CN107854652A

CN107854652A - A kind of Chinese medicine composition for treating prostatic disorders and preparation method thereof

Info

Publication number: CN107854652A
Application number: CN201711081802.XA
Authority: CN
Inventors: 王超
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-11-07
Filing date: 2017-11-07
Publication date: 2018-03-30

Abstract

The invention discloses a kind of Chinese medicine composition for treating prostatic disorders and preparation method thereof, belong to the field of Chinese medicines.The Chinese medicine composition is made up of following raw material medicaments：Son, chingma abutilon seed, pointed at both ends, centipede, mole cricket, earthworm, pyrrosia lingua, Bi Collettii, desmodium, Poria cocos, Chinese lobelia, honeysuckle, kelp, marine alga, Rhizoma Sparganii, Wen Shu, sliced CORNUS CERVI, spina gleditsiae, first pearl, borneol, diaphragma juglandis, radix glycyrrhizae, Hedyotidis Diffusae and leech are practiced in oyster, car fare, Lu Bazi, river.Method comprises the following steps：Raw material is crushed, decocted 2~3 times, merges decoction liquor, filtration, is concentrated under reduced pressure into liquid extract, is dried under reduced pressure, micronization crushes.The Chinese medicine composition of the present invention can effectively improve prostatitis, hyperplasia of prostate, hypertrophy of the prostate patient's urine urgency-frequency, dysuria, the urinary incontinence, gonococcus property prostate, urethra bifurcated, sex dysfunction, epididymitis, the symptom such as the retention of urine and blood urine.

Description

A kind of Chinese medicine composition for treating prostatic disorders and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines；Specifically, it is related to a kind of Chinese medicine composition for treating prostatic disorders, and its should The preparation method of Chinese medicine composition.

Background technology

Prostatitis is the common disease of Urology Surgery, and its Etiological is probably pathogenic infection, caused urinary function Obstacle；Hypertrophy of the prostate is prostate abnormalities proliferative disease, is common in gerontal patient, and easilys lead to the hair of the retention of urine It is raw.At present, doctor trained in Western medicine is treated frequently with antibiotic, hormone medicine, although can be taken effect in the short time, is also easy to produce pair Effect, and easily recurrence；And in general drug therapy can only relief of symptoms, it is difficult to fundamentally cure, and Long-term taking medicine may be used also Urethra burden can be increased, cause reflex voiding difficult, make the state of an illness more serious, or even need to take operative treatment.

The content of the invention

It is an object of the invention to provide a kind of Chinese medicine composition for treating prostatitis and hypertrophy of the prostate.

To achieve the above object, present invention employs following technical scheme：

A kind of Chinese medicine composition for treating prostatic disorders, the Chinese medicine composition are made up of following raw material medicaments：Oyster, car fare Son, chingma abutilon seed, pointed at both ends, centipede, mole cricket, earthworm, pyrrosia lingua, Bi Collettii, desmodium, Poria cocos, Chinese lobelia, gold are practiced in son, Lu Bazi, river Honeysuckle flower, kelp, marine alga, Rhizoma Sparganii, Wen Shu, sliced CORNUS CERVI, spina gleditsiae, first pearl, borneol, diaphragma juglandis, radix glycyrrhizae, Hedyotidis Diffusae, leech.

Preferably, the Chinese medicine composition is made up of the bulk drug of following weight parts:The sub- 15g of oyster 20g~40g, car fare~ Sub- 15g~35g, chingma abutilon seed 15g~35g, 15g~35g pointed at both ends, centipede 2, mole cricket are practiced in 35g, reed Ba Zi 15g~35g, river 10g~30g, earthworm 5g~25g, pyrrosia lingua 15g~35g, Bi Collettiis 15g~35g, desmodium 15g~35g, Poria cocos 15g~35g, half Side lotus 10g~30g, honeysuckle 20g~40g, kelp 20g~40g, marine alga 20g~40g, Rhizoma Sparganii 10g~30g, literary art 10g~ 30g, sliced CORNUS CERVI 15g~35g, spina gleditsiae 15g~35g, first pearl 10g~30g, borneol 5g~20g, diaphragma juglandis 10g~30g, radix glycyrrhizae 5g~20g, Hedyotidis Diffusae 20g~40g, leech 10g~30g.

