CN107638556A - Treat Chinese medicine composition of rabbit gastroenteritis and preparation method thereof - Google Patents

Treat Chinese medicine composition of rabbit gastroenteritis and preparation method thereof Download PDF

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Publication number
CN107638556A
CN107638556A CN201711076387.9A CN201711076387A CN107638556A CN 107638556 A CN107638556 A CN 107638556A CN 201711076387 A CN201711076387 A CN 201711076387A CN 107638556 A CN107638556 A CN 107638556A
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China
Prior art keywords
chinese medicine
medicine composition
rabbit
gastroenteritis
parts
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CN201711076387.9A
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Chinese (zh)
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李迎梅
安同伟
孙建
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Tianjin Rebate Science and Technology Development Co Ltd
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Tianjin Rebate Science and Technology Development Co Ltd
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Priority to CN201711076387.9A priority Critical patent/CN107638556A/en
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Abstract

The present invention relates to a kind of Chinese medicine composition for treating rabbit gastroenteritis and preparation method thereof, the component and its ratio of weight and number of the Chinese medicine composition are respectively:10 30 parts of the root of herbaceous peony;10 20 parts of elscholtiza;5 20 parts of Fructus Aurantii;1 10 parts of silkworm excrement;1 10 parts of the bark of official magnolia;5 20 parts of cloves;1 10 parts of ginger;15 parts of radix glycyrrhizae.The present invention has the effect of antibacterial, anti-inflammatory, heat-clearing, antidiarrheal, and toxic side effect is small, is not likely to produce drug resistance, drug residue free, easy to use, cost is relatively low, meet safe veterinary drug, ensure the requirement of animal-derived food safety, be a kind of Chinese medicine composition of ideal treatment rabbit gastroenteritis.

Description

Treat Chinese medicine composition of rabbit gastroenteritis and preparation method thereof
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition for treating rabbit gastroenteritis and preparation method thereof.
Background technology
Rabbit gastroenteritis is to support a kind of common disease in rabbit production, and the rabbit at various ages, various seasons can occur, Wherein young rabbit invasion is most, and the death rate is higher.Its pathogenic factor is mainly improper diet relevant with rabbit, has most commonly eaten corruption Lose rotten feed or frost feed.Because bacteriotoxin or moldin stimulate or freezed stimulation of the feed to stomach lining, and cause Inflammation.Take or eat by mistake some drugses or chemical substance (heavy metal, herbicide, deinsectization medicine etc.) and luring for gastroenteritis occurs Cause.This course of disease is 1-7 days, acute person just death in 10 hours.Its Symptoms is sick rabbit anorexia, indigestion.Abdomen Rush down, two kinds of symptoms of constipation or alternating occur.Excrement is diluter, and some stenches are creamy white glue sample in green, some, and some also carries White or yellow mucus.Severe disease rabbit is extremely weak, and hair is chaotic matt, general weakness, does not like activity, tripe abdomen pain, curls up Contracting is motionless at one jiao.Clinical treatment common antibiotics etc. are treated, and make antibody-resistant bacterium increasing, medicine has residual in human body Stay the health for also directly threatening the mankind.Animal body easily absorbs Chinese medicine preparation, and toxic side effect is small, noresidue, without the resistance to the action of a drug, without dirt Dye, therefore it has natural advantage in terms of the treatment of In The Rabbit Stomach enteritis.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating rabbit gastroenteritis, the Chinese medicine composition, have The effect of antibacterial, anti-inflammatory, heat-clearing, antidiarrheal, have no toxic side effect, be not likely to produce drug resistance, bioavilability is high.
It is another object of the present invention to provide a kind of preparation method for the Chinese medicine composition for treating rabbit gastroenteritis.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition for treating rabbit gastroenteritis, component and its ratio of weight and number difference of its Chinese medicine composition For:
A kind of preparation method for the Chinese medicine composition for treating rabbit gastroenteritis is as follows the step of its preparation method:
(1) root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and radix glycyrrhizae are weighed respectively according to weight proportion, is crushed Into powder, and all pass through 80 mesh sieves respectively;
(2) root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and radix glycyrrhizae after being sieved in step (1) are put into mixed Close in tank, be sufficiently mixed uniformly, that is, the Chinese medicine composition finished product for the rabbit gastroenteritis that obtains medical treatment.
Advantages of the present invention and beneficial effect are:
1st, the root of herbaceous peony that contains in the Chinese medicine composition of this treatment rabbit gastroenteritis, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, The Chinese medicinal ingredients such as ginger and radix glycyrrhizae, it has good preventive and therapeutic effect, antibacterial action to gastroenteritis caused by bacterium and mould etc. Positive effect.
2nd, the Chinese medicine composition broad-spectrum high efficacy of this treatment rabbit gastroenteritis, steady quality, easily absorb, not by temperature and soda acid Degree influences, and can reach blood peak concentration of drug in the short period with extremely low concentration.
3rd, the present invention has the effect of antibacterial, anti-inflammatory, heat-clearing, antidiarrheal, and toxic side effect is small, has no drug resistance, drug residue free, Easy to use, cost is relatively low, meets safe veterinary drug, ensures the requirement of animal-derived food safety, is a kind of ideal treatment The Chinese medicine composition of rabbit gastroenteritis.
Embodiment
The present invention is described in further detail by following examples.It should be noted that:Following embodiments are illustrative, are not It is limited, it is impossible to limit protection scope of the present invention with following embodiments.
The root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and radix glycyrrhizae involved in the present invention can be commercially It is commercially available.
Embodiment 1
A kind of Chinese medicine composition for treating rabbit gastroenteritis, the component and its weight of its Chinese medicine composition are respectively:The root of herbaceous peony 10g;Elscholtiza 10g;Fructus Aurantii 5g;Silkworm excrement 1g;Bark of official magnolia 1g;Cloves 5g;Ginger 1g;Radix glycyrrhizae 1g.
A kind of preparation method for the Chinese medicine composition for treating rabbit gastroenteritis is as follows the step of preparation method:
(1) root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and radix glycyrrhizae are weighed respectively according to weight proportion, is crushed Into powder, and all pass through 80 mesh sieves respectively;
(2) root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and radix glycyrrhizae after being sieved in step (1) are put into mixed Close in tank, be sufficiently mixed uniformly, that is, the Chinese medicine composition finished product for the rabbit gastroenteritis that obtains medical treatment.
Embodiment 2
A kind of Chinese medicine composition for treating rabbit gastroenteritis, the component and its weight of its Chinese medicine composition are respectively:The root of herbaceous peony 30g;Elscholtiza 20g;Fructus Aurantii 20g;Silkworm excrement 10g;Bark of official magnolia 10g;Cloves 20g;Ginger 10g;Radix glycyrrhizae 5g.
The step of its preparation method, is the same as embodiment 1.
Embodiment 3
A kind of Chinese medicine composition for treating rabbit gastroenteritis, the component and its weight of its Chinese medicine composition are respectively:The root of herbaceous peony 20g;Elscholtiza 15g;Fructus Aurantii 17g;Silkworm excrement 5g;Bark of official magnolia 5g;Cloves 17g;Ginger 5g;Radix glycyrrhizae 3g.
The step of its preparation method, is the same as embodiment 1.
Clinical practice
In order to verify clinical therapeutic efficacy of the present invention to rabbit gastroenteritis, we enter in Shandong Dezhou rabbit cultivation base In The Rabbit Stomach enteritis treatment of having gone is tested.In experiment, every group of Chinese medicine composition is divided into basic, normal, high three dosage and animal is divided Group administration, compared with having carried out curative effect with the routine medication of rabbit gastroenteritis, is in so as to evaluate Chinese medicine composition of the present invention Rabbit stomach enteritis treatment effect and optimum amount.
1st, material and method
1.1 experimental animal
Selection gastroenteritis morbidity rabbit 100, every group 20.Raised according to normal feeding management program.
1.2 trial drug
The present invention is prepared by our company.
Sulphaguanidine tablet:0.5g × 1000 piece/bag, Shandong Linyi Jin Cui veterinary drugs Co., Ltd, product batch number * * * * * *
1.3 test method
The case of rabbit gastroenteritis is mainly made a definite diagnosis by incidence and clinical symptoms, then will be fallen ill by experimenter Rabbit at random treated by packet.
1.4 experimental animals are grouped and processing
Each case is included into trial drug group of the present invention respectively at random, and its dosage difference is divided into following four groups and sulphaguanidine tablet Control group is as follows:
It is control group to test 1 group, is not processed;
It is low dose group of the present invention to test 2 groups, 1/2 times of amount administration of clinical recommended dose (per kilogram of body weight 0.5g), is mixed Material, successive administration 5 days;
It is middle dose group of the present invention to test 3 groups, clinical recommended dose (per kilogram of body weight 1g) administration, spice, successive administration 5 My god;
It is high dose group of the present invention to test 4 groups, 2 times of amount administrations of clinical recommended dose (per kilogram of body weight 2g), spice, is connected Continuous administration 5 days;
It is sulphaguanidine tablet group to test 5 groups, is used to specifications:Spice, it is administered by per kilogram of body weight 0.2g, successive administration 5 days.
1.6 therapeutic effect decision methods
Clinical symptom disappearance, cut open inspection is without obvious pathological change.
Cure:Clinical symptom disappearance, defecation recover normal.
Effectively:Clinical symptom relief, excrement water sample mitigate.
It is invalid:Each clinical symptoms in criterion do not mitigate or aggravated.
1.7 statistical analysis
Examined through X2, test 2 groups of cure rates and total effective rate be substantially less than it is poor between other each group (P < 0.05) other each groups Different not notable (P > 0.05).
2 result of the tests
To the rabbit with gastroenteritis, give this Chinese medicine composition of various dose respectively, after spice, by with control group It is compared, the clinical symptoms of infected cattle substantially mitigate, and give milk horizontal recover.Low dose group therapeutic effect unobvious, middle dose group Therapeutic effect and output of milk recovery level all reached preferable requirement;Sulphaguanidine tablet control group therapeutic effect is ideal, But the output of milk recovers horizontal substantially not as the present invention.It the results are shown in Table 1.
The observation of curative effect of table 1
3 interpretations of result
Analyzed in terms of clinical symptoms, milk production treatment, cure rate three, the treatment of middle dose group and high dose group Positive effect is higher than other treatment group, wherein optimal with the prevention effect of middle dose group.Sulphaguanidine tablet control group has certain treatment Effect
4 conclusions
The present invention is administered by per kilogram of body weight 1g spices, rabbit gastroenteritis is treated in continuous 5 days, to being managed due to raising It is improper to manage, and has eaten mouldy, rotten and frost feed, has eaten the rabbit stomach and intestine caused by poisonous plant, agricultural chemicals or other poisonous substances by mistake Scorching significant effect.

Claims (2)

  1. A kind of 1. Chinese medicine composition for treating rabbit gastroenteritis, it is characterised in that:The component and its parts by weight of the Chinese medicine composition Counting ratio is:
  2. A kind of 2. preparation method of the Chinese medicine composition for the treatment of rabbit gastroenteritis as claimed in claim 1, it is characterised in that:Should The step of preparation method, is as follows:
    (1) root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and radix glycyrrhizae are weighed respectively according to weight proportion, is ground into powder End, and all pass through 80 mesh sieves respectively;
    (2) root of herbaceous peony, elscholtiza, Fructus Aurantii, silkworm excrement, the bark of official magnolia, cloves, ginger and the radix glycyrrhizae after being sieved in step (1) are put into blending tank In, it is sufficiently mixed uniformly, that is, the Chinese medicine composition finished product for the rabbit gastroenteritis that obtains medical treatment.
CN201711076387.9A 2017-11-06 2017-11-06 Treat Chinese medicine composition of rabbit gastroenteritis and preparation method thereof Pending CN107638556A (en)

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CN201711076387.9A CN107638556A (en) 2017-11-06 2017-11-06 Treat Chinese medicine composition of rabbit gastroenteritis and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201711076387.9A CN107638556A (en) 2017-11-06 2017-11-06 Treat Chinese medicine composition of rabbit gastroenteritis and preparation method thereof

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645274A (en) * 2013-11-21 2015-05-27 天津瑞贝特科技发展有限公司 Traditional Chinese medicine composition for treating cow acute gastroenteritis and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645274A (en) * 2013-11-21 2015-05-27 天津瑞贝特科技发展有限公司 Traditional Chinese medicine composition for treating cow acute gastroenteritis and preparation method thereof

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Application publication date: 20180130