CN107802557A - A kind of hand frost - Google Patents

A kind of hand frost Download PDF

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Publication number
CN107802557A
CN107802557A CN201711317760.5A CN201711317760A CN107802557A CN 107802557 A CN107802557 A CN 107802557A CN 201711317760 A CN201711317760 A CN 201711317760A CN 107802557 A CN107802557 A CN 107802557A
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Prior art keywords
parts
extract
armeniaca mume
hand
hand frost
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CN201711317760.5A
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Chinese (zh)
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王露
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Individual
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Individual
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Priority to CN201711317760.5A priority Critical patent/CN107802557A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/81Preparation or application process involves irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides a kind of hand frost, belong to cosmetic technical field.The hand frost is made after 4~8 parts of antierythrite, 7~9 parts of aloe extract, 5~10 parts of SIMMONDSIA CHINENSIS SEED OIL, 3~7 parts of Miglyol 812N, 2~4 parts of lanolin alcohol APEO, 6~8 parts of armeniaca mume extract, 15~20 parts of glycerine, 5~7 parts of aqueous polyurethane, 1~3 part of vaseline, 2~4 parts of NMF and 3~6 parts of hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers are mixed.Hand frost provided by the invention not only has an excellent water conservation performance of keeping humidity, keeps skin wet, prevents the water loss in skin, is also sterilized with anti-inflammatory, the effect of clearing heat for detumescence, can significantly alleviate pernio symptom, be used in the winter time suitable for long pernio crowd.

