CN107897615A - A kind of Xuancheng's pawpaw solid beverage for being used to improve constipation - Google Patents

A kind of Xuancheng's pawpaw solid beverage for being used to improve constipation Download PDF

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CN107897615A
CN107897615A CN201711154306.2A CN201711154306A CN107897615A CN 107897615 A CN107897615 A CN 107897615A CN 201711154306 A CN201711154306 A CN 201711154306A CN 107897615 A CN107897615 A CN 107897615A
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parts
xuancheng
pawpaw
solid beverage
constipation
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陈家胜
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XUANCHENG HUAKE XUANMUGUA BIOTECHNOLOGY CO., LTD.
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Ningguo Balanced Health Management Co Ltd
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    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
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    • A61K36/88Liliopsida (monocotyledons)
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract

The present invention provides a kind of Xuancheng's pawpaw solid beverage for being used to improve constipation, it is prepared by the raw material of following parts by weight:20 30 parts of Xuancheng's pawpaw, 10 20 parts of witloof, 15 25 parts of bitter orange flower, 8 12 parts of hoveniae semoveniae semen, 8 12 parts of sealwort, 10 20 parts of Leaves of Hippophae L, 10 18 parts of purple perilla seed, 5 10 parts of peach kernel, and employ corresponding preparation method, solid beverage is prepared into, function of the invention improves constipation.

Description

A kind of Xuancheng's pawpaw solid beverage for being used to improve constipation
Technical field
The present invention relates to health product technology field, and in particular to a kind of Xuancheng's pawpaw solid beverage and system for being used to improve constipation Preparation Method and application.
Background technology
Constipation refer to due to large intestine conduction function it is not normal caused by it is difficult with stool discharge, when defecation time or infrequent defecation Between be extended for a kind of large intestine disease of Clinical symptoms.Constipation is both a kind of independent disease, and one in a variety of acute and chronic diseases The symptom often occurred during disease, this section only discuss the former.Traditional Chinese medicine has this disease abundant Couple herbs and good The effect of.《Interior warp》In have realized that constipation is caught cold with taste, have in intestines heat it is related with nephrosis, such as《Plain Questions is fainted by a piece》 Say:" lunar faints, then it is swollen to expire kneecap for abdomen, rear unfavorable.”《Plain Questions lifts pain and discusses a piece》Say:" hot gas is stayed in small intestine, pain in the intestine, illness heat Terribly thirsty, then hard do does not draw, therefore abdominal pain with constipation is obstructed.”《Ling Shu Miraculous Pivot or Divine Axis perverse trend cacosplanchnia shape》Say:" kidney weak pulse is anxious, before must not be Afterwards." Zhong Jing there has been constipation more comprehensive understanding, it is proposed that cold, hot, empty, real different pathogenesis, set up CHENGQI TANG Bitter cold rush down under, the yin-nourishing mild laxation of Maziren Wan, is later age doctor under the qi-regulating of three thing soup of Cortex Magnoliae Officinalis is led to, and all methods of honey suppository Recognize and treat this disease and establish basic principle, some prescriptions are still common by clinical treatment constipation so far.Li Dong Yuan is emphasized to drink The relation of work and rest and constipation is eaten, and points out that treatment constipation can not abuse cathartic, such as《Secret record of the orchid chamber stool ties dry door》Meaning:If " Famine is full to forfeit one's integrity, and forced labour is excessive, damages stomach Qi, and the thing of the hot savoury of food, and helps fire-evil, lies prostrate in blood, dissipates Kidney-Yin, body fluid loses It is few, therefore dry feces." " on the whole cure the disease, can not without exception with crotons, lead a cow etc it is lower it, damage its body fluid, constipation is more, multiple lower multiple Knot, pole is then so that be guided in down and obstructed, then into not rescuing." Cheng Zhongling《Medicine Comprehended constipation》Constipation is divided into " real Four types of secret, empty secret, hot secret, constipation due to endogenous cold ", and all kinds of symptoms, therapy and prescription are listed respectively, there is certain reference to clinic Value.
