CN107594506A - The combination of hydrophily lipid composite and water fluid, it is prepared and concocting method and application - Google Patents
The combination of hydrophily lipid composite and water fluid, it is prepared and concocting method and application Download PDFInfo
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Abstract
The present invention is provided containing emulsifying agent and liquid aliphatic hydrophily lipid composite and its packaging compositions, allotment application method, hydrophily lipid composite has excellent hydrophily, it can quickly be leached in water and form homogeneous, stable emulsion, it is prepared by easy to operation and canteen, pass through the rolling that mixes, shakes, homogeneous emulsion can be formed in 1~5 second, be advantageous to quick, the convenient allotment of lipid composite and water fluid, the advantages of with allocating, using immediately immediately, it is also beneficial to oral absorption and the utilization of liposoluble constituent；Present invention also offers its application in terms of medicine, special medicine purposes formula food, health food or nutraceutical is prepared, and greatly facilitates the instant allotment of user, uses immediately.
Description
Technical field the present invention relates to a kind of healthy product composition, specifically hydrophilic lipid composite and water fluid
Combination, and preparation method thereof, its allotment uses and applies.
Healthy product composition of the present invention, including medicine, special medicine purposes formula food, health food, nutrition
Food, cosmetics etc., the composition specifically containing emulsifying agent, water-free liquid aliphatic class.
Background technology one side, it is well known that the lipid material including unrighted acid is complete with water
It is incompatible, however healthy product in use, generally require with the lipid material that health-nutrition acts on it is water miscible
Health-nutrition material uses simultaneously, and prior art is that lipid material and water fluid are prepared as into emulsion supply patient or special
Crowd uses, but this previously prepared emulsion, in order to keep the stability of emulsion, extend commercially available storage life, addition
There is the emulsifying agent of a large amount of even excess, while in order to keep the stability of unrighted acid, also added with substantial amounts of antioxidant, prevent
Rotten agent, and alkali compounds is used, such as the pH value of sodium hydroxide regulation emulsion, these are unfavorable for the oral suction of aliphatic acid
Receive, or even health risk can be brought；Furthermore unrighted acid and ester, as leukotrienes, linoleic acid, oleic acid, arachidonic acid,
CLA, conjugated linoleic acid glyceride, DHA, EPA, nervonic acid etc. are in aqueous mixed liquor, it is easy to and aoxidize, degrade,
Temperature especially more than 40 DEG C, meeting accelerated degradation, causes a large amount of losses of unrighted acid, and have a strong impact on composition
Quality safety.
On the other hand, lipid material, especially unrighted acid are very greasy when directly drinking and are difficult to
Receive；Therefore prior art is orally ingested by the way that unrighted acid is made into soft capsule, and this is unfavorable for being orally ingested very much
Convenience, be also unfavorable for being orally ingested for larger dose, nor be beneficial to oral absorption.
Chinese patent publication No. CN104397702A, CN104490773A, CN104397706A disclose containing phosphatide, its
The emulsion compositions of its liposoluble substance and water, it is emulsified by high-speed stirred, the process of homogeneous, make liposoluble substance with
Water forms homogeneous emulsion, is advantageous to edible and absorbs.Unfortunately, on the one hand, unrighted acid it is fat-soluble
Material is in aqueous mixed liquor, it is easy to aoxidizes, degrades, especially the temperature more than 40 DEG C, meeting accelerated degradation, causes insatiable hunger
With a large amount of losses of aliphatic acid, and the quality safety of composition is had a strong impact on.
Generally, water-free lipid composite, it has good stability, but water-free lipid composite, and its oiliness is strong,
Completely immiscible and swim on the water surface with water, stirring or rocking can not be such that lipid composite is well mixed with water, and this is for fat
The allotment of based composition is using totally unfavorable, in medical product or healthy food etc. in use, its use range critical constraints, especially
It is for needing lipid composite being well mixed with aqua, or needs lipid composite being deployed into nutraceutical/special
Homogenate diet that can be oral in medical usage formula food, is very difficult；Also, also to meet that user is quick, easy
Ground carries out the allotment with aqua, and deployed mixed liquor is in emulsion, and is not susceptible to macroscopic layering, is advantageous to eat
With and use.
In actual applications, water-free liquid aliphatic, it is being configured to be easy to the product shape being orally ingested with water fluid
, should especially in the practical applications such as nutraceutical, special medicine purposes formula food, medicine or Clinical practice is prepared during state
Meet following four condition：
1st, there is hydrophily, can be mixed with water fluid and disperse to form emulsion, to improve the greasy mouth that it is difficult to receive
Sense；
2nd, stir or rock in a reservoir with water fluid, homogeneous emulsion can be formed in a short period of time, such as 10
Homogeneous emulsion is formed in second, to ensure quick and convenience when preparing；
3rd, the emulsion formed with water fluid has preferable stability, is susceptible to significantly be layered, such as at least
Visible layering did not occurred in 1 minute, so that user has the longer time drunk or be orally ingested；
4th, the emulsion formed through slight wobble, can still form homogeneous emulsion, in favor of making after standing is layered
User drinks or is orally ingested by phased manner.
Clearly for water-free lipid composite, prior art can not meet this above-mentioned four conditions, typically will not
Aqueous lipid composite makes the preparation of soft capsule to use, and this strongly limits the intake demand of consumer or patient, example
Such as, the patient of EN support is needed for that can not be swallowed, this soft capsule preparation is that its tube feed can not be taken in
, it also limit oral absorption and the utilization of liposoluble substance.
The content of the invention has excellent hydrophily it is an object of the invention to provide a kind of, and in water fluid quickly
Leach and form the lipid composite and its concocting method of emulsion.This lipid composite has excellent hydrophily, both protects
Demonstrate,proved lipid composite production, storage transport, shelf life product quality, again be beneficial to adjusted when in use with water fluid
Match somebody with somebody, dissolve, can quickly and easily use.
The invention provides the hydrophily lipid composite containing liquid aliphatic and emulsifying agent, the lipid composite and water
After the mixing of base fluid body, shaken by shaking, emulsion can be formed.Further, present invention also offers its packaging compositions, preparation side
Method, its allotment are used and applied.
Liquid aliphatic of the present invention, it is defined as presenting the aliphatic acid or grease of liquid at normal temperatures and pressures, including it is full
And/or undersaturated aliphatic acid, saturation or undersaturated grease, the triglycerides of saturated or undersaturated aliphatic acid, saturation or not
The diglyceride of the aliphatic acid of saturation, such as including but not limited to oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, glycerine two
Ester, middle long chain fatty acids, etc..
The present invention provides the hydrophily lipid composite containing emulsifying agent, liposoluble substance A and liposoluble substance B, described
Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol fatty acid
Ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40,
The content of sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier with
Weight ratio meter is 0.1%~6%；The liposoluble substance A is selected from following one or more materials：Oleic acid, linoleic acid, leukotrienes,
Medium chain triglyceride, diglyceride, middle long chain fatty acids, wherein liposoluble substance A content are more than 45% with weight ratio meter；Institute
State liposoluble substance B and be selected from following one or more materials：Nervonic acid (NA), DHA (22 carbon six
Olefin(e) acid), EPA (eicosapentaenoic acid), arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugation it is sub-
Olein, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, polyenoid phosphorus
Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0~30%, preferably described liposoluble substance B content with
Weight ratio meter is 0.01%~30%；For the content of the liposoluble substance B using weight ratio meter as 0~30%, expression is free of fat-soluble thing
Matter B contains 30% liposoluble substance B to highest；The leukotrienes includes alpha-linolenic acid or gamma-Linolenic acid, the middle long-chain fat
Acid includes medium chain fatty acid or long chain fatty acids.
Liposoluble substance A and liposoluble substance B of the present invention are fatty acid or liposoluble substance, typically from plant
Extracted in thing oil or animal oil, or from vegetable oil or animal oil（Such as fish oil, krill oil）Further closed again after middle extraction
Into compound or grease, for example, lecithin extracts from soybean oil or yolk, phosphatidylserine be with lecithin and
Serine is raw material, after phosphatide enzymatic conversion reaction, is made after purification；For another example phytosterol is included from soybean oil, dish
The cupreol that is extracted in seed oil, corn oil, sunflower oil, Tall oil, campesterol, stigmasterol etc.；
On the other hand, liposoluble substance A or liposoluble substance B of the present invention, it will usually be present in the ratio of certain content
In grease, liposoluble substance A or liposoluble substance B of the present invention can also be to contain the liposoluble substance A or fat-soluble
The vegetable oil or animal oil of substance B, or the chemical combination for further synthesizing or fermenting again after being extracted from vegetable oil or animal oil
Thing or grease are applied to the present invention.For example, Purple Perilla Seed Oil of the alpha-linolenic acid content more than 30%, linseed oil, peony seed oil, U.S.
The donor of rattan fruit oil or eucommia ulmoides seed oil as alpha-linolenic acid, applied to the present invention；Gamma -linolenic acid content is more than 8% γ-flax
Donor of the acid lipid as gamma-Linolenic acid, applied to the present invention；
For example, the soybean oil of oleic acid or linoleic acid content more than 40%, corn oil, peanut oil, sunflower oil, olive oil, milk thistle
Seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran oil, chilli seed
Oil, Fructus Zanthoxyli oil, canola, coconut oil, cottonseed oil, wheat-germ oil, eucommia ulmoides seed oil, tomato seed oil, silybum marianum seed oil, south
Melon seeds oil, krill oil, Camellia oil, including tea seed oil, camellia seed oil or tea oil, amygdalus pedunculata pall oil, smooth bark Lai wood fruit oil, salt
Ground common seepweed seeds oil, oil and fat of sacha inchi, rhus glabra oil, peony seed oil, samara oil, imperial rice bran oil, granada seed oil, brucea fruit oil, see the moon
Careless oil, blackcurrant oil, shea butter, borage oil, Litsea cubeba oil, pine-seed oil, hemp-seed oil, nut oil, canola oil or ginger
Oil is used as oleic acid or linoleic donor, applied to the present invention；
For example, contain the medium chain fatty acid more than 11%, the long chain fatty acids more than 10%, middle length in middle long chain fatty acids edible oil
The donor of long chain fatty acids, medium chain fatty acid or long chain fatty acids during chain fatty acid edible oil can be used as, applied to the present invention；
For example, acer truncatum seed oil or shark oil donor as nervonic acid of the neural acid content 3%~8%, applied to the present invention；
For example, DHA algal oil donor as DHA of the DHA content 3%~6%, applied to the present invention, DHA content is 3%~15%
Donor as DHA of fish oil or fish oil extract, applied to the present invention, confession of krill oil of the DHA content more than 3% as DHA
Body, applied to the present invention；
For example, soybean lecithin of the total phospholipids content more than 35%, krill oil, soybean lecithin, yolk phospholipid, egg yolk lecithin are made
For the donor of phosphatide, applied to the present invention.
Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B
Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather
Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn
20th, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent preferably emulsifies using weight ratio meter as 0.05%~8%
The content of agent is using weight ratio meter as 0.1%~6%；The liposoluble substance A is selected from medium chain triglyceride and following one or more
Material：Oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, diglyceride, middle long chain fatty acids, wherein medium chain triglyceride exist
Content in hydrophily lipid composite is using weight ratio meter as 30%~99%, and preferably the content of medium chain triglyceride is with weight ratio meter
For 40%~99%, preferably the content of medium chain triglyceride is using weight ratio meter as 45%~98%；The liposoluble substance B is selected from following
One or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA,
Conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol,
Polyene Phosphatidylcholine, wherein liposoluble substance B content are using weight ratio meter as 0~30%, preferred liposoluble substance B content
Using weight ratio meter as 0.01%~30%；The middle long chain fatty acids include medium chain fatty acid or long chain fatty acids, the emulsifying agent
Also include its various model, specification, the degree of polymerization, esterification degree, mono-/bis-ester, or its monomer component for including, the phosphatide include ovum
Phosphatide, phosphatidyl-ethanolamine, phosphatidylinositols or phosphatidyl glycerol；
The content of the liposoluble substance B is using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight ratio
Be calculated as 0.05%~25%, preferably liposoluble substance B content using weight ratio meter as 0.01%, 0.02%, 0.03%, 0.04%,
0.05%、0.06%、0.07%、0.08%、0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、
1%、1.1%、1.2%、1.3%、1.4%、1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、
2.5%、2.6%、2.7%、2.8%、2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、
4.1%、4.2%、4.3%、4.4%、4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、
5.6%、5.7%、5.8%、5.9%、6%、6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、
7.2%、7.3%、7.4%、7.5%、7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、8.5%、8.6%、
8.7%、8.8%、8.9%、9%、9.1%、9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、11%、12%、
13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%。
Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B
Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather
Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn
20th, the content of span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%；The liposoluble
Property substance A is selected from leukotrienes and following one or more materials：Oleic acid, linoleic acid, medium chain triglyceride, diglyceride, middle length
The content of chain fatty acid, wherein leukotrienes in hydrophily lipid composite is using weight ratio meter as 30%~99%；It is described fat-soluble
Substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin
D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester,
Rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content are described using weight ratio meter as 0.01%~30%
Leukotrienes includes alpha-linolenic acid or gamma-Linolenic acid.
Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B
Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather
Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn
20th, the content of span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent in hydrophily lipid composite is with weight ratio meter
For 0.05%~8%；The liposoluble substance A is selected from linoleic acid and following one or more materials：Oleic acid, alpha-linolenic acid, γ-Asia
Numb acid, medium chain triglyceride, diglyceride, middle long chain fatty acids, content of its Linoleic acid in hydrophily lipid composite
Using weight ratio meter as 30%~99%；The liposoluble substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, flower
Raw tetraenoic acid, vitamin E, vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, plant
Thing sterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B
Content is using weight ratio meter as 0.01%~30%.
Further, the present invention provides the hydrophily lipid group containing emulsifying agent, liposoluble substance A and liposoluble substance B
Compound, the emulsifying agent are selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, gather
Fatty acid glyceride, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, sapn
20th, the content of span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%；The liposoluble
Property substance A is selected from oleic acid and following one or more materials：It is linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, medium chain triglyceride, sweet
Oily diester, middle long chain fatty acids, wherein content of the oleic acid in hydrophily lipid composite is using weight ratio meter as 30%~99%；Institute
State liposoluble substance B and be selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin
A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant steroid
Alkanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0.01%~
30%。
Further specifically, present invention offer is a kind of to contain the hydrophilic of emulsifying agent, medium chain triglyceride and liposoluble substance A
Property lipid composite, the liposoluble substance A selected from oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, middle long chain fatty acids,
One or more in diglyceride, wherein medium chain triglyceride and liposoluble substance A content are more than 45% with weight ratio meter,
The content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, most preferably
The content of emulsifying agent is using weight ratio meter as 0.3%~2.5%.
Further specifically, present invention offer is a kind of to contain the hydrophilic of emulsifying agent, medium chain triglyceride and liposoluble substance B
Property lipid composite, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension
Raw plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol
One or more in ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein the content of medium chain triglyceride is with weight ratio meter
For 60%~99.5%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as
0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight
Than being calculated as 0.05%~25%, preferably liposoluble substance B content using weight ratio meter as 0.01%, 0.02%, 0.03%, 0.04%,
0.05%、0.06%、0.07%、0.08%、0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、
1%、1.1%、1.2%、1.3%、1.4%、1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、
2.5%、2.6%、2.7%、2.8%、2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、
4.1%、4.2%、4.3%、4.4%、4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、
5.6%、5.7%、5.8%、5.9%、6%、6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、
7.2%、7.3%、7.4%、7.5%、7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、8.5%、8.6%、
8.7%、8.8%、8.9%、9%、9.1%、9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、11%、12%、
13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%。
Specifically, the present invention provide it is a kind of containing emulsifying agent, nervonic acid, liposoluble substance A hydrophily lipid composite,
The liposoluble substance A is in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
One or more, liposoluble substance A content are more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~
8%, for the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of nervonic acid is excellent using weight ratio meter as 0.01%~30%
Select the content of nervonic acid using weight ratio meter as 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%,
0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、1%、1.1%、1.2%、1.3%、1.4%、
1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、2.5%、2.6%、2.7%、2.8%、
2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、4.1%、4.2%、4.3%、4.4%、
4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、5.6%、5.7%、5.8%、5.9%、6%、
6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、7.2%、7.3%、7.4%、7.5%、
7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、8.5%、8.6%、8.7%、8.8%、8.9%、9%、9.1%、
9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、11%、12%、13%、14%、15%、16%、17%、18%、
19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、30%。
Specifically, the present invention provide it is a kind of containing emulsifying agent, DHA, liposoluble substance A hydrophily lipid composite, institute
State one of liposoluble substance A in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
Kind or it is a variety of, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~
8%, the content of preferred emulsifier is 0.1%~6%, DHA content using weight ratio meter as 0.01%~30% using weight ratio meter, preferably
DHA content is using weight ratio meter as 0.04%~25%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, EPA, liposoluble substance A hydrophily lipid composite, institute
State one of liposoluble substance A in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
Kind or it is a variety of, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as 0.05%~
8%, the content of preferred emulsifier is 0.1%~6%, EPA content using weight ratio meter as 0.01%~30% using weight ratio meter, preferably
EPA content is using weight ratio meter as 0.04%~25%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, arachidonic acid, liposoluble substance A hydrophily lipid group
Compound, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
In one or more, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as
0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, arachidonic content using weight ratio meter as
0.01%~30%, preferably arachidonic content is using weight ratio meter as 0.04%~25%.
Specifically, the present invention provides a kind of hydrophily lipid combination containing emulsifying agent, vitamin E, liposoluble substance A
Thing, the liposoluble substance A is in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
One or more, liposoluble substance A content is more than 45% with weight ratio meter, and the content of emulsifying agent is using weight ratio meter as 0.05%
~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of vitamin E using weight ratio meter as 0.01%~
30%, preferred vitamin E content are using weight ratio meter as 0.04%~25%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, CLA, liposoluble substance A hydrophily lipid group
Compound, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
In one or more, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as
0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of CLA using weight ratio meter as
0.01%~25%, preferably the content of CLA is using weight ratio meter as 0.04%~20%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, conjugated linoleic acid glyceride, liposoluble substance A hydrophily
Lipid composite, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, sweet
One or more in oily diester, liposoluble substance A content are more than 45% with weight ratio meter, and the content of emulsifying agent is with weight ratio
0.05%~8% is calculated as, the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, and the content of conjugated linoleic acid glyceride is with weight
Amount ratio is calculated as 0.01%~25%, and preferably the content of conjugated linoleic acid glyceride is using weight ratio meter as 0.04%~20%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, phosphatidylserine, liposoluble substance A hydrophily lipid
Composition, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, glycerine two
One or more in ester, liposoluble substance A content are more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as
0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of phosphatidylserine using weight ratio meter as
0.01%~30%, preferably the content of phosphatidylserine is using weight ratio meter as 0.04%~25%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, Polyene Phosphatidylcholine, liposoluble substance A hydrophily fat
Based composition, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, glycerine
One or more in diester, liposoluble substance A content are more than 45% with weight ratio meter, and the content of emulsifying agent is with weight ratio meter
For 0.05%~8%, the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, and the content of Polyene Phosphatidylcholine is with weight ratio
0.01%~25% is calculated as, preferably the content of Polyene Phosphatidylcholine is using weight ratio meter as 0.04%~25%.
Specifically, the present invention provides a kind of hydrophily lipid combination containing emulsifying agent, phytosterol, liposoluble substance A
Thing, the liposoluble substance A is in oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
One or more, liposoluble substance A content is more than 45% with weight ratio meter, and the content of emulsifying agent is using weight ratio meter as 0.05%
~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of phytosterol using weight ratio meter as 0.01%~
30%, the content of preferred plant sterol is using weight ratio meter as 0.04%~25%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, phytosterin ester, liposoluble substance A hydrophily lipid group
Compound, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, diglyceride
In one or more, liposoluble substance A content is more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as
0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of phytosterin ester using weight ratio meter as
0.01%~30%, the content of preferred plant sterol ester is using weight ratio meter as 0.05%~26%.
Specifically, the present invention provide it is a kind of containing emulsifying agent, plant stanol ester, liposoluble substance A hydrophily lipid
Composition, the liposoluble substance A is selected from oleic acid, linoleic acid, leukotrienes, medium chain triglyceride, middle long chain fatty acids, glycerine two
One or more in ester, liposoluble substance A content are more than 45% with weight ratio meter, the content of emulsifying agent using weight ratio meter as
0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%, the content of plant stanol ester using weight ratio meter as
0.01%~30%, the content of preferred plant stanol ester is using weight ratio meter as 0.04%~25%.
Particularly, the present invention provides a kind of hydrophily lipid composite, containing leukotrienes, emulsifying agent, liposoluble substance B,
The liposoluble substance B is selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane
One or more in alcohol, Polyene Phosphatidylcholine, the leukotrienes include alpha-linolenic acid or gamma-Linolenic acid, wherein leukotrienes
Content using weight ratio meter as 45%~99.5%, using weight ratio meter as 0.05%~8%, preferred emulsifier contains the content of emulsifying agent
Amount is using weight ratio meter as 0.3%~2.5%, and liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferably fat-soluble thing
Matter B content using weight ratio meter as 0.05%~20%, preferably liposoluble substance B content using weight ratio meter as 0.01%, 0.02%,
0.03%、0.04%、0.05%、0.06%、0.07%、0.08%、0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、
0.8%、0.9%、1%、1.1%、1.2%、1.3%、1.4%、1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、
2.3%、2.4%、2.5%、2.6%、2.7%、2.8%、2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、
3.8%、3.9%、4%、4.1%、4.2%、4.3%、4.4%、4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、
5.4%、5.5%、5.6%、5.7%、5.8%、5.9%、6%、6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、
6.9%、7%、7.1%、7.2%、7.3%、7.4%、7.5%、7.6%、7.7%、7.8%、7.9%、8%、8.1%、8.2%、8.3%、8.4%、
8.5%、8.6%、8.7%、8.8%、8.9%、9%、9.1%、9.2%、9.3%、9.4%、9.5%、9.6%、9.7%、9.8%、9.9%、10%、
11%、12%、13%、14%、15%、16%、17%、18%、19%、20%、21%、22%、23%、24%、25%、26%、27%、28%、29%、
30%。
The present invention provides a kind of hydrophily lipid composite, contains linoleic acid, emulsifying agent, liposoluble substance B, the liposoluble
Property substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugation
Glyceryl linoleate, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, polyenoid
One or more in phosphatidyl choline, wherein linoleic content is using weight ratio meter as 45%~99%, the content of emulsifying agent with
Weight ratio meter is 0.05%~8%, and the content of preferred emulsifier is using weight ratio meter as 0.3%~2.5%, liposoluble substance B content
Using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content is preferably fat-soluble using weight ratio meter as 0.04%~25%
The content of substance B is using weight ratio meter as 0.06%~23%.
The present invention provides a kind of hydrophily lipid composite, described fat-soluble containing oleic acid, emulsifying agent, liposoluble substance B
It is sub- that substance B is selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, conjugation
Olein, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, polyenoid phosphorus
The content of one or more in phosphatidylcholine, wherein oleic acid is using weight ratio meter as 45%~99%, and the content of emulsifying agent is with weight
Than being calculated as 0.05%~8%, the content of preferred emulsifier is using weight ratio meter as 0.3%~2.5%, and liposoluble substance B content is with weight
Amount ratio is calculated as 0.01%~30%, and preferably liposoluble substance B content is using weight ratio meter as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains medium chain triglyceride, emulsifying agent, liposoluble substance B, institute
State liposoluble substance B and be selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane
The content of one or more in alcohol, Polyene Phosphatidylcholine, wherein medium chain triglyceride using weight ratio meter as 40%~99.5%,
For the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier is fat-soluble using weight ratio meter as 0.1%~6%
The content of substance B using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~
25%。
The present invention provides a kind of hydrophily lipid composite, contains diglyceride, emulsifying agent, liposoluble substance B, the fat
Soluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, CLA, altogether
It is conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkanol, more
Using weight ratio meter as 45%~99%, emulsifying agent contains the content of one or more in alkene phosphatidyl choline, wherein diglyceride
Amount using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.3%~2.5%, liposoluble substance B's
Content is using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is using weight ratio meter as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains middle long chain fatty acids, emulsifying agent, liposoluble substance B, institute
State liposoluble substance B and be selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane
One or more in alcohol, Polyene Phosphatidylcholine, wherein the content of middle long chain fatty acids is using weight ratio meter as 45%~99%, it is newborn
For the content of agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier is fat-soluble using weight ratio meter as 0.3%~2.5%
The content of substance B using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~
20%。
The present invention provides a kind of hydrophily lipid composite, contains oleic acid, linoleic acid, emulsifying agent, liposoluble substance B, institute
State liposoluble substance B and be selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane
One or more in alcohol, Polyene Phosphatidylcholine, wherein oleic acid and linoleic total content using weight ratio meter as 45%~99%,
For the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier is fat-soluble using weight ratio meter as 0.1%~6%
The content of substance B using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as 0.05%~
20%。
The present invention provides a kind of hydrophily lipid composite, containing leukotrienes, linoleic acid, emulsifying agent, liposoluble substance B,
The liposoluble substance B is selected from the sub- oil of nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats alkane
The total content of one or more in alcohol, Polyene Phosphatidylcholine, wherein linolenic and linoleic using weight ratio meter as 45%~
99%, the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is using weight ratio meter as 0.1%~6%, fat
Soluble substance B content is using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is using weight ratio meter as 0.05%
~20%.