Description

A kind of hand frost
Technical field
The present invention relates to cosmetic technical field, and in particular to a kind of hand frost.
Background technology
Hand lotion is the skincare product that most of women indispensabilities can be less.At present, on the market hand lotion species is various, is divided into Whitening hand cream, humidity-preserving type hand lotion, antifreeze hand lotion etc..The effect of the especially anti-freeze type hand lotion of use in winter is inadequate Good, for the crowd of long pernio, because pernio has itch fever phenomenon in the winter time, hand skin is more dried, these Hand lotion can not play good handguard effect to the crowd of long pernio well.Therefore it is badly in need of a kind of in the winter time to long pernio people Group has the hand frost of good water conservation handguard.
The content of the invention
The technical problems to be solved by the invention are, in order to overcome above shortcomings in the prior art, there is provided a kind of Hand frost.Hand frost provided by the invention not only has excellent water conservation performance of keeping humidity, keeps skin wet, prevents the moisture in skin It is lost in, is also sterilized with anti-inflammatory, the effect of clearing heat for detumescence, can significantly alleviates pernio symptom, suitable for long pernio crowd in the winter time Use.
Above-mentioned technical problem to be solved by this invention is achieved by the following technical programs:
A kind of hand frost, by weight, by 4~8 parts of antierythrite, 7~9 parts of aloe extract, 5~10 parts of lotus Lotus bar oil, 3~7 parts of Miglyol 812N, 2~4 parts of lanolin alcohol APEO, the extraction of 6~8 parts of armeniaca mume Thing, 15~20 parts of glycerine, 5~7 parts of aqueous polyurethane, 1~3 part of vaseline, 2~4 parts of NMF and 3~6 parts It is made after hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers mixing.
Preferably, the armeniaca mume extract is prepared in the following manner:By armeniaca mume in 10~15s -15~- It is quick-frozen to ice crystal shape at a temperature of 20 DEG C, added after crushed 20~30 mesh sieves in 95vt% ethanol solution, distill and go after stirring Except ethanol, the armeniaca mume extract is obtained.
Preferably, the mass ratio of the armeniaca mume and the ethanol solution is 1:6~9.
It is therein effective by the armeniaca mume extract that above-mentioned preparation method obtains compared to traditional armeniaca mume extract Composition is fixed when quick-frozen, and armeniaca mume petal becomes crisp, and active ingredient therein will not be destroyed, and more rich Collection, armeniaca mume extract made from this method have anti-inflammatory sterilization, the effect of clearing heat for detumescence, can effectively alleviate pernio itch Fever phenomenon.
Preferably, after the armeniaca mume after crushing is mixed with ethanol solution, zirconia ceramic microballoon is added, wherein, it is green The mass ratio of calyx plum and zirconia ceramic microballoon is 3~6:1, distillation removal ethanol after stirring.It is micro- to add zirconia ceramic Ball can break the cell membrane of armeniaca mume in stirring, make the effusion of active ingredient faster and more in armeniaca mume, improve green The action effect of calyx prunus mume extract.
Preferably, the aloe extract is prepared in the following manner:Aloe is mixed with 80vt% ethanol solution, Extracted in ultrasonic-microwave abstraction instrument, extract solution is post-processed and obtains aloe extract.
Preferably, the mass ratio of the aloe and the ethanol solution is 1:6~9.
Preferably, ultrasonic power is 60~70W in the extraction, and ultrasonic frequency is 30~40KHz;Microwave power is 250~300W, microwave frequency are 2400~2500MHz;Extraction time is at least 40min;Extraction temperature is 40~50 DEG C
By the aloe extract that above-mentioned preparation method obtains compared to traditional extract, active ingredient therein will not Destroyed, and be more enriched with, one layer of water-retaining film can be formed in skin surface during use, keep skin water profit, it is effective to stop Water loss, it can also alleviate fever phenomenon simultaneously for long pernio crowd, avoid scratching, deteriorate pernio symptom.
The NMF is gathered by Sodium Hyaluronate, lauroyl dilactic acid sodium, hydroxypropyl oxinane triol, glycerine Ether -26 in mass ratio 3~6:1~3:2~4:0.5~1 mixes.The NMF has
Both aloe extract, armeniaca mume extract are scattered in glycerine, can extract aloe extract and armeniaca mume Active ingredient in thing mutually blend it is scattered, and it is scattered more uniformly, could both so form water-retaining film evenly, not only Skin wet can be kept, prevents the water loss in skin.Anti-inflammatory sterilization can also be played, the effect of clearing heat for detumescence, is avoided The mocromembrane that hand skin is formed after hand frost is smeared is uneven, especially at pernio, it is impossible to play good Water-saving effect, together When due to pernio generate heat, people scratching further deteriorate pernio symptom.Sodium Hyaluronate of the present invention, lauroyl dilactic acid sodium, hydroxyl Four kinds of propyl group oxinane triol, glycerin polyether -26 material composition NMFs can be very good to play water conservation moisturizing at pernio Effect, the water loss because of heating at pernio is prevented, and due to moisture-keeping function, it is also possible that pernio heating paresthesia is delayed Solution, avoid people from scratching pernio and deteriorate the state of an illness.
Beneficial effects of the present invention:
Hand frost provided by the invention not only has excellent water conservation performance of keeping humidity, keeps skin wet, prevents in skin Water loss, also sterilized with anti-inflammatory, the effect of clearing heat for detumescence, can significantly alleviate pernio symptom, exist suitable for long pernio crowd Use in winter.
Embodiment
The present invention is explained further below in conjunction with specific embodiment, but embodiment does not do any type of limit to the present invention It is fixed.
Embodiment 1
The present embodiment provides a kind of hand frost, by weight, by 4 parts of antierythrite, 7 parts of aloe extract, 5 parts SIMMONDSIA CHINENSIS SEED OIL, 3 parts of Miglyol 812N, 2 parts of lanolin alcohol APEO, 6 parts of armeniaca mume extract, 15 parts Glycerine, 5 parts of aqueous polyurethane, 1 part of vaseline, 2 parts of NMF and 3 parts of hydroxy-ethyl acrylate/acryloyl diformazan It is made after the mixing of base Taurate Copolymer.
