraclavicular lymph nodes enlargement, ascites, jaundice, abdominal mass, rectum Block etc..Late gastric cancer patient often may occur in which anaemia, become thin, malnutritive even cachexia etc. performance.The diffusion and transfer of stomach cancer There is following approach：

A. direct invasion

Orifice of the stomach stomach bottom cancer is easily invaded and lower esophagus, gastric cancer can infiltrate to duodenum.The stomach cancer for breaking up poor infiltrative growth is dashed forward After broken serous coat, the adjacent organs such as nethike embrane, colon, liver, pancreas are easily diffused to.

B. hematogenous metastasis

Occur late, cancer cell enters portal vein or body circulation is sent out at other positions to body, forms transfer stove.Common transfer Organ have liver, lung, pancreas, bone etc., be more using hepatic metastases.

C. peritoneal implantation metastasis

After stomach organization is infiltrated to outside serous coat, tumour cell comes off and is planted on peritonaeum and internal organs serous coat, forms transfer knot Section.Recessed metastatic carcinoma, digital rectal examination are can be found that before rectum.Metastatic tumor of ovary can occur for female patients stomach cancer.

D. Lymph Node Metastasis

It is the main route of metastasis of stomach cancer, the Lymph Node Metastasis rate of advanced gastric carcinoma is up to 70% or so, and early carcinoma of stomach can also have lymph Transfer.The rate of lymph-node metastasis of stomach cancer and the invasive depth of cancer stove are proportionate.The lymphatic metastasis of stomach cancer it is typically sequential by Walk progressive, but great-jump-forward Lymph Node Metastasis, i.e. first stop can also occur without transfer and second station has transfer.Whole latter stage stomach cancer can be through chest Supraclavicular lymph nodes shifts conduit to the left, or is transferred to umbilical region through ligamentum teres hepatis.

So, a kind of Chinese medicine composition that can effectively treat stomach cancer how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment stomach cancer, people gradually appreciate Chinese traditional treatment stomach The advantages of cancer, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment stomach cancer Present situation, the purpose of the present invention are to be to provide a kind of capsule medicine for treating stomach cancer, recover strong early to solve patients with gastric cancer The problem of health and extension life cycle.The medicine be using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, Above-mentioned stomach cancer can effectively be treated.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：A kind of capsule for treating stomach cancer is provided Agent medicine and preparation method thereof, it is characterised in that each component and mass parts of the medicine are than as follows：

30~90g of rhizoma arisaematis, 30~100g of butterflybush flower, 30~100g of pangolin, 150~360g of indian adenosma herb, dried pinellia 50~ 100g, 30~130g of Common Cissampelos Herb, 30~70g of ergcibe obtusifolia, 30~80g of stachyurus pith, 30~120g of spina gleditsiae, Fructus Malvae Vertillatae 30~ 100g, 20~70g of fennelflower seed, 100~160g of cynomorium songaricum, 30~70g of edible tulip, 20~40g of Herba Hyperici Monogyni, include beach wormwood 100~ 160g, auxiliary material：Appropriate starch.

A kind of capsule medicine for treating stomach cancer and preparation method thereof, it is characterised in that each component of the medicine and Mass parts are than as follows：

38~80g of rhizoma arisaematis, 38~90g of butterflybush flower, 38~90g of pangolin, 180~320g of indian adenosma herb, 58~90g of dried pinellia, 38~115g of Common Cissampelos Herb, 38~60g of ergcibe obtusifolia, 38~70g of stachyurus pith, 38~105g of spina gleditsiae, 38~90g of Fructus Malvae Vertillatae, black race 36~60g of grass seed, 115~140g of cynomorium songaricum, 38~60g of edible tulip, 26~36g of Herba Hyperici Monogyni, include 115~140g of beach wormwood, auxiliary material： Appropriate starch.

A kind of capsule medicine for treating stomach cancer and preparation method thereof, it is characterised in that each component of the medicine and Mass parts are than as follows：

Rhizoma arisaematis 70g, butterflybush flower 80g, pangolin 80g, indian adenosma herb 260g, dried pinellia 80g, Common Cissampelos Herb 100g, ergcibe obtusifolia 52g, Stachyurus pith 60g, spina gleditsiae 95g, Fructus Malvae Vertillatae 80g, fennelflower seed 52g, cynomorium songaricum 120g, edible tulip 52g, Herba Hyperici Monogyni 32g, include Beach wormwood 120g, auxiliary material：Appropriate starch.

