CN107753333B - A kind of essence that moisturizing is releived dew and preparation method thereof - Google Patents

A kind of essence that moisturizing is releived dew and preparation method thereof Download PDF

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CN107753333B
CN107753333B CN201711013365.8A CN201711013365A CN107753333B CN 107753333 B CN107753333 B CN 107753333B CN 201711013365 A CN201711013365 A CN 201711013365A CN 107753333 B CN107753333 B CN 107753333B
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essence
dew
extract
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CN107753333A (en
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何廷刚
朱思阳
艾勇
黄垂凡
张智婷
艾艳
夏菲
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HUA AN TANG BIOTECH GROUP Co.,Ltd.
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Guangzhou Heji Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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Abstract

The invention belongs to cosmetic technical fields, more particularly to a kind of essence that moisturizing is releived dew and preparation method thereof, essence dew is prepared by following raw materials: purslane extract, dried tremella extract and glycine betaine, contain the purslane extract of high-content in the cosmetics, to guarantee that there is cosmetics moisturizing to releive effect, studies have shown that cosmetics of the present invention have good stability, there is good moisture-keeping function for Skin Cell.

Description

A kind of essence that moisturizing is releived dew and preparation method thereof
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of essence that moisturizing is releived dew and preparation method thereof.
Background technique
The skin of people divides epidermis, corium and subcutaneous fat.The outermost layer of epidermis is cuticula, due to cuticula itself The work of natural moisturizing factor, that is, amino acids, lactate and carbohydrate contained in water suction, barrier function and cuticula etc. With making cuticula keep certain water content, maintain the wet of skin.And the appearance of skin and the moisture content of cuticula have It closes, normal keratoderma usually contains the moisture of 10%-30%, to maintain the softness and elasticity of skin.But with the age Growth, keratoderma moisture content can gradually decrease, and when the moisture content of keratoderma is lower than 10%, and skin is just It will appear dry, tight, coarse and furfur etc..In general, cause the unbalanced internal and external condition of skin natural moisture preserving structure Mainly have: 1, as the increasing at age, skin aging, moisture-keeping function and barrier function gradually weaken, natural moisturizing factor content It reduces.2, dry cold weather, humidity is lower, such as autumn and winter.3, certain cutaneous lesions, such as psoriasis, ichthyosis 4, ring The organic solvents such as border and chemical factor, such as washing powder, soap, dish washing liquid detergent and wine and prolonged air conditioner surroundings Deng.5, diet sleep habit, such as partial eclipse, drinking-water less, insomnia.Above-mentioned various reasons cause the skin of people to occur water shortage for a long time Symptom, and then cause more skin problems, such as long spot, small pox, wrinkle, relaxation, therefore be most basic to skin moisture-keeping Skin care step.
It a kind of is of great significance with the releive cosmetics of effect of moisturizing in conclusion researching and developing.
Summary of the invention
For these reasons, applicant has found a kind of new cosmetics, contains in the cosmetics containing height by studying for many years The purslane extract of amount, to guarantee that there is cosmetics moisturizing to releive effect after being combined with other compositions, studies have shown that this hair Bright cosmetics have good stability, have good moisture-keeping function for Skin Cell.
What the present invention was achieved through the following technical solutions.
A kind of moisturizing is releived essence dew, and essence dew is prepared by following raw materials: purslane extract, dried tremella extract And glycine betaine.
Essence dew is prepared by following raw materials: purslane extract 15-20 parts by weight, 0.001 weight of dried tremella extract Measure part, glycine betaine 0.4-0.6 parts by weight.
Essence dew is prepared by following raw materials: purslane extract, dried tremella extract, glycine betaine, hydroxy ethyl fiber Plain, polyacrylic acid grafted starch, EDTA- disodium, tocopherol, trehalose, Sodium Hyaluronate, dipotassium glycyrrhizinate, beta glucan, Silver.