The present invention provides a kind of hydrophily lipid composite, contains leukotrienes, medium chain triglyceride, emulsifying agent, fat-soluble
Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether
Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran
The total content of one or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein leukotrienes and medium chain triglyceride is with weight
Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as
0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight
Than being calculated as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains linoleic acid, medium chain triglyceride, emulsifying agent, fat-soluble
Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether
Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran
The total content of one or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, its Linoleic acid and medium chain triglyceride is with weight
Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as
0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight
Than being calculated as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, containing medium chain triglyceride, linoleic acid, leukotrienes, emulsifying agent,
Liposoluble substance B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension life
Plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol
One or more in ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein medium chain triglyceride, linoleic acid plus linolenic acid
Total content using weight ratio meter as 45%~99%, using weight ratio meter as 0.05%~8%, preferred emulsifier contains the content of emulsifying agent
Amount is using weight ratio meter as 0.1%~6%, and liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferred liposoluble substance
B content is using weight ratio meter as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains medium chain triglyceride, leukotrienes, linoleic acid, oleic acid, breast
Agent, liposoluble substance B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin
A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant steroid
One or more in alkanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein medium chain triglyceride, leukotrienes, sub- oil
For the total content of acid and oleic acid using weight ratio meter as 45%~99%, the content of emulsifying agent is preferably newborn using weight ratio meter as 0.05%~8%
The content of agent is using weight ratio meter as 0.1%~6%, and liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferred fat
Soluble substance B content is using weight ratio meter as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, containing medium chain triglyceride, middle long chain fatty acids, emulsifying agent,
Liposoluble substance B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension life
Plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol
One or more in ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein medium chain triglyceride and middle long chain fatty acids
Total content is using weight ratio meter as 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, the content of preferred emulsifier
Using weight ratio meter as 0.1%~6%, liposoluble substance B content is using weight ratio meter as 0.01%~30%, preferably liposoluble substance B
Content using weight ratio meter as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains medium chain triglyceride, diglyceride, emulsifying agent, liposoluble
Property substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D,
CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice
The total content of one or more in chaff fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein medium chain triglyceride and diglyceride with
Weight ratio meter is 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio
0.1%~6% is calculated as, liposoluble substance B content is using weight ratio meter as 0.01%~30%.
The present invention provides a kind of hydrophily lipid composite, contains leukotrienes, diglyceride, emulsifying agent, liposoluble substance
It is sub- that B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Oleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats
The total content of one or more in alkanol, Polyene Phosphatidylcholine, wherein leukotrienes and diglyceride is using weight ratio meter as 45%
~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%,
Liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as
0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains diglyceride, linoleic acid, emulsifying agent, liposoluble substance
It is sub- that B, the liposoluble substance B are selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, conjugation
Oleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran fats
One or more in alkanol, Polyene Phosphatidylcholine, wherein diglyceride and linoleic total content are using weight ratio meter as 45%
~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as 0.1%~6%,
Liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content using weight ratio meter as
0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains diglyceride, linoleic acid, leukotrienes, emulsifying agent, liposoluble
Property substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D,
CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice
One or more in chaff fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein diglyceride, linoleic acid plus linolenic acid total content with
Weight ratio meter is 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio
Be calculated as 0.1%~6%, liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content with
Weight ratio meter is 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains middle long chain fatty acids, diglyceride, emulsifying agent, liposoluble
Property substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D,
CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice
One or more in chaff fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein the total content of middle long chain fatty acids and diglyceride with
Weight ratio meter is 45%~99%, and the content of emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio
Be calculated as 0.1%~6%, liposoluble substance B content using weight ratio meter as 0.01%~30%, preferably liposoluble substance B content with
Weight ratio meter is 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains leukotrienes, middle long chain fatty acids, emulsifying agent, fat-soluble
Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether
Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran
One or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, wherein leukotrienes and the total content of middle long chain fatty acids are with weight
Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as
0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight
Than being calculated as 0.05%~20%.
The present invention provides a kind of hydrophily lipid composite, contains linoleic acid, middle long chain fatty acids, emulsifying agent, fat-soluble
Substance B, the liposoluble substance B be selected from nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, vitamin D, altogether
Conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant stanol ester, rice bran
The total content of one or more in fatty alkyl alcohol, Polyene Phosphatidylcholine, its Linoleic acid and middle long chain fatty acids is with weight
Than being calculated as 45%~99%, the content of emulsifying agent using weight ratio meter as 0.05%~8%, the content of preferred emulsifier using weight ratio meter as
0.1%~6%, liposoluble substance B content are using weight ratio meter as 0.01%~30%, and preferably liposoluble substance B content is with weight
Than being calculated as 0.05%~20%.
Emulsifying agent of the present invention is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerol fat
Fat acid esters, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, tell
Temperature 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.05%~
8%, the content of preferred emulsifier is using weight ratio meter as 0.1%~6%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.07%~7%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.1%~6%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.2%~5%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.3%~4%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.4%~3.5%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.5%~3%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.6%~2.5%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.75%~2%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.8%~1.8%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.85%~1.7%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.9%~1.6%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.95%~1.5%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 1.0%~1.4%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.4%~1.6%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.5%~1.5%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.6%~1.4%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.7%~1.3%；
Preferably, in the hydrophily lipid composite, the content of emulsifying agent is using weight ratio meter as 0.8%~1.2%.
Wherein, the emulsifying agent also includes its various model, specification, the degree of polymerization, esterification degree, mono-/bis-ester, or it is included
Monomer component.Specifically, phosphatide includes but is not limited to lecithin, phosphatidyl-ethanolamine, phosphatidylinositols or phosphatidyl glycerol, it is excellent
Choosing, the lecithin in the phosphatide（That is phosphatidyl choline）Content be more than 40%, the lecithin in preferably described phosphatide contains
Amount is more than 50%；It is preferred that the content of the lecithin in the phosphatide is more than 60%；Sucrose fatty ester includes but is not limited to its S-1 extremely
S-16 various models；Single, diglycerine fatty acid ester includes but is not limited to single, bi-tristearin, list, double oleics
Ester, list, dilaurate glyceride, list, dilinoleic acid glyceride, list, double glyceryl linolenates, list, double tripalmitins,
It is single, double Compritol 888 ATOs；Polyglyceryl fatty acid ester includes but is not limited to polyglycerol stearate, Unigly GO 102S, poly- sweet
Oily laurate, the dimer of polyglyceryl myristate or POGE-A, trimer, tetramer, hexamer, nine gather
Thing, etc., such as including but not limited to three polyglycerol stearates, three Unigly GO 102Ss, three polyglyceryl laurates, trimerization
Glycerine myristate ester, three POGE-As, four polyglycerol stearates, four Unigly GO 102Ss, four polyglycereol bays
Acid esters, four polyglyceryl myristates, four POGE-As, two polyglycerol stearates, two Unigly GO 102Ss, dimerization
Glycerol monolaurate, two polyglyceryl myristates, two POGE-As, six polyglycerol stearates, nine polyglycereol are hard
Resin acid ester, etc.；It is stearic that methyl glycol fatty acid ester includes but is not limited to propylene glycol oleate, propane diols linoleate, propane diols
Acid esters, etc.；Lactic acid fatty glyceride includes but is not limited to oleic acid, linoleic acid, stearic acid, linolenic glyceride lactate,
Etc..
Preferably, the emulsifying agent is phosphatide, and the wherein content of phosphatide is using weight ratio meter as 0.2%~3.5%, preferred phosphatide
Content using weight ratio meter as 0.5%~2.5%.
Preferably, the emulsifying agent is selected from phosphatide and following one or more materials：Sucrose fatty ester, list, diglycerol
Fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60,
Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.1%~
4%, the content of preferred emulsifier is using weight ratio meter as 0.2%~3%.
Preferably, the emulsifying agent includes sucrose fatty ester and following one or more materials：Phosphatide, list, diglycerol
Fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60,
Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~
5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.
Preferably, the emulsifying agent includes single, diglycerine fatty acid ester and following one or more materials：Phosphatide, sucrose
Fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60,
Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~
5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.
Preferably, the emulsifying agent includes polyglyceryl fatty acid ester and following one or more materials：Phosphatide, sucrose fat
Acid esters, list, diglycerine fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60,
Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~
5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.
Preferably, the emulsifying agent includes methyl glycol fatty acid ester and following one or more materials：Phosphatide, sucrose fat
Acid esters, polyglyceryl fatty acid ester, list, diglycerine fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60,
Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~
5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.
Preferably, the emulsifying agent includes lactic acid fatty glyceride and following one or more materials：Phosphatide, Sucrose Fatty Acid Ester
Fat acid esters, polyglyceryl fatty acid ester, list, diglycerine fatty acid ester, methyl glycol fatty acid ester, polysorbas20, polysorbate40, polysorbate60,
Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17；Wherein the content of emulsifying agent using weight ratio meter as 0.06%~
5%, the content of preferred emulsifier is using weight ratio meter as 0.3%~3%.
Specifically, it is preferred that the content of emulsifying agent of the present invention using weight ratio meter as 0.05%, 0.06%, 0.07%, 0.08%,
0.09%、0.1%、0.2%、0.3%、0.4%、0.5%、0.6%、0.7%、0.8%、0.9%、1%、1.1%、1.2%、1.3%、1.4%、
1.5%、1.5%、1.6%、1.7%、1.8%、1.9%、2%、2.1%、2.2%、2.3%、2.4%、2.5%、2.6%、2.7%、2.8%、
2.9%、3%、3.1%、3.2%、3.3%、3.4%、3.5%、3.6%、3.7%、3.8%、3.9%、4%、4.1%、4.2%、4.3%、4.4%、
4.5%、4.6%、4.7%、4.8%、4.9%、5%、5.1%、5.2%、5.3%、5.4%、5.5%、5.6%、5.7%、5.8%、5.9%、6%、
6.1%、6.2%、6.3%、6.4%、6.5%、6.6%、6.7%、6.8%、6.9%、7%、7.1%、7.2%、7.3%、7.4%、7.5%、
7.6%th, 7.7%, 7.8%, 7.9% or 8%.
Preferably, the lecithin in phosphatide of the present invention, preferably phosphatide（That is phosphatidyl choline）Content be more than 40%,
It is preferred that the content of the lecithin in the phosphatide is more than 50%；It is preferred that the content of the lecithin in the phosphatide is more than 60%.
Specifically, it is preferred that the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill
Oil.
Further, in the hydrophilic lipid composite of the present invention, can also containing taste improve composition, such as
Including but not limited to flavorant or flavoring essence, sweetener, such as steviol glycoside, glycyrrhizin, Sucralose, etc..
Hydrophily lipid composite of the present invention, there is outstanding hydrophily, it shakes in water fluid through shaking,
Homogeneous, stable emulsion can quickly be formed；
Or hydrophily lipid composite of the present invention, there is outstanding hydrophily, it is in the water fluid containing ethanol
In, shaken through shaking, can quickly form homogeneous, stable emulsion.