A kind of capsule medicine for treating stomach cancer and preparation method thereof, it is characterised in that methods described comprises the following steps It is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, the raw material Chinese medicine wrapped is put into after soaking 55min in cold boiling water, then soaked medicine is put into marmite and decocted Three times：1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when 15min is arrived in decoction, turns slow fire and boils 115 Min, leaching decoction；2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, when 10min is arrived in decoction, is turned Slow fire boils 105 min, leaching decoction；3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct During to 8min, turn slow fire and boil 90 min, leaching decoction；4. merging decoction three times, and it is concentrated under reduced pressure into every milliliter contained 3g Standard after, that is, obtain drug extract.

C, by the extract dry prepared in above-mentioned B, sterilization, and it is standby according to mass parts ratio to be ground into superfine end；

D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh thing mistake ground in C After sieve, and auxiliary material is put into medicine device and is well mixed in the lump, is then prepared into capsule（Total length after its capsule is sealed is 23.3mm, medicinal powder capacity 0.4~0.5g/ grains）, then polish, sterilize, sealed packaging.

A kind of capsule medicine for treating stomach cancer and preparation method thereof, it is characterised in that the instructions of taking is：It will prepare Good capsule medicine is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 2g（4）/ time, warm water delivery service.30 days For a course for the treatment of, 5 courses for the treatment of of taking medicine, sign and symptom significantly improve, and focus significantly improves, defecated normally.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Rhizoma arisaematis, nature and flavor：It is bitter, pungent, warm, it is poisonous, there is the effect of eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating, it is stupid for treating The diseases such as productive cough is coughed, anemophlegmatic vertigo, heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, hemiplegia, epilepsy, infantile convulsion, lockjaw；

Butterflybush flower, nature and flavor：It is sweet, cold nature, cool in nature, there is the effect of heat-clearing nourishing the liver, removing nebula, swollen for treating hot eyes Bitterly, the disease such as more tear photophobia, screen of looking unfamiliar film, hepatasthenia dim eyesight, blurring of vision；

Pangolin, nature and flavor：It is salty, be slightly cold, have invigorate blood circulation, it is lower breast, detumescence and apocenosis the effect of, for treating Amenorrhea, Disorder lumps in the abdomen, breast The diseases such as juice is obstructed, arthralgia pain due to rheumatism, spasm of limbs, carbuncle swells, scrofula subcutaneous nodule；

Indian adenosma herb, nature and flavor：It is acrid flavour, slight bitter, mild-natured, there is expelling wind to resolve the exterior, dampness elimination to disappear the effect of stagnant, for treat cold headache, The diseases such as heating, stomachache diarrhea, indigestion；

Dried pinellia, nature and flavor：It is pungent, warm, it is poisonous, there is the effect of eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, for treating damp phlegm Cough, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus, gall subcutaneous nodule, swollen ulcer drug；

Common Cissampelos Herb, nature and flavor：It is sweet, bitter, warm-natured, there is the effect of swelling and pain relieving, hemostasis, myogenic, for treating wound swelling and pain, wound Hinder the diseases such as bleeding；

Ergcibe obtusifolia, nature and flavor：It is acrid flavour, warm-natured, it is slightly poisonous, there is the effect of dispelling wind and eliminating dampness, swelling and pain relieving, for treating rheumatism numbness Bitterly, the disease such as hemiplegia, treating swelling and pain by traumatic injury；

Stachyurus pith, nature and flavor：It is sweet, light, cold, have heat-clearing, diuresis, it is lower newborn the effect of, for treating difficult urination, stranguria, milk Not inferior disease；

Spina gleditsiae, nature and flavor：It is acrid flavour, warm-natured, there is the effect of detumescence eliminating toxic, apocenosis, desinsection, for treat ulcer from the beginning of or purulence into Do not burst, control mange leprosy outside；

Fructus Malvae Vertillatae, nature and flavor：It is sweet, puckery, cool in nature, have reducing fever and causing diuresis, detumescence the effect of, for treat renal shutdown, oedema, it is thirsty, The diseases such as urinary tract infections；

Fennelflower seed, nature and flavor：It is sweet, pungent, warm-natured, have kidney-tonifying and brain tonic, stimulate the menstrual flow, promoting lactation, diuresis the effect of, for treating tinnitus The diseases such as forgetful, Amenorrhea is newborn less, heat gonorrhea, urolithiasis；

Cynomorium songaricum, nature and flavor：It is sweet, warm, there is the effect of kidney-replenishing, benefiting essence-blood, relax bowel, for treating impotence involuntary emission, waist and knee acid The diseases such as soft, muscles and bones is powerless, constipation；

Edible tulip, nature and flavor：Sweet, micro-pungent, cold in nature, mild toxicity, there is the effect of clearing heat and detoxicating, dispersing swelling and dissipating binds, for treating ulcer The diseases such as malignant sore, scrofula tuberculosis, pharyngalgia larynx numbness, snake, insect bite；

Herba Hyperici Monogyni, nature and flavor：It is pungent, cold, there is the effect of soothing liver-qi stagnation, clearing heat and promoting diuresis, detumescence promoting lactation, for treating hepatic depression The diseases such as knot, feelings will is not smooth, ambition is gloomy, painful swelling of joints, acute mastitis, breast are few；

Include beach wormwood, nature and flavor：It is cold, sweet, bitter, have clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation the effect of, for treat cough with lung heat, The diseases such as the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, acute appendicitis swelling and pain, constipation.

