CN107746420A - 16β烷基甾体类化合物的制备方法 - Google Patents
16β烷基甾体类化合物的制备方法 Download PDFInfo
- Publication number
- CN107746420A CN107746420A CN201710899132.6A CN201710899132A CN107746420A CN 107746420 A CN107746420 A CN 107746420A CN 201710899132 A CN201710899132 A CN 201710899132A CN 107746420 A CN107746420 A CN 107746420A
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- CN
- China
- Prior art keywords
- steroid
- alkyl
- preparation
- compound
- steroid compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- NNPWVPDIRNJLIN-UHFFFAOYSA-N CC1(C(CC2)C(CCC(C3(C)C=C4)=CC4=O)C3=CC1)C2=O Chemical compound CC1(C(CC2)C(CCC(C3(C)C=C4)=CC4=O)C3=CC1)C2=O NNPWVPDIRNJLIN-UHFFFAOYSA-N 0.000 description 1
- WEFXSWSNKPLMFM-HUJHUNOGSA-N C[C@@H](CC(C1CC2)C3(C)CC=C1C(C)(C=C1)C2=CC1=O)C3=O Chemical compound C[C@@H](CC(C1CC2)C3(C)CC=C1C(C)(C=C1)C2=CC1=O)C3=O WEFXSWSNKPLMFM-HUJHUNOGSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710899132.6A CN107746420B (zh) | 2017-09-28 | 2017-09-28 | 16β烷基甾体类化合物的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201710899132.6A CN107746420B (zh) | 2017-09-28 | 2017-09-28 | 16β烷基甾体类化合物的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN107746420A true CN107746420A (zh) | 2018-03-02 |
CN107746420B CN107746420B (zh) | 2020-08-14 |
Family
ID=61255173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201710899132.6A Active CN107746420B (zh) | 2017-09-28 | 2017-09-28 | 16β烷基甾体类化合物的制备方法 |
Country Status (1)
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CN (1) | CN107746420B (zh) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002042319A2 (en) * | 2000-11-27 | 2002-05-30 | Entremed, Inc. | 2-substituted estrogens as antiangiogenic agents |
WO2003073985A2 (en) * | 2002-03-01 | 2003-09-12 | Entremed, Inc. | New methods of using antiangiogenic agents |
CN103641878A (zh) * | 2013-11-22 | 2014-03-19 | 湖南新合新生物医药有限公司 | 倍他米松中间体或其类似物的制备方法 |
CN104387433A (zh) * | 2014-12-01 | 2015-03-04 | 江西赣亮医药原料有限公司 | 一种氯倍他索的制备方法及丙酸氯倍他索的制备方法 |
CN105693802A (zh) * | 2016-04-12 | 2016-06-22 | 湖南新合新生物医药有限公司 | 16β-甲基甾族化合物的制备方法 |
-
2017
- 2017-09-28 CN CN201710899132.6A patent/CN107746420B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002042319A2 (en) * | 2000-11-27 | 2002-05-30 | Entremed, Inc. | 2-substituted estrogens as antiangiogenic agents |
WO2003073985A2 (en) * | 2002-03-01 | 2003-09-12 | Entremed, Inc. | New methods of using antiangiogenic agents |
CN103641878A (zh) * | 2013-11-22 | 2014-03-19 | 湖南新合新生物医药有限公司 | 倍他米松中间体或其类似物的制备方法 |
CN104387433A (zh) * | 2014-12-01 | 2015-03-04 | 江西赣亮医药原料有限公司 | 一种氯倍他索的制备方法及丙酸氯倍他索的制备方法 |
CN105693802A (zh) * | 2016-04-12 | 2016-06-22 | 湖南新合新生物医药有限公司 | 16β-甲基甾族化合物的制备方法 |
Non-Patent Citations (1)
Title |
---|
ATUL GUPTA ET AL.: "Simple and Efficient Synthesis of Steroidal Hybrids of Estrogen and Vitamin D3", 《SYNTHETIC COMMUNICATIONS》 * |
Also Published As
Publication number | Publication date |
---|---|
CN107746420B (zh) | 2020-08-14 |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: sixteen b Preparation Method of Alkyl Steroid Compounds Effective date of registration: 20230613 Granted publication date: 20200814 Pledgee: Hunan Bank Co.,Ltd. Jinshi Branch Pledgor: HUNAN XINHEXIN BIOLOGICAL MEDICINE Co.,Ltd. Registration number: Y2023980043801 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20230905 Granted publication date: 20200814 Pledgee: Hunan Bank Co.,Ltd. Jinshi Branch Pledgor: HUNAN XINHEXIN BIOLOGICAL MEDICINE Co.,Ltd. Registration number: Y2023980043801 |