CN113907185A - Fermented Chinese herbal medicine additive and preparation method and application thereof - Google Patents

Fermented Chinese herbal medicine additive and preparation method and application thereof Download PDF

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Publication number
CN113907185A
CN113907185A CN202111194283.4A CN202111194283A CN113907185A CN 113907185 A CN113907185 A CN 113907185A CN 202111194283 A CN202111194283 A CN 202111194283A CN 113907185 A CN113907185 A CN 113907185A
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parts
chinese herbal
herbal medicine
liquid
fermented
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李静
李磊
贺绍君
刘德义
王炬
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Anhui University of Science and Technology
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Anhui University of Science and Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/24Compounds of alkaline earth metals, e.g. magnesium
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The invention discloses a fermented Chinese herbal medicine additive and a preparation method and application thereof, belonging to the technical field of feed additives. The fermented Chinese herbal medicine additive is prepared from Chinese herbal medicine raw materials, water and mixed bacterial liquid; the mixed bacterial liquid is bacillus bacterial liquidAnd yeast liquid; the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid to the saccharomycete liquid OD600Are all 0.7; the Chinese herbal medicine raw materials comprise the following components in parts by weight: 8-15 parts of eucommia ulmoides, 8-15 parts of bighead atractylodes rhizome, 10-15 parts of epimedium herb, 30-40 parts of cyrtomium rhizome, 20-25 parts of figwort root, 10-15 parts of hawthorn and 5-10 parts of rice sprout; the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1-1.5; the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g:0.02-0.04 ml; the fermented Chinese herbal medicine additive improves immunity and production capacity of poultry, and improves palatability of feed.

Description

Fermented Chinese herbal medicine additive and preparation method and application thereof
Technical Field
The invention relates to the technical field of feed additives, in particular to a fermented Chinese herbal medicine additive and a preparation method and application thereof.
Background
Along with the gradual expansion of the scale of the breeding industry, the use amount of antibiotics and the like as feed additives is gradually increased, and along with the long-term use of the antibiotics, the harm of the antibiotics to animals and human beings is increasingly highlighted. The intake of a large amount of antibiotics reduces the immunity of the animal body, pathogenic bacteria cause more serious harm in a false way, and the long-term use of a large amount of antibiotics can cause the dysbacteriosis in the intestinal tract of the animal and destroy the micro-ecological environment; the occurrence of drug-resistant bacteria can be induced by long-term use of antibiotics, so that the treatment difficulty is increased, the death rate of animals is high, and the development of the breeding industry is not facilitated; in addition, the drug-resistant bacteria can be directly or indirectly transferred to human beings, for example, antibiotics used by animals are discharged in the form of original forms or metabolites through excrement, remain in the environment, bring adverse effects to ecological environments such as soil environment, surface water body and the like, generate toxic action to the ecological environments through food chains, are finally collected to human bodies through various ways, and finally bring harm to the human bodies.
The use of antibiotics in animal breeding not only harms the health of animals and human beings but also seriously damages the ecological environment, so that a feed additive needs to be found and applied to poultry feed.
Disclosure of Invention
The invention provides a fermented Chinese herbal medicine additive, a preparation method and application thereof, which improve the immunity and the production capacity of poultry and the palatability of feed.
The first purpose of the invention is to provide a fermented Chinese herbal medicine additiveThe additive is prepared from Chinese herbal medicine raw materials, water and mixed bacteria liquid; the mixed bacterial liquid consists of bacillus liquid and saccharomycete liquid; the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid to the saccharomycete liquid OD600Are all 0.7;
the Chinese herbal medicine raw materials comprise the following components in parts by weight: 8-15 parts of eucommia ulmoides, 8-15 parts of bighead atractylodes rhizome, 10-15 parts of epimedium herb, 30-40 parts of cyrtomium rhizome, 20-25 parts of figwort root, 10-15 parts of hawthorn and 5-10 parts of rice sprout;
the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1-1.5;
the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g:0.02-0.04 ml.
