CN107929376A - A kind of Chinese medicine composition for treating gout and its preparation method and application - Google Patents
A kind of Chinese medicine composition for treating gout and its preparation method and application Download PDFInfo
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- CN107929376A CN107929376A CN201711323809.8A CN201711323809A CN107929376A CN 107929376 A CN107929376 A CN 107929376A CN 201711323809 A CN201711323809 A CN 201711323809A CN 107929376 A CN107929376 A CN 107929376A
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- 208000004371 toothache Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 210000001364 upper extremity Anatomy 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
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Abstract
The invention discloses a kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and oral preparation of Chinese traditional medicinal, the Chinese medicinal plaster includes the raw material of following parts by weight proportioning：2~5 parts of crotons skin, 1~3 part of monkshood, 2~5 parts of radix aconiti agrestis, 3~6 parts of safflower, 0.1~0.3 part of borneol, 3~6 parts of edible oil；The oral preparation of Chinese traditional medicinal includes the raw material of following parts by weight proportioning：3~5 parts of the radix paeoniae rubrathe, 2~4 parts of great burdock achene, 1~3 part of puncture vine, 3~5 parts windproof, 4~8 parts of duckweed, 2~4 parts of kuh-seng, 4~8 parts of schizonepeta, 3~5 parts of Angelica sinensis tail, 2~4 parts of dandelion, 3~5 parts of honeysuckle, 2~5 parts of Fructus Forsythiae, 3~5 parts of notopterygium root, 2~4 parts of cicada slough, 1~3 part of radix glycyrrhizae.The invention also discloses the preparation method and application of the Chinese medicine composition.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine composition for treating gout and preparation method thereof and
Using.
Background technology
Gout is the crystal correlation arthropathy caused by monosodium urate salt (MSU) deposits, and refers in particular to acute characteristic joint
Scorching and chronic gout stone disease, mainly includes acute attack arthritis, tophus formation, tophaceous chornic arthritis, urine
Hydrochlorate nephrosis and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.From the point of view of the traditional Chinese medical science, the cause of disease of gout
One of be to catch cold by wet, and the wet stagnant internal resistance of the turbid stasis of blood is then its main pathogenesis, and this wet turbid heresy, from it in outer, and life in
It is interior.Because patient is mostly the body of the plump phlegm wet of body, and it is addicted to drink, likes and eat good, causes visceral dysfunction, ascending the clear and descending the turbid
Have no right, make the stagnant resistance of phlegm wet among blood vessels, it is difficult to which letting out, mutually ties with blood and be the turbid stasis of blood, is stranded in passages through which vital energy circulates, then joint swells and ache, knot
Section deformity, very then diabrosis, seepage fat；Or closingization heat, gather into poison, undermine spleen kidney, just then pain in the back, hematuria, be then jammed long
Three is burnt, and be in " obstruction and rejection " danger time, i.e., " gouty ephritis " and cause the disease of renal failure.
The medicine that the prior art is used to treat or alleviate gout symptom mainly includes non-steroidal anti-inflammatory drugs, colchicin, sugar
Cortin etc., but non-steroidal anti-inflammatory drugs can cause intestines and stomach side reaction mostly, and significant discomfort, sugared cortical hormone are brought for pill taker
It is plain pill taker is produced dependence, " knock-on " phenomenon often occurs after drug withdrawal, is not suitable for long-time service.But patient with gout is not
Arthralgia caused by gout, the swelling even symptom such as function limitation can be then afforded using medicine, greatly affected patient
Quality of life.
The content of the invention
For gout common drug there are intestines and stomach side reaction, be also easy to produce the problem of dependence, the present invention provides one kind and controls
Treat the Chinese medicine composition of gout.
And the present invention also provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment gout.
And the present invention also provides above-mentioned treatment gout Chinese medicine composition as treatment gout medicine application.
