CN107802556A - A kind of moisture-keeping composition and contain said composition cosmetics - Google Patents

A kind of moisture-keeping composition and contain said composition cosmetics Download PDF

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Publication number
CN107802556A
CN107802556A CN201711313844.1A CN201711313844A CN107802556A CN 107802556 A CN107802556 A CN 107802556A CN 201711313844 A CN201711313844 A CN 201711313844A CN 107802556 A CN107802556 A CN 107802556A
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extract
moisture
wolfberry fruit
mass ratio
composition
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陈海佳
葛啸虎
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

A kind of moisture-keeping composition of the present invention, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is (2~8):(0.5~5):(1~5), wolfberry fruit extract include Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 0.5:1~3:1, the present invention is composition from wolfberry fruit extract, using Fructus lycii P.E and matrimony vine leaf extract, rationally compounding is used in conjunction with down, utilize both active ingredient, being capable of activating cell, firm skin, prevent water loss, the moistening effect to keep the skin wet, addition has whitening simultaneously, skin-active, the Herba Lysimachiae foenumgraeci extract of oxygen radical can be reduced, apple seed extract, acted synergistically with wolfberry fruit extract, play the synergy synergy of moisturizing, under plurality of Chinese extract certain limit ratio, act synergistically, product is set to be obviously improved skin quality, improve skin elasticity, the moistening effect to keep the skin wet, positive effect is higher than individually addition one of which or two kinds of extracts.

Description

A kind of moisture-keeping composition and contain said composition cosmetics
Technical field
The present invention relates to cosmetic technical field, is specifically related to a kind of moisture-keeping composition and is made up containing said composition Product.
Background technology
It is everyone nature, especially women to like to be beautiful, then as the quickening of people's rhythm of life, operating pressure and life The increasingly increase of pressure living, and environmental pollution and the careless reason of diet, the growth at simultaneous age, the skin of people Skin engenders many problems, and such as originally coloured and dazzling it is more and more gradually to become long spot, wrinkle on the face, therefore to a lot Women brings puzzlement.
It is one of pathomechanism of aged appearance that skin water content, which gradually reduces, when the water content of cuticula is less than 10% When, there is crack in dry skin, furfur, imbricate keratinocyte layer arranged in parallel, and skin is easily by external environment physics The erosion of factor, water, electrolyte in skin also easily evaporate or are lost in.Skin moisture-keeping be ensure cuticula barrier function and The most important basic means improved looks.Moisturizer is mainly by preventing the loss of moisture in skin and absorbing external environment Moisture reach the purpose that skin includes certain moisture, the moisturizing active component more approved at present is bionical dose of class, such as god Through acid amides, hyaluronic acid, pyrrolones carboxylic acid sodium etc., after being absorbed by skin, it can be combined with the free water in skin and be allowed to not allow It is volatile so as to play moisture-keeping function, subject matter is such components unstable chemcial property, and the content in product system is normal Because internal and external factor gradually reduces, effective threshold value is unable to reach, the moistening effect of itself is not notable.
The content of the invention
The cosmetic of a kind of moisture-keeping composition and application said composition is provided it is an object of the invention to overcome above mentioned problem Product, the moisture-keeping composition are directed to dry skin problem, using the mutual synergy of the active component of plurality of Chinese extract, with Play moisture-keeping function.
To achieve the above object, the present invention adopts the technical scheme that a kind of moisture-keeping composition, containing wolfberry fruit extract, smokes Clothing grass extract, apple seed extract, three's mass ratio are (2~8):(0.5~5):(1~5), wolfberry fruit extract include matrimony vine Seed extract and matrimony vine leaf extract, the mass ratio of the two are 0.5:1~3:1.
Preferably, the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio are (3~7): (1~4.5):(2~4).
Preferably, the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio are (4~6): (2~4):(3~4).
Preferably, the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio for (4.5~ 6):(3~4):(3~4).
Preferably, the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio for (4.5~ 5):(3~3.5):(3~4).
Preferably, the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio are 4.5:3:3.
Preferably, the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio are 5:3.5:4.
Preferably, the Fructus lycii P.E and matrimony vine leaf extract, the mass ratio of the two are 1.5:1.
Preferably, the Fructus lycii P.E and matrimony vine leaf extract, the mass ratio of the two are 1.8:1.
A kind of moisture-keeping cosmetics, contain described moisture-keeping composition.
Moisture-keeping composition main component and effect of the present invention are as follows:
Matrimony vine:The fruit of Chinese wolfberry is the plant of eggplant mesh Solanaceae Lycium, and fruit claims the fruit of Chinese wolfberry, and tender leaf claims matrimony vine head, frequent species For matrimony vine, main medical species are lycium barbarum.Function is nourishing liver and kidney with curing mainly, benefiting shrewd head, for consumption consumptive loss, waist and knee Ache, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, blurred vision.Contain 14 kinds of amino acid in the fruit of Chinese wolfberry, and containing glycine betaine, The special nutrient compositions such as zeaxanthin, physalin, make it have outstanding health-care efficacy.The fruit of Chinese wolfberry contains abundant The required nutriment of the healthy eye such as carrotene, multivitamin and calcium, iron, therefore have the work(of improving eyesight, it is commonly called as " bright eye ".
Contained LBP-X, the carrotene of B mono-, flavonoids are all the antioxidants of strength in matrimony vine, along with matrimony vine institute The trace elements of selenium and the synergy of vitamin E contained, constitute powerful anti-oxidant army;In addition, vitamin A can maintain The growth and differentiation of skin tissue, prevent dry skin and follicular keratosis, so as to play a part of beautifying face and moistering lotion, Glycerin.
Folium lycii is commonly called as day essence grass, and mainly there is in (Tibetans) medicine kidney-tonifying sperm-generating, nourishing the liver, improving eyesight the work such as to calm the nerves in tradition With,《Compendium of Materia Medica》Middle title folium lycii " thering is relieving restlessness benefit will to mend general debility, high aspiration gas, except heat toxin, sore swells to be dissipated, except wind improving eyesight " it Effect.It was found that the active component of folium lycii and Chinese wolfberry fruit are basically identical, and Chinese holly is even more than on some nutrients Fructus lycii is real.The report of the pharmacological properties of folium Lycii total flavone extract is less.The folium Lycii total flavone extract having now found that Pharmacological activity is only resided within the level of antioxidation activity.
Lavender:Lavender category Labiatae lavender category, originates in Mediterranean, throughout Europe and Oceania archipelago, Planted extensively in Britain and Yugoslavia, present Yunnan successful introduction afterwards.Herba Lysimachiae foenumgraeci extract has certain removing to DPPH Ability, its antioxidation is close with Vc, and 2.0mg/ml Herba Lysimachiae foenumgraeci extract, up to 91.48%, shows DPPH clearance rate Herba Lysimachiae foenumgraeci extract has good antioxidation activity.
Apple Seeds:Fat content is generally 22%~27% in Apple Seeds, and unsaturated fatty acid content is 90% or so, especially Its linoleic acid, its content account for the 46%~52% of fatty acid total amount, and apple seed extract can be supplemented directly from natural plant Thing (apple) sex hormone, plant (apple) hormone, and trigger the sex hormone of human body itself to secrete;Promote skin scar reparation, Promote the collagen and keratin normal growth of skin area.
Beneficial effects of the present invention:The present invention is composition from wolfberry fruit extract, utilizes Fructus lycii P.E and folium lycii Rationally compounding is used in conjunction with down extract, using both active ingredient, can activating cell, firm skin, prevent moisture stream The moistening effect lose, to keep the skin wet, while add with whitening, skin-active, the Herba Lysimachiae foenumgraeci extract that oxygen radical can be reduced, apple Fruit seed extract, acts synergistically with wolfberry fruit extract, the synergy synergy of moisturizing is played, in plurality of Chinese extract one Determine under range scale, act synergistically, product is obviously improved skin quality, improve skin elasticity, the moisturizing to keep the skin wet Effect, positive effect is higher than individually addition one of which or two kinds of extracts.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is (2~8):(0.5~5):(1~5), wolfberry fruit extract include Fructus lycii P.E and matrimony vine leaf extract, the mass ratio of the two For 0.5:1~3:1.
Embodiment 1
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 2:0.5:1, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 0.5:1.
Using the cosmetics of above-mentioned moisture-keeping composition composition, including following mass percent composition, contain above-mentioned moisturizing Old Chinese medicine composition 15%, 15% part of isononyl isononyl alcohol ester, polyacrylamide 4%, sorbic acid agent 0.5%, remaining for go from Sub- water.