Functional consitipation in western medicine, that is, belong to this disease category, irritable bowel syndrome, enteritis convalescence, rectum and anus Constipation caused by disease, drug induced constipation, the constipation caused by the constipation caused by endocrine and metabolic disease, and muscular strength decline Deng can refer to this section diagnosis and treatment.
The cause of disease of constipation is many, wherein the main heresy for having diseases caused by external factors fever and chills, internal injury diet feelings will is physically weak after being ill, Yang blood and qi deficiency etc..This disease disease position is and closely related with taste lung liver kidney in large intestine.Insufficiency of the spleen transmission is powerless, stops in waste matter, causes Large intestine conduction function is not normal, into constipation;Stomach is connected with intestines, stomach excessive heat, passes large intestine down, burns bright body fluid, large intestine excess heat, dry dung Interior knot, can be into constipation;The lung and the large intestine being interior-exteriorly related, the scorching of lung move down large intestine, then large intestine conduction function is not normal, into constipation;Liver Main catharsis mechanism of qi, if irritability stasis, the stagnation of the circulation of vital energy is not all right, and internal organs gas cannot be unimpeded;Five liquid of kidney master and take charge of two just, if the deficiency of the kidney yin, Enteron aisle loses profit, and large intestine is lost in warm and transmit powerless, constipation if the insufficiency of the kidney yang, can cause constipation.Its etiology and pathogenesis It is summed up, can substantially divides following aspects:
1. stomach accumulated heat innate excess of YANG in the body, or after pyreticosis, waste heat is reluctant to leave, or the lung heat dryness of the lung, move down large intestine, or overfeeding pure wine Savoury, or overfeeding are pungent, or cross and take the medicine of a warm nature, can cause stomach accumulated heat, and consumption hinders body fluid, and enteron aisle is dry and astringent to lose profit, the drying of excrement matter, it is difficult to Discharge, forms so-called " heat is secret ".Such as《Jing Yue's complete work is constipated》Say:" yang constipation is demonstrate,proved, and must be had a surplus because of pathogenic fire, be dried with bringing about the spread of body fluid.”
2. depression and stagnation of QI sorrow is pondered over, spleen is felt frustrated knot;Or depressed angry, stagnation of QI due to depression of the liver;Or sitting is moved less, disorder of qi, Can cause the internal organs obstruction of the circulation of vital energy stagnant, lead to that drop is not normal, and conduction dereliction of duty, stops in waste matter, must not downlink, or be intended to just not go out, or go out without smooth, or Dry and hard excrement is secret into gas.Such as《The deficient wing constipation of gold》Say:" the secret person of gas, it is stagnant in gas and thing is not all right.”
The addiction to uncooked and cold food 3. cold sensation of the genitalia stagnates, stagnate stomach and intestine;Or diseases caused by external factors cold-evil, straight middle stomach;Or cross and take cold and cool, knot in cold sensation of the genitalia, Can cause it is yin-cold excess, stagnate stomach and intestine, conduction it is not normal, waste matter is not all right, into constipation due to endogenous cold.Such as《The deficient wing constipation of gold》Day:" constipation due to endogenous cold Person, the gas of cold, lies across stomach, coagulates cloudy consolidation, yang-energy is not all right, and body fluid is obstructed.”
The improper diet and overtiredness 4. deficiency of vital energy sun declines, taste are damaged;Or ferritic is weak, YANG QI deficiency;Or it is old and frail, deficiency of vital energy sun declines; Or prolonged illness postpartum, healthy tendency is not multiple;Or eating cold and uncooked food excessively, damage yang-energy;Or bitter cold is sent an expedition against, impairment of yang gas consumption, can cause deficiency of vital energy sun to decline, Then large intestine conduction is powerless for the deficiency of vital energy, and then enteron aisle loses in warm the deficiency of yang, knot in cold sensation of the genitalia, just under it is powerless, extend defecation time, formed just It is secret.Such as《Jing Yue's complete work, it is constipated》Say:" all lower burnt deficiency of yang, then yang-energy is not all right, and yang-energy is not all right, cannot transmit, and the moon is coagulated under, This deficiency of yang and yin constipation.”