The hand frost is prepared as follows:The aloe extract, the armeniaca mume extract and the glycerine are mixed Scattered 30min is closed, then adds the lanolin alcohol APEO and the aqueous polyurethane, mixes scattered 20min, then add Enter the vaseline, the antierythrite and the SIMMONDSIA CHINENSIS SEED OIL, mix scattered 15min, it is sweet to be eventually adding the caprylic capric Oily three esters, the NMF and the hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, mixing 10min are Can.
The armeniaca mume extract is prepared in the following manner:By armeniaca mume in 10s at a temperature of -20 DEG C it is quick-frozen extremely Ice crystal shape, added after crushed 20 mesh sieves in 95vt% ethanol solution, the mass ratio of armeniaca mume and ethanol solution is 1:6;So Zirconia ceramic microballoon is added afterwards, wherein, the mass ratio of armeniaca mume and zirconia ceramic microballoon is 3:1, distilled after stirring Ethanol is removed, obtains armeniaca mume extract.
The aloe extract is prepared in the following manner:According to mass ratio 1:6 is molten by aloe and 80vt% ethanol Liquid mixes, and is extracted in ultrasonic-microwave abstraction instrument, ultrasonic power 70W, ultrasonic frequency 40KHz;Microwave power is 300W, microwave frequency 2500MHz;Extraction time is 40min;Extraction temperature is 50 DEG C;Extract solution is post-processed and obtains aloe Extract.
The NMF is gathered by Sodium Hyaluronate, lauroyl dilactic acid sodium, hydroxypropyl oxinane triol, glycerine Ether -26 in mass ratio 3:1:2:0.5 mixes.
Embodiment 2
The present embodiment provides a kind of hand frost, by weight, by 6 parts of antierythrite, 8 parts of aloe extract, 7 parts SIMMONDSIA CHINENSIS SEED OIL, 5 parts of Miglyol 812N, 3 parts of lanolin alcohol APEO, 7 parts of armeniaca mume extract, 18 parts Glycerine, 6 parts of aqueous polyurethane, 2 parts of vaseline, 3 parts of NMF and 4.5 parts of hydroxy-ethyl acrylate/acryloyl two It is made after the mixing of N-methyltaurine sodium copolymer.
The hand frost is prepared as follows:The aloe extract, the armeniaca mume extract and the glycerine are mixed Scattered 35min is closed, then adds the lanolin alcohol APEO and the aqueous polyurethane, mixes scattered 25min, then add Enter the vaseline, the antierythrite and the SIMMONDSIA CHINENSIS SEED OIL, mix scattered 20min, it is sweet to be eventually adding the caprylic capric Oily three esters, the NMF and the hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, mixing 15min are Can.
The armeniaca mume extract is prepared in the following manner:By armeniaca mume in 12s at a temperature of -18 DEG C it is quick-frozen extremely Ice crystal shape, added after crushed 25 mesh sieves in 95vt% ethanol solution, the mass ratio of armeniaca mume and ethanol solution is 1:7;So Zirconia ceramic microballoon is added afterwards, wherein, the mass ratio of armeniaca mume and zirconia ceramic microballoon is 4:1;After stirring Distillation removes ethanol, obtains the armeniaca mume extract.
The aloe extract is prepared in the following manner:According to mass ratio 1:7 is molten by aloe and 80vt% ethanol Liquid mixes, and is extracted in ultrasonic-microwave abstraction instrument, ultrasonic power 65W, ultrasonic frequency 35KHz;Microwave power is 280W, microwave frequency 2450MHz;Extraction time is 45min;Extraction temperature is 45 DEG C;Extract solution is post-processed and obtains aloe Extract.
The NMF is gathered by Sodium Hyaluronate, lauroyl dilactic acid sodium, hydroxypropyl oxinane triol, glycerine Ether -26 in mass ratio 4:2:3:0.8 mixes.
Embodiment 3
The present embodiment provides a kind of hand frost, by weight, by 8 parts of antierythrite, 9 parts of aloe extract, 10 parts SIMMONDSIA CHINENSIS SEED OIL, 7 parts of Miglyol 812N, 4 parts of lanolin alcohol APEO, 8 parts of armeniaca mume extract, 20 The glycerine, 7 parts of aqueous polyurethane, 3 parts of vaseline, 4 parts of NMF and 6 parts of hydroxy-ethyl acrylate/acryloyl two of part It is made after the mixing of N-methyltaurine sodium copolymer.
The hand frost is prepared as follows:The aloe extract, the armeniaca mume extract and the glycerine are mixed Scattered 40min is closed, then adds the lanolin alcohol APEO and the aqueous polyurethane, mixes scattered 30min, then add Enter the vaseline, the antierythrite and the SIMMONDSIA CHINENSIS SEED OIL, mix scattered 25min, it is sweet to be eventually adding the caprylic capric Oily three esters, the NMF and the hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, mixing 20min are Can.
The armeniaca mume extract is prepared in the following manner:By armeniaca mume in 15s at a temperature of -15 DEG C it is quick-frozen extremely Ice crystal shape, added after crushed 30 mesh sieves in 95vt% ethanol solution, the mass ratio of armeniaca mume and ethanol solution is 1:9;So Zirconia ceramic microballoon is added afterwards, wherein, the mass ratio of armeniaca mume and zirconia ceramic microballoon is 6:1;Distilled after stirring Ethanol is removed, obtains armeniaca mume extract.
The aloe extract is prepared in the following manner:According to mass ratio 1:9 is molten by aloe and 80vt% ethanol Liquid mixes, and is extracted in ultrasonic-microwave abstraction instrument, ultrasonic power 60W, ultrasonic frequency 30KHz;Microwave power is 250W, microwave frequency 2400MHz;Extraction time is 50min;Extraction temperature is 40 DEG C;Extract solution is post-processed and obtains aloe Extract.
The NMF is gathered by Sodium Hyaluronate, lauroyl dilactic acid sodium, hydroxypropyl oxinane triol, glycerine Ether -26 in mass ratio 6:3:4:1 mixes.
Test example
Above-described embodiment 1~3 is repeated, obtains enough hand frosts.Made simultaneously with conventional hand frost product of the prior art For control group, choose 40 pernio patients December and be divided into 4 groups of carry out usage experiences, amount to and continue one month.Examination Sensory experience situation is counted after the completion of testing and is given a mark, its result is as shown in Table 1 and Table 2.
The sensory experience standard of table 1
The marking table on probation of table 2
As can be seen from the above table, guarantor can preferably be played compared to the hand frost articles for use of routine, hand lotion provided by the invention Water moisture-keeping function, and the heating itch phenomenon for pernio has obtained obvious suppression.

