CN109730315A - A kind of rhizoma polygonati edible mushroom oral solution and preparation method thereof that is antifatigue, improving immunity - Google Patents

A kind of rhizoma polygonati edible mushroom oral solution and preparation method thereof that is antifatigue, improving immunity Download PDF

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CN109730315A
CN109730315A CN201910165935.8A CN201910165935A CN109730315A CN 109730315 A CN109730315 A CN 109730315A CN 201910165935 A CN201910165935 A CN 201910165935A CN 109730315 A CN109730315 A CN 109730315A
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rhizoma polygonati
water
mushroom
parts
added
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张娥珍
梁晓君
蓝桃菊
黄振勇
淡明
王冬梅
黄梅华
韦馨平
何全光
黄茂康
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Guangxi Zhuang Nationality Autonomous Region Academy of Agricultural Sciences
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Guangxi Zhuang Nationality Autonomous Region Academy of Agricultural Sciences
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Abstract

The invention discloses a kind of antifatigue, improve the rhizoma polygonati edible mushroom oral solution and preparation method thereof of immunity, the oral solution uses myrtle fruit, Hericium erinaceus, cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, the pure natural food materials of Phellinus are as raw material, extract concentration, obtain extracting solution, it is equipped with rhizoma polygonati nano powder again, carry out homogeneous, sterilizing, it is filling etc., it is formed to have and improves immunity, the rhizoma polygonati edible mushroom oral solution of anti-fatigue effect, also there is certain enriching the blood and tonifying qi, enriching yin and nourishing kidney, the effects of moistening lung and producing body fluid, its is applied widely, men and women, old and young are all drinkable.Preparation method of the present invention is simple to operation, environmentally protective, can carry out industrialized production.

Description

A kind of rhizoma polygonati edible mushroom oral solution and preparation method thereof that is antifatigue, improving immunity
Technical field
The present invention relates to food processing technology field, specifically a kind of rhizoma polygonati edible mushroom mouthful that is antifatigue, improving immunity Take liquid and preparation method thereof.
Background technique
The wild HUANGJING ZANYU CAPSULE germ plasm resource in China is abundant, and reserves are huge, because collecting medicinal, edible, ornamental, beauty , market demand increasingly increases, with good economic efficiency.Modern pharmacology research thinks that rhizoma polygonati has disease-resistant original Microorganism, reducing blood lipid, blood glucose, anti-aging, the effect for improving learning and memory reproduction, can enhance human immunity, and increase The activity of strong superoxide dismutase in vivo, can slow down body aging.Therefore, it deeply develops rhizoma polygonati to be added in field of food, tool There is good development prospect.
Edible mushroom refers to that fructification is very large, gill fungus bacterium (macro fungi) that can be edible, and edible mushroom known to China has more than 350 Kind, wherein belong to Basidiomycotina more.The domestic fungus resource of China is abundant, and cultivation earliest, using one of country of edible mushroom, The features such as edible mushroom is not only delicious, but also has high protein, and low fat is low in calories, high-drug-effect is the generally acknowledged nutrition in the world today Health food.Scientific research proves that edible mushroom contains very high nutrient value and health care effect, often edible, can supplement body Element needed for body maintains balance.It has effects that medicine, plays a role in health care for human body, raw by raw material of edible mushroom Health food, health care oral liquid, wine and the drug for producing processing are largely used to medicinal and investment health-product market.With the modern times The consumption habit of the promotion of people's living standard, people is changing.How Chinese common people are from how to have enough to eat Transformation also increases severely for the pursuit of health-nutrition food with day.Therefore, edible mushroom is increasingly subject to various countries as a kind of green food The attention of the people.
It is less as the development and application of health food for rhizoma polygonati at present, the also seldom of edible mushroom oral solution is processed, Large-scale production has not yet been formed, oral solution in the market is also mostly to deploy, and containing multiple additives, more drinks are unfavorable for people Body health.
Summary of the invention
The object of the present invention is to provide a kind of rhizoma polygonati edible mushroom oral solution and preparation method thereof, which uses hill gooseberry The pure natural food materials such as fruit, Hericium erinaceus, cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, Phellinus as raw material, Concentration is extracted, extracting solution is obtained, then is equipped with rhizoma polygonati nano powder, carries out homogeneous, sterilizing, filling etc., is formed to have to improve and be exempted from The rhizoma polygonati edible mushroom oral solution of epidemic disease power, anti-fatigue effect also there is certain enriching the blood and tonifying qi, enriching yin and nourishing kidney, moistening lung and producing body fluid etc. to make With.
The invention is realized by the following technical scheme:
A kind of rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, the raw material including following parts by weight: rhizoma polygonati 40~60 Part, it is 15~30 parts of myrtle fruit, 20~30 parts of Hericium erinaceus, 2~5 parts of cordyceps sinensis, 5~10 parts of tremella, 10~20 parts of agaric, fragrant 10~20 parts of mushroom, 5~8 parts of Cordyceps militaris, 5~8 parts of Poria cocos, 5~10 parts of umbellate pore furgus, 4~8 parts of Phellinus.
The rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, preparation method includes the following steps:
(1) feedstock processing
Rhizoma polygonati: rhizoma polygonati is cleaned up, and is impregnated 5~10 minutes with 0.1~0.2% citric acid solution, is rinsed well with clear water, is dripped It is dry;It is dry to be no more than 6% to moisture content, granularity is crushed to no more than 200nm with disintegrating apparatus to get rhizoma polygonati nano powder;
Myrtle fruit: choosing fresh hill gooseberry's ripening fruits without chemical contamination, free from insect pests, removes impurity, dries in the air after cleaning up Dry surface moisture is ground, centrifugal filtration, obtains filtrate;Filter residue is taken, 2~3 times of water is added and impregnates 30~60min, was centrifuged Filter merges filtrate twice, a small amount of ascorbic acid is added, obtains hill gooseberry's juice;
Hericium erinaceus: by Hericium erinaceus crushed after being dried, crossing 50~80 meshes, the water of 10~20 times of its weight be added, impregnate 1~2h, Be ultrasonically treated 2~3 times, every time 10~15min with 2000~3000W, after filtering filtrate, be concentrated into primary liquid volume 20~ 30% to get hedgehog hydnum mushroom extracting solution;
Cordyceps sinensis: the water of 10~20 times of its weight, 20~40min of small fire infusion are added after crushing;
Tremella: tremella is placed in 2~6h of immersion in clear water, drains 0.5~1h of holding in the water vapour for be placed on 80~100 DEG C; Then physical squeezing is carried out under the conditions of 15~25 DEG C, makes to be separated by solid-liquid separation, and gained liquid is tremella extract;
Agaric: crushed 30~50 meshes for agaric dry product, the water of 20~40 times of its weight be added, under the conditions of 80~100 DEG C Auricularia auriculajudae powder is extracted 1~3 hour, with 25~40KHz ultrasonication 3~5 times, 10~20min, is filtered while hot every time, then Supernatant is collected in centrifuge separation, is concentrated into the 10~20% of primary liquid volume to get edible tree fungi extracting liquid;
Mushroom: crushed 30~50 meshes for mushroom dry product, the water of 10~20 times of its weight be added, under the conditions of 90~100 DEG C Mushroom powder is extracted 1~2 hour, is ultrasonically treated 2~3 times with 80~100W, 5~10min, is filtered while hot every time, is then centrifuged for Supernatant is collected in separation, is concentrated into the 40~50% of primary liquid volume to get mushroom extract;
Cordyceps militaris: being added the water of 10~20 times of its weight after crushing, in 80~90 DEG C circumfluence distillation 3 times, every time 80~90 Min obtains filtrate, is concentrated into the 30~40% of primary liquid volume to get Cordyceps militaris extracting solution after filtering;
Poria cocos: being added the water of 10~20 times of its weight after crushing, in 80~90 DEG C circumfluence distillation 3 times, every time 2~3h, filtering Filtrate is obtained afterwards, is concentrated into the 30~40% of primary liquid volume to get Poria cocos extracting solution;
Umbellate pore furgus: crushed 20~30 meshes for umbellate pore furgus, and the water of 7~12 times of its weight is added, impregnates 20 under the conditions of 90~100 DEG C ~24 hours, 7~9h is extracted with Soxhlet extractor, the filtrate of suction filtration is concentrated into the 20~30% of primary liquid volume to get umbellate pore furgus Extracting solution;
Phellinus: being added the water of 40~50 times of its weight after crushing, in 50~60 DEG C of 0.04~0.07MPa of vacuum degree, water temperature conditions 2~3h of lower extraction;Centrifuge separation collects supernatant, is concentrated into the 10~20% of primary liquid volume to get Phellinus extracting solution;
(2) ingredient, homogeneous: by Hericium erinaceus, the extraction of cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, Phellinus Liquid is uniformly mixed, and rhizoma polygonati nano powder and hill gooseberry's juice is added, and carries out homogeneous with homogenizer, homogenization pressure is 40~50Mpa;
(3) it sterilizes: 121~125 DEG C of sterilization temperature, sterilizing time 8~10 seconds;
(4) filling: hot filling temperature is 85~88 DEG C, after the completion of filling, is inverted, is cooled to room temperature immediately, as finished product.
Rhizoma polygonati (scientific name:Polygonatum sibiricum), also known as: polygonatum sibiricum Redoute, yellow chicken dish, pen tube dish, claw ginseng, Tendrilleaf solomonseal rhizome, achickenclaw ginseng;For the rhizome of Liliaceae HUANGJING ZANYU CAPSULE.Rhizoma polygonati is medicinal plant, not only can be used as medicine, but also can eat Object;With tonifying spleen, the effect of moistening lung and producing body fluid.Rhizoma polygonati is mild-natured, sweet in flavor, eats tasty and refreshing, and meat rhizomes is plump, forms sediment containing a large amount of Powder, sugar, fat, protein, carrotene, vitamin and various other nutritional ingredients, eat raw, stewing can allay one's hunger and Body-building is used, and can make us that strength multiplication, muscle is full, marrow is strong, highly beneficial to body.Modern pharmacology research thinks yellow Essence has the function of resisting pathogenic microbes, reducing blood lipid, blood glucose, anti-aging, improves learning and memory reproduction, can enhance people Body immunity, the activity of superoxide dismutase in reinforcement, can slow down body aging.It is oligomeric containing rhizoma polygonati in rhizoma polygonati rhizome A variety of elements needed by human such as sugar, Siberian solomonseal rhizome polysaccharide, flavonoids, quinones, lymphatic temperament, amino acid.Oligosaccharide is conducive to improve people Body enteron aisle biotic environment, is proliferated profitable strain, the infringement for reducing and inhibiting harmful substance to human body;Flavone compound is to height The symptoms such as headache, dizziness caused by blood pressure have obvious curative effects, have apparent anti-inflammatory, anti-ulcer effect and hypoglycemic, antioxygen The effects of change, anti-mutability, anti-aging, protection nervous system, improvement memory.
