Serum and haemocyte separator tube
Technical field
The utility model relates to a kind of medical apparatus, relates in particular to a kind of clinical examination process that is used for, the separator tube that the serum in the blood is separated with haemocyte.
Background technology
At present, separation of serum all adopts the identical cuvette of diameter up and down with haemocyte.Separated plasma to be adopted and adds behind the anti-coagulants way of centrifugation again, blood plasma is separated with haemocyte, but it is muddy easily when getting blood plasma, separate not thorough, blood sample long slightly back standing time is haemolysis easily, if when adopting the automatic analyzer analysed for plasma, the easy blocking pipe of unprecipitated haemocyte, blood plasma must take out and can store.Separation of serum adopts after the blood natural coagulation method of centrifugation more more, when taking out serum and analyze, has a muddy easily problem equally.
In addition, Japanese patent application publication No. Sho 51-83654 discloses a kind of blood testing container, has wherein contained thixotroping serum or plasma separation compositions in the blood collection tube bottom, for example, and the mixture of siloxanes and silica.Blood is collected in the blood collection tube, places reasonable time and centrifugal.Then, gluey serum or plasma separation compositions becomes and can flow under centrifugal action.Simultaneously, the proportion of gluey serum or plasma separation compositions is between serum or plasma component (proportion about 1.02) and blood clot or cellular component (proportion about 1.08) (1.03-1.07).Therefore, isolate compositions floats gradually from the bottom of pipe in collecting blood, and is positioned between serum or plasma layer and blood clot or the cellular layer, to determine successfully separating that serum or plasma fraction separate from blood clot or cellular component.At this moment can from blood collection tube, tell at an easy rate from the serum or the plasma fraction of blood or cellular component separation, carry out various detections.Also can not need transfer to other container storage.But such thixotroping serum or plasma separation compositions can contain the main component except that mentioned component.For example, isolate compositions has advised also containing the reagent of oligomer and adjusting proportion, viscosity and/or thixotropic nature except that containing aforementioned siloxanes.The example of oligomer comprises: halogenated hydrocarbon oligomer, acrylate oligomer, ester oligomer and cyclic hydrocarbon oligomer.The example of conditioning agent comprises inorganic particle such as silica and kaolin and organic gel agent such as benzylidene sorbitol.Yet aforementioned organic siliconresin shows compatibility obviously poor and proportion that be made up of inorganic particle and viscosity modifier, and extremely sensitive to being separated at short notice.Curing reaction takes place when equally, organic siliconresin carries out irradiation-sterilize.Therefore, the organic siliconresin there be limited evidence currently of uses.And the halogenated hydrocarbon oligomer when burning disposal, produces hydrogen halide, and it may cause damage or environment is caused harmful effect incinerator.Each contains a lot of polar groups in molecule for aforementioned acrylate oligomer and ester oligomer, and having when detecting blood concentration increases the problem that drug absorption takes place.
The utility model content
The purpose of this utility model is to overcome the problems referred to above of the separator existence that in the prior art serum in the blood is separated with haemocyte, and a kind of serum and haemocyte separator tube are provided.The utility model can thoroughly separate the serum in the blood with haemocyte, and can not produce turbid phenomenon when extracting, and isolated serum is through the long-time viscosity no change of placing, and serum and haemocyte do not mix through slightly waving yet.
For achieving the above object, the technical solution adopted in the utility model is as follows:
A kind of serum and haemocyte separator tube, comprise transparent tube body and the sealing-plug that cooperates with body, it is characterized in that: the diameter of described body cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis is 1.5 degree, one 1.8 degree, and release agent is housed in the body.
Described sealing-plug is a rubber stopper, and the rubber stopper cross section is " protruding " shape, protruding end and body fitted seal.
Be snapped with splash cap on the described sealing-plug.
Adopt advantage of the present utility model to be:
One, the utility model can thoroughly separate the serum in the blood with haemocyte, and can not produce turbid phenomenon when extracting, the angle that adopts tube body wall and vertical axis is 1.5 degree-1.8 degree, make isolated serum through the long-time viscosity no change of placing, serum and haemocyte do not mix through slightly waving yet.
