CN115813775A - Hydrogel system process - Google Patents
Hydrogel system process Download PDFInfo
- Publication number
- CN115813775A CN115813775A CN202111092730.5A CN202111092730A CN115813775A CN 115813775 A CN115813775 A CN 115813775A CN 202111092730 A CN202111092730 A CN 202111092730A CN 115813775 A CN115813775 A CN 115813775A
- Authority
- CN
- China
- Prior art keywords
- raw materials
- qualified
- materials
- filling
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000017 hydrogel Substances 0.000 title claims abstract description 23
- 230000026676 system process Effects 0.000 title claims abstract description 15
- 239000002994 raw material Substances 0.000 claims abstract description 26
- 239000000463 material Substances 0.000 claims abstract description 17
- 238000004519 manufacturing process Methods 0.000 claims abstract description 13
- 238000011049 filling Methods 0.000 claims abstract description 11
- 239000011248 coating agent Substances 0.000 claims abstract description 9
- 238000000576 coating method Methods 0.000 claims abstract description 9
- 239000005022 packaging material Substances 0.000 claims abstract description 9
- 238000003860 storage Methods 0.000 claims abstract description 9
- 238000007599 discharging Methods 0.000 claims abstract description 8
- 238000007689 inspection Methods 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims abstract description 5
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000000084 colloidal system Substances 0.000 claims abstract description 4
- 239000002131 composite material Substances 0.000 claims abstract description 4
- 238000004080 punching Methods 0.000 claims abstract description 4
- 238000005070 sampling Methods 0.000 claims abstract description 4
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 6
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 3
- 108010022355 Fibroins Proteins 0.000 claims description 3
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 claims description 3
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims description 3
- BWZOPYPOZJBVLQ-UHFFFAOYSA-K aluminium glycinate Chemical compound O[Al+]O.NCC([O-])=O BWZOPYPOZJBVLQ-UHFFFAOYSA-K 0.000 claims description 3
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 3
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 3
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 3
- 229940032094 squalane Drugs 0.000 claims description 3
- 235000002906 tartaric acid Nutrition 0.000 claims description 3
- 239000011975 tartaric acid Substances 0.000 claims description 3
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 2
- XGDPKUKRQHHZTH-UHFFFAOYSA-N Methyl 2,5-dihydroxybenzoate Chemical compound COC(=O)C1=CC(O)=CC=C1O XGDPKUKRQHHZTH-UHFFFAOYSA-N 0.000 claims description 2
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 2
- 229940107131 ginseng root Drugs 0.000 claims description 2
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 2
- 235000019477 peppermint oil Nutrition 0.000 claims description 2
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 238000002156 mixing Methods 0.000 abstract description 7
- 238000003756 stirring Methods 0.000 abstract description 4
- 230000001580 bacterial effect Effects 0.000 abstract description 3
- 238000009395 breeding Methods 0.000 abstract description 3
- 230000001488 breeding effect Effects 0.000 abstract description 3
- 230000008859 change Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 9
- 230000008569 process Effects 0.000 description 7
- 239000000126 substance Substances 0.000 description 6
- 230000001804 emulsifying effect Effects 0.000 description 4
- 230000001815 facial effect Effects 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000002313 adhesive film Substances 0.000 description 3
- 239000002537 cosmetic Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 2
- 240000004371 Panax ginseng Species 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 125000001165 hydrophobic group Chemical group 0.000 description 2
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 description 1
- 235000006679 Mentha X verticillata Nutrition 0.000 description 1
- 244000245214 Mentha canadensis Species 0.000 description 1
- 235000001878 Mentha haplocalyx Nutrition 0.000 description 1
- 235000002899 Mentha suaveolens Nutrition 0.000 description 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 1
- 235000002789 Panax ginseng Nutrition 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 238000010382 chemical cross-linking Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- BRIAJMLKQGLZGX-UHFFFAOYSA-N dihydroxymethyl benzoate Chemical compound OC(O)OC(=O)C1=CC=CC=C1 BRIAJMLKQGLZGX-UHFFFAOYSA-N 0.000 description 1
- 229960001484 edetic acid Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 239000011265 semifinished product Substances 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Images
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a hydrogel system process, which has ideal biocompatibility and is characterized in that: firstly, respectively mixing and stirring A, B groups of raw materials until the raw materials are completely dissolved in a vacuum state at the temperature of 30 ℃; then, under the vacuum state and at the temperature of 30 ℃, mixing the A, B groups of raw materials which are respectively mixed together, and stirring for 30 minutes until the raw materials are completely mixed; discharging the materials into a storage barrel, and standing for 12 hours in a standing room; sampling and sending to a laboratory for inspection, and discharging qualified materials; the qualified materials are coated on a coating machine to be subjected to three-layer composite coating, so that the whole production process is smooth, sanitary and sterile, and bacterial breeding and product quality change caused by improper operation are avoided; placing the coated sheet in a standing room to cure the colloid for 24 hours, and then punching and forming according to a die; inspecting the packaging material, performing ozone disinfection treatment, and entering a production line for bagging after the packaging material is inspected to be qualified; filling through an aseptic automatic filling assembly line; after filling, the mixture is inspected to be qualified and accepted for storage.