The preparation method of above-mentioned cosmetics, comprises the following steps:
1) preparation of fructus lycii extracted solution:
A) prepared by medlar extract liquid:The fruit of Chinese wolfberry is crushed, is placed in Chinese medicament extracting device, add 8 times amount 90 DEG C go from Sub- water, twice, each extraction 58 minutes, filtering, merge extract solution, are concentrated under reduced pressure into the 1/3 of original volume every time for extraction, then with 5000r/min rotating speed centrifuges 10 minutes, takes supernatant, continues to be concentrated into the 1/4 of liquid volume, it is standby to obtain Aqueous extracts.
B) prepared by matrimony vine leaf extract:By folium lycii drying, pulverize and sieve, obtain coarse powder;B) 1kg coarse powder is added and extracted In tank (TQ-3.0), 10kg drinking water is added, soaks 30min;C) heating extraction 90 minutes, extract solution is taken out, filtering, is obtained Filtrate;D) 6kg drinking water is added, heating extraction 60 minutes, filtering, obtains filtrate;E) combining step (c) and (d) are obtained Filtrate, about 3kg (relative density 1.04) is concentrated under reduced pressure into, is cooled to less than 40 DEG C;Then, under stirring, slowly The ethanol of percent by volume 95% is added, concentration of alcohol is 65% in the mixed liquor for making to finally give;It is f) closed to place 12 hours, Make precipitation complete;G) supernatant is taken, ethanol is recovered under reduced pressure, is concentrated into 2kg:Concentrate is while hot with 500 mesh filter-cloth filterings.
C) ratio mixing more than the matrimony vine leaf extract in the medlar extract liquid in step a) and step b) will be stated, is made Wolfberry fruit extract.
Herba Lysimachiae foenumgraeci extract, apple seed extract are realized using prior art.
3) wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract are dissolved in isononyl isononyl alcohol ester, are warmed to 30 DEG C when, add polyacrylamide, add water under agitation, be eventually adding potassium sorbate and stir evenly, be cooled to room temperature.
Embodiment 2
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 3:1:2, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 0.8:1.
Using the cosmetics of above-mentioned moisture-keeping composition composition, including following mass percent composition, contain above-mentioned moisturizing Old Chinese medicine composition 16%, 15% part of isononyl isononyl alcohol ester, polyacrylamide 4%, sorbic acid agent 0.5%, remaining for go from Sub- water.The cosmetics preparation method such as embodiment 1.
Embodiment 3
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 4:2:3, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 1:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 15.5%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.
The preparation method of above-mentioned moisturizing cream, comprises the following steps:
1) wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract first are dissolved with portions of de-ionized water, filtering is stand-by; 2) white oil, albolene, glycerin monostearate, mixed 75 DEG C -80 DEG C of alcohol stir;Remaining deionized water, potassium sorbate 75 DEG C -80 DEG C stir;Both the above mixture is successively pumped into emulsification pot, homogeneous 5 minutes, stirring is cooled to 40 DEG C, and 3) plus Enter the wolfberry fruit extract filtered, Herba Lysimachiae foenumgraeci extract, apple seed extract, stir evenly, be cooled to room temperature.Wolfberry fruit extract Prepare same as Example 1.
Embodiment 4
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 4.5:3:3, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 1.5:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 16%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.The moisturizing cream preparation method such as embodiment 3.
Embodiment 5
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 5:3.5:4, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 1.8:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 18%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.The moisturizing cream preparation method such as embodiment 3.
Embodiment 6
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 6:4:3.5, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 2:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 17.5%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.The moisturizing cream preparation method such as embodiment 3.
Embodiment 7
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 7:4.5:4, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 2.5:1.
Using said composition be used for prepare moisturizing emulsion, including following mass percent composition, containing above-mentioned moisturizing it is old in Drug composition 18.5%, monoglyceride 8%, vaseline 2.5%, dimethicone 6%, glycerine 5%, mixed alcohol 10%, white oil 5%, 1,3-BDO 20.0%, card ripple 940 0.5%, triethanolamine adjust pH5-7, potassium sorbate 0.5%, surplus deionization in right amount Water.
