CN105943427A - Multiple-effect moisturizing eye cream containing peony seed oil and preparation method thereof - Google Patents
Multiple-effect moisturizing eye cream containing peony seed oil and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a multiple-effect moisturizing eye cream containing peony seed oil and a preparation method thereof. The eye cream is prepared from: peony seed oil, sweet almond oil, buckwheat extract, emulsifier, witch hazel distilled fluid, grapefruit extract, apple stem cell, vegetable glycerin, low-molecular-hyaluronic acid, tea polyphenol, antibacterial agent and deionized water. The eye cream can accelerate the blood microcirculation of the skin around eyes, increase the vitality of epidermic cells, enhance the skin elasticity, and can scavenge the free radical effectively, so that the formation of melanin is inhibited and the skin aging is delayed.
Description
Technical field
The invention belongs to daily cosmetics technical field, relate to the cosmetic composition that a kind of multiple-effect is moistened, particularly relate to one
Plant the multiple-effect containing peony seed oil and moisten eye cream and preparation method thereof.
Background technology
Eye skin soft and fine slim (about 0.3mm), sweat gland of skin and sebaceous gland distribution are less, lack moisture and oil point point
Secreting, add that orbitalis muscle often shrinks on ordinary days, collagen tissue easily follows the string, and easily produces microgroove；Evening sleep period
Between eye lack motion, lymphsystem running slow down, be easily caused eyes edema in morning, may eventually form eye pouch；Sleep is not
Foot cause ocular circulation to slow down, be easily generated black eye etc., these all determine eye skin be easiest to aging also
The place come into question.Eye-care product are mainly compacted by eye replenishing water and preserving moisture, lifting, go edema, whitening and resist
Wrinkle mode suppresses or alleviates black eye, eye pouch, and can obviously improve wrinkle, microgroove.Eye-care product are for most people
For be all necessary, especially at some in particular cases, such as seasonal factor, dry skin, long-term computer radiate,
It is exposed to the sun etc., should use early, prevent periocualr skin wrinkle from occurring too early.
At present, commercially available eye-care kind class is a lot, is roughly divided into eye mask, eye glue, eye curry, eye sticker, eye cream
Deng；Functionally it is divided into moist type, compact real form, aging resistance type, anti-allergic etc..But in most products not only hydrargyrum,
Lead, phenol content exceed standard, and can add substantial amounts of thickening agent, such as triethanolamine, card ripple, sodium acrylate/acryloyl two
The materials such as N-methyltaurine sodium copolymer, and EDTA chelating agen, titanium dioxide and the preservative containing Form aldehyde release body,
Although can temporarily make skin present glossy soft state, but that horny layer can be made to come off is thinning for life-time service, causes skin red
Swollen, form mottle, be unfavorable for skin health.And natural plant kind eye cream more comes because it is green, natural, safe, harmless
The most welcomed by the people.
CN101697955A discloses a kind of eye cream adding pearl hydrolysate liposome, and described eye cream is by Margarita hydrolyzed solution
Liposome, cetearyl alcohol, polydimethylsiloxane, butanediol, squalane, PEG-100 stearate, cocoyl
The emulsifying homogeneous such as glucoside, dicaprylyl carbonate, hyaluronic acid, Jojoba oil, caffeine wrappage, vitamin E form.
This product can promote that regenerative cell synthesizes, and improves the blood circulation of eye skin, improves eye skin elastic, reaches to dispel
The black eye of eye, the cosmetic result such as eye pouch and wrinkle, but, the detection in terms of this eye cream moisture retention and other effect
Need to be further improved.
CN103536492A discloses a kind of black eye-resisting eye cream, eye cream by shea butter, Flos Campsis, Fructus Canarii albi liquid,
Radix Ginseng, glycerol, hyaluronic acid, Radix Puerariae oil, vaseline, jasmine hydrosol etc. form, and can make eye rapidly by percutaneous absorption
Portion's skin becomes bright, dispels rapidly the heavy shallow lake of color of eyelet, eye pouch, Vitamin K.But, this facial mask liquid function
Single, it is difficult to tackle the eye skin problem of modern society women comprehensively.
