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WO2011084326A3 - Hemostatic agents and wound dressings - Google Patents

Hemostatic agents and wound dressings

Info

Publication number
WO2011084326A3
WO2011084326A3 PCT/US2010/059497 US2010059497W WO2011084326A3 WO 2011084326 A3 WO2011084326 A3 WO 2011084326A3 US 2010059497 W US2010059497 W US 2010059497W WO 2011084326 A3 WO2011084326 A3 WO 2011084326A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
wound
hemostatic
site
disclosed
blood
Prior art date
Application number
PCT/US2010/059497
Other languages
French (fr)
Other versions
WO2011084326A2 (en )
Inventor
Fangxiao Yang
Original Assignee
Resodyn Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/60Liquid-swellable gel-forming materials, e.g. super-absorbents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00365Plasters use
    • A61F2013/00463Plasters use haemostatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F2013/00361Plasters
    • A61F2013/00365Plasters use
    • A61F2013/00463Plasters use haemostatic
    • A61F2013/00472Plasters use haemostatic with chemical means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Abstract

Hemostatic compositions are disclosed comprising hydrogels and polyglucosamines and/or polyglucosamine derivatives. The hemostatic compositions can also contain coagulation acceleration agents and antibiotics, antifungals, anti-infectives, antimicrobials, anti-inflammatories, analgesics, and antihistamines. A method of promoting blood clotting is disclosed which comprises contacting blood with a disclosed hemostatic composition. Wound dressings are comprised of the disclosed hemostatic compositions and a substrate such as fabrics made from natural and/or synthetic fibers. The wound dressings containing the disclosed hemostatic compositions have high water adsorption capacity and good bleeding control and also exhibit strong adhesion to wet, bloody wounds. The wound dressings typically adhere to, or are held against, or placed into a wound site, to seal the wound site, to accelerate blood clot formation at the wound site, to reinforce clot formation at the wound site and prevent bleed out from the wound site, and to substantially stop the flow of blood out of the wound site.
PCT/US2010/059497 2009-12-21 2010-12-08 Hemostatic agents and wound dressings WO2011084326A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US28465209 true 2009-12-21 2009-12-21
US61/284,652 2009-12-21

Publications (2)

Publication Number Publication Date
WO2011084326A2 true WO2011084326A2 (en) 2011-07-14
WO2011084326A3 true true WO2011084326A3 (en) 2011-10-20

Family

ID=44306021

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/059497 WO2011084326A3 (en) 2009-12-21 2010-12-08 Hemostatic agents and wound dressings

Country Status (1)

Country Link
WO (1) WO2011084326A3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130224712A1 (en) * 2012-02-24 2013-08-29 Bradford L. Day Medical training kits and methods to simulate treatment of uncontrolled hemorrhage
KR101432276B1 (en) * 2013-02-06 2014-08-21 주식회사 이노테라피 Animal Model to Assess Hemostatic Adhesives Ability Inducing Hemorrhage of Common Carotid Artery (CCA) or Superior Sagittal Sinus (SSS) and Use of the Same
WO2018005145A1 (en) * 2016-06-28 2018-01-04 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706279B1 (en) * 2000-10-17 2004-03-16 Pharma Mag Inc. Wound dressing
US20060292207A1 (en) * 2005-06-22 2006-12-28 Atomic Energy Council - Institute Of Nuclear Energy Research Chitosan based dressing
KR20080018360A (en) * 2006-08-24 2008-02-28 대화제약 주식회사 A wound-healing dressing patch with hydrogel layer containing chitosan
US20090035356A1 (en) * 2005-09-06 2009-02-05 Trung Bui-Khac Modified biodegradable polymers, preparation and use thereof for making biomaterials and dressings
US20090043235A1 (en) * 2007-08-08 2009-02-12 Medical And Pharmaceutical Industry Technology And Development Center Et Al. Composite dressing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706279B1 (en) * 2000-10-17 2004-03-16 Pharma Mag Inc. Wound dressing
US20060292207A1 (en) * 2005-06-22 2006-12-28 Atomic Energy Council - Institute Of Nuclear Energy Research Chitosan based dressing
US20090035356A1 (en) * 2005-09-06 2009-02-05 Trung Bui-Khac Modified biodegradable polymers, preparation and use thereof for making biomaterials and dressings
KR20080018360A (en) * 2006-08-24 2008-02-28 대화제약 주식회사 A wound-healing dressing patch with hydrogel layer containing chitosan
US20090043235A1 (en) * 2007-08-08 2009-02-12 Medical And Pharmaceutical Industry Technology And Development Center Et Al. Composite dressing

Also Published As

Publication number Publication date Type
WO2011084326A2 (en) 2011-07-14 application

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