CN107898705A - It is a kind of can pre- anti-caries and canker sore mouthwash and preparation method thereof - Google Patents
It is a kind of can pre- anti-caries and canker sore mouthwash and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention belongs to oral health technical field, and in particular to it is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：5 10 parts of catechin, 5 10 parts of vine polyphenol, 15 20 parts of gingerol, 8 15 parts of chamomile hydrosol, 38 parts of vitamin C, 4 10 parts of folic acid, 13 parts of sweetener, 15 20 parts of Chinese medical extract, 10 20 parts of tea extract.Mouthwash of the present invention is made of pure natural raw material; it is safe and healthy, nontoxic, daily nursing articles for use long-time service can be used as, can effectively remove the bacterium in cavity; the effect of preferable pre- anti-caries and canker sore is played, and long-time service is to human body generation without any side effects.
Description
Technical field
The invention belongs to oral health technical field, and in particular to it is a kind of can pre- anti-caries and canker sore mouthwash and
Its preparation method.
Background technology
With the continuous improvement of people's living standards, more and more people start to focus on oral health, wherein carious tooth and mouth
Chamber ulcer is most common mouth disease.Carious tooth is bacteriosis, therefore it can be with secondary pulpitis and periapical inflammation, even
Alveolar bone and inflammation of jaws can be caused, the scabies secondary infection of carious tooth can form lesion, cause into or add arthritis, heart periostitis,
Chronic renal is and the whole body other diseases such as a variety of illness in eye.Canker sore is a kind of common exedens damage for betiding mucous membrane of mouth
The reason for sick and wounded disease, is more common in the positions such as lip inner side, tongue, tongue abdomen, cheek mucous membrane, vestibular ditch, soft palate, it is fallen ill is many factors
Comprehensive function as a result, the wherein onset relation of the bacterium such as Streptococcus sanguis and helicobacter pylori and canker sore is close.
Eliminating bacteria, keep the most effectual way that oral hygiene is pre- anti-caries and canker sore, occurs being permitted on the market
The mouthwash of more heterogeneities, mouthwash of the prior art the component such as file containing triclosan or first nitre mostly, come strengthen its sterilization,
Fungistatic effect, but these component long-time services can cause human body necessarily to injure, thus this kind of mouthwash should not be used as it is daily
Oral care implement long-time service.
The content of the invention
The technical problem to be solved in the present invention is develop it is a kind of can pre- anti-caries and canker sore mouthwash, specific skill
Art scheme is as follows：
It is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：5-10 parts of catechin, Portugal
5-10 parts of grape polyphenol, 15-20 parts of gingerol, 8-15 parts of chamomile hydrosol, 3-8 parts of vitamin C, 4-10 parts of folic acid, sweetener 1-3
Part, 15-20 parts of Chinese medical extract, 10-20 parts of tea extract, the Chinese medical extract includes the raw material of following parts by weight：Recklessly
5-10 parts of the coptis, 5-10 parts of honeysuckle, 1-5 parts of Fructus Forsythiae, 4-8 parts of Herba Andrographitis, 5-10 parts of radix glycyrrhizae, 3-8 parts of Chinese gall, the tealeaves
Extract includes the raw material of following parts by weight：5-10 parts of green tea, 5-10 parts of oolong tea, 5-10 parts of Ilex Latifolia Thunb.
Preferably, it is described can the mouthwashes of pre- anti-caries and canker sore include the raw materials of following parts by weight：Catechin 9
Part, 6 parts of vine polyphenol, 15 parts of gingerol, 13 parts of chamomile hydrosol, 3 parts of vitamin C, 4 parts of folic acid, 1 part of sweetener, traditional Chinese medicine extraction
20 parts of thing, 20 parts of tea extract.
Preferably, the Chinese medical extract includes the raw material of following parts by weight：5 parts of Radix picrorrhizae, 8 parts of honeysuckle, Fructus Forsythiae 4
Part, 6 parts of Herba Andrographitis, 8 parts of radix glycyrrhizae, 5 parts of Chinese gall.
