CN103499525A - Blood sample biochemical quantitative detection device - Google Patents
Blood sample biochemical quantitative detection device Download PDFInfo
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- CN103499525A CN103499525A CN201310392693.9A CN201310392693A CN103499525A CN 103499525 A CN103499525 A CN 103499525A CN 201310392693 A CN201310392693 A CN 201310392693A CN 103499525 A CN103499525 A CN 103499525A
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Abstract
The invention discloses a blood sample biochemical quantitative detection device used for blood samples. The device comprises a capillary centrifugal unit, a spectrum detection unit, and a signal processing unit. The blood sample biochemical quantitative detection device also comprises supporting devices of a capillary blood collection device, a capillary cap, a hollow needle, and a vacuum test tube reactor. A blood sample is collected through the capillary blood collection device; cells and plasma are separated through centrifugation; the capillary is broken by hand, and the plasma part is fetched; the needle is sleeved on, and is injected into the vacuum test tube reactor, such that a quantitative reaction of the plasma and a biochemical reagent is carried out; the reaction result is detected through spectrum; through the analysis of the signal processing unit, the result is displayed on a liquid crystal screen. The device provided by the invention has the advantaged of simple operation, and low sample consumption. With the device, requirements of clinical sample detection or routine biochemical sample quantitative detection can be well satisfied.
Description
Technical field
The invention belongs to a kind of biochemical detection device, specifically the biochemical quantitative testing device of a kind of blood sample.
Background technology
In the medical diagnosis process, the doctor often need carry out to patient's blood sample biochemistry and quantitatively detect, such as blood sugar, blood fat etc., and the diagnosis that its testing result can be the doctor provides reliable foundation.When blood sample is carried out to biochemistry detection, often need first remove the cell in blood, then the various materials in blood plasma be carried out to quantitative test.For example, lipid examination is mainly a kind of method for quantitatively determining that contained lipid in blood plasma is carried out.Blood fat extensively is present in human body, is the basic metabolism material of human body cell.The Main Ingredients and Appearance of blood fat is triglyceride and cholesterol, wherein, the metabolism of triglyceride participant energy i (in vivo), cholesterol is mainly used in synthetic cell serous coat, steroid hormone and bile acid.To the quantitative testing result of blood fat can antimer in the situation of lipid metabolism.Because the rising of plasma cholesterol and triglyceride level is relevant with atherosclerotic generation, these two main projects that become lipid determination.Therefore, a kind of Quantitative detection device that can be used for blood sample of development and Design has very important significance.
Summary of the invention
The purpose of this invention is to provide the biochemical quantitative testing device of a kind of blood sample, the advantage such as that this device has is simple to operate, the sample consumption is few.
The object of the present invention is achieved like this:
The biochemical quantitative testing device of a kind of blood sample, comprise kapillary centrifugal unit, spectral detection unit, signal processing unit, the biochemical quantitative testing device of described blood sample also comprises matching used kapillary hemostix, kapillary headgear, hollow pinhead and vacuum test tube reactor.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, wherein said kapillary centrifugal unit is provided with the sample storage unit with kapillary hemostix coupling.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, wherein said spectral detection unit can adopt different-waveband to carry out spectral detection according to the biochemistry detection demand.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, wherein said signal processing unit can be collected the different-waveband spectral signal according to the biochemistry detection demand and be processed.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, wherein said kapillary hemostix inwall scribbles anti-coagulants, and kapillary one scale place processes through emery wheel in advance, can at this scale place, by record book in accordion form, be broken easily.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, wherein said hollow pinhead tail end can insert a capillary hemostix.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, wherein said kapillary headgear is made by organic polymer material, can be enclosed within kapillary hemostix one end.
Preferably, the biochemical quantitative testing device of above-mentioned blood sample, the container that wherein said vacuum test tube reactor is transparent material, soda acid that can anti-some strength, the required reagent of biochemistry detection is housed in the test-tube reaction device in advance, Vacuum Package, its sealing part rubber diaphragm can be by punctures.
Compared with prior art, the biochemical quantitative testing device of the blood sample the present invention relates to has following advantage and marked improvement: the present invention utilizes kapillary to complete collection and the pre-service of blood sample; Utilize the negative pressure of vacuum test tube, when punctures caulking gum film, plasma sample is introduced to reaction tank, with the biochemical reagents that prestore in vacuum test tube, carry out quantitative reaction; After having reacted, vacuum test tube can be put into to the spectral detection unit reaction result is carried out to quantitative test; According to the object difference detected, can be at the vacuum test tube different biochemical reagents that prestore, the spectral detection unit can adopt different-waveband to carry out quantitative test to reaction result.
