CN107753580A - A kind of concocting method of moutan bark - Google Patents

A kind of concocting method of moutan bark Download PDF

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Publication number
CN107753580A
CN107753580A CN201711017322.7A CN201711017322A CN107753580A CN 107753580 A CN107753580 A CN 107753580A CN 201711017322 A CN201711017322 A CN 201711017322A CN 107753580 A CN107753580 A CN 107753580A
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Prior art keywords
moutan bark
electric field
rice wine
yellow rice
boiling
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CN201711017322.7A
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Chinese (zh)
Inventor
李素亮
李保明
魏庆红
刘爱珍
罗云
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ANHUI XIEHECHENG PHARMACEUTICAL PIECES Co Ltd
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ANHUI XIEHECHENG PHARMACEUTICAL PIECES Co Ltd
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Priority to CN201711017322.7A priority Critical patent/CN107753580A/en
Publication of CN107753580A publication Critical patent/CN107753580A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of concocting method of moutan bark, the moutan bark after cleaning is infiltrated using common salt aqueous solution in the present invention, moutan bark after softening without hinder water, tacky phenomenon occurs, it is soft or hard suitable, suitable section, boiling is impregnated using the mixing juice of cultivated land, mulberries and the Radix Astragali afterwards, during drying simultaneously, moutan bark is infiltrated using boiling remaining mixing juice, the toxicity of moutan bark is effectively reduced, improves the active constituent content and species of moutan bark;Again after the vexed profit of yellow rice wine, the drug effect for improving moutan bark is improved;Under high voltage electric field, interim drying process is used to moutan bark, effectively improve rate of drying, shorten the whole Preparation process cycle of moutan bark, and by controlling temperature, low temperature drying is realized, the active ingredients such as paeonol is significantly retained, reach bactericidal action simultaneously, Product quality and safety is stable.