Preferably, the tea extract includes the raw material of following parts by weight：10 parts of green tea, 5 parts of oolong tea, Ilex Latifolia Thunb
5 parts.
Preferably, the Chinese medical extract is prepared by following methods：50 mesh are crushed to after each component is mixed, by weight
Than 1:2 addition water are uniformly mixed, and then add the saccharomycete that weight fraction is 0.5% and the cellulose that weight fraction is 0.8%
After enzyme mixing, after the 72h that ferments under conditions of 35 DEG C, the ethanol solution that the mass fraction of the weight such as addition is 30% stirs 5h,
Then filter, sterilize, filtrate removes ethanol through vacuum distillation again and obtains the Chinese medical extract.
Preferably, the tea extract is prepared by following methods：Tealeaves is added to the water, the weight ratio of tealeaves and water
For 1：3,5h is boiled, when being cooled to 35-40 DEG C, the saccharomycete that weight fraction is 0.2-0.5% is added and is uniformly mixed, Ran Hou
The ethanol solution that the mass fraction that the weight such as 72h, addition is stood under the conditions of 35-40 DEG C is 30% stirs 4h, then filters, goes out
Bacterium, filtrate remove ethanol through vacuum distillation again, that is, obtain the tea extract.
Preferably, the sweetener is Aspartame or xylitol.
Preferably, further include 0.02 part of biological preservative and 0.1 part of biological bacteriostatic agent.
Preferably, the biological preservative is made of 50wt% potassium sorbates and 50wt% sodium sorbates.
Preferably, the biological bacteriostatic agent is chitosan.
It is above-mentioned can pre- anti-caries and canker sore mouthwash preparation method, including：By catechin, vine polyphenol, ginger
Phenol, vitamin, folic acid, sweetener, biological preservative and biological bacteriostatic agent are added in deionized water and stirred evenly, raw material and water
Weight ratio is 1：3,40-50 DEG C is warming up to, stirs 3h, then sequentially adds chamomile hydrosol, Chinese medical extract, tealeaves extraction
Thing, stirs evenly, and is down to room temperature, that is, obtain it is described can pre- anti-caries and canker sore mouthwash.
The application method of mouthwash of the present invention：Sooner or later or three is postprandial, children 5-10ml, and be grown up 10-20ml, is contained in
Spue in mouthful after 30s.It need not be gargled again with clear water using after this product.It please don't be fed in half an hour, in order to avoid reducing effect.
Beneficial effects of the present invention
(1) mouthwash of the present invention is made of pure natural raw material, safe and healthy, nontoxic, can be used as daily shield
Articles for use long-time service is managed, can effectively remove intraoral bacterium, plays the effect of preferable pre- anti-caries and canker sore, and
Long-time service is to human body generation without any side effects.
(2) in mouthwash of the present invention, catechin can play preferable antibacterial, antibacterial and deodorization functions；Grape is more
Phenol has stronger anti-oxidation efficacy；Gingerol is the main active in ginger, has anti-oxidant and antibiotic effect；Chamomile is pure
Dew not only has effects that fall fire anti-inflammatory, can also play the role of fresh breath；Vitamin and folic acid can effectively prevent mouth
Chamber ulcer；Sweetener can neutralize the bitter taste of Chinese medicine, make the taste of mouthwash more preferably；Chinese medical extract, which is selected, has antibacterial anti-inflammatory
The Chinese medicine of function, can effectively kill oral bacteria, can play the role of pre- anti-caries and canker sore, and selected Chinese medicine into
Corrosion-resistant can also be played the role of by dividing；Catechin and Polyphenols are rich in tea extract, anti-oxidant and antibiotic effect can be played,
But also the taste of mouthwash can be neutralized, the delicate fragrance of tealeaves is made it have, tea extract selects green tea, oolong tea, bitter leaves
Tea is rich in catechin as raw material in green tea, is rich in Polyphenols in oolong tea after everfermentation, and Ilex Latifolia Thunb has preferable drop
Fire, antiinflammation.
