CN107596247B - Mongolian medicine for treating lung disease and its preparing process - Google Patents

Mongolian medicine for treating lung disease and its preparing process Download PDF

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CN107596247B
CN107596247B CN201710988654.3A CN201710988654A CN107596247B CN 107596247 B CN107596247 B CN 107596247B CN 201710988654 A CN201710988654 A CN 201710988654A CN 107596247 B CN107596247 B CN 107596247B
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AFFILIATED HOSPITAL OF INNER MONGOLIA UNIVERSITY FOR NATIONALITIES
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Abstract

The invention relates to a medicine and a manufacturing process thereof, in particular to a Mongolian medicine for treating lung diseases and a manufacturing process thereof, which is characterized in that: the Mongolian medicine comprises the following raw material medicines in parts by weight: 2-18 parts of copper derivatives, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 1-3 parts of linaloe oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of tectoridin, 1-3 parts of myrobalan tannic acid, 16-24 parts of cardamon, 8-12 parts of radix glehniae, 8-12 parts of black spruce, 8-12 parts of calculus bovis factitious and 1-2 parts of musk artificate. The invention has the beneficial effects that: the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity, benefiting lung and relieving cough and reducing sputum, has obvious curative effects on cough and excessive phlegm, chest and lung abscess, tuberculosis and even lung cancer and the like, has low toxic and side effects, wide applicable population range, is convenient to take, is convenient to digest and absorb, has quick response, and is expected to become a typical medicine for treating lung diseases.

Description

Mongolian medicine for treating lung disease and its preparing process
Technical Field
The present invention relates to a medicine for curing pulmonary diseases and its preparation method.
Background
The lung diseases mainly refer to lung diseases such as cough with excessive phlegm, chest and lung abscess, pulmonary tuberculosis and even lung cancer. Modern medicine refers to lung inflammation, pulmonary tuberculosis, space occupying lesion and the like, and Mongolian medicine has rich treatment experience for the diseases and has various effective Mongolian medicine formulas. However, the Mongolian medicines are mostly spread to folk in the form of proved prescriptions, some Mongolian medicines are already endangered and lost, some Mongolian medicines are completely inexorable after being repeatedly encrypted, and some Mongolian medicines are deficient in resources or forbidden, so that the compatibility is inconsistent, the mechanism is unknown, the efficacy is unstable, and the clinical application is limited. The Mongolian medicine is prepared by the old processing method, is mostly prepared into powder in an unprocessed mode, has large dosage, is difficult to take, and has toxic and side effects. Therefore, the research and arrangement of the traditional Mongolian medicine for treating the lung diseases are urgently needed, and a Mongolian medicine formula which has the advantages of definite curative effect, no toxic or side effect, sufficient medicine source, advanced preparation method and convenient taking is found.
Disclosure of Invention
The invention aims to find a Mongolian medicine which has obvious curative effect on lung lesions such as cough, excessive phlegm, chest and lung abscess, tuberculosis and even lung cancer, has low toxic and side effect or no fog and side effect, sufficient medicine source, advanced preparation method and convenient taking and a preparation process thereof.
The above purpose is realized by the following technical scheme: a Mongolian medicine for treating lung diseases is characterized in that: the Mongolian medicine for treating the lung diseases comprises the following raw material medicines in parts by weight: 2-18 parts of copper derivatives, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 1-3 parts of linaloe oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of tectoridin, 1-3 parts of myrobalan tannic acid, 16-24 parts of cardamon, 8-12 parts of radix glehniae, 8-12 parts of black spruce, 8-12 parts of calculus bovis factitious and 1-2 parts of musk artificate.
The copper derivative 2-18 parts is 12-18 parts of copper ash (prepared), 2-4 parts of verdigris or 2-3 parts of chalcanthite.
2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate and 2-5 parts of amino acid are replaced by 40-60 parts of cloven-hoof animal horn.
40-60 parts of cloven hoof animal horn comprises one or two or more of buffalo horn concentrated powder 8-12 parts, antelope horn 8-12 parts, antler 8-12 parts, ox horn 18-22 parts and antler 8-12 parts.
The cardamom 16-24 parts are cardamom 8-12 parts and nutmeg 8-12 parts.
The raw material medicines of sandalwood oil, clove oil, linaloe oil, carthamin, dimethoxycoumarin, tectoridin and myrobalan tannic acid are respectively replaced by the following raw material medicines: the sandalwood oil is replaced by 8-12 parts of white sandalwood and 8-12 parts of purple sandalwood; the clove oil is replaced by 8-12 parts of clove; the tectoridin is replaced by 8-12 parts of iris, 8-12 parts of blackberry lily, 8-12 parts of kudzu vine flower or 8-12 parts of iris japonica; 8-12 parts of gypsum are used for replacing the calcium sulfate; 8-12 parts of artemisia scoparia or 8-12 parts of oriental wormwood are used for replacing the dimethoxycoumarin; the myrobalan tannic acid is replaced by 8-12 parts of myrobalan; 8-12 parts of agilawood is used for replacing the linaloe oil; the carthamin is replaced by 8-12 parts of safflower.
The raw material medicines comprise 8-12 parts of tsaoko amomum fruits, 8-12 parts of bistort rhizome, 8-12 parts of radix ophiopogonis, 8-12 parts of hosta plantaginea flowers and 8-12 parts of cichorium victorioides.
The cornu Saigae Tataricae, cornu Cervi, and cornu bovis Seu Bubali are prepared by soaking in 75% ethanol or steam sterilizing, and pulverizing into fine powder. Adding 10 times of water by weight, decocting for two times, each time for 7-10 hours, supplementing distilled water at any time in the decocting process, mixing the decoctions, filtering, concentrating the filtrate to 1-5% of the original weight, drying at the temperature of below 80 ℃, crushing into fine powder, and sieving to obtain the traditional Chinese medicine composition. Mixing with other raw materials, and making into pill, powder, unguent or capsule.
The cardamom, the coastal glehnia root, the black cloud incense, the white sandalwood, the clove, the iris, the blackberry lily, the kudzu flower, the iris, the artemisia scoparia, the oriental wormwood, the myrobalan, the agilawood, the safflower, the tsaoko amomum fruit, the bistort rhizome, the dwarf lilyturf tuber, the hosta plantain flower and the cichorium victorium L.var.vicornum L.var.benth are all ground into powder, sieved by a sieve with more than 60 meshes, mixed with other raw materials and prepared into.
Pulverizing fructus Amomi rotundus, radix Glehniae, HEIYUNXIANG, lignum Santali albi, lignum Pterocarpi Indici, flos Caryophylli, rhizoma Iridis Tectori, rhizoma Belamcandae, flos Puerariae Lobatae, flos Oroxyli, herba Artemisiae Scopariae, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hostae Plantagineae, and herba Cichorii, sieving with 80 mesh sieve, mixing, extracting with 70% ethanol for 30-60 min, and recovering ethanol under reduced pressure; extracting with ethyl acetate for 30-60 min, recovering solvent, concentrating, pulverizing, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, ointment or capsule.
The invention has the beneficial effects that: the traditional Chinese medicine composition has the effects of clearing heat and removing toxicity, benefiting lung and relieving cough and reducing sputum, has obvious curative effects on cough and excessive phlegm, chest and lung abscess, tuberculosis and even lung cancer and the like, has low toxic and side effects, wide applicable population range, is convenient to take, is convenient to digest and absorb, has quick response, and is expected to become a typical medicine for treating lung diseases.
Detailed Description
The first embodiment:
the Mongolian medicine for treating the lung diseases is developed and comprises the following raw material medicines in parts by weight: 2-18 parts of copper derivatives, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 1-3 parts of linaloe oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of tectoridin, 1-3 parts of myrobalan tannic acid, 16-24 parts of cardamon, 8-12 parts of radix glehniae, 8-12 parts of black spruce, 8-12 parts of calculus bovis factitious and 1-2 parts of musk artificate.
Pulverizing fructus Amomi rotundus, radix Glehniae, and HEIYUNXIANG into powder, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, ointment or capsule.