To achieve the above object of the invention, the embodiment of the present invention employs following technical solution：
A kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and oral preparation of Chinese traditional medicinal, the Chinese medicinal plaster include
The raw material of following parts by weight proportioning：2~5 parts of crotons skin, 1~3 part of monkshood, 2~5 parts of radix aconiti agrestis, 3~6 parts of safflower, borneol 0.1
~0.3 part, 3~6 parts of edible oil；The oral preparation of Chinese traditional medicinal includes the raw material of following parts by weight proportioning：3~5 parts of the radix paeoniae rubrathe, ox
2~4 parts of burdock, 1~3 part of puncture vine, 3~5 parts windproof, 4~8 parts of duckweed, 2~4 parts of kuh-seng, 4~8 parts of schizonepeta, Angelica sinensis tail 3~5
Part, 2~4 parts of dandelion, 3~5 parts of honeysuckle, 2~5 parts of Fructus Forsythiae, 3~5 parts of notopterygium root, 2~4 parts of cicada slough, 1~3 part of radix glycyrrhizae.
Relative to the prior art, the Chinese medicine composition ratio that passes through preferred above component for the treatment of gout provided by the present invention
Chinese medicine preparation is made in example, and emplastrum is used in conjunction with oral formulations, makes to play synergistic effect between each component, windproof, righting, subtract
Poison, synergy, can preferably improve gout symptom and treatment gout.
Present invention also offers a kind of preparation method of the Chinese medicine composition of above-mentioned treatment gout, the Chinese medicinal plaster
By the raw material through crushing, mixing；Peroral dosage form is made by the raw material in the oral preparation of Chinese traditional medicinal after decoction.
The preparation method process is simple, by disintegrating process, adds the surface area of medicine, is more advantageous to active ingredient
Release, by decocting process, improves the bioavilability for decocting active ingredient in raw material, it is easier to and absorb and play effect,
By the way that oral formulations are made, the formulation that suitable patient takes is made in active ingredient, facilitates patient to use.
Chinese medicine composition the present invention also provides above-mentioned treatment gout is as the application for treating gout medicine.
External plaster and oral formulations use in conjunction for oral administration, jointly performance drug effect simultaneously are played mutually to be attenuated and increased by the present invention
The effect of effect, preferably plays and alleviates gout symptom, treatment pain wind action, so as to improve patients ' life quality.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
The embodiment of the present invention provides a kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and oral preparation of Chinese traditional medicinal,
The Chinese medicinal plaster includes the raw material of following parts by weight proportioning：It is 2~5 parts of crotons skin, 1~3 part of monkshood, 2~5 parts of radix aconiti agrestis, red
Spend 3~6 parts, 0.1~0.3 part of borneol, 3~6 parts of edible oil；The oral preparation of Chinese traditional medicinal includes the original of following parts by weight proportioning
Material：3~5 parts of the radix paeoniae rubrathe, 2~4 parts of great burdock achene, 1~3 part of puncture vine, 3~5 parts windproof, 4~8 parts of duckweed, 2~4 parts of kuh-seng, schizonepeta 4
~8 parts, 3~5 parts of Angelica sinensis tail, 2~4 parts of dandelion, 3~5 parts of honeysuckle, 2~5 parts of Fructus Forsythiae, 3~5 parts of notopterygium root, cicada slough 2~4
Part, 1~3 part of radix glycyrrhizae.
Relative to the prior art, the Chinese medicine composition ratio that passes through preferred above component for the treatment of gout provided by the present invention
Chinese medicine preparation is made in example, and emplastrum is used in conjunction with oral formulations, makes to play synergistic effect between each component, windproof, righting, subtract
Poison, synergy, can preferably improve gout symptom and treatment gout.
Crotons skin disperse accumulation is stagnant, Toxin-Vanquishing, in herein described Chinese medicinal plaster can the turbid stasis of blood of letting out, so as to play treatment gout
Effect.
Monkshood acrid flavour, hardship, heat is very toxic, the thoughts of returning home, liver,kidney,spleen warp.Alkaloid in monkshood is mainly aconitine, middle crow
Aconine etc. under aconine and benzoyl, this kind of in head alkali, tower skill aconine, this outstanding aconine, benzoyl aconine, benzoyl
In the molecular structure of component, because of the acetylation and the hydroxyl aroylation of 14 of 8 hydroxyls, thus strong toxicity is presented, is river
Major toxicity component in crow.Monkshood can with dispelling wind and eliminating dampness, antalgic, for wind-cold-dampness arthralgia, arthralgia, trusted subordinate's crymodynia,
Cold hernia is had a pain, and can treat the illnesss such as wind-cold-dampness arthralgia, arthralgia.External application can stimulate skin, then produce feeling of numbness, therefore in pin
To being also used as analgestic in terms of gout.
