CN201454557U - Separator tube for blood serum and blood corpuscle - Google Patents

Separator tube for blood serum and blood corpuscle Download PDF

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Publication number
CN201454557U
CN201454557U CN2009200830115U CN200920083011U CN201454557U CN 201454557 U CN201454557 U CN 201454557U CN 2009200830115 U CN2009200830115 U CN 2009200830115U CN 200920083011 U CN200920083011 U CN 200920083011U CN 201454557 U CN201454557 U CN 201454557U
Authority
CN
China
Prior art keywords
blood
serum
tube
haemocyte
tube body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2009200830115U
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Chinese (zh)
Inventor
王军
胡祥
张勇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHENGDU RICH SCIENCE INDUSTRY CO., LTD.
Original Assignee
CHENGDU RUIQI SCIENCE AND TECHNOLOGY INDUSTRIAL Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHENGDU RUIQI SCIENCE AND TECHNOLOGY INDUSTRIAL Co Ltd filed Critical CHENGDU RUIQI SCIENCE AND TECHNOLOGY INDUSTRIAL Co Ltd
Priority to CN2009200830115U priority Critical patent/CN201454557U/en
Application granted granted Critical
Publication of CN201454557U publication Critical patent/CN201454557U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model discloses a separator tube for blood serum and blood corpuscle, which comprises a transparent tube body and a sealing plug matching with the tube body, wherein diameters of cross sections of the tube body decrease gradually from a tube mouth to a tube bottom, an included angle between a tube body wall and a vertical axes is 1.5-1.8 degrees, and the tube body is provided with a separating agent inside. The utility model can completely separate the blood serum and the blood corpuscle in blood without generating turbidity phenomenon while extracting, the viscosity of the separated blood serum is changeless after long time laying, and the blood serum and the blood corpuscle do not mix when slightly oscillating.