By retrieving domestic and international prior art, the most not yet find the document report utilizing peony seed oil and tea polyphenols to prepare eye cream
Road, the more needleless efficacy detection technology to relevant eye cream.
Summary of the invention
In view of the deficiencies in the prior art, it is an object of the invention to provide a kind of multiple-effect being available for the use of various skin quality and moisten eye
Frost and preparation method thereof, blank to fill up peony seed oil use in prepared by eye cream, solve because of air pollution, radiation,
The various skin problems that the reasons such as fatigue and aging cause.
In order to realize the purpose of the present invention, inventor, by lot of experiments research persistent exploration, is finally obtained such as next
The technical scheme of eye cream kind is moistened containing the multiple-effect of peony seed oil:
A kind of multiple-effect containing peony seed oil moistens eye cream, and described eye cream is prepared from by following component: peony seed oil, sweet
Almond oil, Semen Fagopyri Esculenti extract, emulsifying agent, Radix Hamamelidis Mollis distillate, grapefruit extract, dried apple slices cell, vegetable glycerides,
Low molecule hyaluronic acid, tea polyphenols, antibacterial, deionized water.
Preferably, a kind of multiple-effect containing peony seed oil moistens eye cream, and the weight/mass percentage composition of each component is:
Peony seed oil 1%-10%, Semen pruni armeniacae oil 0.3%-5%, Semen Fagopyri Esculenti extract 0.1%-2%, emulsifying agent 1%-10%, gold thread
Prunus mume (sieb.) sieb.et zucc. distillate 1%-20%, grapefruit extract 0.5%-5%, dried apple slices cell 1%-5%, vegetable glycerides 2%-15%,
Low molecule hyaluronic acid 2%-8%, tea polyphenols 0.8%-6%, antibacterial 0.05%-0.5%, surplus is deionized water.
It is further preferred that a kind of multiple-effect containing peony seed oil moistens eye cream, each component in eye cream therein
Weight/mass percentage composition be: peony seed oil 2.5%, Semen pruni armeniacae oil 0.5%, Semen Fagopyri Esculenti extract 0.5%, emulsifying agent 4%,
Radix Hamamelidis Mollis distillate 5%, grapefruit extract 2%, dried apple slices cell 2%, vegetable glycerides 5%, low molecule hyaluronic acid
5%, tea polyphenols 2.5%, antibacterial 0.05%-0.5%, surplus is deionized water.
The most preferably, a kind of multiple-effect containing peony seed oil moistens eye cream, and emulsifying agent therein is selected from
In C9-15 alcohol phosphate ester, cetearyl alcohol, lauryl alcohol phosphate ester, stearyl alcohol phosphate ester and C20-22 alcohol phosphate ester extremely
Few one.
The most preferably, multiple-effect as above moistens eye cream, and grapefruit extract therein is prepared as follows
Form: with grapefruit as raw material, by supercritical CO2Extraction is prepared from, and detailed process is to flow with 20-50L/h
Speed is passed through carbon dioxide, and adding volumetric concentration by the speed of 1-2L/h is the ethanol of 60%-80%, remains in temperature
30-70 DEG C, pressure be to extract 2-5h under conditions of 7-18MPa；Obtain grapefruit ORGANIC SOLVENT MIXTURES；Put it into again
In decompression low-temperature concentration equipment, it is depressurized to-0.05-0.05MPa, under the conditions of 40-55 DEG C, reclaims organic solvent, obtain Fructus Vitis viniferae
Fructus Citri grandis extract.
The most preferably, multiple-effect as above moistens eye cream, and Radix Hamamelidis Mollis distillate therein is prepared as follows
Form: be 1:2-1:5 according to mass ratio, fresh Radix Hamamelidis Mollis flower mixed with distilled water, distill 3-5h in 80-120 DEG C,
Water layer in recovered oil water separator, obtains Radix Hamamelidis Mollis distillate after filtration.
The most preferably, multiple-effect as above moistens eye cream, Semen Fagopyri Esculenti extract therein be prepared as follows and
Become: Semen Fagopyri Esculenti is crushed, add the ethanol of 15-25 times amount volumetric concentration 60-80%, heating extraction 1-3 time, each 1-2h,
United extraction liquid, is concentrated into the clear paste of density 1.05-1.20g/L, microwave vacuum drying, obtains Semen Fagopyri Esculenti extract.
The most preferably, multiple-effect as above moistens eye cream, antibacterial therein be potassium sorbate or caprylyl glycol with
Pentanediol presses the Compositional antiseptic agent of 1:4 composition.
It addition, present invention also offers a kind of above-mentioned multiple-effect to moisten the preparation method of eye cream, the method comprises the steps:
1) add the peony seed oil of recipe quantity, Semen pruni armeniacae oil, Semen Fagopyri Esculenti extract and emulsifying agent in a reservoir, stir,
It is denoted as solution I, standby；
2) in another container, the deionized water of recipe quantity, Radix Hamamelidis Mollis distillate, grapefruit extract, dried apple slices are added
Cell, vegetable glycerides, low molecule hyaluronic acid and tea polyphenols, stir, and is denoted as solution II, standby；
3) solution II taking full dose 10%-15% adds in solution I, stirring, after there is flocculence material, adds
20%-25% solution II, continues stirring, to paste molding, adds remaining solution II, continue to stir, standby；
4) in step 3) gained paste adds antibacterial, i.e. obtain eye cream after stirring.
It should be noted that the dried apple slices cell that the present invention relates to is conventional commercial product, Mibelle company will be difficult to plant
Kind the endangered Fructus Mali pumilae of Switzerland, after activating with cell training method, then breed in a large number with containers for culturing organisms, its life
Power is strong, is equivalent to the callus cell of plant stem cell.
It addition, find according to antioxygenic property experimental study, contain 2.5% peony seed oil and 2.5% tea polyphenols simultaneously
The non-oxidizability of process 3 be significantly higher than and only add the process 1 without tea polyphenols of 2.5% peony seed oil, and significantly high
In only add 2.5% tea polyphenols without seed of Flos Moutan oil handling 2, peony seed oil and tea polyphenols are added skin protection by this explanation
Time in product, both have the collaborative effect removing skin histology excessive free radicals, make the non-oxidizability of product obtain significance
Improve.The invention provides two kinds of specific components by a certain percentage associated with new opplication, it may be assumed that peony seed oil and tea polyphenols exist
The application in skin histology in the skin care item of excessive free radicals is removed in preparation；Or peony seed oil and tea polyphenols are preparing antioxygen
Application in the property changed skin care item；Wherein peony seed oil is 0.5-20:1, preferably 1-5:1 with the weight ratio of tea polyphenols.Enter one
Preferably, described skin care item are peony seed oil eye cream to step.
Compared with prior art, peony seed oil, Semen pruni armeniacae oil, Semen Fagopyri Esculenti extract, emulsifying agent, Radix Hamamelidis Mollis are steamed by the present invention
The materials such as distillate, grapefruit extract and dried apple slices cell are mixed to form a kind of multiple-effect and moisten antioxidation eye cream, accelerate near the eyes
Skin blood microcirculation, adds the vigor of epidermis cell, increases elasticity of skin, play lifting of compacting, wrinkle resistant defying age,
The effect of beauty face-whitening-nourishing.Therefore, the multiple-effect that the present invention relates to is moistened eye cream and is had the advantages that
1) this eye cream is applicable to the skin of any skin quality, causes due to reasons such as air pollution, operating pressure or agings
Skin around the eyes be dried, microgroove, eye pouch and black eye etc. have and preferably alleviate and inhibitory action；
2) formula adds high-quality moisturizing ingredient, it is possible to intensive moisturizing, the lasting of holding skin around the eyes moisten；
4) peony seed oil has synergism with the multiple active skull cap components in tea polyphenols, can be with anti-lipid peroxidation
The carrying out of effect, effectively removes free radical, thus suppresses melanic formation delay skin aging process；
5) in this eye cream, active component enriches, and not only contains small-molecule substance but also contain macromolecular substances, and small-molecule substance can
With deeply to basal layer, skin corium, there is more sturdy and long-range effect for anti-ageing, consolidation.And macromole, Ke Yiting
Stay epidermal area, observe moisture.Life-time service, will be by interior nourishing, reparation flesh floor cells, from outer radioprotective, antioxidation,
Inside and outside maintenance eye skin, allow double pupil persistently moisten compact, vibrant.
