CN107773251A - Closed extraction PRP evacuated blood collection tubes and its supporting apparatus - Google Patents

Closed extraction PRP evacuated blood collection tubes and its supporting apparatus Download PDF

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Publication number
CN107773251A
CN107773251A CN201610729529.6A CN201610729529A CN107773251A CN 107773251 A CN107773251 A CN 107773251A CN 201610729529 A CN201610729529 A CN 201610729529A CN 107773251 A CN107773251 A CN 107773251A
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CN
China
Prior art keywords
tube
blood
pipe
prp
evacuated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610729529.6A
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Chinese (zh)
Inventor
付士明
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Individual
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Individual
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Priority to CN201610729529.6A priority Critical patent/CN107773251A/en
Publication of CN107773251A publication Critical patent/CN107773251A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154Devices using pre-evacuated means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood

Abstract

The present invention is a kind of evacuated blood collection tube, particularly a kind of closed extraction PRP evacuated blood collection tubes and its supporting apparatus.Collection tube is made up of original pipe, plug and protective cap, and plug is encapsulated in the mouth of pipe of former pipe, and outside plug, former pipe is evacuated protective cap bag;The tube wall of former pipe is provided with a tube wall opening, and tube wall opening is closed with tube wall rubber cushion;The bottom of former pipe is provided with blood separating colloid, and anti-coagulants is provided with above blood separating colloid;The supporting apparatus air balance pin, is made up of needle point, needle stand and filter, and needle point is located at needle stand front end, and filter is located at needle stand rear end;The blood anticoagulant includes any one of edta salt, heparin, sodium citrate and its buffer solution or ACD liquid;The functional additive includes sodium hyaluronate or blood separating liquid;The platelet activating agent includes any one or combinations thereof of calcium chloride, fibrin ferment, calcium gluconate or calcium phosphate.Due to mouth of pipe plug need not be opened during extraction PRP, so avoiding the microorganism pollution of operating process.

