KR102606948B1 - 안구 건조증을 치료하거나 예방하는 방법 - Google Patents

안구 건조증을 치료하거나 예방하는 방법 Download PDF

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Publication number
KR102606948B1
KR102606948B1 KR1020187000291A KR20187000291A KR102606948B1 KR 102606948 B1 KR102606948 B1 KR 102606948B1 KR 1020187000291 A KR1020187000291 A KR 1020187000291A KR 20187000291 A KR20187000291 A KR 20187000291A KR 102606948 B1 KR102606948 B1 KR 102606948B1
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South Korea
Prior art keywords
dry eye
formula
compound
eye
ngf
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KR1020187000291A
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English (en)
Korean (ko)
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KR20180019151A (ko
Inventor
롱-쭌 우
린-예 홍
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롱-쭌 우
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Publication of KR102606948B1 publication Critical patent/KR102606948B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020187000291A 2015-06-16 2016-06-16 안구 건조증을 치료하거나 예방하는 방법 Active KR102606948B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562180450P 2015-06-16 2015-06-16
US62/180,450 2015-06-16
PCT/CN2016/000309 WO2016201953A1 (en) 2015-06-16 2016-06-16 Method for treating or preventing dry eyes

Publications (2)

Publication Number Publication Date
KR20180019151A KR20180019151A (ko) 2018-02-23
KR102606948B1 true KR102606948B1 (ko) 2023-11-27

Family

ID=57544797

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187000291A Active KR102606948B1 (ko) 2015-06-16 2016-06-16 안구 건조증을 치료하거나 예방하는 방법

Country Status (9)

Country Link
US (1) US10383885B2 (enExample)
EP (1) EP3310361B1 (enExample)
JP (1) JP6960399B2 (enExample)
KR (1) KR102606948B1 (enExample)
CN (1) CN107921053B (enExample)
AU (1) AU2016279139B2 (enExample)
CA (1) CA2989341C (enExample)
TW (1) TWI649083B (enExample)
WO (1) WO2016201953A1 (enExample)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1332726A (zh) 1998-11-02 2002-01-23 卫福有限公司 吡咯烷化合物及其药物用途
CA2383971A1 (en) 1999-09-06 2001-03-15 Hiroaki Naka Prophylactic and therapeutic medicaments for ophthalmic diseases
CN1257176C (zh) * 2003-10-24 2006-05-24 广州中医药大学热带医学研究所 2，3，5，4＇－四羟基二苯乙烯－2－O－β－D－葡萄糖苷在制备降血脂药物中的应用
US20060292099A1 (en) * 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
US20100160243A1 (en) 2008-12-24 2010-06-24 National Yang-Ming University Compounds and methods for enhancing erythropoiesis
CN101966193B (zh) * 2010-10-29 2012-05-23 西南交通大学 2,3,5,4’-四羟基二苯乙烯-2-O-β-D-葡萄糖苷在制备治疗抑郁症药物中的应用
US20120164242A1 (en) * 2010-12-27 2012-06-28 Wen-Jen Yu Novel methods for modulating melanin production
CN105188688A (zh) * 2013-03-28 2015-12-23 吴淑芬 用于在非造血性细胞中诱导促红细胞生成素(epo)介导的产生血红蛋白表达和线粒体生物合成的组合物和方法
CN103524576A (zh) * 2013-08-12 2014-01-22 天津中医药大学 2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷的分离纯化工艺

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Antonio Abengózar-Vela et al. Quercetin and Resveratrol Decrease the Inflammatory and Oxidative Responses in Human Ocular Surface Epithelial Cells. Biochemistry and Molecular Bilogy, v.56 pp.2709-2719

Also Published As

Publication number Publication date
KR20180019151A (ko) 2018-02-23
CA2989341A1 (en) 2016-12-22
EP3310361B1 (en) 2022-05-11
CN107921053B (zh) 2020-09-01
US20180193369A1 (en) 2018-07-12
AU2016279139B2 (en) 2020-09-10
US10383885B2 (en) 2019-08-20
AU2016279139A1 (en) 2018-01-04
WO2016201953A1 (en) 2016-12-22
CA2989341C (en) 2021-12-07
CN107921053A (zh) 2018-04-17
TWI649083B (zh) 2019-02-01
JP2018517776A (ja) 2018-07-05
EP3310361A4 (en) 2019-01-23
EP3310361A1 (en) 2018-04-25
TW201717965A (zh) 2017-06-01
JP6960399B2 (ja) 2021-11-05

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