Essence dew is prepared by following raw materials: water, hydroxyethyl cellulose, polyacrylic acid grafted starch, glycerol, 1,3- Butanediol, glycine betaine, isoprene, 1,2- hexylene glycol, EDTA- disodium, Cremophor RH40, olive oil PEG-7 esters, Tocopherol, octyl dodecanol, dried tremella extract, purslane extract, trehalose, Sodium Hyaluronate, dipotassium glycyrrhizinate, β-Portugal are poly- Sugar, silver.
Essence dew is prepared by following raw materials: water 65-70 parts by weight, are gathered at hydroxyethyl cellulose 0.2-0.4 parts by weight Acrylic acid grafted starch 0.10-0.20 parts by weight, glycerol 2-4 parts by weight, 1,3-BDO 5-8 parts by weight, glycine betaine 0.4-0.6 Parts by weight, isoprene 1.5-2.5 parts by weight, 1,2- hexylene glycol 0.4-0.6 parts by weight, EDTA- disodium 0.04-0.06 weight Part, Cremophor RH40 0.25-0.35 parts by weight, olive oil PEG-7 esters 0.25-0.35 parts by weight, tocopherol 0.08- 0.12 parts by weight, octyl dodecanol 0.08-0.12 parts by weight, 0.001 parts by weight of dried tremella extract, purslane extract 15-20 Parts by weight, trehalose 0.08-0.12 parts by weight, Sodium Hyaluronate 0.004-0.006 parts by weight, dipotassium glycyrrhizinate 0.04-0.06 Parts by weight, beta glucan 0.05-0.15 parts by weight, silver 0.1-0.3 parts by weight.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
A kind of moisturizing is releived essence dew, the application being in cosmetics that skin moisture-keeping, skin are releived.
Raw material of the present invention is purchased from and is shown in Table 1:
The raw material sources of the present invention of table 1
Raw material Purchased from producer Date of manufacture
Hydroxyethyl cellulose U.S. Ya Shilan 2016.04.03
Polyacrylic acid grafted starch Daito Kasei Kogyo 2015.12.06
Glycerol Cocoanut tree Acidchem 2016.08.09
1,3-BDO Japan DAICEL 2017.01.08
Glycine betaine Asahi Chemical Industry Asahi Kasel 2016.04.03
Isoprene Japan Kuraray 2016.05.10
1,2- hexylene glycol Symrise 2016.02.18
EDTA- disodium Aksu AKZO NOBEL 2016.01.19
Cremophor RH40 German BASF 2016.11.23
Olive oil PEG-7 esters Taiwan CORUM 2015.12.24
Tocopherol Zhejiang YIYAO 2017.03.05
Purslane extract Guangzhou standing grain base 2016.09.08
Trehalose Japanese woods is former 2016.05.04
Sodium Hyaluronate The prosperous Fu Ruida of China 2017.02.23
Dipotassium glycyrrhizinate Gansu Qinghai Lake medicine company 2016.10.21
Beta glucan Korea Macrocare Tech 2015.11.29
Silver The Japan longevity chamber of commerce 2017.05.08
Specific embodiment
Below the technical scheme of the invention is illustrated by a specific example, but the scope of the present invention is not limited thereto.
Content described in this specification embodiment is only enumerating to the way of realization of inventive concept, protection of the invention Range should not be construed as being limited to the specific forms stated in the embodiments, and protection scope of the present invention is also and in art technology Personnel conceive according to the present invention it is conceivable that equivalent technologies mean.Although embodiment of the invention below is retouched It states, but the invention is not limited to above-mentioned specific embodiments and applications field, following specific embodiments is only to show It is meaning property, guiding, rather than it is restrictive.Those skilled in the art under the enlightenment of this specification and are not taking off In the case where the range protected from the claims in the present invention, a variety of forms can also be made, these belong to the present invention The column of protection.
The following tests of the present invention are on the basis of multiple creative test, with the claimed technical solution of the present invention Based on, the conclusive test of the research staff of summary.