It is highly preferred that the Chinese medicine composition is made up of the bulk drug of following weight parts:The Chinese medicinal compound has following proportioning Bulk drug composition：Sub- 20g~30g, chingma abutilon seed are practiced in the sub- 20g~30g of oyster 25g~35g, car fare, reed Ba Zi 20g~30g, river 20g~30g, 20g~30g pointed at both ends, centipede 2, mole cricket 15g~25g, earthworm 10g~20g, pyrrosia lingua 20g~30g, Bi Collettiis 20g~30g, desmodium 20g~30g, Poria cocos 20g~30g, Chinese lobelia 15g~25g, honeysuckle 25g~35g, kelp 25g~ 35g, marine alga 25g~35g, Rhizoma Sparganii 15g~25g, literary art 15g~25g, sliced CORNUS CERVI 20g~30g, spina gleditsiae 20g~30g, first pearl 15g~25g, borneol 5g~15g, diaphragma juglandis 15g~25g, radix glycyrrhizae 5g~15g, Hedyotidis Diffusae 25g~35g, leech 15g~ 25g。

It is highly preferred that the Chinese medicine composition is made up of the bulk drug of following weight parts:The Chinese medicinal compound has following proportioning Bulk drug composition：Sub- 25g, chingma abutilon seed 25g, 25g pointed at both ends, centipede 2 are practiced in the sub- 25g of oyster 30g, car fare, reed Ba Zi 25g, river Bar, mole cricket 20g, earthworm 15g, pyrrosia lingua 25g, Bi Collettiis 25g, desmodium 25g, Poria cocos 25g, Chinese lobelia 20g, honeysuckle 30g, kelp 30g, marine alga 30g, Rhizoma Sparganii 20g, literary art 20g, sliced CORNUS CERVI 25g, spina gleditsiae 25g, first pearl 20g, borneol 10g, diaphragma juglandis 20g, radix glycyrrhizae 10g, Hedyotidis Diffusae 30g, leech 20g.

It is a further object of the invention to provide a kind of system for the Chinese medicine composition for treating prostatitis and hypertrophy of the prostate Preparation Method.

A kind of preparation method for the Chinese medicine composition for treating prostatitis and hypertrophy of the prostate, comprises the following steps：By original Feed powder is broken, decocts 2~3 times, merges decoction liquor, filtration, is concentrated under reduced pressure into liquid extract, is dried under reduced pressure, micronization crushes.

Further limit, in the decoction process plus 4~15 times are measured water.

Further limit, decoct extraction 1~3 hour every time.

Further limit, it is described to be concentrated under reduced pressure into relative density about 1.20~1.40 (50 DEG C~70 DEG C) liquid extract.

Further limit, the temperature being dried under reduced pressure is 60~80 DEG C.

Further limit, it is 800~1000 mesh that the micronization, which is crushed to fineness,.

The Chinese medicine composition of the present invention, can add customary adjuvant (starch, vegetable oil etc.), be made according to a conventional method clinically Acceptable tablet, pulvis, capsule or granule.

Instructions of taking：Pulvis, three times a day, a 6.5g, one month is a course for the treatment of.

The present invention is Chinese medicine composition, is made according to a conventional method, clinically acceptable pulvis, or particle, capsule is preferred For pulvis.

Chinese medicine oyster --- the major function of the present invention：Return liver, courage, kidney channel.It is calming the liver；It is transquilization with heavy material；Softening and resolving hard mass； Restrain astringent or styptic treatment for spontaneous sweating.Main dizziness and tinnitus；Insomnia of palpitating with fear；Scrofula goiter and tumor；Abdominal mass lump in the abdomen；Spontaneous sweating；Seminal emission；Uterine bleeding；Under band.

