CN107693641A - A kind of massage creams for alleviating mastitis - Google Patents
A kind of massage creams for alleviating mastitis Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention discloses a kind of massage creams for alleviating mastitis, raw material group is：Semen vaccariae extraction, full Fructus Trichosanthis extract, dandelion extract, cabbage extract, cucumber berry extract, grape seed extract, Lavender.The invention also discloses the preparation method of creams.Drug regimen use of the present invention has no toxic side effect than alone several extract significant effects.
Description
Technical field
The present invention relates to one kind to massage creams, and in particular to a kind of massage creams for alleviating mastitis.
Background technology
Mastitis is the common disease of women, can be divided into acute purulent mammitis, by mammary areola according to the difference of the cause of disease
Fistula, plasma cell mastitis etc., stated herein with most common acute purulent mammitis.Acute purulent mammitis is normal
Betide in nursing period, particularly 1~2 month primipara's postpartum, therefore be called acute nursing period or puerperium suppurative mastitis,
The traditional Chinese medical science is referred to as " acute mastitis ".The incidence of disease of primipara's acute mastitis is up to 2%~4%, 1 times more than multipara mastitis.Milk
Alluvial occurs together bacterium infection and fallen ill, and is showed in acute inflammation, red and swollen heat pain, high fever of shivering with cold, in early days can be with gimmick milk ejection, Chinese medicine
Treatment, then need incision and drainage after suppurating.Not only puerpera's pain is abnormal after morbidity, and can not continue lactation, influences
The health of baby.
The product for mastitis is mainly Chinese patent drug in the market, and the device for also having some such as brassieres etc is used for
Alleviate mastitis, but lack the creams or massage cream for alleviating mastitis.
The content of the invention
The present invention discloses a kind of massage creams for alleviating mastitis to solve problem of the prior art.
The purpose of the present invention is realized by following technical proposal：
A kind of massage creams for alleviating mastitis, raw material composition and proportioning are：Semen vaccariae extraction 0.5-10%v/v,
1~5%v/v of full Fructus Trichosanthis extract, 0.1~10%v/v of dandelion extract, 1~10%v/v of cabbage extract, cucumber fruit
0.5~5%v/v of extract, 0.1~5%v/v of grape seed extract, 0.5~5%v/v of Lavender.
Preferably, the massage creams of described alleviation mastitis, raw material composition and proportioning are：Semen vaccariae extraction 10%
V/v, full Fructus Trichosanthis extract 5%v/v, dandelion extract 8%v/v, cabbage extract 7%v/v, cucumber berry extract
2.5%v/v, grape seed extract 4%v/v, Lavender 3%v/v.
Preferably, the massage creams of described alleviation mastitis, raw material composition and proportioning are：Semen vaccariae extraction 8%
V/v, full Fructus Trichosanthis extract 2%v/v, dandelion extract 6%v/v, cabbage extract 6%v/v, cucumber berry extract 2%
V/v, grape seed extract 3%v/v, Lavender 4%v/v.
Preferably, the massage creams of described alleviation mastitis, raw material composition and proportioning are：Semen vaccariae extraction 5%
V/v, full Fructus Trichosanthis extract 1%v/v, dandelion extract 5%v/v, cabbage extract 5%v/v, cucumber berry extract 1%
V/v, grape seed extract 1%v/v, Lavender 1%v/v.
Preferably, semen vaccariae extraction is seed of cowherb extract solution；Full Fructus Trichosanthis extract is full Snakegourd Fruit extract solution；Pu Gong
English extract is dandelion extract solution；Cabbage extract is cabbage extract solution, cucumber berry extract be cucumber fruit extract solution,
Grape seed extract is grape pip extract solution.
The massage creams of described alleviation mastitis, in addition to oil phase substrate and aqueous phase base, described auxiliary material be GTCC,
It is dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, sweet
Oleostearin acid esters, propane diols, Magnesiumaluminumsilicate.