Description
Technical Field
The invention relates to a cosmetic process, in particular to a hydrogel system process for processing a hydrogel adhesive film, which has the characteristics of safety, high quality, ideal biocompatibility, no sensitization, no stimulation, no toxic or side effect, stability, reliability, environmental protection, nature and health care, mature processing technology and perfect manufacturing and matching.
Background
The hydrogel is a high molecular network system, has soft property, can keep a certain shape, can absorb a large amount of water, introduces a part of hydrophobic groups and hydrophilic residues into the water-soluble high polymer with a reticular cross-linked structure, the hydrophilic residues are combined with water molecules, and the hydrophobic residues are cross-linked polymers which swell when meeting water. The problem that traditional application membrane exists has been solved in the research and development of current aquogel facial mask, still keeps the gel state after can absorbing the moisture that is equivalent to hundreds of times of self quality, has fine lock water nature, and the aquogel absorbs water after the swelling can be fine simulation human tissue, and compliance and viscoelasticity are better, can perfectly attach human skin surface. At present, the hydrogel prepared by a chemical crosslinking method has high speed, but the components have potential hazards; radiation crosslinking can cause the hydrogel to yellow in color; the hydrogel prepared by the freeze-thaw crosslinking method has the characteristics of high strength and no desquamation, but the hydrogel has the defects of rough skin contact feeling and low transparency, and particularly has poor biocompatibility.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a hydrogel system process, which effectively promotes the uniform mixing of different material solutions under the dissolving condition, particularly effectively solves the process problem of complete mixing of different material groups, and improves the technical content and stability of the process, thereby meeting the high-quality marketing requirement of cosmetics.
The technical problem of the invention is realized according to the following technical scheme: a hydrogel system process is characterized in that firstly, raw materials of A, B groups are respectively mixed and stirred until being completely dissolved under the vacuum state and the temperature is 30 ℃; then, under the vacuum state and at the temperature of 30 ℃, mixing the A, B groups of raw materials which are respectively mixed together, and stirring for 30 minutes until the raw materials are completely mixed; discharging the materials into a storage barrel, and standing for 12 hours in a standing room; sampling and sending to a laboratory for inspection, and discharging qualified materials; the qualified materials are coated on a coating machine to be subjected to three-layer composite coating, so that the whole production process is smooth, sanitary and sterile, and bacterial breeding and product quality change caused by improper operation are avoided; placing the coated sheet in a standing room to cure the colloid for 24 hours, and then punching and forming according to a die; inspecting the packaging material, performing ozone disinfection treatment, and entering a production line for bagging after the packaging material is inspected to be qualified; filling through an aseptic automatic filling assembly line; after filling, the mixture is inspected to be qualified and accepted for storage.
The invention provides a hydrogel system process which is characterized in that the A, B group raw materials comprise water, glycerol, sodium polyacrylate, tartaric acid, phenoxyethanol, methyl dihydroxybenzoate, aluminum glycinate, disodium EDTA (ethylene diamine tetraacetic acid), polyvinylpyrrolidone, sodium hyaluronate, squalane, silk fibroin, hydrolyzed pearl, acetyl hexapeptide-8, ginseng (Panax Ginseng) root extract and mint (Mentha Haplocalyx) oil.
The hydrogel system process has the following advantages: the preparation method has the characteristics of simple and mature process, reliable technology, ideal effect, softness, smoothness, transparent gloss, good ductility, toughness and good adhesiveness, particularly realizes the complete mixing of the A, B groups of raw materials which are respectively mixed under the vacuum state and the temperature of 30 ℃, improves the stability and reliability of the process, improves the commercial value, and has the characteristics of environmental protection, nature and health care.
Drawings
FIG. 1 is a schematic process flow block diagram of the hydrogel system process of the present invention.
Detailed Description
The invention relates to a hydrogel system process, wherein a processing material comprises A, B groups of raw materials, which comprise water, glycerol, sodium polyacrylate, tartaric acid, phenoxyethanol, dihydroxy methyl benzoate, aluminum glycinate, EDTA disodium, polyvinylpyrrolidone, sodium hyaluronate, squalane, silk fibroin, hydrolyzed pearl, acetyl hexapeptide-8, a ginseng root extract and peppermint oil.