Water fluid of the present invention, including water, water content are more than 60% liquid, or the aqueous solution containing ethanol.
Rolling of the present invention of shaking, refers to the operating method by vibrating, rocking or rock, mixture is produced in a reservoir
Quick flowing, rolling or/and the motion of collision impact, mixture is set to produce rolling of shaking with hand including the use of person, or, using machine
Operation makes mixture produce rolling of shaking, for example with the operation of manipulator.
Liquid aliphatic of the present invention, including the aliphatic acid or grease of liquid are presented at normal temperatures and pressures, preferably include
Saturated or undersaturated aliphatic acid, saturation or undersaturated grease, the triglycerides of saturated or undersaturated aliphatic acid, saturation or
The diglyceride of undersaturated aliphatic acid, such as including but not limited to oleic acid, linoleic acid, alpha-linolenic acid, gamma-Linolenic acid, middle chain
Triglycerides, diglyceride, middle long chain fatty acids, etc..
Further, invention further provides contain hydrophily lipid composite of the present invention and water fluid
Packaging compositions, the packaging compositions method that is deployed into emulsion.
A kind of packaging compositions, including hydrophily lipid composite is independently packed and combined one with water fluid
Rise, the hydrophily lipid composite contains liquid aliphatic and emulsifying agent, and wherein liquid aliphatic is selected from following one or more things
Matter：Medium chain triglyceride, alpha-linolenic acid, gamma-Linolenic acid, diglyceride, oleic acid, linoleic acid, middle long chain fatty acids, liquid aliphatic
Content in hydrophily lipid composite is more than 45% with weight ratio meter；
Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol ester
Fat acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, department
Disk 40, sorbester p18, sorbester p38, sorbester p17, content of the emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.05%~
8%；
The water fluid, 60% liquid, or the aqueous solution containing ethanol are more than selected from water, water content；
The weight ratio of the water fluid and hydrophily lipid composite is more than 3:1；
The volume summation of the water fluid and hydrophily lipid composite is not more than the container capacity of receiving water fluid
98%。
Above-mentioned packaging compositions, further contain liposoluble substance B, the liposoluble in the hydrophily lipid composite
Property substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin A, dimension life
Plain D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, phytostanol
Ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein contents of the liposoluble substance B in hydrophily lipid composite are with weight
Amount ratio is calculated as 0.01%~30%.
Specifically, various combinations provided by the invention, the hydrophily fat of specific composition, proportioning, preparation method, concocting method
Based composition, the hydrophily lipid composite suitable for above-mentioned packaging compositions.
The packaging compositions, including hydrophily lipid composite of the present invention is independently wrapped with water fluid
Fill and combine, such as form combination in same packing box or packaging bag, such as, by the only of lipid composite
The form that vertical packaging fixed or packed external member by pasting fixed, label with the independent packaging of water fluid combines the shape together with
Into packaging compositions, " form for fixing or packing external member by pasting fixed, label is combined ", refer to pass through glue
The mode such as band or sticky glue combines the independent packaging of lipid composite and the independent packaging of water fluid；Or use fat
The Product labelling of based composition, the Product labelling of water fluid, by active forces such as the binding of label, parcel, windings, by lipid
The independent packaging of composition and the independent packaging of water fluid are combined；Or by the independent packaging of lipid composite and water
The independent packaging of base fluid body is arranged to pack the mode of external member, combines, for example, setting one on the container of water fluid
Individual groove, by the packing material card of lipid composite in a groove, formed packaging external member, or by lipid composite it is independent sealed in
In the chamber of the The lid component of container, water fluid is sealed in container, and the The lid component of container is arranged on to the opening of container
Place seals to container so that lipid composite is each independent sealed with water fluid, when in use, by the The lid component of container
Open, discharge the lipid composite in The lid component, mixed with the water fluid in container, further, shaken by shaking to be formed
Homogeneous emulsion；For example, the The lid component of described container, refers to be similar to disclosed in international publication WO2007/129126
Technical scheme.
Or in the packaging compositions, including by hydrophily lipid composite independent packaging of the present invention, and with
Allotment bottle is present in same packaging housing unit simultaneously, and the allotment bottle is the empty bottle with lid, preferably allocates on bottle indicating
The graduation mark of the amount in need for adding water fluid, in use, only need the packing material opening of hydrophily lipid composite, will
Hydrophily lipid composite is poured into allotment bottle, adds water fluid, to facilitate allotment, rolling of shaking, makes aliphatic acid composition very
Homogeneous emulsion is formed in water fluid well and is used, is also convenient for the hydrophily lipid group that user decides addition in its sole discretion
The amount of the amount of compound and the water fluid added.
Or special situation is, packaging compositions of the present invention, in the packaging compositions, can not adjust
With bottle, but it is labeled with the label of the packing material of hydrophily lipid composite and passes through the lipid composite with water fluid
Mix in a reservoir and by mixed liquor shake and shake and obtain the content information of emulsion, and the bag of lipid composite of the present invention
Fill the technology contents of composition, i.e. hydrophily lipid composite, and be labeled with its Product labelling and combine hydrophily lipid
Thing shakes with the mixed merga pass of water fluid to shake and obtains the content of emulsion.
Combination, storage of the above-mentioned packaging compositions more convenient for lipid composite and water fluid, are more beneficial for lipid group
The allotment of compound and water fluid uses, the method that described hydrophily lipid composite is deployed into emulsion with water fluid,
Including：Hydrophily lipid composite is poured into the container for accommodating water fluid, wherein water fluid and hydrophily lipid group
The weight ratio of compound is more than 3:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than the 98% of container capacity,
The lid of container is tightened, bottle will be allocated in the frequency of shaking at least 1 time of being shaken in 1 second with hand or manipulator, container rolling of shaking is not surpassed
Spend 10 seconds, container shake rolling when, the distance of each displacement of container is not less than 10 centimetres, and makes the residue of mixed liquor to container empty
Between move and form emulsion, preferably container shake rolling when, make the mixed liquor move to the remaining space of container and impact to allocate bottle
Lid；
Wherein hydrophily lipid composite includes any one hydrophily lipid composite of the present invention；
The water fluid, 60% liquid, or the aqueous solution containing ethanol are more than selected from water, water content；
The container of the water fluid, selected from vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, gold with cover
Belong to container, and the volume of container is not more than 3 liters.
Specifically, water fluid of the present invention includes but is not limited to the aqueous solution of water, carbohydrate（It is such as single
Sugar, disaccharide, oligosaccharide, polysaccharide etc.）, dietary fiber the aqueous solution（Such as inulin, FOS, polydextrose）, dietary fiber
Aqueous suspension, the aqueous solution of amino acid, the aqueous solution of vitamin, the aqueous solution of electrolyte（As potassium chloride, magnesium sulfate it is water-soluble
Liquid）, probiotics the aqueous solution or suspension, animal emulsion（Such as milk, goat milk, mare's milk）, animal albumen powder aqueous emulsion（Such as
Milk powder, the aqueous emulsion of goat milk powder, the aqueous emulsion of refined lactoprotein powder）, plant protein powder aqueous emulsion（Soybean protein
The aqueous emulsion of powder, peanut protein powder）, liquid juice, liquid vegetable juice, the aqueous extract of plant, plant extracts it is water-soluble
Liquid or water suspension（Such as the water suspension of the aqueous solution of tealeaves or coffee, tealeaves or coffee）, homogenate diet, ethanol water（Such as drink
With wine, beer, cocktail）, etc..
Preferably, water fluid of the present invention is selected from the aqueous solution of following one or more materials：Sucrose, glucose,
It is fructose, maltose, chitosan oligosaccharide, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, sweet
Propylhomoserin, aspartic acid, asparagine, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B,
L-cn, folic acid, nicotinic acid, choline, inositol；Or, it is preferred that water fluid of the present invention is selected from animal emulsion, animal
The aqueous emulsion of albumen powder or the aqueous emulsion of plant protein powder.
Above-mentioned water fluid, on the one hand, water-soluble or protide nutriment is provide not only, it is and provided by the invention
Hydrophily lipid composite has the pharmacological action that nutrition cooperates with, and on the other hand, above-mentioned water fluid is more beneficial for and hydrophily
Lipid composite is quick under rolling effect of shaking to form emulsion, and keeps good, is not easy the stability of emulsion that is layered.
Emulsion is a complicated, thermodynamic stable system, especially different types of fats or fat-soluble ingredient, by
Different in the fat-water distribution and combination energy state of each component, the stability for whole system is vital, multi-component fat
Newborn system, it is easy to the wild effects such as fat floating, flocculation or layering, production method and technique occur, decide emulsion
The form and size of middle fat globule, and the microphenomenons such as aggregation whether can occur, so as to influence the fat of emulsion in macroscopic aspect
Fat floating, flocculation or layering etc. are unstable, in addition, also contributing to emulsion digesting and assimilating and utilizing to human body.
However, disadvantageously, after emulsifying agent mixes with vegetable oil, in the environment of normal temperature or slightly below normal temperature, it is long placed in meeting
Become cloudy grease, such as phosphatide can separate out precipitation, have a strong impact on the quality of product.Inventor occurs such a existing by research
As the reason for be due to emulsifying agent be not easy to vegetable oil be blended, such as phosphatide freezing point be higher than vegetable oil freezing point, make
The phosphatide that can not be blended with vegetable oil is obtained, precipitation can be separated out at a temperature of less than its freezing point, so as to cause grease to become cloudy,
Or phosphatide can separate out precipitation.
Therefore, the preparation method of hydrophily lipid composite of the present invention is vital that inventor has found, by adding
Heat, mixed at high speed make emulsifying agent and vegetable oil generation blending, state of dissolving each other, and are allowed to be evenly distributed, and further quickly, precisely drop
Temperature, or form the miscible composition of oil-gas, makes emulsifier molecules in rapid cooling, in emulsified dose point of high dispersion state
Son can form the colloidal solution of small molecule crystallite state, reach the stable mixture of emulsifying agent and vegetable oil.
Further, the present invention provides a kind of preparation method of above-mentioned hydrophily lipid composite, and it includes：
(1) dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed
Splitting or integrating dissipates uniform；
(2) liquid prepared in (1) is placed in emulsion tank, heating makes fluid temperature be more than 45 DEG C, big in speed of agitator
Under conditions of 500r/min, speed of agitator is preferable over more than under conditions of 1000r/min, is stirred 3~25min of operation,
Then rapidly by liquid cooling to less than 25 DEG C in 3~5min, stop stirring, stand；Or the liquid that will be prepared in (1)
Body is placed in emulsion tank, and heating makes fluid temperature be more than 45 DEG C, and the homogeneous that pressure is 20~58MPa is carried out in homogenizer,
Then rapidly by liquid cooling to less than 25 DEG C in 3~5min, stirring is stopped；
(3) it is filling：Oily liquids is subjected to vacuum outgas, it is filling, sealing, packaging, examine, produce hydrophily lipid group of the present invention
Compound.
Hydrophily lipid composite prepared by the above method of the present invention, generally in the faint yellow clear oil to buff
Thing.Further, hydrophily lipid composite and water fluid are shaken to be deployed into emulsion by shaking.
For hydrophily lipid composite of the present invention, compatibility and dispersiveness with water fluid are most important
, the preparation method of composition miscible using oil-gas of the invention, produced altogether in liquid aliphatic for emulsifying agent
It is mixed, and all there is good raising to act on for the hydrophily of lipid composite.Further, the invention provides hydrophily
Second of preparation method of lipid composite, it includes：
(1) dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed
Splitting or integrating dissipates uniform；
(2) liquid prepared in (1) is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps emulsion tank
In pressure be more than 1.3 atmospheric pressure, and be stirred 3~25min of operation under conditions of speed of agitator is more than 300r/min, make
The oily liquids of the foam type rich in nitrogen of nontransparent shape is presented in oily liquids, stops stirring；
(3) it is filling：Will（2）The oily liquids of middle preparation is filling in container, optionally container is carried out to be filled with nitrogen, and make appearance
Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces hydrophily lipid composite.
Hydrophily lipid composite prepared by the above method of the present invention, is the foam type grease thing containing nitrogen, is presented non-
Transparence, estimate the visible wherein bubble containing fine uniform, or foam-like is presented in the grease of liquid.Further, will
Hydrophily lipid composite is shaken to be deployed into emulsion with water fluid by shaking.
