CN107875434A - 一种新型防粘连藻酸盐敷料 - Google Patents
一种新型防粘连藻酸盐敷料 Download PDFInfo
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- 229920000615 alginic acid Polymers 0.000 title claims abstract description 36
- 235000010443 alginic acid Nutrition 0.000 title claims abstract description 36
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 title claims abstract description 31
- 229940072056 alginate Drugs 0.000 title claims abstract description 31
- 239000000835 fiber Substances 0.000 claims abstract description 28
- 239000002253 acid Substances 0.000 claims abstract description 22
- 238000000034 method Methods 0.000 claims abstract description 7
- 238000010041 electrostatic spinning Methods 0.000 claims abstract description 4
- 238000002166 wet spinning Methods 0.000 claims abstract description 4
- 239000004744 fabric Substances 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 239000004626 polylactic acid Substances 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 229960001126 alginic acid Drugs 0.000 description 5
- 239000000783 alginic acid Substances 0.000 description 5
- 150000004781 alginic acids Chemical class 0.000 description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 239000002390 adhesive tape Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 159000000007 calcium salts Chemical class 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- -1 alginic acid salt Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0206—Adhesive bandages or dressings with fluid retention members with absorbent fibrous layers, e.g. woven or non-woven absorbent pads or island dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0246—Adhesive bandages or dressings characterised by the skin-adhering layer
- A61F13/0253—Adhesive bandages or dressings characterised by the skin-adhering layer characterized by the adhesive material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/50—Lubricants; Anti-adhesive agents
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Abstract
本发明公开了一种新型防粘连藻酸盐敷料，涉及医疗器械领域，由上、下两层结构组成，并紧密粘结，上层结构为聚乳酸纤维膜层，由聚乳酸纤维构成，所述聚乳酸纤维膜层由静电纺丝技术制得，所述下层结构为海藻酸盐无纺布层，由海藻酸盐纤维组成，所述海藻酸盐无纺布层由湿法纺丝和针刺工艺制得，所述聚乳酸纤维膜层均匀分布有直径为0.5μm~1μm的微孔。本发明不仅具有较强的吸收渗液性能而且还具有防止伤口粘连从而防止创面造成二次损伤。
Description
技术领域
本发明涉及医疗器械领域，具体属于一种新型防粘连藻酸盐敷料。
背景技术
海藻酸盐敷料是海藻中提炼出的海藻酸，是一种类纤维素的不溶解多糖。制作过程中海藻酸被转换成一种钙盐。在与创面渗液接触时，海藻酸的钙盐能通过离子间交换，使不溶解性海藻酸盐钙变为可溶性藻酸钠，并释放出钙，具有极强的吸收性。这保证了伤口湿性愈合环境，延长换药时间，同时使伤口内的坏死组织自溶。海藻酸盐中的钙离子在伤口表面形成一层网状凝胶有助于促进止血。但现有的海藻酸盐敷料一般由藻酸盐层、医用胶带组成。海藻酸盐敷料吸液后需要用绷带再次固定，或伤口渗透液渗透到医用胶带上；同时导致海藻酸盐层容易与创面发生粘连，造成创面二次损伤。
发明内容
本发明的目的是为了满足吸收伤口渗液又不粘连伤口的目的，提供了一种新型防粘连藻酸盐敷料。
为了实现上述目的，本发明提供的一种新型防粘连藻酸盐敷料，由上、下两层结构组成，并紧密粘结，上层结构为聚乳酸纤维膜层，由聚乳酸纤维构成，所述聚乳酸纤维膜层由静电纺丝技术制得，所述下层结构为海藻酸盐无纺布层，由海藻酸盐纤维组成，所述海藻酸盐无纺布层由湿法纺丝和针刺工艺制得，所述聚乳酸纤维膜层均匀分布有直径为0.5μm~1μm的微孔。
优选的，所述聚乳酸纤维膜层的厚度为2μm~5μm，所述聚乳酸纤维直径为200nm~1μm。
优选的，所述海藻酸盐无纺布层的厚度为1mm~3mm，克重为110g/m2~150g/m2。
本发明的有益效果为：不仅具有较强的吸收渗液性能而且还具有防止伤口粘连从而防止创面造成二次损伤。
附图说明
图1为本发明一种新型防粘连藻酸盐敷料的结构示意图；
附图标记说明：1、聚乳酸纤维膜层；2、海藻酸盐无纺布层。
具体实施方式
下面结合附图对本发明作进一步描述。以下实施例仅用于更加清楚地说明本发明的技术方案，而不能以此来限制本发明的保护范围。
如图所示：提供的一种新型防粘连藻酸盐敷料，由上、下两层结构组成，并紧密粘结，上层结构为聚乳酸纤维膜层1，由聚乳酸纤维构成，所述聚乳酸纤维膜层1由静电纺丝技术制得，所述下层结构为海藻酸盐无纺布层2，由海藻酸盐纤维组成，所述海藻酸盐无纺布层2由湿法纺丝和针刺工艺制得；所述聚乳酸纤维膜层1的厚度为2μm~5μm，所述聚乳酸纤维直径为200nm~1μm；所述聚乳酸纤维膜层1均匀分布有直径为0.5μm~1μm的微孔；所述海藻酸盐无纺布层2的厚度为1mm~3mm，克重为110g/m2~150g/m2。
最后应说明的是：显然，上述实施例仅仅是为清楚地说明本发明所作的举例，而并非对实施方式的限定。对于所属领域的普通技术人员来说，在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无需也无法对所有的实施方式予以穷举。而由此所引申出的显而易见的变化或变动仍处于本发明的保护范围之中。
Claims (3)
1.一种新型防粘连藻酸盐敷料，其特征在于，由上、下两层结构组成，并紧密粘结，上层结构为聚乳酸纤维膜层，由聚乳酸纤维构成，所述聚乳酸纤维膜层由静电纺丝技术制得，所述下层结构为海藻酸盐无纺布层，由海藻酸盐纤维组成，所述海藻酸盐无纺布层由湿法纺丝和针刺工艺制得，所述聚乳酸纤维膜层均匀分布有直径为0.5μm~1μm的微孔。
2.根据权利要求1所述的一种新型防粘连藻酸盐敷料，其特征在于，所述聚乳酸纤维膜层的厚度为2μm~5μm，所述聚乳酸纤维直径为200nm~1μm。
3.根据权利要求1所述的一种新型防粘连藻酸盐敷料，其特征在于，所述海藻酸盐无纺布层的厚度为1mm~3mm，克重为110g/m2~150g/m2。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110090316A (zh) * | 2019-04-25 | 2019-08-06 | 广东泰宝医疗科技股份有限公司 | 一种防黏连驻极体敷料及其制备方法 |
| CN110180013A (zh) * | 2019-05-31 | 2019-08-30 | 上海纳米技术及应用国家工程研究中心有限公司 | 覆膜型医用烧伤防粘连型纱布绷带的制备方法及其产品和应用 |
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| CN107469131A (zh) * | 2017-08-29 | 2017-12-15 | 北京化工大学常州先进材料研究院 | 一种海藻酸钙生物复合医用敷料及其制备方法 |
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2017
- 2017-12-18 CN CN201711362116.XA patent/CN107875434A/zh active Pending
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110090316A (zh) * | 2019-04-25 | 2019-08-06 | 广东泰宝医疗科技股份有限公司 | 一种防黏连驻极体敷料及其制备方法 |
| CN110180013A (zh) * | 2019-05-31 | 2019-08-30 | 上海纳米技术及应用国家工程研究中心有限公司 | 覆膜型医用烧伤防粘连型纱布绷带的制备方法及其产品和应用 |
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