CN107789362A - A kind of gravel for treating birds ventriculitis and preparation method thereof - Google Patents
A kind of gravel for treating birds ventriculitis and preparation method thereof Download PDFInfo
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- CN107789362A CN107789362A CN201610782840.7A CN201610782840A CN107789362A CN 107789362 A CN107789362 A CN 107789362A CN 201610782840 A CN201610782840 A CN 201610782840A CN 107789362 A CN107789362 A CN 107789362A
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- gravel
- ventriculitis
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- birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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Abstract
The present invention relates to a kind of gravel for treating birds ventriculitis and preparation method thereof, belong to pharmaceutical technology field.The gravel is made up of calcium silicates, calcium carbonate, Amoxicillin, de- mould dose.Gravel provided by the invention can retain 37 days in muscular stomach, help grate foods and it is preferably digested and assimilated, and supplement calcium, while can adjust gastric acid secretion, kill or suppress mould breeding, can effectively prevent and treat the generation of proventriculitis.Its preparation technology is simple, quality controllable, is suitable for industrialized large-scaled production, and is with a wide range of applications.
Description
Technical field
The present invention relates to a kind of gravel for treating birds ventriculitis and preparation method thereof, belong to veterinary drug technical field.
Background technology
Ventriculitis is a kind of communicable disease of birds, mainly encroaches on muscular stomach, so as to influence the digestion of chicken, is absorbed, production
Performance.
Ventriculitis predisposing factors mainly has following several situations：(1) feed：Feed produces mould, toxin, and feed nutrition is not
Equilibrium, crude protein content is too low, hypovitaminosis, Content of Biogenic Amines height etc..(2) disease：The cause of disease of some infectious diseases is this disease
Inducement, such as reticuloendotheliosis, chicken anemia factor, Marek's disease, reovirus, bursa of fabricius diseases.(3) raise
Mismanagement：Hen house temperature, humidity height is unstable and chicken is by other stress factors.
Currently used treatment method has：Start with first from reinforcement feeding management, improvement feeding environment, next to that using medicine
Thing is treated in all directions, such as antiphlogistic, preventing and treating gastric ulcer enhancing peristole class medicine, takes off the mould medicine that heals.Prior art
Preventing and treating ventriculitis has certain effect, but drug cost is larger, treatment cycle is longer, and human input is more, and input-output ratio is still not
It is highly desirable.
In consideration of it, the present invention is special to provide a kind of gravel for treating birds ventriculitis and preparation method thereof.Mainly for birds
Ventriculitis is carried out to because of complex treatment to the ill, being stranded to more comprehensively efficiently solve disease on the whole for what animal body was brought
Disturb.Gravel provided by the invention can retain 3-7 days in muscular stomach, help grate foods and it is preferably digested and assimilated, and mend
Fill calcareous, while gastric acid secretion can be adjusted, kill or suppress mould breeding, can effectively prevent and treat the generation of ventriculitis.It prepares work
Skill is simple, quality controllable, is suitable for industrialized large-scaled production, and is with a wide range of applications.
The content of the invention
It is an object of the invention to provide a kind of gravel for treating birds ventriculitis and preparation method thereof, it is characterised in that：
Described gravel is made up of calcium silicates 30g-70g, calcium carbonate 30g-70g, Amoxicillin 0.25g-1.0g, de- mould dose of 0.5g-1g.
Described de- mould dose selected from clay adsorber, yeast cell wall extract, enzymolysis detoxicant, Chinese herbal medicine class extract etc.
One or both of more than composition.
The clay adsorber is selected from composition more than one or both of montmorillonite, activated carbon, zeolite etc..
The Chinese herbal medicine class extract selects more than one or both of extracts such as Verbena officinalis, adder-wort, kuh-seng, Herba Andrographitis
Composition.
Described a kind of gravel for treating birds ventriculitis and preparation method thereof, it is characterised in that：
The preparation method of the gravel is：
(1) supplementary material is crossed into 80 mesh sieves respectively, claims supplementary material by recipe quantity, it is standby.
(2) calcium silicates, calcium carbonate, Amoxicillin, de- mould dose plus water is taken to prepare softwood.
(3) it is softwood is moulding, it dry, pulverize, whole grain to particle diameter size is 1-5mm.