Radix aconiti agrestis acrid flavour, hardship, property heat is very toxic, the thoughts of returning home, liver,kidney,spleen warp.Dispelling wind and eliminating dampness, antalgic are wet for chill
Numbness, arthralgia, trusted subordinate's crymodynia, cold hernia are had a pain and narcotic analgesic.Though radix aconiti agrestis is toxic, the Chinese medicine being used cooperatively with the emplastrum
Contain radix glycyrrhizae in oral formulations, have detoxication to radix aconiti agrestis.Alkaloid in radix aconiti agrestis has anesthetic effect and sedation, external application
Anodyne can be used as, alleviates feeling of pain caused by gout；In addition with cooling effect, alleviate the heating paresthesia of patient with gout.
Safflower taste is acrid in flavour and warm in nature, nontoxic, promoting blood circulation, stasis eliminatings analgesic.Control hemostasis to have a pain, carbuncle swells, injury from falling down.Herein described
Detumescence effect can be played in Chinese medicinal plaster.
Borneol is bitterly, tepor, nontoxic, and main scattered stagnated fire, the deep heat of energy, controls frightened epilepsy, phlegm confusing heart, larynx numbness, and tongue is swollen, toothache, also
Can myogenic pain relieving.
Edible oil can alleviate the skin irritatin sense of above-mentioned raw materials medicine, and help to form Transdermal absorption passage, promote to have
The absorption of component is imitated, so as to play drug effect.
Radix paeoniae rubrathe bitter, is slightly cold, return liver warp, clearing heat and cooling blood, removing blood stasis and analgesics, swells for febrile virulent maculae, hematemesis and epistaxis, hot eyes
Bitterly, liver-depressed hypochondrium pain, injury from falling down, carbuncle swells sore.The radix paeoniae rubrathe can purify the blood a point real heat, be good at promoting blood circulation to remove blood stasis.
Great burdock achene acrid flavour, hardship, cold in nature, distributed in lung channel, stomach, dispelling wind and heat from the body, facilitaing lung promoting eruption, subdhing swelling and detoxicating, belong under diaphoretic medicine
The cold-pungent and diaphoretic drugs of classification.Containing new burdock B prime, arctiin, arctigenin, arctigenin-4'-gentiobioside, linoleic acid, palmitic acid, stearic acid, flower
The components such as raw acid sugar.
Puncture vine acrid flavour, hardship, tepor is slightly poisonous, flat liver solution strongly fragrant, promoting blood circulation by removing wind, dehumidify, disappear carbuncle, available for rubella itch, carbuncle
Swell.
Windproof acrid flavour, sweet, slightly warm in nature, return bladder, lung, spleen, Liver Channel.Expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, stops convulsion, for diseases caused by external factors
Exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw just, the insufficiency of the spleen with overabundance of dampness etc..It is used cooperatively with notopterygium root, suitable for wind-cold-dampness arthralgia, podomere
Pain, Spasm of the tendons.
Duckweed acrid flavour, cold in nature, distributed in lung channel, dispelling wind-heat, promoting eruption, diuresis, for measles without adequate eruption, rubella itch, oedema urine
It is few etc..
Kuh-seng bitter, cold in nature, the thoughts of returning home, liver, stomach, large intestine, bladder warp.Heat-clearing and damp-drying drug, desinsection, diuresis, available for eczema, wet
Sore, mange leprosy etc..Matrine external application in kuh-seng has inhibitory action for swelling.
Schizonepeta acrid flavour, slight bitter, slightly warm in nature, wind-dispelling, inducing diaphoresis, promoting eruption, hemostasis, available for carbuncle swells, sore scabies etc..Schizonepeta is with anti-
Wind, can strengthen the effect of expelling pathogenic wind from the body surface.
Angelica sinensis tail is sweet in flavor, pungent, warm-natured, Return liver, the heart, the spleen channel, promoting blood circulation.Available for Amenorrhea is obstructed and hemostasis stagnates swelling and pain
Illness.Angelica sinensis tail is good at blood-breaking, there is the effect of promoting blood circulation and removing blood stasis, be usually used in treating Amenorrhea is obstructed, arthralgia and myalgia, numbness in hands and feet and
Hemostasis stagnate swelling and pain etc. disease, such as arthralgia pain due to rheumatism, ulcer sores etc..