Preferably, the Chinese herbal medicine raw materials consist of the following components in parts by weight: 8-12 parts of eucommia ulmoides, 10-15 parts of bighead atractylodes rhizome, 12-15 parts of epimedium herb, 35-40 parts of cyrtomium rhizome, 20-22 parts of figwort root, 12-15 parts of hawthorn and 5-7 parts of rice sprout;
the second purpose of the invention is to provide a preparation method of the fermented Chinese herbal medicine additive, which comprises the following steps:
step 1, weighing eucommia ulmoides, bighead atractylodes rhizome, epimedium herb, cyrtomium rhizome, figwort root, hawthorn and rice sprout according to a proportion, mixing, crushing and sieving to obtain Chinese herbal medicine powder;
step 2, uniformly stirring the Chinese herbal medicine powder and water, adding a mixed bacterial liquid, uniformly mixing, and carrying out anaerobic fermentation for 3-5 days to obtain fermented Chinese herbal medicine;
and 3, drying the fermented Chinese herbal medicine to obtain the fermented Chinese herbal medicine additive.
Preferably, in step 2, the fermentation temperature is 33-34 ℃.
Preferably, in step 3, the drying temperature is 50-60 ℃.
The third purpose of the invention is to provide the application of the fermented Chinese herbal medicine additive in poultry feed, wherein the poultry feed comprises the following components in parts by weight: 60-70 parts of corn, 15-20 parts of soybean meal, 20-27 parts of wheat, 4-8 parts of kelp, 5-10 parts of alfalfa, 1-3 parts of fermented Chinese herbal medicine additive, 2-3 parts of montmorillonite and 1-3 parts of compound vitamin.
Preferably, the compound vitamin consists of equal amounts of vitamin A, vitamin C and vitamin E.
Compared with the prior art, the invention has the following beneficial effects:
(1) the fermented Chinese herbal medicine additive is prepared in a fermentation mode, so that the bitter taste of Chinese herbal medicines is covered, the palatability of medicines is improved, and the digestion of feed is promoted;
(2) the fermented Chinese herbal medicine additive replaces antibiotics, so that the immunity and the production capacity of poultry are improved; the rhizoma Osmundae and radix scrophulariae have effects of preventing and treating common cold, and also have antibacterial effect, and the fructus oryzae contains abundant nutritional substances such as protease, vitamin A, B, starch and protein. The rice sprout is beneficial to protein digestion, can digest and stimulate appetite, and promotes the appetite; the hawthorn can improve the digestibility of protein and fat in the feed, reduce the feed consumption, reduce the occurrence of chicken gastrointestinal bacterial infectious diseases and improve the survival rate, and the hawthorn and the rice sprout have the functions of promoting digestion and invigorating stomach and prevent dyspepsia; the eucommia bark, the white atractylodes rhizome and the epimedium herb can improve the immunity of the poultry in different degrees, and the eucommia bark can also improve the production capacity of the poultry.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The bacillus used in the invention is bacillus licheniformis, and the preservation number is CGMCC No. 5094. Purchased from China center for culture Collection of microorganisms, the yeast is Saccharomyces rouxii with the preservation number: CGMCC No.2.371, purchased from China general microbiological culture Collection center.
The culture method of the bacillus liquid refers to the research on the optimization of the components of the bacillus subtilis liquid fermentation culture medium published by Jufei, vol.45, No. 18 of 2017, Guangzhou chemical engineering.
The culture method of the yeast liquid refers to 'composition optimization of a yeast liquid culture medium for production', published by Luchunfang and the like in No. 8 of volume 26 of animal nutrition bulletin 2014.
Example 1
The embodiment provides a fermented Chinese herbal medicine additive, which is prepared from Chinese herbal medicine raw materials, water and a mixed bacterium solution;
the Chinese herbal medicine raw materials comprise the following components in parts by weight: 150g of eucommia ulmoides, 100g of bighead atractylodes rhizome, 150g of epimedium herb, 300g of cyrtomium rhizome, 200g of figwort root, 120g of hawthorn and 50g of rice sprout;
the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1.2;
the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g to 0.03 ml.
The mixed bacterial liquid consists of bacillus liquid and saccharomycete liquid; the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid to the saccharomycete liquid OD600Are all 0.7.
The embodiment also provides a preparation method of the fermented Chinese herbal medicine additive, which comprises the following steps:
step 1, weighing eucommia ulmoides, bighead atractylodes rhizome, epimedium herb, cyrtomium rhizome, figwort root, hawthorn and rice sprout according to a proportion, mixing, crushing and sieving with a 40-mesh sieve to obtain Chinese herbal medicine powder;
step 2, uniformly stirring the Chinese herbal medicine powder and water, adding a mixed bacterial liquid, uniformly mixing, and performing anaerobic fermentation at 33 ℃ for 3 days to obtain fermented Chinese herbal medicine;
and 3, drying the fermented Chinese herbal medicines at 50 ℃ to obtain the fermented Chinese herbal medicine additive.
