JP5101280B2 - ヘルペスウイルス感染の治療のためのペプチド - Google Patents
ヘルペスウイルス感染の治療のためのペプチド Download PDFInfo
- Publication number
- JP5101280B2 JP5101280B2 JP2007526458A JP2007526458A JP5101280B2 JP 5101280 B2 JP5101280 B2 JP 5101280B2 JP 2007526458 A JP2007526458 A JP 2007526458A JP 2007526458 A JP2007526458 A JP 2007526458A JP 5101280 B2 JP5101280 B2 JP 5101280B2
- Authority
- JP
- Japan
- Prior art keywords
- hervip
- hsv
- infection
- treatment
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/017—Hydrolysed proteins; Derivatives thereof from animals from blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Description
細胞アッセイを用いて、単純ヘルペスウイルスの感染率を決定する。HSV−2の阻害剤は、このアッセイにおいて感染率を低下させる。
Claims (3)
- アミノ酸配列
NH2−VCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH−COOH(配列番号1)
からなるペプチド又はその断片を含む、ウイルス性疾患治療用医薬組成物であって、前記断片が、
NH 2 −VCVLAHHFGKEF−COOH(配列番号2)、若しくは
NH 2 −CVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH−COOH(配列番号3)
であり、
前記ウイルス性疾患が単純ヘルペスウイルスを伴う感染により引き起こされる、医薬組成物。 - 前記ウイルス性疾患が細菌の不定着化を引き起こさない、請求項1に記載の医薬組成物。
- 注入、軟膏、錠剤、スプレー、「持続放出」カプセル及び類似調製物のために調合された製剤中での、及び/又は他の抗ウイルス治療剤との組み合わせによる、請求項1又は2に記載の医薬組成物。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60231304P | 2004-08-18 | 2004-08-18 | |
EP04019552 | 2004-08-18 | ||
US60/602,313 | 2004-08-18 | ||
EP04019552.1 | 2004-08-18 | ||
PCT/EP2005/054028 WO2006018431A2 (en) | 2004-08-18 | 2005-08-16 | Peptides for the treatment of herpes virus infections |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012186755A Division JP5568609B2 (ja) | 2004-08-18 | 2012-08-27 | ヘルペスウイルス感染の治療のためのペプチド |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008509969A JP2008509969A (ja) | 2008-04-03 |
JP5101280B2 true JP5101280B2 (ja) | 2012-12-19 |
Family
ID=34926208
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007526458A Expired - Fee Related JP5101280B2 (ja) | 2004-08-18 | 2005-08-16 | ヘルペスウイルス感染の治療のためのペプチド |
Country Status (7)
Country | Link |
---|---|
US (1) | US7741287B2 (ja) |
EP (1) | EP1778271B1 (ja) |
JP (1) | JP5101280B2 (ja) |
AT (1) | ATE411812T1 (ja) |
CA (1) | CA2558289C (ja) |
DK (1) | DK1778271T3 (ja) |
WO (1) | WO2006018431A2 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013028612A (ja) * | 2004-08-18 | 2013-02-07 | Ipf Pharmaceuticals Gmbh | ヘルペスウイルス感染の治療のためのペプチド |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1395137B1 (it) | 2009-08-05 | 2012-09-05 | Spider Biotech S R L | Nuovi peptidi antipatogeni |
ES2444299B1 (es) | 2012-08-23 | 2014-12-12 | Nutrición Técnica Deportiva, S.L. | Uso de un hidrolizado de caseina como agente antiherpético |
EP2789343A1 (en) * | 2013-04-11 | 2014-10-15 | Clinique La Prairie | Novel hemoglobin-derived peptide based pharmaceutical compositions |
JP6464507B2 (ja) * | 2014-12-24 | 2019-02-06 | 国立大学法人秋田大学 | 抗ウイルス剤、および抗菌剤 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS649997A (en) * | 1987-07-02 | 1989-01-13 | Toray Industries | Serine protease inhibitor |
US5922854A (en) * | 1991-06-14 | 1999-07-13 | Kumar; Ramesh | Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids |
US6610654B2 (en) * | 1993-03-31 | 2003-08-26 | Wellstat Therapeutics Corporation | Inhibitor of stem cell proliferation and uses thereof |
JPH08510997A (ja) * | 1993-03-31 | 1996-11-19 | プロ−ニューロン,インコーポレイテッド | 幹細胞増殖インヒビターおよびその使用 |
US5861483A (en) * | 1996-04-03 | 1999-01-19 | Pro-Neuron, Inc. | Inhibitor of stem cell proliferation and uses thereof |
AU3904497A (en) * | 1996-08-02 | 1998-02-25 | Somatogen, Inc. | Methods of controlling beta dimer formation in hemoglobin |
EA002242B1 (ru) * | 1997-10-08 | 2002-02-28 | ТЕРАГЕМ, Инк. | Пептиды млекопитающих для лечения микробной инфекции |