Description

A kind of concocting method of moutan bark
Technical field
The invention belongs to Chinese medicine processing technique field, and in particular to a kind of concocting method of moutan bark.
Background technology
Moutan bark also known as the root bark of tree peony, it is a kind of parts of generic medicinal plants, is cohosh tree peony Paeonia suffruticosa Andr. root skin, cold nature, bitter, pungent, the thoughts of returning home, liver and kidney channel, there is the effect of clearing heat and cooling blood, promoting blood circulation and removing blood stasis;《Middle traditional Chinese medicines Allusion quotation》In versions one in 2010:Point out that its processing method is under " moutan bark " item:Autumn excavates root, removes radicula and silt, Root skin is stripped, dries or scrape off tertia, core is removed, dries, the former practises the title even root bark of tree peony, and the latter practises title and scrapes the root bark of tree peony, at present, market The processed goods of upper moutan bark scrapes the root bark of tree peony, the even root bark of tree peony and red palpus, and three of the above processed goods does not do cutting processing, sold to medicine materical crude slice Processing enterprise carries out wetting softening section again.
Show according to the study, moutan bark contains paeonol and its glucoside, and its paeonol is principle active component, there is antipyretic, calm, town Bitterly, anti-inflammatory, antiallergy etc. act on;Paeonol not high heat resistance, 49.5-50.5 DEG C of fusing point, can be dissolved in water, can with steam distillation, Even if also can slowly distilling at normal temperatures.
There is Primary Study to show, moutan bark, which carries out taking advantage of fresh-cut system, can reduce following process program, preferably retain in medicinal material Active ingredient.Therefore need to research and develop a kind of processing method to fresh moutan bark medicine materical crude slice, while can farthest avoid Paeonol piece drug effect is lost.
The content of the invention
The property of medicine of moutan bark in order to better improve, it is an object of the invention to provide a kind of concocting method of moutan bark.
The present invention is achieved by the following technical solutions:
A kind of concocting method of moutan bark, by moutan bark medicinal material is cleaned, saline solution immersion, after slicing treatment, adds cultivated land, mulberries After Radix Astragali mixing Chinese medicine juice boiling, dry, add the vexed profit of yellow rice wine, then be placed in high voltage electric field next stage property dry after, packaging Get product;
During the stage of the high voltage electric field is dried, moutan bark surface is carried out using remaining mixing Chinese medicine juice after boiling Infiltration is handled.
Concrete technology step is as follows:
(1)Cleaning, section:
After moutan bark fresh medicine material is cleaned, drained, soaked 20-30 minutes using 2-5% common salt aqueous solutions, fully after infiltration Taking-up drains, and In Shade drying 20-40 hours, extracts wooden core, shave out;
(2)Boiling:
Moutan bark after above-mentioned section is added to cultivated land, mulberries with Radix Astragali mixing Chinese medicine juice, water-bath is placed in after mixing thoroughly It is interior, it is warming up to and boils, mixing cooks 20-40 minutes, then takes out moutan bark, cools, and shady place is dried to four to sixty percent dry, It is stand-by;
(3)The vexed profit of yellow rice wine:
By step(2)Moutan bark is put into pot, is then added quantitative yellow rice wine and is mixed vexed profit thoroughly, stews to moisten to yellow rice wine and blotted, then steam 4-6 hours, take out;
(4)High electric field drying processing:
Will above-mentioned moutan bark take out after dry in the air to three to fifty percent dry, place into high electric field drying machine, 2-3 handled at 43-48 DEG C After hour, take out;
By step(2)After remaining mixing Chinese medicine juice is diluted with 2-4 times of yellow rice wine after boiling, centrifuging and taking supernatant, by supernatant It is sprayed on moutan bark surface, its surface is kept moisture state, after placing 10-20 minutes, places into high electric field drying machine It is interior, handle 1-2 hours in 50-55 DEG C;
(5)Packaging:
Moutan bark after drying is aseptically dispensed, you can finished product.
Wherein, the step(1)It is 1-3mm that slicing treatment, which controls the thickness of tree peony skin graft,.
Wherein, the step(2)Middle cultivated land, mulberries refer to three according to 2 with Radix Astragali mixing Chinese medicine juice:3:0.5-1's Mass ratio mixes, and adds appropriate distilled water, squeezes the juice and produce through juice extractor, and the mixed liquor dosage is 2-4 times of moutan bark quality.
Wherein, the step(3)Middle yellow rice wine dosage is moutan bark quality 1/5-1/2.
Wherein, the step(4)Middle setting high electric field drying machine electric field strength is in 300-400kV/m.
The present invention has the beneficial effect that:
(1)The moutan bark after cleaning is infiltrated using common salt aqueous solution in the present invention, the moutan bark surface color after softening It is deep slightly compared with crude drug, without hinder water, tacky phenomenon occurs, soft or hard suitable, suitable section, afterwards using cultivated land, mulberries and the Radix Astragali The dipping boiling of mixing juice, while during high electric field drying, moutan bark is carried out using boiling remaining mixing juice Infiltration, makes full use of resource, effectively reduces the toxicity of moutan bark, improves the active constituent content and species of moutan bark;Pass through again After the vexed profit of yellow rice wine, improve and improve the clearing heat and cooling blood of moutan bark, activate blood circulation and disperse blood clots, the drug effect such as reducing the asthenic fever.
(2)Under high voltage electric field, using interim drying process, rate of drying is effectively improved, effectively shortens drying time, The whole Preparation process cycle of moutan bark is shortened, and by controlling temperature, realizes low temperature drying, moutan bark material during drying Hardly heat up, the active ingredients such as paeonol is significantly retained, dry after piece type it is intact, while make enzyme inactivate or Passivation, reaches bactericidal action, prevents from causing microorganism pollution, and Product quality and safety is stable, avoids caused by long-term storage Loss of effective components.
Embodiment
A kind of concocting method of moutan bark, by moutan bark medicinal material is cleaned, saline solution immersion, after slicing treatment, add cultivated land, Mulberries with after Radix Astragali mixing Chinese medicine juice boiling, dry, add the vexed profit of yellow rice wine, then be placed in high voltage electric field next stage property dry after, Packaging is got product;
During the stage of the high voltage electric field is dried, moutan bark surface is carried out using remaining mixing Chinese medicine juice after boiling Infiltration is handled.
Concrete technology step is as follows:
(1)Cleaning, section:
After moutan bark fresh medicine material is cleaned, drained, soaked 25 minutes using 5% common salt aqueous solution, fully take out drip after infiltration It is dry, it is In Shade to dry 30 hours, extract wooden core, shave out;
(2)Boiling:
Moutan bark after above-mentioned section is added to cultivated land, mulberries with Radix Astragali mixing Chinese medicine juice, water-bath is placed in after mixing thoroughly It is interior, it is warming up to and boils, mixing cooks 20 minutes, then takes out moutan bark, cools, shady place is dried to four one-tenth and done, stand-by;
(3)The vexed profit of yellow rice wine:
By step(2)Moutan bark is put into pot, is then added quantitative yellow rice wine and is mixed vexed profit thoroughly, stews to moisten to yellow rice wine and blotted, then steam 5 Hour, take out;
(4)High electric field drying processing:
Will above-mentioned moutan bark take out after dry in the air to three to fifty percent dry, place into high electric field drying machine, handled 2 hours at 45 DEG C Afterwards, take out;
By step(2)After remaining mixing Chinese medicine juice is diluted with 3 times of yellow rice wine after boiling, centrifuging and taking supernatant, supernatant is sprayed It is sprinkled upon on moutan bark surface, its surface is kept moisture state, after placing 20 minutes, places into high electric field drying machine, in 52 DEG C are handled 2 hours;
(5)Packaging:
Moutan bark after drying is aseptically dispensed, you can finished product.
Wherein, the step(1)It is 1-3mm that slicing treatment, which controls the thickness of tree peony skin graft,.
Wherein, the step(2)Middle cultivated land, mulberries refer to three according to 2 with Radix Astragali mixing Chinese medicine juice:3:1 quality Than mixing, appropriate distilled water is added, squeezes the juice and produces through juice extractor, the mixed liquor dosage is 4 times of moutan bark quality.
Wherein, the step(3)Middle yellow rice wine dosage is moutan bark quality 1/2.
Wherein, the step(4)Middle setting high electric field drying machine electric field strength is in 360kV/m.