5. the deficiency of yin-fluid and blood ferritic deficiency of Yin;Body fluid deficiency blood is few;Or postpartum, the cloudy deficiency of blood are few after being ill;Or lose blood and take sweat by force, hinder Tianjin hemorrhage bleeding; Or year height it is weak, deficiency of YIN-blood;Or the pungent perfume of overfeeding is scorching, cloudy blood being lost, can cause deficiency of yin-fluid and blood, then large intestine is not flourish for the deficiency of blood, Then large intestine is dry and astringent for yin deficiency, and enteron aisle loses profit, and dry and hard excrement is just lower difficult, into constipation.Such as《Required Readings for Medical Professionals constipation》Say: " more there is old body fluid to dry up, married woman's postpartum hemorrhage bleeding, and sweating diuresis, vim and vigour are not multiple after being ill, all can be constipated.”
Between above-mentioned various etiology and pathogenesis usually mutually and be disease, or mutual inversion of phases, as stomach accumulated heat and depression and stagnation of QI can be with And see, cold sensation of the genitalia stagnates can be mutually simultaneous with deficient and weak YANG QI;With the passing of time depression and stagnation of QI changes heat, can cause thermojunction;With the passing of time thermojunction, consumes impairment of yin Tianjin, and deficiency of Yin etc. can be changed into.However, constipation, always using actual situation as guiding principle, constipation due to endogenous cold, heat is secret, gas is secret true, yang blood and qi deficiency institute The empty secret then category of cause is empty.Can be converted between actual situation, can deficiency syndrome developing to excess syndrome, can sthenia symptoms caused by asthenia, and actual situation and see.It is summed up, shape Basic pathogenesis into constipation is evil stagnant large intestine, and internal organs is gas-tight plug is obstructed or intestines lose gentle, promotes powerless, causes large intestine conduction function to lose Often.
The content of the invention
Goal of the invention:To solve the above-mentioned problems, the present inventor has found that the present invention has good improve just in clinical research Secret effect, thus it is an object of the invention to provide it is a kind of be used for improve constipation Xuancheng's pawpaw solid beverage and preparation method and Using.
Technical solution:A kind of Xuancheng's pawpaw solid beverage for being used to improve constipation, it is prepared by the raw material of following parts by weight Obtain:20-30 parts of Xuancheng's pawpaw, 10-20 parts of witloof, 15-25 parts of bitter orange flower, 8-12 parts of hoveniae semoveniae semen, 8-12 parts of sealwort, Leaves of Hippophae L 10-20 parts, 10-18 parts of purple perilla seed, 5-10 parts of peach kernel.
The Xuancheng's pawpaw solid beverage for being used to improve constipation, it is prepared by the raw material of following parts by weight:A surname 25 parts of pawpaw, 15 parts of witloof, 20 parts of bitter orange flower, 10 parts of hoveniae semoveniae semen, 10 parts of sealwort, 15 parts of Leaves of Hippophae L, 14 parts of purple perilla seed, peach kernel 7 Part.
The Xuancheng's pawpaw solid beverage for being used to improve constipation, solid drink is made in addition auxiliary material after the raw material is extracted Material.
The Xuancheng's pawpaw solid beverage for being used to improve constipation, the auxiliary material is dextrin, lactose, starch, sucrose, grape The one or more of sugar and stevioside.
The Xuancheng's pawpaw solid beverage for being used to improve constipation, preparation method include the following steps:Take Xuancheng's pawpaw, chrysanthemum Lettuce, bitter orange flower, hoveniae semoveniae semen, sealwort, Leaves of Hippophae L, purple perilla seed, peach kernel medicinal material merge, and add water to cook twice, collecting decoction, and decompression is dense Relative density is the medicinal extract of 1.15-1.20 when being reduced to 65 DEG C, adds ethanol the percent by volume of alcohol content is reached 75-85%, is stirred, Stand, filtering, relative density is 1.25-1.30 when filtrate decompression is concentrated into 65 DEG C, and recycles ethanol, obtains concentrate, and spraying is dry Dry, solid beverage is made in addition auxiliary material.