Hill gooseberry (Classification system:Rhodomyrtus tomentosa), alias: Myrtaceae, Myrtus shrub are trembled Buddhist nun, hilllock M.-dodecandrum, mountain M.-dodecandrum, Duo Lian, when pears root, harvest subtree, beans are harvested, secondary Buddhist nun, black belly, peach uncle (mother's brother) ma, when mud etc., 2 meters of Gao Keda.It is mature Fruit is edible, can also make wine, and is the Natural Food source of birds, is afforestation, improvement of the ecological environment, is that green, water and soil conservation is answered on hillside Evergreen shrubs.Its fruit has invigorating the spleen benefit blood, convergence removing toxic substances, controls enterogastritis, internal lesion caused by overexertion, dysentery, function promoting blood circulation and removing obstruction in channels, astringing to arrest diarrhea Effect.Hill gooseberry's fruit contains more comprehensive nutritional ingredient, wherein containing crude fat 7.97%, crude protein 6.21%, crude fibre 34.97%, lignin 31.76%, total reducing sugar 18.53t%, reduced sugar 15.52%, vitamin C 28.8%, biotin 10.19mg/ 100g, S- carrotene 0.388mg/100g, more there is the minerals of amino acid abundant and a variety of needed by human body, and fruit contains flavones Class, phenolic constituent, amino acid and carbohydrate.Hill gooseberry is pure natural wild fruit, no chemical fertilizer and pollution by pesticides, belongs to 1st generation exploitation Fruit, the effect of enriching blood, convergent curative effect, diarrhoea can also be prevented and treated, meet current consumer " return from So " psychology of exploitation consumption green food requires, and is a kind of high rich manganese plant, and value medical health care is very high, hill gooseberry Supplement source of the food as Organic Manganese, to prevent liver cancer, the diseases such as hepatitis are of great significance.
Hericium erinaceus (scientific name:Hericium erinaceus) it is called Hericium erinaceus, hedgehog hydnum mushroom, hedgehog bacterium, hedgehog bacterium, monkey mushroom, be A kind of rotten edible mushroom of wood, the fungi of dual-purpose of drug and food, meat tenderness, taste are fragrant, tasty, are put into one of eight big mountains delicacy.Fructification is in Bulk, flat hemispherical or capitiform, meat, 5~15cm of diameter, not branch;It is white when fresh, become brown or light brown when dry Color;Fructification base portion is narrow or slightly short handle.The nutritional ingredient of Hericium erinaceus is very high, contains volatile oil, protein, polysaccharide, amino The ingredients such as acid, are high protein, low fat, the food rich in minerals and vitamins, in addition also rich in various vitamins and inorganic Salt.Chinese medicine thinks that Hericium erinaceus is sweet natured, have relieving the five internal organs, it is aid digestion, nourish the body and other effects, also there is enhancing gastric mucosa screen Hinder function, improves lymphocyte transformation rate, promotes the effects of human immunological competence.Clinical application shows that Hericium erinaceus can be treated and disappears Change the diseases such as bad, gastric ulcer, antral gastritis, stomachache, gasteremphraxis and neurasthenia.Suitable for people of all ages, elderly and infirm eats Hericium erinaceus, There is nourishing and fit keeping function.
Cordyceps sinensis is also known as cordyceps sinensis or cordyceps, be Clavicipitaceae plant aweto (Cordyceps sinensis( BerK.)Sacc.) parasitic stroma and larva on the larvae of batrachidae insects corpse complex.Mainly Active constituent is the substance that cordycepin, cordycepic acid, Cordyceps sinensis polysaccharide etc. are beneficial to absorption of human body, have adjust function of immune system, The multiple efficacies such as antifatigue.Cordyceps sinensis is the traditional rare medicated nourishing product in China, it is sweet natured, has tonifying lung kidney, stops Cough, benefit is deficient, supports the function of vital essence.According to clinical research, cordyceps sinensis has with ten big functions supports lung yin, kidney tonifying Positive, relieving cough and reducing sputum, anticancer prevents old effect, and for the product of flat tonifying yin sun, men and women, old and young can be eaten, and is the benefit for being suitble to crowd most wide Product have greatly a help to body, mend marrow benefit lung kidney, and pharmacological property is mild, can not make one to generate like ginseng scorching, there is the benefit of ginseng And the evil without ginseng.
Agaric (Classification system:Auricularia auricula (L.ex Hook.)Underwood) agaric both can be wild It can cultivate again, kind fructification is in ear shaped, lobate or cup-shaped, thin, edge is wavy, 3-10 centimetres wide, thick 2 millimeters of left sides It is right.Agaric is sweet in flavor, mild-natured, has many medicinal efficacies, being divided to from color has tremella and two kinds of black fungus.
Agaric, that is, black fungus of general address, black fungus also known as black dish, mulberry ear, this bacterium, tree chicken, the wooden moth, wood are fine and soft, black wood Not only meat is fine and smooth for ear, crisp smooth mouth and full of nutrition, containing protein, fat, carbohydrate and multivitamin and Inorganic salts, nutriment contained by black fungus, some are apparently higher than other foods, and the content of its protein is equivalent to meat, Vitamin B2 content is more than rice, face, vegetables and meat, and iron content is 100 times higher than meat, and calcium content is 30~70 times of meat, The various nutrition as contained by black fungus are improved and are enriched, and " meat or fish in element " is known as.Auricularia polysaccharide in black fungus exempts from body Epidemic disease function is obviously promoted effect, including increases spleen index, half times of hemolysis value and red rose pigment rate, and macrophage is promoted to gulp down Function and lymphocyte transformation rate are bitten, Cellular Immunity and humoral immune function are increased, there is significant and anti-tumor activity;Its After carrotene enters human body, it is transformed into vitamin A, there is moist skin and hair;Lecithin can make internal rouge in vivo Fat is in liquid matter state, is conducive to fat and completely consumes in vivo, drives body fat movement, keeps Fat Distribution reasonable, body is even Claim.