The massage creams for alleviating mastitis, auxiliary material and proportioning are GTCC 2-10%v/v, dimethicone 1-5%v/
V, SIMMONDSIA CHINENSIS SEED OIL 5-10%v/v, cetanol 1-10%w/v, stearic acid 1-10%w/v, card ripple 0.1-1%w/v, triethanolamine
0.1-1%v/v, butanediol 5-10%v/v, glycerine 5-10%v/v, PCA-NA 1-10%v/v, EDTA-NA 0.1-1%w/v,
Stearine 1-5%w/v, propane diols 1-5%v/v, Magnesiumaluminumsilicate 0.1-1%w/v.
The preparation method of the massage creams for alleviating mastitis, step are：
(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, 70~80 DEG C of agitating and heatings are standby
With；
(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, silicon
After sour magnalium mixing, it is dissolved in water, 80~100 DEG C of 10~30min of agitating and heating, 70~80 DEG C standby；
(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；
(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug,
It is well mixed, both.
Preferably, the preparation method of the massage creams of described alleviation mastitis, step are：
(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, SIMMONDSIA CHINENSIS SEED OIL is settled to 20ml,
70~75 DEG C of agitating and heatings, it is standby；
(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, silicon
After sour magnalium mixing, it is dissolved in water, is settled to 80ml, 90~100 DEG C of agitating and heating 20min, 70~80 DEG C standby；
(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；
(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug,
It is well mixed, both.
Preferably, described preservative is Phenoxyethanol and/or Sensiva SC50.
Above-mentioned all extracts are liquid extract solution, are bought from market.
The seed of cowherb restores menstrual flow and invigorates blood circulation in side, the lower breast carbuncle that disappears is monarch, and compatibility dandelion is clearing heat and detoxicating, dispersing swelling and dissipating binds are ministerial drug,
Relieving stuffiness of the chest by dispersing aggregation of pathogens, it is for adjutant, cabbage heat-clearing eliminating stagnation to stop pain, cucumber fruit, grape pip, lavender more with full Snakegourd Fruit clearing away heat and eliminating phlegm
Clearing heat and detoxicating, it is to make medicine to adjust with essential oil, and priming enter liver, concurrence dispersing stagnated hepatoqi is promoting blood circulation and removing blood stasis, the effect of carbuncle that disappears dissipating bind.
There is promoting circulation of blood to stimulate the menstrual flow, expedite the emergence of lower breast, healing up sore and subduing swelling and other effects for the monarch drug in a prescription seed of cowherb.The seed of cowherb increases breast activity effectively
Composition is mainly dibutyl phthalate, ministerial drug dandelion bitter, sweet, and cold in nature, tool is clearing heat and detoxicating, and dispersing swelling and dissipating binds, diuresis is led to
The medical research of the effect of leaching shows that dandelion has broad-spectrum antibacterial effect, full Snakegourd Fruit clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation.
Cabbage extract has very strong oxidation resistance, it is possible to reduce the oxidative pressure caused by free radical, grape seed extract
It is that isolated a kind of polyphenols is extracted from grape pip, mainly by OPC, catechin, epicatechin, does not eat
The polyphenols composition such as sub- acid, L-Epicatechin gallate.Containing abundant vitamin E in cucumber, cucumber chitinase, have very strong
Bioactivity, the metabolism of body can be effectively facilitated, there is moisturizing, unfold wrinkle effect.
The useful achievement of the present invention：
The creams that the product of the present invention is easily absorbed using fine and smooth lubrication with the addition of natural plant extracts, more as substrate
The drug effect of prescription, and medicine is applied in combination than alone several extract significant effects in side, and have no toxic side effect.Inventor is also logical
Contrast is crossed merely using gimmick and the effect of creams combination gimmick, it was demonstrated that creams combination gimmick is better than using gimmick merely.
Embodiment
The invention will be further described with experimental example with reference to embodiments, and following examples and experimental example are only used for
The bright present invention, but the invention scope of the present invention is not limited to, the technician of technical field can be according to above-mentioned hair
Bright content makes the modifications and adaptations of some non-intrinsically safes.
Seed of cowherb extract solution and full Snakegourd Fruit extract solution are purchased from Shanghai Ji Yan bio tech ltd, lavender extraction
Liquid, dandelion extract solution, grape pip extract solution, cucumber fruit extract solution, cabbage extract solution have purchased from the Quzhou grand biotechnology of exhibition
Limit company.
Embodiment 1：A kind of massage creams for alleviating mastitis, raw material composition and proportioning are：Semen vaccariae extraction 0.5-
10%v/v, complete 1~5%v/v of Fructus Trichosanthis extract, 0.1~10%v/v of dandelion extract, 1~10%v/ of cabbage extract
V, 0.5~5%v/v of cucumber berry extract, 0.1~5%v/v of grape seed extract, 0.5~5%v/v of Lavender；
Semen vaccariae extraction is seed of cowherb extract solution；Full Fructus Trichosanthis extract is full Snakegourd Fruit extract solution；Dandelion is extracted
Thing is dandelion extract solution；Cabbage extract is cabbage extract solution, cucumber berry extract is cucumber fruit extract solution, grape pip
Extract is grape pip extract solution；
The massage creams of described alleviation mastitis, in addition to oil phase substrate and aqueous phase base, described auxiliary material be GTCC,
It is dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, sweet
Oleostearin acid esters, propane diols, Magnesiumaluminumsilicate；
The massage creams for alleviating mastitis, auxiliary material and proportioning are GTCC 2-10%v/v, dimethicone 1-5%v/
V, SIMMONDSIA CHINENSIS SEED OIL 5-10%v/v, cetanol 1-10%w/v, stearic acid 1-10%w/v, card ripple 0.1-1%w/v, triethanolamine
0.1-1%v/v, butanediol 5-10%v/v, glycerine 5-10%v/v, PCA-NA 1-10%v/v, EDTA-NA 0.1-1%w/v,
Stearine 1-5%w/v, propane diols 1-5%v/v, Magnesiumaluminumsilicate 0.1-1%w/v；
Preparation method, step are：
(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, SIMMONDSIA CHINENSIS SEED OIL is settled to 20ml,
70~75 DEG C of agitating and heatings, it is standby；
(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, silicon
After sour magnalium mixing, it is dissolved in water, is settled to 80ml, 90~100 DEG C of agitating and heating 20min, 70~80 DEG C standby；
(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；
(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug,
It is well mixed, both；
Described preservative is Phenoxyethanol and Sensiva SC50.
Embodiment 2：A kind of massage creams for alleviating mastitis, raw material composition and proportioning are：Raw material forms and proportioning is：King
Do not stay row extract 10%v/v, full Fructus Trichosanthis extract 5%v/v, dandelion extract 8%v/v, cabbage extract 7%v/v,
Cucumber berry extract 2.5%v/v, grape seed extract 4%v/v, Lavender 3%v/v；
Semen vaccariae extraction is seed of cowherb extract solution；Full Fructus Trichosanthis extract is full Snakegourd Fruit extract solution；Dandelion is extracted
Thing is dandelion extract solution；Cabbage extract is cabbage extract solution, cucumber berry extract is cucumber fruit extract solution, grape pip
Extract is grape pip extract solution；
The massage creams of described alleviation mastitis, in addition to oil phase substrate and aqueous phase base, described auxiliary material be GTCC,
It is dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, sweet
Oleostearin acid esters, propane diols, Magnesiumaluminumsilicate；
The massage creams for alleviating mastitis, auxiliary material and proportioning are GTCC 2-10%v/v, dimethicone 1-5%v/
V, SIMMONDSIA CHINENSIS SEED OIL 5-10%v/v, cetanol 1-10%w/v, stearic acid 1-10%w/v, card ripple 0.1-1%w/v, triethanolamine
0.1-1%v/v, butanediol 5-10%v/v, glycerine 5-10%v/v, PCA-NA 1-10%v/v, EDTA-NA 0.1-1%w/v,
Stearine 1-5%w/v, propane diols 1-5%v/v, Magnesiumaluminumsilicate 0.1-1%w/v；
Preparation method, step are：
(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, SIMMONDSIA CHINENSIS SEED OIL is settled to 20ml,
70~75 DEG C of agitating and heatings, it is standby；
(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, silicon
After sour magnalium mixing, it is dissolved in water, is settled to 80ml, 90~100 DEG C of agitating and heating 20min, 70~80 DEG C standby；
(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；
(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug,
It is well mixed, both；
Described preservative is Phenoxyethanol.
