CN107635579A - 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法 - Google Patents

非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法 Download PDF

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CN107635579A
CN107635579A CN201580024217.9A CN201580024217A CN107635579A CN 107635579 A CN107635579 A CN 107635579A CN 201580024217 A CN201580024217 A CN 201580024217A CN 107635579 A CN107635579 A CN 107635579A
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H·L·X·乌
F·奥索里奥
W·W·莱格雷德
A·K·帕特奈克
马方瑞
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Knob Tyke Wen Tusi Co
University of Illinois System
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Knob Tyke Wen Tusi Co
University of Illinois System
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
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  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580024217.9A 2014-03-21 2015-03-25 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法 Pending CN107635579A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461968465P 2014-03-21 2014-03-21
PCT/IB2015/052214 WO2015140774A1 (en) 2014-03-21 2015-03-25 A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using

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Publication Number Publication Date
CN107635579A true CN107635579A (zh) 2018-01-26

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CN201580024217.9A Pending CN107635579A (zh) 2014-03-21 2015-03-25 非天然发生的猪生殖和呼吸综合征病毒(prrsv)和使用方法

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US (3) US10072046B2 (enExample)
EP (1) EP3119429A4 (enExample)
JP (1) JP6538071B2 (enExample)
KR (1) KR20170002393A (enExample)
CN (1) CN107635579A (enExample)
CA (1) CA2943478A1 (enExample)
HK (1) HK1247128A1 (enExample)
MX (1) MX378873B (enExample)
PH (2) PH12016501854B1 (enExample)
RU (1) RU2687150C2 (enExample)
WO (1) WO2015140774A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118791578A (zh) * 2024-07-29 2024-10-18 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 猪繁殖与呼吸综合征病毒nsp12蛋白的抗原表位、单克隆抗体及应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015140774A1 (en) 2014-03-21 2015-09-24 Nutech Ventures A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using
TWI652347B (zh) * 2016-02-18 2019-03-01 美商益農美國公司 豬繁殖與呼吸綜合症疫苗病毒
US20240189418A1 (en) * 2021-03-31 2024-06-13 The Industry & Academic Cooperation In Chungnam National University (Iac) Virus vaccine based on virus surface engineering providing increased immunity

Citations (2)

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CN101300363A (zh) * 2005-08-30 2008-11-05 内布拉斯加大学董事会 用于用具有改善的免疫原性的prrsv抗原免疫接种动物的方法和组合物
US20110104201A1 (en) * 1999-04-22 2011-05-05 Mengeling William L Porcine Reproductive and Respiratory Syndrome Vaccine Based on Isolate JA-142

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US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US6380376B1 (en) * 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
SK286063B6 (sk) 1997-05-06 2008-02-05 Boehringer Ingelheim Vetmedica Gmbh Peptid vyvolávajúci tvorbu protilátok, protilátkareaktívna s týmto peptidom a diagnostická súpravaobsahujúca peptid a protilátku
HUP0204176A3 (en) * 2000-01-26 2003-12-29 Boehringer Ingelheim Vetmed Recombinant attenuation of prrsv
US20020012670A1 (en) 2000-01-26 2002-01-31 Knut Elbers Recombinant attenuation of porcine reproductive and respiratory syndrome (PRRSV)
CN101495138B (zh) * 2005-11-29 2014-01-08 衣阿华州立大学研究基金公司 猪繁殖与呼吸综合征病毒(prrsv)的保护性抗原决定子的鉴定及其用途
UA108902C2 (uk) * 2010-11-10 2015-06-25 Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування
US9187731B2 (en) * 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
EP2737058A1 (en) * 2011-07-29 2014-06-04 Boehringer Ingelheim Vetmedica GmbH INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
EP2620446A1 (en) * 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
WO2015140774A1 (en) * 2014-03-21 2015-09-24 Nutech Ventures A non-naturally occuring porcine reproductive and respiratory syndrome virus (prrsv) and methods of using

Patent Citations (2)

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US20110104201A1 (en) * 1999-04-22 2011-05-05 Mengeling William L Porcine Reproductive and Respiratory Syndrome Vaccine Based on Isolate JA-142
CN101300363A (zh) * 2005-08-30 2008-11-05 内布拉斯加大学董事会 用于用具有改善的免疫原性的prrsv抗原免疫接种动物的方法和组合物

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HIEP L. X. VU: "A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection", 《JOURNAL OF VIROLOGY》 *
TONG-QING AN等: "Identification of a Novel B Cell Epitope on the Nucleocapsid Protein of Porcine Reproductive and Respiratory Syndrome Virus by Phage Display", 《VIRUS GENES》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118791578A (zh) * 2024-07-29 2024-10-18 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 猪繁殖与呼吸综合征病毒nsp12蛋白的抗原表位、单克隆抗体及应用

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Publication number Publication date
US10072046B2 (en) 2018-09-11
US20200331970A1 (en) 2020-10-22
JP6538071B2 (ja) 2019-07-03
HK1247128A1 (zh) 2018-09-21
PH12020550204A1 (en) 2021-01-11
KR20170002393A (ko) 2017-01-06
JP2017510276A (ja) 2017-04-13
EP3119429A4 (en) 2018-04-04
CA2943478A1 (en) 2015-09-24
RU2016141287A3 (enExample) 2018-06-07
US20190048042A1 (en) 2019-02-14
US11136355B2 (en) 2021-10-05
MX2016012276A (es) 2017-06-12
RU2687150C2 (ru) 2019-05-07
WO2015140774A1 (en) 2015-09-24
PH12016501854A1 (en) 2017-01-09
MX378873B (es) 2025-03-11
EP3119429A1 (en) 2017-01-25
US10738088B2 (en) 2020-08-11
RU2016141287A (ru) 2018-04-26
US20170198016A1 (en) 2017-07-13
PH12016501854B1 (en) 2017-01-09

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