Tremella (scientific name:Tremella) it is also referred to as tremella, tremella, tremella etc., belong to Mycophyta Tremellaceae Tremella, It is a fructification for Basidiomycota fungi tremella, there is the laudatory title of " hat in bacterium ".Tremella fructification is pure white to milky, diameter 5 ~10cm, soft pure white, translucent, high resilience.Tremella is sweet in flavor, light, mild-natured, nontoxic;Contain protein, fat and a variety of Amino acid, minerals and glycogen have strong essence, kidney tonifying, ease constipation, beneficial stomach, tonifying Qi and blood, heart tonifying, strong body, cerebrum tonifying, refresh oneself, beauty Appearance, tender skin, the effect of promoting longevity can improve liver detoxification ability, protect liver function;It can also enhance human immunity, increase Tolerance of the strong tumor patient to Radiotherapy chemotherapy.Tremella has the function of enriching yin rich in natural plant colloid, additional its, and being can With the good moisturizing food of long-term use.
Mushroom (scientific name:Lentinus edodes (Berk.)sing) also known as flower mushroom, mushroom, fragrant letter, fragrant bacterium, dried mushroom, perfume (or spice) Wild rice is the fructification of Pleurotaceae plant mushroom.Mushroom is one of second-biggest-in-the-world edible mushroom and China's specialty, in civil element There is the title of " mountain delicacy ".Mushroom delicious flavour, fragrance make people mentally refreshing is full of nutrition, be high protein, low fat, polysaccharide, a variety of amino acid and Multivitamin nutritional health food, rich in vitamin B, provitamin D, iron, potassium etc..Lentinan (β -1,3 glucan) Cell immunocompetent can be enhanced, inhibit the growth of cancer cell;Mushroom contains more than 40 kinds of enzymes, can correct human chitinase deficiency disease;It is fragrant It is beneficial to reduce blood lipid to human body for fatty institute's fatty acids in mushroom.
Cordyceps militaris (scientific name:Cordyceps militaris) be Ascomycota, meat seat mesh, Clavicipitaceae, Cordyceps mould Formula kind.It is had shown that through research, the Cordyceps militaris medicine clinical effectiveness manually cultivated is identical as natural cordyceps sinensis, can equally adjust Whole body function, the phagocytic function for improving immunocompetence, enhancing macrophage, the formation for promoting antibody are saved, mainly has and protects lung kidney-nourishing Nourishing the liver, the wrinkle resistant anti-aging of moisturizing, antimicrobial antiphlogistic, calmness, expansion blood vessel, reduces blood pressure, reduces blood glucose, is anti-at relieving cough and asthma eliminating the phlegm The effects of fatigue, resist oxygen lack.Cordyceps militaris is widely used in health food and nourishing food, modern science demonstration section young pilose antler Cordyceps militaris Not only there is special nutritive value, but also have apparent medical value, a large amount of cordycepin, Cordyceps sinensis polysaccharide are contained in Cordyceps militaris Cordycepic acid and cordyceps sinensis SOD, wherein Cordyceps sinensis polysaccharide is the generally acknowledged human immunity reinforcing agent of International Medical.
Poria cocos be polyporaceae fungus (Poria cocos(Schw.)Wolf) dry sclerotia.It is adopted in 7~September It digs, removes silt after digging out, after banking up " sweating ", spread out and dry in the air to dry tack free, then " sweating ", be repeated several times to existing wrinkle, interior It after moisture big portion in portion's scatters and disappears, dries in the shade, referred to as " Poria cocos ";Or fresh Poria cocos is pressed into different parts cutting, it dries in the shade, is referred to as " Fu Siberian cocklebur block " and " Indian buead tablet ".Poria cocos is mild-natured, and taste is done light, has effects that Li Shui, detumescence, clearing damp, strengthening the spleen and stomach.
Umbellate pore furgus (scientific name:polyporus) it is Aphyllophorales Polyporaceae Ramalina medicinal fungi.Fructification is big or very big, Meat has handle, multi-branched, the raw circular white in end to light brown cap.Alias: Zhu Ling, pig zero, Jia pig dung, pig bag, Sima Biao, pig Siberian cocklebur, black peach, wild boar food, polyporus umbellatus, pig Poria cocos, wild boar excrement.Nature and flavor are flat, sweet, light.There is the effect of diuresis, excreting dampness; Grifola polysaccharide rich in umbellate pore furgus, has the function of Immune-enhancing effect, in recent years it has also been found that having the function of anticancer.
Phellinus is On Polyporaceae phelliuns igniariusPhellinus igniarius (L. ex Fr.) Quel.Son Entity is born in alias on the broad leaf trees trunk such as poplar, willow: parasitism, Sang Chen, tree chicken, white heart-rot fungus, Phellinus wild rice, Phellinus mushroom, needle layer on mulberry Pore fungi, Japanese apricot bacterium.Have effects that promoting blood circulation, hemostasis, change drink, antidiarrheal, also there is immunoregulatory effect.