Medicine of the present invention is the principle based on Chinese traditional treatment stomach cancer, is recognized from the pathomechanism according to stomach cancer and pharmacological action For：With regard to stomach cancer, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned stomach cancer, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of capsule medicine for treating stomach cancer, it is characterised in that each component and mass parts of the medicine are than as follows：

Rhizoma arisaematis 70g, butterflybush flower 80g, pangolin 80g, indian adenosma herb 260g, dried pinellia 80g, Common Cissampelos Herb 100g, ergcibe obtusifolia 52g, Stachyurus pith 60g, spina gleditsiae 95g, Fructus Malvae Vertillatae 80g, fennelflower seed 52g, cynomorium songaricum 120g, edible tulip 52g, Herba Hyperici Monogyni 32g, include Beach wormwood 120g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of capsule medicine for treating stomach cancer, it is characterised in that each component and mass parts of the medicine are than as follows：

Rhizoma arisaematis 80g, butterflybush flower 90g, pangolin 90g, indian adenosma herb 320g, dried pinellia 90g, Common Cissampelos Herb 115g, ergcibe obtusifolia 60g, Stachyurus pith 70g, spina gleditsiae 105g, Fructus Malvae Vertillatae 90g, fennelflower seed 60g, cynomorium songaricum 140g, edible tulip 60g, Herba Hyperici Monogyni 36g, Include beach wormwood 140g, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of capsule medicine for treating stomach cancer, it is characterised in that each component and mass parts of the medicine are than as follows：

Rhizoma arisaematis 90g, butterflybush flower 100g, pangolin 100g, indian adenosma herb 360g, dried pinellia 00g, Common Cissampelos Herb 130g, ergcibe obtusifolia 70g, stachyurus pith 80g, spina gleditsiae 120g, Fructus Malvae Vertillatae 100g, fennelflower seed 70g, cynomorium songaricum 160g, edible tulip 70g, Herba Hyperici Monogyni 40g, include beach wormwood 160g, auxiliary material：Appropriate starch.

Model case：

Through clinical conditions patients with gastric cancer totally 1230, the age is 730 of over-65s, and only 500 are less than 65 years old. Being fully recovered in 1230 patients and extending life cycle has 395, effective 577, invalid 258.Total effective rate is up to 79%.

Claims (3)

1. a kind of capsule medicine for treating stomach cancer, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

30~90g of rhizoma arisaematis, 30~100g of butterflybush flower, 30~100g of pangolin, 150~360g of indian adenosma herb, dried pinellia 50~ 100g, 30~130g of Common Cissampelos Herb, 30~70g of ergcibe obtusifolia, 30~80g of stachyurus pith, 30~120g of spina gleditsiae, Fructus Malvae Vertillatae 30~ 100g, 20~70g of fennelflower seed, 100~160g of cynomorium songaricum, 30~70g of edible tulip, 20~40g of Herba Hyperici Monogyni, include beach wormwood 100~ 160g, auxiliary material：Appropriate starch.

2. it is according to claim 1 treatment stomach cancer capsule medicine, it is characterised in that each component of the medicine and Its mass parts is than as follows：

38~80g of rhizoma arisaematis, 38~90g of butterflybush flower, 38~90g of pangolin, 180~320g of indian adenosma herb, 58~90g of dried pinellia, 38~115g of Common Cissampelos Herb, 38~60g of ergcibe obtusifolia, 38~70g of stachyurus pith, 38~105g of spina gleditsiae, 38~90g of Fructus Malvae Vertillatae, black race 36~60g of grass seed, 115~140g of cynomorium songaricum, 38~60g of edible tulip, 26~36g of Herba Hyperici Monogyni, include 115~140g of beach wormwood, auxiliary material： Appropriate starch.

3. the capsule medicine of the treatment stomach cancer according to claim 1 to 2, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

Rhizoma arisaematis 70g, butterflybush flower 80g, pangolin 80g, indian adenosma herb 260g, dried pinellia 80g, Common Cissampelos Herb 100g, ergcibe obtusifolia 52g, Stachyurus pith 60g, spina gleditsiae 95g, Fructus Malvae Vertillatae 80g, fennelflower seed 52g, cynomorium songaricum 120g, edible tulip 52g, Herba Hyperici Monogyni 32g, include Beach wormwood 120g, auxiliary material：Appropriate starch.