CN107822967A - A kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy - Google Patents
A kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy Download PDFInfo
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- CN107822967A CN107822967A CN201711155179.8A CN201711155179A CN107822967A CN 107822967 A CN107822967 A CN 107822967A CN 201711155179 A CN201711155179 A CN 201711155179A CN 107822967 A CN107822967 A CN 107822967A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
- A61K8/8176—Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention belongs to skin care applications, particularly relate to a kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy and preparation method and application.The gel preparation includes component A, B component, component C, D components and component E, component A includes water, glycerine, Chondrus crispus extract, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans, B component includes parahydroxyacet-ophenone, hexylene glycol, pentanediol, component C includes EDETATE SODIUM, aluminum glycinate and tartaric acid, D components include CI 19140, CI 15985, mica, titanium dioxide, iron oxide and tin ash, component E includes water, Black Ganoderma extract, hamamelis extract, acetyl group hexapeptide 8, palmityl tripeptides 5 and pungent glycol, the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy of the present invention can significantly help skin to improve anti-wrinkle, it is anti-ageing and other effects.
Description
Technical field
The invention belongs to skin care applications, particularly relate to a kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy
And preparation method and application.
Background technology
Wrinkle refers to that skin is influenceed by external environment, forms free free radical, and free radical destroys normal cell membrane tissue
Interior collagen, active material, oxidative cell and the small microgroove, the wrinkle that are formed.It is common such as pouch, senile skin of upper eyelid
Sagging, augnathus etc..Eyelid position：It is more common at upper eyelid outer 1/3., can be with eyelid and skin in upper eyelid due to gravity relationship
The gradual relaxation of orbicularis and skin sagging occurs, lower eyelid sometimes also can be gradually sagging, at the same can also due to Orbital septum fat from every
Film hernia goes out and formed " upper eyelid ".Face：Such wrinkle is occurred in face bottom, because the fat of fat pad under eyelid is reduced, eyelid cheek
Portion's skin becomes loose, so as to wrinkle occur.Jaw portion：Such wrinkle is occurred in jaw bottom, because subcutaneous fat is reduced, lower jaw
Cutis laxa forms " hang down jaw ".Neck：The orthostatic wrinkle of neck occurred after the middle age, due to the gradual atrophy of hypodermis
Reduce, cutis laxa, intensification added plus Action of Gravity Field, especially in throat portion, often can in the neck of both sides platysma edge shape
The wrinkle of skin sagging into two.
With the development of the society, expanding economy.The pressure of people is increasing.It is often depressed, it is irritable, it is lonely
It is out-of-the-way, distress, anxiety, overcautious expression usually are shown in face, this expression affects mimetic muscle and produced vertical or horizontal
Wrinkle, make one to engender aging phenomenon.People often have not enough sleep, and can be damaged the regulatory function of skin, cause appearance thin and pallid
It is worried, easy aging corrugation.The excessive exposure due to work, can cause skin injury, make the skin of face, neck, hand
Skin is dried, is thinning, following the string, and makes elastic fibers and gtelatinous fibre loses normal function, and skin gradually fluffs corrugation.If
Nutritional condition of body is good, and the nutrition supply of skin is sufficient, and hypodermis is plentiful, the evening that wrinkle occurs as soon as；As nutrition condition is bad,
Cause integumentary musculature histotrophic nutrition bad, cause pachylosis and relaxation, easily produce main wrinkle.People are in order to pursue beauty, greatly
Amount uses cosmetics, and the quality of skin can be destroyed using unsuitable cosmetics, and it is thin that excessive face powder also can occur face
Close rugula.Meanwhile long-term excessively smoking, the aging of skin can be accelerated, so as to produce wrinkle too early by drinking, make one to present a weathered appearance
It is wan and sallow.
Since smoothing wrinkle technology develops, there is the rhytidectomy formula of three generations's standard, the method for these wrinkle reductions is present
Operation wound is big, the shortcomings that complex operation.It is specific as follows：Cicatricial baldness, facial asymmetry, the damage of facial nerve, sensation barrier
Hinder, expression it is unnatural, also the possibility that many complication occurs such as form just like hemotoncus, infection, facial scar after rhytidectomy.
At present, in order to reach desalination skin fine wrinkles, color spot and acne scar, skin permanent damp etc. is kept to improve skin quality
Effect, be generally incorporated in the prior art in cosmetics abundant skin nutrition product or add with covering power, refractive index is high and
The high pigment of the tinting strength, tinting power of microparticle, such as soybean lecithin, vitamin, collagen, titanium dioxide, red lead, organic pigment
Deng.Abundant nutritional ingredient makes the skin of the skin quality such as dryness, neutrality, oiliness more moisten, and the pigment of strong covering power is directed to skin
Present on fine wrinkles, color spot, acne scar etc. covered.But these nutritional ingredients only have part by percutaneous absorption, and it is exhausted
The problem of largely simply remaining in skin surface, therefore causing to waste and remain.Importantly, some moisturizing ingredients are excessively
Greasy, skin can not fully absorb, and form grease and be piled up in pore, the problem of causing clogging of pores；And add strong hide
The cosmetics of the pigment of lid power, it is effective the shortcomings that on adjustment color spot, freckle, the tone such as acne scar, and it is to fine wrinkles, acne scar
Improvement Deng obvious modal shortcoming is but less effective, or even can make fine wrinkles more prominent on the contrary sometimes.
So crease-resistant still need to pick up from source, the activity of oxygen radical is contained using antioxidant content, slows down or reduces oxygen
Destruction of the free radical to epidermal cell, the moisture and grease of skin are supplemented in combination with the composition of some conventional moisturizings,
Skin is set to reach a kind of full state.Thus, there is provided a kind of new gel preparation, which is added in skin care item, reaches prevention skin
Skin aging, better anti-oxidant crease-resistant effect, it is that current cosmetic field needs one of problem to make a breakthrough badly.
The content of the invention
To overcome disadvantages mentioned above, present invention aims at provide a kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy and system
Preparation Method and application.
The technical solution adopted by the present invention is：The long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, it is characterised in that：Including A
Component, B component, component C, D components and component E, the component A include water, glycerine, Chondrus crispus extract, polyacrylic acid
Sodium, polyvinylpyrrolidone, cellulose gum and xanthans, the B component include parahydroxyacet-ophenone, hexylene glycol, pentanediol, institute
Stating component C includes EDETATE SODIUM, aluminum glycinate and tartaric acid, and the D components include CI 19140, CI 15985, mica, dioxy
Change titanium, iron oxide and tin ash, the component E includes water, Black Ganoderma extract, hamamelis extract, acetyl group six
Peptide -8, palmityl tripeptides -5 and pungent glycol；The percentage by weight of feed components is component A：Water 38-50%, glycerine 5-
20%th, Chondrus crispus extract 1-5%, Sodium Polyacrylate 1-3%, polyvinylpyrrolidone 1-3%, cellulose gum 1-3%,
Xanthans 1-3%；B component：Parahydroxyacet-ophenone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C 0.3-
5%, D component 1.2-3%, component E：18.5-45%.
Preferably, the percentage by weight of feed components is component A：Water 44-50%, glycerine 5-10%, Chondrus crispus
Extract 1-5%, Sodium Polyacrylate 1-3%, polyvinylpyrrolidone 1-3%, cellulose gum 1-3%, xanthans 1-3%；B groups
Point：Parahydroxyacet-ophenone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C 0.3-5%；D components 1.2-
3%；Component E：18.5-30.01%.
Preferably, the percentage by weight of feed components is component A：Water 38-50%, glycerine 5-20%, Chondrus crispus
Extract 1-5%, Sodium Polyacrylate 1-3%, polyvinylpyrrolidone 1-3%, cellulose gum 1-3%, xanthans 1-3%；B groups
Point：Parahydroxyacet-ophenone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C includes EDETATE SODIUM 0.1-
1%th, aluminum glycinate 0.1-2%, tartaric acid 0.1-2%；D components 1.2-3%；Component E：18.5-45%.
Preferably, the percentage by weight of feed components is component A：Water 38-50%, glycerine 5-20%, Chondrus crispus
Extract 1-5%, Sodium Polyacrylate 1-3%, polyvinylpyrrolidone 1-3%, cellulose gum 1-3%, xanthans 1-3%；B groups
Point：Parahydroxyacet-ophenone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C includes EDETATE SODIUM 0.1-
1%th, aluminum glycinate 0.1-2%, tartaric acid 0.1-2%；D components include 15985 0.1- of 0.1-0.3%, CI of CI 19140
0.3%th, mica 0.2-0.6%, titanium dioxide 0.2-0.6%, iron oxide 0.3-0.6%, tin ash 0.3-0.6%；E groups
Point：18.5-45%.
Preferably, the percentage by weight of feed components is component A：Water 38-50%, glycerine 5-20%, Chondrus crispus
Extract 1-5%, Sodium Polyacrylate 1-3%, polyvinylpyrrolidone 1-3%, cellulose gum 1-3%, xanthans 1-3%；B groups
Point：Parahydroxyacet-ophenone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C includes EDETATE SODIUM 0.1-
1%th, aluminum glycinate 0.1-2%, tartaric acid 0.1-2%；D components include 15985 0.1- of 0.1-0.3%, CI of CI 19140
0.3%th, mica 0.2-0.6%, titanium dioxide 0.2-0.6%, iron oxide 0.3-0.6%, tin ash 0.3-0.6%；Component E
Including water 10.25-22.7%, Black Ganoderma extract 1-5%, hamamelis extract 1-5%, Argireline 1-
2%th, the 1-2% of palmityl tripeptides -5 and pungent glycol 0.1-0.15%.
Further, the extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, with 95% ethanol or fourth
Glycol derect seething, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean ripple angle is taken to pitch
Dish adds the water immersion 24-48h of 10-20 times of its weight, then carries out steam distillation, distillate is collected, under the conditions of -5 DEG C
Avoid light place 8-12h, filtering is taken out, collect filter cake, obtain Chondrus crispus extract.
Present invention also offers a kind of preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, including following step
Suddenly：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 80-85 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
Present invention also offers a kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy to prepare the cosmetics of skin nursing
Application in field.
Black Ganoderma extract：Contain ganoderma lucidum triterpene, polysaccharide, protein, amino acid, adenine, steroid saponin, micro member
Plain active ingredient, have the significant SOD that intends active, free radical caused by body can be significantly removed, so as to prevent free radical to machine
The damage of body, it is therefore prevented that the peroxidating of fat body, protect cell, delayed cell ageing, it is comprehensive play anti-oxidant, anti-aging,
Antibacterial effect.
Hamamelis extract：It is a variety of as Ellagtannin and Hamamlitannin can adjust skin to include tannin matter
Fat secretion, witch hazel Hydrolyzed Protein and Milk Protein；Promote lymph blood circulation, specially overcome morning eye bladder and livid ring around eye；Have
Effect that is calm, pacifying, to being cracked, tanning severely, acne have improvement；The power of regeneration at skin night can effectively be helped；Remove
Pouch, loosen and relax and have very excellent effect to the skin of what oily skin or allergy；Releive, restrain, antibacterial
Effect, because have convergence oil-control, sterilization significant curative effect；It is comprehensive play anti-oxidant, enhancing skin cell metabolism, it is anti-ageing,
Anti-inflammatory, releive, restrain and the effect of moisturizing.
Position that Argireline is concentrated particularly suitable for expression muscle (around eyes, forehead, face etc.) it is crease-resistant
Maintenance, reduce the depth of wrinkle.Mechanism：Contraction of muscle forms wrinkle, and contraction of muscle is because have received the letter of neurotransmitter
Number causing, neurotransmitter comes from the secretion of vesica, and acetyl hexapeptide -8 prevents vesica from effectively discharging neurotransmitter, so as to
Contraction of muscle is reduced, reaches the purpose for mitigating wrinkle, different from the anesthesia mechanism of BOTOX, it is allowed to which muscle naturally moves
And expression, other side effects are not produced yet.
Chondrus crispus extract：With toxin expelling, deep layer cleaning, aging cutin, Firm are removed, moisten and desalinates wrinkle etc.
Effect, become careful glossy immediately using rear skin.
Drug Percutaneous Absorption process includes release, penetrates and be absorbed into blood circulation three phases.Release means medicine
Spin off and be diffused on skin or mucomembranous surface from matrix；Penetrate mean medicine by epidermis enter corium, subcutaneous group
Knit, mainly organize effect to local；Absorption mean medicine by after skin microcirculation or mucosal contact by blood vessel or lymph
Pipe enters body circulation and produces general action.The small medicine of its middle-molecular-weihydroxyethyl, can spread into cuticula, and diffusion velocity is more inward
It is bigger；The larger medicine of molecular weight is then based on pore and sweat gland approach.After balance is reached, highly polar medicine mainly with
Water of histone hydration etc. is diffused for medium；The low medicine of polarity then passes through fat-soluble Medium Diffusion.Gel has
Good bioadhesive, skin persistently can be acted on, be advantageous to the release and absorption of the active ingredient of medicine, again will not
Easy cleaning, patient be not very easy to use as the very big ointment of some viscosity.
The present invention is beneficial to be had technical effect that：The long-acting anti-wrinkle cosmetic gel preparation of dark fund energy of the present invention is by component A：
Water, glycerine, Chondrus crispus extract, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans, B component：It is right
Hydroxy acetophenone, hexylene glycol, pentanediol, component C：EDETATE SODIUM, aluminum glycinate and tartaric acid, D components：CI 19140、CI
15985th, mica, titanium dioxide, iron oxide and tin ash, component E：Water, Black Ganoderma extract, hamamelis extract,
Gel is made in Argireline, palmityl tripeptides -5 and pungent glycol composition, and gel slow-releasing system acts on skin epidermis
And corium, long action time, sustained release can make more active matters penetrate into skin, gel has sandwich construction, can include more
Active principle, functional component be combined with each other, and can significantly help skin to improve anti-wrinkle, anti-ageing and other effects, and also have makes flesh in addition
Skin improves water humidity, recovers the multi-efficiencies such as elasticity, regeneration, activation, exquisiteness, whitening, antioxygen.
Embodiment
The content that the present invention is furture elucidated with reference to embodiments, but the present invention is not restricted to the model of following examples
Enclose.
Embodiment 1
The long-acting anti-wrinkle cosmetic gel preparation of a kind of dark fund energy provided by the invention, including component A, B component, component C, D
Component and component E, the percentage by weight of feed components are component A：Water 50%, glycerine 20%, Chondrus crispus extract
1%th, Sodium Polyacrylate 1%, polyvinylpyrrolidone 3%, cellulose gum 1%, xanthans 1%；B component：Parahydroxyacet-ophenone
0.5%th, hexylene glycol 0.5%, pentanediol 2%；Component C：EDETATE SODIUM 0.1%, aluminum glycinate 0.1%, tartaric acid 0.1%；D groups
Point：CI 19,140 0.1%, CI 15,985 0.1%, mica 0.2%, titanium dioxide 0.2%, iron oxide 0.3%, tin ash
0.3%；Component E：Water 10.25%, Black Ganoderma extract 1%, hamamelis extract 1%, Argireline 1%, palm fibre
Palmitic acid acyl tripeptides -5 1%, pungent glycol 0.1%.
The preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, is comprised the following steps：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 80 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
The extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, it is direct with 95% ethanol or butanediol
Extraction, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean Chondrus crispus is taken to add it
The water immersion 36h that 15 times of weight, then carries out steam distillation, collects distillate, the avoid light place 10h under the conditions of -5 DEG C, take
Go out filtering, collect filter cake, obtain Chondrus crispus extract.
Embodiment 2
The long-acting anti-wrinkle cosmetic gel preparation of a kind of dark fund energy provided by the invention, including component A, B component, component C, D
Component and component E, the percentage by weight of feed components are component A：Water 40.69%, glycerine 5%, Chondrus crispus extract
2%th, Sodium Polyacrylate 2%, polyvinylpyrrolidone 1%, cellulose gum 3%, xanthans 3%；B component：Parahydroxyacet-ophenone
0.5%th, hexylene glycol 0.5%, pentanediol 3%；Component C：EDETATE SODIUM 0.4%, aluminum glycinate 1%, tartaric acid 0.2%；D groups
Point：CI 19,140 0.3%, CI 159850.1%, mica 0.3%, titanium dioxide 0.2%, iron oxide 0.5%, tin ash
0.5%；Component E：Water 22.7%, Black Ganoderma extract 2%, hamamelis extract 2%, Argireline 2%, palm fibre
Palmitic acid acyl tripeptides -5 2%, pungent glycol 0.15%.
The preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, is comprised the following steps：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 82 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
The extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, it is direct with 95% ethanol or butanediol
Extraction, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean Chondrus crispus is taken to add it
The water immersion 36h that 15 times of weight, then carries out steam distillation, collects distillate, the avoid light place 10h under the conditions of -5 DEG C, take
Go out filtering, collect filter cake, obtain Chondrus crispus extract.
Embodiment 3
The long-acting anti-wrinkle cosmetic gel preparation of a kind of dark fund energy provided by the invention, including component A, B component, component C, D
Component and component E, the percentage by weight of feed components are component A：Water 42%, glycerine 12.5%, Chondrus crispus extract
1.5%th, Sodium Polyacrylate 1%, polyvinylpyrrolidone 2%, cellulose gum 2%, xanthans 2%；B component：Para hydroxybenzene second
Ketone 0.6%, hexylene glycol 0.6%, pentanediol 3%；Component C：EDETATE SODIUM 0.5%, aluminum glycinate 0.5%, tartaric acid 1%；D groups
Point：CI 19,140 0.3%, CI 15,985 0.3%, mica 0.6%, titanium dioxide 0.6%, iron oxide 0.6%, tin ash
0.6%；Component E：Water 14.47%, Black Ganoderma extract 2%, hamamelis extract 2%, Argireline 1%, palm fibre
Palmitic acid acyl tripeptides -5 2%, pungent glycol 0.1%.
The preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, is comprised the following steps：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 83 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
The extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, it is direct with 95% ethanol or butanediol
Extraction, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean Chondrus crispus is taken to add it
The water immersion 36h that 15 times of weight, then carries out steam distillation, collects distillate, the avoid light place 10h under the conditions of -5 DEG C, take
Go out filtering, collect filter cake, obtain Chondrus crispus extract.
Embodiment 4
The long-acting anti-wrinkle cosmetic gel preparation of a kind of dark fund energy provided by the invention, including component A, B component, component C, D
Component and component E, the percentage by weight of feed components are component A：Water 38%, glycerine 10%, Chondrus crispus extract
5%th, Sodium Polyacrylate 3%, polyvinylpyrrolidone 1%, cellulose gum 1%, xanthans 1.5%；B component：Para hydroxybenzene second
Ketone 0.55%, hexylene glycol 0.55%, pentanediol 2.5%；Component C：EDETATE SODIUM 0.8%, aluminum glycinate 1.5%, tartaric acid
2%；D components：CI 19,140 0.1%, CI15985 0.1%, mica 0.5%, titanium dioxide 0.5%, iron oxide 0.4%, two
Tin oxide 0.4%；Component E：Water 17.33%, Black Ganoderma extract 3%, hamamelis extract 3%, Argireline
2%th, palmityl tripeptides -5 1%, pungent glycol 0.1%.
The preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, is comprised the following steps：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 84 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
The extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, it is direct with 95% ethanol or butanediol
Extraction, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean Chondrus crispus is taken to add it
The water immersion 36h that 15 times of weight, then carries out steam distillation, collects distillate, the avoid light place 10h under the conditions of -5 DEG C, take
Go out filtering, collect filter cake, obtain Chondrus crispus extract.
Embodiment 5
The long-acting anti-wrinkle cosmetic gel preparation of a kind of dark fund energy provided by the invention, including component A, B component, component C, D
Component and component E, the percentage by weight of feed components are component A：Water 44%, glycerine 10%, Chondrus crispus extract
1%th, Sodium Polyacrylate 2%, polyvinylpyrrolidone 3%, cellulose gum 1%, xanthans 1%；B component：Parahydroxyacet-ophenone
0.6%th, hexylene glycol 0.6%, pentanediol 2%；Component C：EDETATE SODIUM 1%, aluminum glycinate 1.2%, tartaric acid 0.1%；D groups
Point：CI 19,140 0.2%, CI 15,985 0.2%, mica 0.3%, titanium dioxide 0.4%, iron oxide 0.5%, tin ash
0.5%；Component E：Water 16.13, Black Ganoderma extract 3%, hamamelis extract 3%, Argireline 2%, palm
Acyl tripeptides -5 1%, pungent glycol 0.1%.
The preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, is comprised the following steps：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 85 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
The extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, it is direct with 95% ethanol or butanediol
Extraction, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean Chondrus crispus is taken to add it
The water immersion 24h that 10 times of weight, then carries out steam distillation, collects distillate, the avoid light place 8h under the conditions of -5 DEG C, take out
Filtering, filter cake is collected, obtains Chondrus crispus extract.
Embodiment 6
The long-acting anti-wrinkle cosmetic gel preparation of a kind of dark fund energy provided by the invention, including component A, B component, component C, D
Component and component E, the percentage by weight of feed components are component A：Component A：Water 40%, glycerine 8%, Chondrus crispus carry
Take thing 3%, Sodium Polyacrylate 1%, polyvinylpyrrolidone 3%, cellulose gum 2%, xanthans 2%；B component：Para hydroxybenzene
Ethyl ketone 0.6%, hexylene glycol 0.6%, pentanediol 3%；Component C：EDETATE SODIUM 1%, aluminum glycinate 2%, tartaric acid 2%；D groups
Point：CI 19,140 0.2%, CI 159850.2%, mica 0.4%, titanium dioxide 0.4%, iron oxide 0.4%, tin ash
0.3%；Component E：Water 10.7%, Black Ganoderma extract 5%, hamamelis extract 5%, Argireline 1%, palm fibre
Palmitic acid acyl tripeptides -5 1%, pungent glycol 0.1%.
The preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, is comprised the following steps：
(1) each raw material is weighed according to the percentage by weight of feed components, then extracts Chondrus crispus in component A
Thing, Sodium Polyacrylate, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；
(2) mixed liquor that step (1) obtains is added in component B, is then added component A reclaimed waters, is stirred, and heat
It is standby after colloid is completely dissolved to 85 DEG C；
(3) component C is added in the mixed liquor obtained to step (2), is stirred, it is standby；
(4) after the mixeding liquid temperature that step (3) obtains drops to 70 DEG C, component D is added, is stirred, it is standby；
(5) component E is added in the mixed liquor obtained to step (4), hot filling is cooled to room into container after stirring
Temperature, obtain finished product.
The extraction process of Chondrus crispus extract：Clean Chondrus crispus is taken, it is direct with 95% ethanol or butanediol
Extraction, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or clean Chondrus crispus is taken to add it
The water immersion 48h that 20 times of weight, then carries out steam distillation, collects distillate, the avoid light place 12h under the conditions of -5 DEG C, take
Go out filtering, collect filter cake, obtain Chondrus crispus extract.
Embodiment 7
Volunteer 70 is selected, selection standard is to have certain face/eye to have fine wrinkles phenomenon.Volunteer is random
It is divided into 7 groups, wherein 6 groups are distinguished the side cheek in the left cheek and right cheek of every volunteer at random, left eye angle and right eye
Side canthus in angle uses the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy of the present invention, as experimental group；Other 1 group of volunteer
The long-acting anti-wrinkle cosmetic gel preparation canthus of dark fund energy of the present invention or cheek is not used as a control group.Wherein, the 1st group of volunteer
Using the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy obtained by embodiment 1, the 2nd group of volunteer is used obtained by embodiment 2
The long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, the 3rd group of volunteer be long-acting crease-resistant using the dark fund energy obtained by embodiment 3
Beauty-care gel preparation, the 4th group of volunteer is using the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy obtained by embodiment 4, the 5th group
Volunteer uses embodiment 6 using the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy obtained by embodiment 5, the 6th group of volunteer
The long-acting anti-wrinkle cosmetic gel preparation of obtained dark fund energy.
Volunteer person respectively applies the once long-acting anti-wrinkle cosmetic gel preparation of dark fund energy of the present invention, service life sooner or later in daily
For 4 weeks, other cosmetics must not be used within test period.Then, it is black using face wrinkles' imager, the comparative analysis present invention
The golden long-acting anti-wrinkle cosmetic gel preparation of energy improves situation to volunteer's wrinkle, as a result as shown in table 1：
After testing, compared with control group, after test specimen is smeared, experimental group wrinkle roughness, wrinkle depth and wrinkle
Line volume shoals, and improves significantly.The long-acting anti-wrinkle cosmetic of dark fund energy of the present invention it can be seen from above result of the test
Gel preparation can prevent and improve the aging of skin.
Embodiment 8
Different experiments group and the heterogeneity proportioning effect of control group are detected, chooses the people of volunteer 120, selection standard is to have
The relaxation of certain face/eye part skin or face/eye have a fine wrinkles phenomenon, pachylosis performance, the age at 35~55 years old,
Men and women is unlimited, and 120 people are randomly divided into 6 groups, every group of 20 people respectively in the morning with above-mentioned case study on implementation is used after evening cleaning skin
In the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, during which all do not use other skin care item, continuous 8 week, whole process
For Blind Test.
Wherein, the 1st group of volunteer is using the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy obtained by embodiment 1, the 2nd group
Volunteer uses embodiment 3 using the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy obtained by embodiment 2, the 3rd group of volunteer
The long-acting anti-wrinkle cosmetic gel preparation of obtained dark fund energy, the 4th group of volunteer are grown using the dark fund energy obtained by embodiment 4
Anti-wrinkle cosmetic gel preparation is imitated, the 5th group of volunteer uses the long-acting anti-wrinkle cosmetic gel system of dark fund energy obtained by embodiment 5
Agent, the 6th group of volunteer use the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy obtained by embodiment 6.
Before use and using facial imaging is carried out respectively after 8 weeks, using VISIA face-image analysis systems to subject
Face is taken pictures in (front, 45 ° of directions of left and right side).Wrinkle score value and texture score value are extracted, is averaged, wrinkle score value becomes
Rate (B%)=(using the rear preceding wrinkle score value of wrinkle score value-use)/uses preceding wrinkle score value × 100%, as a result such as the institute of table 2
Show：
Wrinkle rate of change before and after the use of table 2
After testing, compared with control group, after test specimen is smeared, experimental group can significantly reduce wrinkle, anti-wrinkle effect
Fruit is obvious.
The technical concepts and features of embodiment of above only to illustrate the invention, its object is to allow be familiar with technique
People understands present disclosure and is carried out, and it is not intended to limit the scope of the present invention, all according to spirit of the invention
The equivalent change or modification that essence is done, it should all cover within the scope of the present invention.
Claims (8)
- A kind of 1. long-acting anti-wrinkle cosmetic gel preparation of dark fund energy, it is characterised in that：Including component A, B component, component C, D components And component E, the component A include water, glycerine, Chondrus crispus extract, Sodium Polyacrylate, polyvinylpyrrolidone, fiber Plain glue and xanthans, the B component include parahydroxyacet-ophenone, hexylene glycol, pentanediol, the component C include EDTA disodiums, Aluminum glycinate and tartaric acid, the D components include CI 19140, CI 15985, mica, titanium dioxide, iron oxide and titanium dioxide Tin, the component E include water, Black Ganoderma extract, hamamelis extract, Argireline, palmityl tripeptides -5 and Pungent glycol；The percentage by weight of feed components is component A：Water 38-50%, glycerine 5-20%, Chondrus crispus extract 1- 5%th, Sodium Polyacrylate 1-3%, polyvinylpyrrolidone 1-3%, cellulose gum 1-3%, xanthans 1-3%；B component：Para hydroxybenzene second Ketone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C 0.3-5%；D components 1.2-3%；Component E：18.5-45%.
- 2. the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy according to claim 1, it is characterised in that：Feed components Percentage by weight is component A：Water 44-50%, glycerine 5-10%, Chondrus crispus extract 1-5%, Sodium Polyacrylate 1-3%, Polyvinylpyrrolidone 1-3%, cellulose gum 1-3%, xanthans 1-3%；B component：Parahydroxyacet-ophenone 0.5-0.6%, hexylene glycol 0.5-0.6%, pentanediol 2-3%；Component C 0.3-5%；D components 1.2-3%；Component E：18.5-30.01%.
- 3. the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy according to claim 1, it is characterised in that：The component C Percentage by weight is that component C includes EDTA disodiums 0.1-1%, aluminum glycinate 0.1-2%, tartaric acid 0.1-2%.
- 4. the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy according to claim 3, it is characterised in that：The D components Percentage by weight is, D components include 15985 0.1-0.3% of 0.1-0.3%, CI of CI 19140, mica 0.2-0.6%, titanium dioxide Titanium 0.2-0.6%, iron oxide 0.3-0.6%, tin ash 0.3-0.6%.
- 5. the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy according to claim 4, it is characterised in that：The component E Percentage by weight is that component E includes water 10.25-22.7%, Black Ganoderma extract 1-5%, hamamelis extract 1-5%, second The 1-2% of acyl group hexapeptide -8, the 1-2% of palmityl tripeptides -5 and pungent glycol 0.1-0.15%.
- 6. a kind of preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy described in claim 1-5 any one, its It is characterised by：The extraction process of the Chondrus crispus extract：Clean Chondrus crispus is taken, with 95% ethanol or fourth two Alcohol derect seething, is then condensed into medicinal extract by extract, obtains Chondrus crispus extract；Or take clean Chondrus crispus The water immersion 24-48h of 10-20 times of its weight is added, steam distillation is then carried out, collects distillate, kept away under the conditions of -5 DEG C Light places 8-12h, takes out filtering, collects filter cake, obtains Chondrus crispus extract.
- 7. the preparation method of the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy according to claim 1-5 any one, its It is characterised by：Comprise the following steps：（1）Percentage by weight according to feed components weighs each raw material, then by Chondrus crispus extract in component A, poly- PAA, polyvinylpyrrolidone, cellulose gum and xanthans be added in glycerine it is pre-dispersed uniformly, it is standby；（2）Step（1）Obtained mixed liquor is added in component B, is then added component A reclaimed waters, is stirred, and be heated to It is 80-85 DEG C, standby after colloid is completely dissolved；（3）To step（2）Component C is added in obtained mixed liquor, is stirred, it is standby；（4）Treat step（3）After obtained mixeding liquid temperature drops to 70 DEG C, component D is added, is stirred, it is standby；（5）To step（4）Component E is added in obtained mixed liquor, hot filling is cooled to room temperature into container after stirring, Obtain finished product.
- 8. the long-acting anti-wrinkle cosmetic gel preparation of dark fund energy described in a kind of claim 1-5 any one is preparing skin nursing Cosmetic field in application.
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