The present invention makes full use of rhizoma polygonati and multiple eating bacterium natural material to process, science extract edible fungi polysaccharide, amino acid, The plurality of active ingredients such as vitamin change edible mushroom tradition looks, make a kind of health care's drink, also can be convenient people Drink at any time.
Beneficial effects of the present invention:
1, the rhizoma polygonati edible mushroom oral solution not only delicious flavour prepared by the present invention, and it is full of nutrition, by a variety of natural edibles Bacterium and rhizoma polygonati are prepared, and most of nutritional ingredients of raw material are remained in preparation process, and remove undesirable constituents therein, make The oral solution of preparation has health-care effect that is antifatigue well and improving immunity, also has enriching the blood and tonifying qi, enriching yin and nourishing kidney, profit The effects of lung fluid.
2, the present invention is using the advantages of nanometer rhizoma polygonati powder: the full broken wall of cell keeps original life after crushing to rhizoma polygonati raw material Object characteristic, nanometer rhizoma polygonati powder, which only needs the short time to impregnate, can just be such that effective ingredient oozes out, and greatly improve the utilization of raw material Rate significantly improves absorption of human body effect, improves bioavailability.
3, it is also added into hill gooseberry's juice in the present invention, has effects that promoting blood circulation and removing obstruction in channels, astringing to arrest diarrhea, it is edible to enhance rhizoma polygonati The health-care effect of fungus oral liquid, hill gooseberry's juice contain certain natural pigment, natural dyeing can be carried out to oral solution, without addition The food additives such as toner and essence, it is healthy and safe, drink in good taste, applied widely, men and women, old and young are all drinkable.
4, present invention process is simple to operation, environmentally protective, can carry out industrialized production.
Specific embodiment
In order to keep technical solution of the present invention and advantage clearer, below with reference to the embodiment of the present invention, to the present invention Technical solution be clearly and completely described.
Embodiment 1
A kind of rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, the raw material including following parts by weight: 40 parts of rhizoma polygonati, 15 parts of myrtle fruit, 20 parts of Hericium erinaceus, 2 parts of cordyceps sinensis, 5 parts of tremella, 10 parts of agaric, 10 parts of mushroom, 5 parts of Cordyceps militaris, Poria cocos 5 Part, 5 parts of umbellate pore furgus, 4 parts of Phellinus.
The rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, preparation method includes the following steps:
(1) feedstock processing
Rhizoma polygonati: rhizoma polygonati is cleaned up, and is impregnated 10 minutes with 0.1% citric acid solution, is rinsed well, drained with clear water;It is dry It is no more than 6% to moisture content, is crushed to granularity no more than 200nm to get rhizoma polygonati nano powder with disintegrating apparatus;
Myrtle fruit: choosing fresh hill gooseberry's ripening fruits without chemical contamination, free from insect pests, removes impurity, dries in the air after cleaning up Dry surface moisture is ground, centrifugal filtration, obtains filtrate;Filter residue is taken, 2 times of water is added and impregnates 50min, centrifugal filtration merges A small amount of ascorbic acid is added in filtrate twice, obtains hill gooseberry's juice;
Hericium erinaceus: by Hericium erinaceus crushed after being dried, crossing 50 meshes, the water of 20 times of its weight be added, impregnate 2h, with 2000W ultrasound Processing 2 times, each 15min obtains filtrate, is concentrated into the 20% of primary liquid volume to get hedgehog hydnum mushroom extracting solution after filtering;
Cordyceps sinensis: the water of 10 times of its weight, small fire infusion 20min are added after crushing;
Tremella: tremella being placed in clear water and impregnates 2h, is drained in the water vapour for be placed on 100 DEG C and is kept 0.5h;Then in 20 DEG C Under the conditions of carry out physical squeezing, make to be separated by solid-liquid separation, gained liquid is tremella extract;
Agaric: crushed 50 meshes for agaric dry product, and the water of 20 times of its weight is added, to auricularia auriculajudae powder extraction 3 under the conditions of 80 DEG C Hour, with 40KHz ultrasonication 3 times, each 20min is filtered while hot, is then centrifuged for separating, and is collected supernatant, is concentrated into original The 20% of liquid volume is to get edible tree fungi extracting liquid;
Mushroom: crushed 30 meshes for mushroom dry product, and the water of 10 times of its weight is added, to mushroom powder extraction 2 under the conditions of 90 DEG C Hour, it is ultrasonically treated 3 times with 80W, each 10min is filtered while hot, is then centrifuged for separating, and is collected supernatant, is concentrated into primary liquid The 40% of volume is to get mushroom extract;
Cordyceps militaris: being added the water of 15 times of its weight after crushing, in 85 DEG C circumfluence distillation 3 times, every time 90 min, after filtering Filtrate is concentrated into the 35% of primary liquid volume to get Cordyceps militaris extracting solution;
Poria cocos: being added the water of 12 times of its weight after crushing, in 85 DEG C circumfluence distillation 3 times, each 2h, after filtering filtrate, it is dense The 30% of primary liquid volume is reduced to get Poria cocos extracting solution;
Umbellate pore furgus: crushed 20 meshes for umbellate pore furgus, and the water of 12 times of its weight is added, and impregnates 20 hours under the conditions of 90 DEG C, uses Soxhlet Extractor extracts 9h, and the filtrate of suction filtration is concentrated into the 20% of primary liquid volume to get umbellate pore furgus extracting solution;
Phellinus: being added the water of 40 times of its weight after crushing, extracts 3h under the conditions of vacuum degree 0.04MPa, 60 DEG C of water temperature;Centrifugation point From collection supernatant is concentrated into the 10% of primary liquid volume to get Phellinus extracting solution;
(2) ingredient, homogeneous: by Hericium erinaceus, the extraction of cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, Phellinus Liquid is uniformly mixed, and rhizoma polygonati nano powder and hill gooseberry's juice is added, carries out homogeneous, homogenization pressure 40Mpa with homogenizer;
(3) it sterilizes: 121 DEG C of sterilization temperature, sterilizing time 8 seconds;
(4) filling: hot filling temperature is 85 DEG C, after the completion of filling, is inverted, is cooled to room temperature immediately, as finished product.
