CN109289007A - The fresh cutting processing method of Yujin slices - Google Patents
The fresh cutting processing method of Yujin slices Download PDFInfo
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- CN109289007A CN109289007A CN201811172137.XA CN201811172137A CN109289007A CN 109289007 A CN109289007 A CN 109289007A CN 201811172137 A CN201811172137 A CN 201811172137A CN 109289007 A CN109289007 A CN 109289007A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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Abstract
The present invention provides a kind of fresh cutting processing method of Yujin slices, and detailed process is then stepping after the cleaning of fresh Radix Curcumae medicinal material, slice can be obtained purpose medicine materical crude slice using the dry combination method drying of hot-air seasoning-intermittent type microwave.The advantages of the present invention are: Radix Curcumae medicinal material fresh-cut technical operation of the invention is convenient, combined by hot-air seasoning with microwave drying, control hot-air seasoning degree, which enters microwave drying process, can guarantee that the effective component in Radix Curcumae medicinal material retains to greatest extent, Yujin slices piece shape integrality is kept simultaneously, to guarantee Yujin slices quality, it can avoid as acquisition Yujin slices and the wasting of resources caused by Radix Curcumae medicinal material secondary operation and effective component loss, shorten the production cycle, reduce production cost, ensure prepared slice quality, with good industrialization prospect, social effect and economic value.
Description
Technical field
The present invention relates to Chinese medicine processing methods, more particularly, to medicine materical crude slice fresh cutting processing method.
Background technique
Radix Curcumae is zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y.H.Chen et C.Ling, turmeric Curcuma
Longa L., Guangxi zedoary Curcuma kwangsiensis S.G.Lee et C.F.Liang or zedoary Curcuma
The dried root of phaeocaulis Val., has activating microcirculation and removing stasis medicinal, and promoting qi circulation and removing obstruction in the collateral and other effects is tcm clinical practice treatment chest and abdomen thorn
Bitterly, chest impediment and cardialgia, one of conventional Chinese medicines of cards such as amenorrhea and algomenorrhea, swollen breasts.Modern research shows that master contained by Chinese medicine Radix Curcumae
It wants active constituent based on the sesquiterpenoids such as curdione, germacrone, furanodiene, β elemene, has heat unstable
Fixed feature, antitumor, antithrombotic, in terms of show stronger pharmacological activity, such as beta-elemene, germacrone, cowherb
Art diketone, furanodiene etc. all have the stronger antitumor action for inhibiting growth of tumour cell and inducing apoptosis of tumour cell；
Beta-elemene, curdione etc. have the effects that antithrombotic, improve blood circulation；Rcumenol, germacrone, curdione etc. have
Significant anti-inflammatory and analgesic effect.In view of the significant pharmacological activity of Radix Curcumae, development and application is more and more widely paid close attention to.
The processing method of Yujin slices is carried out using Habitat producing and process of preparing as two independent links at present.According to
" Chinese Pharmacopoeia " (version in 2015, one) regulation: the processing method of Radix Curcumae medicinal material is to excavate after winter cauline leaf is withered, removes silt
And radicula, it steams or boils to the saturating heart, it is dry；The concocting method of Yujin slices are as follows: medicinal material cleaned, moisturized, shave, drying.It is strongly fragrant
The existing processing technology parameter of golden medicinal material is to steam or boil 20-40 minutes, is dried 5-15 days, need to be depending on weather conditions, if encountering
Rainy weather, easily moldy metamorphism.After Radix Curcumae medicinal material enters Manufacture of medicinal slices of TCM enterprise, Yujin slices are reprocessed into, it is existing to add
Work technical parameter are as follows: medicinal material was dried 4-6 hours with cold water soak 10-12 hours, demulcen 8-10 hours, and the production cycle is long, and at
Product medicine materical crude slice percentage of damage is high；Also have and Yujin slices, although shortening process time, medicine are processed using chip drying technology after steaming profit
The effective component that material undergoes heating to will cause the thermally labiles such as curdione, germacrone, furanodiene, beta-elemene again is secondary
Loss, causes prepared slice quality to reduce.It can be seen that Radix Curcumae fresh medicinal material, which is processed into medicine materical crude slice, experienced secondary water process and heat treatment, no
The only resources such as waste of manpower, material resources will also result in effective component and be largely lost, and prepared slice quality is irregular, and then causes curative effect
It is unstable.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of production cycle that can be shortened medicine materical crude slice, labor intensity is reduced, is subtracted
It is lost to few effective component, produces the fresh cutting processing method of high-quality Yujin slices.
The technical solution of the present invention is to provide a kind of fresh cutting processing methods of Yujin slices, after the cleaning of fresh Radix Curcumae medicinal material
Stepping, slice, then using the dry medicine materical crude slice of the dry combination method of hot-air seasoning-intermittent type microwave.
Wherein hot-air seasoning to moisture content is 20%-30%, microwave drying to moisture content 10%-12%.
Further, hot-air seasoning temperature is 45-75 DEG C, and the time is 3-9 hours；Microwave drying power is 1-5kW, is often done
Dry 1-5 minutes interval 1-3 minutes.
Further, it is 1.8-4.2mm that slice thickness is controlled when slice.
Further, stepping is to be divided into 2-3 grades according to medicinal material transverse diameter size.
Further, include the steps that cooling, nature after the dry medicine materical crude slice of the dry combination method of hot-air seasoning-intermittent type microwave
It is cooled to room temperature.
Further, cleaning medicinal material is the soil adhered to using tumbling-box type medicine-washing machine clean the surface；Stepping is to pass through screening
Machine is sieved according to medicinal material transverse diameter.
The advantages of the present invention: Radix Curcumae medicinal material fresh-cut technical operation of the invention is convenient, can avoid to obtain
Yujin slices and the wasting of resources caused by Radix Curcumae medicinal material secondary operation and effective component loss, shorten the production cycle, reduce life
Produce cost, it is ensured that prepared slice quality has good industrialization prospect, social effect and economic value.
Detailed description of the invention
Fig. 1 is that five active constituent curdiones, rcumenol, germacrone, furanodiene, beta-elemene mixing reference substance are molten
Liquid high-efficient liquid phase chromatogram, wherein
Curdione (t=17.284min), rcumenol (t=21.713min), germacrone (t=28.972min), furans
Diene (t=37.186min), beta-elemene (t=45.118min).
Fig. 2 is the high-efficient liquid phase chromatogram of 1 gained medicine materical crude slice of embodiment.
Fig. 3 is the high-efficient liquid phase chromatogram of 2 gained medicine materical crude slice of embodiment.
Fig. 4 is the high-efficient liquid phase chromatogram of 3 gained medicine materical crude slice of embodiment.
Fig. 5 is the high-efficient liquid phase chromatogram of medicine materical crude slice obtained by comparative example.
Specific embodiment
The invention will be further described With reference to embodiment.
Yujin slices fresh cutting processing method of the invention, by the way that by stepping after the cleaning of fresh Radix Curcumae medicinal material, then slice is adopted
It can be obtained target product with the dry medicine materical crude slice of the dry combination method of hot-air seasoning-intermittent type microwave, wherein in order to improve cleaning efficiency
Guarantee cleaning quality, it is preferred to use tumbling-box type medicine-washing machine cleaning medicinal material surface soil, it should be pointed out that other cleaning way examples
As cleaned the also achievable present invention by hand；Medicinal material after cleaning, which is carried out screening stepping, can facilitate subsequent slice, furthermore medicinal material
Stepping and slice thickness cooperate, and are conducive to improve drying efficiency, and make it is uniform with the dry quality of medicinal material of a batch, improve at
Product rate；Drying process is combined using hot-air seasoning with microwave drying, and control hot-air seasoning degree enters microwave drying process can
Guarantee that the effective component in Radix Curcumae medicinal material retains to greatest extent, while keeping Yujin slices piece shape integrality, to guarantee Radix Curcumae
Prepared slice quality.
Embodiment 1
The present invention provides a kind of fresh cutting processing method of Yujin slices, includes the following steps:
(1) it cleans: after fresh Radix Curcumae medicinal material harvesting, using the soil of tumbling-box type medicine-washing machine clean the surface attachment；
(2) fresh Radix Curcumae medicinal material stepping: is divided into 2 grades by transverse diameter size by screening machine；
(3) it is sliced: using microtome, slice thickness 2.0mm；
(4) dry: using the dry medicine materical crude slice of the dry combination method of hot-air seasoning-intermittent type microwave, hot air circulation drying temperature is
50 DEG C, the time is 6.5 hours；Microwave drying power is 2kW, the interval 2 minutes of every drying 3 minutes, until moisture content reaches 12%；
(5) pack: after cooling, sealed package sticks the label containing two-dimentional traceability code.