It is dandelion bitter, sweet, it is cold in nature.It is clearing heat and detoxicating, diuresis dissipating bind.Available for boil poisonous soreness, fever.Closed with honeysuckle
With can strengthen antipyretic and antidote functions, can be used to ulcer serious case of furuncle, congestion and swelling pain.
Honeysuckle is sweet in flavor, cold in nature, enters lung, the heart, stomach, has effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treat wind, surname dissipate wind
Heat, is apt to removing summer-heat blood poison, and for various febrile diseases, such as body heat, dermexanthesis, hair spot, heat toxin sore carbuncle, abscess of throat disease, equal effect are shown
Write.Cure mainly disease under turgor, warm disease heating, the disease such as heat toxin large carbuncle and tumour.With the radix paeoniae rubrathe with use, have heat-clearing reason intestines, it is clearing heat and detoxicating,
Change the effect of stagnant and blood, available for damp and hot middle resistance, damage intestines network adipose membrane, diarrhea purulence blood, blood more than purulence, abdominal pain, tenesmus, high fever
Thirsty, dysphoria, or even coma and delirium.
Fructus Forsythiae bitter, it is cool, enter the heart, liver, gallbladder channel.Heat-clearing, removing toxic substances, dissipating bind, detumescence.Warm, erysipelas, macula are controlled, large carbuncle swells
Poison, scrofula, urine leaching closes.Shared with honeysuckle, antiphlogistic effects can be strengthened, and acted on clearing heat and detoxicating, expelling wind to resolve the exterior, can
It is micro- thirsty for warm disease initial stage, fever slight chill chill, mouth.
Notopterygium root acrid flavour；It is bitter；It is warm-natured.Return bladder, kidney channel.Cold dispelling expelling pathogenic factors from muscles and skin, wind-dispelling dampness elimination, numbness relieving and pain relieving, saturating extremities joint head
Mesh, all cold headaches, general joint pain are all suitable.The work(of its uplink diverging is stronger, kind to control head and upper limb joint pain.Notopterygium root with it is windproof
It is all Taiyang channel expelling wind drug, function is similar, and taste has preferable analgesic effect based on arduous；It is windproof inclined as length, notopterygium root to control wind
Wet in winning, two medicine phases must be to use, not only can expelling wind and clearing away cold, but also kind expel endogenous wind to relieve convulsion, fever with aversion to cold, headache caused by damp evil of catching cold
Body pain and arthralgia pain due to rheumatism etc. can be selected.Prove effective outstanding work for so-called " taiyang headache " after the inclined brain of pain.There is inducing diaphoresis with dandelion
Work(, Xiang Wuwei uses, one dissipate it is one clear, it is inside and outside with spouting, dissipate evil and detoxify, most imitated for moving back high fever.
Cicada slough is sweet in flavor, salty, cool in nature, return lung, Liver Channel.Dispelling wind and heat from the body, relieving sore-throat open sound, promoting eruption, removing nebula, Inflammation Zhijing.
For anemopyretic cold, warm disease from the beginning of, pharyngalgia hoarse voice, measles without adequate eruption, rubella itch, cataract, anxious chronic infantile convulsion, lockjaw card
Deng.It is equal with great burdock achene, honeysuckle, Fructus Forsythiae, puncture vine and uses, available for the effect for strengthening removing damp-heat.With schizonepeta, windproof, kuh-seng
It is equivalent to use, available for rheumatism contamination skin blood vessels, improve the diseases such as pruitus.
Radix glycyrrhizae is sweet and special, and gas is micro-, clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen etc..For weakness of the spleen and the stomach, lassitude hypodynamia, the heart
Throb with fear shortness of breath, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.Ulcer sores, Chang Yujin
Honeysuckle flower, Fructus Forsythiae are equally used, and play clearing heat and detoxicating work(altogether.With windproof with using, detoxication can be strengthened.With the radix paeoniae rubrathe with using, can show
Write the effect of contraction urgency pain is controlled in enhancing.
The embodiment of the present invention also provides a kind of preparation method of the Chinese medicine composition of above-mentioned treatment gout, the Chinese medicinal plaster
By the raw material through crushing, mixing；Peroral dosage form is made by the raw material in the oral preparation of Chinese traditional medicinal after decoction.
