CN107636011B - 特别在皮肤炎性疾病中用作药物的来自血纤蛋白原的分离的肽及其片段 - Google Patents

特别在皮肤炎性疾病中用作药物的来自血纤蛋白原的分离的肽及其片段 Download PDF

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CN107636011B
CN107636011B CN201680026130.XA CN201680026130A CN107636011B CN 107636011 B CN107636011 B CN 107636011B CN 201680026130 A CN201680026130 A CN 201680026130A CN 107636011 B CN107636011 B CN 107636011B
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propionibacterium acnes
fibrinogen
ala
lys
leu
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CN107636011A (zh
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N·迪潘
P·格兰斯
V·卡尔韦
J·瑞恩若
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INST GUSTAVE-ROUSSY
Paris Thackeray, University of
Western Dais Paris, University of
Centre National de la Recherche Scientifique CNRS
Assistance Publique Hopitaux de Paris APHP
Institut National de la Sante et de la Recherche Medicale INSERM
Sorbonne Universite
Universite Paris Cite
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INST GUSTAVE-ROUSSY
Centre National de la Recherche Scientifique CNRS
Universite Pierre et Marie Curie
Assistance Publique Hopitaux de Paris APHP
Institut National de la Sante et de la Recherche Medicale INSERM
Universite Paris Descartes
Universite Paris Sud
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201680026130.XA 2015-03-20 2016-03-21 特别在皮肤炎性疾病中用作药物的来自血纤蛋白原的分离的肽及其片段 Active CN107636011B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15305414.3 2015-03-20
EP15305414 2015-03-20
PCT/EP2016/056179 WO2016150926A1 (en) 2015-03-20 2016-03-21 Isolated peptides and fragments thereof from fibrinogen for use as drugs, particularly in skin inflammatory diseases

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CN107636011A CN107636011A (zh) 2018-01-26
CN107636011B true CN107636011B (zh) 2021-07-02

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US (1) US10323078B2 (https=)
EP (1) EP3270950B1 (https=)
JP (1) JP6840086B2 (https=)
CN (1) CN107636011B (https=)
AU (1) AU2016236297B2 (https=)
BR (1) BR112017020008A8 (https=)
CA (1) CA2979812C (https=)
DK (1) DK3270950T3 (https=)
ES (1) ES2880795T3 (https=)
WO (1) WO2016150926A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12502424B2 (en) 2023-05-05 2025-12-23 Sanofi Pasteur Inc. Compositions for use in treatment of acne
CN117304303B (zh) * 2023-07-14 2024-07-05 杭州恩和生物科技有限公司 纤连蛋白截短片段、组合物及用途

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012866A1 (en) * 1989-04-10 1990-11-01 Louisiana State University And Agricultural And Mechanical College Lytic peptides, use for growth, infection and cancer
CN1144539A (zh) * 1994-03-03 1997-03-05 酶遗传学公司 在转基因动物中生产纤维蛋白原
WO2003003988A2 (en) * 2001-07-06 2003-01-16 Oregon Health & Science University Peptides which modulate blood coagulation and methods of use thereof
CN102089322A (zh) * 2008-07-09 2011-06-08 普罗菲布瑞克斯公司 重组纤维蛋白原
JP2014505884A (ja) * 2011-02-02 2014-03-06 アカデミス ズィーケンハイス レイデン ハー.オー.デー.エン. エルユーエムセー 抗カルバミル化タンパク質抗体及び関節炎リスク
JP2014148541A (ja) * 2006-08-04 2014-08-21 Stb Ltd 創傷組織を治療するための固体包帯材の製造方法

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US6783961B1 (en) * 1999-02-26 2004-08-31 Genset S.A. Expressed sequence tags and encoded human proteins
CA2296792A1 (en) * 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
JP2003503425A (ja) * 1999-06-30 2003-01-28 リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 血栓性又は血栓塞栓性疾患のための診断的試験
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
CA2523358A1 (en) * 2003-04-23 2004-11-04 Hansa Medical Ab Method for identifying an anti-streptococcal agent and its use for treating streptococcal infections
BRPI0617688A2 (pt) * 2005-10-21 2011-06-07 Hoffmann La Roche método para expressão recombinante de um polipeptìdeo
US20130280820A1 (en) * 2005-12-16 2013-10-24 Schering Corporation Biomarkers for psoriasis
EP2361930A3 (en) * 2007-03-26 2011-10-26 Dako Denmark A/S Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases
CN101618211A (zh) * 2008-07-03 2010-01-06 珠海联邦制药股份有限公司 一种乙肝多肽疫苗及其应用
EP2352998A4 (en) 2008-11-07 2011-09-21 Centocor Ortho Biotech Inc MARKERS AND METHOD FOR THE STUDY AND TREATMENT OF LIGHT-SENSITIVELY LUPUS PATIENTS
EP4012714A1 (en) * 2010-03-23 2022-06-15 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990012866A1 (en) * 1989-04-10 1990-11-01 Louisiana State University And Agricultural And Mechanical College Lytic peptides, use for growth, infection and cancer
CN1144539A (zh) * 1994-03-03 1997-03-05 酶遗传学公司 在转基因动物中生产纤维蛋白原
WO2003003988A2 (en) * 2001-07-06 2003-01-16 Oregon Health & Science University Peptides which modulate blood coagulation and methods of use thereof
JP2014148541A (ja) * 2006-08-04 2014-08-21 Stb Ltd 創傷組織を治療するための固体包帯材の製造方法
CN102089322A (zh) * 2008-07-09 2011-06-08 普罗菲布瑞克斯公司 重组纤维蛋白原
JP2014505884A (ja) * 2011-02-02 2014-03-06 アカデミス ズィーケンハイス レイデン ハー.オー.デー.エン. エルユーエムセー 抗カルバミル化タンパク質抗体及び関節炎リスク

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
beta-fibrinogen, partial [Homo sapiens];Chung 等;《GenBank Database》;19960424;Accession No:AAA98115.1 *

Also Published As

Publication number Publication date
AU2016236297A1 (en) 2017-09-28
CA2979812C (en) 2023-08-29
EP3270950B1 (en) 2021-04-21
JP2018512844A (ja) 2018-05-24
JP6840086B2 (ja) 2021-03-10
AU2016236297B2 (en) 2020-07-23
CN107636011A (zh) 2018-01-26
EP3270950A1 (en) 2018-01-24
BR112017020008A2 (pt) 2018-06-19
CA2979812A1 (en) 2016-09-29
ES2880795T3 (es) 2021-11-25
US10323078B2 (en) 2019-06-18
DK3270950T3 (da) 2021-06-07
US20180105574A1 (en) 2018-04-19
WO2016150926A1 (en) 2016-09-29
BR112017020008A8 (pt) 2023-05-02

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