Example 2
The embodiment provides a fermented Chinese herbal medicine additive, which is prepared from Chinese herbal medicine raw materials, water and a mixed bacterium solution;
the Chinese herbal medicine raw materials comprise the following components in parts by weight: 80g of eucommia bark, 150g of bighead atractylodes rhizome, 130g of epimedium herb, 400g of cyrtomium rhizome, 250g of figwort root, 100g of hawthorn fruit and 70g of rice sprout;
the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1.2;
the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g to 0.03 ml.
The mixed bacterial liquid consists of bacillus liquid and saccharomycete liquid; the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid to the saccharomycete liquid OD600Are all 0.7.
The embodiment also provides a preparation method of the fermented Chinese herbal medicine additive, which comprises the following steps:
step 1, weighing eucommia ulmoides, bighead atractylodes rhizome, epimedium herb, cyrtomium rhizome, figwort root, hawthorn and rice sprout according to a proportion, mixing, crushing and sieving with a 40-mesh sieve to obtain Chinese herbal medicine powder;
step 2, uniformly stirring the Chinese herbal medicine powder and water, adding a mixed bacterial liquid, uniformly mixing, and performing anaerobic fermentation at 33 ℃ for 3 days to obtain fermented Chinese herbal medicine;
and 3, drying the fermented Chinese herbal medicines at 50 ℃ to obtain the fermented Chinese herbal medicine additive.
Example 3
The embodiment provides a fermented Chinese herbal medicine additive, which is prepared from Chinese herbal medicine raw materials, water and a mixed bacterium solution;
the Chinese herbal medicine raw materials comprise the following components in parts by weight: 120g of eucommia ulmoides, 80g of bighead atractylodes rhizome, 100g of epimedium herb, 350g of cyrtomium rhizome, 220g of figwort root, 150g of hawthorn and 100g of rice sprout;
the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1;
the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g:0.02 ml.
The mixed bacterial liquid consists of bacillus liquid and saccharomycete liquid; the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid to the saccharomycete liquid OD600Are all 0.7
The embodiment also provides a preparation method of the fermented Chinese herbal medicine additive, which comprises the following steps:
step 1, weighing eucommia ulmoides, bighead atractylodes rhizome, epimedium herb, cyrtomium rhizome, figwort root, hawthorn and rice sprout according to a proportion, mixing, crushing and sieving with a 40-mesh sieve to obtain Chinese herbal medicine powder;
step 2, uniformly stirring the Chinese herbal medicine powder and water, adding a mixed bacterial liquid, uniformly mixing, and performing anaerobic fermentation at 34 ℃ for 4 days to obtain fermented Chinese herbal medicine;
and 3, drying the fermented Chinese herbal medicines at 60 ℃ to obtain the fermented Chinese herbal medicine additive.
Example 4
The embodiment provides a fermented Chinese herbal medicine additive, which is prepared from Chinese herbal medicine raw materials, water and a mixed bacterium solution;
the Chinese herbal medicine raw materials comprise the following components in parts by weight: 100g of eucommia ulmoides, 120g of bighead atractylodes rhizome, 120g of epimedium herb, 370g of cyrtomium rhizome, 210g of figwort root, 140g of hawthorn and 650g of rice sprout;
the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1.5;
the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g:0.04 ml.
The mixed bacterial liquid consists of bacillus liquid and saccharomycete liquid; the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid to the saccharomycete liquid OD600Are all 0.7.
The embodiment also provides a preparation method of the fermented Chinese herbal medicine additive, which comprises the following steps:
step 1, weighing eucommia ulmoides, bighead atractylodes rhizome, epimedium herb, cyrtomium rhizome, figwort root, hawthorn and rice sprout according to a proportion, mixing, crushing and sieving with a 40-mesh sieve to obtain Chinese herbal medicine powder;
step 2, uniformly stirring the Chinese herbal medicine powder and water, adding a mixed bacterial liquid, uniformly mixing, and performing anaerobic fermentation at 34 ℃ for 5 days to obtain fermented Chinese herbal medicine;
and 3, drying the fermented Chinese herbal medicines at 55 ℃ to obtain the fermented Chinese herbal medicine additive.