The preparation method process by crush, improve the specific surface area of medicine, be more advantageous to the precipitation of active ingredient, from
And preferably play drug effect；By decocting process, promote the active ingredient in medicine preferably to dissolve in solvent, improve decoction
The bioavilability of active ingredient in raw material, it is easier to absorb and play effect.
Specifically, the preparation method of the Chinese medicinal plaster specifically includes following steps：Each raw material group is weighed by raw material proportioning
Part, solid material is crushed, adds edible oil, is uniformly mixed, spreading is on carrier, to obtain the final product.
It is further preferred that described crush the bulk pharmaceutical chemicals specific surface area to crushed 100~200 mesh sieves, crushed through sieving
Larger, the active ingredient in medicine is more easy to dissolve in food oil, so as to play drug effect.
It is further preferred that the edible oil includes peanut oil and sesame oil.Both food oils are cheap and easy to get, and property
Stablize, medicine will not be hindered to play drug effect.The reconciliation of material powder is carried out for medium with oil, on the one hand emplastrum can be kept not do
It is dry, the passage to Transdermal absorption is on the other hand advantageously formed, active ingredient is more easy to percutaneous absorbtion, promotes the performance of drug effect.
It is further preferred that the edible oil is sesame oil, sesame oil is promoting absorption aspects better, and has and subtract
The effect of few medicine irritation, reduces the sense of discomfort of patient medication.
It is further preferred that the carrier includes non-woven fabrics, cotton, adhesive plaster, film, paste of the raw material grinding after reconciliation
Thing is coated on the carrier of softness, is easily affixed on skin, will not be come off because of the movement of limbs.
The preparation method of the oral preparation of Chinese traditional medicinal specifically includes following steps：Each material component is weighed by raw material proportioning,
Add water to cook 2~3 times, decoct 15~30 minutes every time, decoct water consumption every time as 3~5 times of material component gross mass, decoct
Collecting decoction afterwards.Repeatedly add water to cook on a small quantity, funneling effect can be formed in solution is decocted, promote active ingredient into solution
Release, improves the recovery rate to active ingredient.
It is further preferred that the peroral dosage form includes oral liquid, powder, capsule, tablet, granule, syrup, drop
Ball, is conventional oral dosage formulations, and preparation process is simple, is easy to take after being made, carries, and can improve it by the way that preparation is made
Taste, can improve facility and compliance that patient uses.
The embodiment of the present invention also provides application of the Chinese medicine composition of the treatment gout as treatment gout medicine.It is described
The application method of Chinese medicinal plaster in composition is：Emplastrum is affixed on the interior pass of upper arm, is made, Xinab, any in the most cave of hole
Any cave in one cave, or the ground machine of lower limb, grain leak, Sanyinjiao, 10~90 hours are wrapped up to sticking after sticking with preservative film
After the blistering of position, remove emplastrum, wash away medicine, puncturing bubble flows completely out liquid, until puncturing a mouthful Natural closure.
In order to better illustrate embodiment of the present invention, illustrated below by embodiment is further.
Embodiment 1
An embodiment of the present invention provides a kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and traditional Chinese medicine mouth system of mourning
Agent, the Chinese medicinal plaster include the raw material of following parts by weight proportioning：2 parts of crotons skin, 1 part of monkshood, 2 parts of radix aconiti agrestis, 3 parts of safflower,
0.1 part of borneol, 3 parts of peanut oil；The oral preparation of Chinese traditional medicinal includes the raw material of following parts by weight proportioning：3 parts of the radix paeoniae rubrathe, great burdock achene
2 parts, 1 part of puncture vine, 3 parts windproof, 4 parts of duckweed, 2 parts of kuh-seng, 4 parts of schizonepeta, 3 parts of Angelica sinensis tail, 2 parts of dandelion, 3 parts of honeysuckle, even
Stick up 2 parts, 3 parts of notopterygium root, 2 parts of cicada slough, 1 part of radix glycyrrhizae.
Preparation method：
Chinese medicinal plaster：The solid material medicine in the Chinese medicinal plaster is weighed by raw material proportioning, after crushed 100 mesh sieves, is added
Enter peanut oil to be uniformly mixed, be coated on non-woven fabrics, to obtain the final product；
Oral preparation of Chinese traditional medicinal：The bulk pharmaceutical chemicals of the oral preparation of Chinese traditional medicinal are weighed by raw material proportioning, add 3 times of water to decoct 15 minutes
Afterwards, filter, 3 times of water are added into the dregs of a decoction and are decocted 15 minutes, filtering, collecting decoction to obtain the final product；Made after decocting liquid is dried under reduced pressure
It is filling in No. 1 hard shell capsules into powder, up to capsule.