The taking method comprises the following steps: the adult takes the medicine 1.5-2 g/time and 2-3 times daily.
The copper derivative herein is a broad-sense oxide of metallic copper, and various fine powder-like products are available. The copper ware is traditional Mongolian tableware, the copper element is one of indispensable nutrient substances of human bodies, and the copper has a treatment effect on various diseases when being used as a medicine, and particularly has an exact curative effect on lung diseases. The copper drugs are prepared in many ways, and the examples recommend copper ash (made) and also can adopt verdigris or chalcanthite.
The copper ash is a traditional Mongolian medicinal material, is mostly a thin layer which falls off due to high-temperature forging in the manufacturing process of a copper ware, and can also be applied after calcining red metal copper, smashing into a polar slice or filing, boiling sea buckthorn soup, drying, grinding together with sulfur, borax and sesame, and calcining. The custom of the processed products is called copper ash which is also called red copper ash, and Mongolia is named hucho sound and turnera element. The copper ash has the functions of clearing heat from lung and liver, and can be used for treating lung heat, liver abscess, pulmonary tuberculosis, cough with pus, hemoptysis, etc. The present example uses 12-18 parts as the medicine, and the clinical curative effect is significant.
The copper green is green basic copper carbonate generated on the surface of copper which is oxidized after being wetted in the air. In ancient times, verdigris is rust of copper, and can be sprayed on copper with vinegar to accelerate the generation of green rust, and scraped to obtain the product. Verdigris is bitter, sour, astringent and cold in flavor. Is toxic. Has effects of removing toxic substance, removing necrotic tissue, and killing parasite. It is used as an external medicine for treating nasal , erosion of eyelid, sore and ulcer, stubborn dermatitis, etc. because it is toxic. The oral administration is usually combined with corresponding prescriptions to treat diseases such as wind-phlegm, sudden syncope, blood, qi and heart pain, etc., and the dosage for an adult is limited within 5g each time. The maximum proportion of the medicine is only 8 percent when 2-4 parts are taken, is 160 mg/time according to the dosage of 2 g/time, belongs to safe dosage and is suitable for patients taking medicines for a short time.
Chalcanthitum, English name Copper (II) sulfate pentahydrate, molecular formula CUSO 4.5H 2O, Chinese name copper sulfate pentahydrate, Chinese name blue vitriol, Chalcanthitum, copperas, copper sulfate pentahydrate (medicinal), copper sulfate (feed grade). Belongs to emetics in traditional Chinese medicines. Cold in nature; sour and pungent in flavor; it enters liver and gallbladder meridians. Has the functions of promoting expectoration, removing toxic substance, eliminating dampness, eliminating putrefaction and eliminating sore. It can be used for treating wind-phlegm obstruction, pharyngitis, epilepsy, improper intake of toxic substances, conjunctival congestion, aphtha, and ulcerative gingivitis. It is toxic, so it can cause intoxication by mistake or overdose. The dosage for adult is less than 300mg per time. The maximum proportion of the chalcanthite used in the example is only 6 percent, calculated according to the dose of 2 g/time, the dose is 120 mg/time, the pharmaceutical composition belongs to a safe dose, and is suitable for patients taking medicine for a short time.
Calcium carbonate, molecular formula: CaCO 3. The light calcium carbonate can be used as a leavening agent, a flour treating agent, an anticaking agent, an acidity regulator, a nutrition enhancer, a curing agent and the like. The said gum can be used for various foods and gum bases which need to be added with puffing agent according to GMP. Can also be used as flour improver, and the maximum usage amount is 0.03%; 7.5-18 g/kg of milk powder; 4-20 g/kg of soymilk powder and soybean powder; 0.4-3.4 g/kg of soft drink; 6-8 g/kg of lotus root starch; 2-7 g/kg of the instant breakfast cereal product. FDA (184.1192,2000) is not restricted, but is in GMP. When the product is used as a leavening agent, the product is often used together with other varieties, and the leavening agent obtained by compounding the product with sodium bicarbonate, alum and the like slowly releases carbon dioxide when heated, so that food can generate uniform and fine leavening bodies, and the quality of cakes, bread and biscuits can be improved. In addition, the calcium carbonate has the function of strengthening calcium, and the smaller the calcium carbonate particles, the easier the calcium carbonate particles are to absorb. In Japan, light calcium carbonate is used as a leavening agent, and is generally used in an amount of 1% in foods. It can also be used as feed nutrition enhancer. Calcium carbonate is the main component of the calcite of the mongolian medicine and has the effects of clearing away the heat of the body, stopping vomiting, stopping diarrhea, helping digestion, detoxifying, breaking the stuffiness, healing wound, setting bone and regulating vitality and the like.
Calcium phosphate, tribasic, formula (Ca3(PO4)2), is insoluble in ethanol and acetone, slightly soluble in water, and readily soluble in dilute hydrochloric and nitric acids. Can be used as anticaking agent, acidity regulator, nutritional supplement, flavoring agent, stabilizer, and water retention agent. Are used in the food industry as anticaking agents, acidity regulators, nutritional supplements, flavoring agents, stabilizers, moisture retention agents. The food additive use health standard (GB2760-2011) of China stipulates: the calcium phosphate can be used for wheat flour, and the maximum usage amount is 0.03 g/kg; 8.0g/kg of solid beverage; 2.0g/kg of fried potato chips. Can be used as moisture retention agent in flour. FAO/WHO regulations: can be used as anticaking agent for glucose powder and sucrose powder, with maximum dosage of 15g/kg (alone or in combination with other anticaking agent, without starch); milk powder, cream powder, 5g/kg (alone or in combination with other stabilizers, on an anhydrous basis); for vending machines, 10g/kg of milk powder, 1g/kg of cream powder (alone or in combination with other anti-caking agents), soup and soup, 15mg/kg (alone or in combination with stearates and silica, referred to as dehydrated product); cocoa powder and sugary cocoa powder, 10g/kg (alone or in combination with other anti-caking agents, sugary cocoa powder is used only in vending machines). The stabilizer can be used in light condensed milk, sweetened condensed milk and cream, and the dosage is 2g/kg (single use) and 3g/kg (combined with other stabilizer), all based on anhydrous substance. The amount used for processing the cheese was 9g/kg (total phosphate, in terms of phosphorus). The product can be used as calcium element enhancer for cookies and bread, etc., and has dosage of 3g/kg for cereal powder and 20g/kg for solid beverage, both in terms of calcium element. The calcium phosphate is the main component of animal bones of deer, cattle, sheep, pig and the like which are traditional Chinese medicines for Mongolian medicine, and has the effects of detoxifying, soothing the nerves, resisting convulsion, strengthening the body and the like.
The hydrous calcium sulfate (CaSO4 & 2H 2O) is cool in nature and has the effects of clearing heat and removing toxicity. It has effects in clearing heart and lung, relieving dysphoria, clearing away stagnated heat, relieving dryness and thirst, relieving mania and cough, eliminating hot sweat, eliminating phlegm, stopping epistaxis, regulating aphtha, relieving pharyngalgia, promoting lactation, relieving mammary abscess, clearing pathogenic fire, and treating incised wound. For headache, fever, blurred vision, nebula, toothache, insecticiding and diuresis.
The amino acid (amino acid) is a general name of a class of organic compounds containing amino groups and carboxyl groups, and the basic constituent unit of macromolecular protein is a basic substance of protein required by animal nutrition. The amino acids include various amino acids, such as lysine, alanine, arginine, aspartic acid, cystine, leucine, proline, tyrosine, histidine, and valine.
Sandalwood Oil, the English name of Sandalwood Oil, Santallum Album L, is volatile Oil obtained by distilling heartwood of Santalum album of Santalaceae, wherein the volatile Oil contains more than 90% of santalenol A and beta-santalenol (alpha-, beta-Santalol), has strong antibacterial effect, and has been used as a urethral disinfectant. The traditional Chinese medicine is bitter in taste and warm in nature, enters stomach and kidney channels, and has the effects of lowering adverse qi, harmonizing stomach, promoting qi circulation, relieving pain, stopping whitish and turbid, and eliminating heat and swelling. It is commonly used to treat hiccup, vomiting, epigastric pain, lumbago, kidney pain, pain in the heart and abdomen. Modern researches find that sandalwood oil can inhibit the growth of staphylococcus aureus in urinary tract and improve the symptom of difficult urination. Has effect in inhibiting dysentery bacillus and avian type tubercle bacillus.
