CN107753354A - Anti-aging moisturizing skin care product containing stem cell growth factors and application thereof - Google Patents

Anti-aging moisturizing skin care product containing stem cell growth factors and application thereof Download PDF

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Publication number
CN107753354A
CN107753354A CN201711279691.3A CN201711279691A CN107753354A CN 107753354 A CN107753354 A CN 107753354A CN 201711279691 A CN201711279691 A CN 201711279691A CN 107753354 A CN107753354 A CN 107753354A
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Prior art keywords
stem cell
cell factor
containing stem
aging
aging moisturizer
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CN201711279691.3A
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Inventor
陈海佳
葛啸虎
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Priority to CN201711279691.3A priority Critical patent/CN107753354A/en
Publication of CN107753354A publication Critical patent/CN107753354A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/604Alkylpolyglycosides; Derivatives thereof, e.g. esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the field of skin care products, and particularly relates to an anti-aging moisturizing skin care product containing stem cell growth factors and application thereof. The anti-aging moisturizing skin care product containing the stem cell growth factors comprises the following components: stem cell growth factor, epidermal cell growth factor, oligopeptide-29, dipeptide-4, seaweed extract, calendula extract, shea butter, glycerol, caprylic/capric triglyceride, polydimethylsiloxane, antioxidant, methylglucose sesquistearate, alkyl glycoside, triethanolamine, sodium hyaluronate, thickener and water. The anti-aging moisturizing skin care product containing the stem cell growth factors has the effects of scavenging free radicals, resisting oxidation, reducing swelling, moistening, moisturizing and the like, does not need to add an additional chemical preservative, and is natural, safe and green.

Description

A kind of anti-aging Moisturizer and its application containing stem cell factor
Technical field
The invention belongs to skin care field, and in particular to a kind of anti-aging Moisturizer containing stem cell factor and It is applied.
Background technology
Skin at every moment all slowly reduces in aging, its elasticity, and thins down, more and more fragile and relaxation, The visual impression given people is exactly to be wrinkled.Skin ageing phenomenon is mainly manifested in two aspects:(1) skin histology fails:Skin The thickness of skin has obvious change with the increase at age, most thick during the epidermis of people 20 years old, later gradually thinning, to the senescence phase Granulosa can atrophy to disappear, prickle cell's short survival.Epidermal cell nuclear fission increase, therefore melanin also increases, so that old The colour of skin of people is mostly brownish black.Because aged cells are attached to horny layer of epidermis, skin surface is hardened, tarnish.Corium Most thick at 30 years old, later gradual change is thin and with atrophy.Subcutaneous fat is reduced, and because elastic fibers and collagenous fibres become Change and gradually lose skin elasticity and tension force, further cause cutis laxa to be produced with wrinkle.(2) physiological function is low:Sebaceous glands, Sweat gland deterioration, sweat exclude to reduce with sebum, and skin gradually loses gloss in the past and becomes drying.Blood circulation function subtracts Move back to supplement the necessary nutrition of skin, therefore the refractory conjunction of the elderly's skin wound.
Skin aging is the accumulation of the cell and structural damage that progressively occur with the growth at personal age, skin aging Process be divided into it is inherent and it is external two aspect.Intrinsic procedure refers to the age increase with people, occurs on skin Phenomena such as small microgroove and cutis laxa.The endogenetic mechanisms of skin senescence are extremely complex, more representational causes of senescence master To include free radical theory, theory of genetic gene, mitochondrial DNA damage theory etc..Extrinsic process be often referred to environment or other The exposure of form impacts to skin, and some change caused by.For example there is deeper thicker wrinkle, husking, skin Drying, senile plaque expelling etc..Extrinsic factor mainly includes ultraviolet irradiation, smoke from cigarette and other bad life habits etc..Outside The presence of source sexual factor can accelerate the process of skin natural aging.
Aging is the inexorable law of life process, is inevitable, but anti-aging is possible.With people The continuous improvement of living standard, everybody in terms of also beginning to pay close attention to other after meeting basic clothing, food, lodging and transportion -- basic necessities of life demand, such as from Oneself appearance.With the development of science and technology, anti-aging cosmetics also have been to be concerned by more and more people.
Anti-aging cosmetics can substantially be divided into three classes by its function or effect difference, respectively humidity-preserving type cosmetic, anti- Oxidized form cosmetics and bioactivity cosmetics.Activated feedstock in variety classes cosmetics is different, with to biology The constantly improve of study of active components, the activated feedstock being applied in anti-aging cosmetics are also more and more.By not same-action Activated feedstock can typically be divided into moisturizing class, remove radical type, absorbs ultraviolet class and the species of cell repair class four by mechanism Type.
The content of the invention
For overcome the deficiencies in the prior art and shortcoming, primary and foremost purpose of the invention is that providing one kind contains stem cell growth The anti-aging Moisturizer of the factor.
Another object of the present invention is to provide the preparation of the above-mentioned anti-aging Moisturizer containing stem cell factor Method, this method is simple to operate, and cost is low, suitable for industrialized production.
It is still another object of the present invention to provide the application of the above-mentioned anti-aging Moisturizer containing stem cell factor.
The purpose of the present invention is achieved through the following technical solutions:
A kind of anti-aging Moisturizer containing stem cell factor, includes component as follows in parts by mass:
The described anti-aging Moisturizer containing stem cell factor, preferably comprise following group in parts by mass Point:
Described human stem cell growth is preferably at least one of hSCGF- α and hSCGF- β;
The production specification of described seaweed extracted liquor is preferably 10:1 (ratio extract);
Described pot marigold extract Lutein content is not less than 20%;
Described antioxidant is preferably Tea Polyphenols;
Described thickener is preferably xanthans, carbomer, guar gum and acrylamide dimethyltaurine ammonium/VP copolymerization At least one of thing (AVC);
Described thickener is preferably xanthans, carbomer and acrylamide dimethyltaurine ammonium/VP copolymers (AVC) Mixture;
The mass ratio of described xanthans, carbomer and acrylamide dimethyltaurine ammonium/VP copolymers (AVC) is preferred For 3:1:1;
The preparation method of the described anti-aging Moisturizer containing stem cell factor, is comprised the following steps:
(1) by Butyrospermum parkii fruit fat, caprylic/capric triglyceride, dimethyl silicone polymer, methyl sesquialter stearic acid Ester, APG, triethanolamine are added in oil phase pot, and heating stirring obtains oil phase material to being completely dissolved;
(2) glycerine, Sodium Hyaluronate, thickener and water are mixed, heating stirring obtains aqueous phase material to being completely dissolved;
(3) under stirring, oil phase material is added in aqueous phase material;Then vacuum emulsifying, lotion is obtained;
(4) when lotion made from step (3) is cooled to below 40 DEG C, by remaining ingredient (stem cell factor, epidermis Porcine HGF, oligopeptides -29, dipeptides -4, seaweed extracted liquor, pot marigold extract and antioxidant) it is added in lotion, stir Mix uniformly, obtain the anti-aging Moisturizer containing stem cell factor;
The described anti-aging Moisturizer containing stem cell factor can further filling, packaging;
Described application of the anti-aging Moisturizer in skin care field containing stem cell factor;
The principle of the present invention:
The present invention is by by skin care active ingredient stem cell factor, epithelical cell growth factor, oligopeptides -29 and two Peptide -4 rationally compounds, and different effective active compositions is produced synergistic function, not only to hydroxy radical (OH) and peroxide Change hydrogen (H2O2) there is good Scavenging activity, and collagen and elastin manufacture and increase skin can be promoted anti-oxidant Ability, delay skin aging and other effects.Second, seaweed extracted liquor has moisturizing, thickening, calmness, the function of smooth moisturizing, golden small cup Flower extract has anti-inflammatory, antibacterial action, and both additions cause skin care item moisturizing anti-aging effects further to improve.
The present invention is had the following advantages relative to prior art and effect:
(1) the anti-aging Moisturizer provided by the invention containing stem cell factor, which has, removes free radical, antioxygen Change, subside a swelling, moisten moisturizing and other effects.
(2) present invention is used as using xanthans, carbomer and acrylamide dimethyltaurine ammonium/VP polymer combinations and increased Thick dose so that obtained skin care item stable system.
(3) the anti-aging Moisturizer provided by the invention containing stem cell factor need not add extra chemistry Preservative, naturally, safety, green.
Embodiment
With reference to embodiment, the present invention is described in further detail, but the implementation of the present invention is not limited to this.
Stem cell factor is hSCGF- α in embodiment, purchased from Peprotech companies;The production rule of seaweed extracted liquor Lattice are 10:1, purchased from Guangzhou An Pin Chemical Co., Ltd.s;Pot marigold extract Lutein content is more than 20%, purchased from Xi'an Yuan Sen bio tech ltd;
Embodiment 1
A kind of anti-aging Moisturizer containing stem cell factor, includes component as follows in parts by mass:
The preparation method of the described anti-aging Moisturizer containing stem cell factor, is comprised the following steps:
(1) by Butyrospermum parkii fruit fat, caprylic/capric triglyceride, dimethyl silicone polymer, methyl sesquialter stearic acid Ester, APG, triethanolamine are added in oil phase pot, and 75 DEG C of heating stirrings obtain oil phase material to being completely dissolved;
(2) by glycerine, Sodium Hyaluronate, xanthans, carbomer, AVC and water mix, 75 DEG C of heating stirrings to completely it is molten Solution, obtains aqueous phase material;
(3) 75 DEG C, under stirring, oil phase material is added in aqueous phase material;Then vacuum emulsifying 15min, obtains lotion;
(4) when lotion made from step (3) is cooled to 37 DEG C, by remaining ingredient (stem cell factor, epidermal cell Growth factor, oligopeptides -29, dipeptides -4, seaweed extracted liquor, pot marigold extract and Tea Polyphenols) it is added in lotion, stirring is equal It is even, obtain the anti-aging Moisturizer containing stem cell factor;
(5) the anti-aging Moisturizer containing stem cell factor made from step (4) is further filling, packs, and obtains To anti-aging Moisturizer of the finished product containing stem cell factor.
Embodiment 2
A kind of anti-aging Moisturizer containing stem cell factor, includes component as follows in parts by mass:
The preparation method of the described anti-aging Moisturizer containing stem cell factor, is comprised the following steps:
(1) by Butyrospermum parkii fruit fat, caprylic/capric triglyceride, dimethyl silicone polymer, methyl sesquialter stearic acid Ester, APG, triethanolamine are added in oil phase pot, and 70 DEG C of heating stirrings obtain oil phase material to being completely dissolved;
(2) by glycerine, Sodium Hyaluronate, xanthans, carbomer, AVC and water mix, 70 DEG C of heating stirrings to completely it is molten Solution, obtains aqueous phase material;
(3) 70 DEG C, under stirring, oil phase material is added in aqueous phase material;Then vacuum emulsifying 20min, obtains lotion;
(4) when lotion made from step (3) is cooled to 30 DEG C, by remaining ingredient (stem cell factor, epidermal cell Growth factor, oligopeptides -29, dipeptides -4, seaweed extracted liquor, pot marigold extract and Tea Polyphenols) it is added in lotion, stirring is equal It is even, obtain the anti-aging Moisturizer containing stem cell factor;
(5) the anti-aging Moisturizer containing stem cell factor made from step (4) is further filling, packs, and obtains To anti-aging Moisturizer of the finished product containing stem cell factor.