Further, the present invention provides the preparation method of the hydrophily lipid composite described in the third, and it includes：
（1）Dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, it is stand-by；
（2）Liquid aliphatic and liposoluble substance are mixed, stirring, its mixing is uniformly dispersed, obtain the mixing of liposoluble substance
Thing；
（3）The premixing of emulsifying agent：Take 3~7 times of emulsifying agent and emulsifying agent weight（2）The mixing of the liposoluble substance of middle preparation
Thing, it is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure,
And stirred under conditions of speed of agitator is more than 300r/min, make oily liquids that the foam type rich in nitrogen of nontransparent shape be presented
Oily liquids, or grease present foam-like, stop stirring；
（4）The pre-mixed material of the emulsifying agent prepared in (3) is placed in emulsion tank, adds the mixed of remaining liposoluble substance
Compound, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure, and in speed of agitator
More than being stirred under conditions of 300r/min, make oily liquids that the foam type grease thing rich in nitrogen of nontransparent shape be presented, stop
Stirring；
(5) it is filling：Will（4）The oily liquids of middle preparation is filling in container, optionally container is carried out being filled with nitrogen and makes appearance
Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces hydrophily lipid composite.Further, will
Hydrophily lipid composite is shaken to be deployed into emulsion with water fluid by shaking.
Another aspect, the present invention provides one kind and contains emulsifying agent and liquid aliphatic hydrophily lipid composite, and it is special
Sign is to be made of the first above-mentioned preparation method, second of preparation method or the third preparation method.
Further, the present invention provides a kind of hydrophily lipid composite of foam type, contains emulsification of the present invention
Agent, liposoluble substance A, liposoluble substance B and nitrogen, the emulsifying agent are selected from following one or more materials：Phosphatide, Sucrose Fatty Acid Ester
Fat acid esters, list, diglycerine fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, tween
20th, the content of polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent with
Weight ratio meter is 0.05%~8%；The liposoluble substance A is selected from following one or more materials：Oleic acid, linoleic acid, leukotrienes,
Medium chain triglyceride, diglyceride, middle long chain fatty acids, wherein liposoluble substance A content are more than 45% with weight ratio meter；Institute
State liposoluble substance B and be selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E, vitamin
A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester, plant steroid
Alkanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content are excellent using weight ratio meter as 0~30%
Liposoluble substance B content is selected using weight ratio meter as 0.01%~30%；The leukotrienes includes alpha-linolenic acid or gamma-Linolenic acid,
The middle long chain fatty acids include medium chain fatty acid or long chain fatty acids, and the emulsifying agent also includes its various model, specification, gathered
Right, esterification degree, mono-/bis-ester, or its monomer component for including, the content of lecithin is more than 40% in the phosphatide；It is it is preferred that described
Emulsifying agent is selected from phosphatide and following one or more materials：Sucrose fatty ester, list, diglycerine fatty acid ester, polyglycereol fat
Acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, sapn
40th, sorbester p18, sorbester p38, sorbester p17；The wherein content of emulsifying agent is using weight ratio meter as 0.1%~4%, the content of preferred emulsifier
Using weight ratio meter as 0.2%~3%；Its preparation method uses above-mentioned second of preparation method or the third preparation method.
Inventor surprisingly has found, hydrophily lipid composite provided by the invention, in water fluid, is shaken through shaking, can
Emulsion is quickly formed, for example, by the operation for rolling of shaking, by hydrophily lipid composite of the present invention and water fluid in closing
Mixed in container, such as in the beverage bottle using bottle cap closing, hydrophily lipid composite and water fluid are in a reservoir
Cumulative volume is not higher than in 98% volume space of container total capacity, by way of hand shakes rolling, rolling 1~3 time of acutely shaking, this
Invention lipid composite can form emulsion at once with water fluid, and the emulsion stands 5min, or even more than 10min, still
Homogeneous, stable emulsion is kept, consumer or patient's allotment is very easy to and eats；In addition, the hydrophily lipid group
Compound and water fluid are allocated to form emulsion after, even if after standing and being layered through the long period, through slight wobble, can still divide
Dissipate for emulsion, can't influence to drink or eat.Inventor is shaking lipid composite provided by the invention and water fluid
Under rolling effect, moment forms the process or technology of emulsion, is referred to as " oil-water wink mixes ".
It should be noted that whether observation emulsion is layered, it is so that the liquid level that lipid material swims in water fluid occurs
On, and it is standard to form lipid material clearly released state occur with water fluid；In addition, in observation, it shall be noted that area
Bubble present on the liquid level of other emulsion or foam and the essential distinction of emulsion layering；Generally, hydrophily lipid of the present invention
Composition is forming emulsion with water fluid through cross to shake rolling, can all produce the bubble or foam of emulsion, and caused
Bubble or floatation of foam are on the liquid level of emulsion, but the bubble of this floating or foam are not that emulsion is layered, this
One phenomenon is it is noted that difference.
Further, the invention provides the user containing emulsifying agent and liquid aliphatic hydrophily lipid composite
Method, it includes adding hydrophily lipid composite in water fluid, is shaken through shaking, form it into emulsion and further use,
For example, it is preferable to the application method as the product for drinking the nutrition treatments such as ready-mixed oil, drinkable healthy oil；
Or further, the invention provides the application method of described hydrophily lipid composite, and it is included the present invention
After described hydrophily lipid composite mixes with water fluid, shaken in the container of closing through shaking, become emulsion；
Wherein, the water fluid includes the liquid of water, water content more than 60%, or the aqueous solution containing ethanol；It is described to shake
Shake, the frequency of at least 1 time rolling of shaking preferably was carried out in 1 second, and the time for rolling of shaking is no less than 1 second.
Further, the invention provides contain emulsifying agent and liquid aliphatic hydrophily lipid composite and water fluid
Mixing preparation method, including will carry out after lipid composite and water fluid mixture shaking rolling and form emulsion, it is described
Water fluid includes the liquid of water, water content more than 60%, or the aqueous solution containing ethanol.
On the other hand, it is provided by the invention containing emulsifying agent and liquid aliphatic hydrophily lipid composite, have quick
Water emulsification performance, preferably by the hydrophilic lipid composite of the present invention and be deployed into emulsion using allotment bottle, particularly, with
Following method of the method as the fast deployment of hydrophily lipid composite and water fluid into aqueous emulsion：By hydrophily lipid
Composition is poured into allotment bottle with water fluid, and the weight ratio of wherein water fluid and hydrophily lipid composite is more than 3:1, it is excellent
The weight ratio of water fluid and hydrophilic lipid composite is selected to be more than 10:1, make hydrophily lipid composite and water fluid
Cumulative volume is no more than the 98% of allotment bottle capacity, tightens the lid of allotment bottle, is shaken with hand or manipulator by bottle is allocated in 1 second
The frequency of at least 1 time is shaken, allotment bottle is shaken rolling no more than 10 seconds, allotment bottle is shaken rolling no more than 5 seconds, allotment bottle shakes
During rolling, the distance of the allotment each displacement of bottle is not less than 10 centimetres, and moves the remaining space of mixed liquor to allotment bottle, preferably
Move the remaining space of mixed liquor to allotment bottle and impact the lid of allotment bottle, you can form homogeneous emulsion, the milkiness
Liquid stands 5min and keeps homogeneous milkiness liquid status at room temperature, is not layered；The allotment bottle, including vial with cover,
Plastic bottle with cover, aluminium with cover-modeling carton, canister with cover, for example, macromolecule PET bottle, high-density polyethylene bottle
Bottle, etc.；It is preferred that the volume of allotment bottle is not more than 3 liters, the volume for most preferably allocating bottle is not more than 3 liters, preferably allocates the appearance of bottle
Product for 2.5 liters, 1.5 liters, 1 liter, 0.9 liter, 0.8 liter, 0.7 liter, 0.6 liter, 0.5 liter, 0.45 liter, 0.4 liter, 0.3 liter, 0.2 liter,
0.15 liter, 0.1 liter, 0.09 liter, 0.08 liter, 0.07 liter, 0.06 liter, 0.05 liter or 0.04 liter, etc.；The water fluid includes
Water, water content are more than 60% liquid, or the aqueous solution containing ethanol.
The present invention contains emulsifying agent and liquid aliphatic hydrophily lipid composite, has unexpected quick water and milk
Change performance, be used for bringing great convenience and novel sense.
Hydrophily lipid composite of the present invention by shake shake, can rapidly or moment in water disperse, have soon
The hydrophilic characteristic of speed.Further, the skill the invention provides described hydrophily lipid composite fast deployment into emulsion
Art scheme.A kind of hydrophily lipid composite containing emulsifying agent, liposoluble substance A and liposoluble substance B, the emulsifying agent choosing
From following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglyceryl fatty acid ester, the third two
Alcohol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18,
The content of sorbester p38, sorbester p17, wherein emulsifying agent is using weight ratio meter as 0.05%~8%, and the content of preferred emulsifier is with weight ratio
It is calculated as 0.1%~6%；The liposoluble substance A is selected from following one or more materials：Oleic acid, linoleic acid, alpha-linolenic acid, γ-Asia
Numb acid, medium chain triglyceride, diglyceride, middle long chain fatty acids, wherein liposoluble substance A content are more than with weight ratio meter
45%；The liposoluble substance B is selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E,
Vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester,
Plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B content using weight ratio meter as 0~
30%, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, emulsion can be formed within 5 seconds, and
And the emulsion standing at least 1min formed, homogeneous milkiness liquid status can be kept, are not layered, wherein water fluid and parent
The weight ratio of water-based lipid composite is more than 3:1, the weight ratio of preferably water fluid and hydrophilic lipid composite is more than
10:1；
The water fluid, including：Water, water content are more than 60% liquid, or the aqueous solution containing ethanol；
The rolling of shaking, refers to the operating method by vibrating, rocking or rock, and mixture is produced motion, rolling in a reservoir
Or/and the motion of collision impact, mixture is produced rolling of shaking with hand including the use of person, or, mixture is made using machine operation
Generation is shaken rolling, for example with the operation of manipulator.
The speed of the rolling of shaking, the frequency of at least 1 time rolling of shaking preferably was carried out in 1 second；
The middle long chain fatty acids include medium chain fatty acid or long chain fatty acids；
Preferably, the content of the liposoluble substance B is using weight ratio meter as 0.01%~30%；
Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 4 seconds
Turbid；
Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 3 seconds
Turbid；
Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 2 seconds
Turbid；
Preferably, it is characterised in that hydrophily lipid composite and water fluid are shaken by shaking, breast can be formed within 1 second
Turbid.
Hydrophily lipid composite of the present invention, belongs to lard type composition, for easy to use, more preferable absorption,
Hydrophily lipid composite of the present invention is formed into emulsion in water base liquid to be very important.For example, this is sent out
The bright healthy food or beverage mate for providing described hydrophily lipid composite as various water base liquid foods, preferably
As homogenate diet, milk, beverage, the aqueous solution, fruit juice, coffee, liquid food, such as gruel, rice paste, batter, reconstituted food, wheat is such as reconstituted
Piece, soaking milk powder, reconstitute coffee, reconstitute solid beverage, etc.；Drink ready-mixed oil preferably as what is allocated available for water, can drink
Use healthy oil；More preferably emulsion is deployed into using water fluid to use.
Present invention also offers described hydrophily lipid composite be applied to medicine, special medicine purposes formula food,
Health food, nutraceutical or cosmetics, etc., on the one hand, contain in the hydrophily lipid composite to health and
The unrighted acid and fats health ingredients of rehabilitation effect, are particularly suitable for use in and prepare medicine, special medicine purposes is matched somebody with somebody
Square food, health food, nutraceutical or cosmetics, on the other hand, hydrophily lipid composite of the invention belong to liquid,
Grease type solvent can be used as, fat-soluble medicine is dissolved and can further be allocated, is dispersed in shape in water fluid
Use, in favor of the oral of fat-soluble medicine, absorption and utilize, for example, fat-soluble medicine includes A Defu into emulsion
Wei ester, tenofovir disoproxil, lutein ester, Co-Q10, etc..In addition, when being used for cosmetics, as moisturizing essential oil, skin care essence
Oil, Hair-conditioning essential oil, or water is dissolved in as face, the moisturizing of skin, repairing cosmetics, and skin-nourishing oil breast, etc., use
In the nursing to skin and beauty, etc..Particularly, hydrophily lipid composite of the present invention, as drinking ready-mixed oil,
The health such as drinkable healthy oil, health care, the product of nutrition treatment.Particularly, the even of special medicine purposes formula food is being prepared
Starch the application in meals.