Test 1
Moisturizing experimental study
Test 1 group: water 67mg, hydroxyethyl cellulose 0.3mg, polyacrylic acid grafted starch 0.15mg, glycerol 3mg, 1,3- Butanediol 6.5mg, glycine betaine 0.5mg, isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodium 0.05mg, PEG-40 Rilanit special 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, tremella extract Object 0.001mg, purslane extract 17.5mg, trehalose 0.10mg, Sodium Hyaluronate 0.005mg, dipotassium glycyrrhizinate 0.05mg, Beta glucan 0.30mg, silver 0.20mg.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Test 2 groups: water 67mg, hydroxyethyl cellulose 0.3mg, polyacrylic acid grafted starch 0.15mg, glycerol 3mg, 1,3- Butanediol 6.5mg, glycine betaine 0.5mg, isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodium 0.05mg, PEG-40 Rilanit special 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, tremella extract Object 0.001mg, purslane extract 0.005mg, trehalose 0.10mg, Sodium Hyaluronate 17.5mg, dipotassium glycyrrhizinate 0.05mg, Beta glucan 0.30mg, silver 0.20mg.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Test method: Sodium Hyaluronate (cosmetics-stage);Ammonium sulfate and discoloration silica gel;MTT;Cell culture medium: contain The MEM culture medium of 10% calf serum (PAA), 100U/ml penicillin and 100U/ml streptomysin;0.25% pancreatin;Cell people's table Cornu cutaneum cell plastid strain HaCat;
When epidermal growth to fusion rate is up to 80% or more, the MEM culture medium without calf serum is added and synchronizes Change processing 12h, collected by trypsinisation adjusts cell concentration after counting, is seeded to 24 well culture plates.After cell is adherent, it is added Prepared 1000 μ g/ml of test group cosmetics is diluted with culture medium in advance, is incubated for, positive control is Sodium Hyaluronate (1000μg/ml).After for 24 hours, it is placed in super-clean bench under certain wind speed after being dried, fresh culture is added, continues to train It supports for 24 hours, carries out MTT measurement.Using without any processing group as blank control group in experiment.It is dry that cell is calculated as follows The death rate (%) and protection ratio (%).
The cell dry death rate (%)=(1- detection group OD value/normal group OD value) × 100%
Protection ratio (%)=(the dry death rate of the dry death rate-test group cell of blank group cell)/blank group cell is dry The dry death rate × 100%
Test result: it is shown in Table 1.
The comparison of 1 each group epidermal cell of the table dry death rate and protection ratio
Note: P < 0.05 * * P < 0.01, * compared with blank group.
Conclusion (of pressure testing): it is found that positive controls are shown preferably carefully to epidermal cell dry-run protection experimental study Born of the same parents' protective effect, and test group of the present invention also has good cytoprotection, purslane extract is substituted for same Sodium Hyaluronate (2 groups of test), declines cytoprotection, further proves, essence dew of the present invention can significantly be resisted dry The dry damage to epidermal cell reduces the dry influence to cell viability, has good moisture-keeping function.
Test 2
Heat resistant test
Test 1 group: water 67mg, hydroxyethyl cellulose 0.3mg, polyacrylic acid grafted starch 0.15mg, glycerol 3mg, 1,3- Butanediol 6.5mg, glycine betaine 0.5mg, isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodium 0.05mg, PEG-40 Rilanit special 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, tremella extract Object 0.001mg, purslane extract 17.5mg, trehalose 0.10mg, Sodium Hyaluronate 0.005mg, dipotassium glycyrrhizinate 0.05mg, Beta glucan 0.30mg, silver 0.20mg.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Test 2 groups: water 67mg, hydroxyethyl cellulose 0.3mg, glycerol 3mg, 1,3-BDO 6.5mg, glycine betaine 0.5mg, Isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodium 0.05mg, Cremophor RH40 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, dried tremella extract 0.001mg, purslane extract 17.5mg, trehalose 0.10mg, Sodium Hyaluronate 0.005mg, dipotassium glycyrrhizinate 0.05mg, beta glucan 0.30mg, silver 0.20mg。
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, EDTA bis- Sodium, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.Test method: by different essence The plastic drug package of 2 bottles of clean dries is added in dew, tightens lid, and one bottle is put into and has been pre-adjusted the constant temperature that temperature is 48 ± 1 DEG C It in case, is taken out after 48 hours, after recovery room temperature compared with another bottle carries out range estimation.