When the invention is implemented specifically, the equipment adopts a homogenizing emulsifying pot, A, B groups of raw materials are respectively and sequentially heated through the homogenizing emulsifying pot, stirred until the raw materials are completely dissolved uniformly, when the raw materials are heated to 80-85 ℃, the homogenizing emulsifying pot is stirred for homogenization, vacuumized until the raw materials in the homogenizing emulsifying pot are in a negative pressure state, then the temperature is kept for 30 minutes, stirred, cooled and cooled to 30 ℃, namely, the raw materials in A, B groups are respectively mixed and stirred until the raw materials are completely dissolved when the temperature is 30 ℃ in a vacuum state; then, under the vacuum state and at the temperature of 30 ℃, mixing the A, B groups of raw materials which are respectively mixed together, and stirring for 30 minutes until the raw materials are completely mixed; discharging the materials into a storage barrel, and standing for 12 hours in a standing room; sampling and sending to a laboratory for inspection, and discharging qualified materials; the qualified materials are coated on a coating machine to be subjected to three-layer composite coating, so that the whole production process is smooth, sanitary and sterile, and bacterial breeding and product quality change caused by improper operation are avoided; placing the coated sheet in a standing room to cure the colloid for 24 hours, and then punching and forming according to a die; inspecting the packaging material, performing ozone disinfection treatment, putting the packaging material into a production line for bagging after the packaging material is inspected to be qualified, and performing aseptic automatic assembly line filling; after filling, the mixture is inspected to be qualified and accepted for storage. Reference is made to fig. 1.
In the specific implementation process, the hydrogel adhesive film is particularly suitable for hydrogel adhesive films with skin care functions, and through professional inspection, the raw materials do not contain safety risk substances, and no safety risk substances are generated or introduced in the production process. The formula of the invention adopts stable chemical properties of the raw materials, and the raw materials do not generate risk substances after being mixed according to the known chemical interaction; in the production process of the hydrogel system process, all equipment, tools and pipelines which contact raw and auxiliary materials and semi-finished products of cosmetics are made of non-toxic, harmless and anti-corrosion materials, the inner wall of the equipment is smooth and does not fall off, and the production equipment is periodically maintained, maintained and cleaned; the production equipment does not introduce safety risk substances. In summary, through the evaluation of the impurities brought in by the raw materials and generated in the production process of the hydrogel system process, the safety risk of using the product is not found, namely, the product cannot be harmful to the health of human bodies under normal, reasonable and foreseeable use conditions. When the facial mask is used specifically, the facial skin is cleaned firstly, then the facial mask is coated with toner, the microcrystalline protein patch mask prepared by the hydrogel system process is lightly pasted on the skin around the eyes, the position is adjusted, and the mask is not required to be cleaned after use. The storage condition is preferably dark and normal temperature storage.
Claims (2)
1. A hydrogel system process is characterized in that firstly, raw materials of A, B groups are respectively mixed and stirred to be completely dissolved under the vacuum state and the temperature is 30 ℃;
then, under the vacuum state, the temperature is 30 ℃, the A, B groups of raw materials which are respectively mixed are mixed together, and the mixture is stirred for 30 minutes until the raw materials are completely mixed;
discharging the materials into a storage barrel, and standing for 12 hours in a standing room;
sampling and sending to a laboratory for inspection, and discharging qualified materials;
coating the qualified material on a cloth coating machine to perform three-layer composite coating;
placing the coated sheet in a standing room to cure the colloid for 24 hours, and then punching and forming according to a die;
inspecting the packaging material, performing ozone disinfection treatment, and entering a production line for bagging after the packaging material is inspected to be qualified;
filling through an aseptic automatic filling assembly line;
after filling, the mixture is inspected to be qualified, accepted and warehoused.