Embodiment 2
A kind of rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, the raw material including following parts by weight: 50 parts of rhizoma polygonati, 24 parts of myrtle fruit, 25 parts of Hericium erinaceus, 4 parts of cordyceps sinensis, 7 parts of tremella, 15 parts of agaric, 15 parts of mushroom, 6 parts of Cordyceps militaris, Poria cocos 6 Part, 6 parts of umbellate pore furgus, 6 parts of Phellinus.
The rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, preparation method includes the following steps:
(1) feedstock processing
Rhizoma polygonati: rhizoma polygonati is cleaned up, and is impregnated 10 minutes with 0.15% citric acid solution, is rinsed well, drained with clear water;It is dry It is no more than 6% to moisture content, is crushed to granularity no more than 200nm to get rhizoma polygonati nano powder with disintegrating apparatus;
Myrtle fruit: choosing fresh hill gooseberry's ripening fruits without chemical contamination, free from insect pests, removes impurity, dries in the air after cleaning up Dry surface moisture is ground, centrifugal filtration, obtains filtrate;Filter residue is taken, 3 times of water is added and impregnates 30min, centrifugal filtration merges A small amount of ascorbic acid is added in filtrate twice, obtains hill gooseberry's juice;
Hericium erinaceus: by Hericium erinaceus crushed after being dried, crossing 80 meshes, the water of 10 times of its weight be added, impregnate 1h, with 3000W ultrasound Processing 3 times, each 10min obtains filtrate, is concentrated into the 30% of primary liquid volume to get hedgehog hydnum mushroom extracting solution after filtering;
Cordyceps sinensis: the water of 15 times of its weight, small fire infusion 50min are added after crushing;
Tremella: tremella being placed in clear water and impregnates 4h, is drained in the water vapour for be placed on 90 DEG C and is kept 1h;Then in 20 DEG C of conditions Lower carry out physical squeezing, makes to be separated by solid-liquid separation, gained liquid is tremella extract;
Agaric: crushed 30~50 meshes for agaric dry product, and the water of 30 times of its weight is added, and soak under the conditions of 90 DEG C to auricularia auriculajudae powder It mentions 2 hours, with 30KHz ultrasonication 5 times, each 15min is filtered while hot, is then centrifuged for separating, and collects supernatant, concentration To primary liquid volume 15% to get edible tree fungi extracting liquid;
Mushroom: crushed 50 meshes for mushroom dry product, and the water of 20 times of its weight is added, to mushroom powder extraction 1 under the conditions of 100 DEG C Hour, it is ultrasonically treated 2 times with 90W, each 8min is filtered while hot, is then centrifuged for separating, and is collected supernatant, is concentrated into primary liquid The 40% of volume is to get mushroom extract;
Cordyceps militaris: being added the water of 20 times of its weight after crushing, in 80 DEG C circumfluence distillation 3 times, every time 90 min, after filtering Filtrate is concentrated into the 30% of primary liquid volume to get Cordyceps militaris extracting solution;
Poria cocos: being added the water of 20 times of its weight after crushing, in 85 DEG C circumfluence distillation 3 times, each 3h, after filtering filtrate, it is dense The 40% of primary liquid volume is reduced to get Poria cocos extracting solution;
Umbellate pore furgus: crushed 30 meshes for umbellate pore furgus, and the water of 10 times of its weight is added, and impregnates 22 hours under the conditions of 100 DEG C, uses Soxhlet Extractor extracts 8h, and the filtrate of suction filtration is concentrated into the 25% of primary liquid volume to get umbellate pore furgus extracting solution;
Phellinus: being added the water of 45 times of its weight after crushing, extracts 3h under the conditions of vacuum degree 0.05MPa, 55 DEG C of water temperature;Centrifugation point From collection supernatant is concentrated into the 15% of primary liquid volume to get Phellinus extracting solution;
(2) ingredient, homogeneous: by Hericium erinaceus, the extraction of cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, Phellinus Liquid is uniformly mixed, and rhizoma polygonati nano powder and hill gooseberry's juice is added, carries out homogeneous, homogenization pressure 45Mpa with homogenizer;
(3) it sterilizes: 121 DEG C of sterilization temperature, sterilizing time 10 seconds;
(4) filling: hot filling temperature is 85 DEG C, after the completion of filling, is inverted, is cooled to room temperature immediately, as finished product.
Embodiment 3
A kind of rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, the raw material including following parts by weight: 60 parts of rhizoma polygonati, 30 parts of myrtle fruit, 30 parts of Hericium erinaceus, 5 parts of cordyceps sinensis, 10 parts of tremella, 20 parts of agaric, 20 parts of mushroom, 8 parts of Cordyceps militaris, Fu 8 Part, 10 parts of umbellate pore furgus, 8 parts of Phellinus.
The rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, preparation method includes the following steps:
(1) feedstock processing
Rhizoma polygonati: rhizoma polygonati is cleaned up, and is impregnated 10 minutes with 0.2% citric acid solution, is rinsed well, drained with clear water;It is dry It is no more than 6% to moisture content, is crushed to granularity no more than 200nm to get rhizoma polygonati nano powder with disintegrating apparatus;
Myrtle fruit: choosing fresh hill gooseberry's ripening fruits without chemical contamination, free from insect pests, removes impurity, dries in the air after cleaning up Dry surface moisture is ground, centrifugal filtration, obtains filtrate;Filter residue is taken, 3 times of water is added and impregnates 60min, centrifugal filtration merges A small amount of ascorbic acid is added in filtrate twice, obtains hill gooseberry's juice;
Hericium erinaceus: by Hericium erinaceus crushed after being dried, crossing 60 meshes, the water of 15 times of its weight be added, impregnate 1h, with 3000W ultrasound Processing 2 times, each 15min obtains filtrate, is concentrated into the 20% of primary liquid volume to get hedgehog hydnum mushroom extracting solution after filtering;
Cordyceps sinensis: the water of 20 times of its weight, small fire infusion 40min are added after crushing;
Tremella: tremella being placed in clear water and impregnates 6h, is drained in the water vapour for be placed on 80 DEG C and is kept 1h;Then in 15 DEG C of conditions Lower carry out physical squeezing, makes to be separated by solid-liquid separation, gained liquid is tremella extract;
Agaric: crushed 30 meshes for agaric dry product, and the water of 40 times of its weight is added, to auricularia auriculajudae powder extraction 2 under the conditions of 100 DEG C Hour, with 25KHz ultrasonication 4 times, each 10min is filtered while hot, is then centrifuged for separating, and is collected supernatant, is concentrated into original The 20% of liquid volume is to get edible tree fungi extracting liquid;
Mushroom: crushed 50 meshes for mushroom dry product, and the water of 15 times of its weight is added, to mushroom powder extraction 2 under the conditions of 98 DEG C Hour, it is ultrasonically treated 2 times with 100W, each 5min is filtered while hot, is then centrifuged for separating, and is collected supernatant, is concentrated into primary liquid The 40% of volume is to get mushroom extract;
Cordyceps militaris: being added the water of 10 times of its weight after crushing, in 80 DEG C circumfluence distillation 3 times, 80 min, must filter after filtering every time Liquid is concentrated into the 40% of primary liquid volume to get Cordyceps militaris extracting solution;
Poria cocos: being added the water of 20 times of its weight after crushing, in 88 DEG C circumfluence distillation 3 times, each 2h, after filtering filtrate, it is dense The 30% of primary liquid volume is reduced to get Poria cocos extracting solution;
Umbellate pore furgus: crushed 30 meshes for umbellate pore furgus, and the water of 12 times of its weight is added, and impregnates 24 hours under the conditions of 100 DEG C, uses Soxhlet Extractor extracts 7h, and the filtrate of suction filtration is concentrated into the 20% of primary liquid volume to get umbellate pore furgus extracting solution;
Phellinus: being added the water of 50 times of its weight after crushing, extracts 3h under the conditions of vacuum degree 0.07MPa, 60 DEG C of water temperature;Centrifugation point From collection supernatant is concentrated into the 10% of primary liquid volume to get Phellinus extracting solution;
(2) ingredient, homogeneous: by Hericium erinaceus, the extraction of cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, Phellinus Liquid is uniformly mixed, and rhizoma polygonati nano powder and hill gooseberry's juice is added, carries out homogeneous, homogenization pressure 50Mpa with homogenizer;
(3) it sterilizes: 121 DEG C of sterilization temperature, sterilizing time 10 seconds;
(4) filling: hot filling temperature is 88 DEG C, after the completion of filling, is inverted, is cooled to room temperature immediately, as finished product.
The oral solution prepared in the embodiment of the present invention is subjected to following mouse experiment:
Experiment mice is divided into 4 groups, every group 8, male and female each 4, wherein one group as a control group, three groups are experimental group, experiment Group is outer in normal raising, daily feeding oral solution of the invention, and control group is except normal raising, daily feeding distilled water;Feeding Time is one month.
Test 1 group: daily noon feeding is primary, and each amount is 2ml;Test 2 groups: each feeding is primary sooner or later daily, Each amount is 2ml;Test 3 groups: daily feeding each in the morning, afternoon and evening is primary, and each amount is 2ml;Control group: in daily morning The distilled water of evening each feeding 2ml.Adaptability swimming training is carried out to mouse daily during feeding, the training time: the last fortnight is every Its 20min, behind daily 30min.
After one month feeding training time, swimming contest is carried out to mouse, Jiangnan mouse is placed in the swimming trunk of 40cm depth In, it is arranged 30 ± 2 DEG C of water temperature, in the object block of one mouse own wt 8% of tail system of mouse, forces mouse in swimming pool Swimming is exhausted to power, i.e., mouse sinks under water 5 seconds and do not float, and records time, the as swimming time of mouse.Calculate every group The average swimming time of mouse, the time is longer, and the anti-fatigue ability for illustrating mouse is stronger, and statistical experiment result is as follows: control Group 8.5min, tests 1 group of 12.4min, tests 2 groups of 14.8min, tests 3 group 17,2min.The experimental results showed that 3 groups of experiment Mouse swimming time longest, one times of the time more than control group, i.e., after feeding oral solution of the invention, resisting for mouse is tired Labor ability is significantly improved.
After continuous feeding oral solution of the invention, mouse is placed in the environment of faint germ one week, control group mice Illness rate is 50%, and test group mouse illness rate is 10%, it is seen then that the mouse illness rate of feeding oral solution is substantially reduced, and illustrates it Immunity is improved.

Claims (2)

1. a kind of rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity, it is characterised in that: the original including following parts by weight Material: 40~60 parts of rhizoma polygonati, 15~30 parts of myrtle fruit, 20~30 parts of Hericium erinaceus, 2~5 parts of cordyceps sinensis, 5~10 parts of tremella, wood 10~20 parts of ear, 10~20 parts of mushroom, 5~8 parts of Cordyceps militaris, 5~8 parts of Poria cocos, 5~10 parts of umbellate pore furgus, 4~8 parts of Phellinus.
2. rhizoma polygonati edible mushroom oral solution that is antifatigue, improving immunity according to claim 1, it is characterised in that: it is made Preparation Method the following steps are included:
(1) feedstock processing
Rhizoma polygonati: rhizoma polygonati is cleaned up, and is impregnated 5~10 minutes with 0.1~0.2% citric acid solution, is rinsed well with clear water, is dripped It is dry;It is dry to be no more than 6% to moisture content, granularity is crushed to no more than 200nm with disintegrating apparatus to get rhizoma polygonati nano powder;
Myrtle fruit: choosing fresh hill gooseberry's ripening fruits without chemical contamination, free from insect pests, removes impurity, dries in the air after cleaning up Dry surface moisture is ground, centrifugal filtration, obtains filtrate;Filter residue is taken, 2~3 times of water is added and impregnates 30~60min, was centrifuged Filter merges filtrate twice, a small amount of ascorbic acid is added, obtains hill gooseberry's juice;
Hericium erinaceus: by Hericium erinaceus crushed after being dried, crossing 50~80 meshes, the water of 10~20 times of its weight be added, impregnate 1~2h, Be ultrasonically treated 2~3 times, every time 10~15min with 2000~3000W, after filtering filtrate, be concentrated into primary liquid volume 20~ 30% to get hedgehog hydnum mushroom extracting solution;
Cordyceps sinensis: the water of 10~20 times of its weight, 20~40min of small fire infusion are added after crushing;
Tremella: tremella is placed in 2~6h of immersion in clear water, drains 0.5~1h of holding in the water vapour for be placed on 80~100 DEG C; Then physical squeezing is carried out under the conditions of 15~25 DEG C, makes to be separated by solid-liquid separation, and gained liquid is tremella extract;
Agaric: crushed 30~50 meshes for agaric dry product, the water of 20~40 times of its weight be added, under the conditions of 80~100 DEG C Auricularia auriculajudae powder is extracted 1~3 hour, with 25~40KHz ultrasonication 3~5 times, 10~20min, is filtered while hot every time, then Supernatant is collected in centrifuge separation, is concentrated into the 10~20% of primary liquid volume to get edible tree fungi extracting liquid;
Mushroom: crushed 30~50 meshes for mushroom dry product, the water of 10~20 times of its weight be added, under the conditions of 90~100 DEG C Mushroom powder is extracted 1~2 hour, is ultrasonically treated 2~3 times with 80~100W, 5~10min, is filtered while hot every time, is then centrifuged for Supernatant is collected in separation, is concentrated into the 40~50% of primary liquid volume to get mushroom extract;
Cordyceps militaris: being added the water of 10~20 times of its weight after crushing, in 80~90 DEG C circumfluence distillation 3 times, every time 80~90 Min obtains filtrate, is concentrated into the 30~40% of primary liquid volume to get Cordyceps militaris extracting solution after filtering;
Poria cocos: being added the water of 10~20 times of its weight after crushing, in 80~90 DEG C circumfluence distillation 3 times, every time 2~3h, filtering Filtrate is obtained afterwards, is concentrated into the 30~40% of primary liquid volume to get Poria cocos extracting solution;
Umbellate pore furgus: crushed 20~30 meshes for umbellate pore furgus, and the water of 7~12 times of its weight is added, impregnates 20 under the conditions of 90~100 DEG C ~24 hours, 7~9h is extracted with Soxhlet extractor, the filtrate of suction filtration is concentrated into the 20~30% of primary liquid volume to get umbellate pore furgus Extracting solution;
Phellinus: being added the water of 40~50 times of its weight after crushing, in 50~60 DEG C of 0.04~0.07MPa of vacuum degree, water temperature conditions 2~3h of lower extraction;Centrifuge separation collects supernatant, is concentrated into the 10~20% of primary liquid volume to get Phellinus extracting solution;
(2) ingredient, homogeneous: by Hericium erinaceus, the extraction of cordyceps sinensis, tremella, agaric, mushroom, Cordyceps militaris, Poria cocos, umbellate pore furgus, Phellinus Liquid is uniformly mixed, and rhizoma polygonati nano powder and hill gooseberry's juice is added, and carries out homogeneous with homogenizer, homogenization pressure is 40~50Mpa;
(3) it sterilizes: 121~125 DEG C of sterilization temperature, sterilizing time 8~10 seconds;
(4) filling: hot filling temperature is 85~88 DEG C, after the completion of filling, is inverted, is cooled to room temperature immediately, as finished product.
CN201910165935.8A 2019-03-06 2019-03-06 A kind of rhizoma polygonati edible mushroom oral solution and preparation method thereof that is antifatigue, improving immunity Pending CN109730315A (en)

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