(4) middle product examine is surveyed, examines character, granularity, mobility, loss on drying, relevant material, content etc., take inspection
Qualified products are packed, and produce a kind of gravel for treating birds ventriculitis.
The beneficial effects of the invention are as follows：
Present invention is generally directed to birds ventriculitis to be carried out to because of complex treatment to the ill, on the whole more comprehensively effectively
It is the puzzlement that animal body is brought to solve disease.Gravel provided by the invention can retain 3-7 days in muscular stomach, help grate foods simultaneously
It is set preferably to digest and assimilate, and supplement calcium, while gastric acid secretion can be adjusted, kill or suppress mould breeding, can effectively prevent
Control the generation of proventriculitis.Its preparation technology is simple, quality controllable, is suitable for industrialized large-scaled production, and is with a wide range of applications.
Embodiment
Following examples are now provided to further explain the present invention, but are not meant to that embodiment is appointed to the present invention
The restriction of what form, all technologies realized based on content of the present invention belong to the scope of the present invention.
Embodiment 1：A kind of preparation for the gravel for treating birds ventriculitis
Prescription one：
| Supplementary material title | Recipe quantity |
| Calcium silicates | 30g |
| Calcium carbonate | 30g |
| Amoxicillin | 1.0g |
| Montmorillonite | 0.5g |
| Water | In right amount |
Preparation method：
(1) supplementary material is crossed into 80 mesh sieves respectively, claims supplementary material by recipe quantity, it is standby.
(2) calcium silicates, calcium carbonate, Amoxicillin, montmorillonite is taken to add water to prepare softwood.
(3) it is softwood is moulding, it dry, pulverize, whole grain to particle diameter size is 1mm.
(4) middle product examine is surveyed, examines character, granularity, mobility, loss on drying, relevant material, content etc., take inspection
Qualified products are packed, and produce a kind of gravel for treating birds ventriculitis.
Embodiment 2：A kind of preparation for the gravel for treating birds ventriculitis
Prescription two：
| Supplementary material title | Recipe quantity |
| Calcium silicates | 50g |
| Calcium carbonate | 50g |
| Amoxicillin | 0.5g |
| Yeast cell wall extract | 0.75g |
| Water | In right amount |
Preparation method：
(1) supplementary material is crossed into 80 mesh sieves respectively, claims supplementary material by recipe quantity, it is standby.
(2) calcium silicates, calcium carbonate, Amoxicillin, yeast cell wall extract is taken to add water to prepare softwood.
(3) it is softwood is moulding, it dry, pulverize, whole grain to particle diameter size is 3mm.
(4) middle product examine is surveyed, examines character, granularity, mobility, loss on drying, relevant material, content etc., take inspection
Qualified products are packed, and produce a kind of gravel for treating birds ventriculitis.
Embodiment 3：A kind of preparation for the gravel for treating birds ventriculitis
Prescription three：
| Supplementary material title | Recipe quantity |
| Calcium silicates | 70g |
| Calcium carbonate | 70g |
| Amoxicillin | 0.25g |
| Andrographis Paniculata | 1g |
| Water | In right amount |
Preparation method：
(1) supplementary material is crossed into 80 mesh sieves respectively, claims supplementary material by recipe quantity, it is standby.
(2) calcium silicates, calcium carbonate, Amoxicillin, Andrographis Paniculata is taken to add water to prepare softwood.
(3) it is softwood is moulding, it dry, pulverize, whole grain to particle diameter size is 5mm.
(4) middle product examine is surveyed, examines character, granularity, mobility, loss on drying, relevant material, content etc., take inspection
Qualified products are packed, and produce a kind of gravel for treating birds ventriculitis.
Embodiment 4：Clinical test
(1) animal packet and administrations
Tested for the chicken house of clinical outburst ventriculitis disease.20000 white meat-type chickens (15 ages in days or so), make a definite diagnosis
Fallen ill for ventriculitis, the incidence of disease is more than 25%.Chicken group is randomly divided into 4 groups, is isolated with column net, every group 5000.First group of feeding
A kind of gravel for treating birds ventriculitis described in prescription two, feeding is mixed thoroughly in 3% ratio in feed in embodiment two；Second
Group feeding Amoxicillin, feeding is mixed thoroughly in 14.8mg/kg ratio in feed；3rd group of feeding weight ratio is 1:1 carbonic acid
The mixture of calcium and calcium silicates, feeding is mixed thoroughly in feed in 3% ratio；4th group is not added other components, Direct-fed
Conventional feed.Continuously fed 7 days by above-mentioned dosage regimen.
(2) efficacy determination and performance assessment criteria
After experiment 7 days, the sample that each group extracts 5% carries out cut open inspection, observes the ventriculitis incidence of disease and situations such as cure rate.
(3) result
A kind of gravel for treating birds ventriculitis described in prescription two in embodiment two is fed, in 3% ratio in feed
Mix feeding thoroughly, the cure rate to ventriculitis is 93.8%, and curative effect is significantly higher than other each groups.As a result see the table below.
The ventriculitis cure rate situation of table 1：
Claims (5)
- A kind of 1. gravel for treating birds ventriculitis, it is characterised in that：The gravel is by calcium silicates 30g-70g, calcium carbonate 30g- 70g, Amoxicillin 0.25g-1.0g, de- mould dose of 0.5g-1g compositions.
- A kind of 2. gravel for treating birds ventriculitis according to claim 1, it is characterised in that：Described de- mould dose is clay Composition more than one or both of adsorbent, yeast cell wall, enzymolysis detoxicant, Chinese herbal medicine class extract etc..
- A kind of 3. gravel for treating birds ventriculitis according to claim 2, it is characterised in that：The clay adsorber is Composition more than one or both of montmorillonite, activated carbon, zeolite etc..
- A kind of 4. gravel for treating birds ventriculitis stated according to claim 2, it is characterised in that：The Chinese herbal medicine class extract Select composition more than one or both of extracts such as Verbena officinalis, adder-wort, kuh-seng, Herba Andrographitis.
- A kind of 5. gravel for treating birds ventriculitis according to claim 1-4, it is characterised in that：The preparation of the gravel Method is：(1) supplementary material is crossed into 80 mesh sieves respectively, claims supplementary material by recipe quantity, it is standby.(2) calcium silicates, calcium carbonate, Amoxicillin, de- mould dose plus water is taken to prepare softwood.(3) it is softwood is moulding, it dry, pulverize, whole grain to particle diameter size is 1-5mm.(4) middle product examine is surveyed, examines character, granularity, mobility, loss on drying, relevant material, content etc., take inspection qualified Product is packed, and produces a kind of gravel for treating birds ventriculitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610782840.7A CN107789362A (en) | 2016-08-31 | 2016-08-31 | A kind of gravel for treating birds ventriculitis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610782840.7A CN107789362A (en) | 2016-08-31 | 2016-08-31 | A kind of gravel for treating birds ventriculitis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107789362A true CN107789362A (en) | 2018-03-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610782840.7A Pending CN107789362A (en) | 2016-08-31 | 2016-08-31 | A kind of gravel for treating birds ventriculitis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107789362A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491292A (en) * | 2008-01-23 | 2009-07-29 | 北京因科瑞斯医药科技有限公司 | Natural feed additive and preparation method thereof |
| CN102078371A (en) * | 2009-11-27 | 2011-06-01 | 天津瑞普生物技术股份有限公司 | Pharmaceutical composition for preventing and treating chicken proventriculitis |
| CN104208089A (en) * | 2014-09-05 | 2014-12-17 | 河南亚卫动物药业有限公司 | Gastric floating preparation for treating poultry proventriculitis and preparation method thereof |
-
2016
- 2016-08-31 CN CN201610782840.7A patent/CN107789362A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491292A (en) * | 2008-01-23 | 2009-07-29 | 北京因科瑞斯医药科技有限公司 | Natural feed additive and preparation method thereof |
| CN102078371A (en) * | 2009-11-27 | 2011-06-01 | 天津瑞普生物技术股份有限公司 | Pharmaceutical composition for preventing and treating chicken proventriculitis |
| CN104208089A (en) * | 2014-09-05 | 2014-12-17 | 河南亚卫动物药业有限公司 | Gastric floating preparation for treating poultry proventriculitis and preparation method thereof |
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| PB01 | Publication | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180313 |
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