The accompanying drawing explanation
Fig. 1: apparatus of the present invention structural representation; Wherein 1 is the kapillary centrifugal unit, and 2 is the spectral detection unit, and 3 is signal processing unit.
Fig. 2: (A) vacuum test tube reactor, wherein 4 is the sealing rubber diaphragm, 5 is prepackage biochemical reagents in vitro; (B) kapillary hemostix, wherein 6 is blood sampling total amount indicating graduation, 7 for fractureing indicating graduation; (C) vacuum syringe needle; (D) kapillary headgear.
Fig. 3: the design sketch of (A) after the kapillary sampling, loading onto headgear; (B) kapillary puts the design sketch of syringe needle after fractureing.
Embodiment
Below in conjunction with accompanying drawing and application examples, the present invention is done further and describes in detail.
The biochemical quantitative testing device of blood sample of the present invention, as shown in Figure 1, comprising: 1 kapillary centrifugal unit, 2 spectral detection unit, 3 signal processing units.Accompanying drawing 2(A) be depicted as the vacuum test tube reactor, wherein 4 is the sealing rubber diaphragm, and 5 is prepackage biochemical reagents in vitro; The vacuum test tube reactor is the test tube shape container of a transparent material, soda acid that can anti-some strength, the required reagent of biochemistry detection is housed in container in advance, Vacuum Package, its sealing part rubber diaphragm can be by punctures, thereby can will be enclosed within plasma sample in the kapillary of syringe needle tail end by negative pressure and introduce test tube, and react with the biochemical reagents of in vitro prepackage.Accompanying drawing 2(B) be depicted as the kapillary hemostix, wherein 6 is blood sampling total amount indicating graduation, and 7 is the kapillary indicating graduation that fractures, and this scale place through the emery wheel processing, makes it be easy to fracture in advance; Accompanying drawing 2(C) be depicted as the vacuum syringe needle, the tail end of syringe needle can put a capillary and use; Accompanying drawing 2(D) be depicted as the kapillary headgear, made by organic polymer material, can be enclosed within kapillary one end, prevent that sample runs off when centrifugal.Accompanying drawing 3(A) be depicted as after kapillary is sampled the design sketch of loading onto headgear; Accompanying drawing 3(B) be depicted as after kapillary fractures the design sketch that puts syringe needle.
Example 1: the content that detects patient's Blood Cholesterol.
Cholesterol in human body is mainly used in synthetic cell serous coat, steroid hormone and bile acid.Because the rising of plasma cholesterol is relevant with atherosclerotic generation, the content of Blood Cholesterol has become an important indication of health.
Cholesterol level detects:
(1) reactor is prepared: will join in the vacuum test tube reactor with cholesterol specificity biochemical reaction reagent, and then reactor will be pumped into to-0.5 atmospheric pressure, and be sealed with rubber diaphragm;
(2) blood sampling: use the kapillary hemostix to gather patient's blood, stop gathering when blood arrives scale 6, the anti-coagulants and the reaction of blood that now in capillary wall, apply, guarantee that blood does not solidify;
(3) centrifugal: as the kapillary headgear to be enclosed within to the capillary sample inlet end, and to be placed in kapillary centrifugal unit 1 and to carry out centrifugally operated;
(4) after centrifugal, in the kapillary hemostix, blood plasma separates with haemocyte, now from kapillary scale 7 kapillary that fractures, retains scale has blood plasma part more than 7;
(5) sample introduction reaction: put syringe needle to the capillary portion retained, insert preprepared vacuum test tube reactor, in punctures sealing rubber diaphragm 4, negative pressure is introduced test tube by blood plasma in kapillary, and is reacted with the cholesterol specificity biochemical reaction reagent 5 prestored;
(5) detect: after completion of the reaction, test tube is inserted in the sample cell of spectral detection unit 2 and carries out optical detection, the result of detection, by after signal processing unit 3 acquisition process, is presented at result on liquid crystal display.
Those skilled in the art will readily understand; the foregoing is only preferred embodiment of the present invention; not in order to limit the present invention, all any modifications of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.
Claims (8)
1. the biochemical quantitative testing device of a blood sample, comprise kapillary centrifugal unit, spectral detection unit, signal processing unit, it is characterized in that: the biochemical quantitative testing device of described blood sample also comprises matching used kapillary hemostix, kapillary headgear, hollow pinhead and vacuum test tube reactor.
2. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: described kapillary centrifugal unit is provided with the sample storage unit with kapillary hemostix coupling.
3. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: described spectral detection unit can adopt different-waveband carry out spectral detection according to the biochemistry detection demand.
4. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: described signal processing unit can be collected the different-waveband spectral signal according to the biochemistry detection demand and be processed.
5. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: described kapillary hemostix inwall scribbles anti-coagulants, and kapillary one scale place processes through emery wheel in advance, can at this scale place, by record book in accordion form, be broken easily.
6. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: described hollow pinhead tail end can insert a capillary hemostix.
7. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: described kapillary headgear is made by organic polymer material, can be enclosed within kapillary hemostix one end.
8. the biochemical quantitative testing device of blood sample according to claim 1, it is characterized in that: the container that described vacuum test tube reactor is transparent material, soda acid that can anti-some strength, the required reagent of biochemistry detection is housed in the test-tube reaction device in advance, Vacuum Package, its sealing part rubber diaphragm can be by punctures.
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| CN201310392693.9A CN103499525A (en) | 2013-09-03 | 2013-09-03 | Blood sample biochemical quantitative detection device |
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| CN201310392693.9A CN103499525A (en) | 2013-09-03 | 2013-09-03 | Blood sample biochemical quantitative detection device |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104762200A (en) * | 2015-04-08 | 2015-07-08 | 冯晓均 | Nucleic acid detection reaction tube and application method thereof |
| CN107764881A (en) * | 2017-11-27 | 2018-03-06 | 民康医疗科技（天津）有限公司 | A kind of portable blood test kit device based on electrochemical method |
| CN107874767A (en) * | 2017-10-12 | 2018-04-06 | 杭州博拓生物科技股份有限公司 | The device of analyte in a kind of detection sample |
| CN108872560A (en) * | 2018-08-14 | 2018-11-23 | 湖北伽诺美生物科技有限公司 | A kind of portable urine quantitative testing device |
| CN110201548A (en) * | 2019-04-23 | 2019-09-06 | 江苏科华医疗器械科技有限公司 | A kind of quick peripheral plasma collector and its application method |
| CN110879292A (en) * | 2019-11-29 | 2020-03-13 | 重庆大学 | Blood physical and chemical analysis method |
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| JP2005291726A (en) * | 2004-03-31 | 2005-10-20 | Fujifilm Techno Products Co Ltd | Biochemical analyzer |
| CN201073303Y (en) * | 2007-02-11 | 2008-06-18 | 陈士连 | Disposable trace quantity blood samplingd evice |
| CN101943697A (en) * | 2010-09-01 | 2011-01-12 | 杨军 | Blood examination method, system and microchip |
| CN102316989A (en) * | 2009-02-17 | 2012-01-11 | 霍夫曼-拉罗奇有限公司 | Be used to provide the method and apparatus of blood constitutent |
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| CN2128870Y (en) * | 1992-03-03 | 1993-03-31 | 黄永强 | Disposable blood sampler |
| JP2005291726A (en) * | 2004-03-31 | 2005-10-20 | Fujifilm Techno Products Co Ltd | Biochemical analyzer |
| CN201073303Y (en) * | 2007-02-11 | 2008-06-18 | 陈士连 | Disposable trace quantity blood samplingd evice |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104762200A (en) * | 2015-04-08 | 2015-07-08 | 冯晓均 | Nucleic acid detection reaction tube and application method thereof |
| CN104762200B (en) * | 2015-04-08 | 2016-06-08 | 冯晓均 | A kind of nuclease assay reaction pipe and using method thereof |
| CN107874767A (en) * | 2017-10-12 | 2018-04-06 | 杭州博拓生物科技股份有限公司 | The device of analyte in a kind of detection sample |
| CN107874767B (en) * | 2017-10-12 | 2020-11-24 | 杭州博拓生物科技股份有限公司 | Device for detecting analyzed substance in sample |
| CN107764881A (en) * | 2017-11-27 | 2018-03-06 | 民康医疗科技（天津）有限公司 | A kind of portable blood test kit device based on electrochemical method |
| CN108872560A (en) * | 2018-08-14 | 2018-11-23 | 湖北伽诺美生物科技有限公司 | A kind of portable urine quantitative testing device |
| CN110201548A (en) * | 2019-04-23 | 2019-09-06 | 江苏科华医疗器械科技有限公司 | A kind of quick peripheral plasma collector and its application method |
| CN110879292A (en) * | 2019-11-29 | 2020-03-13 | 重庆大学 | Blood physical and chemical analysis method |
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Application publication date: 20140108 |