CN107898666A - A kind of restoring consciouness of high-content geraniol plants essential oil synergy, anticreep hair-care shampoo - Google Patents
A kind of restoring consciouness of high-content geraniol plants essential oil synergy, anticreep hair-care shampoo Download PDFInfo
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- CN107898666A CN107898666A CN201710941127.7A CN201710941127A CN107898666A CN 107898666 A CN107898666 A CN 107898666A CN 201710941127 A CN201710941127 A CN 201710941127A CN 107898666 A CN107898666 A CN 107898666A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The present invention relates to a kind of restoring consciouness of plants essential oil synergy, Anti-hair loss shampoo composite.The shampoo composite of the present invention is in addition to shampoo formula usual component, also comprising following component：Account for 0.25 0.5% caffeine of shampoo composite percentage by weight；Account for the plant essential oil composition of 0.5 3.0% high-content geraniol of shampoo composite percentage by weight.Wherein high-content geraniol plant essential oil composition can effectively facilitate the Transdermal absorption of caffeine, refreshed the mind with synergy, improve Scalp hair follicles active function, long-time service can prevent or reduce alopecia.
Description
Technical field
The invention belongs to daily chemical product field, the plants essential oil synergy caffeine for being related to a kind of high-content geraniol is waken up
Brain, anticreep scalp care shampoo.
Background technology
Hair follicle is the important accessory organ of scalp, is made of polytype cell.The periodically growth of hair follicle experience
(anagen), degenerate (catagen) and the continuous of static (telogen) three phases repeats.Undergoing the growth in one period
Hair follicle enters catagen afterwards, and hair Hair bulb cell starts apoptosis at this time, and hair follicle experiences outer signals stimulation, at secondary hair bud
Hair papilla cell start to breed at first, trigger the hair follicle development of a new round.Hair follicle cycle often leads to serious hair follicle extremely
Disease, such as alopecia areata, androgenetic alopecia, alopecia senilis and postpartum alopecia etc..Cell culture experiments in vitro confirms a certain concentration
The caffeine of scope has facilitation to hair follicle cell cycle regulating, particularly hair papilla cell propagation.Therefore, caffeine can be made
For scalp care, hair follicle regresses are prevented, safeguard the active ingredient of hair healthy growth.
Low dose of purine alkaloid class compound caffeine (CAFFEINE), theophylline (THEOPHYLLINE) can be with intracerebrals
Potent hypnosis material adenosine receptor A2AWith reference to, produce the rush awakening opposite with adenosine and act on, that is, the effect to refresh the mind.It is existing
There is research to confirm that coffee has the curative effect of medication for weakening neurogenic pain；Exercise tolerance can be also improved, there is resisting kinetic
Fatigue effect.These researchs are established on the basis of caffeine is effectively passed to central nervous system target spot by oral administration.Caffeine
Reaching central nervous system with enteron aisle Passive diffusion by oral administration at least needs 5min, and reaching top at least needs 30min.But swim
Caffeine from form differs greatly in the penetration of epidermis compared with intestinal mucosa absorption.And elute what is contacted in class product with scalp
Time is shorter, and usual action time is no more than 3min.And make the capillary and biography of quick, the effective arrival skin corium of caffeine
The problem of being delivered to central nervous system target spot, being there is presently no researching and solving.Present invention discover that the geraniol in plants essential oil
13-16 times of caffeine transdermal absorption factor can be improved as effective penetrating agent of caffeine, and with the plant of high-content geraniol
Essential oil collaboration plays the pleasure of Central nervous system, the effect rouse oneself.
The content of the invention
A kind of restoring consciouness of high-content geraniol plants essential oil synergy, Anti-hair loss scalp care shampoo composite, except shampoo is matched somebody with somebody
Outside square usual component, also comprising following component：Account for shampoo composite percentage by weight 0.25-0.5% caffeines；Account for shampoo compositions
The folk prescription plants essential oil or compound plant essential oil of thing percentage by weight 0.5-3.0% high-content geraniols.
The spiceleaf alcohol content of folk prescription plants essential oil of the present invention accounts for the plants essential oil percentage by weight more than 10%.
The folk prescription plants essential oil of high-content geraniol of the present invention is oil of Cymbopogon winterianus, Rosa Damascana, rose flower essential oil, mountain
Any one of pepper essential oil.
The spiceleaf alcohol content of compound plant essential oil of the present invention accounts for shampoo composite percentage by weight more than 0.3%.