Therefore, present invention also offers containing the emulsifying agent and liquid aliphatic hydrophily lipid composite by with water
Base fluid body mix, and further through shake shake and be deployed into emulsion, prepare or allocate medicine, special medicine purposes formula food
Application in terms of product, health food, nutraceutical or cosmetics, especially preparing or allocating the medicine being orally ingested immediately, spy
Application in different medical usage formula food, health food, nutraceutical, or in the cosmetics prepared or allotment uses immediately
In application, greatly facilitate user instant allotment, immediately use.
Present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid
Close, through shake shake and be prepared into the application in emulsion.
Present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid
Close, and further through shake shake and be deployed into emulsion, in the homogenate diet for preparing special medicine purposes formula food food should
With.
Present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid
Close, through shake shake and be prepared into emulsion, and be further used for canteen make in application, with emulsion replace canteen making in
Water be applied to canteen make in, including but not limited to make steaming savor food, boil savor food, modulation wheaten foods, mix food it is all kinds of
Application in food or reconstituted food beverage.
On the one hand, hydrophily lipid composite of the present invention, can provide beneficial for health and disease treatment
Unrighted acid, such as nervonic acid, alpha-linolenic acid, gamma-Linolenic acid, DHA, EPA, arachidonic acid, etc., and fat-soluble
Medicine or nutriment, such as vitamin E, medium chain triglyceride, phosphatide, vitamin A, vitamin D, lutein ester, Co-Q10,
Etc.；On the other hand, emulsifying agent and liposoluble substance of the present invention have good pharmacology synergy, for health, especially
It has good synergy in oral supplementation phosphatide, unrighted acid and fat-soluble medicine etc..Therefore, more enter
One step, present invention also offers containing emulsifying agent and liquid aliphatic hydrophily lipid composite by being mixed with water fluid
Close, through shake shake and be prepared into the emulsion for being available for orally drinking, prepare preventing and treating cardiovascular and cerebrovascular disease medicine or Special food
The application of aspect；Application in terms of preparing nutrition or protecting the medicine or Special food of cranial nerve；Moved back preparing preventing and treating nerve
Application in the medicine of row disease；The risk caused by preparation reduction generation myocardial infarction, cerebral apoplexy or angiocardiopathy
Applied in medicine；Improve myocardial ischemia and improvement cerebral ischemia, protection heart and brain cell, reducing blood lipid, preventing and treating cardiovascular and cerebrovascular disease preparing
Application in sick, protection cardiovascular and cerebrovascular medicine；Application in terms of the medicine or Special food for the treatment of fatty liver is prepared；Making
Application in terms of the medicine or Special food of standby fat-reducing；Application in terms of antifatigue medicine or Special food is prepared；Making
Application in terms of the standby medicine or Special food that unrighted acid is provided；Or provide fat-soluble medicine or spy preparing
Application in terms of different food.
Hydrophily lipid composite of the present invention, it can also be used to during canteen makes, made in any need of water
Or in the various canteens of allotment, can be with the emulsion that hydrophily lipid composite of the present invention and water are deployed into come generation
For application of the water in canteen making, the canteen thus made, not only supplemented with aliphatic acid and liquid aliphatic needed by human, and
And produced canteen, the suitable salted cake fried in sesame oil taste of also light concentrated phase, be advantageous to improve appetite, it is often more important that, the mistake that canteen makes
Journey, for consumers, on the one hand, be a kind of enjoyment, especially pass through oil-based materials and water-based material one or two second
Shake rolling process, moment is changed into emulsion, drastically increases the desire drunk or fed of consumer, this from allotment diet
Process, caused psychological desire contribute to the intake of the oil-based materials of health-nutrition of the present invention；On the other hand, by parent of the invention
The process of aqueous lipid composition and water allotment, it is that a kind of tune canteen producer starts, beaten one's brains and the process with eye, especially will
Oil-based materials and water-based material are changed into emulsion, drastically increase consumer's by the rolling process of shaking of one or two second, moment
The desire drunk or fed, it is this to contribute to health-nutrition of the present invention from the process for allocating diet, caused psychological desire
The intake of oil-based materials；In addition, this rolling of shaking（Vibrate and rock）Process can discharge pressure, what this process was brought is a kind of
Pleasant mood, optimizes diet mood, and this state being in a cheerful frame of mind contributes to healthy diet, and it is strong to not only facilitate the present invention
The effect of the oil-based materials of health nutrition is played, and can more improve the amount to beverage or homogenate diet, and drink rate is abandoned in reduction, is reduced and is wasted
And pollution.
Hydrophily lipid composite provided by the invention, the product preparing mode that oil-water quickly mutually melts is realized, there is weight
Big meaning.For beverage or homogenate diet, oil-based materials are independently packed with water-based material, and by both independent packaging groups
It is combined, both is quickly mixed by way of shaking and shaking allotment when in use and form emulsion, this method causes
Oil-based materials independently preserve with water-based material and significantly improve respective stability, without adding emulsion stabilizing agent, avoid
Unrighted acid is degraded, and is greatly improved the stability of product, be ensure that quality, maintains good flavor and mouth
Sense, also extends shelf life or shelf-life, is advantageous to the quality assurance and circulation of commodity.
Further healthy meaning is hydrophily lipid composite provided by the invention, can not only to bring consumer
More health fat, such as medium chain triglyceride, omega-fatty acid, ω -6 aliphatic acid, phosphatide, arachidonic acid, vitamin
E, the health such as vitamin A, vitamin D, CLA, phytosterol, nutrition, the material of disease prevention and cure class, such as protect the heart
The cerebrovascular, improve intelligence, trophic nerve；And consumer is easier, more easily with beverage, homogenate diet, common canteen
Mode obtain these materials highly beneficial to health, disease prevention and cure.
It is contemplated that hydrophily lipid composite provided by the invention, is advantageous to improve the existing eating habit of people,
The canteen for being even advantageous to improve the mankind makes custom and canteen collocation theory.
It should be understood that, oral preparation needs that by the absorption of intestines and stomach blood of human body could be entered to reach physiology work
With, the quality of oral absorption, the therapeutic effect of medicine is directly affected.According to the concept of pharmacy, bioavilability
(Bioavailability) refer to preparation to be rapidly absorbed into sanguimotor producing level and utilize speed.
It is fast in water base liquid containing emulsifying agent, liposoluble substance compared to the preparation of other non-emulsified liquid types, the present invention
Speed forms emulsion, has excellent water-oily dissolubility, is being absorbed for the oral formulations using liposoluble substance as active ingredient
In terms of sanguimotor degree and speed, there is significant facilitation and meaning, this biology for liposoluble substance
The raising of availability is significant.The absorption process that preparation enters after stomach and intestine, in two stages, i.e., scattered and gastrointestinal wall are inhaled
Two stages are received, are scatter firstly the need of in gastric juice or intestinal juice, then contacts again and is attached to gastrointestinal wall and absorbed and entered
Enter blood, the two stages can all influence absorbing and being good for for the liposoluble substance of unrighted acid and other healthy functions
Kang Zuoyong performance, liposoluble substance is prepared as the good emulsion of water dispersible, the dissolution of liposoluble substance and scattered
Speed is dramatically speeded up, and is substantially increased degree and rate of dispersion that it disperses in gastric juice or intestinal juice, is made liposoluble substance and stomach
The contact of intestinal wall is more abundant, and the active ingredient for being attached to Gastrointestinal Wall Absorption and entering blood is also more abundant, and this is for fat-soluble
The raising of the bioavilability of material is significant.For example, nervonic acid, DHA, EPA, phosphatidylserine, medium chain triglyceride
Three esters, alpha-linolenic acid, gamma-Linolenic acid etc. are deployed into milkiness by hydrophily lipid composite provided by the invention and water fluid
Liquid is drunk, its bioavilability（Bioavailability) it is obviously improved, there is highly significant effect.
Hydrophily lipid composite and its concocting method of the present invention, solve the shortcomings of prior art, have following
Advantage：1st, grease-like composition, not aqueous, stability is good；2nd, there is outstanding hydrophily, can be mixed with water and disperse to form milkiness
Liquid, be advantageous to edible and easy to operation；3rd, allotment is convenient, fast, by rolling of shaking in a reservoir, can be formed in 1~5 second homogeneous
Emulsion, allocate or make the mood for bringing pleasure to diet, help to discharge pressure and healthy diet, optimize diet feelings
Thread；4th, the bioavilability of functional fatty acid or liposoluble substance is improved；5th, the emulsion formed has preferable stability,
More than 5min is stood, homogeneous, stable emulsion can be kept；6th, the emulsion formed is after being long placed in and being layered, through slight
Rock, can still form homogeneous emulsion, be advantageous to user and drink or be orally ingested by phased manner.
For embodiment in the implementation process of the present invention, those of ordinary skill in the art are not departing from the present invention's
Caused various embodiments and modification are obvious and are easy to perform on the basis of scope and spirits.It is logical
Cross the following examples to be further elaborated with come application to the present invention etc., it is not intended that limit of the embodiment to the present invention
System.
Embodiment 1, hydrophilic lipid composite, its preparation and concocting method, it is applied in combination.
Hydrophilic lipid composite, recipe quantity by weight percentage, contain respectively：
Wherein, the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil.
Its preparation method one, including：
(1) dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed
Splitting or integrating dissipate it is uniform, or, first by other liposoluble substances, such as nervonic acid, DHA, arachidonic acid, phytosterin ester or phosphatide
Acyl serine adds liquid aliphatic and it is dissolved completely in liquid aliphatic, adds emulsifying agent, is stirred, is uniformly dispersed；
(2) liquid prepared in (1) is placed in emulsion tank, heating makes fluid temperature be more than 45 DEG C, big in speed of agitator
Under conditions of 500r/min, be stirred 3~25min of operation, then in 3~5min rapidly by liquid cooling to 25 DEG C with
Under, stop stirring, stand；Or the liquid prepared in (1) is placed in emulsion tank, heating make fluid temperature for 45 DEG C with
On, in homogenizer carry out pressure be 20~58MPa homogeneous, then in 3~5min rapidly by liquid cooling to 25 DEG C with
Under, stop stirring；
(3) it is filling：Oily liquids is subjected to vacuum outgas, it is filling, sealing, packaging, examine, produce.
Or its preparation method two, including：
(1) dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed
Splitting or integrating dissipate it is uniform, or, first by other liposoluble substances, such as nervonic acid, DHA, arachidonic acid, phytosterin ester or phosphatide
Acyl serine adds liquid aliphatic and it is dissolved completely in liquid aliphatic, adds emulsifying agent, is stirred, is uniformly dispersed；
(2) liquid prepared in (1) is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps emulsion tank
In pressure be more than 1.3 atmospheric pressure, and be stirred 3~25min of operation under conditions of speed of agitator is more than 300r/min, make
The foam type grease thing rich in nitrogen of nontransparent shape is presented in oily liquids, stops stirring；
(3) it is filling：Will（2）The oily liquids of middle preparation is filling in container, further container is carried out to be filled with nitrogen, and make appearance
Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces.
Or its preparation method three, including：
（1）Dispensing：Emulsifying agent, liquid aliphatic, other liposoluble substances are weighed by formula, it is stand-by；
（2）Liquid aliphatic and liposoluble substance are mixed, stirring, its mixing is uniformly dispersed, obtain the mixing of liposoluble substance
Thing, or, first other liposoluble substances, such as nervonic acid, DHA, arachidonic acid, phytosterin ester or phosphatidylserine are added
Enter liquid aliphatic and it is dissolved completely in liquid aliphatic, be stirred, be uniformly dispersed；
（3）The premixing of emulsifying agent：Take 3~7 times of emulsifying agent and emulsifying agent weight（2）The mixing of the liposoluble substance of middle preparation
Thing, it is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure,
And stirred under conditions of speed of agitator is more than 300r/min, make oily liquids that the foam type rich in nitrogen of nontransparent shape be presented
Foam-like is presented in grease thing, or grease, stops stirring；
（4）The pre-mixed material of the emulsifying agent prepared in (3) is placed in emulsion tank, adds the mixed of remaining liposoluble substance
Compound, nitrogen is continually fed into oily liquids or keeps the pressure in emulsion tank to be more than 1.3 atmospheric pressure, and in speed of agitator
More than being stirred under conditions of 300r/min, make oily liquids that the foam type grease thing rich in nitrogen of nontransparent shape be presented, stop
Stirring；
(5) it is filling：Will（4）The oily liquids of middle preparation is filling in container, further container is carried out being filled with nitrogen and makes appearance
Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces.
Fast deployment performance：The hydrophily lipid composite that any one in the present embodiment matches is poured into water fluid
Allocate in bottle, the weight ratio of wherein water fluid and hydrophilic lipid composite is more than 10:1, make hydrophily lipid composite
It is no more than the 98% of allotment bottle capacity with the cumulative volume of water fluid, tightens the lid of allotment bottle, bottle will be allocated with hand or manipulator
Shake the frequency of at least 1 time in being shaken in 1 second, allotment bottle is shaken rolling at most 5 seconds, allotment bottle shake rolling when, allocate each displacement of bottle
Distance be not less than 10 centimetres, and the remaining space of mixed liquor to allotment bottle move, preferably make mixed liquor to allocating bottle
Remaining space moves and impacts the lid of allotment bottle, as stated above, you can form homogeneous emulsion, the emulsion is in room temperature
Lower standing 5min is in still homogeneous emulsion, is not layered；The allotment bottle, it is vial with cover, plastic bottle with cover, band
The aluminium of lid-modeling carton, canister with cover, for example, macromolecule PET bottle, high-density polyethylene bottle bottle, etc.；It is with cover be for
Lid can be tightened and shake and shake the operation of allotment, the volume for preferably allocating bottle is not more than 3 liters, such as the appearance of preferred allotment bottle
Product is 0.5 liter, and the aqueous-based liquid includes the liquid of water, water content more than 60%, or the aqueous solution containing ethanol, such as
The water fluid is selected from the aqueous solution of following one or more materials：It is sucrose, glucose, fructose, maltose, chitosan oligosaccharide, low
Fructooligosaccharides, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid, asparagus fern acyl
Amine, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid, nicotinic acid, courage
Alkali, inositol.
Embodiment 2, hydrophilic lipid composite, it is prepared and concocting method.
Hydrophilic lipid composite, recipe quantity by weight percentage, contain respectively：
Wherein, the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil；Alpha-linolenic acid
Donor plant grease separation from linseed oil, Purple Perilla Seed Oil, pumpkin seed oil, peony seed oil, eucommia ulmoides seed oil or oil and fat of sacha inchi；γ-Asia
The donor grease separation of numb acid is from gamma-linolenic acid oil；Linoleic donor plant grease separation is from soybean oil, corn oil, peanut oil, sunflower
Seed oil, olive oil, silybum marianum seed oil, pumpkin seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower
Seed oil, grape-kernel oil, Suaeda salsa seed oil, wheat-germ oil, maize germ oil, smooth bark Lai wood fruit oil, rhus glabra oil, tree peony
Seed oil, samara oil, imperial rice bran oil, tomato seed oil, Fructus Zanthoxyli oil, canola, Camellia oil (including tea seed oil, camellia seed oil or
Tea oil), rice bran oil, shea butter, borage oil, capsicum seed oil, coconut oil or cottonseed oil；The donor plant grease separation of oleic acid is certainly
Soybean oil, corn oil, peanut oil, sunflower oil, olive oil, pumpkin seed oil, silybum marianum seed oil, amygdalus pedunculata pall oil, palm oil, sesame
Sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran oil, capsicum seed oil, granada seed oil, brucea fruit oil or coconut palm
In seed oil；The donor vegetable and animals oils of nervonic acid include acer truncatum seed oil or shark oil；DHA donor vegetable and animals oils include DHA algal
Oil, krill oil, fish oil or fish oil extract；EPA donor vegetable and animals oils include krill oil, fish oil or fish oil extract.
Preparation method：Its preparation method is with being preparation method one, preparation method two or the preparation method three-phase in embodiment 1
Together, the preparation method in embodiment 1 can be completely suitable for the present embodiment.
Allotment：The hydrophily lipid composite water fluid of any one proportioning is shaken to be deployed into milkiness by shaking
Liquid, preferably described water fluid are selected from the aqueous solution of following one or more materials：Sucrose, glucose, fructose, maltose, shell
Oligosaccharides, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid,
Asparagine, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid,
Nicotinic acid, choline, inositol, or water fluid are selected from the water of animal emulsion, the aqueous emulsion of animal albumen powder or plant protein powder
Emulsion.
Embodiment 3, hydrophilic lipid composite, it is prepared and concocting method.
Hydrophilic lipid composite, recipe quantity by weight percentage, contain respectively：
Wherein, the phosphatide includes soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil；It is linoleic
Donor plant grease separation is flat from soybean oil, corn oil, peanut oil, sunflower oil, olive oil, silybum marianum seed oil, pumpkin seed oil, long handle
Peach oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, Suaeda salsa seed oil, wheat-germ oil,
Maize germ oil, smooth bark Lai wood fruit oil, rhus glabra oil, peony seed oil, samara oil, imperial rice bran oil, tomato seed oil, Fructus Zanthoxyli oil,
Canola, Camellia oily (including tea seed oil, camellia seed oil or tea oil), rice bran oil, capsicum seed oil, granada seed oil, crow courage
Seed oil or coconut oil；The donor plant grease separation of oleic acid is from soybean oil, corn oil, peanut oil, sunflower oil, olive oil, pumpkin
Oil, silybum marianum seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran
Oil, capsicum seed oil or coconut oil.
Preparation method：Its preparation method is with being preparation method one, preparation method two or the preparation method three-phase in embodiment 1
Together, the preparation method in embodiment 1 can be completely suitable for the present embodiment.
Allotment：The hydrophily lipid composite water fluid of any one proportioning is shaken to be deployed into milkiness by shaking
Liquid, such as preferred water fluid are selected from the aqueous solution of following one or more materials：Sucrose, glucose, fructose, maltose, shell
Oligosaccharides, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid,
Asparagine, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid,
Nicotinic acid, choline, inositol, or water fluid are selected from the water of animal emulsion, the aqueous emulsion of animal albumen powder or plant protein powder
Emulsion.
Embodiment 4, hydrophilic lipid composite, it is prepared and concocting method.
Hydrophilic lipid composite, recipe quantity by weight percentage, contain respectively：
Wherein, the phosphatide is selected from soybean lecithin, soybean lecithin, yolk phospholipid, egg yolk lecithin or krill oil；Alpha-linolenic acid
Donor plant oil include linseed oil, Purple Perilla Seed Oil, pumpkin seed oil, peony seed oil, eucommia ulmoides seed oil or oil and fat of sacha inchi；γ-Asia
The donor grease separation of numb acid is from gamma-linolenic acid oil；Linoleic donor plant grease separation is from soybean oil, corn oil, peanut oil, sunflower
Seed oil, olive oil, silybum marianum seed oil, pumpkin seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, Semen Juglandis oil, rapeseed oil, safflower
Seed oil, grape-kernel oil, Suaeda salsa seed oil, wheat-germ oil, maize germ oil, smooth bark Lai wood fruit oil, rhus glabra oil, tree peony
Seed oil, samara oil, imperial rice bran oil, tomato seed oil, Fructus Zanthoxyli oil, canola, Camellia oil (including tea seed oil, camellia seed oil or
Tea oil), rice bran oil, capsicum seed oil, granada seed oil, brucea fruit oil or coconut oil；The donor plant grease separation of oleic acid from soybean oil,
Corn oil, peanut oil, sunflower oil, olive oil, pumpkin seed oil, silybum marianum seed oil, amygdalus pedunculata pall oil, palm oil, sesame oil, core
Persic oil, rapeseed oil, safflower seed oil, grape-kernel oil, rice bran oil, capsicum seed oil or coconut oil.
Preparation method：Its preparation method is with being preparation method one, preparation method two or the preparation method three-phase in embodiment 1
Together, the preparation method in embodiment 1 can be completely suitable for the present embodiment.
Allotment：The hydrophily lipid composite water fluid of any one proportioning is shaken to be deployed into milkiness by shaking
Liquid, such as preferred water fluid are selected from the aqueous solution of following one or more materials：Sucrose, glucose, fructose, maltose, shell
Oligosaccharides, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid,
Asparagine, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid,
Nicotinic acid, choline, inositol, or water fluid are selected from the water of animal emulsion, the aqueous emulsion of animal albumen powder or plant protein powder
Emulsion.
Embodiment 5, hydrophilic the lipid composite fast deployment performance and packaged combination of embodiment 2 to embodiment 4.
The hydrophilic lipid composite that any one is matched into embodiment 4 of Example 2, has good fast velocity modulation
With performance.
Fast deployment performance：The hydrophily lipid composite that any one in embodiment matches and water fluid are poured into tune
With in bottle, the weight ratio of wherein water fluid and hydrophilic lipid composite is more than 3:1, preferably water fluid with it is hydrophilic
The weight ratio of lipid composite is more than 10:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than allotment bottle and hold
The 50% of amount, the lid of allotment bottle is tightened, will allocate bottle in the frequency of shaking at least 1 time of being shaken in 1 second with hand or manipulator, make tune
Shaken rolling at most 5 seconds with bottle, allotment bottle shake rolling when, the distance of the allotment each displacement of bottle is not less than 10 centimetres, and makes mixed liquor
Moved to the remaining space of allotment bottle, preferably move the remaining space of mixed liquor to allotment bottle and impact the lid of allotment bottle,
As stated above, you can form homogeneous emulsion, it is in still homogeneous emulsion that the emulsion stands 5min at room temperature, is not occurred
Layering；The allotment bottle, is vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, canister with cover, example
Such as, macromolecule PET bottle, high-density polyethylene bottle bottle, etc.；It is with cover to be to be able to tighten lid and shake to shake the behaviour of allotment
Make, the volume for preferably allocating bottle is not more than 3 liters, such as the volume of preferred allotment bottle is 0.5 liter, and the aqueous-based liquid includes
Water, water content are more than 60% liquid, or the aqueous solution containing ethanol, such as including but not limited to animal emulsion, fruit juice, fruit
Vegetable beverage, plant extraction liquid or beverage, carbohydrate solutions or beverage, vegetable protein beverage, the aqueous emulsion of animal milk powder, ammonia
Aqueous solution of base acid, etc..
Packaged combination：A kind of packaging compositions, including the hydrophily lipid composite that any one in embodiment is matched
Independent packaging, and be present in simultaneously in same packing box or same packaging bag with allotment bottle, the allotment bottle is with lid
The empty bottle of son；Or the water fluid of certain volume is pre-loaded with the allotment bottle, for aliphatic acid composition is directly added
Enter to allocate bottle, shaken by shaking to form homogeneous emulsion；Or in the packaging compositions, hydrophily lipid composite it is only
Vertical packaging is to be present in simultaneously in a packing box or packaging bag or fixed by pasting fixed, label with allotment bottle
Mode form assembly packaging or Packaging Bottle equipped with hydrophily lipid composite or packaging bag with allotment bottle to pack
The form of external member is fixed together, or the hydrophily fat matched in the packaging compositions containing any one in the present embodiment
Based composition, and be embodied with by shaking shaking hydrophily lipid composite and water fluid to obtain emulsion on its label
Content.The volume summation of wherein described water fluid and hydrophily lipid composite is not more than the container capacity for accommodating water fluid
Or the 98% of allotment bottle capacity.