Car fare --- major function：Gonorrhoea renal shutdown, summer heat damp diarrhea, hot eyes is dim-sighted, phlegm-heat cough.

Lu Bazi --- major function：Cold hernia, abdomen side of body turgor, the disturbance of lower legs due to pathogenic cold and dampness, the kidney deficiency soreness of waist, impotence.It is cold for kidney void, Cold and pain in the lower abdomen, herria, the disturbance of lower legs due to pathogenic cold and dampness.

Practice son in river --- major function：For chest side of body, abdominal distention, colic, abdominal pain due to enterositosis.

Chingma abutilon seed --- major function：Gonorrhoea, oedema, constipation, galactostasis.

It is pointed at both ends --- major function：For wind-cold-dampness arthralgia, spasm of limbs, arthralgia, carbuncle turgescence canker.

Centipede --- major function：For liver wind agitation, spasm twitch, child convulsion, middle air port crooked, hemiplegia, break Cold, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula, snake bite and insect sting.

Mole cricket --- major function：Inducing diuresis for removing edema.For diseases such as oedema, ascites, difficult urinations.

Earthworm --- major function：Clearing heat for calming endogenous wind, for high fever frightened epilepsy, demented.It is clearing and activating the channels and collaterals, for bi Zheng and half body not Then.Reducing fever and causing diuresis, for bladder heat stagnation, difficult urination or renal shutdown are obstructed.

Pyrrosia lingua --- major function：Promoting diuresis for stranguria, clearing lung-heat expel the heat-evil.Control leaching pain, hematuria, lithangiuria, ephritis, uterine bleeding, dysentery Disease, cough with lung heat, chronic bronchitis, metal-inflicted wound, ulcer.

Bi Collettii --- major function：Drenched for cream, gonorrhoea, leukorrhea, arthralgia pain due to rheumatism, articular instability, lumbocrural pain.

Desmodium --- major function：Liver and gall and stone in urinary system；Heat gonorrhea, nephritic dropsy, jaundice with damp-heat pathogen, sore carbuncle swells, Venomous snake bite, traumatic injury.

Poria cocos --- major function：For oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea is confused and worried, shies Throb with fear insomnia.

Chinese lobelia --- major function：Clearing heat and detoxicating, inducing diuresis to remove edema effect, control venomous snake bite, cirrhotic ascites, late period blood Fluke disease ascites, appendicitis and other effects.

Honeysuckle --- major function：Affection of exogenous wind-heat or warm disease heating, heatstroke, toxic-heat and blood stasis, carbuncle swells furunculosis, larynx numbness are more Kind infectious diseases.

Kelp --- major function：Softening and resolving hard mass, dissolving phlegm, Li Shui.For goiter and tumor, scrofula, testiclar gall, phlegm and retained fluid oedema.

Marine alga --- major function：Scrofula；Goiter and tumor；Accumulation；Oedema；Tinea pedis；Testiclar gall；(Epileptic is ruined) hernia.

Rhizoma Sparganii --- major function：For abdominal mass lump in the abdomen, dysmenorrhoea, blood stasis closed, chest impediment and cardialgia, dyspepsia distending pain.

Literary art --- major function：Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis are antiabortive.For spleen eating less, abdominal distention diarrhea, phlegm Drink feel dizzy and heart palpitations, oedema, spontaneous perspiration, fetal irritability.

Sliced CORNUS CERVI --- major function：Kidney deficiency spinal column crymodynia, impotence and seminal emission, uterine bleeding, leukorrhea, frequent micturition urinate more, cloudy subcutaneous ulcer sore, The symptoms such as acute mastitis swells and ache, beaten the stasis of blood swell, arthralgia and myalgia.

Spina gleditsiae --- major function：Sterilize purulence；Search wind；Desinsection.Main swollen ulcer drug；Scrofula；Sore rash stubborn dermatitis；Postpartum lacks Breast；Retention of afterbirth；Pestilential wind.

First pearl --- major function：Ulcer sore swells are controlled, wind-cold-dampness arthralgia, amenorrhea, alactation, are had blood in stool.

Borneol --- major function：Lead to all keys, dissipate stagnated fire, go screen improving eyesight, swelling and pain relieving, heat-clearing dissipates poison, dissipate fire removing toxic substances.Control Mammary gland caking, apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm fan, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh is also Screen film, enterobiasis.

Diaphragma juglandis --- major function：For lingering diarrhea of passing out semen, frequent urination and enuresis, uterine bleeding, under band, diarrhea, dysentery.

Radix glycyrrhizae --- major function：For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction Anxious pain, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.

Hedyotidis Diffusae --- major function：It is clearing heat and detoxicating；Dampness removing.Main dyspnea and cough due to lung-heat；Abscess of throat；Acute appendicitis；Furuncle sore； Venomous snake bite；Puckery pain of heat gonorrhea；Oedema；Dysentery；Enteritis；Jaundice with damp-heat pathogen；Cancerous swelling.

Leech --- major function：The diseases such as menstruation apolipsis, abdominal mass are suffered from abdominal pain, store blood, traumatic blood stasis is had a pain, carbuncle swells erysipelas.

Prostatitis, hyperplasia (hypertrophy) are that the evil damp and hot inflow of diseases caused by external factors poison is pented up or eating and drinking without temperance in traditional Chinese medical science category stranguria with turbid discharge category, It is damp and hot, damp and hot unclear to make life, the present invention is using oyster, marine alga, kelp, Hedyotidis Diffusae, honeysuckle as monarch drug in a prescription；Because of prostatic category Liver Channel, therefore using oyster as monarch drug in a prescription, because the general medicine in position is difficult to reach sick institute, therefore using above-mentioned 5 Chinese medicine as monarch drug in a prescription, dissipated with softening hard masses Knot, clearing heat and promoting diuresis, removing toxic substances.Son, chingma abutilon seed, pointed at both ends, pyrrosia lingua, Bi Collettii, desmodium, Poria cocos, soap are practiced in car fare, Lu Bazi, river Thorn, Chinese lobelia, sliced CORNUS CERVI are ministerial drug, inducing diuresis for removing edema, apocenosis removing toxic substances of analgesia；Adjutant with centipede, leech, mole cricket, earthworm, first pearl, divert one's attention Wood, Rhizoma Sparganii, Wen Shu, to stimulate the menstrual flow, and blood-breaking promoting blood circulation and removing blood stasis, the power for the silt that disappears, up to sick institute, to make with borneol, pungent scattered power is to help medicine Effect, with radix glycyrrhizae coordinating the drug actions of a prescription.

Compared with prior art, the invention has the advantages that：

The Chinese medicine composition of the present invention can effectively improve prostatitis, hyperplasia of prostate, hypertrophy of the prostate Urinary pollakiuria It is anxious, dysuria, the urinary incontinence, gonococcus property prostate, urethra bifurcated, sex dysfunction, epididymitis, the disease such as the retention of urine and blood urine Shape.

The present invention can provide clinical efficacy, improve the quality of life of patient.

Clinical practice of the present invention has no side effect safely, has no adverse reaction, and medication is curative for effect.

Embodiment

Embodiment one：Present embodiment treatment prostatic disorders Chinese medicine composition by following raw material medicaments form by The bulk drug composition of following weight parts:The Chinese medicinal compound is made up of the bulk drug of following proportioning：The sub- 25g of oyster 30g, car fare, Sub- 25g, chingma abutilon seed 25g, 25g pointed at both ends, centipede 2, mole cricket 20g, earthworm 15g, pyrrosia lingua 25g, Bi Collettii are practiced in reed Ba Zi 25g, river 25g, desmodium 25g, Poria cocos 25g, Chinese lobelia 20g, honeysuckle 30g, kelp 30g, marine alga 30g, Rhizoma Sparganii 20g, literary art 20g, deer Cornual plate 25g, spina gleditsiae 25g, first pearl 20g, borneol 10g, diaphragma juglandis 20g, radix glycyrrhizae 10g, Hedyotidis Diffusae 30g, and leech 20g.

The treatment prostatitis of present embodiment and the preparation method of the Chinese medicine composition of hypertrophy of the prostate are by following steps Suddenly carry out：Methods described is to crush raw material, adds 10 times of amount decoctings to boil 2 times, decocts extraction 2 hours every time, merge decoction liquor, Filtration, being concentrated under reduced pressure into relative density about 1.20~1.40, (50 DEG C~70 DEG C liquid extracts, are dried under reduced pressure, micronization at 70 DEG C Smashing fineness is 1000 mesh.

1st, clinical data

500 Li Lai andrologies male patients, clinic has the symptoms such as urine urgency-frequency, odynuria, dysuria, through serum acid phosphatase Enzymatic determination, cystoscopy, Residual urine measurement, it is diagnosed as male prostate hypertrophy patient, one full year of life at age 50 to 65.

2nd, treatment method

What the Chinese medicine composition that 500 hypertrophy of the prostate patients take the offer of the specific embodiment of the invention one was prepared Extract, 3 times a day, 6.5 grams/times, it one month is a course for the treatment of to take, while no smoking and drinking, is avoided cold and uncooked food, follow-up 1 to 3 month.

3rd, treatment results

The present invention Traditional Chinese medicine compound composition that specifically embodiment one provides is taken after 2 months, the treatment results such as institute of table 1 Show：

The Traditional Chinese medicine compound composition of table 1 treats the clinical efficacy situation of hypertrophy of the prostate

Cure (example)	Effective (example)	Effectively (example)	Invalid (example)	Total effective rate
					350	106	42	2	99.6%

Shown by above clinical trial results, after taking Traditional Chinese medicine compound composition provided by the invention, hypertrophy of the prostate The inspection of patient's B ultrasound is known prostate volume and is obviously reduced, and controlled micturition is difficult, the urinary incontinence, the clinical symptom disappearance such as the retention of urine and blood urine, And the prolapse of the anus caused by hypertrophy of the prostate, have blood in stool disappears with symptoms such as abdominal tendernesses, and total effective rate is up to more than 99.6%. And follow-up 2 months, no recurrence rate, unobstructed micturition, dietetic life rule.

The Traditional Chinese medicine compound composition for the treatment of prostate hyperplasia provided by the invention, according to traditional Chinese medical theory, for male The pathogenesis of hypertrophy of the prostate, scientific compatible combination is carried out using diagnosis and treatment, each taste medicine cooperates with promotion in prescription, can be from root Recover prostate physiological function in sheet, there is the effect of obvious, and clinically have no adverse reaction, be expected to develop into before preventing and treating The medicine of row gland hypertrophy disease.