Embodiment 3：A kind of massage creams for alleviating mastitis, raw material composition and proportioning are：Semen vaccariae extraction 8%v/
V, full Fructus Trichosanthis extract 2%v/v, dandelion extract 6%v/v, cabbage extract 6%v/v, cucumber berry extract 2%v/
V, grape seed extract 3%v/v, Lavender 4%v/v；
Semen vaccariae extraction is seed of cowherb extract solution；Full Fructus Trichosanthis extract is full Snakegourd Fruit extract solution；Dandelion is extracted
Thing is dandelion extract solution；Cabbage extract is cabbage extract solution, cucumber berry extract is cucumber fruit extract solution, grape pip
Extract is grape pip extract solution；
The massage creams of described alleviation mastitis, in addition to oil phase substrate and aqueous phase base, described auxiliary material be GTCC,
It is dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, sweet
Oleostearin acid esters, propane diols, Magnesiumaluminumsilicate；
The massage creams for alleviating mastitis, auxiliary material and proportioning are GTCC 2-10%v/v, dimethicone 1-5%v/
V, SIMMONDSIA CHINENSIS SEED OIL 5-10%v/v, cetanol 1-10%w/v, stearic acid 1-10%w/v, card ripple 0.1-1%w/v, triethanolamine
0.1-1%v/v, butanediol 5-10%v/v, glycerine 5-10%v/v, PCA-NA 1-10%v/v, EDTA-NA 0.1-1%w/v,
Stearine 1-5%w/v, propane diols 1-5%v/v, Magnesiumaluminumsilicate 0.1-1%w/v；
Preparation method, step are：
(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, SIMMONDSIA CHINENSIS SEED OIL is settled to 20ml,
70~75 DEG C of agitating and heatings, it is standby；
(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, silicon
After sour magnalium mixing, it is dissolved in water, is settled to 80ml, 90~100 DEG C of agitating and heating 20min, 70~80 DEG C standby；
(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；
(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug,
It is well mixed, both；
Described preservative is Sensiva SC50.
Embodiment 4：A kind of massage creams for alleviating mastitis, raw material composition and proportioning are：Semen vaccariae extraction 5%v/
V, full Fructus Trichosanthis extract 1%v/v, dandelion extract 5%v/v, cabbage extract 5%v/v, cucumber berry extract 1%v/
V, grape seed extract 1%v/v, Lavender 1%v/v；
Semen vaccariae extraction is seed of cowherb extract solution；Full Fructus Trichosanthis extract is full Snakegourd Fruit extract solution；Dandelion is extracted
Thing is dandelion extract solution；Cabbage extract is cabbage extract solution, cucumber berry extract is cucumber fruit extract solution, grape pip
Extract is grape pip extract solution；
The massage creams of described alleviation mastitis, in addition to oil phase substrate and aqueous phase base, described auxiliary material be GTCC,
It is dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, sweet
Oleostearin acid esters, propane diols, Magnesiumaluminumsilicate；
The massage creams for alleviating mastitis, auxiliary material and proportioning are GTCC 2-10%v/v, dimethicone 1-5%v/
V, SIMMONDSIA CHINENSIS SEED OIL 5-10%v/v, cetanol 1-10%w/v, stearic acid 1-10%w/v, card ripple 0.1-1%w/v, triethanolamine
0.1-1%v/v, butanediol 5-10%v/v, glycerine 5-10%v/v, PCA-NA 1-10%v/v, EDTA-NA 0.1-1%w/v,
Stearine 1-5%w/v, propane diols 1-5%v/v, Magnesiumaluminumsilicate 0.1-1%w/v；
Preparation method, step are：
(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, SIMMONDSIA CHINENSIS SEED OIL is settled to 20ml,
70~75 DEG C of agitating and heatings, it is standby；
(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, silicon
After sour magnalium mixing, it is dissolved in water, is settled to 80ml, 90~100 DEG C of agitating and heating 20min, 70~80 DEG C standby；
(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；
(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug,
It is well mixed, both；
Described preservative is Phenoxyethanol and Sensiva SC50.