The oleum Caryophylli is volatile oil obtained by distilling dried flower bud (flos Caryophylli) of Myrtaceae family (Eugenia caryophyllata) of dicotyledonous plant, and mainly contains Eugenol, acetosyringol, B-Caryophyllene (B-Caryophyllene), methyl n-amyl ketone, methyl salicylate, humulene (Humulen), benzaldehyde, benzyl alcohol, m-methoxybenzaldehyde, benzyl acetate, piperonyl (Chavicol), a-Ylangene (a-Ylangene), etc. The herbs are sweet and pungent in flavor, have strong heat in nature and enter stomach and kidney meridians, so they have the actions of warming middle energizer, warming kidney and lowering adverse qi. It is indicated for hiccup, vomiting, regurgitation, dysentery, psychroalgia, bubo, hernia, tinea, etc. It can be used for treating skin wound such as sore, carbuncle, furuncle, etc., and has repercussive, antiinflammatory, and healing promoting effects.
Linaloe oil, volatile oil contained in lignum Aquilariae Resinatum, including benzyl acetone, p-methoxybenzyl acetone, hydrogenated cinnamic acid, p-methoxyhydrogenated cinnamic acid, linalool (agar-spirol), linalool (agar), Agarofuran (Agarofuran), dihydroagarofuran, 4-hydroxy dihydroagarofuran, 3, 4-dihydroxy dihydroagarofuran, noragarofuran (Nor-ketoagana-rofuran), etc. The research finds that the linaloe oil is the main active ingredient of the agilawood, and has obvious curative effects on cough, excessive phlegm, chest and lung abscess, pulmonary tuberculosis, even lung cancer and other lung diseases besides the original drug effect of the agilawood.
Carthamin (Chinese medicine II, lyophilized preparation) is a water-soluble flavonoid extracted from Carthami flos, and pharmacodynamics literature reports that Carthami flos has effects of reducing coronary artery resistance, increasing coronary artery flow and nourishing myocardium. Carthamin can reduce range and degree of experimental myocardial infarction of rabbit, and improve injury and necrotic electrocardiogram change. Pharmacodynamic studies show that carthamin 7-28mg/kg can remarkably inhibit the ST segment increase of an epicardium electrogram caused by left coronary artery ligation of dogs, reduce the release of serum acid kinase and reduce the myocardial infarction area. Carthamin has obvious effects on experimental thrombosis and platelet aggregation of rats.
Dimethoxycoumarin, English name Scoparone, has the functions of relieving asthma, relieving cough and eliminating phlegm. Is suitable for treating bronchial asthma and asthmatic bronchitis, especially senile bronchial asthma; it is also suitable for coronary atherosclerotic heart disease (coronary heart disease), angina pectoris and arrhythmia.
Tectoridin, an english name Tetoridin, molecular formula C22H22O11It can clear heat-toxicity and relieve swelling and pain, and is commonly indicated for swollen and sore throat, constipation, obstruction of throat, cough and asthma, abdominal pain due to wind-heat or excessive phlegm-heatHydrocele, blackening skin, swelling and stabbing scrotal hernia, and acute mastitis.
Myrobalan Tannic acid, english name Tannic acid, chinese alias: chebular tannic acid, chebular tannins, melitensic acid, chebularin, of formula C76H52O46, which comprises chebulariac acid (Chebulagic acid), chebulanic acid (Chebulinic acid), procymic acid (Terchebin), Corilagin (Corilagin), glucogallotannin (glucagollin), gallic acid (Ellagic acid), 1,3, 6-tri-galloylglucose and 1,2,3,4, 6-pentagalloylglucose, further comprises shikimic acid, dehydroshikimic acid, quinic acid, arabinose, fructose, glucose, sucrose, rhamnose and amino acids, sennoside A (sennoside A), chebularin (Chebulin), Tannase (Tannase), polyphenoloxidase (polyphenoloxidase), peroxidase, ascorbate and the like. Has the functions of astringing lung, astringing intestine, descending qi, etc. It is indicated for chronic cough, aphonia, chronic diarrhea, chronic dysentery, rectocele, hematochezia, metrorrhagia, leukorrhagia, spermatorrhea and frequent micturition.
Cardamom, english name Jave Amonum front, latin name: alpinia katsumadai Hayat [ Languas katsumadai (Hayata) Merr ], and there are many species such as Alpinia katsumadai, Amomum cardamomum, and Alpinia galanga, and similar species such as Myristica fragrans. In this example, cardamom and nutmeg are recommended. The fructus Amomi rotundus is dry mature fruit of Amomum cardamomum Amomum kravanh Pierre ex Gagnep or Amomum cardamomum Amomum compactum Soland ex Maton of Zingiberaceae. Nature and taste: pungent and hot. It enters lung, spleen and stomach meridians. The functions are as follows: dispel cold and dry dampness, relieve alcoholism, resolve dampness and relieve stuffiness, promote qi circulation and warm the middle warmer, stimulate appetite and promote digestion. The main treatment is as follows: damp turbidity obstructing the middle energizer, poor appetite, initial damp-warm sensation, chest distress, no hunger, vomiting due to cold-dampness, distending pain in chest and abdomen, and indigestion. Myristica fragrans, known as Myristica fragrans, is the kernel of a plant of the genus Myristica, which is used for diarrhea due to deficiency, cold dysentery, abdominal cold pain, vomiting, etc., and can be used as a parasite repellent for external use to treat rheumatalgia, etc.
Radix Glehniae is obtained from Eucheuma Coralliacea (Glehnia lit-toralis F. Schmidt ex Miq.) of Umbelliferae by root. Radix Glehniae, radix Adenophorae, radix Glehniae, radix Codonopsis Lanceolatae, radix Glehniae, and radix Glehniae. Contains imperatorin, psoralen, bergapten, angelolide-7-0-beta-gentiobioside, alkaloid, starch, and trace amount of volatile oil. The radix glehniae is sweet in taste, is a common clinical yin-nourishing medicine, and has the effects of nourishing yin, clearing away the lung-heat, eliminating phlegm and relieving cough. It can be used for treating dry cough due to lung dryness, body fluid impairment due to fever, and thirst.
The herba Blumeae Laciniatae is dried Resin of Commiphora corniphora muakulis (Guggulum) of Burseraceae, and contains stearic acid, stigmast-4-ene-3, 6-dione, beta-sitosterol, 6 beta-hydroxystilgmast-4-ene-3-one, 2 beta, 20(s) -dihydrodammar-24-ene-3-one, daucosterol, and isolariciresinol. The composition has bitter taste, cold nature, and fragrant smell, has effects of relieving swelling and pain, and healing wound, and can be used for treating measles, smallpox, scarlet fever, anthrax, hemiplegia, liver heat, fracture, and brain pain. Modern pharmacological studies prove that the black cloud incense can reduce cholesterol, phospholipid and triglyceride in serum and has thyroid activation effect, and the components in the black cloud incense have obvious anti-inflammatory, antibacterial and anti-tumor effects and the like.
The artificial bezoar is an artificial product of natural bezoar, and the bezoar Bos taurus domesticus Gmelin is also called as XIHUANG, rhinoceros flavus and semen Pharbitidis, and is gallstone of liver of bovine of Bos of Calidae of Heteroclada. It contains cholic acid 5-11%, deoxycholic acid 2%, chenodeoxycholic acid 0.6-1.7% and its salts, bilirubin and its calcium salt, cholesterol, ergosterol, lecithin, fatty acid, vitamin D, water-soluble peptide SMC, and copper, iron, magnesium, zinc, etc. Australia produced bezoar contains a plurality of amino acids such as carotenoid, alanine, glycine, taurine (taurine), aspartic acid, arginine, leucine, methionine and the like. The traditional Chinese medicine considers that the bezoar gas is fragrant, slightly bitter and then sweet in taste and cool in nature. Can be used for clearing away heat and toxic materials and arresting convulsion. It is used orally for high fever, coma, mania, infantile convulsion, and externally for sore throat, aphtha, carbuncle, and uremia.