The preparation method of the moisturizing emulsion, comprises the following steps, and 1) first dissolved with 1,3-BDO and portions of de-ionized water Wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, filtering are stand-by;2) white oil, vaseline, monoglyceride, alcohol, diformazan are mixed 75 DEG C -80 DEG C of base silicone oil stirs;3) remaining deionized water, glycerine, card ripple 940,75 DEG C -80 DEG C of preservative stir; 4) both the above mixture is successively pumped into emulsification pot, homogeneous 3 minutes, triethanolamine is added and adjusts pH5-7 in right amount;5) stirring cooling To 40 DEG C, wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, the apple seed extract filtered is added, stirs evenly, is cooled to room temperature.
Embodiment 8
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three's mass ratio is 8:5:5, wolfberry fruit extract includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 3:1.
Using said composition be used for prepare moisturizing emulsion, including following mass percent composition, containing above-mentioned moisturizing it is old in Drug composition 20%, monoglyceride 8%, vaseline 2.5%, dimethicone 6%, glycerine 5%, mixed alcohol 10%, white oil 5%, 1, 3- butanediols 20.0%, card ripple 940 0.5%, triethanolamine adjust pH5-7, potassium sorbate 0.5%, balance deionized water in right amount. The moisturizing emulsion preparation method such as embodiment 7.
Control group 1
A kind of moisturizing cream, including following mass percent composition, contain wolfberry fruit extract 16%, white oil 8%, Bai Fanshi Woods 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, balance deionized water.The moisturizing cream preparation method Such as embodiment 3.Wolfberry fruit extract component content is same as Example 4.
Control group 2
A kind of moisturizing cream, including following mass percent composition, contain Herba Lysimachiae foenumgraeci extract 16%, white oil 8%, white Vaseline 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, balance deionized water.It is prepared by the moisturizing cream Method such as embodiment 3.
Control group 3
A kind of moisturizing cream, including following mass percent composition, contain apple seed extract 16%, white oil 8%, white Vaseline 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, balance deionized water.It is prepared by the moisturizing cream Method such as embodiment 3.
Control group 4
A kind of moisture-keeping composition, containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, both mass ratioes are 4.5:3, matrimony vine extraction Thing includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 1.5:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 16%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.The moisturizing cream preparation method such as embodiment 3.
Control group 5
A kind of moisture-keeping composition, containing wolfberry fruit extract, apple seed extract, both mass ratioes are 4.5:3, matrimony vine extraction Thing includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 1.5:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 16%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.The moisturizing cream preparation method such as embodiment 3.
Control group 6
A kind of moisture-keeping composition, containing Herba Lysimachiae foenumgraeci extract, apple seed extract, both mass ratioes are 3:3, matrimony vine extraction Thing includes Fructus lycii P.E and matrimony vine leaf extract, and the mass ratio of the two is 1.5:1.
Using said composition be used for prepare moisturizing cream, including following mass percent composition, containing above-mentioned moisturizing it is old in It is drug composition 16%, white oil 8%, albolene 10%, glycerin monostearate 12%, mixed alcohol 4%, preservative 0.5%, remaining Measure deionized water.The moisturizing cream preparation method such as embodiment 3.
Control group 7
This control group is that wherein wolfberry fruit extract is Fructus lycii P.E with the different places of embodiment 4.
Control group 8
This control group is that wherein wolfberry fruit extract is matrimony vine leaf extract with the different places of embodiment 4.
Control group 9
This control group is that the Fructus lycii P.E, folium lycii wherein in wolfberry fruit extract carry with the different places of embodiment 4 It is 0.2 to take amount of substance ratio:1.
Control group 10
This control group is that the Fructus lycii P.E, folium lycii wherein in wolfberry fruit extract carry with the different places of embodiment 4 It is 4 to take amount of substance ratio:1.
Control group 11
This control group is with the different places of embodiment 4, wherein containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, Apple Seeds Extract, three's mass ratio are 1:0.3:0.5.
Control group 12
This control group is with the different places of embodiment 4, wherein containing wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, Apple Seeds Extract, three's mass ratio are 9:7:6.
Experiment effect
1st, guinea pig skin stimulation test
The composite skin care product of 0.5g embodiments 1~8 is respectively taken, being diluted to 100g using deionized water is configured to given the test agent. Given the test agent using skin irritation test method (《Cosmetics health specification》2007 editions toxicology test methods) tested.
Experimental animal:Cavy body weight 250g~300g.
Experimental result:Through 14 days Skin Irritation Tests, stimulate the reaction is had no.