The described Xuancheng's pawpaw solid beverage for being used to improve constipation, in preparation method step, decocting condition is:Add for the first time Water is 8-12 times of medicinal material weight and measures, and decocts 1-2h, adds 6-10 times that water is medicinal material weight to measure for the second time, decoction 1-2h.
The described Xuancheng's pawpaw solid beverage for being used to improve constipation, in preparation method step, spray drying condition is:Inlet air Temperature is 80-120 DEG C, and leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, and atomizing pressure is 0.2-0.4 megapascal, spraying Speed is 5-10ml/s.
The Xuancheng's pawpaw solid beverage for being used to improve constipation is preparing the application in improving constipation health products.
Beneficial effect:Xuancheng's pawpaw contains 19 kinds of amino acid, 18 kinds of mine trace elements, and vitamin C, together When also containing saponin, flavones, malic acid, oleanolic acid, citric acid, citric acid, tartaric acid, ascorbic acid, fumaric acid, tan Matter etc., containing catalase, phenol oxidase, oxidizing ferment, especially rich in hepatocuprein (SOD) and oleanolic acid.Its The content of SOD is impayable in all fruit in the world, and it is international single that the content of one gram of Xuancheng's pawpaw fresh fruit SOD is up to 3227 Position.SOD is the core substance of modern beauty beauty treatment product, can effectively eliminate superfluous free radical in vivo, promote body cell more Newly.Oleanolic acid has broad-spectrum antibacterial action, has the effects such as protect liver drop enzyme, promoting immunity, anti-inflammatory, reducing blood lipid blood glucose.Witloof is Medical and edible dual purpose plant, the modulated romaine lettuce of leaf, root contain synanthrin and aromatic substance, can obtain through refining alternative coffee, promote human consumption's device Official's activity.The aerial part and root of plant can hyoscine, Chinese medicine name is respectively witloof, cichory root, has clearing heat and detoxicating, and diuresis disappears It is swollen, stomach invigorating and other effects.The plant cold-resistant, drought-enduring, the ground such as sun-drenched field side, hillside are born in happiness.The country such as China has point Cloth.During bitter orange flower promoting the circulation of qi is wide, help digestion, resolving sputum.For the vexed distending pain of chest and abdomen, accumulation of food in the stomach and intes tine due to indigestion, phlegm and retained fluid, rectal prolapse, soothing the liver, and stomach, qi-regulating. It is vexed to control ruffian in the heart, abdominal distention, vomiting, few food.Hoveniae semoveniae semen is Rhamnaceae trifoliate orange Dulcis platymisciums north trifoliate orange Dulcis Hovenia dulcis Thunnb. trifoliate orange Dulcis Hovenia acerba Lindl. and comospore trifoliate orange Dulcis Hovenia trichocarpa Chun et Tsiang Mature seed.Also the useful fruit with rachis.Plant north trifoliate orange Dulcis, is distributed in China North China, northwest, East China, Central-South, southwestern And Taiwan.Plant trifoliate orange Dulcis, is distributed in the ground such as China North China, East China, Central-South, southwestern and Shaanxi, Gansu.Plant comospore trifoliate orange Dulcis, point It is distributed in China Zhejiang, Jiangxi, Hubei, Hunan, Guangdong and Guizhou.With relieving alcoholism, relieving restlessness of quenching the thirst, preventing or arresting vomiting, the work(of sharp stool and urine Effect.Drunk, polydipsia is cured mainly, is vomitted, difficulty in urination and defecation.Sealwort has tonifying spleen, the effect of moistening lung and production of body fluid.Leaves of Hippophae L cough-relieving apophlegmatic, disappears Foodization is stagnant, promoting blood circulation to remove blood stasis.For coughing with a lot of sputum, indigestion, dyspeptic abdominalgia, fall flutter the stasis of blood swell, blood stasis closed.Purple perilla seed has Raw meat, fresh adding, the effect rendered palatable.There is