The detailed description of invention
Restoring consciouness of the present invention, Anti-hair loss scalp care shampoo composite, most important mechanism be caffeine with
The combination synergy of high-content geraniol plants essential oil, concentration range (percentage by weight) choosing of the caffeine in shampoo composite
Select.
Hair follicle is the important accessory organ of skin, is made of polytype cell.The periodically growth of hair follicle experience
(anagen), degenerate (catagen) and the continuous of static (telogen) three phases repeats.Undergoing the growth in one period
Hair follicle enters catagen afterwards, and hair Hair bulb cell starts apoptosis at this time, and hair follicle experiences outer signals stimulation, at secondary hair bud
Hair papilla cell start to breed at first, trigger the hair follicle development of a new round.Hair follicle cycle often leads to serious hair follicle extremely
Disease, such as alopecia areata, androgenetic alopecia, alopecia senilis and postpartum alopecia etc..Cell culture experiments in vitro confirms a certain concentration
The caffeine of scope has facilitation to hair follicle cell cycle regulating, particularly hair papilla cell propagation.Therefore, caffeine can be made
For scalp care, hair follicle regresses are prevented, safeguard the active ingredient of hair healthy growth.
Hair papilla cell is the corium source property cell positioned at hair follicle basal part, and the important function of hair papilla cell is induction hair
Capsule regenerates.(caffeine is to vitro culture of human by the experiment of hair papilla cell in vitro culture for No.1 Attached Hospital, Nanjing Medical Univ
The influence of hair follicle and hair papilla cell, clinic skin section magazine 2011,40 (6)：323-327) prove that caffeine concentration is less than
When 0.0025%, there is a facilitation to hair papilla cell propagation, facilitation is most notable when especially 0.0005%, and RT-PCR
Detection shows at the same time to promote the expression of relevant cell growth factor ER, VEGF, FGF to increase；And caffeine concentration is more than
0.0125% (w/w) is then obviously promoted hair papilla cell apoptosis, and reduces relevant cell factor expression.And for shampoo composite
For usually require 10-20 times of water come dilute use, calculate and absorbed then by added caffeine 100%, add caffeine
The upper limit is 0.25%, and it is effective activation hair follicle that lower limit, which is calculated as 0.0005%*10=0.05%, and hair papilla cell is increased
Grow the suitable concentration of no inhibitory action.
According to coffee for drinking because of pharmacokinetics (pharmacological action and application of caffeine, 2005,18 (3), 270-275) point
Analysis, adult drink low dosage 100-250mg caffeines, and can reach the micro- g kgs of 8-10 in peak plasma concentration can ensure
In central nervous system (1：1) play the role of in bracing.Namely drunk if if Transdermal absorption efficiency can reach
Absorption efficiency；Shampoo usage amount then needs shampoo caffeine concentration to reach 1.0%-5.0% (w/w) according to 5-10g/ times.Can
See it has to be ensured that caffeine is transdermal more efficient, the excitation of both Central nervous systems is just can guarantee that, without to hair follicle
Growth produces suppression.Present invention discover that the plants essential oil rich in geraniol can significantly improve caffeine absorption efficiency, in this hair
Under bright formula system and plants essential oil geraniol concentration conditions, account for formula system percentage by weight 0.25%-0.5%'s (w/w)
Caffeine additive amount can both reach the immediate effect to refresh the mind, and long-time service, which can also reach, improves hair follicle growth rate, prevents
Control the symptom of alopecia/hair loss；Statistical result on probation is also without there is a phenomenon where suppress hair follicle growth.
The folk prescription plants essential oil of high-content geraniol of the present invention is oil of Cymbopogon winterianus, Rosa Damascana, rose flower essential oil, mountain
Any one of pepper essential oil.
Geraniol, English name Lemonol；Alias, geraniol, Geraniol, 2,6-Octadien-1-ol, 3,7-
dimethyl-(E)；Molecular formula；C10H18O.Various plants essential oil contains geraniol.
Oil of Cymbopogon winterianus derives from the volatile oil of lemongrass Cymbopogon citrantus.Lemongrass is planted for perennial grass family
Thing, alias lemon grass (Cymbopogon citratus), ginger grass, strong wind thatch, plantation is in global torrid areas extensively.Oil of Cymbopogon winterianus main component is citronellal
And geraniol, differed according to specific kind, the content of place of production difference geraniol in 19%-25% (w/w).