Claims (8)

1. a kind of hand frost, it is characterised in that by weight, by 4~8 parts of antierythrite, 7~9 parts of aloe extract, 5 ~10 parts of SIMMONDSIA CHINENSIS SEED OIL, 3~7 parts of Miglyol 812N, 2~4 parts of lanolin alcohol APEO, 6~8 parts Armeniaca mume extract, 15~20 parts of glycerine, 5~7 parts of aqueous polyurethane, 1~3 part of vaseline, 2~4 parts of NMF It is made with after 3~6 parts of hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers mixing.
2. hand frost according to claim 1, it is characterised in that the armeniaca mume extract is prepared in the following manner: By armeniaca mume in 10~15s at a temperature of -15~-20 DEG C it is quick-frozen to ice crystal shape, added after crushed 20~30 mesh sieves In 95vt% ethanol solution, distillation removal ethanol, obtains the armeniaca mume extract after stirring.
3. hand frost according to claim 2, it is characterised in that the mass ratio of the armeniaca mume and the ethanol solution is 1: 6~9.
4. hand frost according to claim 2, it is characterised in that after the armeniaca mume after crushing is mixed with ethanol solution, add Enter zirconia ceramic microballoon, wherein, the mass ratio of armeniaca mume and zirconia ceramic microballoon is 3~6:1, distill and go after stirring Except ethanol.
5. hand frost according to claim 1, it is characterised in that the aloe extract is prepared in the following manner:Will Aloe mixes with 80vt% ethanol solution, is extracted in ultrasonic-microwave abstraction instrument, and extract solution is post-processed into acquisition aloe carries Take thing.
6. hand frost according to claim 5, it is characterised in that the mass ratio of the aloe and the ethanol solution is 1:6 ~9.
7. hand according to claim 5 frost, it is characterised in that ultrasonic power is 60~70W in the extraction, ultrasonic wave Frequency is 30~40KHz;Microwave power is 250~300W, and microwave frequency is 2400~2500MHz;Extraction time is at least 40min;Extraction temperature is 40~50 DEG C.
8. hand frost according to claim 1, it is characterised in that the NMF is by Sodium Hyaluronate, lauroyl lactoyl Sodium lactate, hydroxypropyl oxinane triol, glycerin polyether -26 in mass ratio 3~6:1~3:2~4:0.5~1 mixes.
CN201711317760.5A 2017-12-12 2017-12-12 A kind of hand frost Pending CN107802557A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173221A (en) * 2013-05-23 2014-12-03 伽蓝(集团)股份有限公司 Novel application of prunus mume extract
CN105411958A (en) * 2015-12-30 2016-03-23 苟秀芹 Hand cream
CN105596234A (en) * 2015-12-30 2016-05-25 广州蜜妆生物科技有限公司 Wash-resisting hand cream and preparing method thereof
CN105769723A (en) * 2014-12-25 2016-07-20 天长市地震办公室 Hand cream
CN107281004A (en) * 2016-03-31 2017-10-24 科思创聚合物(中国)有限公司 Cosmetic composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173221A (en) * 2013-05-23 2014-12-03 伽蓝(集团)股份有限公司 Novel application of prunus mume extract
CN105769723A (en) * 2014-12-25 2016-07-20 天长市地震办公室 Hand cream
CN105411958A (en) * 2015-12-30 2016-03-23 苟秀芹 Hand cream
CN105596234A (en) * 2015-12-30 2016-05-25 广州蜜妆生物科技有限公司 Wash-resisting hand cream and preparing method thereof
CN107281004A (en) * 2016-03-31 2017-10-24 科思创聚合物(中国)有限公司 Cosmetic composition

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