certain medical value at the same time, there is the effect of lower gas, clear phlegm, moistening lung, wide intestines.Purple perilla A kind of or efficient plant " preservative ".Contain a large amount of greases in purple perilla seed, oil yield is up to 45% or so, contains leukotrienes in oil 62.73%th, linoleic acid 15.43%, oleic acid 12.01%.Protein content accounts for 25% in seed, includes 18 kinds of amino acid, wherein Peace acid, the content of methionine is relied to be above high-protein plant Grain Production of Amaranthus.In addition with oryzanol, vitamin E, vitamin B1, black Alcohol, phosphatide etc..Peach kernel is rosaceous plant peach Prunus persica (L.) Batsch or mountain peach Prunus davidiana (Carr.) dry mature seed of Franch..Harvested after fruit maturation, remove pulp and nucleocapsid, taken out seed, dry.The whole nation Generally cultivate various regions.With promoting blood circulation, relax bowel, it is relieving cough and asthma the effect of.For closed dysmenorrhea, lump in the abdomen lump in the abdomen lump in the abdomen, lung carbuncle Acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.Xuancheng's pawpaw, witloof, bitter orange flower are monarch drug in a prescription in we, hoveniae semoveniae semen, sealwort, sand Spine leaf is ministerial drug, and purple perilla seed, peach kernel are adjuvant, and all medicine phases are closed, for improving constipation.
Embodiment
Form by the following examples, is described in further detail the above of the present invention again, but should not be by this The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal Belong to the scope of the present invention.
Embodiment:1:Take 20 parts of Xuancheng's pawpaw, 20 parts of witloof, 15 parts of bitter orange flower, 12 parts of hoveniae semoveniae semen, 8 parts of sealwort, Leaves of Hippophae L 20 10 parts of part, 10 parts of purple perilla seed, peach kernel medicinal materials merge, and add water to cook twice, and for the first time plus water is 10 times of amounts of medicinal material weight, is decocted 1.5h, adds 8 times that water is medicinal material weight to measure for the second time, decoction 1.5h, collecting decoction, is concentrated under reduced pressure at 0.07MPa, 60-70 DEG C To the medicinal extract that relative density at 65 DEG C is 1.15, adding 95% (v/v) ethanol to make alcohol content, stirring, it is small to stand 24 up to 75% (v/v) When, filtering, it is 1.25 that filtrate, which is concentrated under reduced pressure under the conditions of 0.07MPa, 65 DEG C to relative density at 65 DEG C, and recycles ethanol, Concentrate, concentrate is spray-dried to (condition is that inlet air temperature is 100 DEG C, and leaving air temp is 85 DEG C, temperature of charge 80 DEG C, atomizing pressure is 0.2 megapascal, spray velocity 5ml/s.), appropriate amount of starch is added, is prepared into solid beverage.
Embodiment 2:Take 30 parts of Xuancheng's pawpaw, 10 parts of witloof, 25 parts of bitter orange flower, 8 parts of hoveniae semoveniae semen, 12 parts of sealwort, Leaves of Hippophae L 10 5 parts of part, 18 parts of purple perilla seed, peach kernel medicinal materials merge, and add water to cook twice, and for the first time plus water is 8 times of amounts of medicinal material weight, is decocted 1h, adds 6 times that water is medicinal material weight to measure for the second time, decoction 1h, collecting decoction, and 65 are concentrated under reduced pressure at 0.07MPa, 60-70 DEG C DEG C when relative density be 1.20, add 95% (v/v) ethanol to make alcohol content up to 80% (v/v), stirring, stand 24 it is small when, filter, filter It is 1.30 that liquid, which is concentrated under reduced pressure under the conditions of 0.07MPa, 65 DEG C to relative density at 65 DEG C, and recycles ethanol, obtains concentrate, will (condition is that inlet air temperature is 110 DEG C, and leaving air temp is 80 DEG C, and temperature of charge is 70 DEG C, and atomizing pressure is for concentrate spray drying 0.3 megapascal, spray velocity 7.5ml/s.), appropriate dextrin is added, is prepared into solid beverage.