6) being used in combination of peony seed oil and tea polyphenols, by the basis of guaranteeing the quality of product, substantially reduces raw material
Interpolation, thus purchasing of raw materials expense is greatly reduced, and the operability of this formula is extremely strong, is very suitable for factory and criticizes
Quantify to produce.
Accompanying drawing explanation
Fig. 1 is the moisturizing rate curve chart nourishing defying age peony seed oil eye cream of embodiment 4 preparation；
Fig. 2 is the variable concentrations Vc impact on DPPH free radical scavenging power.A: different Vc final concentrations and DPPH in reactant liquor
The curve chart of clearance rate；B: different Vc final concentrations and the curve chart of DPPH clearance rate/0.1mg/mL Vc in reactant liquor；
Fig. 3 is the different disposal eye cream block diagram to DPPH clearance rate effect in embodiment 4.
Detailed description of the invention
Technical scheme and technique effect are only described further by the following examples, and limit never in any form
The present invention processed.The part by weight of the raw material being previously mentioned in embodiment can make the appropriate adjustments.
Embodiment 1: the preparation of grapefruit extract
With grapefruit as raw material, by supercritical CO2Extraction is prepared from, and detailed process is for be passed through with 35L/h flow velocity
Carbon dioxide, by 1.5L/h speed add volumetric concentration be the ethanol of 70%, temperature remain 30-70 DEG C, pressure be
2-5h is extracted under conditions of 7-18MPa；Obtain grapefruit ORGANIC SOLVENT MIXTURES；Put it into decompression low-temperature concentration equipment again
In, it is depressurized to-0.05-0.05MPa, under the conditions of 40-55 DEG C, reclaims organic solvent, obtain grapefruit extract (for eye
The preparation of frost).
Embodiment 2: the preparation of Radix Hamamelidis Mollis distillate
Optimal harvest time Radix Hamamelidis Mollis gathers its flower piece, feeds, be 1:4 according to mass ratio after cleaning, by fresh gold thread
Flos Mume piece mixes with distilled water, distills 3h, the water layer in recovered oil water separator in 100 DEG C, obtains Radix Hamamelidis Mollis after filtration
Distillate (for the preparation of eye cream).
Embodiment 3: the preparation of Semen Fagopyri Esculenti extract
Dry Semen Fagopyri Esculenti is crushed, adds the ethanol solution of 15 times amount volumetric concentrations 70%, heating extraction 3 times, carry for the first time
Take 2h, second time and third time and all extract 1h, united extraction liquid, be concentrated into the clear paste of density 1.15-1.20g/L, microwave
Vacuum drying, obtains Semen Fagopyri Esculenti extract (for the preparation of eye cream).
Embodiment 4: multiple-effect moistens the preparation of eye cream
A kind of multiple-effect containing peony seed oil moistens eye cream, and its component and the weight percentage of each component thereof are shown in Table 1: male
Red seed oil 2.5%, Semen pruni armeniacae oil 0.5%, Semen Fagopyri Esculenti extract 0.5%, emulsifying agent 4%, Radix Hamamelidis Mollis distillate 5%, grapefruit
Extract 5%, dried apple slices cell 2%, vegetable glycerides 5%, low molecule hyaluronic acid 5%, tea polyphenols 2.5%, antibacterial 0.2%,
The table 1 multiple-effect containing peony seed oil moistens eye cream formula 1
Preparation method is as follows:
1) carry out vessel sterilization with the ethanol of 75%, or carry out disinfection with ultraviolet irradiation 30min；
2) in the beaker of 100mL, peony seed oil 2.5g, Semen pruni armeniacae oil 0.5g, Semen Fagopyri Esculenti extract 0.5g, spermaceti are added
Stearyl alcohol 4g, stirs, and is denoted as solution I, standby；
3) in another beaker, Radix Hamamelidis Mollis distillate 5g, grapefruit extract 2g, dried apple slices cell 2g, plant are added sweet
Oil 5g, low molecule hyaluronic acid 5g, tea polyphenols 2.5g and distilled water, stir, be denoted as solution II, standby；
4) take 10mL solution II and add in full dose solution I, stir 4-5min, after causing flocculence material occurs, add
20mL solution II, continues stirring 5min, cream basic forming, adds remaining solution II, continue to stir, standby
With；
5) in step 4) gained cream adds antibacterial, i.e. obtain eye cream after stirring.
