CN107921053B - 用于治疗或预防干眼症的方法 - Google Patents

用于治疗或预防干眼症的方法 Download PDF

Info

Publication number
CN107921053B
CN107921053B CN201680035333.5A CN201680035333A CN107921053B CN 107921053 B CN107921053 B CN 107921053B CN 201680035333 A CN201680035333 A CN 201680035333A CN 107921053 B CN107921053 B CN 107921053B
Authority
CN
China
Prior art keywords
dry eye
general formula
compound
eye
tear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201680035333.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN107921053A (zh
Inventor
吴荣灿
洪琳雅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN107921053A publication Critical patent/CN107921053A/zh
Application granted granted Critical
Publication of CN107921053B publication Critical patent/CN107921053B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201680035333.5A 2015-06-16 2016-06-16 用于治疗或预防干眼症的方法 Active CN107921053B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562180450P 2015-06-16 2015-06-16
US62/180,450 2015-06-16
PCT/CN2016/000309 WO2016201953A1 (en) 2015-06-16 2016-06-16 Method for treating or preventing dry eyes

Publications (2)

Publication Number Publication Date
CN107921053A CN107921053A (zh) 2018-04-17
CN107921053B true CN107921053B (zh) 2020-09-01

Family

ID=57544797

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680035333.5A Active CN107921053B (zh) 2015-06-16 2016-06-16 用于治疗或预防干眼症的方法

Country Status (9)

Country Link
US (1) US10383885B2 (enExample)
EP (1) EP3310361B1 (enExample)
JP (1) JP6960399B2 (enExample)
KR (1) KR102606948B1 (enExample)
CN (1) CN107921053B (enExample)
AU (1) AU2016279139B2 (enExample)
CA (1) CA2989341C (enExample)
TW (1) TWI649083B (enExample)
WO (1) WO2016201953A1 (enExample)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332726A (zh) 1998-11-02 2002-01-23 卫福有限公司 吡咯烷化合物及其药物用途
CA2383971A1 (en) 1999-09-06 2001-03-15 Hiroaki Naka Prophylactic and therapeutic medicaments for ophthalmic diseases
CN1257176C (zh) * 2003-10-24 2006-05-24 广州中医药大学热带医学研究所 2，3，5，4＇－四羟基二苯乙烯－2－O－β－D－葡萄糖苷在制备降血脂药物中的应用
US20060292099A1 (en) * 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
US20100160243A1 (en) 2008-12-24 2010-06-24 National Yang-Ming University Compounds and methods for enhancing erythropoiesis
CN101966193B (zh) * 2010-10-29 2012-05-23 西南交通大学 2,3,5,4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷在制备治疗抑郁症药物中的应用
US20120164242A1 (en) * 2010-12-27 2012-06-28 Wen-Jen Yu Novel methods for modulating melanin production
CN105188688A (zh) * 2013-03-28 2015-12-23 吴淑芬 用于在非造血性细胞中诱导促红细胞生成素(epo)介导的产生血红蛋白表达和线粒体生物合成的组合物和方法
CN103524576A (zh) * 2013-08-12 2014-01-22 天津中医药大学 2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的分离纯化工艺

Also Published As

Publication number Publication date
KR20180019151A (ko) 2018-02-23
CA2989341A1 (en) 2016-12-22
EP3310361B1 (en) 2022-05-11
US20180193369A1 (en) 2018-07-12
AU2016279139B2 (en) 2020-09-10
US10383885B2 (en) 2019-08-20
AU2016279139A1 (en) 2018-01-04
WO2016201953A1 (en) 2016-12-22
CA2989341C (en) 2021-12-07
CN107921053A (zh) 2018-04-17
TWI649083B (zh) 2019-02-01
JP2018517776A (ja) 2018-07-05
EP3310361A4 (en) 2019-01-23
KR102606948B1 (ko) 2023-11-27
EP3310361A1 (en) 2018-04-25
TW201717965A (zh) 2017-06-01
JP6960399B2 (ja) 2021-11-05

Similar Documents

Publication Publication Date Title
Cholkar et al. Topical delivery of aqueous micellar resolvin E1 analog (RX-10045)
CN104661663A (zh) 用于眼部疾病和病症的组合物和治疗
KR20130099926A (ko) 염증성 눈질환의 치료/예방용 화합물
KR102578102B1 (ko) 엔도텔린 수용체 길항제의 국소 안용 제형
US10010586B2 (en) Method of treating intraocular tissue pathologies with nerve growth factor
WO2016208961A1 (ko) 이마티닙을 유효성분으로 포함하는 안구 건조 질환 예방 및 치료용 약학 조성물
WO2020231670A1 (en) Triamcinolone acetonide-loaded liposomes topical ophthalmic formulations for prevention of macular thickening and its associated visual outcomes after lens surgery
Cagini et al. Kinetics of hydrocortisone sodium phosphate penetration into the human aqueous humor after topical application
JP7637430B2 (ja) 新規な眼球乾燥症治療用薬学的組成物
TWI649083B (zh) 用於治療或預防乾眼症的方法
JP2023518179A (ja) ドライアイ疾患、網膜変性疾患、又は眼の炎症の治療のための抗老化グリコペプチドの使用
US20250360185A1 (en) Compositions comprising pedf-derived short peptides for the treatment of dry eye diseases
WO2025140240A1 (zh) 一种用于治疗和/或预防角膜损伤的药物组合物和方法
CN118717959A (zh) Pedf多肽模拟物在眼表疾病中的用途
Polak Drugs used in ocular treatment

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant