CN107693793A

CN107693793A - The packaging compositions of hydrophily lipid composite, it is prepared and concocting method and application

Info

Publication number: CN107693793A
Application number: CN201710841757.7A
Authority: CN
Inventors: 雷凡琦; 王保红
Original assignee: Fujian Austrian Investment Development Co Ltd
Current assignee: Jiangsu Hailaikang Biotechnology Co ltd
Priority date: 2016-09-20
Filing date: 2017-09-18
Publication date: 2018-02-16
Anticipated expiration: 2037-09-18
Also published as: WO2018054265A1; CN107693793B; CN107744024A

Abstract

The present invention is provided containing emulsifying agent and liquid aliphatic hydrophily lipid composite and its packaging compositions, allotment application method, hydrophily lipid composite has excellent hydrophily, it can quickly be leached in water and form homogeneous, stable emulsion, it is prepared by easy to operation and canteen, pass through the rolling that mixes, shakes, homogeneous emulsion can be formed in 1~5 second, be advantageous to quick, the convenient allotment of lipid composite and water fluid, the advantages of with allocating, using immediately immediately, it is also beneficial to oral absorption and the utilization of liposoluble constituent；Present invention also offers its application in terms of medicine, special medicine purposes formula food, health food or nutraceutical is prepared, and greatly facilitates the instant allotment of user, uses immediately.

Description

The packaging compositions of hydrophily lipid composite, it is prepared and concocting method and application

Technical field the present invention relates to a kind of healthy product composition, the specifically packaged combination of hydrophily lipid composite, And preparation method thereof, its allotment uses and applies.

Healthy product composition of the present invention, including medicine, special medicine purposes formula food, health food, nutrition Food, cosmetics etc., the composition specifically containing emulsifying agent, water-free liquid aliphatic class.

Background technology one side, it is well known that the lipid material including unrighted acid is complete with water It is incompatible, however healthy product in use, generally require with the lipid material that health-nutrition acts on it is water miscible Health-nutrition material uses simultaneously, and prior art is that lipid material and water fluid are prepared as into emulsion supply patient or special Crowd uses, but this previously prepared emulsion, in order to keep the stability of emulsion, extend commercially available storage life, addition There is the emulsifying agent of a large amount of even excess, while in order to keep the stability of unrighted acid, also added with substantial amounts of antioxidant, prevent Rotten agent, and alkali compounds is used, such as the pH value of sodium hydroxide regulation emulsion, these are unfavorable for the oral suction of aliphatic acid Receive, or even health risk can be brought；Furthermore unrighted acid and ester, as leukotrienes, linoleic acid, oleic acid, arachidonic acid, CLA, conjugated linoleic acid glyceride, DHA, EPA, nervonic acid etc. are in aqueous mixed liquor, it is easy to and aoxidize, degrade, Temperature especially more than 40 DEG C, meeting accelerated degradation, causes a large amount of losses of unrighted acid, and have a strong impact on composition Quality safety.

On the other hand, lipid material, especially unrighted acid are very greasy when directly drinking and are difficult to Receive；Therefore prior art is orally ingested by the way that unrighted acid is made into soft capsule, and this is unfavorable for being orally ingested very much Convenience, be also unfavorable for being orally ingested for larger dose, nor be beneficial to oral absorption.

Chinese patent publication No. CN104397702A, CN104490773A, CN104397706A disclose containing phosphatide, its The emulsion compositions of its liposoluble substance and water, it is emulsified by high-speed stirred, the process of homogeneous, make liposoluble substance with Water forms homogeneous emulsion, is advantageous to edible and absorbs.Unfortunately, on the one hand, unrighted acid it is fat-soluble Material is in aqueous mixed liquor, it is easy to aoxidizes, degrades, especially the temperature more than 40 DEG C, meeting accelerated degradation, causes insatiable hunger With a large amount of losses of aliphatic acid, and the quality safety of composition is had a strong impact on.

Generally, water-free lipid composite, it has good stability, but water-free lipid composite, and its oiliness is strong, Completely immiscible and swim on the water surface with water, stirring or rocking can not be such that lipid composite is well mixed with water, and this is for fat The allotment of based composition is using totally unfavorable, in medical product or healthy food etc. in use, its use range critical constraints, especially It is for needing lipid composite being well mixed with aqua, or needs lipid composite being deployed into nutraceutical/special Homogenate diet that can be oral in medical usage formula food, is very difficult；Also, also to meet that user is quick, easy Ground carries out the allotment with aqua, and deployed mixed liquor is in emulsion, and is not susceptible to macroscopic layering, is advantageous to eat With and use.

In actual applications, water-free liquid aliphatic, it is being configured to be easy to the product shape being orally ingested with water fluid , should especially in the practical applications such as nutraceutical, special medicine purposes formula food, medicine or Clinical practice is prepared during state Meet following four condition：

1st, there is hydrophily, can be mixed with water fluid and disperse to form emulsion, to improve the greasy mouth that it is difficult to receive Sense；

2nd, stir or rock in a reservoir with water fluid, homogeneous emulsion can be formed in a short period of time, such as 10 Homogeneous emulsion is formed in second, to ensure quick and convenience when preparing；

3rd, the emulsion formed with water fluid has preferable stability, is susceptible to significantly be layered, such as at least Visible layering did not occurred in 1 minute, so that user has the longer time drunk or be orally ingested；

4th, the emulsion formed through slight wobble, can still form homogeneous emulsion, in favor of making after standing is layered User drinks or is orally ingested by phased manner.

Clearly for water-free lipid composite, prior art can not meet this above-mentioned four conditions, typically will not Aqueous lipid composite makes the preparation of soft capsule to use, and this strongly limits the intake demand of consumer or patient, example Such as, the patient of EN support is needed for that can not be swallowed, this soft capsule preparation is that its tube feed can not be taken in , it also limit oral absorption and the utilization of liposoluble substance.

The content of the invention has excellent hydrophily it is an object of the invention to provide a kind of, and in water fluid quickly Leach and form the lipid composite and its concocting method of emulsion.This lipid composite has excellent hydrophily, both protects Demonstrate,proved lipid composite production, storage transport, shelf life product quality, again be beneficial to adjusted when in use with water fluid Match somebody with somebody, dissolve, can quickly and easily use.

The invention provides the hydrophily lipid composite containing liquid aliphatic and emulsifying agent, the lipid composite and water After the mixing of base fluid body, shaken by shaking, emulsion can be formed.Further, present invention also offers its packaging compositions, preparation side Method, its allotment are used and applied.

Liquid aliphatic of the present invention, it is defined as presenting the aliphatic acid or grease of liquid at normal temperatures and pressures, including it is full And/or undersaturated aliphatic acid, saturation or undersaturated grease, the triglycerides of saturated or undersaturated aliphatic acid, saturation or not The diglyceride of the aliphatic acid of saturation, such as including but not limited to oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, glycerine two Ester, middle long chain fatty acids, etc..

The present invention provides the hydrophily lipid composite containing emulsifying agent, liposoluble substance A and liposoluble substance B, described Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol fatty acid Ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, The content of sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier with Weight ratio meter is 0.1%~6%；The liposoluble substance A is selected from following one or more materials：Oleic acid, linoleic acid, leukotrienes, Medium chain triglyceride, diglyceride, middle long chain fatty acids, wherein liposoluble substance A content are more than 45% with weight ratio meter；Institute State liposoluble substance B and be selected from following one or more materials：Nervonic acid (NA), DHA (22 carbon six Olefin(e) acid), EPA (eicosapentaenoic acid), arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugation it is sub- Olein, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, polyenoid phosphorus Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0~30%, preferably described liposoluble substance B content with Weight ratio meter is 0.01%~30%；For the content of the liposoluble substance B using weight ratio meter as 0~30%, expression is free of fat-soluble thing Matter B contains 30% liposoluble substance B to highest；The leukotrienes includes alpha-linolenic acid or gamma-Linolenic acid, the middle long-chain fat Acid includes medium chain fatty acid or long chain fatty acids.

Liposoluble substance A and liposoluble substance B of the present invention are fatty acid or liposoluble substance, typically from plant Extracted in thing oil or animal oil, or from vegetable oil or animal oil（Such as fish oil, krill oil）Further closed again after middle extraction Into compound or grease, for example, lecithin extracts from soybean oil or yolk, phosphatidylserine be with lecithin and Serine is raw material, after phosphatide enzymatic conversion reaction, is made after purification；For another example phytosterol is included from soybean oil, dish The cupreol that is extracted in seed oil, corn oil, sunflower oil, Tall oil, campesterol, stigmasterol etc.；

On the other hand, liposoluble substance A or liposoluble substance B of the present invention, it will usually be present in the ratio of certain content In grease, liposoluble substance A or liposoluble substance B of the present invention can also be to contain the liposoluble substance A or fat-soluble The vegetable oil or animal oil of substance B, or the chemical combination for further synthesizing or fermenting again after being extracted from vegetable oil or animal oil Thing or grease are applied to the present invention.For example, Purple Perilla Seed Oil of the alpha-linolenic acid content more than 30%, linseed oil, peony seed oil, U.S. The donor of rattan fruit oil or eucommia ulmoides seed oil as alpha-linolenic acid, applied to the present invention；Gamma -linolenic acid content is more than 8% γ-flax Donor of the acid lipid as gamma-Linolenic acid, applied to the present invention；

For example, the soybean oil of oleic acid or linoleic acid content more than 40%, corn oil, peanut oil, sunflower oil, olive oil, milk thistle Seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran oil, chilli seed Oil, Fructus Zanthoxyli oil, canola, coconut oil, cottonseed oil, wheat-germ oil, eucommia ulmoides seed oil, tomato seed oil, silybum marianum seed oil, south Melon seeds oil, krill oil, Camellia oil, including tea seed oil, camellia seed oil or tea oil, amygdalus pedunculata pall oil, smooth bark Lai wood fruit oil, salt Ground common seepweed seeds oil, oil and fat of sacha inchi, rhus glabra oil, peony seed oil, samara oil, imperial rice bran oil, granada seed oil, brucea fruit oil, see the moon Careless oil, blackcurrant oil, shea butter, borage oil, Litsea cubeba oil, pine-seed oil, hemp-seed oil, nut oil, canola oil or ginger Oil is used as oleic acid or linoleic donor, applied to the present invention；

For example, contain the medium chain fatty acid more than 11%, the long chain fatty acids more than 10%, middle length in middle long chain fatty acids edible oil The donor of long chain fatty acids, medium chain fatty acid or long chain fatty acids during chain fatty acid edible oil can be used as, applied to the present invention；

For example, acer truncatum seed oil or shark oil donor as nervonic acid of the neural acid content 3%~8%, applied to the present invention；

For example, DHA algal oil donor as DHA of the DHA content 3%~6%, applied to the present invention, DHA content is 3%~15% Donor as DHA of fish oil or fish oil extract, applied to the present invention, confession of krill oil of the DHA content more than 3% as DHA Body, applied to the present invention；

For example, soybean lecithin of the total phospholipids content more than 35%, krill oil, soybean lecithin, yolk phospholipid, egg yolk lecithin are made For the donor of phosphatide, applied to the present invention.

Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn 20th, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent preferably emulsifies using weight ratio meter as 0.05%~8% The content of agent is using weight ratio meter as 0.1%~6%；The liposoluble substance A is selected from medium chain triglyceride and following one or more Material：Oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, diglyceride, middle long chain fatty acids, wherein medium chain triglyceride exist Content in hydrophily lipid composite is using weight ratio meter as 30%~99%, and preferably the content of medium chain triglyceride is with weight ratio meter For 40%~99%, preferably the content of medium chain triglyceride is using weight ratio meter as 45%~98%；The liposoluble substance B is selected from following One or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, Conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content are using weight ratio meter as 0~30%, preferred liposoluble substance B content Using weight ratio meter as 0.01%~30%；The middle long chain fatty acids include medium chain fatty acid or long chain fatty acids, the emulsifying agent Also include its various model, specification, the degree of polymerization, esterification degree, mono-/bis-ester, or its monomer component for including, the phosphatide include ovum Phosphatide, phosphatidyl-ethanolamine, phosphatidylinositols or phosphatidyl glycerol；

The content of the liposoluble substance B is using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight ratio Be calculated as 0.05%~25%, preferably liposoluble substance B content using weight ratio meter as 0.01%, 0.02%, 0.03%, 0.04%, 0.05%、0.06%、0.07%、0.08%、0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、 1%、1.1%、1.2%、1.3%、1.4%、1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、 2.5%、2.6%、2.7%、2.8%、2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、 4.1%、4.2%、4.3%、4.4%、4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、 5.6%、5.7%、5.8%、5.9%、6%、6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、 7.2%、7.3%、7.4%、7.5%、7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、8.5%、8.6%、 8.7%、8.8%、8.9%、9%、9.1%、9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、11%、12%、 13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%。

Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn 20th, the content of span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%；The liposoluble Property substance A is selected from leukotrienes and following one or more materials：Oleic acid, linoleic acid, medium chain triglyceride, diglyceride, middle length The content of chain fatty acid, wherein leukotrienes in hydrophily lipid composite is using weight ratio meter as 30%~99%；It is described fat-soluble Substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, Rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content are described using weight ratio meter as 0.01%~30% Leukotrienes includes alpha-linolenic acid or gamma-Linolenic acid.

Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn 20th, the content of span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%；The liposoluble Property substance A is selected from linoleic acid and following one or more materials：It is oleic acid, alpha-linolenic acid, gamma-Linolenic acid, medium chain triglyceride, sweet Oily diester, middle long chain fatty acids, content of its Linoleic acid in hydrophily lipid composite is using weight ratio meter as 30%~99%； The liposoluble substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, dimension life Plain A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant Stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0.01%~ 30%。

Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn 20th, the content of span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%；The liposoluble Property substance A is selected from oleic acid and following one or more materials：It is linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, medium chain triglyceride, sweet Oily diester, middle long chain fatty acids, wherein content of the oleic acid in hydrophily lipid composite is using weight ratio meter as 30%~99%；Institute State liposoluble substance B and be selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant steroid Alkanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0.01%~ 30%。

Further specifically, present invention offer is a kind of to contain the hydrophilic of emulsifying agent, medium chain triglyceride and liposoluble substance A Property lipid composite, the liposoluble substance A selected from oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, middle long chain fatty acids, One or more in diglyceride, wherein medium chain triglyceride and liposoluble substance A content are more than 45% with weight ratio meter, The content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, most preferably The content of emulsifying agent is using weight ratio meter as 0.3%~2.5%.

Further specifically, present invention offer is a kind of to contain the hydrophilic of emulsifying agent, medium chain triglyceride and liposoluble substance B Property lipid composite, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension Raw plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol One or more in ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein the content of medium chain triglyceride is with weight ratio meter For 60%~99.5%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight Than being calculated as 0.05%~25%, preferably liposoluble substance B content using weight ratio meter as 0.01%, 0.02%, 0.03%, 0.04%, 0.05%、0.06%、0.07%、0.08%、0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、 1%、1.1%、1.2%、1.3%、1.4%、1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、 2.5%、2.6%、2.7%、2.8%、2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、 4.1%、4.2%、4.3%、4.4%、4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、 5.6%、5.7%、5.8%、5.9%、6%、6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、 7.2%、7.3%、7.4%、7.5%、7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、8.5%、8.6%、 8.7%、8.8%、8.9%、9%、9.1%、9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、11%、12%、 13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%。

Specifically, the present invention provide it is a kind of containing emulsifying agent, nervonic acid, liposoluble substance A hydrophily lipid composite, The liposoluble substance A is in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride One or more, liposoluble substance A content are more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~ 8%, for the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of nervonic acid is excellent using weight ratio meter as 0.01%~30% Select the content of nervonic acid using weight ratio meter as 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、1%、1.1%、1.2%、1.3%、1.4%、 1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、2.5%、2.6%、2.7%、2.8%、 2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、4.1%、4.2%、4.3%、4.4%、 4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、5.6%、5.7%、5.8%、5.9%、6%、 6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、7.2%、7.3%、7.4%、7.5%、 7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、8.5%、8.6%、8.7%、8.8%、8.9%、9%、9.1%、 9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、11%、12%、13%、14%、15%、16%、17%、18%、 19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%。

Specifically, the present invention provide it is a kind of containing emulsifying agent, DHA, liposoluble substance A hydrophily lipid composite, institute State one of liposoluble substance A in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride Kind or it is a variety of, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~ 8%, the content of preferred emulsifier is 0.1%~6%, DHA content using weight ratio meter as 0.01%~30% using weight ratio meter, preferably DHA content is using weight ratio meter as 0.04%~25%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, EPA, liposoluble substance A hydrophily lipid composite, institute State one of liposoluble substance A in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride Kind or it is a variety of, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~ 8%, the content of preferred emulsifier is 0.1%~6%, EPA content using weight ratio meter as 0.01%~30% using weight ratio meter, preferably EPA content is using weight ratio meter as 0.04%~25%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, arachidonic acid, liposoluble substance A hydrophily lipid group Compound, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride In one or more, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, arachidonic content using weight ratio meter as 0.01%~30%, preferably arachidonic content is using weight ratio meter as 0.04%~25%.

Specifically, the present invention provides a kind of hydrophily lipid combination containing emulsifying agent, vitamin E, liposoluble substance A Thing, the liposoluble substance A is in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride One or more, liposoluble substance A content is more than 45% with weight ratio meter, and the content of emulsifying agent is using weight ratio meter as 0.05% ~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of vitamin E using weight ratio meter as 0.01%~ 30%, preferred vitamin E content are using weight ratio meter as 0.04%~25%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, CLA, liposoluble substance A hydrophily lipid group Compound, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride In one or more, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of CLA using weight ratio meter as 0.01%~25%, preferably the content of CLA is using weight ratio meter as 0.04%~20%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, conjugated linoleic acid glyceride, liposoluble substance A hydrophily Lipid composite, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, sweet One or more in oily diester, liposoluble substance A content are more than 45% with weight ratio meter, and the content of emulsifying agent is with weight ratio 0.05%~8% is calculated as, the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, and the content of conjugated linoleic acid glyceride is with weight Amount ratio is calculated as 0.01%~25%, and preferably the content of conjugated linoleic acid glyceride is using weight ratio meter as 0.04%~20%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, phosphatidylserine, liposoluble substance A hydrophily lipid Composition, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, glycerine two One or more in ester, liposoluble substance A content are more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of phosphatidylserine using weight ratio meter as 0.01%~30%, preferably the content of phosphatidylserine is using weight ratio meter as 0.04%~25%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, Polyene Phosphatidylcholine, liposoluble substance A hydrophily fat Based composition, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, glycerine One or more in diester, liposoluble substance A content are more than 45% with weight ratio meter, and the content of emulsifying agent is with weight ratio meter For 0.05%~8%, the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, and the content of Polyene Phosphatidylcholine is with weight ratio 0.01%~25% is calculated as, preferably the content of Polyene Phosphatidylcholine is using weight ratio meter as 0.04%~25%.

Specifically, the present invention provides a kind of hydrophily lipid combination containing emulsifying agent, phytosterol, liposoluble substance A Thing, the liposoluble substance A is in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride One or more, liposoluble substance A content is more than 45% with weight ratio meter, and the content of emulsifying agent is using weight ratio meter as 0.05% ~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of phytosterol using weight ratio meter as 0.01%~ 30%, the content of preferred plant sterol is using weight ratio meter as 0.04%~25%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, phytosterin ester, liposoluble substance A hydrophily lipid group Compound, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride In one or more, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of phytosterin ester using weight ratio meter as 0.01%~30%, the content of preferred plant sterol ester is using weight ratio meter as 0.05%~26%.

Specifically, the present invention provide it is a kind of containing emulsifying agent, plant stanol ester, liposoluble substance A hydrophily lipid Composition, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, glycerine two One or more in ester, liposoluble substance A content are more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of plant stanol ester using weight ratio meter as 0.01%~30%, the content of preferred plant stanol ester is using weight ratio meter as 0.04%~25%.

Particularly, the present invention provides a kind of hydrophily lipid composite, containing leukotrienes, emulsifying agent, liposoluble substance B, The liposoluble substance B is selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane One or more in alcohol, Polyene Phosphatidylcholine, the leukotrienes include alpha-linolenic acid or gamma-Linolenic acid, wherein leukotrienes Content using weight ratio meter as 45%~99.5%, using weight ratio meter as 0.05%~8%, preferred emulsifier contains the content of emulsifying agent Amount is using weight ratio meter as 0.3%~2.5%, and liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferably fat-soluble thing Matter B content using weight ratio meter as 0.05%~20%, preferably liposoluble substance B content using weight ratio meter as 0.01%, 0.02%, 0.03%、0.04%、0.05%、0.06%、0.07%、0.08%、0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、 0.8%、0.9%、1%、1.1%、1.2%、1.3%、1.4%、1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、 2.3%、2.4%、2.5%、2.6%、2.7%、2.8%、2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、 3.8%、3.9%、4%、4.1%、4.2%、4.3%、4.4%、4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、 5.4%、5.5%、5.6%、5.7%、5.8%、5.9%、6%、6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、 6.9%、7%、7.1%、7.2%、7.3%、7.4%、7.5%、7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、 8.5%、8.6%、8.7%、8.8%、8.9%、9%、9.1%、9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、 11%、12%、13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、 30%。

The present invention provides a kind of hydrophily lipid composite, contains linoleic acid, emulsifying agent, liposoluble substance B, the liposoluble Property substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugation Glyceryl linoleate, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, polyenoid One or more in phosphatidyl choline, wherein linoleic content is using weight ratio meter as 45%~99%, the content of emulsifying agent with Weight ratio meter is 0.05%~8%, and the content of preferred emulsifier is using weight ratio meter as 0.3%~2.5%, liposoluble substance B content Using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content is preferably fat-soluble using weight ratio meter as 0.04%~25% The content of substance B is using weight ratio meter as 0.06%~23%.

The present invention provides a kind of hydrophily lipid composite, described fat-soluble containing oleic acid, emulsifying agent, liposoluble substance B It is sub- that substance B is selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugation Olein, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, polyenoid phosphorus The content of one or more in phosphatidylcholine, wherein oleic acid is using weight ratio meter as 45%~99%, and the content of emulsifying agent is with weight Than being calculated as 0.05%~8%, the content of preferred emulsifier is using weight ratio meter as 0.3%~2.5%, and liposoluble substance B content is with weight Amount ratio is calculated as 0.01%~30%, and preferably liposoluble substance B content is using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains medium chain triglyceride, emulsifying agent, liposoluble substance B, institute State liposoluble substance B and be selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane The content of one or more in alcohol, Polyene Phosphatidylcholine, wherein medium chain triglyceride using weight ratio meter as 40%~99.5%, For the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier is fat-soluble using weight ratio meter as 0.1%~6% The content of substance B using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~ 25%。

The present invention provides a kind of hydrophily lipid composite, contains diglyceride, emulsifying agent, liposoluble substance B, the fat Soluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, altogether It is conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, more Using weight ratio meter as 45%~99%, emulsifying agent contains the content of one or more in alkene phosphatidyl choline, wherein diglyceride Amount using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.3%~2.5%, liposoluble substance B's Content is using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains middle long chain fatty acids, emulsifying agent, liposoluble substance B, institute State liposoluble substance B and be selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane One or more in alcohol, Polyene Phosphatidylcholine, wherein the content of middle long chain fatty acids is using weight ratio meter as 45%~99%, it is newborn For the content of agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier is fat-soluble using weight ratio meter as 0.3%~2.5% The content of substance B using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~ 20%。

The present invention provides a kind of hydrophily lipid composite, contains oleic acid, linoleic acid, emulsifying agent, liposoluble substance B, institute State liposoluble substance B and be selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane One or more in alcohol, Polyene Phosphatidylcholine, wherein oleic acid and linoleic total content using weight ratio meter as 45%~99%, For the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier is fat-soluble using weight ratio meter as 0.1%~6% The content of substance B using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~ 20%。

The present invention provides a kind of hydrophily lipid composite, containing leukotrienes, linoleic acid, emulsifying agent, liposoluble substance B, The liposoluble substance B is selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane The total content of one or more in alcohol, Polyene Phosphatidylcholine, wherein linolenic and linoleic using weight ratio meter as 45%~ 99%, the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, fat Soluble substance B content is using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is using weight ratio meter as 0.05% ~20%.

The present invention provides a kind of hydrophily lipid composite, contains leukotrienes, medium chain triglyceride, emulsifying agent, fat-soluble Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran The total content of one or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein leukotrienes and medium chain triglyceride is with weight Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight Than being calculated as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains linoleic acid, medium chain triglyceride, emulsifying agent, fat-soluble Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran The total content of one or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, its Linoleic acid and medium chain triglyceride is with weight Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight Than being calculated as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, containing medium chain triglyceride, linoleic acid, leukotrienes, emulsifying agent, Liposoluble substance B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension life Plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol One or more in ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein medium chain triglyceride, linoleic acid plus linolenic acid Total content using weight ratio meter as 45%~99%, using weight ratio meter as 0.05%~8%, preferred emulsifier contains the content of emulsifying agent Amount is using weight ratio meter as 0.1%~6%, and liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferred liposoluble substance B content is using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains medium chain triglyceride, leukotrienes, linoleic acid, oleic acid, breast Agent, liposoluble substance B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant steroid One or more in alkanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein medium chain triglyceride, leukotrienes, sub- oil For the total content of acid and oleic acid using weight ratio meter as 45%~99%, the content of emulsifying agent is preferably newborn using weight ratio meter as 0.05%~8% The content of agent is using weight ratio meter as 0.1%~6%, and liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferred fat Soluble substance B content is using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, containing medium chain triglyceride, middle long chain fatty acids, emulsifying agent, Liposoluble substance B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension life Plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol One or more in ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein medium chain triglyceride and middle long chain fatty acids Total content is using weight ratio meter as 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, the content of preferred emulsifier Using weight ratio meter as 0.1%~6%, liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferably liposoluble substance B Content using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains medium chain triglyceride, diglyceride, emulsifying agent, liposoluble Property substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice The total content of one or more in chaff fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein medium chain triglyceride and diglyceride with Weight ratio meter is 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio 0.1%~6% is calculated as, liposoluble substance B content is using weight ratio meter as 0.01%~30%.

The present invention provides a kind of hydrophily lipid composite, contains leukotrienes, diglyceride, emulsifying agent, liposoluble substance It is sub- that B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Oleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats The total content of one or more in alkanol, Polyene Phosphatidylcholine, wherein leukotrienes and diglyceride is using weight ratio meter as 45% ~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, Liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains diglyceride, linoleic acid, emulsifying agent, liposoluble substance It is sub- that B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation Oleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats One or more in alkanol, Polyene Phosphatidylcholine, wherein diglyceride and linoleic total content are using weight ratio meter as 45% ~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, Liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains diglyceride, linoleic acid, leukotrienes, emulsifying agent, liposoluble Property substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice One or more in chaff fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein diglyceride, linoleic acid plus linolenic acid total content with Weight ratio meter is 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio Be calculated as 0.1%~6%, liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content with Weight ratio meter is 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains middle long chain fatty acids, diglyceride, emulsifying agent, liposoluble Property substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice One or more in chaff fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein the total content of middle long chain fatty acids and diglyceride with Weight ratio meter is 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio Be calculated as 0.1%~6%, liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content with Weight ratio meter is 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains leukotrienes, middle long chain fatty acids, emulsifying agent, fat-soluble Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran One or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein leukotrienes and the total content of middle long chain fatty acids are with weight Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight Than being calculated as 0.05%~20%.

The present invention provides a kind of hydrophily lipid composite, contains linoleic acid, middle long chain fatty acids, emulsifying agent, fat-soluble Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran The total content of one or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, its Linoleic acid and middle long chain fatty acids is with weight Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight Than being calculated as 0.05%~20%.

Emulsifying agent of the present invention is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerol fat Fat acid esters, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, tell Temperature 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.05%~ 8%, the content of preferred emulsifier is using weight ratio meter as 0.1%~6%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.07%~7%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.1%~6%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.2%~5%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.3%~4%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.4%~3.5%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.5%~3%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.6%~2.5%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.75%~2%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.8%~1.8%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.85%~1.7%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.9%~1.6%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.95%~1.5%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 1.0%~1.4%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.4%~1.6%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.5%~1.5%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.6%~1.4%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.7%~1.3%；

Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.8%~1.2%.

Wherein, the emulsifying agent also includes its various model, specification, the degree of polymerization, esterification degree, mono-/bis-ester, or it is included Monomer component.Specifically, phosphatide includes but is not limited to lecithin, phosphatidyl-ethanolamine, phosphatidylinositols or phosphatidyl glycerol, it is excellent Choosing, the lecithin in the phosphatide（That is phosphatidyl choline）Content be more than 40%, the lecithin in preferably described phosphatide contains Amount is more than 50%；It is preferred that the content of the lecithin in the phosphatide is more than 60%；Sucrose fatty ester includes but is not limited to its S-1 extremely S-16 various models；Single, diglycerine fatty acid ester includes but is not limited to single, bi-tristearin, list, double oleics Ester, list, dilaurate glyceride, list, dilinoleic acid glyceride, list, double glyceryl linolenates, list, double tripalmitins, It is single, double Compritol 888 ATOs；Polyglyceryl fatty acid ester includes but is not limited to polyglycerol stearate, Unigly GO 102S, poly- sweet Oily laurate, the dimer of polyglyceryl myristate or POGE-A, trimer, tetramer, hexamer, nine gather Thing, etc., such as including but not limited to three polyglycerol stearates, three Unigly GO 102Ss, three polyglyceryl laurates, trimerization Glycerine myristate ester, three POGE-As, four polyglycerol stearates, four Unigly GO 102Ss, four polyglycereol bays Acid esters, four polyglyceryl myristates, four POGE-As, two polyglycerol stearates, two Unigly GO 102Ss, dimerization Glycerol monolaurate, two polyglyceryl myristates, two POGE-As, six polyglycerol stearates, nine polyglycereol are hard Resin acid ester, etc.；It is stearic that methyl glycol fatty acid ester includes but is not limited to propylene glycol oleate, propane diols linoleate, propane diols Acid esters, etc.；Lactic acid fatty glyceride includes but is not limited to oleic acid, linoleic acid, stearic acid, linolenic glyceride lactate, Etc..

Preferably, the emulsifying agent is phosphatide, and the wherein content of phosphatide is using weight ratio meter as 0.2%~3.5%, preferred phosphatide Content using weight ratio meter as 0.5%~2.5%.

Preferably, the emulsifying agent is selected from phosphatide and following one or more materials：Sucrose fatty ester, list, diglycerol Fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.1%~ 4%, the content of preferred emulsifier is using weight ratio meter as 0.2%~3%.

Preferably, the emulsifying agent includes sucrose fatty ester and following one or more materials：Phosphatide, list, diglycerol Fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~ 5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.

Preferably, the emulsifying agent includes single, diglycerine fatty acid ester and following one or more materials：Phosphatide, sucrose Fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~ 5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.

Preferably, the emulsifying agent includes polyglyceryl fatty acid ester and following one or more materials：Phosphatide, sucrose fat Acid esters, list, diglycerine fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~ 5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.

Preferably, the emulsifying agent includes methyl glycol fatty acid ester and following one or more materials：Phosphatide, sucrose fat Acid esters, polyglyceryl fatty acid ester, list, diglycerine fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~ 5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.

Preferably, the emulsifying agent includes lactic acid fatty glyceride and following one or more materials：Phosphatide, Sucrose Fatty Acid Ester Fat acid esters, polyglyceryl fatty acid ester, list, diglycerine fatty acid ester, methyl glycol fatty acid ester, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~ 5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.

Specifically, it is preferred that the content of emulsifying agent of the present invention using weight ratio meter as 0.05%, 0.06%, 0.07%, 0.08%, 0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、1%、1.1%、1.2%、1.3%、1.4%、 1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、2.5%、2.6%、2.7%、2.8%、 2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、4.1%、4.2%、4.3%、4.4%、 4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、5.6%、5.7%、5.8%、5.9%、6%、 6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、7.2%、7.3%、7.4%、7.5%、 7.6%th, 7.7%, 7.8%, 7.9% or 8%.

Preferably, the lecithin in phosphatide of the present invention, preferably phosphatide（That is phosphatidyl choline）Content be more than 40%, It is preferred that the content of the lecithin in the phosphatide is more than 50%；It is preferred that the content of the lecithin in the phosphatide is more than 60%.

Specifically, it is preferred that the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill Oil.

Further, in the hydrophilic lipid composite of the present invention, other one or more functional components can also be contained, Such as include but is not limited to lutein, lutein ester, Co-Q10, carrotene, astaxanthin, lycopene, isoflavones, plant Thing extract or propolis.For example, special, esterified content astaxanthin is more than 500mg/kg krill oil, can be as astaxanthin Donor grease is applied in the hydrophilic lipid composite of the present invention.

Further, in the hydrophilic lipid composite of the present invention, can also containing taste improve composition, such as Including but not limited to flavorant or flavoring essence, sweetener, such as steviol glycoside, glycyrrhizin, Sucralose, etc..

Hydrophily lipid composite of the present invention, there is outstanding hydrophily, it shakes in water fluid through shaking, Homogeneous, stable emulsion can quickly be formed；

Or hydrophily lipid composite of the present invention, there is outstanding hydrophily, it is in the water fluid containing ethanol In, shaken through shaking, can quickly form homogeneous, stable emulsion.

Water fluid of the present invention, including water, water content are more than 60% liquid, or the aqueous solution containing ethanol.

Rolling of the present invention of shaking, refers to the operating method by vibrating, rocking or rock, mixture is produced in a reservoir Quick flowing, rolling or/and the motion of collision impact, mixture is set to produce rolling of shaking with hand including the use of person, or, using machine Operation makes mixture produce rolling of shaking, for example with the operation of manipulator.

Liquid aliphatic of the present invention, including the aliphatic acid or grease of liquid are presented at normal temperatures and pressures, preferably include Saturated or undersaturated aliphatic acid, saturation or undersaturated grease, the triglycerides of saturated or undersaturated aliphatic acid, saturation or The diglyceride of undersaturated aliphatic acid, such as including but not limited to oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, middle chain Triglycerides, diglyceride, middle long chain fatty acids, etc..

Emulsion is a complicated, thermodynamic stable system, especially different types of fats or fat-soluble ingredient, by Different in the fat-water distribution and combination energy state of each component, the stability for whole system is vital, multi-component fat Newborn system, it is easy to the wild effects such as fat floating, flocculation or layering, production method and technique occur, decide emulsion The form and size of middle fat globule, and the microphenomenons such as aggregation whether can occur, so as to influence the fat of emulsion in macroscopic aspect Fat floating, flocculation or layering etc. are unstable, in addition, also contributing to emulsion digesting and assimilating and utilizing to human body.

However, disadvantageously, after emulsifying agent mixes with vegetable oil, in the environment of normal temperature or slightly below normal temperature, it is long placed in meeting Become cloudy grease, such as phosphatide can separate out precipitation, have a strong impact on the quality of product.Inventor occurs such a existing by research As the reason for be due to emulsifying agent be not easy to vegetable oil be blended, such as phosphatide freezing point be higher than vegetable oil freezing point, make The phosphatide that can not be blended with vegetable oil is obtained, precipitation can be separated out at a temperature of less than its freezing point, so as to cause grease to become cloudy, Or phosphatide can separate out precipitation.

Therefore, the preparation method of hydrophily lipid composite of the present invention is vital that inventor has found, by adding Heat, mixed at high speed make emulsifying agent and vegetable oil generation blending, state of dissolving each other, and are allowed to be evenly distributed, and further quickly, precisely drop Temperature, or form the miscible composition of oil-gas, makes emulsifier molecules in rapid cooling, in emulsified dose point of high dispersion state Son can form the colloidal solution of small molecule crystallite state, reach the stable mixture of emulsifying agent and vegetable oil.

Further, the present invention provides a kind of preparation method of above-mentioned hydrophily lipid composite, and it includes：

(1) dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed Splitting or integrating dissipates uniform；

(2) liquid prepared in (1) is placed in emulsion tank, heating makes fluid temperature be more than 45 DEG C, big in speed of agitator Under conditions of 500r/min, speed of agitator is preferable over more than under conditions of 1000r/min, is stirred 3~25min of operation, Then rapidly by liquid cooling to less than 25 DEG C in 3~5min, stop stirring, stand；Or the liquid that will be prepared in (1) Body is placed in emulsion tank, and heating makes fluid temperature be more than 45 DEG C, and the homogeneous that pressure is 20~58MPa is carried out in homogenizer, Then rapidly by liquid cooling to less than 25 DEG C in 3~5min, stirring is stopped；

(3) it is filling：Oily liquids is subjected to vacuum outgas, it is filling, sealing, packaging, examine, produce hydrophily lipid group of the present invention Compound.

Hydrophily lipid composite prepared by the above method of the present invention, generally in the faint yellow clear oil to buff Thing.Further, hydrophily lipid composite and water fluid are shaken to be deployed into emulsion by shaking.

For hydrophily lipid composite of the present invention, compatibility and dispersiveness with water fluid are most important , the preparation method of composition miscible using oil-gas of the invention, produced altogether in liquid aliphatic for emulsifying agent It is mixed, and all there is good raising to act on for the hydrophily of lipid composite.Further, the invention provides hydrophily Second of preparation method of lipid composite, it includes：

(2) liquid prepared in (1) is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps emulsion tank In pressure be more than 1.3 atmospheric pressure, and be stirred 3~25min of operation under conditions of speed of agitator is more than 300r/min, make The oily liquids of the foam type rich in nitrogen of nontransparent shape is presented in oily liquids, stops stirring；

(3) it is filling：Will（2）The oily liquids of middle preparation is filling in container, optionally container is carried out to be filled with nitrogen, and make appearance Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces hydrophily lipid composite.

Hydrophily lipid composite prepared by the above method of the present invention, is the foam type grease thing containing nitrogen, is presented non- Transparence, estimate the visible wherein bubble containing fine uniform, or foam-like is presented in the grease of liquid.Further, will Hydrophily lipid composite is shaken to be deployed into emulsion with water fluid by shaking.

Further, the present invention provides the preparation method of the hydrophily lipid composite described in the third, and it includes：

（1）Dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, it is stand-by；

（2）Liquid aliphatic and liposoluble substance are mixed, stirring, its mixing is uniformly dispersed, obtain the mixing of liposoluble substance Thing；

（3）The premixing of emulsifying agent：Take 3~7 times of emulsifying agent and emulsifying agent weight（2）The mixing of the liposoluble substance of middle preparation Thing, it is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure, And stirred under conditions of speed of agitator is more than 300r/min, make oily liquids that the foam type rich in nitrogen of nontransparent shape be presented Oily liquids, or grease present foam-like, stop stirring；

（4）The pre-mixed material of the emulsifying agent prepared in (3) is placed in emulsion tank, adds the mixed of remaining liposoluble substance Compound, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure, and in speed of agitator More than being stirred under conditions of 300r/min, make oily liquids that the foam type grease thing rich in nitrogen of nontransparent shape be presented, stop Stirring；

(5) it is filling：Will（4）The oily liquids of middle preparation is filling in container, optionally container is carried out being filled with nitrogen and makes appearance Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces hydrophily lipid composite.Further, will Hydrophily lipid composite is shaken to be deployed into emulsion with water fluid by shaking.

Another aspect, the present invention provides one kind and contains emulsifying agent and liquid aliphatic hydrophily lipid composite, and it is special Sign is to be made of the first above-mentioned preparation method, second of preparation method or the third preparation method.

Further, the present invention provides a kind of hydrophily lipid composite of foam type, contains emulsification of the present invention Agent, liposoluble substance A, liposoluble substance B and nitrogen, the emulsifying agent are selected from following one or more materials：Phosphatide, Sucrose Fatty Acid Ester Fat acid esters, list, diglycerine fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, tween 20th, the content of polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent with Weight ratio meter is 0.05%~8%；The liposoluble substance A is selected from following one or more materials：Oleic acid, linoleic acid, leukotrienes, Medium chain triglyceride, diglyceride, middle long chain fatty acids, wherein liposoluble substance A content are more than 45% with weight ratio meter；Institute State liposoluble substance B and be selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant steroid Alkanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content are excellent using weight ratio meter as 0~30% Liposoluble substance B content is selected using weight ratio meter as 0.01%~30%；The leukotrienes includes alpha-linolenic acid or gamma-Linolenic acid, The middle long chain fatty acids include medium chain fatty acid or long chain fatty acids, and the emulsifying agent also includes its various model, specification, gathered Right, esterification degree, mono-/bis-ester, or its monomer component for including, the content of lecithin is more than 40% in the phosphatide；It is it is preferred that described Emulsifying agent is selected from phosphatide and following one or more materials：Sucrose fatty ester, list, diglycerine fatty acid ester, polyglycereol fat Acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, sapn 40th, sorbester p18, sorbester p38, sorbester p17；The wherein content of emulsifying agent is using weight ratio meter as 0.1%~4%, the content of preferred emulsifier Using weight ratio meter as 0.2%~3%；Its preparation method uses above-mentioned second of preparation method or the third preparation method.

Inventor surprisingly has found, hydrophily lipid composite provided by the invention, in water fluid, is shaken through shaking, can Emulsion is quickly formed, for example, by the operation for rolling of shaking, by hydrophily lipid composite of the present invention and water fluid in closing Mixed in container, such as in the beverage bottle using bottle cap closing, hydrophily lipid composite and water fluid are in a reservoir Cumulative volume is not higher than in 98% volume space of container total capacity, by way of hand shakes rolling, rolling 1~3 time of acutely shaking, this Invention lipid composite can form emulsion at once with water fluid, and the emulsion stands 5min, or even more than 10min, still Homogeneous, stable emulsion is kept, consumer or patient's allotment is very easy to and eats；In addition, the hydrophily lipid group Compound and water fluid are allocated to form emulsion after, even if after standing and being layered through the long period, through slight wobble, can still divide Dissipate for emulsion, can't influence to drink or eat.Inventor is shaking lipid composite provided by the invention and water fluid Under rolling effect, moment forms the process or technology of emulsion, is referred to as " oil-water wink mixes ".

It should be noted that whether observation emulsion is layered, it is so that the liquid level that lipid material swims in water fluid occurs On, and it is standard to form lipid material clearly released state occur with water fluid；In addition, in observation, it shall be noted that area Bubble present on the liquid level of other emulsion or foam and the essential distinction of emulsion layering；Generally, hydrophily lipid of the present invention Composition is forming emulsion with water fluid through cross to shake rolling, can all produce the bubble or foam of emulsion, and caused Bubble or floatation of foam are on the liquid level of emulsion, but the bubble of this floating or foam are not that emulsion is layered, this One phenomenon is it is noted that difference.

Further, the invention provides the user containing emulsifying agent and liquid aliphatic hydrophily lipid composite Method, it includes adding hydrophily lipid composite in water fluid, is shaken through shaking, form it into emulsion and further use, For example, it is preferable to the application method as the product for drinking the nutrition treatments such as ready-mixed oil, drinkable healthy oil；

Or further, the invention provides the application method of described hydrophily lipid composite, and it is included the present invention After described hydrophily lipid composite mixes with water fluid, shaken in the container of closing through shaking, become emulsion；

Wherein, the water fluid includes the liquid of water, water content more than 60%, or the aqueous solution containing ethanol；It is described to shake Shake, the frequency of at least 1 time rolling of shaking preferably was carried out in 1 second, and the time for rolling of shaking is no less than 1 second.

Further, the invention provides contain emulsifying agent and liquid aliphatic hydrophily lipid composite and water fluid Mixing preparation method, including will carry out after lipid composite and water fluid mixture shaking rolling and form emulsion, it is described Water fluid includes the liquid of water, water content more than 60%, or the aqueous solution containing ethanol.

On the other hand, it is provided by the invention containing emulsifying agent and liquid aliphatic hydrophily lipid composite, have quick Water emulsification performance, preferably by the hydrophilic lipid composite of the present invention and be deployed into emulsion using allotment bottle, particularly, with Following method of the method as the fast deployment of hydrophily lipid composite and water fluid into aqueous emulsion：By hydrophily lipid Composition is poured into allotment bottle with water fluid, and the weight ratio of wherein water fluid and hydrophily lipid composite is more than 3:1, it is excellent The weight ratio of water fluid and hydrophilic lipid composite is selected to be more than 10:1, make hydrophily lipid composite and water fluid Cumulative volume is no more than the 98% of allotment bottle capacity, tightens the lid of allotment bottle, is shaken with hand or manipulator by bottle is allocated in 1 second The frequency of at least 1 time is shaken, allotment bottle is shaken rolling no more than 10 seconds, allotment bottle is shaken rolling no more than 5 seconds, allotment bottle shakes During rolling, the distance of the allotment each displacement of bottle is not less than 10 centimetres, and moves the remaining space of mixed liquor to allotment bottle, preferably Move the remaining space of mixed liquor to allotment bottle and impact the lid of allotment bottle, you can form homogeneous emulsion, the milkiness Liquid stands 5min and keeps homogeneous milkiness liquid status at room temperature, is not layered；The allotment bottle, including vial with cover, Plastic bottle with cover, aluminium with cover-modeling carton, canister with cover, for example, macromolecule PET bottle, high-density polyethylene bottle Bottle, etc.；It is preferred that the volume of allotment bottle is not more than 3 liters, the volume for most preferably allocating bottle is not more than 3 liters, preferably allocates the appearance of bottle Product for 2.5 liters, 1.5 liters, 1 liter, 0.9 liter, 0.8 liter, 0.7 liter, 0.6 liter, 0.5 liter, 0.45 liter, 0.4 liter, 0.3 liter, 0.2 liter, 0.15 liter, 0.1 liter, 0.09 liter, 0.08 liter, 0.07 liter, 0.06 liter, 0.05 liter or 0.04 liter, etc.；The water fluid includes Water, water content are more than 60% liquid, or the aqueous solution containing ethanol.

For example, specifically, water fluid of the present invention includes but is not limited to the aqueous solution of water, carbohydrate（Example Such as monosaccharide and disaccharide, oligosaccharide, polysaccharide）, dietary fiber the aqueous solution（Such as inulin, FOS, polydextrose）, meals The aqueous suspension of fiber, animal emulsion, animal albumen powder emulsion, vegetable protein emulsion, the aqueous solution of probiotics or suspension, ammonia The aqueous solution, the aqueous solution, fruit juice, vegetable juice, the aqueous extract of plant, the aqueous solution or water of plant extracts of vitamin of base acid Turbid（Such as the water suspension of the aqueous solution of tealeaves or coffee, tealeaves or coffee）, ethanol water, homogenate diet, etc..

The present invention contains emulsifying agent and liquid aliphatic hydrophily lipid composite, has unexpected quick water and milk Change performance, be used for bringing great convenience and novel sense.

Hydrophily lipid composite of the present invention by shake shake, can rapidly or moment in water disperse, have soon The hydrophilic characteristic of speed.Further, the skill the invention provides described hydrophily lipid composite fast deployment into emulsion Art scheme.A kind of hydrophily lipid composite containing emulsifying agent, liposoluble substance A and liposoluble substance B, the emulsifying agent choosing From following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglyceryl fatty acid ester, the third two Alcohol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, The content of sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio It is calculated as 0.1%~6%；The liposoluble substance A is selected from following one or more materials：Oleic acid, linoleic acid, alpha-linolenic acid, γ-Asia Numb acid, medium chain triglyceride, diglyceride, middle long chain fatty acids, wherein liposoluble substance A content are more than with weight ratio meter 45%；The liposoluble substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, Vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, Plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0~ 30%, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, emulsion can be formed within 5 seconds, and And the emulsion standing at least 1min formed, homogeneous milkiness liquid status can be kept, are not layered, wherein water fluid and parent The weight ratio of water-based lipid composite is more than 3:1, the weight ratio of preferably water fluid and hydrophilic lipid composite is more than 10:1；

The water fluid, including：Water, water content are more than 60% liquid, or the aqueous solution containing ethanol；

The rolling of shaking, refers to the operating method by vibrating, rocking or rock, and mixture is produced motion, rolling in a reservoir Or/and the motion of collision impact, mixture is produced rolling of shaking with hand including the use of person, or, mixture is made using machine operation Generation is shaken rolling, for example with the operation of manipulator.

The speed of the rolling of shaking, the frequency of at least 1 time rolling of shaking preferably was carried out in 1 second；

The middle long chain fatty acids include medium chain fatty acid or long chain fatty acids；

Preferably, the content of the liposoluble substance B is using weight ratio meter as 0.01%~30%；

Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 4 seconds Turbid；

Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 3 seconds Turbid；

Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 2 seconds Turbid；

Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 1 second Turbid.

Hydrophily lipid composite of the present invention, belongs to lard type composition, for easy to use, more preferable absorption, Hydrophily lipid composite of the present invention is formed into emulsion in water base liquid to be very important.For example, this is sent out The bright healthy food or beverage mate for providing described hydrophily lipid composite as various water base liquid foods, preferably As homogenate diet, milk, beverage, the aqueous solution, fruit juice, coffee, liquid food, such as gruel, rice paste, batter, reconstituted food, wheat is such as reconstituted Piece, soaking milk powder, reconstitute coffee, reconstitute solid beverage, etc.；Drink ready-mixed oil preferably as what is allocated available for water, can drink Use healthy oil；More preferably emulsion is deployed into using water fluid to use.

Further, invention further provides contain hydrophily lipid composite of the present invention and water fluid Packaging compositions, the packaging compositions method that is deployed into emulsion.

A kind of packaging compositions, including hydrophily lipid composite is independently packed and combined one with water fluid Rise, the hydrophily lipid composite contains liquid aliphatic and emulsifying agent, and wherein liquid aliphatic is selected from following one or more things Matter：Medium chain triglyceride, alpha-linolenic acid, gamma-Linolenic acid, diglyceride, oleic acid, linoleic acid, middle long chain fatty acids, liquid aliphatic Content in hydrophily lipid composite is more than 45% with weight ratio meter；

Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol ester Fat acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, department Disk 40, sorbester p18, sorbester p38, sorbester p17, content of the emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.05%~ 8%；

The water fluid, 60% liquid, or the aqueous solution containing ethanol are more than selected from water, water content；

The weight ratio of the water fluid and hydrophily lipid composite is more than 3:1；

The volume summation of the water fluid and hydrophily lipid composite is not more than the container capacity of receiving water fluid 98%。

Above-mentioned packaging compositions, further contain liposoluble substance B, the liposoluble in the hydrophily lipid composite Property substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension life Plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol Ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein contents of the liposoluble substance B in hydrophily lipid composite are with weight Amount ratio is calculated as 0.01%~30%.

Specifically, various combinations provided by the invention, the hydrophily fat of specific composition, proportioning, preparation method, concocting method Based composition, the hydrophily lipid composite suitable for above-mentioned packaging compositions.

The packaging compositions, including hydrophily lipid composite of the present invention is independently wrapped with water fluid Fill and combine, such as form combination in same packing box or packaging bag, such as, by the only of lipid composite The form that vertical packaging fixed or packed external member by pasting fixed, label with the independent packaging of water fluid combines the shape together with Into packaging compositions, " form for fixing or packing external member by pasting fixed, label is combined ", refer to pass through glue The mode such as band or sticky glue combines the independent packaging of lipid composite and the independent packaging of water fluid；Or use fat The Product labelling of based composition, the Product labelling of water fluid, by active forces such as the binding of label, parcel, windings, by lipid The independent packaging of composition and the independent packaging of water fluid are combined；Or by the independent packaging of lipid composite and water The independent packaging of base fluid body is arranged to pack the mode of external member, combines, for example, setting one on the container of water fluid Individual groove, by the packing material card of lipid composite in a groove, formed packaging external member, or by lipid composite it is independent sealed in In the chamber of the The lid component of container, water fluid is sealed in container, and the The lid component of container is arranged on to the opening of container Place seals to container so that lipid composite is each independent sealed with water fluid, when in use, by the The lid component of container Open, discharge the lipid composite in The lid component, mixed with the water fluid in container, further, shaken by shaking to be formed Homogeneous emulsion；For example, the The lid component of described container, refers to be similar to disclosed in international publication WO2007/129126 Technical scheme.

Or in the packaging compositions, including by hydrophily lipid composite independent packaging of the present invention, and with Allotment bottle is present in same packaging housing unit simultaneously, and the allotment bottle is the empty bottle with lid, preferably allocates on bottle indicating The graduation mark of the amount in need for adding water fluid, in use, only need the packing material opening of hydrophily lipid composite, will Hydrophily lipid composite is poured into allotment bottle, adds water fluid, to facilitate allotment, rolling of shaking, makes aliphatic acid composition very Homogeneous emulsion is formed in water fluid well and is used, is also convenient for the hydrophily lipid group that user decides addition in its sole discretion The amount of the amount of compound and the water fluid added.

Or special situation is, packaging compositions of the present invention, in the packaging compositions, can not adjust With bottle, but it is labeled with the label of the packing material of hydrophily lipid composite and passes through the lipid composite with water fluid Mix in a reservoir and by mixed liquor shake and shake and obtain the content information of emulsion, and the bag of lipid composite of the present invention Fill the technology contents of composition, i.e. hydrophily lipid composite, and be labeled with its Product labelling and combine hydrophily lipid Thing shakes with the mixed merga pass of water fluid to shake and obtains the content of emulsion.

Combination, storage of the above-mentioned packaging compositions more convenient for lipid composite and water fluid, are more beneficial for lipid group The allotment of compound and water fluid uses, the method that described hydrophily lipid composite is deployed into emulsion with water fluid, Including：Hydrophily lipid composite is poured into the container for accommodating water fluid, wherein water fluid and hydrophily lipid group The weight ratio of compound is more than 3:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than the 98% of container capacity, The lid of container is tightened, bottle will be allocated in the frequency of shaking at least 1 time of being shaken in 1 second with hand or manipulator, container rolling of shaking is not surpassed Spend 10 seconds, container shake rolling when, the distance of each displacement of container is not less than 10 centimetres, and makes the residue of mixed liquor to container empty Between move and form emulsion, preferably container shake rolling when, make the mixed liquor move to the remaining space of container and impact to allocate bottle Lid；

Wherein hydrophily lipid composite includes any one hydrophily lipid composite of the present invention；

The container of the water fluid, selected from vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, gold with cover Belong to container, and the volume of container is not more than 3 liters.

Present invention also offers described hydrophily lipid composite be applied to medicine, special medicine purposes formula food, Health food, nutraceutical or cosmetics, etc., on the one hand, contain in the hydrophily lipid composite to health and The unrighted acid and fats health ingredients of rehabilitation effect, are particularly suitable for use in and prepare medicine, special medicine purposes is matched somebody with somebody Square food, health food, nutraceutical or cosmetics, on the other hand, hydrophily lipid composite of the invention belong to liquid, Grease type solvent can be used as, fat-soluble medicine is dissolved and can further be allocated, is dispersed in shape in water fluid Use, in favor of the oral of fat-soluble medicine, absorption and utilize, for example, fat-soluble medicine includes A Defu into emulsion Wei ester, tenofovir disoproxil, lutein ester, Co-Q10, etc..In addition, when being used for cosmetics, as moisturizing essential oil, skin care essence Oil, Hair-conditioning essential oil, or water is dissolved in as face, the moisturizing of skin, repairing cosmetics, and skin-nourishing oil breast, etc., use In the nursing to skin and beauty, etc..Particularly, hydrophily lipid composite of the present invention, as drinking ready-mixed oil, The health such as drinkable healthy oil, health care, the product of nutrition treatment.Particularly, the even of special medicine purposes formula food is being prepared Starch the application in meals.

Therefore, present invention also offers containing the emulsifying agent and liquid aliphatic hydrophily lipid composite by with water Base fluid body mix, and further through shake shake and be deployed into emulsion, prepare or allocate medicine, special medicine purposes formula food Application in terms of product, health food, nutraceutical or cosmetics, especially preparing or allocating the medicine being orally ingested immediately, spy Application in different medical usage formula food, health food, nutraceutical, or in the cosmetics prepared or allotment uses immediately In application, greatly facilitate user instant allotment, immediately use.

Present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid Close, through shake shake and be prepared into the application in emulsion.

Present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid Close, and further through shake shake and be deployed into emulsion, in the homogenate diet for preparing special medicine purposes formula food food should With.

Present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid Close, through shake shake and be prepared into emulsion, and be further used for canteen make in application, with emulsion replace canteen making in Water be applied to canteen make in, including but not limited to make steaming savor food, boil savor food, modulation wheaten foods, mix food it is all kinds of Application in food or reconstituted food beverage.

On the one hand, hydrophily lipid composite of the present invention, can provide beneficial for health and disease treatment Unrighted acid, such as nervonic acid, alpha-linolenic acid, gamma-Linolenic acid, DHA, EPA, arachidonic acid, etc., and fat-soluble Medicine or nutriment, such as vitamin E, medium chain triglyceride, phosphatide, vitamin A, vitamin D, lutein ester, Co-Q10, Etc.；On the other hand, emulsifying agent and liposoluble substance of the present invention have good pharmacology synergy, for health, especially It has good synergy in oral supplementation phosphatide, unrighted acid and fat-soluble medicine etc..Therefore, more enter One step, present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid Close, through shake shake and be prepared into the emulsion for being available for orally drinking, prepare preventing and treating cardiovascular and cerebrovascular disease medicine or Special food The application of aspect；Application in terms of preparing nutrition or protecting the medicine or Special food of cranial nerve；Moved back preparing preventing and treating nerve Application in the medicine of row disease；The risk caused by preparation reduction generation myocardial infarction, cerebral apoplexy or angiocardiopathy Applied in medicine；Improve myocardial ischemia and improvement cerebral ischemia, protection heart and brain cell, reducing blood lipid, preventing and treating cardiovascular and cerebrovascular disease preparing Application in sick, protection cardiovascular and cerebrovascular medicine；Application in terms of the medicine or Special food for the treatment of fatty liver is prepared；Making Application in terms of the medicine or Special food of standby fat-reducing；Application in terms of antifatigue medicine or Special food is prepared；Making Application in terms of the standby medicine or Special food that unrighted acid is provided；Or provide fat-soluble medicine or spy preparing Application in terms of different food.

Hydrophily lipid composite of the present invention, it can also be used to during canteen makes, made in any need of water Or in the various canteens of allotment, can be with the emulsion that hydrophily lipid composite of the present invention and water are deployed into come generation For application of the water in canteen making, the canteen thus made, not only supplemented with aliphatic acid and liquid aliphatic needed by human, and And produced canteen, the suitable salted cake fried in sesame oil taste of also light concentrated phase, be advantageous to improve appetite, it is often more important that, the mistake that canteen makes Journey, for consumers, on the one hand, be a kind of enjoyment, especially pass through oil-based materials and water-based material one or two second Shake rolling process, moment is changed into emulsion, drastically increases the desire drunk or fed of consumer, this from allotment diet Process, caused psychological desire contribute to the intake of the oil-based materials of health-nutrition of the present invention；On the other hand, by parent of the invention The process of aqueous lipid composition and water allotment, it is that a kind of tune canteen producer starts, beaten one's brains and the process with eye, especially will Oil-based materials and water-based material are changed into emulsion, drastically increase consumer's by the rolling process of shaking of one or two second, moment The desire drunk or fed, it is this to contribute to health-nutrition of the present invention from the process for allocating diet, caused psychological desire The intake of oil-based materials；In addition, this rolling of shaking（Vibrate and rock）Process can discharge pressure, what this process was brought is a kind of Pleasant mood, optimizes diet mood, and this state being in a cheerful frame of mind contributes to healthy diet, and it is strong to not only facilitate the present invention The effect of the oil-based materials of health nutrition is played, and can more improve the amount to beverage or homogenate diet, and drink rate is abandoned in reduction, is reduced and is wasted And pollution.

Hydrophily lipid composite provided by the invention, the product preparing mode that oil-water quickly mutually melts is realized, there is weight Big meaning.For beverage or homogenate diet, oil-based materials are independently packed with water-based material, and by both independent packaging groups It is combined, both is quickly mixed by way of shaking and shaking allotment when in use and form emulsion, this method causes Oil-based materials independently preserve with water-based material and significantly improve respective stability, without adding emulsion stabilizing agent, avoid Unrighted acid is degraded, and is greatly improved the stability of product, be ensure that quality, maintains good flavor and mouth Sense, also extends shelf life or shelf-life, is advantageous to the quality assurance and circulation of commodity.

Further healthy meaning is hydrophily lipid composite provided by the invention, can not only to bring consumer More health fat, such as medium chain triglyceride, omega-fatty acid, ω -6 aliphatic acid, phosphatide, arachidonic acid, vitamin E, the health such as vitamin A, vitamin D, CLA, phytosterol, nutrition, the material of disease prevention and cure class, such as protect the heart The cerebrovascular, improve intelligence, trophic nerve；And consumer is easier, more easily with beverage, homogenate diet, common canteen Mode obtain these materials highly beneficial to health, disease prevention and cure.

It is contemplated that hydrophily lipid composite provided by the invention, is advantageous to improve the existing eating habit of people, The canteen for being even advantageous to improve the mankind makes custom and canteen collocation theory.

It should be understood that, oral preparation needs that by the absorption of intestines and stomach blood of human body could be entered to reach physiology work With, the quality of oral absorption, the therapeutic effect of medicine is directly affected.According to the concept of pharmacy, bioavilability (Bioavailability) refer to preparation to be rapidly absorbed into sanguimotor producing level and utilize speed.

It is fast in water base liquid containing emulsifying agent, liposoluble substance compared to the preparation of other non-emulsified liquid types, the present invention Speed forms emulsion, has excellent water-oily dissolubility, is being absorbed for the oral formulations using liposoluble substance as active ingredient In terms of sanguimotor degree and speed, there is significant facilitation and meaning, this biology for liposoluble substance The raising of availability is significant.The absorption process that preparation enters after stomach and intestine, in two stages, i.e., scattered and gastrointestinal wall are inhaled Two stages are received, are scatter firstly the need of in gastric juice or intestinal juice, then contacts again and is attached to gastrointestinal wall and absorbed and entered Enter blood, the two stages can all influence absorbing and being good for for the liposoluble substance of unrighted acid and other healthy functions Kang Zuoyong performance, liposoluble substance is prepared as the good emulsion of water dispersible, the dissolution of liposoluble substance and scattered Speed is dramatically speeded up, and is substantially increased degree and rate of dispersion that it disperses in gastric juice or intestinal juice, is made liposoluble substance and stomach The contact of intestinal wall is more abundant, and the active ingredient for being attached to Gastrointestinal Wall Absorption and entering blood is also more abundant, and this is for fat-soluble The raising of the bioavilability of material is significant.For example, nervonic acid, DHA, EPA, phosphatidylserine, medium chain triglyceride Three esters, alpha-linolenic acid, gamma-Linolenic acid etc. are deployed into milkiness by hydrophily lipid composite provided by the invention and water fluid Liquid is drunk, its bioavilability（Bioavailability) it is obviously improved, there is highly significant effect.

Hydrophily lipid composite and its concocting method of the present invention, solve the shortcomings of prior art, have following Advantage：1st, grease-like composition, not aqueous, stability is good；2nd, there is outstanding hydrophily, can be mixed with water and disperse to form milkiness Liquid, be advantageous to edible and easy to operation；3rd, allotment is convenient, fast, by rolling of shaking in a reservoir, can be formed in 1~5 second homogeneous Emulsion, allocate or make the mood for bringing pleasure to diet, help to discharge pressure and healthy diet, optimize diet feelings Thread；4th, the bioavilability of functional fatty acid or liposoluble substance is improved；5th, the emulsion formed has preferable stability, More than 5min is stood, homogeneous, stable emulsion can be kept；6th, the emulsion formed is after being long placed in and being layered, through slight Rock, can still form homogeneous emulsion, be advantageous to user and drink or be orally ingested by phased manner.

For embodiment in the implementation process of the present invention, those of ordinary skill in the art are not departing from the present invention's Caused various embodiments and modification are obvious and are easy to perform on the basis of scope and spirits.It is logical Cross the following examples to be further elaborated with come application to the present invention etc., it is not intended that limit of the embodiment to the present invention System.

Embodiment 1, hydrophilic lipid composite, its preparation and concocting method, it is applied in combination.

Hydrophilic lipid composite, recipe quantity by weight percentage, contain respectively：

Wherein, the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil.

Its preparation method one, including：

(1) dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed Splitting or integrating dissipate it is uniform, or, first by other liposoluble substances, such as nervonic acid, DHA, arachidonic acid, phytosterin ester or phosphatide Acyl serine adds liquid aliphatic and it is dissolved completely in liquid aliphatic, adds emulsifying agent, is stirred, is uniformly dispersed；

(2) liquid prepared in (1) is placed in emulsion tank, heating makes fluid temperature be more than 45 DEG C, big in speed of agitator Under conditions of 500r/min, be stirred 3~25min of operation, then in 3~5min rapidly by liquid cooling to 25 DEG C with Under, stop stirring, stand；Or the liquid prepared in (1) is placed in emulsion tank, heating make fluid temperature for 45 DEG C with On, in homogenizer carry out pressure be 20~58MPa homogeneous, then in 3~5min rapidly by liquid cooling to 25 DEG C with Under, stop stirring；

(3) it is filling：Oily liquids is subjected to vacuum outgas, it is filling, sealing, packaging, examine, produce.

Or its preparation method two, including：

(2) liquid prepared in (1) is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps emulsion tank In pressure be more than 1.3 atmospheric pressure, and be stirred 3~25min of operation under conditions of speed of agitator is more than 300r/min, make The foam type grease thing rich in nitrogen of nontransparent shape is presented in oily liquids, stops stirring；

(3) it is filling：Will（2）The oily liquids of middle preparation is filling in container, further container is carried out to be filled with nitrogen, and make appearance Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces.

Or its preparation method three, including：

（2）Liquid aliphatic and liposoluble substance are mixed, stirring, its mixing is uniformly dispersed, obtain the mixing of liposoluble substance Thing, or, first other liposoluble substances, such as nervonic acid, DHA, arachidonic acid, phytosterin ester or phosphatidylserine are added Enter liquid aliphatic and it is dissolved completely in liquid aliphatic, be stirred, be uniformly dispersed；

（3）The premixing of emulsifying agent：Take 3~7 times of emulsifying agent and emulsifying agent weight（2）The mixing of the liposoluble substance of middle preparation Thing, it is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure, And stirred under conditions of speed of agitator is more than 300r/min, make oily liquids that the foam type rich in nitrogen of nontransparent shape be presented Foam-like is presented in grease thing, or grease, stops stirring；

(5) it is filling：Will（4）The oily liquids of middle preparation is filling in container, further container is carried out being filled with nitrogen and makes appearance Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces.

Fast deployment performance：The hydrophily lipid composite that any one in the present embodiment matches is poured into water fluid Allocate in bottle, the weight ratio of wherein water fluid and hydrophilic lipid composite is more than 10:1, make hydrophily lipid composite It is no more than the 98% of allotment bottle capacity with the cumulative volume of water fluid, tightens the lid of allotment bottle, bottle will be allocated with hand or manipulator Shake the frequency of at least 1 time in being shaken in 1 second, allotment bottle is shaken rolling at most 5 seconds, allotment bottle shake rolling when, allocate each displacement of bottle Distance be not less than 10 centimetres, and the remaining space of mixed liquor to allotment bottle move, preferably make mixed liquor to allocating bottle Remaining space moves and impacts the lid of allotment bottle, as stated above, you can form homogeneous emulsion, the emulsion is in room temperature Lower standing 5min is in still homogeneous emulsion, is not layered；The allotment bottle, it is vial with cover, plastic bottle with cover, band The aluminium of lid-modeling carton, canister with cover, for example, macromolecule PET bottle, high-density polyethylene bottle bottle, etc.；It is with cover be for Lid can be tightened and shake and shake the operation of allotment, the volume for preferably allocating bottle is not more than 3 liters, such as the appearance of preferred allotment bottle Product is 0.5 liter, and the aqueous-based liquid includes the liquid of water, water content more than 60%, or the aqueous solution containing ethanol, such as Including but not limited to animal emulsion, fruit juice, beverage made of fruits or vegetables, plant extraction liquid or beverage, carbohydrate solutions, vegetable protein drink The aqueous solution, etc. of material, the aqueous emulsion of animal milk powder, amino acid.

Embodiment 2, hydrophilic lipid composite, it is prepared and concocting method.

Wherein, the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil；Alpha-linolenic acid Donor plant grease separation from linseed oil, Purple Perilla Seed Oil, pumpkin seed oil, peony seed oil, eucommia ulmoides seed oil or oil and fat of sacha inchi；γ-Asia The donor grease separation of numb acid is from gamma-linolenic acid oil；Linoleic donor plant grease separation is from soybean oil, corn oil, peanut oil, sunflower Seed oil, olive oil, silybum marianum seed oil, pumpkin seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower Seed oil, grape-kernel oil, Suaeda salsa seed oil, wheat-germ oil, maize germ oil, smooth bark Lai wood fruit oil, rhus glabra oil, tree peony Seed oil, samara oil, imperial rice bran oil, tomato seed oil, Fructus Zanthoxyli oil, canola, Camellia oil (including tea seed oil, camellia seed oil or Tea oil), rice bran oil, shea butter, borage oil, capsicum seed oil, coconut oil or cottonseed oil；The donor plant grease separation of oleic acid is certainly Soybean oil, corn oil, peanut oil, sunflower oil, olive oil, pumpkin seed oil, silybum marianum seed oil, amygdalus pedunculata pall oil, palm oil, sesame Sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran oil, capsicum seed oil, granada seed oil, brucea fruit oil or coconut palm In seed oil；The donor vegetable and animals oils of nervonic acid include acer truncatum seed oil or shark oil；DHA donor vegetable and animals oils include DHA algal Oil, krill oil, fish oil or fish oil extract；EPA donor vegetable and animals oils include krill oil, fish oil or fish oil extract.

Preparation method：Its preparation method is with being preparation method one, preparation method two or the preparation method three-phase in embodiment 1 Together, the preparation method in embodiment 1 can be completely suitable for the present embodiment.

Allotment：The hydrophily lipid composite water fluid of any one proportioning is shaken to be deployed into milkiness by shaking Liquid.

Embodiment 3, hydrophilic lipid composite, it is prepared and concocting method.

Wherein, the phosphatide includes soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil；It is linoleic Donor plant grease separation is flat from soybean oil, corn oil, peanut oil, sunflower oil, olive oil, silybum marianum seed oil, pumpkin seed oil, long handle Peach oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, Suaeda salsa seed oil, wheat-germ oil, Maize germ oil, smooth bark Lai wood fruit oil, rhus glabra oil, peony seed oil, samara oil, imperial rice bran oil, tomato seed oil, Fructus Zanthoxyli oil, Canola, Camellia oily (including tea seed oil, camellia seed oil or tea oil), rice bran oil, capsicum seed oil, granada seed oil, crow courage Seed oil or coconut oil；The donor plant grease separation of oleic acid is from soybean oil, corn oil, peanut oil, sunflower oil, olive oil, pumpkin Oil, silybum marianum seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran Oil, capsicum seed oil or coconut oil.

Embodiment 4, hydrophilic lipid composite, it is prepared and concocting method.

Wherein, the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil；Alpha-linolenic acid Donor plant oil include linseed oil, Purple Perilla Seed Oil, pumpkin seed oil, peony seed oil, eucommia ulmoides seed oil or oil and fat of sacha inchi；γ-Asia The donor grease separation of numb acid is from gamma-linolenic acid oil；Linoleic donor plant grease separation is from soybean oil, corn oil, peanut oil, sunflower Seed oil, olive oil, silybum marianum seed oil, pumpkin seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower Seed oil, grape-kernel oil, Suaeda salsa seed oil, wheat-germ oil, maize germ oil, smooth bark Lai wood fruit oil, rhus glabra oil, tree peony Seed oil, samara oil, imperial rice bran oil, tomato seed oil, Fructus Zanthoxyli oil, canola, Camellia oil (including tea seed oil, camellia seed oil or Tea oil), rice bran oil, capsicum seed oil, granada seed oil, brucea fruit oil or coconut oil；The donor plant grease separation of oleic acid from soybean oil, Corn oil, peanut oil, sunflower oil, olive oil, pumpkin seed oil, silybum marianum seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, core Persic oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran oil, capsicum seed oil or coconut oil.

Embodiment 5, hydrophilic the lipid composite fast deployment performance and packaged combination of embodiment 2 to embodiment 4.

The hydrophilic lipid composite that any one is matched into embodiment 4 of Example 2, has good fast velocity modulation With performance.

Fast deployment performance：The hydrophily lipid composite that any one in embodiment matches and water fluid are poured into tune With in bottle, the weight ratio of wherein water fluid and hydrophilic lipid composite is more than 3:1, preferably water fluid with it is hydrophilic The weight ratio of lipid composite is more than 10:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than allotment bottle and hold The 50% of amount, the lid of allotment bottle is tightened, will allocate bottle in the frequency of shaking at least 1 time of being shaken in 1 second with hand or manipulator, make tune Shaken rolling at most 5 seconds with bottle, allotment bottle shake rolling when, the distance of the allotment each displacement of bottle is not less than 10 centimetres, and makes mixed liquor Moved to the remaining space of allotment bottle, preferably move the remaining space of mixed liquor to allotment bottle and impact the lid of allotment bottle, As stated above, you can form homogeneous emulsion, it is in still homogeneous emulsion that the emulsion stands 5min at room temperature, is not occurred Layering；The allotment bottle, is vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, canister with cover, example Such as, macromolecule PET bottle, high-density polyethylene bottle bottle, etc.；It is with cover to be to be able to tighten lid and shake to shake the behaviour of allotment Make, the volume for preferably allocating bottle is not more than 3 liters, such as the volume of preferred allotment bottle is 0.5 liter, and the aqueous-based liquid includes Water, water content are more than 60% liquid, or the aqueous solution containing ethanol, such as including but not limited to animal emulsion, fruit juice, fruit Vegetable beverage, plant extraction liquid or beverage, carbohydrate solutions or beverage, vegetable protein beverage, the aqueous emulsion of animal milk powder, ammonia Aqueous solution of base acid, etc..

Packaged combination：A kind of packaging compositions, including the hydrophily lipid composite that any one in embodiment is matched Independent packaging, and be present in simultaneously in same packing box or same packaging bag with allotment bottle, the allotment bottle is with lid The empty bottle of son；Or the water fluid of certain volume is pre-loaded with the allotment bottle, for aliphatic acid composition is directly added Enter to allocate bottle, shaken by shaking to form homogeneous emulsion；Or in the packaging compositions, hydrophily lipid composite it is only Vertical packaging is to be present in simultaneously in a packing box or packaging bag or fixed by pasting fixed, label with allotment bottle Mode form assembly packaging or Packaging Bottle equipped with hydrophily lipid composite or packaging bag with allotment bottle to pack The form of external member is fixed together, or the hydrophily fat matched in the packaging compositions containing any one in the present embodiment Based composition, and be embodied with by shaking shaking hydrophily lipid composite and water fluid to obtain emulsion on its label Content.The volume summation of wherein described water fluid and hydrophily lipid composite is not more than the container capacity for accommodating water fluid Or the 98% of allotment bottle capacity.

Packaged combination：The independent sealed lid structure in container of hydrophily lipid composite that any one in embodiment is matched In the chamber of part, water fluid is sealed in container, and opening of the The lid component of container installed in container is entered to container Row sealing so that lipid composite is each independent sealed with water fluid, when in use, the The lid component of container is opened, release The lipid composite gone out in The lid component, mix with the water fluid in container, further, shaken by shaking to form homogeneous milkiness Liquid；

Or the lipid composite in the chamber of the The lid component of container is injected into water in the form of a diameter of 0.4mm~2mm fluid column In base fluid body, such as gases at high pressure in the chamber for passing through the The lid component of container eject lipid composite, or pass through Piston pressurization, the mode injected eject lipid composite, lipid composite is mixed with water fluid, shake and shake and formed Emulsion, the water fluid include the liquid of water, water content more than 60%, or the aqueous solution containing ethanol.Wherein described water Base fluid body and 98% of the volume summation of hydrophily lipid composite no more than the container capacity for accommodating water fluid.

The hydrophily lipid composite of any proportioning, takes 1 gram of hydrophily lipid group in embodiment 6, embodiment 1~4 Compound, 2~150 milliliters of water fluid is added, shaken through shaking, in 5 seconds, or even emulsion can be formed in 1 second, also, The emulsion of formation is being stored at room temperature more than 5min, can keep being stabilized, and can keep homogeneous, stably, lamination does not occur；

Or pour into hydrophily lipid composite and water fluid in allotment bottle, its reclaimed water or water content are water base more than 60% The weight ratio of liquid and hydrophilic lipid composite is more than 3:1, the preferably weight of water fluid and hydrophilic lipid composite Amount is than being more than 10:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than the 70% of allotment bottle capacity, tighten tune Lid with bottle, bottle will be allocated in the frequency of shaking at least 2 times of being shaken in 1 second with hand or manipulator, allotment bottle is shaken rolling at most 5 seconds Clock, allotment bottle shake rolling when, the distance of the allotment each displacement of bottle is not less than 10 centimetres, and makes the residue of mixed liquor to allotment bottle empty Between move, preferably make mixed liquor to allotment bottle remaining space move and impact allocate bottle lid, as stated above, you can shape Into homogeneous emulsion, it is in still homogeneous emulsion that the emulsion stands 5min at room temperature, is not layered；The allotment bottle, Can be vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, canister with cover.

Any proportioning contains emulsifying agent and liquid aliphatic hydrophily lipid group in embodiment 7, embodiment 1~4 Compound by being mixed with water fluid, and further through shake shake and be deployed into emulsion, prepare or allocate medicine, special medicine Application in terms of purposes formula food, health food, nutraceutical or cosmetics.

Claims

1. a kind of packaging compositions, including hydrophily lipid composite is independently packed and combined one with water fluid Rise, the hydrophily lipid composite contains liquid aliphatic and emulsifying agent, and wherein liquid aliphatic is selected from following one or more things Matter：Medium chain triglyceride, alpha-linolenic acid, gamma-Linolenic acid, diglyceride, oleic acid, linoleic acid, middle long chain fatty acids, liquid aliphatic Content in hydrophily lipid composite is more than 45% with weight ratio meter；

2. packaging compositions according to claim 1, the liquid aliphatic be selected from medium chain triglyceride and it is following a kind of or Many kinds of substance：Oleic acid, linoleic acid, leukotrienes, diglyceride, middle long chain fatty acids, wherein medium chain triglyceride is in hydrophily fat Content in based composition is using weight ratio meter as 30%~99%.

3. packaging compositions according to claim 1, the emulsifying agent is selected from phosphatide and following one or more materials：Sugarcane Sugar fatty acid ester, list, diglycerine fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, Polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent Content is using weight ratio meter as 0.1%~4% in hydrophily lipid composite.

4. packaging compositions according to claim 1, the content of the lecithin in the phosphatide is more than 40%.

5. packaging compositions according to claim 1, further contain fat-soluble thing in the hydrophily lipid composite Matter B, the liposoluble substance B are selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, Vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, Plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B is in hydrophily lipid composite Content using weight ratio meter as 0.01%~30%.

6. packaging compositions according to claim 1, the hydrophily lipid composite is prepared using following methods：It is wrapped Include：

(1) dispensing：Emulsifying agent, liquid aliphatic and other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed Splitting or integrating dissipates uniform；

7. packaging compositions according to claim 1, the hydrophily lipid composite is prepared using following methods：It is wrapped Include：

8. hydrophily lipid composite is deployed into the side of emulsion with water fluid in the packaging compositions described in claim 1 Method, including：Hydrophily lipid composite is poured into the container for accommodating water fluid, makes hydrophily lipid composite and water base The cumulative volume of liquid is no more than the 98% of container capacity, tightens the lid of container, and bottle will be allocated in 1 second with hand or manipulator Shake and shake the frequency of at least 1 time, container rolling of shaking is no more than 10 seconds, container shake rolling when, the distance of each displacement of container is not less than 10 centimetres, and mixed liquor is moved to the remaining space of container and impact the lid of allotment bottle and form emulsion；

9. a kind of method that hydrophily lipid composite containing liquid aliphatic and emulsifying agent is deployed into emulsion with water fluid, Including：Hydrophily lipid composite and water fluid are poured into allotment bottle, wherein water fluid and hydrophily lipid composite Weight ratio be more than 3:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than the 98% of allotment bottle capacity, twist The lid of tight allotment bottle, bottle will be allocated in the frequency of shaking at least 1 time of being shaken in 1 second with hand or manipulator, allotment bottle is shaken rolling not More than 10 seconds, allotment bottle shake rolling when, allotment each displacement of bottle distance be not less than 10 centimetres, and make mixed liquor to allotment bottle Remaining space motion and form emulsion；

The emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, it is diglycerine fatty acid ester, poly- sweet Oil and fat acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn 20th, span 40, sorbester p18, sorbester p38, sorbester p17, content of the emulsifying agent in hydrophily lipid composite is with weight ratio meter For 0.05%~8%；

The liquid aliphatic is selected from following one or more materials：Oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, middle chain are sweet Oily three esters, diglyceride, middle long chain fatty acids, content of the liquid aliphatic in hydrophily lipid composite is with weight ratio meter More than 45%；

The allotment bottle, selected from vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, canister with cover, And the volume for allocating bottle is not more than 3 liters.

10. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the water The weight ratio of base fluid body and hydrophily lipid composite is more than 10:1.

11. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the tune Shaken with bottle and shake the time no more than 5 seconds.

12. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the tune With bottle shake rolling when, make mixed liquor to allotment bottle remaining space move and impact allocate bottle lid.

13. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the parent Further following one or more materials are selected from aqueous lipid composition containing liposoluble substance B, the liposoluble substance B： Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, CLA glycerine Ester, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, Wherein contents of the liposoluble substance B in hydrophily lipid composite is using using weight ratio meter as 0.01%~30%.

14. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the liquid Body fat is selected from medium chain triglyceride and following one or more materials：Oleic acid, linoleic acid, leukotrienes, diglyceride, middle long-chain The content of aliphatic acid, wherein medium chain triglyceride in hydrophily lipid composite is using weight ratio meter as 30%~99%.

15. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the breast Agent is selected from phosphatide and following one or more materials：Sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol fatty acid Ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, The content of sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.1%~ 4%。

16. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the parent Aqueous lipid composition is prepared using following methods, including：

(1) dispensing：Emulsifying agent, liquid aliphatic, liposoluble substance are weighed by formula, is settled to required output, is stirred, divides Dissipate uniform；

17. the method that hydrophily lipid composite according to claim 9 is deployed into emulsion with water fluid, the parent Aqueous lipid composition is prepared using following methods, including：

18. the method that the hydrophily lipid composite described in claim 9 is deployed into emulsion with water fluid, preparing or adjusting Application in terms of medicine, special medicine purposes formula food, health food, nutraceutical or cosmetics.