Rosa Damascana is known as the title of liquid golden, and producing the rose variety of essential oil has perfume rose, main perfume rose
It is divided into three big sources：The Rosa gallica in Caucasia is originated in, the Provence rose in Persian is originated in and originates in Syria
Damask Rose, in addition also two unique branches are bitter water rose and the polyphyll rose of China.Different cultivars, producing region and
The main aromatic components of the Rosa Damascana of extraction process are citronellol, geraniol, nerol, linalool；Geraniol ratio is usual
At 6%-22% (w/w).
Its main chemical compositions of the Chemical Composition of The Essential Oil of rose are benzyl carbinol, vanillyl alcohol, geraniol, linalool, cloves
Phenol, methyl eugenol, nerol, C- rose oxides etc..
The main chemical compositions difference of greyblue spicebush leaf essential oil oil can be divided into two types:I, is mainly containing geraniol, vanillyl alcohol
Mainly contain ocimenum, laurene, beta-elemene and other chemical compositions with II, of eucalyptol.
Advantageous effect of the invention
Present invention discover that the geraniol in plants essential oil can significantly improve caffeine as effective penetrating agent of caffeine
Transdermal absorption factor (13-16 times), and with the plants essential oil of high-content geraniol can cooperate with play Central nervous system pleasure,
The restoring consciouness effect rouse oneself.
The shampoo of concentration range caffeine of the present invention is activated and grown to hair follicle cell, and particularly hair papilla cell increases
The effect of remarkably promoting is grown, long-time service can effectively nurse scalp, delaying senility, and reduce alopecia hair loss.
The meaning of plant essential oil composition synergy caffeine, which is not only in that, can obtain instant lifting restoring consciouness effect, and
Even if due to different plant essential oil compositions since spiceleaf alcohol content is high, head perfume (or spice) is similar, but total body note atmosphere effect is different, is adapted to not
The other crowd of the same sex.
Here is the non-limiting example of the detergent composition of the present invention.These embodiments are only given to say
Bright purpose, can not be interpreted as limitation of the invention, because without departing from the spirit and scope of the present invention, can
To carry out many changes to the present invention.In these embodiments, unless stated otherwise, all concentration is all percentage by weight.
Embodiment
1. caffeine and plant essential oil composition embodiment
Shampoo formula of the present invention includes conventional shampoo components, including the group added below according to percentage by weight
Point：Anion surfactant 10-25%, amphoteric surfactant/nonionic surfactant 2-10%, cation opsonizing agent
1.0-5.0%, silicone emulsion 0-3.0%, plant base oil 0-10%, pearling agent 0-2.0%, thickener 0.3-5.0%, anti-corrosion
Appropriate agent；Using no silicone oil formula system, protosulfate or better without sulfate formula system.
2. sensory evaluation
The sensory evaluation method is：By 8 embodiments and and without the IV (plants essential oil of negative control for adding caffeine
3.0%w/w, oil of Cymbopogon winterianus, Rosa Damascana, each 1.0%w/w of rose plants essential oil) and without essential oil composition addition Ⅹ (coffee
Because of 0.375%w/w), 30 testers are issued at random contrasts use.According to identical when tester uses hair washing water sample
Method is washed hair, and every kind of shampoo respectively uses 90 days.Alopecia effect is reduced according to daily hair loss quantity survey (surveying).Standards of grading use 10
Divide system, for 1-2 entirely without effect, 3-4 divides effect unobvious, and 5-6 points effective, and 7-8 divides significant effect, and 9-10 divides effect very aobvious
Write.Various shampoo composite using effect evaluation results are listed in table 1.
1 shampoo composite restoring consciouness anticreep sensory evaluation of table
Claims (4)
1. a kind of restoring consciouness of high-content geraniol plants essential oil synergy, Anti-hair loss shampoo composite, except shampoo formula usual component
Outside, also comprising following component：Account for shampoo composite percentage by weight 0.25-0.5% caffeines；Account for shampoo composite weight percent
Than the folk prescription plants essential oil or compound plant essential oil of 0.5-3.0% high-content geraniols.
2. shampoo composite according to claim 1, it is characterised in that the spiceleaf alcohol content of the folk prescription plants essential oil accounts for
The plants essential oil percentage by weight more than 10%.
3. shampoo composite according to claim 2, it is characterised in that the folk prescription plants essential oil of the high-content geraniol
For any one of oil of Cymbopogon winterianus, Rosa Damascana, rose flower essential oil, lindera glauca essential oil.