Embodiment 3
A kind of anti-aging Moisturizer containing stem cell factor, includes component as follows in parts by mass:
The preparation method of the described anti-aging Moisturizer containing stem cell factor, is comprised the following steps:
(1) by Butyrospermum parkii fruit fat, caprylic/capric triglyceride, dimethyl silicone polymer, methyl sesquialter stearic acid Ester, APG, triethanolamine are added in oil phase pot, and 85 DEG C of heating stirrings obtain oil phase material to being completely dissolved;
(2) by glycerine, Sodium Hyaluronate, xanthans, carbomer, AVC and water mix, 85 DEG C of heating stirrings to completely it is molten Solution, obtains aqueous phase material;
(3) 85 DEG C, under stirring, oil phase material is added in aqueous phase material;Then vacuum emulsifying 10min, obtains lotion;
(4) when lotion made from step (3) is cooled to 40 DEG C, by remaining ingredient (stem cell factor, epidermal cell Growth factor, oligopeptides -29, dipeptides -4, seaweed extracted liquor, pot marigold extract and Tea Polyphenols) it is added in lotion, stirring is equal It is even, obtain the anti-aging Moisturizer containing stem cell factor;
(5) the anti-aging Moisturizer containing stem cell factor made from step (4) is further filling, packs, and obtains To anti-aging Moisturizer of the finished product containing stem cell factor.
Comparative example
A kind of skin care item, include component as follows in parts by mass:
The preparation method of described skin care item, is comprised the following steps:
(1) by Butyrospermum parkii fruit fat, caprylic/capric triglyceride, dimethyl silicone polymer, methyl sesquialter stearic acid Ester, APG, triethanolamine are added in oil phase pot, and 75 DEG C of heating stirrings obtain oil phase material to being completely dissolved;
(2) glycerine, Sodium Hyaluronate, xanthans and water are mixed, 75 DEG C of heating stirrings obtain aqueous phase to being completely dissolved Material;
(3) 75 DEG C, under stirring, oil phase material is added in aqueous phase material;Then vacuum emulsifying 15min, obtains lotion;
(4) when lotion made from step (3) is cooled to 37 DEG C, remaining ingredient (Tea Polyphenols) is added in lotion, stirred Mix uniformly, obtain skin care item;
(5) skin care item made from step (4) are further filling, pack, and obtain finished product skin care item.
Effect example
(1) measure of moisture retention
The actual conditions of simulated skin, from appropriately sized glass dish, weigh a certain amount of anti-aging Moisturizer (embodiment 1~3) is re-weighed after drier 24h on glass dish, is put into, calculates percentage of water loss, percentage of water loss is smaller, shows moisturizing Effect is better.Calculation formula is as follows:
Percentage of water loss %=(M1- M2) × 100%/M1
Wherein:M1, the weight of product and surface plate before placement, g;M2, the weight of product and surface plate after placement, g.
Test result shows, compared with comparative example, anti-aging Moisturizer prepared by embodiment 1~3 has more Good performance of keeping humidity.
Anti-aging Moisturizer performance of keeping humidity analysis prepared by the embodiment 1~3 of table 1
Embodiment Embodiment 1 Embodiment 2 Embodiment 3 Comparative example
Percentage of water loss (%) 8.87 9.33 9.06 13.54
(2) radicals scavenging
It is matter that skin care item made from embodiment 1~3 and comparative example are configured into concentration respectively with dimethyl sulfoxide (DMSO) The active ingredient solution of volume ratio 1% is measured, carries out following experiment.
(1) measure of radicals scavenging effect
Take diphenyl picryl phenylhydrazine (DPPH) solution that active ingredient solution 2mL and concentration are 100 μm of ol/L (solution Solvent is for water) 2mL successively add in same tool plug test tube, shake up;At room temperature stand 30 minutes, using solvent as blank in Determination sample absorbance under 517nm wavelength.Inhibiting rate:K%=[1- (Ai-Aj)/Ac] × 100%;Ai:2mL DPPH solution+ The absorbance of 2mL active ingredient solutions;Aj:The absorbance of 2mL active ingredient solution+2mL solvents (i.e. dimethyl sulfoxide (DMSO));Ac: The absorbance of 2mL DPPH solution+2mL solvents (i.e. dimethyl sulfoxide (DMSO)).
2 are the results are shown in Table, there is anti-aging Moisturizer made from embodiment 1~3 preferable radicals scavenging to act on, suppression Rate processed is up to 91.5%.
