CN107753333A - Elite dew that a kind of moisturizing is releived and preparation method thereof - Google Patents

Elite dew that a kind of moisturizing is releived and preparation method thereof Download PDF

Info

Publication number
CN107753333A
CN107753333A CN201711013365.8A CN201711013365A CN107753333A CN 107753333 A CN107753333 A CN 107753333A CN 201711013365 A CN201711013365 A CN 201711013365A CN 107753333 A CN107753333 A CN 107753333A
Authority
CN
China
Prior art keywords
weight
parts
elite
extract
glycine betaine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201711013365.8A
Other languages
Chinese (zh)
Other versions
CN107753333B (en
Inventor
何廷刚
朱思阳
艾勇
黄垂凡
张智婷
艾艳
夏菲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUA AN TANG BIOTECH GROUP Co.,Ltd.
Original Assignee
Guangzhou Heji Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Heji Biotechnology Co Ltd filed Critical Guangzhou Heji Biotechnology Co Ltd
Priority to CN201711013365.8A priority Critical patent/CN107753333B/en
Publication of CN107753333A publication Critical patent/CN107753333A/en
Application granted granted Critical
Publication of CN107753333B publication Critical patent/CN107753333B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to cosmetic technical field, and in particular to elite dew that a kind of moisturizing is releived and preparation method thereof, elite dew are prepared by following raw materials:Purslane extract, dried tremella extract and glycine betaine, purslane extract containing high content in the cosmetics, so as to ensure that cosmetics have the moisturizing effect of releiving, research shows, cosmetics of the present invention have good stability, have good moisture-keeping function for Skin Cell.

Description

Elite dew that a kind of moisturizing is releived and preparation method thereof
Technical field
The invention belongs to cosmetic technical field, and in particular to elite dew that a kind of moisturizing is releived and preparation method thereof.
Background technology
The skin of people divides epidermis, corium and subcutaneous fat.The outermost layer of epidermis is cuticula, due to cuticula in itself Contained NMF is the work of amino acids, lactate and carbohydrate etc. in water suction, barrier function, and cuticula With making cuticula keep certain water content, maintain the moistening of skin.And the outward appearance of skin and the moisture of cuticula have Close, normal keratoderma usually contains 10%-30% moisture, to maintain the soft and elastic of skin.But with the age Growth, keratoderma moisture can gradually decrease, and when the moisture of keratoderma is less than 10%, and skin is just Dry, tight, coarse and furfur etc. occurs.In general, the unbalanced internal and external condition of skin natural moisture preserving structure is caused Mainly have:1st, as the increasing at age, skin aging, its moisture-keeping function and barrier function gradually weaken, NMF content Reduce.2nd, cold weather is dried, humidity is relatively low, such as autumn and winter.3rd, some cutaneous lesions, such as psoriasis, ichthyosis 4, ring The organic solvent such as border and chemical factor, such as washing powder, soap, liquid detergent detergent and wine, and prolonged air conditioner surroundings Deng.5th, diet sleep habit, such as partial eclipse, drink water less, insomnia.Above-mentioned various reasons cause the skin of people to occur water shortage for a long time Symptom, and then cause more skin problems, such as long spot, small pox, wrinkle, relaxation, therefore be most basic to skin moisture-keeping Skin care step.
In summary, research and develop it is a kind of with moisturizing releive effect cosmetics it is significant.
The content of the invention
For these reasons, applicant has found a kind of new cosmetics, contained in the cosmetics containing height by studying for many years The purslane extract of amount, so as to ensure that cosmetics have the moisturizing effect of releiving after being combined with other compositions, research shows, this hair Bright cosmetics have good stability, have good moisture-keeping function for Skin Cell.
What the present invention was achieved through the following technical solutions.
A kind of moisturizing releive elite dew, the elite dew is prepared by following raw materials:Purslane extract, dried tremella extract And glycine betaine.
Elite dew is prepared by following raw materials:Purslane extract 15-20 parts by weight, the weight of dried tremella extract 0.001 Measure part, glycine betaine 0.4-0.6 parts by weight.
Elite dew is prepared by following raw materials:Purslane extract, dried tremella extract, glycine betaine, hydroxy ethyl fiber Plain, polyacrylic acid grafted starch, EDTA- disodiums, tocopherol, trehalose, Sodium Hyaluronate, dipotassium glycyrrhizinate, beta glucan, Silver.
Elite dew is prepared by following raw materials:Water, hydroxyethyl cellulose, polyacrylic acid grafted starch, glycerine, 1,3- Butanediol, glycine betaine, isoprene, 1,2- hexylene glycols, EDTA- disodiums, Cremophor RH40, olive oil PEG-7 esters, Tocopherol, octyl dodecanol, dried tremella extract, purslane extract, trehalose, Sodium Hyaluronate, dipotassium glycyrrhizinate, β-Portugal gather Sugar, silver.
Elite dew is prepared by following raw materials:Water 65-70 parts by weight, hydroxyethyl cellulose 0.2-0.4 parts by weight, gather Acrylic acid grafted starch 0.10-0.20 parts by weight, glycerine 2-4 parts by weight, 1,3-BDO 5-8 parts by weight, glycine betaine 0.4-0.6 Parts by weight, isoprene 1.5-2.5 parts by weight, 1,2- hexylene glycol 0.4-0.6 parts by weight, EDTA- disodium 0.04-0.06 weight Part, Cremophor RH40 0.25-0.35 parts by weight, olive oil PEG-7 esters 0.25-0.35 parts by weight, tocopherol 0.08- 0.12 parts by weight, octyl dodecanol 0.08-0.12 parts by weight, the parts by weight of dried tremella extract 0.001, purslane extract 15-20 Parts by weight, trehalose 0.08-0.12 parts by weight, Sodium Hyaluronate 0.004-0.006 parts by weight, dipotassium glycyrrhizinate 0.04-0.06 Parts by weight, beta glucan 0.05-0.15 parts by weight, silver-colored 0.1-0.3 parts by weight.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
A kind of described moisturizing releive elite dew, the application in the cosmetics releived in skin moisture-keeping, skin.
Raw material of the present invention is purchased from and is shown in Table 1:
1 raw material sources of the present invention of table
Raw material Purchased from producer Date of manufacture
Hydroxyethyl cellulose U.S. Ya Shilan 2016.04.03
Polyacrylic acid grafted starch Daito Kasei Kogyo 2015.12.06
Glycerine Cocoanut tree Acidchem 2016.08.09
1,3-BDO Japan DAICEL 2017.01.08
Glycine betaine Asahi Chemical Industry Asahi Kasel 2016.04.03
Isoprene Japan Kuraray 2016.05.10
1,2- hexylene glycol Symrise 2016.02.18
EDTA- disodiums Aksu AKZO NOBEL 2016.01.19
Cremophor RH40 German BASF 2016.11.23
Olive oil PEG-7 esters Taiwan CORUM 2015.12.24
Tocopherol Zhejiang YIYAO 2017.03.05
Purslane extract Guangzhou standing grain base 2016.09.08
Trehalose Japanese woods is former 2016.05.04
Sodium Hyaluronate The prosperous Fu Ruida of China 2017.02.23
Dipotassium glycyrrhizinate Gansu Qinghai Lake medicine company 2016.10.21
Beta glucan Korea Macrocare Tech 2015.11.29
Silver The Japan longevity chambers of commerce 2017.05.08
Specific embodiment
Technical scheme, but protection scope of the present invention not limited to this are illustrated with specific embodiment below.
Content described in this specification embodiment is only enumerating to the way of realization of inventive concept, protection of the invention Scope is not construed as being only limitted to the concrete form that embodiment is stated, protection scope of the present invention is also and in art technology Personnel according to present inventive concept it is conceivable that equivalent technologies mean.Although embodiment of the invention below is retouched State, but the invention is not limited in above-mentioned specific embodiments and applications field, following specific embodiments are only to show It is meaning property, guiding rather than restricted.One of ordinary skill in the art is under the enlightenment of this specification and is not taking off In the case of the scope protected from the claims in the present invention, the form of many kinds can also be made, these belong to the present invention The row of protection.
The following experiments of the present invention, it is on the basis of multiple creative experiment, with the claimed technical scheme of the present invention Based on, the conclusive experiment of the research staff of summary.
Experiment 1
Moisturizing experimental study
Test 1 group:Water 67mg, hydroxyethyl cellulose 0.3mg, polyacrylic acid grafted starch 0.15mg, glycerine 3mg, 1,3- Butanediol 6.5mg, glycine betaine 0.5mg, isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodiums 0.05mg, PEG-40 Rilanit special 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, white fungus extraction Thing 0.001mg, purslane extract 17.5mg, trehalose 0.10mg, Sodium Hyaluronate 0.005mg, dipotassium glycyrrhizinate 0.05mg, Beta glucan 0.30mg, silver-colored 0.20mg.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Test 2 groups:Water 67mg, hydroxyethyl cellulose 0.3mg, polyacrylic acid grafted starch 0.15mg, glycerine 3mg, 1,3- Butanediol 6.5mg, glycine betaine 0.5mg, isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodiums 0.05mg, PEG-40 Rilanit special 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, white fungus extraction Thing 0.001mg, purslane extract 0.005mg, trehalose 0.10mg, Sodium Hyaluronate 17.5mg, dipotassium glycyrrhizinate 0.05mg, Beta glucan 0.30mg, silver-colored 0.20mg.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Test method:Sodium Hyaluronate (cosmetics-stage);Ammonium sulfate and discoloration silica gel;MTT;Cell culture medium:Contain The MEM culture mediums of 10% calf serum (PAA), 100U/ml penicillin and 100U/ml streptomysins;0.25% pancreatin;Cell people's table Cornu cutaneum cell plastid strain HaCat;
When epidermal growth to fusion rate is up to more than 80%, adds the MEM culture mediums without calf serum and make synchronously Change processing 12h, collected by trypsinisation, cell concentration is adjusted after counting, be seeded to 24 well culture plates.After cell attachment, add μ g/ml of test group cosmetics 1000 prepared is diluted with culture medium in advance, is incubated, positive control is Sodium Hyaluronate (1000μg/ml).After 24h, it is placed in super-clean bench under certain wind speed after processing is dried, adds fresh culture, continue to train 24h is supported, carries out MTT measure.In experiment blank control group is used as using without any processing group.Cell is calculated as follows to dry The death rate (%) and protection ratio (%).
Cell dries the death rate (%)=(1- detection group OD values/normal group OD values) × 100%
Protection ratio (%)=(blank group cell dries the death rate-test group cell and dries the death rate)/blank group cell is done The dry death rate × 100%
Result of the test:It is shown in Table 1.
The each group epidermal cell of table 1 dries the comparison of the death rate and protection ratio
Note:The * * P compared with blank group<0.01, * P<0.05.
Conclusion (of pressure testing):It was found from to epidermal cell dry-run protection experimental study, positive controls show preferably thin Born of the same parents' protective effect, and test group of the present invention also has good cytoprotection, purslane extract is substituted for equal Sodium Hyaluronate (2 groups of experiment), declines to cytoprotection, further proves, elite dew of the present invention can significantly be resisted dry The dry damage to epidermal cell, the influence dried to cell viability is reduced, there is good moisture-keeping function.
Experiment 2
Heat resistant test
Test 1 group:Water 67mg, hydroxyethyl cellulose 0.3mg, polyacrylic acid grafted starch 0.15mg, glycerine 3mg, 1,3- Butanediol 6.5mg, glycine betaine 0.5mg, isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodiums 0.05mg, PEG-40 Rilanit special 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, white fungus extraction Thing 0.001mg, purslane extract 17.5mg, trehalose 0.10mg, Sodium Hyaluronate 0.005mg, dipotassium glycyrrhizinate 0.05mg, Beta glucan 0.30mg, silver-colored 0.20mg.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Test 2 groups:Water 67mg, hydroxyethyl cellulose 0.3mg, glycerine 3mg, 1,3-BDO 6.5mg, glycine betaine 0.5mg, Isoprene 2.0mg, 1,2- hexylene glycol 0.5mg, EDTA- disodiums 0.05mg, Cremophor RH40 0.30mg, olive oil PEG-7 esters 0.30mg, tocopherol 0.10mg, octyl dodecanol 0.10mg, dried tremella extract 0.001mg, purslane extract 17.5mg, trehalose 0.10mg, Sodium Hyaluronate 0.005mg, dipotassium glycyrrhizinate 0.05mg, beta glucan 0.30mg, silver 0.20mg。
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, EDTA bis- Sodium, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.Test method:By different elite Dew adds the plastic drug package of 2 bottles of clean dries, tightens lid, and one bottle is put into the constant temperature for being pre-adjusted that temperature is 48 ± 1 DEG C In case, taken out after 48 hours, range estimation comparison is carried out with another bottle after recovery room temperature.
Result of the test:It is shown in Table 3.
The heat resistant test result of table 3
Group Whether there is water-oil separating before experiment Whether there is water-oil separating after experiment
Test 1 group It is no It is no
Test 2 groups It is no It is
Conclusion (of pressure testing):Heat resistant test shows that after adding polyacrylic acid grafted starch in elite dew of the present invention, elite dew has More preferable stability.
Prepare embodiment
Embodiment 1
Elite reveals raw material:Water 65g, hydroxyethyl cellulose 0.2g, polyacrylic acid grafted starch 0.10g, glycerine 2g, 1,3- Butanediol 5g, glycine betaine 0.4g, isoprene 1.5g, 1,2- hexylene glycol 0.4g, EDTA- disodium 0.04g, PEG-40 hydrogenated castors Oily 0.25g, olive oil PEG-7 esters 0.25g, tocopherol 0.08g, octyl dodecanol 0.08g, dried tremella extract 0.001g, horse Sativa extract 15g, trehalose 0.08g, Sodium Hyaluronate 0.004g, dipotassium glycyrrhizinate 0.04g, beta glucan 0.30g, silver 0.20g。
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Embodiment 2
Elite reveals raw material:Water 70g, hydroxyethyl cellulose 0.4g, polyacrylic acid grafted starch 0.20g, glycerine 4g, 1,3- Butanediol 8g, glycine betaine 0.6g, isoprene 2.5g, 1,2- hexylene glycol 0.6g, EDTA- disodium 0.06g, PEG-40 hydrogenated castors Oily 0.35g, olive oil PEG-7 esters 0.35g, tocopherol 0.12g, octyl dodecanol 0.12g, dried tremella extract 0.001g, horse Sativa extract 20g, trehalose 0.12g, Sodium Hyaluronate 0.006g, dipotassium glycyrrhizinate 0.06g, beta glucan 0.30g, silver 0.20g。
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Embodiment 3
Elite reveals raw material:Water 66g, hydroxyethyl cellulose 0.25g, polyacrylic acid grafted starch 0.12g, glycerine 2.5g, 1,3-BDO 5.5g, glycine betaine 0.45g, isoprene 1.6g, 1,2- hexylene glycol 0.45g, EDTA- disodiums 0.05g, PEG-40 Rilanit special 0.28g, olive oil PEG-7 esters 0.28g, tocopherol 0.09g, octyl dodecanol 0.09g, dried tremella extract 0.001g, purslane extract 18g, trehalose 0.09g, Sodium Hyaluronate 0.005g, dipotassium glycyrrhizinate 0.045g, beta glucan 0.30g, silver-colored 0.20g.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Embodiment 4
Elite reveals raw material:Water 67g, hydroxyethyl cellulose 0.3g, polyacrylic acid grafted starch 0.15g, glycerine 3g, 1,3- Butanediol 6.5g, glycine betaine 0.5g, isoprene 2.0g, 1,2- hexylene glycol 0.5g, EDTA- disodiums 0.05g, PEG-40 hydrogenation castor Sesame oil 0.30g, olive oil PEG-7 esters 0.30g, tocopherol 0.10g, octyl dodecanol 0.10g, dried tremella extract 0.001g, Purslane extract 17.5g, trehalose 0.10g, Sodium Hyaluronate 0.005g, dipotassium glycyrrhizinate 0.05g, beta glucan 0.30g, Silver-colored 0.20g.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Embodiment 5
Elite reveals raw material:Water 68g, hydroxyethyl cellulose 0.35g, polyacrylic acid grafted starch 0.18g, glycerine 3.5g, 1,3-BDO 7g, glycine betaine 0.55g, isoprene 2.4g, 1,2- hexylene glycol 0.55g, EDTA- disodium 0.05g, PEG-40 hydrogen Change castor oil 0.32g, olive oil PEG-7 esters 0.32g, tocopherol 0.11g, octyl dodecanol 0.11g, dried tremella extract 0.001g, purslane extract 18g, trehalose 0.11g, Sodium Hyaluronate 0.005g, dipotassium glycyrrhizinate 0.05g, beta glucan 0.30g, silver-colored 0.20g.
The elite dew preparation method be:
Water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid Graft starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenations Castor oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, Dipotassium glycyrrhizinate, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
Stability test is studied
Experiment 1:Heat resistant test:Different elite are revealed to the plastic drug package for adding 2 bottles of clean dries, tighten lid, one bottle It is put into and has been pre-adjusted in the insulating box that temperature is 48 ± 1 DEG C, taken out after 48 hours, mesh is carried out with another bottle after recovery room temperature Survey is compared.
Experiment 2:Low temperature resistant test:Different elite are revealed to the plastic drug package for adding 2 bottles of clean dries, tighten lid, one bottle It is put into and has been pre-adjusted in the refrigerator that temperature is -18 ± 1 DEG C, taken out after 48 hours, mesh is carried out with another bottle after recovery room temperature Survey is compared.
Experiment 3:Light Resistance Test:Different elite are revealed to the plastic drug package for adding 2 bottles of clean dries, tighten lid, one bottle Place and be exposed to the sun 30 days under sunlight.
Result of the test:It is shown in Table 4.
The stability test result of table 4
Aforementioned stable experiment shows that elite dew of the present invention has good stability.
It is including but not limited to above-mentioned to prepare embodiment.

Claims (7)

1. a kind of moisturizing is releived, elite is revealed, it is characterised in that:Elite dew is prepared by following raw materials:Purslane extract, Dried tremella extract and glycine betaine.
2. a kind of moisturizing according to claim 1 is releived, elite is revealed, it is characterised in that:Elite dew is prepared by following raw materials Form:Purslane extract 15-20 parts by weight, the parts by weight of dried tremella extract 0.001, glycine betaine 0.4-0.6 parts by weight.
3. a kind of moisturizing according to claim 1 is releived, elite is revealed, it is characterised in that:Elite dew is prepared by following raw materials Form:Purslane extract, dried tremella extract, glycine betaine, hydroxyethyl cellulose, polyacrylic acid grafted starch, EDTA- disodiums, Tocopherol, trehalose, Sodium Hyaluronate, dipotassium glycyrrhizinate, beta glucan, silver.
4. a kind of moisturizing according to claim 1 is releived, elite is revealed, it is characterised in that:Elite dew is prepared by following raw materials Form:Water, hydroxyethyl cellulose, polyacrylic acid grafted starch, glycerine, 1,3-BDO, glycine betaine, isoprene, 1,2- oneself Glycol, EDTA- disodiums, Cremophor RH40, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, Purslane extract, trehalose, Sodium Hyaluronate, dipotassium glycyrrhizinate, beta glucan, silver.
5. a kind of moisturizing according to claim 1 is releived, elite is revealed, it is characterised in that:Elite dew is prepared by following raw materials Form:Water 65-70 parts by weight, hydroxyethyl cellulose 0.2-0.4 parts by weight, polyacrylic acid grafted starch 0.10-0.20 parts by weight, Glycerine 2-4 parts by weight, 1,3-BDO 5-8 parts by weight, glycine betaine 0.4-0.6 parts by weight, isoprene 1.5-2.5 parts by weight, 1,2- hexylene glycol 0.4-0.6 parts by weight, EDTA- disodium 0.04-0.06 parts by weight, Cremophor RH40 0.25-0.35 weights Measure part, olive oil PEG-7 esters 0.25-0.35 parts by weight, tocopherol 0.08-0.12 parts by weight, octyl dodecanol 0.08-0.12 Parts by weight, the parts by weight of dried tremella extract 0.001, purslane extract 15-20 parts by weight, trehalose 0.08-0.12 parts by weight, thoroughly Bright matter acid sodium 0.004-0.006 parts by weight, dipotassium glycyrrhizinate 0.04-0.06 parts by weight, beta glucan 0.05-0.15 parts by weight, Silver-colored 0.1-0.3 parts by weight.
A kind of 6. moisturizing elite dew according to claim 5, it is characterised in that:The elite dew preparation method be:
It is water intaking, glycerine, isoprene, 1,3-BDO, glycine betaine, 1,2- hexylene glycols, hydroxyethyl cellulose, polyacrylic acid grafted Starch, EDETATE SODIUM, trehalose, aqueous phase pot is added, after being heated to 80-85 DEG C, is stirred, be pumped into agitated kettle;
Start is uniformly mixed, 30 minutes, 1000rpm/ points, is stopped stirring, is cooled to 40 DEG C;Add PEG-40 hydrogenated castors Oil, olive oil PEG-7 esters, tocopherol, octyl dodecanol, dried tremella extract, purslane extract, Sodium Hyaluronate, radix glycyrrhizae Sour dipotassium, beta glucan, silver, continue to stir, be cooled to room temperature, produce elite dew.
7. a kind of moisturizing according to claim any one of 1-6 is releived, elite is revealed, it is characterised in that skin moisture-keeping, skin relax Application in slow cosmetics.
CN201711013365.8A 2017-10-26 2017-10-26 A kind of essence that moisturizing is releived dew and preparation method thereof Active CN107753333B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711013365.8A CN107753333B (en) 2017-10-26 2017-10-26 A kind of essence that moisturizing is releived dew and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711013365.8A CN107753333B (en) 2017-10-26 2017-10-26 A kind of essence that moisturizing is releived dew and preparation method thereof