Example 5
The embodiment provides an application of a Chinese herbal medicine additive in poultry feed, and the poultry feed comprises the following components in parts by weight: 600g of corn, 200g of bean pulp, 270g of wheat, 40g of kelp, 100g of alfalfa, 30g of fermented Chinese herbal medicine additive, 30g of montmorillonite and 1 part of compound vitamin; the compound vitamin comprises equal amounts of vitamin A, vitamin C and vitamin E. The fermented herbal medicine additive added in this example was prepared according to the preparation method of example 2.
Example 6
The embodiment provides an application of a Chinese herbal medicine additive in poultry feed, and the poultry feed comprises the following components in parts by weight: 700g of corn, 150g of soybean meal, 200g of wheat, 60g of kelp, 70g of alfalfa, 20g of fermented Chinese herbal medicine additive, 20g of montmorillonite and 30g of compound vitamin; the compound vitamin comprises equal amounts of vitamin A, vitamin C and vitamin E. The fermented herbal medicine additive added in this example was prepared according to the preparation method of example 4.
Example 7
The embodiment provides an application of a Chinese herbal medicine additive in poultry feed, and the poultry feed comprises the following components in parts by weight: 650g of corn, 170g of soybean meal, 240g of wheat, 80g of kelp, 50g of alfalfa, 10g of fermented Chinese herbal medicine additive, 30g of montmorillonite and 20g of compound vitamin; the compound vitamin comprises equal amounts of vitamin A, vitamin C and vitamin E. The fermented herbal medicine additive added in this example was prepared according to the preparation method of example 4.
Comparative example 1
This comparative example is a commercial feed.
Comparative example 2
The comparative example is a commercial feed added with the fermented Chinese herbal medicine additive prepared in example 4, and the ratio of the feed to the fermented Chinese herbal medicine additive is the same as that of the feed to the Chinese herbal medicine additive in example 6.
Comparative example 3
The poultry feed of this comparative example was the same as the feed of example 6 except that no fermented herbal additive was added in this comparative example.
Comparative example 4
The poultry feed of this comparative example was the same as the feed of example 6 except that the Chinese herbal medicine additive was added in this comparative example and treated according to step 1 of example 4 without fermentation treatment.
Laying hens with basically identical physique and 20 days old are selected to be divided into 7 groups, each group comprises 80 laying hens, the laying hens are fed according to the poultry feeds of the examples 5-7 and the comparative examples 1-2, the feeding times, the feeding amount and the feeding time are communicated each other every day, the laying hens feed freely and drink water freely, and the recorded results are shown in tables 1-3.
TABLE 1 production Performance of layers
Group of Poultry feed Onset (d) Egg production period (d) Laying rate (%)
1 Example 5 141 443 89.1
2 Example 6 137 450 89.9
3 Practice ofExample 7 140 447 89.3
4 Comparative example 1 148 427 83.7
5 Comparative example 2 145 436 85.9
As can be seen from Table 1, the feed prepared in examples 5 to 7 advanced the laying period, extended the laying period, and increased the laying rate. Taking example 6 as an example, the laying period is 137 days, the laying period is 450 days, the laying rate is up to 89.9%, compared with comparative examples 1-2, the laying period is advanced by 8-11 days, the laying period is prolonged by 14-23 days, and the laying rate is improved by 4-6.2%.
TABLE 2 average daily feed intake of layers
Figure BDA0003302433260000071
Figure BDA0003302433260000081
As can be seen from Table 2, the average daily intake of the laying hens was increased by fermenting the Chinese herbal medicines when preparing the fermented Chinese herbal medicine additive. The original bitter taste of the Chinese herbal medicines can be covered after the fermentation treatment, and the feed intake is effectively improved and the palatability of the feed is improved after the Chinese herbal medicines are added into the feed.
TABLE 3 incidence of layer chicken
Group of Poultry feed Incidence (%)
1 Example 5 4.34
2 Example 6 4.33
3 Example 7 4.33
4 Comparative example 1 7.31
4 Comparative example 3 5.91
Statistics of incidence: the sick chicken takes the excrement of the observed chicken as the feed excrement and the poor spirit as the standard; healthy chickens feed normally, have normal spirit and have normal defecation. As can be seen from table 3, the feeds prepared in examples 5 to 7 effectively reduced the incidence of laying hens by about 2.98% compared to comparative example 1 and by 1.58% compared to comparative example 4. The immunity of the laying hens is improved.