Two, the utility model has overcome the defective of existing separation of serum or the existence of haemocyte utensil, the efficient and the effect of blood sample analysis are improved greatly, utilize this disposable minute blood test tube, jam-pack rubber stopper behind the branch blood, blood plasma or serum can be stayed in vitro and store, save the storage utensil, simplified the storage means.
Three, the utility model sealing-plug is a rubber stopper, and rubber stopper is " protruding " shape, and protruding end and body fitted seal can be stayed in vitro blood plasma or serum for a long time and stored.
Four, adopt the separator tube of serum of the present utility model and haemocyte, preparation technology is simple, and raw material is easy to get, and cost is low, and environmentally safe.
Description of drawings
Fig. 1 is the utility model structural representation
Fig. 2 adds schematic diagram behind the glue for the utility model
Fig. 3 is the utility model blood sampling back schematic diagram
Fig. 4 is the centrifugal back of a utility model schematic diagram
Be labeled as among the figure: 1, body, 2, sealing-plug, 3, splash cap, 4, release agent, 5, blood, 6, serum, 7, vertical axis, 8, haemocyte.
The specific embodiment
Embodiment 1
A kind of serum and haemocyte separator tube comprise transparent tube body 1 and the sealing-plug 2 that cooperates with body 1, and the diameter of body 1 cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis 7 is 1.5 degree, and release agent 4 is housed in the body 1.Wherein, sealing-plug 2 is a rubber stopper, and the rubber stopper cross section is " protruding " shape, protruding end and body 1 fitted seal.On sealing-plug, be snapped with splash cap 3.
Body material in the utility model is not particularly limited.The example of material comprises, thermoplastic resin, as, polyethylene, polypropylene, polystyrene, PET, polymethyl methacrylate, polyacrylonitrile, polyamide, acrylonitrile.Styrol copolymer and ethene. ethenol copolymer; Thermosetting resin, as, undersaturated polyester, epoxy and epoxy acrylate resin; The natural resin of modification, as, cellulose ethanoate, cellulose propionate, ethyl cellulose, ethyl chitin; Silicate glass, as, soda-soda lime glass, phosphoric acid silicate glass and borosilicate glass; Glass is fused silica for example.The material of listing above both can they be used in combination also and can be used in combination with other secondary materials.Also can use conventional in the prior art known other materials.
The release agent that adopts in the utility model can be made up of the material of following weight:
Macromolecular hydrocarbon 50-85 part; Hydrophobic silica 15-30 part; Its proportion is 1.04-1.05 for 20 ℃, and viscosity is 20 * 10 for 20 ℃
4-60 * 10
4Cp.
Macromolecular hydrocarbon can be one or more in polybutadiene, polyisobutene, atoleine, the polyglyceryl ether.
Operation principle of the present utility model is as follows:
The blood 5 that injects separator tube can make blood anticoagulant as required or be rapidly solidificated into clot, shrink fast, when centrifugation, at the ask separation layer that form a semisolid of serum 6, when extracting blood plasma or serum with haemocyte 8, because this separation layer is arranged, and the test tube diameter is up big and down small, in the middle of separation layer floats over, the two is isolated well, guaranteed not produce turbid phenomenon, made the separation of blood plasma or serum very thorough.
Embodiment 2
A kind of serum and haemocyte separator tube comprise transparent tube body 1 and the sealing-plug 2 that cooperates with body 1, and the diameter of body 1 cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis 7 is 1.6 degree, and release agent 4 is housed in the body 1.
Embodiment 3
A kind of serum and haemocyte separator tube comprise transparent tube body 1 and the sealing-plug 2 that cooperates with body 1, and the diameter of body 1 cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis 7 is 1.8 degree, and release agent 4 is housed in the body 1.
Above-described only is preferred implementation of the present utility model.Should be understood that; for the person of ordinary skill of the art; under the prerequisite that does not break away from the utility model principle; need not the technical characterictic that the process creative work just can be associated; can also make some modification and improvement; these variations obviously all should be considered as equivalent feature, still belong within the protection domain of the utility model patent.