Artificial musk is an artificial synthetic product of natural musk. Musk, Moschus, Moschus, fructus Amomi, and fructus Citri Sarcodactylis. Is dried secretion of Moschus berezovski Flerov. maschus M. sifacus Przewalski or original muskiness M. mosciferus L. male sachet. Contains Muscone (Muscone), Normuscone (Normuscone), Muscol (Muscol), musk pyran (Mus-copyran), musk pyridine (muscopyradine), hydroxymusk pyridine-A (hydroxymusk pyridine A), hydroxymusk pyridine-B (hydroxymusk pyridine B), 3-methylcyclotridecanone (3-Me-methylcyclotridecane-1-one), cyclotetradecanone (cyclotetradecane-can-1-one), etc. Also contains 11 kinds of androstane derivatives such as Cholest-4-ene-3-one, cholesterol and its esters, Testosterone (Testosterone), estriol (Estradiol), 5 alpha-androstane-3, 17-dione (5 alpha-Androstan-3, 17-dione). The musk contains about 25% of protein, a peptide active substance with the molecular weight of about 1000 is found in the musk, a polypeptide with the molecular weight of about 5000-6000 is separated, an alcohol solution of the polypeptide contains 4 free amino acids, namely arginine, proline, glycine and alanine, the alcohol solution is extracted by acetone, methanol and water, and the amino acid analysis after hydrolysis shows that: the content of amino acids in the methanol extract is highest, wherein the content of aspartic acid, serine, cystine and the like is highest; the acetone extract has high content of glutamic acid, valine, histidine and glycine. The Moschus may also contain potassium, sodium, calcium, magnesium, aluminum, lead, chlorine, sulfate, phosphate, ammonium carbonate, Allantoin (alantoin), urea, cellulose, etc. The musk ketone is an important effective component, the content of the musk ketone accounts for 1.58-1.84 percent of that in the natural musk meat and 0.90-3.08 percent of that in the natural musk hair shell, and the musk ketone can be artificially synthesized at present. Pungent and warm in nature and flavor. Enter heart, spleen and liver meridians. Has effects in inducing resuscitation, promoting blood circulation, resolving hard mass, and relieving pain. The book Ben Cao mu records that the medicine has the functions of dredging orifices, dredging channels and collaterals, penetrating muscle and bone, relieving alcoholism, eliminating food stagnation of melons and fruits, and treating apoplexy, middle warmer energy, nausea, phlegm syncope and abdominal mass. The mask musk deer moving and scurrying can unblock the obstruction of orifices and open the obstruction of meridians and collaterals, and people with wind, qi, blood, pain, epilepsy, abdominal mass, obstruction of meridians and orifices are not suitable for guiding the opening of orifices. Not unavailable but not too far past the ear ". It is indicated for its broad action but mainly used for guidance.
Brief description of the experimental examples:
since 2013, a large number of clinical trials are carried out on the basis that toxic and side effects are not found through toxicological experiments, and satisfactory curative effects are obtained. The following experimental cases are exemplified for only one set of recipes:
12-18 parts of copper ash, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 2-5 parts of dimethoxycoumarin, 0.1-0.8 part of tectoridin, 16-24 parts of cardamom, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of black cloud incense, 1-3 parts of myrobalan tannic acid, 8-12 parts of calculus bovis artifactus and 1-2 parts of artificial musk.
Wherein, the amomum cardamomum, the nutmeg, the radix glehniae and the black cloud incense are ground into powder, sieved by a sieve with more than 60 meshes and mixed with other raw material medicines to obtain the traditional Chinese medicine composition.
The taking method comprises the following steps: the adult takes the medicine 1.5-2 g/time and 2-3 times daily. One week is a treatment course.
The disease condition is relieved effectively, the symptom disappears, the relapse is not found in 3 months, the disease is cured, and the disease is not relieved after the medicine is taken for two weeks. The types, the number and the treatment conditions of the lung lesions are as follows:
the disease condition is relieved effectively, the symptom disappears, the relapse is not found in 3 months, the disease is cured, and the disease is not relieved after the medicine is taken for two weeks. The types, the number and the treatment conditions of the lung lesions are as follows:
Figure 152020DEST_PATH_IMAGE002
effective rate = (effective number + cured number)/total number X100%, and cure rate = cured number/total number X100%.
Experiments prove that: the medicine has better treatment effect on lung pathological changes such as cough, excessive phlegm, chest and lung abscess, tuberculosis, lung cancer and the like, and has the obvious advantages of small dosage, convenient taking, low cost, low toxic and side effect and the like compared with the conventional medicine.
The second embodiment:
in the first embodiment, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate and 2-5 parts of amino acid are replaced by 1-38 parts of artiodactyl horn. The following formula is formed:
12-18 parts of copper ash, 1-38 parts of artiodactyla angustifolia, 2-5 parts of hydrous calcium sulfate, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 2-5 parts of dimethoxycoumarin, 0.1-0.8 part of tectoridin, 1-3 parts of Chinese eaglewood oil, 1-3 parts of carthamin, 16-24 parts of cardamom, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of black yunxiang, 1-3 parts of myrobalam tannic acid, 8-12 parts of calculus bovis artifactus and 1-2 parts of musk artifactus.
The artiodactyl animal horn 1-38 parts comprises one or two or more of buffalo horn concentrated powder 8-12 parts, antelope horn 1-3 parts, antler 8-12 parts, ox horn 8-12 parts and antler 8-12 parts.
Buffalo Horn, the english name Buffalo Horn, the latin name Cornu Bubali, the dihedral of a bovine animal. Cornu bubali contains cholesterol (cholestroolo), cardiotonic ingredients, peptides, horn fibers; and serine (serine), glycine (glycine), alanine (alanine), lysine (lysine), histidine (histidine), aspartic acid (aspartic acid), arginine (arginine), threonine (threonine), glutamic acid (glutamic acid), proline (proline), cystine (cystine), methionine (methionine), isoleucine (isoluteine), leucine (leucine), tyrosine (tyrosine), phenylalanine (phenylalanine), and the like. Enters heart, liver, spleen and stomach meridians. Has the effects of clearing heat, cooling blood and detoxifying. It is commonly used for fever headache, high fever coma, macula, hematemesis and epistaxis, infantile convulsion, pharyngitis and swollen throat.
Lingyang jiao is a commonly used Chinese herb, listed as a Chinese herb in Shen nong Ben Cao Jing. The current commercial animal source is Saiga tatarica L-Vertebrata, Mammalia, Amidodactyla, Bovidae, Vertebrata, Proteus, Saiga Tatarici, and Mammalia. The alias of gao bi Ling yang. The cornu saigae tataricae contains 17 amino acids such as keratin calcium phosphate, insoluble inorganic salts, lysine (lysine), serine (serine), glutamic acid (glutamic acid), phenylalanine (phenylalanine), leucine (leucin), aspartic acid (aspartic acid), tyrosine (tyrosine), and five phospholipid components such as lecithin (lecithine), cephalin (cephalin), sphingomyelin (sphingomyelin), phosphatidylserine (phosphatidylserine), and phosphatidylinositol (phosphatidylsitose). Contains calcium phosphate, keratin and insoluble inorganic salt, wherein the content of keratin is the most. The keratin of antelope's horn contains only 1.2% of sulfur, and is one of the least sulfur in keratin. The modern research shows that the pharmacological effects are as follows: 1. effects on the central nervous system: the cornu Saigae Tataricae extract can reduce mouse directional motor reaction, inhibit central nervous system, accelerate barbital and ether anesthesia, and remarkably reduce sensitivity to pentamethylene tetrazole, strychnine and electroshock, but not cause muscle relaxation. The antelope horn decoction of 10g/kg is administrated by drenching mice, and can significantly reduce the convulsion rate caused by caffeine and accelerate the recovery rate, so that the death rate is reduced. The sleep time of the thiopentan sodium can be prolonged by injecting 10g/kg of antelope horn alcohol extract, 2g/kg of water decoction and 80mg/kg of hydrolysate into the abdominal cavity of a mouse. The antelope horn injection is injected into the abdominal cavity of the mouse at 80mg/kg, and the sleep time of the pentobarbital sodium can also be prolonged. 2. The antipyretic effect is as follows: the antelope horn decoction has antipyretic effect on the rabbits with fever caused by typhoid fever and paratyphoid hepatitis A and B triple vaccine, and the body temperature begins to decrease after 2 hours after the lavage and gradually recovers after 6 hours. 3. The function of reducing blood pressure: the blood pressure can be reduced by intravenous injection of cornu Saigae Tataricae ethanol extract 1g/kg into anesthetized dog or cat. The antelope horn preparation is applied to conscious rats at a concentration of 1g/kg, and has obvious blood pressure lowering effect. 4. Other functions are as follows: the antelope horn enzyme and the acid hydrolysis liquid have different degrees of inhibition effects on staphylococcus aureus, pseudomonas aeruginosa, influenza bacillus, streptococcus B and influenza virus. The cornu Saigae Tataricae skin leachate can increase animal tolerance to anoxia, and has analgesic effect.