Test result: 3 are shown in Table.
3 heat resistant test result of table
Group Whether there is water-oil separating before test Whether there is water-oil separating after test
Test 1 group It is no It is no
Test 2 groups It is no It is
Conclusion (of pressure testing): heat resistant test shows after polyacrylic acid grafted starch is added in essence dew of the present invention that essence dew has Better stability.
Prepare embodiment
Embodiment 1
Essence reveals raw material are as follows: water 65g, hydroxyethyl cellulose 0.2g, polyacrylic acid grafted starch 0.10g, glycerol 2g, 1,3- Butanediol 5g, glycine betaine 0.4g, isoprene 1.5g, 1,2- hexylene glycol 0.4g, EDTA- disodium 0.04g, PEG-40 hydrogenated castor Oily 0.25g, olive oil PEG-7 esters 0.25g, tocopherol 0.08g, octyl dodecanol 0.08g, dried tremella extract 0.001g, horse Sativa extract 15g, trehalose 0.08g, Sodium Hyaluronate 0.004g, dipotassium glycyrrhizinate 0.04g, beta glucan 0.30g, silver 0.20g。
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Embodiment 2
Essence reveals raw material are as follows: water 70g, hydroxyethyl cellulose 0.4g, polyacrylic acid grafted starch 0.20g, glycerol 4g, 1,3- Butanediol 8g, glycine betaine 0.6g, isoprene 2.5g, 1,2- hexylene glycol 0.6g, EDTA- disodium 0.06g, PEG-40 hydrogenated castor Oily 0.35g, olive oil PEG-7 esters 0.35g, tocopherol 0.12g, octyl dodecanol 0.12g, dried tremella extract 0.001g, horse Sativa extract 20g, trehalose 0.12g, Sodium Hyaluronate 0.006g, dipotassium glycyrrhizinate 0.06g, beta glucan 0.30g, silver 0.20g。
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Embodiment 3
Essence reveal raw material are as follows: water 66g, hydroxyethyl cellulose 0.25g, polyacrylic acid grafted starch 0.12g, glycerol 2.5g, 1,3-BDO 5.5g, glycine betaine 0.45g, isoprene 1.6g, 1,2- hexylene glycol 0.45g, EDTA- disodium 0.05g, PEG-40 Rilanit special 0.28g, olive oil PEG-7 esters 0.28g, tocopherol 0.09g, octyl dodecanol 0.09g, dried tremella extract 0.001g, purslane extract 18g, trehalose 0.09g, Sodium Hyaluronate 0.005g, dipotassium glycyrrhizinate 0.045g, beta glucan 0.30g, silver 0.20g.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Embodiment 4
Essence reveals raw material are as follows: water 67g, hydroxyethyl cellulose 0.3g, polyacrylic acid grafted starch 0.15g, glycerol 3g, 1,3- Butanediol 6.5g, glycine betaine 0.5g, isoprene 2.0g, 1,2- hexylene glycol 0.5g, EDTA- disodium 0.05g, PEG-40 hydrogenate castor Sesame oil 0.30g, olive oil PEG-7 esters 0.30g, tocopherol 0.10g, octyl dodecanol 0.10g, dried tremella extract 0.001g, Purslane extract 17.5g, trehalose 0.10g, Sodium Hyaluronate 0.005g, dipotassium glycyrrhizinate 0.05g, beta glucan 0.30g, Silver-colored 0.20g.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Embodiment 5
Essence reveal raw material are as follows: water 68g, hydroxyethyl cellulose 0.35g, polyacrylic acid grafted starch 0.18g, glycerol 3.5g, 1,3-BDO 7g, glycine betaine 0.55g, isoprene 2.4g, 1,2- hexylene glycol 0.55g, EDTA- disodium 0.05g, PEG-40 hydrogen Change castor oil 0.32g, olive oil PEG-7 esters 0.32g, tocopherol 0.11g, octyl dodecanol 0.11g, dried tremella extract 0.001g, purslane extract 18g, trehalose 0.11g, Sodium Hyaluronate 0.005g, dipotassium glycyrrhizinate 0.05g, beta glucan 0.30g, silver 0.20g.