2nd, sample moistening effect
2.1 experimental method
According to prior art (Wang Libo, Yan Huiju etc., the measure new method of cosmetics performance of keeping humidity, toothpaste industry, 2006 The 3rd phase of year) measure, bend side in candidate or so forearm and mark 3 × 3cm2The square Experimental Area of size, guarantor is used as using left arm The test zone of wet product, the corresponding symmetrical region of right arm are blank control, then every with Corneometer CM825 test detections The moisture at individual experiment position, is repeated 5 times, draws average value respectively.With formula (1) calculated hydration rate;
Hydration rate=100% × (test group-blank value)/blank value;
3.2 experimental result
Table 1 is embodiment 1~8 and the moistening effect testing result of control group 1~12
As shown in Table 1, three kinds of the moisture-keeping composition of the embodiment of the present invention 1~8 is respectively provided with good moisture-keeping function, wherein With the best results of embodiment 4~6.
Control group 1~3 is respectively only using wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, the preserving moisture and protecting skin of apple seed extract Product, above-mentioned 1~3 condition same as Example 4 of control group, it can be seen that a kind of extract in three kinds is used alone, has one Determine moisture-keeping functions, but hydration rate is substantially less than the present invention, and control group 4~6 is using two kinds of any combination in three kinds of extracts The skin care item of acquisition are identical with the other conditions of embodiment 4, it can be seen that relative to extract is used alone, moisturizing has lifting, but Its effect also has differences with the present invention, illustrates the composition of the present invention and needs three to act synergistically down jointly, can just reach notable Moistening effect.
The wolfberry fruit extract that control group 7~8 uses is respectively to select Fructus lycii P.E, shield prepared by matrimony vine leaf extract Skin product, its hydration rate is lower relative to both compounding uses, shows, in the case where two kinds of extracts are used in conjunction with, moistening effect can increase Add, the Fructus lycii P.E and the ratio of matrimony vine leaf extract that control group 9~10 is are in addition to the present invention, it is seen then that its moisturizing is imitated Fruit illustrates only in the significant moistening effect of competence exertion only in special ratios not as the present invention.
And control group 11~12 is from identical component, under the conditions of identical preparation method, its formula rate is in this hair Outside bright specific proportion, its effect is nothing like the effect of the present invention, it was demonstrated that, composition of the invention is only in spy The significant moistening effect of competence exertion in certainty ratio.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention God any modification, equivalent substitution and improvements done etc., should be included within the scope of protection of the invention with principle.

Claims (10)

1. a kind of moisture-keeping composition, it is characterised in that contain wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple seed extract, three Mass ratio is (2~8):(0.5~5):(1~5), wolfberry fruit extract include Fructus lycii P.E and matrimony vine leaf extract, the two Mass ratio be 0.5:1~3:1.
2. moisture-keeping composition according to claim 1, it is characterised in that the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple Fruit seed extract, three's mass ratio are (3~7):(1~4.5):(2~4).
3. moisture-keeping composition according to claim 1, it is characterised in that the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple Fruit seed extract, three's mass ratio are (4~6):(2~4):(3~4).
4. moisture-keeping composition according to claim 1, it is characterised in that the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple Fruit seed extract, three's mass ratio are (4.5~6):(3~4):(3~4).
5. moisture-keeping composition according to claim 1, it is characterised in that the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple Fruit seed extract, three's mass ratio are (4.5~5):(3~3.5):(3~4).
6. moisture-keeping composition according to claim 1, it is characterised in that the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple Fruit seed extract, three's mass ratio are 4.5:3:3.
7. moisture-keeping composition according to claim 1, it is characterised in that the wolfberry fruit extract, Herba Lysimachiae foenumgraeci extract, apple Fruit seed extract, three's mass ratio are 5:3.5:4.
8. moisture-keeping composition according to claim 1, it is characterised in that Fructus lycii P.E and the folium lycii extraction Thing, the mass ratio of the two are 1.5:1.
9. moisture-keeping composition according to claim 1, it is characterised in that Fructus lycii P.E and the folium lycii extraction Thing, the mass ratio of the two are 1.8:1.
A kind of 10. moisture-keeping cosmetics, it is characterised in that:Contain any described moisture-keeping composition of claim 1 to 9.
CN201711313844.1A 2017-12-07 2017-12-07 A kind of moisture-keeping composition and contain said composition cosmetics Withdrawn CN107802556A (en)

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