Deer horn, british name "deeerhorn, Antler" latin name sika deer cervus nippon temminck or red deer c.elaphus l, wild white deer cervus maoneillydekker, white lip c.albirossprzewalski, red deer c.unicolor kerr. Chemical components: antler contains 25% of colloid, 50% -60% of calcium phosphate, calcium carbonate and nitride. Further amino acids include aspartic acid (aspartic acid), threonine (threonine), serine (serine), glutamic acid (glutamic acid), proline (proline), glycine (glycine), alanine (alanine), valine (valine), leucine (leucine), isoleucine (isoluteine), phenylalanine (phenylalanine), lysine (lysine), histidine (histidine), arginine (arginine). The pharmacological action is as follows: anti-inflammatory effects; when the n-Butanol Extract (BETA) of cornu Cervi Degelatinatum (Deerhorn antler) was administered to rat by intraperitoneal injection at a concentration of 50mg/kg, it was found that the mitochondrial monoamine oxidase (MAO) activity was significantly inhibited in liver and brain tissues of rat. In vitro experiments also demonstrated MAO inhibitory activity. 40mg/kg of antler extract can obviously increase the heart stroke amount of the halothane under light anesthesia.
The oxhorn mainly comprises oxhorn, Latin, Bostaurus domesticus Gmelin, and comprises the following main chemical components: sterols; amino acids: alanine, arginine, aspartic acid, cystine, leucine, proline, tyrosine, histidine, valine; peptides: hydrolysis of basic peptides, both of which produce arginine, lysine, histidine, glycine, alanine, proline, valine, leucine, and the like; a guanidino derivative; a protein. The properties and tastes of the herbs are bitter, salty and cold. The heart, liver and stomach meridians. The main indications are hematemesis, epistaxis, carbuncle, sore and furuncle and swelling caused by recklessly blood flow due to blood heat.
When the tender horn of pilose antler or male deer does not grow into hard bone, it is hairy and contains blood. Is a valuable Chinese medicine, can be used as tonic, and has therapeutic effect on asthenia and neurasthenia. The original animals are different and are divided into two types, namely spotted deer antler (hairy antler) and hairy deer antler (hairy antler); the harvesting method is different and is divided into two types of chopped antler and sawed antler; because the branches are different in size and tenderness, they can be divided into saddles, two bars, horns, three branches, flowers, chopped antler, lotus flowers and so on. (nature and taste) sweet, salty and warm. The meridian tropism is ascribed to kidney and liver meridians. [ function ] invigorating kidney yang, nourishing marrow and essence, strengthening tendons and bones, regulating Chong and ren meridians, and relieving sore toxin. The Chinese medicine composition is mainly used for treating kidney deficiency, dizziness, deafness, dim eyesight, impotence, spermatorrhea, infertility due to cold womb, emaciation, mental fatigue, intolerance of cold, cold pain in waist and back, bones and muscles atrophy, metrorrhagia, leukorrhagia, kidney-yang disunion, deficiency and damage due to long-term illness and the like.
Among the above animal horns, buffalo horn concentrated powder is a commercially available product, pilose antler can be used by a conventional method, and antelope horn, deer horn and ox horn are prepared by a new processing method. A preferred method of processing is described below: soaking in 75% ethanol or steam sterilizing, and pulverizing into fine powder. Adding 10 times of water by weight, decocting for two times, each time for 7-10 hours, supplementing distilled water at any time in the decocting process, mixing the decoctions, filtering, concentrating the filtrate to 1-5% of the original weight, drying at the temperature of below 80 ℃, crushing into fine powder, and sieving to obtain the traditional Chinese medicine composition. Mixing with other raw materials, and making into pill, powder, unguent or capsule.
The substitution standard of the raw material medicaments is as follows: compared with the first embodiment, the lower limit values of the effective rate and the cure rate are reduced by less than 2 percentage points, and the upper limit values are not limited. The following four combinations all meet the criteria for substitution.
1. 8-12 parts of buffalo horn concentrated powder, 1-3 parts of antelope horn and 8-12 parts of pilose antler.
2. 8-12 parts of buffalo horn concentrated powder, 1-3 parts of antelope horn and 8-12 parts of antler.
3. 8-12 parts of buffalo horn concentrated powder, 1-3 parts of antelope horn, 8-12 parts of antler and 8-12 parts of pilose antler.
4. 18-22 parts of ox horn powder, 1-3 parts of antelope horn and 8-12 parts of pilose antler.
Experiments prove that the third combination effect is the best, the first combination effect is the second, but the cost is lower, and the comprehensive effect is better. The second combination has a lower than the other two groups in term of efficacy, but the lowest cost and still has clinical significance. And the fourth method replaces buffalo horn with ox horn, the equivalent effect is slightly reduced, but the medicine source is sufficient, the cost is low, and the dosage can be increased, thereby having feasibility.
Third embodiment:
in addition to the second embodiment, 1-3 parts of sandalwood oil are replaced by 8-12 parts of white sandalwood and 8-12 parts of sandalwood.
The lignum Santali albi is dried wooden heartwood of Santalumalbuml. Contains volatile oil containing more than 90% of alpha-santalenol and beta-santalenol. It is pungent and warm in property and flavor when used as a medicine. Enter lung, stomach and spleen meridians. Has the effects of regulating qi, relieving chest stuffiness, dispelling cold, relieving pain, dispersing qi stagnation, relieving diaphragm stuffiness, relieving chest stuffiness, warming stomach and dispelling cold. It is indicated for chest and abdomen pain, dysphagia and vomiting. It can be used for treating febrile disease. For external application, it can relieve inflammation, relieve swelling, and condition skin. Delaying senility and is the main medicinal material for treating skin diseases in ancient times of China.
The pterocarpus santalinus contains volatile oil, and the main components of the volatile oil comprise alpha and beta-santalene (alpha-, beta-santalene), santalene (santene), santalene ketone (santenone), alpha-santalol (a-santenol), santalone (santal one), santaloic acid (santalinic acid), santaloic acid (teresantalic acid), santalol pigment (santalin), deoxysantalol pigment (deoxysantalin) and the like. Warm in nature and pungent in flavor. It enters spleen, stomach, heart and lung meridians. Move qi and warm middle energizer, stimulate appetite and alleviate pain. Can be used for treating qi stagnation due to cold accumulation, chest pain, abdominal pain, stomach pain, anorexia, coronary heart disease, and angina pectoris.
Pulverizing lignum Santali albi and lignum Pterocarpi Indici, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, paste or capsule.
Experiments prove that the white sandalwood and the purple sandalwood are used for replacing sandalwood oil, so that the dosage is increased, the effect influence is very little, the cost is greatly reduced, and the medicinal composition has certain practical value for primary hospitals.
The fourth embodiment:
on the basis of the third kind, 8-12 parts of clove oil are substituted.