Claims

A kind of 1. Chinese medicine composition for treating prostatic disorders, it is characterised in that：The Chinese medicinal compound has the raw material of following proportioning Medicine forms：Sub- 15g~the 35g of oyster 20g~40g, car fare, reed Ba Zi 15g~35g, the sub- 15g~35g of river white silk, chingma abutilon seed 15g~ 35g, 15g~35g pointed at both ends, centipede 2, mole cricket 10g~30g, earthworm 5g~25g, pyrrosia lingua 15g~35g, Bi Collettiis 15g~ 35g, desmodium 15g~35g, Poria cocos 15g~35g, Chinese lobelia 10g~30g, honeysuckle 20g~40g, kelp 20g~40g, sea Algae 20g~40g, Rhizoma Sparganii 10g~30g, literary art 10g~30g, sliced CORNUS CERVI 15g~35g, spina gleditsiae 15g~35g, first pearl 10g~ 30g, borneol 5g~20g, diaphragma juglandis 10g~30g, radix glycyrrhizae 5g~20g, Hedyotidis Diffusae 20g~40g, leech 10g~30g.
A kind of 2. Chinese medicine composition for treating prostatic disorders according to claim 1, it is characterised in that：The Chinese medicinal compound It is made up of the bulk drug of following proportioning：Sub- 20g~the 30g of oyster 25g~35g, car fare, reed Ba Zi 20g~30g, the river sub- 20g of white silk~ 30g, chingma abutilon seed 20g~30g, 20g~30g pointed at both ends, centipede 2, mole cricket 15g~25g, earthworm 10g~20g, pyrrosia lingua 20g~ 30g, Bi Collettiis 20g~30g, desmodium 20g~30g, Poria cocos 20g~30g, Chinese lobelia 15g~25g, honeysuckle 25g~35g, elder brother Cloth 25g~35g, marine alga 25g~35g, Rhizoma Sparganii 15g~25g, literary art 15g~25g, sliced CORNUS CERVI 20g~30g, spina gleditsiae 20g~ 30g, first pearl 15g~25g, borneol 5g~15g, diaphragma juglandis 15g~25g, radix glycyrrhizae 5g~15g, Hedyotidis Diffusae 25g~35g, leech 15g~25g.
A kind of 3. Chinese medicine composition for treating prostatic disorders according to claim 1, it is characterised in that：The Chinese medicinal compound It is made up of the bulk drug of following proportioning：The sub- 25g of oyster 30g, car fare, reed Ba Zi 25g, river practice sub- 25g, chingma abutilon seed 25g, pointed at both ends 25g, centipede 2, mole cricket 20g, earthworm 15g, pyrrosia lingua 25g, Bi Collettiis 25g, desmodium 25g, Poria cocos 25g, Chinese lobelia 20g, gold and silver Flower 30g, kelp 30g, marine alga 30g, Rhizoma Sparganii 20g, literary art 20g, sliced CORNUS CERVI 25g, spina gleditsiae 25g, first pearl 20g, borneol 10g, divert one's attention Wooden 20g, radix glycyrrhizae 10g, Hedyotidis Diffusae 30g, leech 20g.
A kind of 4. system for the Chinese medicine composition for treating prostatic disorders according to any one claim in claim 1-3 Preparation Method, it is characterised in that：Methods described is to crush raw material, is decocted 2~3 times, merges decoction liquor, filtration, is concentrated under reduced pressure into Liquid extract, it is dried under reduced pressure, micronization crushes.
5. a kind of preparation method for the Chinese medicine composition for treating prostatic disorders according to claim 4, it is characterised in that decoct During boiling plus 4~15 times are measured water.
6. a kind of preparation method for the Chinese medicine composition for treating prostatic disorders according to claim 4, it is characterised in that every It is secondary to decoct extraction 1~3 hour.
A kind of 7. preparation method for the Chinese medicine composition for treating prostatic disorders according to claim 4, it is characterised in that institute State and be concentrated under reduced pressure into relative density about 1.20~1.40 (50 DEG C~70 DEG C) liquid extract.
A kind of 8. preparation method for the Chinese medicine composition for treating prostatic disorders according to claim 4, it is characterised in that institute It is 60~80 DEG C to state the temperature being dried under reduced pressure.
A kind of 9. preparation method for the Chinese medicine composition for treating prostatic disorders according to claim 4, it is characterised in that institute It is 800~1000 mesh to state micronization and be crushed to fineness.
A kind of 10. preparation method for the Chinese medicine composition for treating prostatic disorders according to claim 4, it is characterised in that： Finished product preparation made of described is tablet, pulvis, capsule or granule.