WO2001094386A2 (de) * | 2000-06-08 | 2001-12-13 | Ipf Pharmaceuticals Gmbh | Verfahren zur gewinnung und anwendung von antibiotisch wirksamen peptiden zur behandlung von infektionskrankheiten |
GB0125793D0 (en) * | 2001-10-26 | 2001-12-19 | Panzeri Ezio | Method |
-
2005
- 2005-08-16 DK DK05786951T patent/DK1778271T3/da active
- 2005-08-16 JP JP2007526458A patent/JP5101280B2/ja not_active Expired - Fee Related
- 2005-08-16 AT AT05786951T patent/ATE411812T1/de not_active IP Right Cessation
- 2005-08-16 WO PCT/EP2005/054028 patent/WO2006018431A2/en active Application Filing
- 2005-08-16 US US11/658,269 patent/US7741287B2/en active Active
- 2005-08-16 CA CA2558289A patent/CA2558289C/en not_active Expired - Fee Related
- 2005-08-16 EP EP05786951A patent/EP1778271B1/en not_active Not-in-force
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013028612A (ja) * | 2004-08-18 | 2013-02-07 | Ipf Pharmaceuticals Gmbh | ヘルペスウイルス感染の治療のためのペプチド |
Also Published As
Publication number | Publication date |
---|---|
CA2558289A1 (en) | 2006-02-23 |
CA2558289C (en) | 2018-05-15 |
US7741287B2 (en) | 2010-06-22 |
WO2006018431A2 (en) | 2006-02-23 |
EP1778271B1 (en) | 2008-10-22 |
DK1778271T3 (da) | 2009-02-16 |
US20080312144A1 (en) | 2008-12-18 |
ATE411812T1 (de) | 2008-11-15 |
WO2006018431A3 (en) | 2006-06-08 |
EP1778271A2 (en) | 2007-05-02 |
JP2008509969A (ja) | 2008-04-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2875826B1 (en) | Composition for preventing or treating sepsis | |
CN107735098B (zh) | 抗微生物疗法 | |
US9872885B2 (en) | Antimicrobial and anti-inflammatory peptides | |
CA2456477A1 (en) | Antimicrobial cationic peptides and formulations thereof | |
JP5101280B2 (ja) | ヘルペスウイルス感染の治療のためのペプチド | |
US20200384062A1 (en) | Use of inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation | |
KR101341210B1 (ko) | 신규한 항균 펩타이드 및 이의 용도 | |
US20170007662A2 (en) | Tetrapeptides Derived from Human C-X-C Chemokines Useful for Treatment of Various Skin Conditions | |
EP2125878B1 (en) | Short bio-active peptides for cellular and immunological modulation | |
EP3583934B1 (en) | Biocidal agent | |
JP5568609B2 (ja) | ヘルペスウイルス感染の治療のためのペプチド | |
US10857201B2 (en) | NNIF and nNIF-related peptides and related methods | |
CN112402592B (zh) | Spink7蛋白在制备促进过度炎症创面愈合的药物中的应用 | |
JP2017524000A (ja) | 腹膜炎の治療のための組成物 | |
US5698519A (en) | Polypeptide specifically inhibiting cathepsin L | |
EP3270950B1 (en) | Isolated peptides and fragments thereof from fibrinogen for use as drugs, particularly in skin inflammatory diseases | |
WO2002029082A1 (en) | Endothelial cell mitogen bioassay | |
US20210138033A1 (en) | nNIF AND nNIF-RELATED PEPTIDES AND RELATED METHODS | |
KR20220164450A (ko) | Agkistrodon piscivorus piscivorus 또는 Naja melanoleuca로부터 유래된 신규한 펩타이드, 및 이를 포함하는 베체트병 또는 류마티스 관절염의 치료용 조성물 | |
CN117229358A (zh) | 一种短肽抑制剂及其在制备治疗牙周病药物中的应用 | |
Bersani et al. | Rapid killing of actinomycin D-treated tumor cells-cytotoxicity of cell-free monocyte supernatants |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20080815 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120228 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20120522 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20120529 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120827 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20120918 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20120926 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20151005 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5101280 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |