CN107913309A - The method of the total brass of high efficiency extraction bitter buckwheat seed - Google Patents
The method of the total brass of high efficiency extraction bitter buckwheat seed Download PDFInfo
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- CN107913309A CN107913309A CN201711213963.XA CN201711213963A CN107913309A CN 107913309 A CN107913309 A CN 107913309A CN 201711213963 A CN201711213963 A CN 201711213963A CN 107913309 A CN107913309 A CN 107913309A
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- bitter buckwheat
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The method that the present invention discloses the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：(1) after the bitter buckwheat seed of collection is cleaned up, drying to constant weight, crushed 80 mesh sieves and is placed at shady and cool drying, spare；(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:25~1:35g/ml adds the ethanol extractant that volume fraction is 50~60%, is placed in the ultrasonic cleaner that power is 200W, 45~55min is extracted at a temperature of 45~55 DEG C；(3) extracting solution is collected, separation takes supernatant, is freeze-dried after evaporation and concentration, up to first product.Extracting method of the present invention is simple, easily operated, extraction cost is low, under preferred process extraction conditions, the yield of general flavone is 7.852%, recovery rate is high, and do not destroy active ingredient, organic solvent-free residual, the utilization rate of sweet potato stem leaf is effectively improved, so that bitter buckwheat maximum benefit, is adapted to industrialized production.
Description
Technical field
The present invention relates to the extracting method of natural goods, and in particular to the method for the total brass of high efficiency extraction bitter buckwheat seed.
Background technology
Bitter buckwheat, that is, duck wheat, scientific name hull buckwheat, alias buckwheat leaf seven, wild blue buckwheat, Wan Nianqiao, spinach wheat, black wheat, Hua Qiao.Than
The nutritive value of sweet tea buckwheat, that is, buckwheat is higher by very much.The content of particularly bioflavonoid is 13.5 times of buckwheat.Bitter buckwheat seven is sought greatly
Foster element rolls into one completely, is not medicine, is not health products, is that can work as the food that meal is eaten, the healthy nutritive value for but having brilliance
With outstanding dietotherapy effect.It does not belong to grass family, and belongs to polygonaceae, and polygonaceae is belonged to together with " fleece-flower root, rheum officinale " familiar to people etc.,
It is typical case's embodiment of China's integration of drinking and medicinal herbs culture.Bitter buckwheat is known as " kings of five cereals ", and three drop food (blood pressure lowering, it is hypoglycemic, blood drops
Fat).Nutrition unique, comprehensively, abundant that bitter buckwheat possesses, and medicinal characteristic is good, a variety of nutrition necessary to having human body into
Part.Bitter buckwheat has the effect of catharsis and toxin expelling, among the people and be called " net intestines grass ".Bitter buckwheat can be to make tea-drinking after frying, daily drink
There is auxiliary therapeutic action with to the three high patients.Bitter buckwheat is medicine-food two-purpose crop very few in nature, according to《Compendium of Materia Medica》Record：
Bitter buckwheat bitter, cold, the real stomach of energy, benefiting energy, continues spirit, sharp knowledge, it is dirty to refine the five internal organs slag；《Qianjin Yao Fang》、《Chinese medicine is big
Dictionary》It is and all on the books to bitter buckwheat in pertinent literature：Can calm the nerves, swell wind pain, productization of dispelling of lively atmosphere blood, the wide intestines of sending down abnormally ascending, heat-clearing it is stagnant, clear
Intestines, ease constipation, defaecation, cough-relieving, relieving asthma, anti-inflammatory, antiallergy, cardiac stimulant, weight-reducing, beauty and other effects.
Flavones is also referred to as flavone, is widely present in nature, particularly in plant, due to the flavonoid found at first
Thing all has a ketone carbonyl group structure, and is in yellow or faint yellow, therefore claims flavones.Bioflavonoid is that have relatively strong remove certainly
By base and the kind material of oxidation resistance, the antioxidation of some bioflavonoids is even several times as much as vitamin C, dimension life
Plain E.And numerous bioflavonoids does not have bioactivity then because of the difference of its structure, some performance bioactives, some.It is bitter
Buckwheat seed is the accessory substance of bitter buckwheat process, rich in plant flavone, but this part resource and not up to rational utilization at present, from
And the effective rate of utilization of bitter buckwheat is low, and then reduce the benefit of bitter buckwheat resource.
The content of the invention
In view of the deficiencies of the prior art, the object of the present invention is to provide a kind of cost is low, method is simple, it is easy to operate, carry
The method for taking the high total brass of high efficiency extraction bitter buckwheat seed of rate, this extracting method do not destroy active ingredient, organic solvent-free residual, can
Make bitter buckwheat resource greatest benefit.
In order to achieve the above object, the present invention adopts the technical scheme that：
The method of the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, until dry untill constant weight,
Dried bitter buckwheat seed, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:25~1:35g/ml adds the ethanol that volume fraction is 50~60%
Extractant, is placed in the ultrasonic cleaner that power is 200W, 45~55min is extracted at a temperature of 45~55 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, takes supernatant, it is cold after evaporation and concentration
It is lyophilized dry, up to the general flavone first product of sweet potato stem leaf.
It is yellow to be conducive to improve in order to make the flavones in bitter buckwheat seed be fully dissolved in ethanol as optimal technical scheme
The recovery rate and purity of ketone, the preferable volume fraction of ethanol is 55% in the step (2).
It is yellow to be conducive to improve in order to make the flavones in bitter buckwheat seed be fully dissolved in ethanol as optimal technical scheme
The recovery rate and purity of ketone, while the waste of resource is avoided, bitter buckwheat powder of seeds and the preferable solid-liquid ratio of ethanol in the step (2)
For 1：30g/ml.
As optimal technical scheme, in order to make the flavones in bitter buckwheat seed leaf be fully dissolved in ethanol, be conducive to improve yellow
The recovery rate and purity of ketone, while extraction cost is effectively controlled, preferable ultrasonic extraction temperature is 50 DEG C in the step (2).
As optimal technical scheme, in order to as far as possible all extract the flavones in bitter buckwheat seed, so as to obtain higher flavones
Recovery rate and purity, while effectively control extraction cost, the preferable ultrasonic extraction time is 50min in the step (2).
Beneficial effects of the present invention：Extracting method of the present invention is simple, easily operated, extraction cost is low, in ethanol volume integral
Number is 55%, solid-liquid ratio 1：30g/ml, ultrasonic extraction temperature are 50 DEG C, ultrasonic extraction time 50min, ultrasonic power 200W
Under preferred process extraction conditions, the yield of general flavone is 7.852%, and recovery rate is high, and does not destroy active ingredient, organic solvent-free
Residual, effectively improves the utilization rate of bitter buckwheat, so that bitter buckwheat maximum benefit, is adapted to industrialized production.
Embodiment
The present invention is further described with reference to specific embodiment.
Embodiment 1
The method of the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, until dry untill constant weight,
Dried bitter buckwheat seed, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:25g/ml adds the ethanol extractant that volume fraction is 50%, is placed in
Power is in the ultrasonic cleaner of 200W, and 45min is extracted at a temperature of 45 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, takes supernatant, it is cold after evaporation and concentration
Lyophilized dry, up to the general flavone first product of sweet potato stem leaf, the yield of general flavone is 7.798%.
Embodiment 2
The method of the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, until dry untill constant weight,
Dried bitter buckwheat seed, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:27g/ml adds the ethanol extractant that volume fraction is 52%, is placed in
Power is in the ultrasonic cleaner of 200W, and 47min is extracted at a temperature of 47 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, takes supernatant, it is cold after evaporation and concentration
Lyophilized dry, up to the general flavone first product of sweet potato stem leaf, the yield of general flavone is 7.821%.
Embodiment 3
The method of the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, until dry untill constant weight,
Dried bitter buckwheat seed, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:30g/ml adds the ethanol extractant that volume fraction is 50%, is placed in
Power is in the ultrasonic cleaner of 200W, and 50min is extracted at a temperature of 50 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, takes supernatant, it is cold after evaporation and concentration
Lyophilized dry, up to the general flavone first product of sweet potato stem leaf, the yield of general flavone is 7.852%.
Embodiment 4
The method of the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, until dry untill constant weight,
Dried bitter buckwheat seed, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:32g/ml adds the ethanol extractant that volume fraction is 57%, is placed in
Power is in the ultrasonic cleaner of 200W, and 52min is extracted at a temperature of 52 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, takes supernatant, it is cold after evaporation and concentration
Lyophilized dry, up to the general flavone first product of sweet potato stem leaf, the yield of general flavone is 7.834%.
Embodiment 5
The method of the total brass of high efficiency extraction bitter buckwheat seed, comprises the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, until dry untill constant weight,
Dried bitter buckwheat seed, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:35g/ml adds the ethanol extractant that volume fraction is 60%, is placed in
Power is in the ultrasonic cleaner of 200W, and 55min is extracted at a temperature of 55 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, takes supernatant, it is cold after evaporation and concentration
Lyophilized dry, up to the general flavone first product of sweet potato stem leaf, the yield of general flavone is 7.796%.
It should be pointed out that above case is only the representational example of the present invention.Obviously, technical scheme and unlimited
In above-described embodiment, there can also be many denaturation.
Claims (5)
1. the method for the total brass of high efficiency extraction bitter buckwheat seed, it is characterised in that comprise the following steps：
(1) after the bitter buckwheat seed of collection is cleaned up, drying in thermostatic drying chamber is placed in, it is dry until dry untill constant weight
Bitter buckwheat seed afterwards, which is put into pulverizer, is ground into powder, is positioned over after crossing 80 mesh sieves at shady and cool drying, spare；
(2) it is 1 by solid-liquid ratio to bitter buckwheat powder of seeds:25~1:35g/ml adds the ethanol that volume fraction is 50~60% and extracts
Agent, is placed in the ultrasonic cleaner that power is 200W, 45~55min is extracted at a temperature of 45~55 DEG C；
(3) after treating ultrasonic extraction, extracting solution is collected, carries out suction filtration centrifugation, taken supernatant, freezed after evaporation and concentration dry
It is dry, up to the general flavone first product of sweet potato stem leaf.
2. the method for the total brass of high efficiency extraction bitter buckwheat seed according to claim 1, it is characterised in that：In the step (2)
The preferable volume fraction of ethanol is 55%.
3. the method for the total brass of high efficiency extraction bitter buckwheat seed according to claim 2, it is characterised in that：In the step (2)
Bitter buckwheat powder of seeds is 1 with the preferable solid-liquid ratio of ethanol：30g/ml.
4. the method for the total brass of high efficiency extraction bitter buckwheat seed according to claim 3, it is characterised in that：In the step (2)
Preferable ultrasonic extraction temperature is 50 DEG C.
5. the method for the total brass of high efficiency extraction bitter buckwheat seed according to claim 4, it is characterised in that：In the step (2)
The preferable ultrasonic extraction time is 50min.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112239710A (en) * | 2019-07-19 | 2021-01-19 | 四川酩创酒科技有限公司 | Total flavone extract and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1965915A (en) * | 2006-11-11 | 2007-05-23 | 山西医科大学 | Method for extracting bitter buckwheat flavone in high purity |
| CN104069187A (en) * | 2014-07-24 | 2014-10-01 | 劲牌生物医药有限公司 | Technological method extracting duckwheat flavone from duckwheat |
| CN106822254A (en) * | 2017-04-06 | 2017-06-13 | 桂林实力科技有限公司 | The ultrasonic extraction process of general flavone is extracted from tartary buckwheat shell |
-
2017
- 2017-11-28 CN CN201711213963.XA patent/CN107913309A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1965915A (en) * | 2006-11-11 | 2007-05-23 | 山西医科大学 | Method for extracting bitter buckwheat flavone in high purity |
| CN104069187A (en) * | 2014-07-24 | 2014-10-01 | 劲牌生物医药有限公司 | Technological method extracting duckwheat flavone from duckwheat |
| CN106822254A (en) * | 2017-04-06 | 2017-06-13 | 桂林实力科技有限公司 | The ultrasonic extraction process of general flavone is extracted from tartary buckwheat shell |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112239710A (en) * | 2019-07-19 | 2021-01-19 | 四川酩创酒科技有限公司 | Total flavone extract and preparation method and application thereof |
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Application publication date: 20180417 |
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