Embodiment 5: multiple-effect moistens the preparation of eye cream
A kind of moistening eye cream containing multiple-effect, its component and the weight percentage of each component thereof are shown in Table 2:
The table 2 multiple-effect containing peony seed oil moistens eye cream formula 2
After the part by weight of raw material makes the appropriate adjustments, prepare eye cream according to embodiment 4 preparation method.
Embodiment 6: multiple-effect moistens the preparation of eye cream
A kind of multiple-effect containing peony seed oil moistens eye cream, its component and the weight percentage such as table 3 below of each component thereof:
The table 3 multiple-effect containing peony seed oil moistens eye cream formula 3
After the part by weight of raw material makes the appropriate adjustments, prepare eye cream according to embodiment 4 preparation method.
Embodiment 7: product apparent property is observed
The multiple-effect selecting embodiment 4 preparation moistens eye cream, and observes its apparent index, result such as table 4, and result shows: produce
Product are that brown exquisiteness creamy substance, abnormal smells from the patient and stability are preferable, and pH value is 5.5, belongs to faintly acid, is especially suitable for east
Application on human skin (mean ph value is about 5.8), can make skin be in optimal alimentation state.
The multiple-effect of table 4 embodiment 4 preparation moistens the Apparent character of eye cream
Embodiment 8: product moisture retention determination test
The multiple-effect selecting embodiment 4 preparation moistens eye cream, and tests its moisture retention.According to " 4 kinds of seashells such as Deng Yiqing
Polyose extraction and moisture retention research " method in document, slightly modified, specific as follows: to use silica gel drier, environment
Temperature is 20 DEG C.Take the eye cream 1mL containing 2.5% peony seed oil and 2.5% tea polyphenols to be placed in EP pipe, accurate weighing its
Quality is denoted as H0, be placed in exsiccator, place 1,2,3,4,5,6,7, again weigh after 23h, be denoted as Hn,
Moisturizing rate computing formula is as follows: moisturizing rate (%)=Hn/H0× 100%, in formula: H0For sample containing water quality, HnFor putting
After putting n h, sample is containing water quality.
Experimental result is added up as shown in Figure 1.It will be seen from figure 1 that the moisture retention of this kind of facial mask liquid is after 7h, remain able to
Reaching 99.6%, after 23h, moisturizing rate is also up to 98.5%, and moisture retention is far above " moisture-absorbing moisture-keepings of laminine such as Kong Hexin
Property and dynamics research " wetting agent L-lysine hydrochloride conventional in the skin protection product mentioned in document (moisturizing rate:
87.6%) and glycerol (moisturizing rate: 96%).
Embodiment 9: the product determination test to tyrosinase inhibitory action
The multiple-effect selecting embodiment 4 preparation moistens eye cream, and tests its whitening function.With reference to Wang Jianhua and Lei Fan " 20 kinds
The Chinese medicine research to tyrosinase inhibitory action " method mentioned in document, slightly modified, as follows: to take 1.5mL
Phosphate buffer (0.01M, pH7.2) and the mixed liquor of the tryrosinase of 0.5mL 100u, be denoted as " comparison "；Take
1.5mL sample liquid and the mixed liquor of the tryrosinase of 0.5mL 100u, be denoted as " sample "；After 37 DEG C hatch 10min,
It is separately added into 3mmol L-1Dopa reaction liquid 1mL, continue hatch 2min at 37 DEG C, with phosphate buffer (0.01M,
PH7.2) as blank, at 475nm, absorbance A is measuredComparisonAnd ASample, inhibitory activity against tyrosinase is calculated as follows:
Suppression ratio (%)=(1-ASample/AComparison)×100.Suppression ratio shows that the most greatly whitening capability is the strongest, with vitamin c (Vitamin c,
Vc) as standard specimen.Result shows that the tyrosinase inhibition rate of this product is up to 97.00% ± 0.03%, i.e. this product energy
Enough effective activity suppressing tryrosinase, suppression dopa oxidase becomes DOPA quinone, and stops DOPA quinone to be oxidized to black further
Pigment, thus reach the effect of whitening and speckle dispelling.
Embodiment 10: product non-oxidizability determination test
For more fully assessing whether peony seed oil and tea polyphenols exist synergism, introduce Vc as comparison, research difference
The impact on DPPH clearance rate of concentration Vc；Design 3 process, only add 2.5% peony seed oil (processing 1), only add
2.5% tea polyphenols (process 2) and add 2.5% peony seed oil and 2.5% tea polyphenols (processing 3), research different disposal pair
The diversity of DPPH clearance rate.With reference to " Antioxidative properties of xanthan on the such as Shimada
Autoxidation of soybean oil in cyclodextrin " method mentioned in document, slightly modified, specific as follows: to take
20 μ L sample solution add in EP pipe, add people 3mL0.5mmol L-1DPPH ethanol solution, lucifuge is black at room temperature
Dark place reaction 30min, observes the change of its color, determines have the ascorbic of identical antioxidation according to this color
Concentration.Take 20 μ L Vc solution to add in EP pipe, add people 3mL0.5mmol L-1DPPH ethanol solution；Take 20 μ L70%
Ethanol solution add in EP pipe, add people 3mL0.5mmol L-1DPPH ethanol solution, lucifuge is in dark at room temperature
Place's reaction 30min, the ethanol solution using 70%, as blank, measures absorbance (A at 520nm520), remember respectively
Make ASampleAnd AComparison.Each concentration is repeated 3 times tests to ensure the accuracy of experimental result, finally averages as matching
Data.DPPH clearance rate computing formula is as follows: DPPH clearance rate (%)=(1-ASample/AComparison)×100.Color is the most shallow, DPPH
Clearance rate is the highest, and non-oxidizability is the strongest.
As can be seen from Figure 2A: when in reactant liquor, DPPH concentration is 20mg/mL, and in reactant liquor, Vc final concentration is more than
When 0.1mg/mL is less than 0.35mg/mL, with the increase of Vc concentration, significance strengthens DPPH clearance rate, both it
Between linear relationship can represent with y=18.781x+7.2283, R2=0.9571.When Vc concentration is more than 0.35
During mg/mL, although with the increase of Vc concentration, the clearance rate of DPPH also can increase, but there is not significant difference,
Lie substantially in plateau, to the clearance rate of DPPH all more than 90%.Fig. 2 B shows: when in reactant liquor, Vc is whole
When concentration is less than 0.35mg/mL more than 0.1mg/mL, the DPPH clearance rate of the Vc of average every 0.1mg/mL is
26.83%, and along with the increase of concentration, its non-oxidizability is steady ascendant trend；Excessive concentration or too low time, the most often
The DPPH clearance rate of the Vc of 0.1mg/mL substantially reduces (average out to 5.39%), and when Vc concentration is higher than 0.35mg/mL
Time, DPPH clearance rate is with concentration linearly downward trend.Result above fully shows that the height of antioxidation degree is not
The simple addition of Antioxidative Factors pitch-based sphere, but there is increasingly complex relation, need to carry out Comprehensive Assessment；Evaluate
The height of product non-oxidizability is not to the simple addition of the clearance rate of its DPPH during each Antioxidative Factors independent role,
And it is intended to detect whether its antioxygen rate time each Antioxidative Factors is used in combination in product reaches more than 90%.
In conjunction with information above, analyzing the difference (see Fig. 3) of DPPH clearance rate under the conditions of 3 different disposal, result shows
Show: non-oxidizability (85.70%) significance of process 2 is higher than the non-oxidizability of process 1 (48.46%)；Process 3
Non-oxidizability (90.63%) significance, higher than processing 1 and processing the non-oxidizability of 2, reaches more than 90%, in conjunction with different
Relation between concentration Vc and non-oxidizability it can be seen that now the non-oxidizability of product reached plateau, i.e. it resists
Oxidisability and peony seed oil and the consumption the most linearly dependency relation of tea polyphenols, therefore, it is judged that whether exist collaborative between 2
Effect, should not see whether the DPPH clearance rate processing 3 exceedes process 1 and process 2 sums, but see whether it exceedes
90%, it is obvious that can carry out effective synergism between peony seed oil and tea polyphenols, significance improves eye cream to DPPH
The clearance rate of free radical, thus effectively strengthen the non-oxidizability of product.
Embodiment 11: product beta test is tested
The multiple-effect selecting embodiment 4 preparation moistens eye cream, tests its trial effect.Eye cream is given 30 ages 20 to
The Ms of 50 years old tries out, it is stipulated that the most each use 1 time every day, fills in trial effect feedback form after 4 weeks on probation.Trial effect
Statistics is as shown in table 5:
The multiple-effect of table 5 embodiment 4 preparation moistens the trial state of eye cream
Claims (10)
1. the multiple-effect containing peony seed oil moistens eye cream, it is characterized in that, this eye cream is prepared from by following component: peony seed oil, Semen pruni armeniacae oil, Semen Fagopyri Esculenti extract, emulsifying agent, Radix Hamamelidis Mollis distillate, grapefruit extract, dried apple slices cell, vegetable glycerides, low molecule hyaluronic acid, tea polyphenols, antibacterial, deionized water.
2. moisten eye cream according to the multiple-effect containing peony seed oil described in claim 1, it is characterized in that, in described eye cream, the weight/mass percentage composition of each component is: peony seed oil 1%-10%, Semen pruni armeniacae oil 0.3%-5%, Semen Fagopyri Esculenti extract 0.1%-2%, emulsifying agent 1%-10%, Radix Hamamelidis Mollis distillate 1%-20%, grapefruit extract 0.5%-5%, dried apple slices cell 1%-5%, vegetable glycerides 2%-15%, low molecule hyaluronic acid 2%-8%, tea polyphenols 0.8%-6%, antibacterial 0.05%-0.5%, and surplus is deionized water.
3. moisten eye cream according to the multiple-effect containing peony seed oil described in claim 2, it is characterized in that, in eye cream, the weight/mass percentage composition of each component is: peony seed oil 2.5%, Semen pruni armeniacae oil 0.5%, Semen Fagopyri Esculenti extract 0.5%, emulsifying agent 4%, Radix Hamamelidis Mollis distillate 5%, grapefruit extract 2%, dried apple slices cell 2%, vegetable glycerides 5%, low molecule hyaluronic acid 5%, tea polyphenols 2.5%, antibacterial 0.05%-0.5%, and surplus is deionized water.
4. moisten eye cream according to the multiple-effect containing peony seed oil described in claim 1 or 2 or 3, it is characterized in that, at least one in stearyl alcohol phosphate ester, cetearyl alcohol, C9-15 alcohol phosphate ester, lauryl alcohol phosphate ester and C20-22 alcohol phosphate ester of described emulsifying agent.
5. moisten eye cream according to the multiple-effect containing peony seed oil described in claim 1 or 2 or 3, it is characterized in that, described grapefruit extract is prepared as follows forming: takes grapefruit and adds in extraction kettle, it is passed through carbon dioxide with 20-50 L/h flow velocity, adding volumetric concentration by the speed of 1-2 L/h is the ethanol of 60%-80%, temperature remain 30-70 DEG C, pressure be 7-18 MPa under conditions of extract 2-5 h, obtain grapefruit ORGANIC SOLVENT MIXTURES；Put it into again in decompression low-temperature concentration equipment, be depressurized to-0.05 ~ 0.05 MPa, under the conditions of 40-55 DEG C, reclaim organic solvent, obtain grapefruit extract.