Embodiment 2
The present invention provides a kind of fresh cutting processing method of Yujin slices, includes the following steps:
(1) it cleans: after fresh Radix Curcumae medicinal material harvesting, using the soil of tumbling-box type medicine-washing machine clean the surface attachment；
(2) fresh Radix Curcumae medicinal material stepping: is divided into 2 grades by transverse diameter size by screening machine；
(3) it is sliced: using microtome, slice thickness 3.0mm；
(4) dry: using the dry medicine materical crude slice of the dry combination method of hot-air seasoning-intermittent type microwave, hot air circulation drying temperature is
60 DEG C, the time is 5 hours；Microwave drying power is 3kW, the interval 1 minute of every drying 2 minutes, until moisture content reaches 12%；
(5) pack: after cooling, sealed package is saved, and sticks the label containing two-dimentional traceability code.
Embodiment 3
The present invention provides a kind of fresh cutting processing method of Yujin slices, includes the following steps:
(1) it cleans: after fresh Radix Curcumae medicinal material harvesting, using the soil of tumbling-box type medicine-washing machine clean the surface attachment；
(2) fresh Radix Curcumae medicinal material stepping: is divided into 3 grades by transverse diameter size by screening machine；
(3) it is sliced: using microtome, slice thickness 4.0mm；
(4) dry: using the dry medicine materical crude slice of the dry combination method of hot-air seasoning-intermittent type microwave, hot air circulation drying temperature is
70 DEG C, the time is 4 hours；Microwave drying power is 4kW, the interval 1 minute of every drying 3 minutes, until moisture content reaches 12%；
(5) pack: after cooling, sealed package sticks the label containing two-dimentional traceability code.
The medicine materical crude slice process time of embodiment 1 to 3, medicine materical crude slice yield and piece shape percentage of head rice are detected, it is as follows
Medicine materical crude slice process time: the time used in the processing overall process packed to medicine materical crude slice is cleaned from fresh Radix Curcumae medicinal material, clearly
Step is washed using 1 hour, stepping step uses 30 minutes, and slicing step uses 1 hour, and packaging (containing cooling) step is small using 2
When.Medicine materical crude slice piece type qualification rate is that shape is intact, meets the slice of " Chinese Pharmacopoeia " (version in 2015) regulation " thin slice " piece type specification
The percentage of total chipping qualities is accounted for, the results are shown in Table 1
Table 1
The above results show that processing method prepares Yujin slices through the invention, and the process-cycle is obviously shortened, labor intensity
It is low, high production efficiency, medicine materical crude slice piece type qualification rate height.
The total volatile oil percentage composition of embodiment 1 to 3 and traditional processing medicine materical crude slice is detected, it is as follows
It measures and compares fresh according to " Chinese Pharmacopoeia " (version in 2015, one) annex " 2204 determination of volatile oil method " first method
Cut processing medicine materical crude slice and traditional processing medicine materical crude slice (medicine materical crude slice is made according to the processing method in background technique in comparative example, same as below)
Middle total volatile oil percentage composition, the results are shown in Table 2
Table 2
The above results show that processing method prepares Yujin slices through the invention, and the percentage composition of total volatile oil is obviously high
In the Yujin slices that traditional processing obtains.
To curdione in embodiment 1 to 3 and traditional processing medicine materical crude slice (comparative example), rcumenol, germacrone, furanodiene,
The content of beta-elemene is detected, and detection method is high performance liquid chromatography, and chromatographic condition is with C18Chromatographic column is stationary phase,
It is eluted by eluent gradient of -0.05% phosphoric acid solution of acetonitrile, Detection wavelength 214nm, flow velocity 1mLmin-1, detected
Journey are as follows:
I. the preparation of reference substance solution takes curdione, rcumenol, germacrone, furanodiene, beta-elemene control respectively
Appropriate product, it is accurately weighed, set in brown measuring bottle, scale dissolved and be settled to methanol, obtain every mL 0.8520mg containing curdione,
The single reference substance deposit of rcumenol 1.025mg, germacrone 0.8480mg, furanodiene 0.9145mg, 2.000 μ L of beta-elemene
Liquid.The accurate above-mentioned stock solution of absorption is set in right amount in 5mL brown measuring bottle respectively, is added methanol dilution to scale, is obtained curdione, curcuma zedoary
Alcohol, germacrone, furanodiene, beta-elemene concentration be respectively 102.2mgL-1、41.00mg·L-1、25.44mg·L-1、
36.58mg·L-1、40.00μL·L-1Mixed reference substance solution；
II. the preparation of test solution takes Yujin slices produced by the present invention, beats powder, crosses No. 4 sieves, takes powder 1.5g, essence
Close weighed, methanol 20mL, close plug is added in precision, and weighing is ultrasonically treated 40min, lets cool, and dries outer wall, close plug, and first is used in weighing
Alcohol supplies the weight of less loss, shakes up, and crosses 0.45 μm of filter membrane, subsequent filtrate is taken to be detected.As a result as shown in Fig. 1 to 5, table 3
Table 3
The above results show that processing method prepares Yujin slices, main active curdione, curcuma zedoary through the invention
Alcohol, germacrone, furanodiene, beta-elemene percentage composition be above the Yujin slices that traditional processing obtains.
The present embodiments relate to the material arrived, reagent and experimental facilities, are to meet Chinese medicine to add unless otherwise instructed
The commercial product in work field.
The above is merely a preferred embodiment of the present invention, it is noted that for those skilled in the art
For, under the premise of not departing from core of the invention technology, improvements and modifications can also be made, these improvements and modifications are also answered
Belong to scope of patent protection of the invention.With any change in the comparable meaning and scope of claims of the present invention, all
It is considered as being included within the scope of the claims.
Claims (7)
1. the fresh cutting processing method of Yujin slices, which is characterized in that by stepping after the cleaning of fresh Radix Curcumae medicinal material, then slice is adopted
Medicine materical crude slice is obtained with the dry combination method of hot-air seasoning-intermittent type microwave is dry.
2. the fresh cutting processing method of Yujin slices as described in claim 1, which is characterized in that the hot-air seasoning to moisture content
For 20%-30%, the intermittent type microwave drying to moisture content 10%-12%.
3. the fresh cutting processing method of Yujin slices as described in claim 1, which is characterized in that the hot-air seasoning temperature is
45-75 DEG C, the time is 3-9 hours；The dry power of the intermittent type microwave is 1-5kW, every dry 1-5 minutes interval 1-3 minutes.
4. the fresh cutting processing method of Yujin slices as described in claim 1, which is characterized in that controlling slice thickness when slice is
1.8-4.2mm。
5. the fresh cutting processing method of Yujin slices as described in claim 1, which is characterized in that the stepping is according to medicinal material cross
Diameter size is divided into 2-3 grades.
6. the fresh cutting processing method of Yujin slices as described in claim 1, which is characterized in that the hot-air seasoning-is intermittent
Include the steps that after the dry medicine materical crude slice of microwave drying combination method it is cooling, it is described to be cooled to cooled to room temperature.
7. the fresh cutting processing method of Yujin slices as described in claim 1, which is characterized in that the cleaning is using drum-type
Medicine-washing machine cleans the soil of medicinal material surface attachment；The stepping is to be sieved by screening machine according to medicinal material transverse diameter.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115501313A (en) * | 2022-10-09 | 2022-12-23 | 四川智佳成生物科技有限公司 | Fresh-producing-place processing method of green-silk curcuma aromatica |
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| CN105056147A (en) * | 2015-08-31 | 2015-11-18 | 徐自升 | Fresh-cut processing technology for radix curcumae |
| CN107375824A (en) * | 2017-06-16 | 2017-11-24 | 康美药业股份有限公司 | A kind of processing method of Yujin slices and the Yujin slices obtained by this method |
| CN107782124A (en) * | 2017-09-15 | 2018-03-09 | 李淑存 | A kind of hot wind and microwave dries conjuncted method |
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2018
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| CN105056147A (en) * | 2015-08-31 | 2015-11-18 | 徐自升 | Fresh-cut processing technology for radix curcumae |
| CN107375824A (en) * | 2017-06-16 | 2017-11-24 | 康美药业股份有限公司 | A kind of processing method of Yujin slices and the Yujin slices obtained by this method |
| CN107782124A (en) * | 2017-09-15 | 2018-03-09 | 李淑存 | A kind of hot wind and microwave dries conjuncted method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115501313A (en) * | 2022-10-09 | 2022-12-23 | 四川智佳成生物科技有限公司 | Fresh-producing-place processing method of green-silk curcuma aromatica |
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