Syzygium aromaticum (L.) Merr. EtPerry is the bud of caryophylli flos of Myrtaceae. The bud contains volatile oil, i.e. oleum Caryophylli. The oil mainly contains Eugenol (Eugenil), acetosyringol, B-Caryophyllene (B-Caryophyllene), methyl n-amyl ketone, methyl salicylate, humulene (Humulen), benzaldehyde, benzyl alcohol, m-methoxybenzaldehyde, benzyl acetate, piperonyl alcohol (Chavicol), a-Ylangene (a-Ylangene), etc. It can warm kidney and descend adverse qi. It is indicated for hiccup, vomiting, regurgitation, dysentery, psychroalgia, bubo, hernia, and tinea. The "sea medicine materia Medica" contains: mainly wind malnutrition, old and smelly bone groove. For qi deficiency, mustache onset, killing parasites, treating five hemorrhoids, disliking evil and eliminating evil. For premature ejaculation, it can stop five kinds of dysentery with toxic pathogen, and can treat heart and abdominal pain.
Pulverizing flos Caryophylli, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, ointment or capsule.
Experiments prove that the clove oil is replaced by clove, so that the dosage is increased, the drug effect influence is very little, the cost is greatly reduced, and the clove oil has a certain practical value for primary hospitals.
Fifth embodiment:
in the fourth embodiment, 8-12 parts of iris, 8-12 parts of blackberry lily, 8-12 parts of wild pueraria flower or 8-12 parts of iris japonica are used to replace tectoridin.
Iris, academic name: iris tectorum maxim, also known as: oroxylon indicum, and Phyllostachys Pubescens, belonging to order Asparagus, are the roots and stems of Iridaceae plant Iris. Contains tectoridin (tectoridin), tectoridin A, B (irisistorinA, B), tectoridin (tectoridine), etc. Pungent, bitter, cold and toxic. Has effects in promoting blood circulation, dispelling blood stasis, expelling pathogenic wind, removing dampness, removing toxic materials, and resolving food stagnation. It is commonly used for traumatic injury, rheumatic pain, sore throat, food retention, abdominal distention, malaria, pyogenic infections, hemorrhoids and fistula, and external application for treating carbuncle, furuncle, pyogenic infections and traumatic hemorrhage.
Belamcanda rhizome, another name: wu Fan, Wu Pu, Ye gan, Wu , Wu Chun, Cao Jiang, English name: blackberylily Rhizome, which is the Rhizome of Belamcanda chinensis of Iridaceae, contains isoflavone components: tectorigenin, Belamcandin, irisolidoidin, tectorigenin A, irisflorenin, irisorelin, 5-noririgenin, etc. Being bitter in flavor, cold, toxic, entering lung and liver meridians. Is a traditional Chinese medicine for clearing away heat and toxic materials, and has the functions of clearing away toxic materials and relieving sore throat, clearing lung heat to eliminate phlegm and salivation, and dissipating heat to eliminate stagnation. The main treatment is as follows: it is indicated for sore throat, cough, adverse rising of qi, excessive phlegm and saliva, scrofula, tuberculosis, malaria, amenorrhea, carbuncle, swelling and sore. The modern research shows that the blackberry lily has the effects of resisting pathogenic microorganisms, resisting inflammation, having estrogen-like effect, relieving fever, inhibiting the formation of gastric ulcer, benefiting gallbladder and resisting thrombus.
Pueraria lobata (Flos Pueraria) is flower of Pueraria lobata (Willd.) Ohwi) and Pueraria thomsonii Benth which are leguminous plants, and Pueraria thomsonii flower which is called as heterogenic Pueraria lobata flower has been used for relieving symptoms such as vomiting after drinking for a long time, the main effective component of the heterogenic Pueraria lobata flower is isoflavone compound, more than ten compounds are separated and identified at present and mainly exist in the form of glycoside, such as Pueraria flower glycoside, tectorigenin-7-O-xylopyranoside, tectoridin, genistein, formononetin and the like, and the isoflavone compounds have the effects of antioxidation, antibacterial activity and anticancer, and can prevent and treat osteoporosis, heart disease and the like.
Iris floribunda, which is the whole plant of Iridaceae plant Iris floribunda, contains isoflavone compounds such as irigenin A, B, irigenin glycoside A, B, tectorigenin, irigenin, 7-O-methyl vetiverin glycoside, Curculigenin methyl ether, irigenin methyl ether, juniperin B,5, 7-di-O-acetyl-6, 2 ', 3 ', 4 ', 5-pentamethoxyl isoflavone, and 5, 7-di-O-acetyl-6, 2 ', 3 ', 4-tetramethoxy isoflavone. The petals contain entibine and swertisin. The butterfly flower is sweet, bitter and neutral in taste, and can detoxify, relieve swelling and alleviate pain. It is used clinically to treat hepatitis, hepatomegaly, hepatalgia, laryngalgia, gastropathy, lumbar sprain, arthralgia, sore, furuncle, scabies, tinea, pruritus, etc.
Pulverizing rhizoma Iridis Tectori, rhizoma Belamcandae, flos Puerariae Lobatae, and flos Iridis Tectori, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, paste, or capsule.
The four plant medicines contain tectoridin, wherein iris, blackberry lily and iris are similar to those of iridaceae, the characters and the purposes are similar, and experiments show that the four plant medicines have similar effects on the lung diseases. Although the leguminous plant Pueraria lobata (flowers Pueraria) belongs to different genera, the recent research results show that the contained tectoridin component has strong activity, and experiments show that the extract can also replace tectoridin to achieve the treatment purpose.
Sixth embodiment:
in a fifth embodiment, 2 to 5 parts of calcium sulphate are replaced by 8 to 12 parts of gypsum.
Gypsum is a monoclinic mineral and has calcium sulfate (CaSO4) as the main chemical component. According to the relevant data, calcium sulfate is slightly soluble in water, but enters the stomach by oral administration, and under the action of gastric acid, a part of calcium sulfate is converted into calcium chloride and then becomes soluble calcium salt. In inorganic chemistry and organic chemistry, only calcium chloride salt and calcium nitrate salt are dissolved in water, and the substances dissolved in water are transported to various parts of the body along with the flow of blood to participate in the physiological functions of the body. When calcium ions in the organism meet with organic acids generated by organism metabolism or pathogenic microorganisms in the organism, the calcium ions are changed into insoluble calcium salts and lose toxicity. Particularly, metabolic acidosis occurs to patients with high fever, and the gypsum preparation has excellent performance: it not only neutralizes organic acid causing poisoning, but also acts with amino acid in pathogenic microorganism to make it lose nutrition and be inhibited. Although the gypsum is not an antibiotic, the gypsum plays a role in inhibiting the reproduction and development of pathogenic microorganisms by the antibiotic, is not antibiotic-like, has a broad spectrum of action, is effective to all pathogenic microorganisms, and does not generate drug resistance and has no side effect; although gypsum is not a fever reducing medicine, it can neutralize toxin to reduce fever of organism, playing a role of heat-clearing medicine; the calcium ion not only can maintain the normal function of nerves, but also can react with histamine generated by organism allergy to make it lose activity, and is anti-allergic. The calcium preparation also has effects of stopping bleeding, preventing body fluid exudation, and relieving inflammation, and can be used for treating burn.
This experiment demonstrates that replacing calcium sulfate with gypsum has a satisfactory effect.
The seventh embodiment:
on the basis of the sixth embodiment, 2 to 5 parts of dimethoxy coumarin is replaced by 8 to 12 parts of artemisia scoparia or 8 to 12 parts of oriental wormwood.