6. moisten eye cream according to the multiple-effect containing peony seed oil described in claim 1 or 2 or 3, it is characterized in that, described Radix Hamamelidis Mollis distillate is prepared as follows forming: be 1:2-1:5 according to mass ratio, fresh Radix Hamamelidis Mollis flower is mixed with distilled water, 3-5 h is distilled in 80-120 DEG C, water layer in recovered oil water separator, obtains Radix Hamamelidis Mollis distillate after filtration.
7. moisten eye cream according to the multiple-effect containing peony seed oil described in claim 1 or 2 or 3, it is characterized in that, described Semen Fagopyri Esculenti extract is prepared as follows forming: crushed by Semen Fagopyri Esculenti, add the ethanol of 15-25 times amount volumetric concentration 60-80%, heating extraction 1-3 time, each 1-2h, united extraction liquid, it is concentrated into the clear paste of density 1.05-1.20 g/L, microwave vacuum drying, obtains Semen Fagopyri Esculenti extract.
8. the preparation method moistening eye cream according to the multiple-effect containing peony seed oil described in claim 1 or 2 or 3, it is characterised in that the method comprises the steps:
1) add the peony seed oil of recipe quantity, Semen pruni armeniacae oil, Semen Fagopyri Esculenti extract and emulsifying agent in a reservoir, stir, be denoted as solution I, standby；
2) in another container, add the deionized water of recipe quantity, Radix Hamamelidis Mollis distillate, grapefruit extract, dried apple slices cell, vegetable glycerides, low molecule hyaluronic acid and tea polyphenols, stir, be denoted as solution II, standby；
3) solution II taking full dose 10%-15% adds in solution I, stirs to after there is flocculence material, adds 20%-25% solution II, continues stirring to paste molding, adds remaining solution II, continue to stir, standby；
4) in step 3) gained paste, add antibacterial, after stirring, i.e. obtain eye cream.
9. peony seed oil and the tea polyphenols application in the eye cream of excessive free radicals in skin histology is removed in preparation, wherein peony seed oil is 0.5-20:1, preferably 1-5:1 with the weight ratio of tea polyphenols.
10. peony seed oil and the tea polyphenols application in preparation non-oxidizability eye cream, wherein peony seed oil is 0.5-20:1, preferably 1-5:1 with the weight ratio of tea polyphenols.
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| CN107049827A (en) * | 2017-05-02 | 2017-08-18 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of anti-wrinkle eye cream |
| CN107811959A (en) * | 2017-10-31 | 2018-03-20 | 广州赛莱拉干细胞科技股份有限公司 | A kind of radiation protection skincare product of the cell extract containing banana figs and preparation method thereof |
| CN107875062A (en) * | 2017-11-30 | 2018-04-06 | 广州赛莱拉干细胞科技股份有限公司 | A kind of antioxidant composition and the skin care item containing said composition |
| CN108308601A (en) * | 2018-01-24 | 2018-07-24 | 江苏神华药业有限公司 | A kind of hyaluronic acid ferment drink and preparation method thereof |
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| CN107049827A (en) * | 2017-05-02 | 2017-08-18 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of anti-wrinkle eye cream |
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| CN107875062A (en) * | 2017-11-30 | 2018-04-06 | 广州赛莱拉干细胞科技股份有限公司 | A kind of antioxidant composition and the skin care item containing said composition |
| CN108308601A (en) * | 2018-01-24 | 2018-07-24 | 江苏神华药业有限公司 | A kind of hyaluronic acid ferment drink and preparation method thereof |
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| CN105943427B (en) | 2018-09-04 |
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Effective date of registration: 20191028 Address after: Qing Ling Xiang Hubei city of Wuhan province Hongshan Zhangjiawan 430065 Special District No. 1 Patentee after: Wuhan Academy of Agricultural Sciences Address before: 430075 Hubei Province, Wuhan city Hongshan District Shanluo Guan Yu Road Road No. 38 Patentee before: FRUIT TREE RESEARCH INSTITUTE OF FORESTRY SCIENCE, WUHAN ACADEMY OF AGRICULTURAL SCIENCE & TECHNOLOGY |