Description

Closed extraction PRP evacuated blood collection tubes and its supporting apparatus
Technical field
The present invention is a kind of evacuated blood collection tube, particularly a kind of closed extraction PRP evacuated blood collection tubes and its Supporting apparatus.
Background technology
PRP is the english abbreviation of platelet rich plasma(platelet-rich plasma).PRP be widely used in orthopaedics, The fields such as tendon injury, beauty, dentistry, burn.In these fields, PRP needs higher concentration, while must also additionally add Reagent adding, to ensure that PRP discharges more more effective growth factors upon activation, also need to sometimes PRP and other tissue factors, Cell factor or special agents in combination application, to reach more preferable effect.So PRP is correctly safely and effectively extracted, it is heavy to closing Will, this just proposes very high requirement to PRP extraction vessel.
PRP extraction will above all avoid pollution of the environmental microorganism to PRP, due to existing using open Extract, and mixed when being used with other agents in combination using open, so environmental microorganism can not be avoided to PRP Pollution.
The content of the invention
The defects of the invention aims to overcome existing extraction vessel easily to cause PRP to be contaminated, invention are a kind of Closed the extraction PRP evacuated blood collection tubes and its supporting apparatus of microorganism pollution can effectively be reduced.
The purpose of the present invention is realized as follows:
A kind of closed extraction PRP evacuated blood collection tubes, it is made up of original pipe, plug and protective cap, plug is encapsulated in the pipe of former pipe Mouthful, outside plug, former pipe is evacuated protective cap bag;The tube wall of former pipe is provided with a tube wall opening, tube wall opening tube wall glue Pad closing;The bottom of former pipe is provided with blood separating colloid, and anti-coagulants is provided with above blood separating colloid.
Another closed extraction PRP evacuated blood collection tubes, by rubber linking tube, upper tube, down tube, plug and protective cap Composition, plug are encapsulated in the mouth of pipe of upper tube, and protective cap bag is outside plug, and the other end of upper tube is connected with rubber linking tube, rubber The other end of connecting tube is connected with down tube, is formed a stage casing and is the test tube of rubber tube, and is evacuated;The bottom of down tube Provided with blood separating colloid, anti-coagulants is provided with above blood separating colloid.
Another closed extraction PRP evacuated blood collection tube, it is made up of original pipe, plug and protective cap, plug is encapsulated in original The mouth of pipe of pipe, outside plug, former pipe is evacuated protective cap bag;The tube wall of former pipe is provided with a tube wall opening, and tube wall opening is used Tube wall rubber cushion is closed;Former bottom of the tube is from bottom to top respectively equipped with functional additive, blood separating colloid, platelet activating agent, blood Liquid separation gel and blood anticoagulant.
A kind of and matching used utensil air balance pin of closed extraction PRP evacuated blood collection tubes, by needle point, needle stand Formed with filter, needle point is located at needle stand front end, and filter is located at needle stand rear end, and filter was used for air filtering.
The blood anticoagulant includes any one in edta salt, heparin, sodium citrate and its buffer solution or ACD liquid; The functional additive includes sodium hyaluronate or blood separating liquid;The platelet activating agent includes calcium chloride, fibrin ferment, grape Any one in Calciofon or calcium phosphate or combinations thereof.
The blood separating colloid requirement can be resistant to 60Coradiation and unharmful substance migrates.
The former pipe, top tube and down tube are molded by PET material, tube wall rubber cushion and rubber linking tube by butyl rubber or TPE is made.
The needle point is stainless steel or rigid plastics, and needle stand PP, ABS plastic, filter is hole plastics or filter membrane.
The positive effect of the present invention is as follows:Due to mouth of pipe plug need not be opened during extraction PRP, so farthest avoiding The pollution of operating process.
Brief description of the drawings
Fig. 1 is first embodiment structure chart
Fig. 2 is second embodiment structure chart
Fig. 3 is 3rd embodiment structure chart
Fig. 4 is air balance needle construction figure
In figure:The 1 former protective cap of 2 plug of pipe 3
The rubber linking tube of 4 tube wall opening, 5 tube wall rubber cushion 6
The blood separating colloid of 7 upper tube, 8 down tube 9
The platelet activating agent of 10 blood anticoagulant, 11 functional additive 12
The filter of 13 needle point, 14 needle stand 15
Embodiment
A kind of closed extraction PRP evacuated blood collection tubes, are made up of, plug 2 is encapsulated in former pipe 1, plug 2 and protective cap 3 The mouth of pipe of former pipe 1, protective cap 3 wraps to be evacuated in the outside of plug 2, former pipe 1;The tube wall of former pipe 1 is provided with a tube wall opening 4, pipe Wall opening 4 is closed with tube wall rubber cushion 5;The bottom of former pipe 1 is provided with blood separating colloid 9, and blood separating colloid 9 is provided with anti-coagulants above 10。
Another closed extraction PRP evacuated blood collection tubes, by rubber linking tube 6, upper tube 7, down tube 8, plug 2 and protect Helmet 3 is formed, and plug 2 is encapsulated in the mouth of pipe of upper tube 7, and protective cap 3 is wrapped in the outside of plug 2, the other end and rubber linking tube of upper tube 7 6 connections, the other end of rubber linking tube 6 are connected with down tube 8, are formed a stage casing and are the test tube of rubber tube, and are pumped into true It is empty;The bottom of down tube 8 is provided with blood separating colloid 9, and anti-coagulants 10 is provided with above blood separating colloid 9.
Another closed extraction PRP evacuated blood collection tube, is made up of, the envelope of plug 2 former pipe 1, plug 2 and protective cap 3 In the mouth of pipe of former pipe 1, protective cap 3 wraps to be evacuated in the outside of plug 2, former pipe 1;The tube wall of former pipe 1 is provided with a tube wall opening 4, Tube wall opening 4 is closed with tube wall rubber cushion 5;The former bottom of pipe 1 be from bottom to top respectively equipped with functional additive 11, blood separating colloid 9, Platelet activating agent 12, blood separating colloid 9 and blood anticoagulant 10.
A kind of and matching used utensil air balance pin of closed extraction PRP evacuated blood collection tubes, by needle point 13, pin Seat 14 and filter 15 form, and needle point 13 is located at the front end of needle stand 14, and filter 15 is located at the rear end of needle stand 14, and filter is used to filter Air.
The blood anticoagulant 10 is including any one in edta salt, heparin, sodium citrate and its buffer solution or ACD liquid Kind;The functional additive 11 includes sodium hyaluronate or blood separating liquid;The platelet activating agent 12 includes calcium chloride, blood coagulation Any one in enzyme, calcium gluconate, calcium phosphate or combinations thereof.
The requirement of blood separating colloid 9 can be resistant to 60Coradiation and unharmful substance migrates.
The former pipe 1, upper tube 7 and down tube 8 are molded by PET material, and tube wall rubber cushion and rubber linking tube are by butyl rubber Glue or TPE are made.
The needle point 13 is stainless steel or rigid plastics, and needle stand 14 is PP, ABS plastic, filter 15 be hole plastics or Filter membrane.
After blood sampling centrifugation, under the influence of centrifugal force, due to the difference of blood sample composition and separation gel proportion, blood sample is separated Into PRP, PPP (platelet poor plasma) and blood cell, blood cell is located at bottom, and separation gel is located on blood cell, and PRP is predominantly located at point In the range of the 2cm on glue, wherein PRP bottom surface is in the range of tube wall opening, the preferred bottom of PRP bottom surfaces and tube wall opening Support flat or maintain an equal level with the top of down tube, PPP is then on PRP.When extracting PRP, tube wall rubber cushion or rubber are passed through with syringe Gemel connection pipe directly extracts PRP, without opening mouth of pipe plug.Negative pressure is produced during to avoid extracting PRP in pipe, it is necessary to use balancing needle Penetration tube chewing-gum plug or tube wall rubber cushion or rubber linking tube.Similar method can be used by extracting PPP.
Present invention embodiment listed above is more typical example, does not limit the present invention, all to do on the basis of the present invention Improvement, modification and replacement all should include it is within the scope of the present invention.