Experimental example 1：
The puerpera of 120 generation galactostasises is collected, age 20-40 year, in 3-4 days postpartum, swollen breasts occur, touches breast
There is hard sense in room, and has tenderness, while is raised with body temperature, and 120 puerperas are divided into two groups.Observation group 60, control group 60
Example, two groups are compareing age, course of disease no significant difference, have comparativity.
Creams obtained by embodiment 2, combination with massaging gimmick, each breast are smeared three times in the morning, afternoon and evening to puerpera daily by observation group
Each 2ml, persistently massage 10 minutes.
Control group carries out identical manual massage three times in the morning, afternoon and evening to puerpera daily, persistently massages 10 minutes.
Effectively alleviation case load in one week is counted (effectively to alleviate and feel disappearance firmly for breast, no tenderness, body temperature is normal, as follows：
| Total number of persons | Effectively alleviate | It is not alleviated | It is efficient | |
| Observation group | 60 | 52 | 8 | 87% |
| Control group | 60 | 35 | 25 | 58% |
Observation group puerpera averagely effectively alleviated mastitis using three days, persistently using after one week, the mastitis of 87% puerpera
Alleviated, lump disappears, and body temperature is normal, and breast is without pain.
Control group puerpera passes through manual massage, the effective alleviation mastitis having, a couple of days time to several weeks, some several weeks
It can not disappear, the final intravenous injection antiphlogistic having just is alleviated.
Through statistics, one week efficient significant difference of observation group and control group, p<0.05, there is statistical significance.Explanation makes
With the product of the present invention, there is the effect for alleviating mastitis.
Experiment 2：Extracorporeal bacteria inhibitor test
The bacteria suspension of 0.2mL bacteriums, the coating of L-type spreader are added into beef extract-peptone flat board on superclean bench
Uniformly.4 holes equidistantly are made a call on culture medium with card punch, are respectively dropped into 1g/mL dandelion extract in hole, the seed of cowherb carries
Take thing, cabbage extract and mixed extract.It is repeated 3 times, calculates average antibacterial circle diameter.
Experimental data is visible：Dandelion extract, semen vaccariae extraction, cabbage extract are thin to common five kinds
Bacterium has certain bacteriostasis, but the mixture of three kinds of extracts can more effectively suppress the propagation of bacterium, illustrate what is shared
Effect is better than alone.
Claims (10)
- A kind of 1. massage creams for alleviating mastitis, it is characterised in that：Raw material forms and proportioning is：Semen vaccariae extraction 0.5- 10%v/v, complete 1~5%v/v of Fructus Trichosanthis extract, 0.1~10%v/v of dandelion extract, 1~10%v/ of cabbage extract V, 0.5~5%v/v of cucumber berry extract, 0.1~5%v/v of grape seed extract, 0.5~5%v/v of Lavender.