Artemisia scoparia, Artemisia scoparia Waldst et kit, Compositae Artemisia, perennial herbs of the genus Bismia, or nearly one or two year old herbs. The whole herb contains organic acids (citric acid, malic acid, acetic acid, propionic acid, valeric acid), rutin, quercetin-3-glucosyl galactoside, kaempferol-3-glucosyl galactoside, quercetin-3, 7-rutinosyl digalacoside, coumarin, isocoumarin, beta-sitosterol, bisabolol tannin, volatile oils (thujaol, n-butyraldehyde, furfural, methylheptone, carvone, 1,8-cineole, thujaponone, geranyl acetate, piperylene, eugenol, alpha-pinene, beta-pinene, agropylene, etc.), fatty oils (myristic acid, palmitic acid, stearic acid, arachidic acid, linoleic acid, oleic acid, etc.), 4-hydroxyacetophenone, choline, salicylic acid, etc., azelaic acid, caryophyllene epoxide, etc. The ash content of the whole grass contains elements such as silicon, lead, sodium, potassium, iron, magnesium, phosphorus, barium, strontium, silver, titanium, chromium, copper, aluminum, zinc, nickel, zirconium, gallium and the like. The seeds contain artesunide and coumarin. The leaves and flowers contain capillone, 1-phenyl 2, 4-hexadiyne-l-alcohol, and vanillin. Five flavones, 7-methyl-orange essence, rhamnoside, Eupatitin, Crisimeritin, Eupatitin, 7-methyl-horse chestnut bark essence, Scoparone and scopoletin are separated from inflorescence. The medicine is bitter and pungent in flavor and cool in nature. Clear lung heat, relieve cough and expel pus. It is indicated for cough due to lung heat, dyspnea, lung abscess, cold with cough, "beat heat" and swollen and sore throat.
Oriental Wormwood, english name Capillary Wormwood Herb, alias: artemisia alba, Artemisia argyi and herba Hyperici Japonici are aerial parts of Artemisia capillaris Thunb. Contains volatile oil, wherein the oil contains myrcene, limonene, eucalyptol, alpha-pinene, camphene, alpha-curcumene, davanone, capillone, eugenol, isoeugenol, naphthalene, benzaldehyde and borneol, and further contains capillin, 6, 7-dimethoxy coumarin and capillin A, B. Bitter and pungent in property and slightly cold in nature. It is entered into spleen, stomach, liver and gallbladder meridians. Has effects in clearing away heat, promoting diuresis, and eliminating jaundice. The main treatment is as follows: jaundice, dysuria, eczema, pruritus, infectious icterohepatitis, etc. Modern pharmacological studies prove that the oriental wormwood has the effects of benefiting gallbladder, promoting bile secretion, increasing the discharge of cholic acid and bilirubin in bile, increasing the blood flow of heart coronary artery, improving microcirculation, and has the effects of relieving fever, resisting inflammation, reducing blood pressure, reducing blood fat, resisting blood coagulation, promoting urination, relieving fever and asthma, expelling ascarid and inhibiting various pathogenic dermatophytes and bacteria. The artemisia capillaris decoction has a remarkable inhibition effect on the mutagenic action of AFB1, and is suggested to be significant for preventing liver cancer. The oriental wormwood has the functions of promoting the division of white blood cells, increasing the number of white blood cells, improving the immunocompetence of T cells, participating in the immune regulation of a body, inducing interferon and the like, thereby improving the immune function of the body from multiple aspects. Also has effects in resisting leptospira, killing ascaris, relieving asthma, and inhibiting and killing mouse ehrlich ascites carcinoma cells and MethA cells.
Pulverizing herba Artemisiae Scopariae and herba Artemisiae Scopariae, sieving with 60 mesh sieve, mixing with other materials, and making into pill, powder, ointment or capsule.
The artemisia scoparia and artemisia capillaris have similar characters and effects, so the artemisia scoparia and artemisia capillaris are considered as two raw materials of the Mongolian medicine artemisia capillaris. The experiment also proves that the two raw material medicines have equivalent effects on the treatment of the lung lesion and can replace the treatment effect of the dimethoxycoumarin.
The eighth embodiment:
in the seventh embodiment, 8-12 parts of myrobalan tannic acid is replaced by 8-12 parts of myrobalan.
Myrobalan, the name of traditional Chinese medicine. Dried ripe fruit of Terminalia chebula Retz. or Terminalia villosa Retz. var. tomatella Kurt. belonging to Combretaceae. Contains tannin 23.60-37.36%, and its components include Chebulagic acid (Chebulagic acid), Chebulagic acid (Chebulinic acid), procobalaminic acid (Terchebin), Corilagin (Corilagin), glucogallotannin (Glucogalin), gallic acid (Ellaggic acid), 1,3, 6-tri-galloylglucose and 1,2,3,4, 6-pentagalloylglucose, etc., shikimic acid, dehydroshikimic acid, quinic acid, arabinose, fructose, glucose, sucrose, rhamnose and amino acids, sennoside A, Chebulin, Tannase (Tannase), polyphenoloxidase (polyphenoloxidase), peroxidase and ascorbate oxidase, etc., and has astringent, antidiarrheal, spasmolytic, antiviral, anti-spasmodic, antiviral, antidiarrheal, lung-relieving cough, lung-relieving chronic diarrhea, chronic cough relieving asthma, chronic cough, chronic asthma, chronic cough, has good effects on sore throat, hoarseness and the like.
Pulverizing fructus Chebulae, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, unguent or capsule.
Experiments prove that: 8-12 parts of myrobalan are used for replacing 1-3 parts of myrobalan tannic acid, the treatment effect is very close, and the medicine is suitable for clinical application of basic-level personnel.
Ninth embodiment:
on the basis of the eighth embodiment, 1 to 3 parts of linaloe oil of the raw material medicine is replaced by 8 to 12 parts of agilawood, and 1 to 3 parts of carthamin is replaced by 8 to 12 parts of safflower.
Agilawood, english name Chinese Eaglewood, another name: agar, Aquilaria sinensis and Aquilaria sinensis, which are dicotyledonous plants, Aquilaria agallocha (Lour.) Roxb of arbor plant of Thymelaeaceae or Aquilaria sinensis A. sinensis (Lour.) Gilg, when the Aquilaria sinensis A. sinensis subjected to damage or artificial damage in the nature, the secreted oil is infected by fungi and is coagulated into secretion. The volatile oil of lignum Aquilariae Resinatum contains benzyl acetone, p-methoxy benzyl acetone, hydrogenated cinnamic acid, p-methoxy hydrogenated cinnamic acid, linalool (agar-spirol), linalool (agar), Agarofuran (Agarofuran), dihydroagarofuran, 4-hydroxy dihydroagarofuran, 3, 4-dihydroxy dihydroagarofuran C16H28O2, noragarofuran (Nor-ketoaga-rofuran), etc. Pungent, bitter and warm in nature. It is commonly indicated for dyspnea with dyspnea, vomiting, hiccup, abdominal pain, waist and knee deficiency cold, constipation due to deficiency of large intestine, stranguria due to urinary qi and cold sperm in man, and spleen, stomach, kidney and lung meridians entered. Treating wind-damp-toxicity swelling, removing malignant qi, and treating malignant tuberculosis swelling.
Safflower, a Chinese medicinal material known as Flos Carthami. Safflower is tubular corolla of Carthamus tinctorius L. Also called as Cao hong Hua, is warm in nature and pungent in flavor, and can activate blood and dredge meridians, dissipate blood stasis and alleviate pain. Can be used for treating coronary heart disease, traumatic injury, swelling and pain due to blood stasis, amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, swelling and pain due to pyocutaneous disease, and blood stasis due to hematemesis.
Pulverizing lignum Aquilariae Resinatum and Carthami flos, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, unguent or capsule.
Experiments prove that the medicine has good substitution effect and sufficient medicine sources, and is suitable for basic medical institutions and personnel.
Tenth embodiment:
based on the first or ninth embodiment, 8-12 parts of tsaoko amomum fruit, 8-12 parts of bistort rhizome, 8-12 parts of dwarf lilyturf tuber, 8-12 parts of hosta plantaginea flower and 8-12 parts of chicory.