Claims (9)

  1. A kind of 1. closed extraction PRP evacuated blood collection tubes, it is characterised in that:The tube wall of former pipe is provided with a tube wall opening, pipe Wall opening is closed with tube wall rubber cushion;The bottom of former pipe is provided with blood separating colloid, and anti-coagulants is provided with above blood separating colloid.
  2. A kind of 2. closed extraction PRP evacuated blood collection tubes, it is characterised in that:It is by rubber linking tube, upper tube, down tube, glue Plug and protective cap composition, plug are encapsulated in the mouth of pipe of upper tube, and protective cap bag is outside plug, the other end and rubber linking tube of upper tube Connection, the other end of rubber linking tube are connected with down tube, are formed a stage casing and are the test tube of rubber tube, and are evacuated; The bottom of down tube is provided with blood separating colloid, and anti-coagulants is provided with above blood separating colloid.
  3. A kind of 3. closed extraction PRP evacuated blood collection tubes, it is characterised in that:The tube wall of former pipe is provided with a tube wall opening, pipe Wall opening is closed with tube wall rubber cushion;Former bottom of the tube is from bottom to top respectively equipped with functional additive, blood separating colloid, blood platelet and swashed Agent, blood separating colloid and blood anticoagulant living.
  4. A kind of 4. and matching used utensil air balance pin of closed extraction PRP evacuated blood collection tubes, it is characterised in that:Its It is made up of needle point, needle stand and filter, needle point is located at needle stand front end, and filter is located at needle stand rear end, and filter is used to filter sky Gas.
  5. 5. the closed extraction PRP evacuated blood collection tubes according to claim 1,2 and 3, it is characterised in that:The blood Anti-coagulants includes any one in edta salt, heparin, sodium citrate and its buffer solution or ACD liquid.
  6. 6. closed extraction PRP evacuated blood collection tubes according to claim 3, it is characterised in that:The feature adds Agent is added to include sodium hyaluronate or blood separating liquid;The platelet activating agent includes calcium chloride, fibrin ferment, calcium gluconate or phosphoric acid Any one in calcium or combinations thereof.
  7. 7. the closed extraction PRP evacuated blood collection tubes according to claim 1,2 and 3, it is characterised in that:The blood Separation gel requirement can be resistant to 60Coradiation and unharmful substance migrates.
  8. 8. the closed extraction PRP evacuated blood collection tubes according to claim 1,2 or 3, it is characterised in that:The original Pipe, top tube and down tube are molded by PET material, and tube wall rubber cushion and rubber linking tube are made up of butyl rubber or TPE.
  9. 9. closed extraction PRP evacuated blood collection tubes according to claim 4, it is characterised in that:The needle point is not Rust steel or rigid plastics, needle stand are PP or ABS plastic, and filter is hole plastics or filter membrane.
CN201610729529.6A 2016-08-25 2016-08-25 Closed extraction PRP evacuated blood collection tubes and its supporting apparatus Pending CN107773251A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN201610729529.6A CN107773251A (en) 2016-08-25 2016-08-25 Closed extraction PRP evacuated blood collection tubes and its supporting apparatus

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111110915A (en) * 2020-02-28 2020-05-08 珠海中信大有科技有限公司 Manufacturing method and application of autologous growth factor patch for constructing musculoskeletal tissue

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942191A (en) * 1997-07-14 1999-08-24 Becton, Dickinson And Company Body fluid collection vessel having reduced capacity
US20040223889A1 (en) * 2003-02-03 2004-11-11 Becton, Dickinson And Company Container assembly and method for making assembly
CN201643233U (en) * 2010-03-26 2010-11-24 戴法宝 Medicine dispensing and air discharging needle of disposable transfusion bottle
CN203169690U (en) * 2013-04-01 2013-09-04 浙江康慈医疗科技有限公司 Special equipment for quickly extracting platelet-rich and high-concentration plasma
CN103750847A (en) * 2014-01-10 2014-04-30 付士明 Collecting container for mononuclear cells and platelet-rich plasma
CN204636389U (en) * 2015-05-08 2015-09-16 长沙郝怡雅医药科技有限公司 A kind of novel evacuated blood taking tube

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942191A (en) * 1997-07-14 1999-08-24 Becton, Dickinson And Company Body fluid collection vessel having reduced capacity
US20040223889A1 (en) * 2003-02-03 2004-11-11 Becton, Dickinson And Company Container assembly and method for making assembly
CN201643233U (en) * 2010-03-26 2010-11-24 戴法宝 Medicine dispensing and air discharging needle of disposable transfusion bottle
CN203169690U (en) * 2013-04-01 2013-09-04 浙江康慈医疗科技有限公司 Special equipment for quickly extracting platelet-rich and high-concentration plasma
CN103750847A (en) * 2014-01-10 2014-04-30 付士明 Collecting container for mononuclear cells and platelet-rich plasma
CN204636389U (en) * 2015-05-08 2015-09-16 长沙郝怡雅医药科技有限公司 A kind of novel evacuated blood taking tube

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111110915A (en) * 2020-02-28 2020-05-08 珠海中信大有科技有限公司 Manufacturing method and application of autologous growth factor patch for constructing musculoskeletal tissue

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Application publication date: 20180309

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