The measure that anti-aging Moisturizer radicals scavenging made from the embodiment 1~3 of table 2 acts on
Embodiment Inhibiting rate (%)
Embodiment 1 91.5
Embodiment 2 90.2
Embodiment 3 88.7
Comparative example 63.9
Above-described embodiment is the preferable embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment Limitation, other any Spirit Essences without departing from the present invention with made under principle change, modification, replacement, combine, simplification, Equivalent substitute mode is should be, is included within protection scope of the present invention.

Claims (10)

1. a kind of anti-aging Moisturizer containing stem cell factor, it is characterised in that include group as follows in parts by mass Point:
2. the anti-aging Moisturizer according to claim 1 containing stem cell factor, it is characterised in that comprising such as Under component in parts by mass:
3. the anti-aging Moisturizer according to claim 1 or 2 containing stem cell factor, it is characterised in that:
Described human stem cell growth is at least one of hSCGF- α and hSCGF- β.
4. the anti-aging Moisturizer according to claim 1 or 2 containing stem cell factor, it is characterised in that:
Described antioxidant is Tea Polyphenols.
5. the anti-aging Moisturizer according to claim 1 or 2 containing stem cell factor, it is characterised in that:
Described thickener be xanthans, carbomer, guar gum and acrylamide dimethyltaurine ammonium/VP copolymers at least It is a kind of.
6. the anti-aging Moisturizer according to claim 5 containing stem cell factor, it is characterised in that:
Described thickener is the mixture of xanthans, carbomer and acrylamide dimethyltaurine ammonium/VP copolymers.
7. the anti-aging Moisturizer according to claim 6 containing stem cell factor, it is characterised in that:
The mass ratio of described xanthans, carbomer and acrylamide dimethyltaurine ammonium/VP copolymers is 3:1:1.
8. the preparation method of the anti-aging Moisturizer containing stem cell factor described in any one of claim 1~7, its It is characterised by comprising the following steps:
(1) by Butyrospermum parkii fruit fat, caprylic/capric triglyceride, dimethyl silicone polymer, methyl sesquistearate, APG, triethanolamine are added in oil phase pot, and heating stirring obtains oil phase material to being completely dissolved;
(2) glycerine, Sodium Hyaluronate, thickener and water are mixed, heating stirring obtains aqueous phase material to being completely dissolved;
(3) under stirring, oil phase material is added in aqueous phase material;Then vacuum emulsifying, lotion is obtained;
(4) when lotion made from step (3) is cooled to below 40 DEG C, remaining ingredient is added in lotion, stirred, is obtained To the anti-aging Moisturizer containing stem cell factor.
9. the preparation method of the anti-aging Moisturizer according to claim 8 containing stem cell factor, its feature It is:
The described anti-aging Moisturizer containing stem cell factor can further filling, packaging.
10. the anti-aging Moisturizer containing stem cell factor described in any one of claim 1~7 is in skin care field In application.
CN201711279691.3A 2017-12-06 2017-12-06 Anti-aging moisturizing skin care product containing stem cell growth factors and application thereof Withdrawn CN107753354A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108514542A (en) * 2018-05-11 2018-09-11 深圳市旷逸生物科技有限公司 A kind of moisturizing mildy wash and the preparation method and application thereof containing stem cell factor
CN111329789A (en) * 2020-05-06 2020-06-26 陈乾 Anti-aging and moisturizing cosmetic containing stem cell compound factors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EC ATTAR等: "Regulation of hematopoietic stem cell growth", 《LEUKEMIA》 *
中华人民共和国卫生部: "《化妆品卫生规范》", 31 January 2007 *
国家药品监督管理局: "化妆品监督管理常见问题解答(一)", 《国家药品监督管理局官网》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108514542A (en) * 2018-05-11 2018-09-11 深圳市旷逸生物科技有限公司 A kind of moisturizing mildy wash and the preparation method and application thereof containing stem cell factor
CN111329789A (en) * 2020-05-06 2020-06-26 陈乾 Anti-aging and moisturizing cosmetic containing stem cell compound factors
CN111329789B (en) * 2020-05-06 2021-01-29 广州市宙斯生物科技有限责任公司 Preparation method of anti-aging moisturizing cosmetic

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