The essence dew the preparation method comprises the following steps:
Water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;PEG-40 hydrogenation is added Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
Stability test research
Test 1: different essence: being revealed the plastic drug package that 2 bottles of clean dries are added, tightens lid by heat resistant test, and one bottle Being put into and being pre-adjusted temperature is to take out after 48 hours in 48 ± 1 DEG C of insulating box, restore after room temperature with another bottle of progress mesh Survey is compared.
Test 2: different essence: being revealed the plastic drug package that 2 bottles of clean dries are added, tightens lid by low temperature resistant test, and one bottle Being put into and being pre-adjusted temperature is to take out after 48 hours in -18 ± 1 DEG C of refrigerator, restore after room temperature with another bottle of progress mesh Survey is compared.
Test 3: different essence: being revealed the plastic drug package that 2 bottles of clean dries are added, tightens lid by Light Resistance Test, and one bottle It places and is exposed to the sun 30 days under sunlight.
Test result: 4 are shown in Table.
4 stability test result of table
Aforementioned stable experiments have shown that, essence of the present invention dew has good stability.
It is including but not limited to above-mentioned to prepare embodiment.

Claims (3)

1. a kind of moisturizing is releived, essence is revealed, it is characterised in that: essence dew is prepared by following raw materials: water 65-70 parts by weight, Hydroxyethyl cellulose 0.2-0.4 parts by weight, polyacrylic acid grafted starch 0.10-0.20 parts by weight, glycerol 2-4 parts by weight, 1,3- Butanediol 5-8 parts by weight, glycine betaine 0.4-0.6 parts by weight, isoprene 1.5-2.5 parts by weight, 1,2- hexylene glycol 0.4-0.6 weight Measure part, EDTA- disodium 0.04-0.06 parts by weight, Cremophor RH40 0.25-0.35 parts by weight, olive oil PEG-7 esters 0.25-0.35 parts by weight, tocopherol 0.08-0.12 parts by weight, octyl dodecanol 0.08-0.12 parts by weight, dried tremella extract 0.001 parts by weight, purslane extract 15-20 parts by weight, trehalose 0.08-0.12 parts by weight, Sodium Hyaluronate 0.004- 0.006 parts by weight, dipotassium glycyrrhizinate 0.04-0.06 parts by weight, beta glucan 0.05-0.15 parts by weight, silver 0.1-0.3 weight Part.
2. a kind of moisturizing according to claim 1 is releived essence reveal, it is characterised in that: the essence dew the preparation method comprises the following steps:
It is water intaking, glycerol, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycol, hydroxyethyl cellulose, polyacrylic acid grafted Starch, EDETATE SODIUM, trehalose are added water phase pot, after being heated to 80-85 DEG C, stir evenly, and are pumped into agitated kettle;
Booting is uniformly mixed, and 30 minutes, 1000rpm, is stopped stirring, is cooled to 40 DEG C;Addition Cremophor RH40, Olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, glycyrrhizic acid two Potassium, beta glucan, silver continue to stir evenly, and are cooled to room temperature to get essence dew.
3. a kind of moisturizing according to claim 1 or 2 is releived, essence is revealed, it is characterised in that skin moisture-keeping, skin are releived Application in cosmetics.
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