Claims (6)

1. a kind of concocting method of moutan bark, it is characterised in that by moutan bark medicinal material is cleaned, saline solution soaks, slicing treatment Afterwards, add cultivated land, mulberries and after Radix Astragali mixing Chinese medicine juice boiling, dry, add the vexed profit of yellow rice wine, then be placed in the high voltage electric field next stage Property dry after, packaging is got product;
During the stage of the high voltage electric field is dried, moutan bark surface is carried out using remaining mixing Chinese medicine juice after boiling Infiltration is handled.
2. the concocting method of a kind of moutan bark according to claim 1, it is characterised in that concrete technology step is as follows:
(1)Cleaning, section:
After moutan bark fresh medicine material is cleaned, drained, soaked 20-30 minutes using 2-5% common salt aqueous solutions, fully after infiltration Taking-up drains, and In Shade drying 20-40 hours, extracts wooden core, shave out;
(2)Boiling:
Moutan bark after above-mentioned section is added to cultivated land, mulberries with Radix Astragali mixing Chinese medicine juice, water-bath is placed in after mixing thoroughly It is interior, it is warming up to and boils, mixing cooks 20-40 minutes, then takes out moutan bark, cools, and shady place is dried to four to sixty percent dry, It is stand-by;
(3)The vexed profit of yellow rice wine:
By step(2)Moutan bark is put into pot, is then added quantitative yellow rice wine and is mixed vexed profit thoroughly, stews to moisten to yellow rice wine and blotted, then steam 4-6 hours, take out;
(4)High electric field drying processing:
Will above-mentioned moutan bark take out after dry in the air to three to fifty percent dry, place into high electric field drying machine, 2-3 handled at 43-48 DEG C After hour, take out;
By step(2)After remaining mixing Chinese medicine juice is diluted with 2-4 times of yellow rice wine after boiling, centrifuging and taking supernatant, by supernatant It is sprayed on moutan bark surface, its surface is kept moisture state, after placing 10-20 minutes, places into high electric field drying machine It is interior, handle 1-2 hours in 50-55 DEG C;
(5)Packaging:
Moutan bark after drying is aseptically dispensed, you can finished product.
A kind of 3. concocting method of moutan bark according to claim 2, it is characterised in that the step(1)Slicing treatment The thickness for controlling tree peony skin graft is 1-3mm.
A kind of 4. concocting method of moutan bark according to claim 2, it is characterised in that the step(2)Middle cultivated land, mulberry Shen refers to three according to 2 with Radix Astragali mixing Chinese medicine juice:3:0.5-1 mass ratio mixing, adds appropriate distilled water, through juice extractor Squeeze the juice and produce, the mixed liquor dosage is 2-4 times of moutan bark quality.
A kind of 5. concocting method of moutan bark according to claim 2, it is characterised in that the step(3)Middle yellow rice wine is used Measure as moutan bark quality 1/5-1/2.
A kind of 6. concocting method of moutan bark according to claim 2, it is characterised in that the step(4)It is middle that height is set Piezoelectric field drying machine electric field strength is in 300-400kV/m.
CN201711017322.7A 2017-10-26 2017-10-26 A kind of concocting method of moutan bark Pending CN107753580A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108743679A (en) * 2018-08-22 2018-11-06 太和县乐民现代农业科技有限公司 A kind of preparation method of Instant moutan bark medicine materical crude slice
CN109091544A (en) * 2018-09-28 2018-12-28 安徽汇中州中药饮片有限公司 Cortex moutan process of preparing technique
CN110664859A (en) * 2019-10-18 2020-01-10 安徽戊庚中药饮片有限责任公司 Processing method based on traditional Chinese medicine decoction pieces and preparation method thereof
CN115381897A (en) * 2021-05-25 2022-11-25 四川新荷花中药饮片股份有限公司 Preparation method of fritillaria cirrhosa powder

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204388482U (en) * 2014-12-26 2015-06-10 东莞市立马干燥技术有限公司 high voltage electric field vacuum drying system

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Publication number Priority date Publication date Assignee Title
CN204388482U (en) * 2014-12-26 2015-06-10 东莞市立马干燥技术有限公司 high voltage electric field vacuum drying system

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108743679A (en) * 2018-08-22 2018-11-06 太和县乐民现代农业科技有限公司 A kind of preparation method of Instant moutan bark medicine materical crude slice
CN109091544A (en) * 2018-09-28 2018-12-28 安徽汇中州中药饮片有限公司 Cortex moutan process of preparing technique
CN110664859A (en) * 2019-10-18 2020-01-10 安徽戊庚中药饮片有限责任公司 Processing method based on traditional Chinese medicine decoction pieces and preparation method thereof
CN115381897A (en) * 2021-05-25 2022-11-25 四川新荷花中药饮片股份有限公司 Preparation method of fritillaria cirrhosa powder

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