While preferred embodiments of the present invention have been described, additional variations and modifications in those embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (7)

1. A fermented Chinese herbal medicine additive is characterized in that the fermented Chinese herbal medicine additive is prepared from Chinese herbal medicine raw materials, water and mixed bacterial liquid; the mixed bacterial liquid consists of bacillus liquid and saccharomycete liquid, the volume ratio of the bacillus liquid to the saccharomycete liquid is 1:1, and the bacillus liquid and the saccharomycete liquid OD600Are all 0.7;
the Chinese herbal medicine raw materials comprise the following components in parts by weight: 8-15 parts of eucommia ulmoides, 8-15 parts of bighead atractylodes rhizome, 10-15 parts of epimedium herb, 30-40 parts of cyrtomium rhizome, 20-25 parts of figwort root, 10-15 parts of hawthorn and 5-10 parts of rice sprout;
the mass ratio of the Chinese herbal medicine raw materials to the water is 1: 1-1.5;
the dosage ratio of the Chinese herbal medicine raw materials to the mixed bacterial liquid is 1g:0.02-0.04 ml.
2. The fermented Chinese herbal medicine additive as claimed in claim 1, wherein the Chinese herbal medicine raw materials comprise the following components in parts by weight: 8-12 parts of eucommia ulmoides, 10-15 parts of bighead atractylodes rhizome, 12-15 parts of epimedium herb, 35-40 parts of cyrtomium rhizome, 20-22 parts of figwort root, 12-15 parts of hawthorn fruit and 5-7 parts of rice sprout.
3. A method for preparing the fermented Chinese herbal medicine additive as claimed in claim 1 or 2, which is characterized by comprising the following steps:
step 1, weighing eucommia ulmoides, bighead atractylodes rhizome, epimedium herb, cyrtomium rhizome, figwort root, hawthorn and rice sprout according to a proportion, mixing, crushing and sieving to obtain Chinese herbal medicine powder;
step 2, uniformly stirring the Chinese herbal medicine powder and water, adding a mixed bacterial liquid, uniformly mixing, and carrying out anaerobic fermentation for 3-5 days to obtain fermented Chinese herbal medicine;
and 3, drying the fermented Chinese herbal medicine to obtain the fermented Chinese herbal medicine additive.
4. The method for preparing the fermented Chinese herbal medicine additive as claimed in claim 3, wherein the fermentation temperature in step 2 is 33-34 ℃.
5. The method for preparing the fermented Chinese herbal medicine additive as claimed in claim 3, wherein the drying temperature in step 3 is 50-60 ℃.
6. The use of the fermented Chinese herbal medicine additive as described in claim 1 or 2 in poultry feed, wherein the poultry feed comprises the following components in parts by weight: 60-70 parts of corn, 15-20 parts of soybean meal, 20-27 parts of wheat, 4-8 parts of kelp, 5-10 parts of alfalfa, 1-3 parts of fermented Chinese herbal medicine additive, 2-3 parts of montmorillonite and 1-3 parts of compound vitamin.
7. The use of the fermented herbal additive in poultry feed according to claim 6, wherein the vitamin complex consists of equal amounts of vitamin A, vitamin C, vitamin E.
CN202111194283.4A 2021-10-13 2021-10-13 Fermented Chinese herbal medicine additive and preparation method and application thereof Pending CN113907185A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114601075A (en) * 2022-04-17 2022-06-10 湖南省吉泰农牧股份有限公司 Anti-stress laying hen feed containing Chinese herbal medicines and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104161206A (en) * 2013-07-17 2014-11-26 河南联合英伟饲料有限公司 Feed additive for increasing egg yield of hens and preparation method thereof
CN104719666A (en) * 2015-02-27 2015-06-24 河南科技大学 Special fermented Chinese herbal medicine feed additive for laying hen and preparation method of special fermented Chinese herbal medicine feed additive

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104161206A (en) * 2013-07-17 2014-11-26 河南联合英伟饲料有限公司 Feed additive for increasing egg yield of hens and preparation method thereof
CN104719666A (en) * 2015-02-27 2015-06-24 河南科技大学 Special fermented Chinese herbal medicine feed additive for laying hen and preparation method of special fermented Chinese herbal medicine feed additive

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114601075A (en) * 2022-04-17 2022-06-10 湖南省吉泰农牧股份有限公司 Anti-stress laying hen feed containing Chinese herbal medicines and preparation method thereof

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