4. shampoo composite according to claim 1, it is characterised in that the spiceleaf alcohol content of the compound plant essential oil accounts for
Shampoo composite percentage by weight more than 0.3%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710941127.7A CN107898666A (en) | 2017-10-11 | 2017-10-11 | A kind of restoring consciouness of high-content geraniol plants essential oil synergy, anticreep hair-care shampoo |
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| CN201710941127.7A CN107898666A (en) | 2017-10-11 | 2017-10-11 | A kind of restoring consciouness of high-content geraniol plants essential oil synergy, anticreep hair-care shampoo |
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| CN107898666A true CN107898666A (en) | 2018-04-13 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108904434A (en) * | 2018-08-18 | 2018-11-30 | 安徽国科生物科技有限公司 | A kind of stem cell hair growth stimulating shampoo and preparation method thereof |
| CN110859764A (en) * | 2019-10-31 | 2020-03-06 | 拉芳家化股份有限公司 | Scalp sunscreen composition |
| CN115606797A (en) * | 2021-07-12 | 2023-01-17 | 芙蓝宝株式会社 | Composition for promoting hair growth or inhibiting alopecia comprising water-soluble mastic gum and fructus Piperis extract |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397229A (en) * | 2011-11-19 | 2012-04-04 | 大连得达科技发展有限公司 | Refreshing and brain invigorating liquid shampoo |
| CN102697674A (en) * | 2012-06-26 | 2012-10-03 | 欧美龙（南通）重防腐涂料有限公司 | Liquid shampoo for babies |
| CN104147186A (en) * | 2014-07-19 | 2014-11-19 | 云南荣之健生物科技有限公司 | Rose essential oil hydrogel plaster and preparation method thereof |
| CN104257596A (en) * | 2014-09-16 | 2015-01-07 | 拉芳家化股份有限公司 | Mild oil-control shampoo with cool feeling |
| CN105581917A (en) * | 2016-02-23 | 2016-05-18 | 广州市高姿化妆品有限公司 | Cosmetic composition for enhancing tensile strength and extensibility of keratin fiber, and especially hair |
| CN105708754A (en) * | 2016-01-30 | 2016-06-29 | 佛山市南海清秀化妆品有限公司 | Hair-follicle-cleaning and hair-nourishing emulsion and preparing method thereof |
| CN105997596A (en) * | 2016-07-08 | 2016-10-12 | 拉芳家化股份有限公司 | Dandruff removing composition containing plant essential oil having synergistic effect and application thereof |
-
2017
- 2017-10-11 CN CN201710941127.7A patent/CN107898666A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397229A (en) * | 2011-11-19 | 2012-04-04 | 大连得达科技发展有限公司 | Refreshing and brain invigorating liquid shampoo |
| CN102697674A (en) * | 2012-06-26 | 2012-10-03 | 欧美龙（南通）重防腐涂料有限公司 | Liquid shampoo for babies |
| CN104147186A (en) * | 2014-07-19 | 2014-11-19 | 云南荣之健生物科技有限公司 | Rose essential oil hydrogel plaster and preparation method thereof |
| CN104257596A (en) * | 2014-09-16 | 2015-01-07 | 拉芳家化股份有限公司 | Mild oil-control shampoo with cool feeling |
| CN105708754A (en) * | 2016-01-30 | 2016-06-29 | 佛山市南海清秀化妆品有限公司 | Hair-follicle-cleaning and hair-nourishing emulsion and preparing method thereof |
| CN105581917A (en) * | 2016-02-23 | 2016-05-18 | 广州市高姿化妆品有限公司 | Cosmetic composition for enhancing tensile strength and extensibility of keratin fiber, and especially hair |
| CN105997596A (en) * | 2016-07-08 | 2016-10-12 | 拉芳家化股份有限公司 | Dandruff removing composition containing plant essential oil having synergistic effect and application thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108904434A (en) * | 2018-08-18 | 2018-11-30 | 安徽国科生物科技有限公司 | A kind of stem cell hair growth stimulating shampoo and preparation method thereof |
| CN110859764A (en) * | 2019-10-31 | 2020-03-06 | 拉芳家化股份有限公司 | Scalp sunscreen composition |
| CN115606797A (en) * | 2021-07-12 | 2023-01-17 | 芙蓝宝株式会社 | Composition for promoting hair growth or inhibiting alopecia comprising water-soluble mastic gum and fructus Piperis extract |
| WO2023286919A1 (en) * | 2021-07-12 | 2023-01-19 | 주식회사 프롬바이오 | Composition for promoting hair growth or inhibiting hair loss using solubilized mastic gum and lindera glauca blume extract |
| CN115606797B (en) * | 2021-07-12 | 2024-05-03 | 芙蓝宝株式会社 | Composition for promoting hair growth or inhibiting hair loss by using water-soluble emulsion gum and fructus Piperis extract |
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