Embodiment 3:Take 25 parts of Xuancheng's pawpaw, 15 parts of witloof, 20 parts of bitter orange flower, 10 parts of hoveniae semoveniae semen, 10 parts of sealwort, Leaves of Hippophae L 15 7 parts of part, 14 parts of purple perilla seed, peach kernel medicinal materials merge, and add water to cook twice, and for the first time plus water is 12 times of amounts of medicinal material weight, is decocted 2h, adds 10 times that water is medicinal material weight to measure for the second time, decoction 2h, collecting decoction, and 65 are concentrated under reduced pressure at 0.07MPa, 60-70 DEG C DEG C when relative density be 1.20 medicinal extract, add 95% (v/v) ethanol to make alcohol content up to 85% (v/v), stirring, stand 24 it is small when, Filtering, it is 1.30 that filtrate, which is concentrated under reduced pressure under the conditions of 0.07MPa, 65 DEG C to relative density at 65 DEG C, and recycles ethanol, is obtained dense Concentrate, is spray-dried that (condition is that inlet air temperature is 120 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 90 DEG C, mist by contracting liquid Change pressure is 0.4 megapascal, spray velocity 10ml/s.), appropriate lactose is added, is prepared into solid beverage.
Embodiment 4:Influence of the Xuancheng's pawpaw solid beverage of the present invention to mice with constipation Small intestine advance activity
Animal:Healthy ICR mouse, half male and half female, weight 18-22g, is provided by Medical University Of Anhui's animal center.
Medicine and reagent:Xuancheng's pawpaw solid beverage of the present invention is prepared by above-described embodiment 3, is calculated with kilogram, dosage is 5g crude drugs/kg, this is low dosage, and dosage 10g crude drugs/kg is middle dosage, and dosage 20g crude drugs/kg is high dose.Phenolphthalein piece (Tab phenolphthaleinum sugar-tablet), Shandong Province Junan pharmaceutical factory, specification:100mg*100 pieces/box, lot number 20150506, dosage 0.3g/kg. Remaining reagent is that domestic analysis is pure.R-1132, Wujin pharmaceutical factory, 20140524.
Experiment process:ICR mouse 60 are taken, with R-1132 50m/kg gavage modelings, continuous 10 days, during which just Normal diet, forms Constipation Model, random packet, every group about 10, half male and half female, is divided into normal group, model group, positive drug group, High, medium and low three dosage groups of Xuancheng's pawpaw solid beverage of the present invention, administration are same as above, successive administration 14d, fasting for solids but not liquids before experiment 12h, 2h, is gavaged with the charcoal end Arabic gum suspension lml/g that volume fraction is 5%, is put to death after 20min respectively after the last administration Each group mouse, cut open the belly every mouse small intestine charcoal end displacement distance of measurement and total small intestinal length, is converted into charcoal end displacement distance and accounts for small intestine The percentage of total length, t test and judge group differences, the results are shown in Table 1.
Influence (n=10) of the Xuancheng's pawpaw solid beverage of the present invention of table 1 to mice with constipation Small intestine advance activity
Compared with model group, * * P<0.01*P<0.05, compared with positive drug group, ##P<0.01#P<0.05
As a result:Xuancheng's pawpaw solid beverage group of the present invention is obviously promoted mice with constipation small intestine push fortune compared with model group It is dynamic, promote gastrointestinal motility in mice, there is significant difference, compared with positive drug, the high middle dosage of Xuancheng's pawpaw solid beverage of the present invention Group has significant difference in terms of mice with constipation Small intestine advance activity is promoted, and effect is better than positive drug.

Claims (8)

1. a kind of Xuancheng's pawpaw solid beverage for being used to improve constipation, it is characterised in that it is prepared by the raw material of following parts by weight Obtain:20-30 parts of Xuancheng's pawpaw, 10-20 parts of witloof, 15-25 parts of bitter orange flower, 8-12 parts of hoveniae semoveniae semen, 8-12 parts of sealwort, Leaves of Hippophae L 10-20 parts, 10-18 parts of purple perilla seed, 5-10 parts of peach kernel.
2. the Xuancheng's pawpaw solid beverage according to claim 1 for being used to improve constipation, it is characterised in that it is by following weight The raw material of number is prepared:25 parts of Xuancheng's pawpaw, 15 parts of witloof, 20 parts of bitter orange flower, 10 parts of hoveniae semoveniae semen, 10 parts of sealwort, Leaves of Hippophae L 15 parts, 14 parts of purple perilla seed, 7 parts of peach kernel.
3. the Xuancheng's pawpaw solid beverage according to claim 1 or 2 for being used to improve constipation, it is characterised in that the raw material Solid beverage is made in addition auxiliary material after extracted.
4. the Xuancheng's pawpaw solid beverage according to claim 3 for being used to improve constipation, it is characterised in that the auxiliary material is paste Essence, lactose, starch, sucrose, the one or more of glucose and stevioside.
5. the Xuancheng's pawpaw solid beverage for being used to improve constipation described in claim 1 or 2, it is characterised in that preparation method includes Following steps:Take Xuancheng's pawpaw, witloof, bitter orange flower, hoveniae semoveniae semen, sealwort, Leaves of Hippophae L, purple perilla seed, peach kernel medicinal material to merge, add water to cook Twice, collecting decoction, relative density is the medicinal extract of 1.15-1.20 when being concentrated under reduced pressure into 65 DEG C, adds ethanol to make the volume of alcohol content Percentage reaches 75-85%, stirs, and stands, and filtering, relative density is 1.25-1.30 when filtrate decompression is concentrated into 65 DEG C, and is recycled Ethanol, obtains concentrate, spray drying, and solid beverage is made in addition auxiliary material.
6. the Xuancheng's pawpaw solid beverage according to claim 5 for being used to improve constipation, it is characterised in that preparation method step In, decocting condition is:Add 8-12 times that water is medicinal material weight to measure for the first time, decoct 1-2h, second plus water are medicinal material weight 6-10 times is measured, and decocts 1-2h.
7. the Xuancheng's pawpaw solid beverage according to claim 5 for being used to improve constipation, it is characterised in that preparation method step In, spray drying condition is:Inlet air temperature is 80-120 DEG C, and leaving air temp is 80-90 DEG C, and temperature of charge is 70-90 DEG C, atomization Pressure is 0.2-0.4 megapascal, spray velocity 5-10ml/s.
8. Xuancheng's pawpaw solid beverage the answering in improvement constipation health products are prepared for being used to improve constipation of claim 1 or 2 With.
CN201711154306.2A 2017-11-20 2017-11-20 A kind of Xuancheng's pawpaw solid beverage for being used to improve constipation Withdrawn CN107897615A (en)

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CN109007138A (en) * 2018-10-16 2018-12-18 安徽明珍堂养生品有限公司 A kind of concentration tea and preparation method thereof with qi-supplementing, blood-engendering effect
CN109007137A (en) * 2018-10-15 2018-12-18 安徽明珍堂养生品有限公司 A kind of concentration tea and preparation method thereof improving hyperglycemia

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CN106994141A (en) * 2016-01-25 2017-08-01 北京斯利安药业有限公司 It is a kind of to treat Chinese medicine composition of constipation and preparation method thereof
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Publication number Priority date Publication date Assignee Title
CN108935814A (en) * 2018-10-15 2018-12-07 安徽明珍堂养生品有限公司 A kind of clearing damp invigorating the spleen concentration tea and preparation method thereof
CN109007137A (en) * 2018-10-15 2018-12-18 安徽明珍堂养生品有限公司 A kind of concentration tea and preparation method thereof improving hyperglycemia
CN109007138A (en) * 2018-10-16 2018-12-18 安徽明珍堂养生品有限公司 A kind of concentration tea and preparation method thereof with qi-supplementing, blood-engendering effect

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