Publications (2)

Publication Number Publication Date
CN107753333A true CN107753333A (en) 2018-03-06
CN107753333B CN107753333B (en) 2019-03-19

Family

ID=61270373

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711013365.8A Active CN107753333B (en) 2017-10-26 2017-10-26 A kind of essence that moisturizing is releived dew and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107753333B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019195308A (en) * 2018-05-11 2019-11-14 ユニテックフーズ株式会社 Syneresis depressor
CN114903824A (en) * 2021-07-21 2022-08-16 郑瑾芳 Soothing and moisturizing mask
CN115487113A (en) * 2022-09-26 2022-12-20 海南大学 Emulsion containing clove fruit extract and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105943491A (en) * 2016-06-29 2016-09-21 广州市巧美化妆品有限公司 Moistening and moisturizing essence and preparation method thereof
KR20170078947A (en) * 2015-12-29 2017-07-10 주식회사 썬테라 Cosmetic composition comprising complex of plant extracts

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170078947A (en) * 2015-12-29 2017-07-10 주식회사 썬테라 Cosmetic composition comprising complex of plant extracts
CN105943491A (en) * 2016-06-29 2016-09-21 广州市巧美化妆品有限公司 Moistening and moisturizing essence and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
宋丽雅等: "《化妆品植物功效添加剂的研究与开发》", 30 September 2011, 中国轻工业出版社 *
汪多仁: "《现代高分子材料生产及应用手册》", 31 May 2002, 中国石化出版社 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019195308A (en) * 2018-05-11 2019-11-14 ユニテックフーズ株式会社 Syneresis depressor
JP7132593B2 (en) 2018-05-11 2022-09-07 ユニテックフーズ株式会社 syneresis inhibitor
CN114903824A (en) * 2021-07-21 2022-08-16 郑瑾芳 Soothing and moisturizing mask
CN114903824B (en) * 2021-07-21 2023-12-29 广州梵之容化妆品有限公司 Mask for relieving and preserving moisture
CN115487113A (en) * 2022-09-26 2022-12-20 海南大学 Emulsion containing clove fruit extract and preparation method and application thereof
CN115487113B (en) * 2022-09-26 2024-01-16 海南大学 Emulsion containing clove fruit extract and preparation method and application thereof

Also Published As

Publication number Publication date
CN107753333B (en) 2019-03-19

Similar Documents

Publication Publication Date Title
CN105997828B (en) Smear water light Essence
CN104473828B (en) A kind of dragon fruit stem end moisture retention liquid and preparation method thereof
CN106511160A (en) Moisturizing cream and preparation method thereof
CN107753333B (en) A kind of essence that moisturizing is releived dew and preparation method thereof
CN108042388A (en) A kind of moisturizing and skin rejuvenating facial mask and preparation method thereof
CN105434283B (en) A kind of water profit nourishes late frost and preparation method thereof
CN106389175A (en) Nourishing and moisturizing lotion containing rose essential oil
CN107184484A (en) A kind of skin-moisturizing, skin water containing Lavender and camomile extract
CN102688163A (en) Anti-skin aging skin care compound essential oil
CN104887595A (en) Skin moisturizer
CN103720621B (en) A kind of Entermorpha decocting in water algae mud facial film and preparation method thereof
CN107582438A (en) A kind of skin moisturizing cosmetics composition and its preparation technology containing shea butter
CN105326696A (en) Natural plant antioxidant essence milk and preparation method thereof
CN103720619A (en) Sargassum horneri boiled alga clay mask and preparation method thereof
CN107007499A (en) A kind of emulsion with moisturizing anti-radiation effect
KR100962344B1 (en) Cosmetic composition for removing blackhead
CN109172433A (en) A kind of long-acting moisture-keeping composition and its application in cosmetics
CN104814916A (en) Moisturizing essence and preparing method thereof
CN103735455B (en) One main laver decocting in water algae mud facial film and preparation method thereof
CN102406579A (en) Herbal sun-screening lotion
CN107456423A (en) A kind of blueberry freckle-removing beauty cream and preparation method thereof
CN101693002B (en) Technology for producing extract solution from aloe
CN104288019B (en) A kind of moisturizing Aloe glue and preparation method thereof
CN103690422A (en) Hydrating plant toning lotion
CN103356468B (en) Exfoliated bletilla face mask and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CP01 Change in the name or title of a patent holder
CP01 Change in the name or title of a patent holder

Address after: 511434 No. 9 Liuwei Street, Hualong Town, Panyu District, Guangzhou, Guangdong Province 101, 201 and 301

Patentee after: Guangdong Heji Biotechnology Co., Ltd.

Address before: 511434 No. 9 Liuwei Street, Hualong Town, Panyu District, Guangzhou, Guangdong Province 101, 201 and 301

Patentee before: GUANGZHOU HEJI BIOTECHNOLOGY CO., LTD.

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20210407

Address after: 510000 No.13, Liuwei street, Hualong Town, Panyu District, Guangzhou City, Guangdong Province (factory building)

Patentee after: HUA AN TANG BIOTECH GROUP Co.,Ltd.

Address before: 511434 101, 201, 301, No. 9, Liuwei street, Hualong Town, Panyu District, Guangzhou City, Guangdong Province

Patentee before: Guangdong Heji Biotechnology Co.,Ltd.