2. The hydrogel system process as claimed in claim 1, wherein the A, B group of raw materials comprises water, glycerol, sodium polyacrylate, tartaric acid, phenoxyethanol, methyl dihydroxybenzoate, aluminum glycinate, disodium EDTA, polyvinylpyrrolidone, sodium hyaluronate, squalane, silk fibroin, hydrolyzed pearl, acetyl hexapeptide-8, ginseng root extract, and peppermint oil.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111092730.5A CN115813775A (en) | 2021-09-17 | 2021-09-17 | Hydrogel system process |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111092730.5A CN115813775A (en) | 2021-09-17 | 2021-09-17 | Hydrogel system process |
Publications (1)
Publication Number | Publication Date |
---|---|
CN115813775A true CN115813775A (en) | 2023-03-21 |
Family
ID=85515249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111092730.5A Pending CN115813775A (en) | 2021-09-17 | 2021-09-17 | Hydrogel system process |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN115813775A (en) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014032341A1 (en) * | 2012-08-27 | 2014-03-06 | 上海捷儿金保温制品有限公司 | Process for manufacturing hydrogel pad |
CN107822967A (en) * | 2017-11-20 | 2018-03-23 | 艾因特丽(苏州)生物科技有限公司 | A kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy |
CN109846752A (en) * | 2019-04-04 | 2019-06-07 | 邱美玲 | A kind of collagen water light is against age facial mask and preparation method thereof |
KR101983695B1 (en) * | 2018-12-19 | 2019-09-03 | 주식회사 메디셀 | Eye patch and manufacturing method the same using skin temperature-sensitized hydrogel |
KR20200116379A (en) * | 2019-04-01 | 2020-10-12 | 퓨어앤텍 주식회사 | Hydrogel mask pack and manufacturing method thereof |
CN113181071A (en) * | 2021-05-19 | 2021-07-30 | 张超 | Eye gel patch |
-
2021
- 2021-09-17 CN CN202111092730.5A patent/CN115813775A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014032341A1 (en) * | 2012-08-27 | 2014-03-06 | 上海捷儿金保温制品有限公司 | Process for manufacturing hydrogel pad |
CN107822967A (en) * | 2017-11-20 | 2018-03-23 | 艾因特丽(苏州)生物科技有限公司 | A kind of long-acting anti-wrinkle cosmetic gel preparation of dark fund energy |
KR101983695B1 (en) * | 2018-12-19 | 2019-09-03 | 주식회사 메디셀 | Eye patch and manufacturing method the same using skin temperature-sensitized hydrogel |
KR20200116379A (en) * | 2019-04-01 | 2020-10-12 | 퓨어앤텍 주식회사 | Hydrogel mask pack and manufacturing method thereof |
CN109846752A (en) * | 2019-04-04 | 2019-06-07 | 邱美玲 | A kind of collagen water light is against age facial mask and preparation method thereof |
CN113181071A (en) * | 2021-05-19 | 2021-07-30 | 张超 | Eye gel patch |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR101868183B1 (en) | Process of preparing a cross linked gel | |
CN108273122A (en) | A kind of recombined collagen hydrogel wound dressing and its preparation method and application | |
CN109876179A (en) | A kind of aerogel dressing and preparation method thereof | |
CN106029176A (en) | Silk potein fragment compositions and articles manufactured therefrom | |
CN107998437B (en) | Nano cross-linked sodium hyaluronate gel and preparation method and application thereof | |
CN110885455A (en) | Preparation and application of active oxygen response hydrogel | |
CN103755981A (en) | Hydrogel used as skin filling material and preparation method thereof | |
CN107200855A (en) | A kind of preparation method of polyvinyl alcohol hydrogel | |
CN112121032A (en) | Hydrogel patch for skin care and preparation method thereof | |
CN105125420A (en) | Drug gel system for relieving conventional skin problems and preparation method thereof | |
CN101612408A (en) | B ultrasonic couplant and preparation method | |
TWI387620B (en) | Method for producing cross-linked hyaluronic acid | |
CN115813775A (en) | Hydrogel system process | |
CN106620734B (en) | A kind of sterile medical supersonic coupled patch and preparation method thereof | |
CN110384647A (en) | A kind of hydrogen-rich water vegetarian noodles film and preparation method thereof | |
CN116549675A (en) | Non-irritating medical ultrasonic coupling agent and preparation method thereof | |
CN103446177B (en) | Cleansing solution for curing gynecological disease and preparation method thereof | |
CN110279887A (en) | A kind of multipurpose photon epoxy resin and preparation method thereof | |
CN102492033A (en) | Human-like collagen and human-like collagen composite sodium hyaluronate hydrogel | |
CN109846745A (en) | Sterile no added epidermis maintenance Essence of one kind and preparation method thereof | |
WO2022011849A1 (en) | Medical moisturizing eye patch and preparation method therefor | |
CN107582423A (en) | A kind of eye essence with moisture-keeping efficacy | |
JP2024502880A (en) | Biocompatible hydrogels containing hyaluronic acid, polyethylene glycol, and silicone-containing ingredients | |
CN112341664A (en) | Active agent, oxygen-free hyaluronic acid production method and product thereof | |
CN113069561A (en) | Medical ultrasonic coupling agent with disinfection function and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |