CN107789479A - 一种用于治疗糖尿病的中药 - Google Patents
一种用于治疗糖尿病的中药 Download PDFInfo
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- CN107789479A CN107789479A CN201610743611.4A CN201610743611A CN107789479A CN 107789479 A CN107789479 A CN 107789479A CN 201610743611 A CN201610743611 A CN 201610743611A CN 107789479 A CN107789479 A CN 107789479A
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- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种用于治疗糖尿病的中药，它是由下列重量份配比的原料组成：西洋参5～7份、黄芪25～30份、淮山药10～15份、黄芩10～15份、生石膏15～20份、沙参10～15份、知母10～15份、麦冬10～15份、黄精20～25份、桑螵蛸10～15份、天花粉10～15份、黄连5～7份、鸡内金5～7份、三七2～5份、葛根5～10份、五味子5～10份。本发明治疗糖尿病的中药全方共奏清热保津、益气养阴、涩精化瘀之效。本发明治疗糖尿病的中药能有效控制血糖，还可降低血清甘油三酯和胆固醇对脂质代谢紊乱有调节作用。
Description
技术领域
本发明涉及一种以中草药为原料的中药，尤其是涉及一种用于治疗糖尿病的中药。
背景技术
糖尿病属于中医的 “消渴”范畴，以多饮、多食、多尿、消瘦或尿有甜味为特征。其发病机理为燥热伤阴，阴津亏耗，病理特点以阴虚为本，燥热为标，互为因果。临床以三多一少和高血糖为标志。高脂血症是糖尿病的常见并发症之一，是产生动脉粥样硬化的重要原因。为防止糖尿病见并发症的发生，防止脂质代谢紊乱，除有效地控制血糖外，还需加强降脂治疗。
治疗糖尿病。常用的为消渴丸，其含有中药组分黄芪、生地、天花粉及西药组分优降糖。中医中药治疗糖尿病不但在治疗症状方面有优势，在解除症状的同时，身体的功能得到调整，并可使患者的体质状况得到改善。由于中医药疗效好，毒副作用小，容易被患者所接受。因此寻求一种高效治疗糖尿病的药物是急待解决的问题。本发明人经过多年临床研究，终于找到一种用于治疗糖尿病的中药。
发明内容
本发明的目的在于提供一种用于治疗糖尿病的中药。
本发明的目的是通过下述技术方案来实现的：
按照本发明的用于治疗糖尿病的中药，其特征在于，它是由下列重量份配比的原料组成：
西洋参5～7份、黄芪25～30份、淮山药10～15份、黄芩10～15份、生石膏15～20份、沙参10～15份、知母10～15份、麦冬10～15份、黄精20～25份、桑螵蛸10～15份、天花粉10～15份、黄连5～7份、鸡内金5～7份、三七2～5份、葛根5～10份、五味子5～10份。
按照本发明所述的用于治疗糖尿病的中药，其特征在于，它是由下列重量份配比的原料组成：
西洋参6份、黄芪30份、淮山药10份、黄芩10份、生石膏20份、沙参15份、知母10份、麦冬10份、黄精20份、桑螵蛸15份、天花粉10份、黄连6份、鸡内金6份、三七3份、葛根5份、五味子10份。
按照本发明所述的用于治疗糖尿病的中药，其特征在于，其中加入药学上可接受的载体制成适于药用的制剂。
本发明的中药，在制备成药剂时可加入药学上可接受的载体，所述药学上可接受的载体可以是：淀粉、蔗糖、乳糖、甘露糖醇、硅衍生物、纤维素类及其衍生物、藻酸盐、明胶、聚乙烯吡咯烷酮、甘油、土温80 、琼脂、碳酸钙、碳酸氢钙、表面活性剂、聚乙二醇、环糊精、p-环糊精、磷脂类材料、高岭土、滑石粉、硬脂酸钙、硬脂酸镁等。本发明的中药可以是任何可药用的剂型，这些剂型包括：酒剂、片剂、糖衣片剂、薄膜衣片剂、肠溶衣片剂、胶囊剂、硬胶囊剂、软胶囊剂、口服液、口含片、颗粒剂、丸剂、散剂、膏剂、丹剂、混悬剂、粉剂、溶液剂、注射剂、栓剂、软膏剂、硬膏剂、霜剂、喷雾剂、滴剂、贴剂。
本发明的制剂，优选的是口服剂型如：酒剂、片剂、胶囊剂、口服液、口含片、颗粒剂、丸剂、散剂、混悬剂、粉剂、滴剂、滴丸剂。更优选的中药制剂是酒剂、溶液剂、胶囊剂、片剂、颗粒剂。
1、一种治疗糖尿病的中药颗粒剂制备方法：取所述重量的各原料混合，加水煎煮两次，第一次1.5～2 小时，第二次0.5～1小时，合并两次煎液，滤过，滤液浓缩至80～85℃时，相对密度1.08～1.10 的清膏，加入乙醇使清膏含醇量达70 % ，静置24 小时，回收乙醇，在50～55℃时浓缩至相对密度1.30～1.32 的清膏，干燥，粉碎成细粉，再加入适量蔗糖和可溶性淀粉，乙醇制粒，干燥后装袋，即得。
2、一种治疗糖尿病的中药溶液剂制备方法：将所述重量的各原料混合，加水煎煮两次，第一次1.5～2 小时，第二次0 .5～1小时，合并两次煎液，滤过，滤液浓缩至规定的浓度，放冷，原液灌封，辐照灭菌，检验后，包装成品，即得。
本发明治疗糖尿病的中药既能清热泻火，养阴生津，又健脾益气、滋阴补肾。选择西洋参、黄芪、淮山药健脾益气；选择黄芩、黄连、生石膏清热泻火；选择沙参、知母、麦冬、天花粉、黄精养阴生津；选择桑螵蛸涩精缩尿；选择鸡内金助脾强健，化饮食中糖质为津液；选择三七活血化瘀；选择葛根能升阳气；选择五味子收敛固涩、益气生津、补肾宁心。全方共奏清热保津、益气养阴、涩精化瘀之效。本发明治疗糖尿病的中药能有效控制血糖，还可降低血清甘油三酯和胆固醇对脂质代谢紊乱有调节作用。
具体实施方式
以下各实施例仅用于对本发明进行解释说明，并不构成对权利要求范围的限定，本领域技术人员根据说明书内容可以想到的其它替代手段，均应在本发明权利要求的保护范围之内。
实施例：由下列重量份原料组成：
西洋参6份、黄芪30份、淮山药10份、黄芩10份、生石膏20份、沙参15份、知母10份、麦冬10份、黄精20份、桑螵蛸15份、天花粉10份、黄连6份、鸡内金6份、三七3份、葛根5份、五味子10份。
实施例的中药颗粒剂制备方法：取所述重量的各原料混合，加水煎煮两次，第一次1.5～2 小时，第二次0 .5～1小时，合并两次煎液，滤过，滤液浓缩至80～85℃时，相对密度1.08～1.10 的清膏，加入乙醇使清膏含醇量达70 % ，静置24 小时，回收乙醇，在50～55℃时浓缩至相对密度1.30～1.32 的清膏，干燥，粉碎成细粉，再加入适量蔗糖和可溶性淀粉，乙醇制粒，干燥后装袋，即得。
实施例的中药片剂制备方法：将上述重量各原料混合，碾成细粉过100目细筛后，制成片剂即得。
实施例的中药丸剂制备方法：将上述重量各原料混合，碾成细粉后过80 目筛后，制成丸剂即得。
实施例的中药散剂制备方法：将上述重量各原料分别干燥粉碎至120目细分，再将全部粉剂组分按所述比例混合后，在110℃下进行灭菌20分钟，即得。
实施例的中药胶囊剂制备方法：将上述的散剂装入胶囊即得。
本发明中药对治疗糖尿病的效果：
疗效观察：1、空腹血糖，2、糖化血红蛋白，3、总胆固醇、甘油三酯，4、血、尿、大便常规及心电图、肝肾功能。
疗效标准：参照卫生部《中药新药治疗消渴病的临床研究指导原则》拟定。
治疗结果：治疗糖尿病患者87例中；显效53例，占60.9%；有效23例，占26.4%；无效11例，占12.6%；总有效率占87.4%。
Claims (3)
1.一种用于治疗糖尿病的中药，其特征在于，它是由下列重量份配比的原料组成：
西洋参5～7份、黄芪25～30份、淮山药10～15份、黄芩10～15份、生石膏15～20份、沙参10～15份、知母10～15份、麦冬10～15份、黄精20～25份、桑螵蛸10～15份、天花粉10～15份、黄连5～7份、鸡内金5～7份、三七2～5份、葛根5～10份、五味子5～10份。
2.根据权利要求1所述的用于治疗糖尿病的中药，其特征在于，它是由下列重量份配比的原料组成：
西洋参6份、黄芪30份、淮山药10份、黄芩10份、生石膏20份、沙参15份、知母10份、麦冬10份、黄精20份、桑螵蛸15份、天花粉10份、黄连6份、鸡内金6份、三七3份、葛根5份、五味子10份。
3.根据权利要求1或2所述的用于治疗糖尿病的中药，其特征在于，其中加入药学上可接受的载体制成适于药用的制剂。
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108524720A (zh) * | 2018-04-28 | 2018-09-14 | 曾发忠 | 一种治疗糖尿病的中药组合物及其制备方法 |
| RU2806632C1 (ru) * | 2020-02-26 | 2023-11-02 | Сучжоу Реген-Фарматек Ко., Лтд. | Композиция традиционной китайской медицины, способ ее приготовления и ее применение |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524720A (zh) * | 2018-04-28 | 2018-09-14 | 曾发忠 | 一种治疗糖尿病的中药组合物及其制备方法 |
| RU2806632C1 (ru) * | 2020-02-26 | 2023-11-02 | Сучжоу Реген-Фарматек Ко., Лтд. | Композиция традиционной китайской медицины, способ ее приготовления и ее применение |
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