Application method：
By emplastrum be affixed on the interior pass of upper arm, make, Xinab, any cave in the most cave of hole, or the ground machine of lower limb, grain leak,
Any cave in Sanyinjiao, wraps up 10~90 hours to after sticking position blistering with preservative film after sticking, removes emplastrum, wash away
Medicine, puncturing bubble flows completely out liquid, until puncturing a mouthful Natural closure.
Oral preparation of Chinese traditional medicinal was taken points for 3 times in one day to be finished.
Embodiment 2
An embodiment of the present invention provides a kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and traditional Chinese medicine mouth system of mourning
Agent, the Chinese medicinal plaster include the raw material of following parts by weight proportioning：3 parts of crotons skin, 2 parts of monkshood, 4 parts of radix aconiti agrestis, 5 parts of safflower,
0.2 part of borneol, 4 parts of peanut oil；The oral preparation of Chinese traditional medicinal includes the raw material of following parts by weight proportioning：4 parts of the radix paeoniae rubrathe, great burdock achene
3 parts, 2 parts of puncture vine, 4 parts windproof, 6 parts of duckweed, 3 parts of kuh-seng, 6 parts of schizonepeta, 4 parts of Angelica sinensis tail, 3 parts of dandelion, 4 parts of honeysuckle, even
Stick up 4 parts, 4 parts of notopterygium root, 3 parts of cicada slough, 2 parts of radix glycyrrhizae.
Preparation method：
Chinese medicinal plaster：The solid material medicine in the Chinese medicinal plaster is weighed by raw material proportioning, after crushed 150 mesh sieves, is added
Enter sesame oil to be uniformly mixed, be coated on cotton, to obtain the final product；
Oral preparation of Chinese traditional medicinal：The bulk pharmaceutical chemicals of the oral preparation of Chinese traditional medicinal are weighed by raw material proportioning, add 4 times of water to decoct 25 minutes
Afterwards, filter, 4 times of water are added into the dregs of a decoction and are decocted 25 minutes, filtering, then add 4 times of water into the dregs of a decoction and decoct 25 minutes, filtering,
Collecting decoction to obtain the final product；Powder is made after decocting liquid is dried under reduced pressure, up to powder.
Application method is the same as embodiment 1.
Embodiment 3
An embodiment of the present invention provides a kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and traditional Chinese medicine mouth system of mourning
Agent, the Chinese medicinal plaster include the raw material of following parts by weight proportioning：5 parts of crotons skin, 3 parts of monkshood, 5 parts of radix aconiti agrestis, 6 parts of safflower,
0.3 part of borneol, 6 parts of peanut oil；The oral preparation of Chinese traditional medicinal includes the raw material of following parts by weight proportioning：5 parts of the radix paeoniae rubrathe, great burdock achene
4 parts, 3 parts of puncture vine, 5 parts windproof, 8 parts of duckweed, 4 parts of kuh-seng, 8 parts of schizonepeta, 5 parts of Angelica sinensis tail, 4 parts of dandelion, 5 parts of honeysuckle, even
Stick up 5 parts, 5 parts of notopterygium root, 4 parts of cicada slough, 3 parts of radix glycyrrhizae.
Preparation method：
Chinese medicinal plaster：The solid material medicine in the Chinese medicinal plaster is weighed by raw material proportioning, after crushed 200 mesh sieves, is added
Enter sesame oil to be uniformly mixed, be coated on film, to obtain the final product；
Oral preparation of Chinese traditional medicinal：The bulk pharmaceutical chemicals of the oral preparation of Chinese traditional medicinal are weighed by raw material proportioning, add 5 times of water to decoct 30 minutes
Afterwards, filter, 5 times of water are added into the dregs of a decoction and are decocted 30 minutes, filtering, collecting decoction to obtain the final product；Made after decocting liquid is dried under reduced pressure
Into powder, after adding auxiliary material (20wt% microcrystalline celluloses, 15wt% Ac-Di-Sols, 0.5wt% magnesium stearates)
Tabletting, up to tablet.