Description

Serum and haemocyte separator tube
Technical field
The utility model relates to a kind of medical apparatus, relates in particular to a kind of clinical examination process that is used for, the separator tube that the serum in the blood is separated with haemocyte.
Background technology
At present, separation of serum all adopts the identical cuvette of diameter up and down with haemocyte.Separated plasma to be adopted and adds behind the anti-coagulants way of centrifugation again, blood plasma is separated with haemocyte, but it is muddy easily when getting blood plasma, separate not thorough, blood sample long slightly back standing time is haemolysis easily, if when adopting the automatic analyzer analysed for plasma, the easy blocking pipe of unprecipitated haemocyte, blood plasma must take out and can store.Separation of serum adopts after the blood natural coagulation method of centrifugation more more, when taking out serum and analyze, has a muddy easily problem equally.
In addition, Japanese patent application publication No. Sho 51-83654 discloses a kind of blood testing container, has wherein contained thixotroping serum or plasma separation compositions in the blood collection tube bottom, for example, and the mixture of siloxanes and silica.Blood is collected in the blood collection tube, places reasonable time and centrifugal.Then, gluey serum or plasma separation compositions becomes and can flow under centrifugal action.Simultaneously, the proportion of gluey serum or plasma separation compositions is between serum or plasma component (proportion about 1.02) and blood clot or cellular component (proportion about 1.08) (1.03-1.07).Therefore, isolate compositions floats gradually from the bottom of pipe in collecting blood, and is positioned between serum or plasma layer and blood clot or the cellular layer, to determine successfully separating that serum or plasma fraction separate from blood clot or cellular component.At this moment can from blood collection tube, tell at an easy rate from the serum or the plasma fraction of blood or cellular component separation, carry out various detections.Also can not need transfer to other container storage.But such thixotroping serum or plasma separation compositions can contain the main component except that mentioned component.For example, isolate compositions has advised also containing the reagent of oligomer and adjusting proportion, viscosity and/or thixotropic nature except that containing aforementioned siloxanes.The example of oligomer comprises: halogenated hydrocarbon oligomer, acrylate oligomer, ester oligomer and cyclic hydrocarbon oligomer.The example of conditioning agent comprises inorganic particle such as silica and kaolin and organic gel agent such as benzylidene sorbitol.Yet aforementioned organic siliconresin shows compatibility obviously poor and proportion that be made up of inorganic particle and viscosity modifier, and extremely sensitive to being separated at short notice.Curing reaction takes place when equally, organic siliconresin carries out irradiation-sterilize.Therefore, the organic siliconresin there be limited evidence currently of uses.And the halogenated hydrocarbon oligomer when burning disposal, produces hydrogen halide, and it may cause damage or environment is caused harmful effect incinerator.Each contains a lot of polar groups in molecule for aforementioned acrylate oligomer and ester oligomer, and having when detecting blood concentration increases the problem that drug absorption takes place.
The utility model content
The purpose of this utility model is to overcome the problems referred to above of the separator existence that in the prior art serum in the blood is separated with haemocyte, and a kind of serum and haemocyte separator tube are provided.The utility model can thoroughly separate the serum in the blood with haemocyte, and can not produce turbid phenomenon when extracting, and isolated serum is through the long-time viscosity no change of placing, and serum and haemocyte do not mix through slightly waving yet.
For achieving the above object, the technical solution adopted in the utility model is as follows:
A kind of serum and haemocyte separator tube, comprise transparent tube body and the sealing-plug that cooperates with body, it is characterized in that: the diameter of described body cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis is 1.5 degree, one 1.8 degree, and release agent is housed in the body.
Described sealing-plug is a rubber stopper, and the rubber stopper cross section is " protruding " shape, protruding end and body fitted seal.
Be snapped with splash cap on the described sealing-plug.
Adopt advantage of the present utility model to be:
One, the utility model can thoroughly separate the serum in the blood with haemocyte, and can not produce turbid phenomenon when extracting, the angle that adopts tube body wall and vertical axis is 1.5 degree-1.8 degree, make isolated serum through the long-time viscosity no change of placing, serum and haemocyte do not mix through slightly waving yet.
Two, the utility model has overcome the defective of existing separation of serum or the existence of haemocyte utensil, the efficient and the effect of blood sample analysis are improved greatly, utilize this disposable minute blood test tube, jam-pack rubber stopper behind the branch blood, blood plasma or serum can be stayed in vitro and store, save the storage utensil, simplified the storage means.
Three, the utility model sealing-plug is a rubber stopper, and rubber stopper is " protruding " shape, and protruding end and body fitted seal can be stayed in vitro blood plasma or serum for a long time and stored.
Four, adopt the separator tube of serum of the present utility model and haemocyte, preparation technology is simple, and raw material is easy to get, and cost is low, and environmentally safe.
Description of drawings
Fig. 1 is the utility model structural representation
Fig. 2 adds schematic diagram behind the glue for the utility model
Fig. 3 is the utility model blood sampling back schematic diagram
Fig. 4 is the centrifugal back of a utility model schematic diagram
Be labeled as among the figure: 1, body, 2, sealing-plug, 3, splash cap, 4, release agent, 5, blood, 6, serum, 7, vertical axis, 8, haemocyte.
The specific embodiment
Embodiment 1
A kind of serum and haemocyte separator tube comprise transparent tube body 1 and the sealing-plug 2 that cooperates with body 1, and the diameter of body 1 cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis 7 is 1.5 degree, and release agent 4 is housed in the body 1.Wherein, sealing-plug 2 is a rubber stopper, and the rubber stopper cross section is " protruding " shape, protruding end and body 1 fitted seal.On sealing-plug, be snapped with splash cap 3.
Body material in the utility model is not particularly limited.The example of material comprises, thermoplastic resin, as, polyethylene, polypropylene, polystyrene, PET, polymethyl methacrylate, polyacrylonitrile, polyamide, acrylonitrile.Styrol copolymer and ethene. ethenol copolymer; Thermosetting resin, as, undersaturated polyester, epoxy and epoxy acrylate resin; The natural resin of modification, as, cellulose ethanoate, cellulose propionate, ethyl cellulose, ethyl chitin; Silicate glass, as, soda-soda lime glass, phosphoric acid silicate glass and borosilicate glass; Glass is fused silica for example.The material of listing above both can they be used in combination also and can be used in combination with other secondary materials.Also can use conventional in the prior art known other materials.
The release agent that adopts in the utility model can be made up of the material of following weight:
Macromolecular hydrocarbon 50-85 part; Hydrophobic silica 15-30 part; Its proportion is 1.04-1.05 for 20 ℃, and viscosity is 20 * 10 for 20 ℃ 4-60 * 10 4Cp.
Macromolecular hydrocarbon can be one or more in polybutadiene, polyisobutene, atoleine, the polyglyceryl ether.
Operation principle of the present utility model is as follows:
The blood 5 that injects separator tube can make blood anticoagulant as required or be rapidly solidificated into clot, shrink fast, when centrifugation, at the ask separation layer that form a semisolid of serum 6, when extracting blood plasma or serum with haemocyte 8, because this separation layer is arranged, and the test tube diameter is up big and down small, in the middle of separation layer floats over, the two is isolated well, guaranteed not produce turbid phenomenon, made the separation of blood plasma or serum very thorough.
Embodiment 2
A kind of serum and haemocyte separator tube comprise transparent tube body 1 and the sealing-plug 2 that cooperates with body 1, and the diameter of body 1 cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis 7 is 1.6 degree, and release agent 4 is housed in the body 1.
Embodiment 3
A kind of serum and haemocyte separator tube comprise transparent tube body 1 and the sealing-plug 2 that cooperates with body 1, and the diameter of body 1 cross section is low from the mouth of pipe to pipe to be reduced gradually, and the angle of tube body wall and vertical axis 7 is 1.8 degree, and release agent 4 is housed in the body 1.
Above-described only is preferred implementation of the present utility model.Should be understood that; for the person of ordinary skill of the art; under the prerequisite that does not break away from the utility model principle; need not the technical characterictic that the process creative work just can be associated; can also make some modification and improvement; these variations obviously all should be considered as equivalent feature, still belong within the protection domain of the utility model patent.