- 2. alleviate the massage creams of mastitis as claimed in claim 1, it is characterised in that：Raw material forms and proportioning is：King is not Stay row extract 10%v/v, full Fructus Trichosanthis extract 5%v/v, dandelion extract 8%v/v, cabbage extract 7%v/v, Huang Melon and fruit extract 2.5%v/v, grape seed extract 4%v/v, Lavender 3%v/v.
- 3. alleviate the massage creams of mastitis as claimed in claim 1, it is characterised in that：Raw material forms and proportioning is：King is not Stay row extract 8%v/v, full Fructus Trichosanthis extract 2%v/v, dandelion extract 6%v/v, cabbage extract 6%v/v, Huang Melon and fruit extract 2%v/v, grape seed extract 3%v/v, Lavender 4%v/v.
- 4. alleviate the massage creams of mastitis as claimed in claim 1, it is characterised in that：Raw material forms and proportioning is：King is not Stay row extract 5%v/v, full Fructus Trichosanthis extract 1%v/v, dandelion extract 5%v/v, cabbage extract 5%v/v, Huang Melon and fruit extract 1%v/v, grape seed extract 1%v/v, Lavender 1%v/v.
- 5. the massage creams of the alleviation mastitis as described in Claims 1-4 is any, it is characterised in that：Semen vaccariae extraction For seed of cowherb extract solution；Full Fructus Trichosanthis extract is full Snakegourd Fruit extract solution；Dandelion extract is dandelion extract solution；Cabbage Extract is cabbage extract solution, cucumber berry extract is cucumber fruit extract solution, grape seed extract is grape pip extract solution.
- 6. the massage creams of the alleviation mastitis as described in Claims 1-4 is any, it is characterised in that：Also include oil phase substrate With aqueous phase substrate, described auxiliary material be GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, card ripple, triethanolamine, Butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, Magnesiumaluminumsilicate.
- 7. alleviate the massage creams of mastitis as described in power claim 6, it is characterised in that：Described auxiliary material and proportioning is GTCC 2-10%v/v, dimethicone 1-5%v/v, SIMMONDSIA CHINENSIS SEED OIL 5-10%v/v, cetanol 1-10%w/v, stearic acid 1-10%w/ V, card ripple 0.1-1%w/v, triethanolamine 0.1-1%v/v, butanediol 5-10%v/v, glycerine 5-10%v/v, PCA-NA 1- 10%v/v, EDTA-NA 0.1-1%w/v, stearine 1-5%w/v, propane diols 1-5%v/v, Magnesiumaluminumsilicate 0.1- 1%w/v.
- 8. alleviate the preparation method of the massage creams of mastitis as described in power claim 7, it is characterised in that step is：(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, 70~80 DEG C of agitating and heatings are standby；(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, alumina silicate After magnesium mixing, it is dissolved in water, 80~100 DEG C of 10~30min of agitating and heating, 70~80 DEG C standby；(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug, mixing Uniformly, both.
- 9. alleviate the preparation method of the massage creams of mastitis as claimed in claim 8, it is characterised in that step is：(1) after mixing GTCC, dimethicone, SIMMONDSIA CHINENSIS SEED OIL, cetanol, stearic acid, SIMMONDSIA CHINENSIS SEED OIL is settled to 20ml, 70~ 75 DEG C of agitating and heatings, it is standby；(2) by card ripple, triethanolamine, butanediol, glycerine, PCA-NA, EDTA-NA, stearine, propane diols, alumina silicate After magnesium mixing, it is dissolved in water, is settled to 80ml, 90~100 DEG C of agitating and heating 20min, 70~80 DEG C standby；(3) 70~80 DEG C, step (1) and step (2) are obtained into solution and mixed, adds preservative；(4) step (3) is obtained into obtaining solution progress 3~5min of homogenization, is cooled to less than 50 DEG C, adds bulk drug, mixing Uniformly, both.
- 10. the preparation method of the massage creams of the alleviation mastitis as described in power claim 8 or 9, it is characterised in that：Described Preservative is Phenoxyethanol and/or Sensiva SC50.
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