Application method is the same as embodiment 1.
Clinical test
Subjects：Patient with gout totally 50, men and women is fifty-fifty, and the age is 30~45 years old.
Test material：The Chinese medicine composition of the gained treatment gout of embodiment 2.Application method is pasted with embodiment 1, wherein emplastrum
Take position to make choice with the gout breaking-out position of each patient, be affixed on the acupuncture point nearest apart from gout breaking-out position.
After taking 30 days, using pain, swelling, fever as observation index, clinical test results are counted, are shown in Table 1.
1 Symptom Observation table of table
By above clinical testing data as it can be seen that the Chinese medicine composition for the treatment gout that the embodiment of the present invention 2 is provided with
When patient with gout, gout symptom can be significantly improved, so as to improve the quality of life of patient.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modification, equivalent substitution or improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of Chinese medicine composition for treating gout, including Chinese medicinal plaster and oral preparation of Chinese traditional medicinal, it is characterised in that：
The Chinese medicinal plaster includes the raw material of following parts by weight proportioning：2~5 parts of crotons skin, 1~3 part of monkshood, radix aconiti agrestis 2~5
Part, 3~6 parts of safflower, 0.1~0.3 part of borneol, 3~6 parts of edible oil；
The oral preparation of Chinese traditional medicinal includes the raw material of following parts by weight proportioning：3~5 parts of the radix paeoniae rubrathe, 2~4 parts of great burdock achene, puncture vine 1
~3 parts, 3~5 parts windproof, 4~8 parts of duckweed, 2~4 parts of kuh-seng, 4~8 parts of schizonepeta, 3~5 parts of Angelica sinensis tail, 2~4 parts of dandelion,
3~5 parts of honeysuckle, 2~5 parts of Fructus Forsythiae, 3~5 parts of notopterygium root, 2~4 parts of cicada slough, 1~3 part of radix glycyrrhizae.
A kind of 2. preparation method of the Chinese medicine composition of the treatment gout described in claim 1, it is characterised in that：The Traditional Chinese medicine plaster
Cream is by the raw material through crushing, mixing；Peroral dosage form is made by the raw material in the oral preparation of Chinese traditional medicinal after decoction.
3. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 2, it is characterised in that the Traditional Chinese medicine plaster
The preparation method of cream specifically includes following steps：Each material component is weighed by raw material proportioning, solid material is crushed, is added edible
Oil, is uniformly mixed, and spreading is on carrier, to obtain the final product.
4. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 3, it is characterised in that the crushing is
It crushed 100~200 mesh sieves.
5. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 3, it is characterised in that the edible oil
Including peanut oil and sesame oil.
6. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 5, it is characterised in that the edible oil
For sesame oil.
7. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 3, it is characterised in that the carrier bag
Include non-woven fabrics, cotton, adhesive plaster, film.
8. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 2, it is characterised in that the traditional Chinese medicine mouth
The preparation method of formulation specifically includes following steps：Each material component is weighed by raw material proportioning, adds water to cook 2~3 times, every time
Decoct 15~30 minutes, decoct water consumption every time as 3~5 times of material component gross mass, collecting decoction after decoction.
9. the preparation method of the Chinese medicine composition for the treatment of gout according to claim 2, it is characterised in that the oral agents
Type includes oral liquid, powder, capsule, tablet, granule, syrup, dripping pill.
10. application of the Chinese medicine composition of gout as treatment gout medicine is treated described in claim 1.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101897767A (en) * | 2010-07-26 | 2010-12-01 | 浙江中医药大学 | Urarthritis lavipeditum powder |
| CN105878598A (en) * | 2014-12-25 | 2016-08-24 | 袁锦乾 | External traditional Chinese medicinal tincture for treating gout |
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2017
- 2017-12-13 CN CN201711323809.8A patent/CN107929376A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101897767A (en) * | 2010-07-26 | 2010-12-01 | 浙江中医药大学 | Urarthritis lavipeditum powder |
| CN105878598A (en) * | 2014-12-25 | 2016-08-24 | 袁锦乾 | External traditional Chinese medicinal tincture for treating gout |
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| 秦泗锋: "蠲痹汤加减配合四妙散外敷治疗痛风性关节炎54例", 《中国现代药物应用》 * |
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