Claims (3)

1. serum and haemocyte separator tube, comprise transparent tube body (1) and the sealing-plug (2) that cooperates with body (1), it is characterized in that: the diameter of described body (1) cross section is low from the mouth of pipe to pipe to be reduced gradually, the angle of tube body wall and vertical axis (7) is 1.5 degree-1.8 degree, and release agent (4) is housed in the body (1).
2. serum according to claim 1 and haemocyte separator tube is characterized in that: described sealing-plug (2) is a rubber stopper, and the rubber stopper cross section is " protruding " shape, protruding end and body (1) fitted seal.
3. serum according to claim 1 and haemocyte separator tube is characterized in that: be snapped with splash cap (3) on the described sealing-plug (2).
CN2009200830115U 2009-07-31 2009-07-31 Separator tube for blood serum and blood corpuscle Expired - Fee Related CN201454557U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009200830115U CN201454557U (en) 2009-07-31 2009-07-31 Separator tube for blood serum and blood corpuscle

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009200830115U CN201454557U (en) 2009-07-31 2009-07-31 Separator tube for blood serum and blood corpuscle

Publications (1)

Publication Number Publication Date
CN201454557U true CN201454557U (en) 2010-05-12

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102778382A (en) * 2012-07-29 2012-11-14 宁波市鄞州青林医疗器械技术咨询有限公司 Three-way middle-layer extracting type blood serum separation pipe
CN107209169A (en) * 2015-03-31 2017-09-26 积水医疗株式会社 Serum or blood plasma separation take container with composition and blood
CN113751095A (en) * 2015-12-11 2021-12-07 巴布森诊断公司 Sample container and method for separating serum or plasma from whole blood

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102778382A (en) * 2012-07-29 2012-11-14 宁波市鄞州青林医疗器械技术咨询有限公司 Three-way middle-layer extracting type blood serum separation pipe
CN107209169A (en) * 2015-03-31 2017-09-26 积水医疗株式会社 Serum or blood plasma separation take container with composition and blood
US10617602B2 (en) 2015-03-31 2020-04-14 Sekisui Medical Co., Ltd. Composition for serum or plasma separation, and container for blood collection
CN113751095A (en) * 2015-12-11 2021-12-07 巴布森诊断公司 Sample container and method for separating serum or plasma from whole blood
US11697114B2 (en) 2015-12-11 2023-07-11 Babson Diagnostics, Inc. Centrifugation method separating serum or plasma from whole blood using a specimen container having a cap to retain blood cells
CN113751095B (en) * 2015-12-11 2024-01-09 巴布森诊断公司 Sample container and method for separating serum or plasma from whole blood

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Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: CHENGDU RICH SCIENCE INDUSTRY CO., LTD.

Free format text: FORMER NAME: CHENGDU RUIQI SCIENCE AND TECHNOLOGY INDUSTRIAL CO., LTD.

CP03 Change of name, title or address

Address after: 611731, 66, Tian Qin East Street, Chengdu hi tech Zone (West District, Sichuan)

Patentee after: CHENGDU RICH SCIENCE INDUSTRY CO., LTD.

Address before: 611731, No. 21, West core road, hi tech West District, Sichuan, Chengdu

Patentee before: Chengdu Ruiqi Science and Technology Industrial Co., Ltd.

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100512

Termination date: 20170731

CF01 Termination of patent right due to non-payment of annual fee