Embodiment
Embodiment 1
It is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：9 parts of catechin, grape
6 parts of polyphenol, 15 parts of gingerol, 13 parts of chamomile hydrosol, 3 parts of vitamin C, 4 parts of folic acid, 1 part of sweetener, 20 parts of Chinese medical extract,
20 parts of tea extract.The Chinese medical extract includes the raw material of following parts by weight：5 parts of Radix picrorrhizae, 8 parts of honeysuckle, Fructus Forsythiae 4
Part, 6 parts of Herba Andrographitis, 8 parts of radix glycyrrhizae, 5 parts of Chinese gall.The tea extract includes the raw material of following parts by weight：10 parts of green tea, crow
Imperial 5 parts of tea, 5 parts of Ilex Latifolia Thunb.
It is above-mentioned can pre- anti-caries and canker sore mouthwash preparation method, including：By catechin, vine polyphenol, ginger
Phenol, vitamin, folic acid and sweetener are added in deionized water and stirred evenly, and the weight ratio of raw material and water is 1：3, it is warming up to 40-
50 DEG C, 3h is stirred, chamomile hydrosol, Chinese medical extract, tea extract is then sequentially added, stirs evenly, be down to room temperature, i.e.,
Obtain it is described can pre- anti-caries and canker sore mouthwash.
Embodiment 2
It is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：5 parts of catechin, grape
5 parts of polyphenol, 15 parts of gingerol, 8 parts of chamomile hydrosol, 3 parts of vitamin C, 4 parts of folic acid, 1 part of sweetener, 15 parts of Chinese medical extract, tea
10 parts of leaf extract, the Chinese medical extract includes the raw material of following parts by weight：5 parts of Radix picrorrhizae, 5 parts of honeysuckle, 1 part of Fructus Forsythiae,
4 parts of Herba Andrographitis, 5 parts of radix glycyrrhizae, 3 parts of Chinese gall, the tea extract includes the raw material of following parts by weight：5 parts of green tea, oolong tea
5 parts, 5 parts of Ilex Latifolia Thunb.
It is above-mentioned can pre- anti-caries and canker sore mouthwash preparation method, including：By catechin, vine polyphenol, ginger
Phenol, vitamin, folic acid and sweetener are added in deionized water and stirred evenly, and the weight ratio of raw material and water is 1：3, it is warming up to 40-
50 DEG C, 3h is stirred, chamomile hydrosol, Chinese medical extract, tea extract is then sequentially added, stirs evenly, be down to room temperature, i.e.,
Obtain it is described can pre- anti-caries and canker sore mouthwash.
Embodiment 3
It is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：10 parts of catechin, grape
10 parts of polyphenol, 20 parts of gingerol, 15 parts of chamomile hydrosol, 8 parts of vitamin C, 10 parts of folic acid, 3 parts of sweetener, Chinese medical extract 20
Part, 20 parts of tea extract, the Chinese medical extract includes the raw material of following parts by weight：10 parts of Radix picrorrhizae, 10 parts of honeysuckle, connect
Stick up 5 parts, 8 parts of Herba Andrographitis, 10 parts of radix glycyrrhizae, 8 parts of Chinese gall, the tea extract includes the raw material of following parts by weight：Green tea 10
Part, 10 parts of oolong tea, 10 parts of Ilex Latifolia Thunb.
The Chinese medical extract is prepared by following methods：50 mesh are crushed to after each component is mixed, by weight 1:2 add
Water is uniformly mixed, after then adding the saccharomycete that weight fraction is 0.5% and the cellulase mixing that weight fraction is 0.8%,
Fermenting under conditions of 35 DEG C after 72h, the ethanol solution that the mass fraction of the weight such as addition is 30% stirs 5h, then filter,
Sterilizing, filtrate remove ethanol through vacuum distillation again and obtain the Chinese medical extract.
Embodiment 4
It is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：6 parts of catechin, grape
9 parts of polyphenol, 18 parts of gingerol, 10 parts of chamomile hydrosol, 5 parts of vitamin C, 5 parts of folic acid, 2 parts of sweetener, 19 parts of Chinese medical extract,
15 parts of tea extract, the Chinese medical extract includes the raw material of following parts by weight：6 parts of Radix picrorrhizae, 6 parts of honeysuckle, Fructus Forsythiae 3
Part, 5 parts of Herba Andrographitis, 8 parts of radix glycyrrhizae, 7 parts of Chinese gall, the tea extract includes the raw material of following parts by weight：8 parts of green tea, crow
Imperial 6 parts of tea, 5 parts of Ilex Latifolia Thunb.