Packaged combination：The independent sealed lid structure in container of hydrophily lipid composite that any one in embodiment is matched
In the chamber of part, water fluid is sealed in container, and opening of the The lid component of container installed in container is entered to container
Row sealing so that lipid composite is each independent sealed with water fluid, when in use, the The lid component of container is opened, release
The lipid composite gone out in The lid component, mix with the water fluid in container, further, shaken by shaking to form homogeneous milkiness
Liquid；
Or the lipid composite in the chamber of the The lid component of container is injected into water in the form of a diameter of 0.4mm~2mm fluid column
In base fluid body, such as gases at high pressure in the chamber for passing through the The lid component of container eject lipid composite, or pass through
Piston pressurization, the mode injected eject lipid composite, lipid composite is mixed with water fluid, shake and shake and formed
Emulsion, the water fluid include the liquid of water, water content more than 60%, or the aqueous solution containing ethanol.Wherein described water
Base fluid body and 98% of the volume summation of hydrophily lipid composite no more than the container capacity for accommodating water fluid.
The hydrophily lipid composite of any proportioning, takes 1 gram of hydrophily lipid group in embodiment 6, embodiment 1~4
Compound, 2~150 milliliters of water fluid is added, shaken through shaking, in 5 seconds, or even emulsion can be formed in 1 second, also,
The emulsion of formation is being stored at room temperature more than 5min, can keep being stabilized, and can keep homogeneous, stably, lamination does not occur；
Or pour into hydrophily lipid composite and water fluid in allotment bottle, its reclaimed water or water content are water base more than 60%
The weight ratio of liquid and hydrophilic lipid composite is more than 3:1, the preferably weight of water fluid and hydrophilic lipid composite
Amount is than being more than 10:1, the cumulative volume of hydrophily lipid composite and water fluid is no more than the 70% of allotment bottle capacity, tighten tune
Lid with bottle, bottle will be allocated in the frequency of shaking at least 2 times of being shaken in 1 second with hand or manipulator, allotment bottle is shaken rolling at most 5 seconds
Clock, allotment bottle shake rolling when, the distance of the allotment each displacement of bottle is not less than 10 centimetres, and makes the residue of mixed liquor to allotment bottle empty
Between move, preferably make mixed liquor to allotment bottle remaining space move and impact allocate bottle lid, as stated above, you can shape
Into homogeneous emulsion, it is in still homogeneous emulsion that the emulsion stands 5min at room temperature, is not layered；The allotment bottle,
Can be vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, canister with cover.
Any proportioning contains emulsifying agent and liquid aliphatic hydrophily lipid group in embodiment 7, embodiment 1~4
Compound by being mixed with water fluid, and further through shake shake and be deployed into emulsion, prepare or allocate medicine, special medicine
Application in terms of purposes formula food, health food, nutraceutical or cosmetics.
Claims (11)
1. a kind of packaging compositions, including hydrophily lipid composite is independently packed and combined one with water fluid
Rise, the hydrophily lipid composite contains liquid aliphatic and emulsifying agent, and wherein liquid aliphatic is selected from following one or more things
Matter：Medium chain triglyceride, alpha-linolenic acid, gamma-Linolenic acid, diglyceride, oleic acid, linoleic acid, middle long chain fatty acids, liquid aliphatic
Content in hydrophily lipid composite is more than 45% with weight ratio meter；
Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol ester
Fat acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, department
Disk 40, sorbester p18, sorbester p38, sorbester p17, content of the emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.05%~
8%；
The water fluid is selected from the aqueous solution of following one or more materials：Sucrose, glucose, fructose, maltose, shell are few
Sugar, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid, day
Winter acid amides, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid, cigarette
Acid, choline, inositol, or, the water fluid is selected from animal emulsion, the aqueous emulsion of animal albumen powder or plant protein powder
Aqueous emulsion；
The weight ratio of the water fluid and hydrophily lipid composite is more than 3:1；
The volume summation of the water fluid and hydrophily lipid composite is not more than the container capacity of receiving water fluid
98%。
2. packaging compositions according to claim 1, the liquid aliphatic be selected from medium chain triglyceride and it is following a kind of or
Many kinds of substance：Oleic acid, linoleic acid, leukotrienes, diglyceride, middle long chain fatty acids, wherein medium chain triglyceride is in hydrophily fat
Content in based composition is using weight ratio meter as 30%~99%.
3. packaging compositions according to claim 1, the emulsifying agent is selected from phosphatide and following one or more materials：Sugarcane
Sugar fatty acid ester, list, diglycerine fatty acid ester, polyglyceryl fatty acid ester, methyl glycol fatty acid ester, lactic acid fatty glyceride,
Polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40, sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent is in parent
Content in aqueous lipid composition is using weight ratio meter as 0.1%~4%.
4. packaging compositions according to claim 1, the content of the lecithin in the phosphatide is more than 40%.
5. packaging compositions according to claim 1, further contain fat-soluble thing in the hydrophily lipid composite
Matter B, the liposoluble substance B are selected from following one or more materials：Nervonic acid, DHA, EPA, arachidonic acid, vitamin E,
Vitamin A, vitamin D, CLA, conjugated linoleic acid glyceride, phosphatidylserine, phytosterol, phytosterin ester,
Plant stanol ester, rice bran fats alkanol, Polyene Phosphatidylcholine, wherein liposoluble substance B is in hydrophily lipid composite
Content using weight ratio meter as 0.01%~30%.
6. a kind of packaging compositions, including hydrophily lipid composite is independently packed and combined one with water fluid
Rise, the hydrophily lipid composite contains liquid aliphatic, nervonic acid and emulsifying agent, wherein liquid aliphatic be selected from it is following a kind of or
Many kinds of substance：Alpha-linolenic acid, gamma-Linolenic acid, medium chain triglyceride, diglyceride, middle long chain fatty acids, liquid aliphatic is hydrophilic
Property lipid composite in content with weight ratio meter be more than 45%；
Content of the nervonic acid in hydrophily lipid composite is using weight ratio meter as 0.01%~30%
Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol ester
Fat acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, department
Disk 40, sorbester p18, sorbester p38, sorbester p17, content of the emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.05%~
8%；
The water fluid is selected from the aqueous solution of following one or more materials：Sucrose, glucose, fructose, maltose, shell are few
Sugar, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid, day
Winter acid amides, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid, cigarette
Acid, choline, inositol；
The weight ratio of the water fluid and hydrophily lipid composite is more than 3:1；
The volume summation of the water fluid and hydrophily lipid composite is not more than the container capacity of receiving water fluid
98%。
7. a kind of packaging compositions, including hydrophily lipid composite is independently packed and combined one with water fluid
Rise, the hydrophily lipid composite is selected from following one kind：
The hydrophily lipid composite contains medium chain triglyceride and emulsifying agent,
The hydrophily lipid composite contains alpha-linolenic acid and emulsifying agent,
The hydrophily lipid composite contains gamma-Linolenic acid and emulsifying agent,
The hydrophily lipid composite contains DHA and emulsifying agent,
The hydrophily lipid composite contains EPA and emulsifying agent,
The hydrophily lipid composite contains arachidonic acid and emulsifying agent,
The hydrophily lipid composite contains vitamin E and emulsifying agent；
Emulsifying agent is selected from following one or more materials：Phosphatide, sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol ester
Fat acid esters, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, department
Disk 40, sorbester p18, sorbester p38, sorbester p17, content of the emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.05%~
8%；
The water fluid is selected from the aqueous solution of following one or more materials：Sucrose, glucose, fructose, maltose, shell are few
Sugar, FOS, xylo-oligosaccharide, polydextrose, inulin, taurine, cysteine, cystine, glycine, aspartic acid, day
Winter acid amides, glutamic acid, glutamine, lysine, arginine, ornithine, vitamin C, vitamin B, l-cn, folic acid, cigarette
Acid, choline, inositol；
The weight ratio of the water fluid and hydrophily lipid composite is more than 3:1；
The volume summation of the water fluid and hydrophily lipid composite is not more than the container capacity of receiving water fluid
98%。
8. any one packaging compositions described in claim 6 or claim 7, breast in the hydrophily lipid composite
Agent is selected from phosphatide and following one or more materials：Sucrose fatty ester, list, diglycerine fatty acid ester, polyglycerol fatty acid
Ester, methyl glycol fatty acid ester, lactic acid fatty glyceride, polysorbas20, polysorbate40, polysorbate60, Tween 80, span 20, span 40,
The content of sorbester p18, sorbester p38, sorbester p17, wherein emulsifying agent in hydrophily lipid composite using weight ratio meter as 0.1%~
4%。
9. packaging compositions according to claim 1, the hydrophily lipid composite is prepared using following methods：It is wrapped
Include：
(1) dispensing：Emulsifying agent, liquid aliphatic and other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed
Splitting or integrating dissipates uniform；
(2) liquid prepared in (1) is placed in emulsion tank, heating makes fluid temperature be more than 45 DEG C, big in speed of agitator
Under conditions of 500r/min, be stirred 3~25min of operation, then in 3~5min rapidly by liquid cooling to 25 DEG C with
Under, stop stirring, stand；Or the liquid prepared in (1) is placed in emulsion tank, heating make fluid temperature for 45 DEG C with
On, in homogenizer carry out pressure be 20~58MPa homogeneous, then in 3~5min rapidly by liquid cooling to 25 DEG C with
Under, stop stirring；
(3) it is filling：Oily liquids is subjected to vacuum outgas, it is filling, sealing, packaging, examine, produce.
10. packaging compositions according to claim 1, the hydrophily lipid composite is prepared using following methods：It
Including：
(1) dispensing：Emulsifying agent, liquid aliphatic and other liposoluble substances are weighed by formula, is settled to required output, stirring is mixed
Splitting or integrating dissipates uniform；
(2) liquid prepared in (1) is placed in emulsion tank, nitrogen is continually fed into oily liquids or keeps emulsion tank
In pressure be more than 1.3 atmospheric pressure, and be stirred 3~25min of operation under conditions of speed of agitator is more than 300r/min, make
The oily liquids of the foam type rich in nitrogen of nontransparent shape is presented in oily liquids, stops stirring；
(3) it is filling：Will（2）The oily liquids of middle preparation is filling in container, further container is carried out to be filled with nitrogen, and make appearance
Gas pressure intensity is more than 1.2 atmospheric pressure in device, pressurizing window, packaging, examines, produces.
11. hydrophily lipid composite is deployed into the side of emulsion with water fluid in the packaging compositions described in claim 1
Method, including：Hydrophily lipid composite is poured into the container for accommodating water fluid, makes hydrophily lipid composite and water base
The cumulative volume of liquid is no more than the 98% of container capacity, tightens the lid of container, and bottle will be allocated in 1 second with hand or manipulator
Shake and shake the frequency of at least 1 time, container rolling of shaking is no more than 10 seconds, container shake rolling when, the distance of each displacement of container is not less than
10 centimetres, and mixed liquor is moved to the remaining space of container and impact the lid of allotment bottle and form emulsion；
The container of the water fluid, selected from vial with cover, plastic bottle with cover, aluminium with cover-modeling carton, gold with cover
Belong to container, and the volume of container is not more than 3 liters.
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| CN201610834100 | 2016-09-20 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109602009A (en) * | 2018-08-07 | 2019-04-12 | 丽睿客信息科技（北京）有限公司 | Weight losing function food |
| CN112294790A (en) * | 2019-08-01 | 2021-02-02 | 宁波特壹食品有限公司 | Immunity nutrient supplement and preparation method thereof |
| CN112618582A (en) * | 2020-12-18 | 2021-04-09 | 拉格比(广东)健康科技有限公司 | Algae oil-containing DHA composition and preparation method thereof |
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| CN104490774A (en) * | 2014-12-11 | 2015-04-08 | 福州乾正药业有限公司 | Water emulsifier composition containing nervonic acid as well as preparation method and application thereof |
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| CA2388339A1 (en) * | 1999-11-04 | 2001-05-10 | Monsanto Technology Llc | Cholesterol reducing sterol compositions, preparation and method of use |
| CN103190631A (en) * | 2008-03-20 | 2013-07-10 | 维尔恩公司 | Compositions containing non-polar compounds and method for manufacturing phytosterol |
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| CN109602009A (en) * | 2018-08-07 | 2019-04-12 | 丽睿客信息科技（北京）有限公司 | Weight losing function food |
| CN112294790A (en) * | 2019-08-01 | 2021-02-02 | 宁波特壹食品有限公司 | Immunity nutrient supplement and preparation method thereof |
| CN112618582A (en) * | 2020-12-18 | 2021-04-09 | 拉格比(广东)健康科技有限公司 | Algae oil-containing DHA composition and preparation method thereof |
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