The tea extract is prepared by following methods：Tealeaves is added to the water, the weight ratio of tealeaves and water is 1：3, boil
5h is boiled, when being cooled to 35-40 DEG C, the saccharomycete that weight fraction is 0.2% is added and is uniformly mixed, then under the conditions of 35-40 DEG C
The ethanol solution that the mass fraction for standing the weight such as 72h, addition is 30% stirs 4h, then filters, sterilizes, filtrate is again through depressurizing
Ethanol is distilled off, that is, obtains the tea extract.
Embodiment 5
It is a kind of can pre- anti-caries and canker sore mouthwash, include the raw materials of following parts by weight：8 parts of catechin, grape
7 parts of polyphenol, 17 parts of gingerol, 14 parts of chamomile hydrosol, 7 parts of vitamin C, 5 parts of folic acid, 1 part of Aspartame, Chinese medical extract 16
Part, 10 parts of tea extract, 0.02 part of biological preservative and 0.1 part of biological bacteriostatic agent, the biological preservative is by 50wt% mountains
Potassium sorbate and 50wt% sodium sorbates composition, the biological bacteriostatic agent is chitosan.
The Chinese medical extract includes the raw material of following parts by weight：9 parts of Radix picrorrhizae, 8 parts of honeysuckle, 4 parts of Fructus Forsythiae, Herba Andrographitis
7 parts, 9 parts of radix glycyrrhizae, 7 parts of Chinese gall, the tea extract includes the raw material of following parts by weight：9 parts of green tea, 9 parts of oolong tea, hardship
6 parts of fourth tea.
The Chinese medical extract is prepared by following methods：50 mesh are crushed to after each component is mixed, by weight 1:2 add
Water is uniformly mixed, after then adding the saccharomycete that weight fraction is 0.5% and the cellulase mixing that weight fraction is 0.8%,
Fermenting under conditions of 35 DEG C after 72h, the ethanol solution that the mass fraction of the weight such as addition is 30% stirs 5h, then filter,
Sterilizing, filtrate remove ethanol through vacuum distillation again and obtain the Chinese medical extract.
Preferably, the tea extract is prepared by following methods：Tealeaves is added to the water, the weight ratio of tealeaves and water
For 1：3,5h is boiled, when being cooled to 35-40 DEG C, the saccharomycete that weight fraction is 0.5% is added and is uniformly mixed, then in 35-40
The ethanol solution that the mass fraction that the weight such as 72h, addition is stood under the conditions of DEG C is 30% stirs 4h, then filters, sterilizes, filtrate
Ethanol is removed through vacuum distillation again, that is, obtains the tea extract.
It is above-mentioned can pre- anti-caries and canker sore mouthwash preparation method, including：By catechin, vine polyphenol, ginger
Phenol, vitamin, folic acid, sweetener, biological preservative and biological bacteriostatic agent are added in deionized water and stirred evenly, raw material and water
Weight ratio is 1：3,40-50 DEG C is warming up to, stirs 3h, then sequentially adds chamomile hydrosol, Chinese medical extract, tealeaves extraction
Thing, stirs evenly, and is down to room temperature, that is, obtain it is described can pre- anti-caries and canker sore mouthwash.
Experimental example
To verify the effect of mouthwash of the present invention, following experiment is carried out to mouthwash obtained by embodiment 1-5 and is said
It is bright.
Subjects：Experimental group mouthwash obtained by embodiment 1-5, control group is the physiology salt that mass fraction is 0.9%
Water.
1. antibacterial experiment
Test bacterium：Candida albicans, Streptococcus sanguis, streptococcus mutans, actinomyces viscosus, golden yellow staphylococcus, large intestine
Bacillus.
Test method：With reference to GB15979-2002 appendix Cs 3 carry out antibacterial tests, bacteriostasis rate=(control group survival bacterium number-
Experimental group survival bacterium number)/control group survival bacterium number.
Result of the test is as shown in table 1.
The bacteriostasis rate of mouthwash obtained by 1. embodiment 1-5 of table
Result of the test shows mouthwash of the present invention to Candida albicans, Streptococcus sanguis, streptococcus mutans, Actinomyces
Bacterium, golden yellow staphylococcus and Escherichia coli have preferable fungistatic effect.
2. anti-inflammatory is tested
Test method：120 mouse are taken, 6 groups is randomly divided into, every group 20, the left ear of mouse is applied to 20ul dimethylbenzene,
Mouthwash obtained by 1ml embodiments 1-5 is uniformly smeared in left ear inflamed sites after 1h, 30min once, continuous 3 times, do not appoint by auris dextra
Where is managed, and is put to death mouse after 3h, is taken the auricle of same area to weigh, and calculates swelling rate.Swelling rate=(left auricle weight-auris dextra piece
Weight)/auris dextra piece weight, it is averaged, the results are shown in Table 2.
The anti-inflammatory effects of mouthwash obtained by 2. embodiment 1-5 of table
Mouthwash of the present invention has preferable antiinflammation as can be seen from the table.
Claims (10)
1. it is a kind of can pre- anti-caries and canker sore mouthwash, it is characterised in that include the raw material of following parts by weight：Catechin
5-10 parts, 5-10 parts of vine polyphenol, 15-20 parts of gingerol, 8-15 parts of chamomile hydrosol, 3-8 parts of vitamin C, 4-10 parts of folic acid, sweet tea
1-3 parts of taste agent, 15-20 parts of Chinese medical extract, 10-20 parts of tea extract, the Chinese medical extract include following parts by weight
Raw material：5-10 parts of Radix picrorrhizae, 5-10 parts of honeysuckle, 1-5 parts of Fructus Forsythiae, 4-8 parts of Herba Andrographitis, 5-10 parts of radix glycyrrhizae, 3-8 parts of Chinese gall,
The tea extract includes the raw material of following parts by weight：5-10 parts of green tea, 5-10 parts of oolong tea, 5-10 parts of Ilex Latifolia Thunb.
2. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that including following parts by weight
Raw material：9 parts of catechin, 6 parts of vine polyphenol, 15 parts of gingerol, 13 parts of chamomile hydrosol, 3 parts of vitamin C, 4 parts of folic acid, sweet taste
1 part of agent, 20 parts of Chinese medical extract, 20 parts of tea extract.
3. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that the Chinese medical extract
Include the raw material of following parts by weight：5 parts of Radix picrorrhizae, 8 parts of honeysuckle, 4 parts of Fructus Forsythiae, 6 parts of Herba Andrographitis, 8 parts of radix glycyrrhizae, 5 parts of Chinese gall.
4. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that the tea extract
Include the raw material of following parts by weight：10 parts of green tea, 5 parts of oolong tea, 5 parts of Ilex Latifolia Thunb.
5. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that the Chinese medical extract
Prepared by following methods：50 mesh are crushed to after each component is mixed, by weight 1:2 addition water are uniformly mixed, and then add weight
After measuring the saccharomycete that fraction is 0.5% and the cellulase mixing that weight fraction is 0.8%, after the 72h that ferments under conditions of 35 DEG C,
The ethanol solution that the mass fraction of the weight such as addition is 30% stirs 5h, then filters, sterilizes, filtrate removes through being evaporated under reduced pressure again
Ethanol obtains the Chinese medical extract.
6. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that the tea extract
Prepared by following methods：Tealeaves is added to the water, the weight ratio of tealeaves and water is 1：3,5h is boiled, when being cooled to 35-40 DEG C, is added
Enter the saccharomycete that weight fraction is 0.2-0.5% to be uniformly mixed, the weight such as 72h, addition is then stood under the conditions of 35-40 DEG C
The ethanol solution that mass fraction is 30% stirs 4h, then filters, sterilizes, filtrate removes ethanol through vacuum distillation again, that is, obtains institute
State tea extract.
7. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that：The sweetener for Ah
This Ba Tian or xylitol.
8. according to claim 1 can pre- anti-caries and canker sore mouthwash, it is characterised in that：Further include 0.02 part of life
Thing preservative and 0.1 part of biological bacteriostatic agent.
9. according to claim 8 can pre- anti-caries and canker sore mouthwash, it is characterised in that：The biological preservative
It is made of 50wt% potassium sorbates and 50wt% sodium sorbates, the biological bacteriostatic agent is chitosan.
10. as described in claim 1-9 is any can pre- anti-caries and canker sore mouthwash preparation method, its feature exists
In, including：Catechin, vine polyphenol, gingerol, vitamin, folic acid, sweetener, biological preservative and biological bacteriostatic agent are added
Stirred evenly in deionized water, the weight ratio of raw material and water is 1：3,40-50 DEG C is warming up to, 3h is stirred, then sequentially adds ocean
Camomile hydrosol, Chinese medical extract, tea extract, stir evenly, and are down to room temperature, that is, obtain it is described can pre- anti-caries and oral cavity burst
The mouthwash of ulcer.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114642616A (en) * | 2022-01-17 | 2022-06-21 | 西南大学 | Mouth wash based on mulberry leaf polyphenol and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4188326B2 (en) * | 2005-02-10 | 2008-11-26 | アース製薬株式会社 | Liquid oral composition |
| CN103315938A (en) * | 2013-07-12 | 2013-09-25 | 孙佳丽 | Anti-oxidative mouthwash |
| JP5750675B2 (en) * | 2011-02-18 | 2015-07-22 | ユースキン製薬株式会社 | Oral composition |
| CN105395467A (en) * | 2015-12-01 | 2016-03-16 | 山东皓尔生物工程有限公司 | Traditional Chinese medicinal composition, skin-care cosmetic and application of skin-care cosmetic |
| CN106491725A (en) * | 2016-12-30 | 2017-03-15 | 郑州掌盟网络科技有限公司 | A kind of treat pharmaceutical composition of oral ulcer and preparation method thereof |
| CN107184476A (en) * | 2017-06-16 | 2017-09-22 | 河北康正药业有限公司 | A kind of antibacterial mouthwash and preparation method thereof |
| CN107296763A (en) * | 2017-09-11 | 2017-10-27 | 佛山市聚成生化技术研发有限公司 | A kind of mouthwash containing gingerol |
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2017
- 2017-12-21 CN CN201711396145.8A patent/CN107898705B/en active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4188326B2 (en) * | 2005-02-10 | 2008-11-26 | アース製薬株式会社 | Liquid oral composition |
| JP5750675B2 (en) * | 2011-02-18 | 2015-07-22 | ユースキン製薬株式会社 | Oral composition |
| CN103315938A (en) * | 2013-07-12 | 2013-09-25 | 孙佳丽 | Anti-oxidative mouthwash |
| CN105395467A (en) * | 2015-12-01 | 2016-03-16 | 山东皓尔生物工程有限公司 | Traditional Chinese medicinal composition, skin-care cosmetic and application of skin-care cosmetic |
| CN106491725A (en) * | 2016-12-30 | 2017-03-15 | 郑州掌盟网络科技有限公司 | A kind of treat pharmaceutical composition of oral ulcer and preparation method thereof |
| CN107184476A (en) * | 2017-06-16 | 2017-09-22 | 河北康正药业有限公司 | A kind of antibacterial mouthwash and preparation method thereof |
| CN107296763A (en) * | 2017-09-11 | 2017-10-27 | 佛山市聚成生化技术研发有限公司 | A kind of mouthwash containing gingerol |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114642616A (en) * | 2022-01-17 | 2022-06-21 | 西南大学 | Mouth wash based on mulberry leaf polyphenol and preparation method thereof |
| CN114642616B (en) * | 2022-01-17 | 2024-01-26 | 西南大学 | Mulberry leaf polyphenol-based mouthwash and preparation method thereof |
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| Publication number | Publication date |
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| CN107898705B (en) | 2021-01-12 |
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