Amomum tsaoko is the fruit of Amomum plant of Amomum of Zingiberaceae, named as fructus Tsaoko and fructus Tsaoko. The fruit contains volatile oil, the main components of the oil are alpha-pinene (alpha-pinene), beta-pinene (beta-pinene), 1,8-cineole (1,8-cineole), rho-cymene (rho-cymene), linalool (linalool), alpha-terpineol (alpha-terpineol), nerolidol (nerolidol), nonanal (nonanal), decanal (capric aldehyde), trans-2-undecenal (trans-2-undecenal, which is the pungent component in the product), neral (neral), geraniol (geraniol), and trace elements (mu g/g) of zinc 69.2, copper 7.33, iron 57.2, manganese 283.7 and cobalt 0.89. Pungent taste, warm nature and no toxicity. Enter spleen and stomach meridians. Has the functions of eliminating dampness and cold, eliminating phlegm and checking malaria, strengthening spleen and stimulating appetite, and inducing diuresis to alleviate edema. The main indications are malaria, phlegm and fluid retention and fullness, abdominal cold pain, regurgitation, vomiting, diarrhea and dysentery and food retention. The composition can be used for treating deficiency heat, cough, edema, dysuria, infantile heat convulsion, and sore and swelling of head.
Bistort rhizome, english: rhizoma Bistortae Latin name: polygonum biostarta L. [ p. lapidosum kitag. ] alternative: root and rhizome of Polygonum bistorta L. of Polygonaceae. Contains gallic acid (gallic acid), gallic acid (ellagic acid) and hydrolysable tannin and condensed tannin. It also contains D-catechol (catechol), L-epi-tea phenol (epicatechol), 6-galloylglucose (galloglucoside), and 3, 6-digallitol glucose (3, 6-digallate glucose (glucose)). And isomers of hydroxymethyl anthraquinone, vitamin 2, beta-sitosterol, etc. The whole herb contains chlorogenic acid (chloroenic acid), caffeic acid (caffeic acid), protocatechuic acid (protocatholic acid), hyperin (hyperin) and the like. Bitter in nature and cool. It enters lung, liver and large intestine meridians. Has effects in clearing away heat, relieving convulsion, and eliminating dampness and swelling. It is used to treat febrile convulsion, tetanus, dysentery, carbuncle, scrofula. Clearing heat and promoting diuresis; cooling blood to stop bleeding; detoxify and dissipate nodulation. Cough due to lung heat manifested as bistort cough; febrile convulsion; dysentery with bloody stool; hot purgation; hematemesis; bleeding; haemorrhoids bleeding; abscess, swelling and sore.
Ophiopogon japonicus, a cultivar of Ophiopogon japonica (Linn. f.) Ker-Gawl. Liliaceae, a perennial evergreen herb, and both types of Ophiopogon japonicus and Ophiopogon japonicus. Also called ophiopogon root, ophiopogon japonicus, Hangzhou ophiopogon root, Sichuan ophiopogon root, ophiopogon root and wheat ophiopogon root, contains various steroidal saponins, ophiopogonin A, B, C, D, the aglycone is ruscogenin, and the ophiopogonin B ', C ' and D ' are diosgenin; contains various flavonoid compounds: such as radix Ophiopogonis methyl flavanone A, B, radix Ophiopogonis flavanone A, radix Ophiopogonis flavone A, B, methyl radix Ophiopogonis flavone A, B; and 5 homoisoflavonoid compounds are obtained. Sweet, slightly bitter and slightly cold in nature and taste. It enters heart, lung and stomach meridians. Has the effects of nourishing yin, promoting the production of body fluid, moistening lung and clearing heart fire, and is mainly used for dry cough due to lung dryness, tuberculosis cough due to yin deficiency, sore throat, thirst due to body fluid consumption, internal heat, diabetes, vexation, insomnia and constipation due to intestinal dryness.
Hostaplantagineaarches, alternative name: the fragrant solomonseal rhizome, the hairyvein agrimony, the soaked flower of the fragrant solomonseal rhizome and the hosta plantaginea, which are medicinal herbs with sweet, cool and slightly toxic. Has effects in regulating qi, promoting blood circulation, tonifying deficiency, moistening lung, relieving cough, removing Mylabris toxin, stopping pregnancy, and relieving swelling. Can be used for treating swelling and pain of throat, urinary obstruction, sore, burn, spermatorrhea, hematemesis, emphysema, metrorrhagia, and leucorrhea.
Chicory peptide, latin name: lactuca sativa l. alias: semen Lactucae Sativae, semen Cichorii , semen Cichorii, and semen Lactucae Sativae, which are fruits of Lactuca sativa L. Pungent, bitter and slightly warm taste, enters stomach and liver meridians, has diuretic effect, and has effects of resisting arrhythmia, promoting lactation, promoting urination, promoting blood circulation and removing blood stasis, and can be used for treating galactostasis, dysuria, traumatic injury, swelling and pain, and swelling and pain of scrotum.
The added raw materials can be pulverized into powder, sieved with more than 60 meshes, mixed with other medicines, and made into various dosage forms such as pills, powder, ointment, capsules and the like. However, the dosage should be increased by more than 1g based on the first embodiment.
The raw materials are added to form various combinations, and only five typical experimental examples are listed below:
1. 12-18 parts of cuprammonium, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 1-3 parts of Chinese eaglewood oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of iritin, 16-24 parts of cardamom, 8-12 parts of radix glehniae, 8-12 parts of black clouds, 1-3 parts of myrobalan tannic acid, 8-12 parts of calculus bovis factitious, 1-2 parts of musk factitious, 8-12 parts of tsaoko amomum fruit, 8-12 parts of bistort rhizome, 8-12 parts of radix ophiopogonis, 8-12 parts of hosta plantaginea flower and 8-12 parts of victoria.
Wherein the cardamom, the radix glehniae, the black cloud incense, the tsaoko amomum fruit, the bistort rhizome, the dwarf lilyturf tuber, the hosta plantaginea flower and the chicory powder are screened by a sieve with more than 60 meshes and mixed with other raw material medicines.
The taking method comprises the following steps: the medicine is taken 2-3 times a day for 2-3 g/adult. One week is a treatment course.
The disease condition is relieved effectively, the symptom disappears, the relapse is not found in 3 months, the disease is cured, and the disease is not relieved after the medicine is taken for two weeks. The types, the number and the treatment conditions of the lung lesions are as follows:
disease species Number of examples Is effective Cure of disease Invalidation Effective rate (%) Cure rate (%)
Cough with profuse sputum 41 7 31 3 92.7 75.6
Abscess of chest and lung 36 6 26 4 88.9 72.2
Pulmonary tuberculosis 30 6 19 5 83.3 63.3
Lung cancer 22 14 5 3 86.4 22.7
Effective rate = (effective number + cured number)/total number X100%, and cure rate = cured number/total number X100%.
It can be seen that the therapeutic effect is superior to that of the first embodiment.
2. 12-18 parts of cuprum ash, 8-12 parts of concentrated ox horn powder, 8-12 parts of antelope horn, 8-12 parts of pilose antler, 8-12 parts of gypsum, 8-12 parts of white sandalwood, 8-12 parts of clove, 8-12 parts of agilawood, 8-12 parts of safflower, 8-12 parts of oriental wormwood, 8-12 parts of blackberry lily, 8-12 parts of cardamom, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of black clouds, 8-12 parts of myrobalan, 8-12 parts of artificial bezoar, 1-2 parts of artificial musk, 8-12 parts of tsaoko amomum fruit, 8-12 parts of bistort rhizome, 8-12 parts of dwarf lilyturf tuber, 8-12 parts of hosta plantain flower and 8-12 parts of witloof.
Wherein the cornu Saigae Tataricae is prepared by soaking in 75% ethanol or steam sterilizing, and pulverizing into fine powder. Adding 10 times of water, decocting for two times, each time for 7-10 hours, supplementing distilled water at any time in the decocting process, mixing the decoctions, filtering, concentrating the filtrate to 1-5% of the original weight, drying at the temperature of below 80 ℃, crushing into fine powder, and sieving with a sieve of more than 60 meshes to obtain the traditional Chinese medicine composition. Pulverizing fructus Amomi rotundus, radix Glehniae, HEIYUNXIANG, lignum Santali albi, flos Caryophylli, rhizoma Belamcandae, herba Artemisiae Scopariae, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hostae Plantagineae, and herba Cichorii, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, ointment or capsule.
The taking method comprises the following steps: 5-6 g for adult, and 2-3 times daily. A treatment course is 10 days.
The disease condition is relieved effectively after taking for one course of treatment, the symptom disappears, the disease is cured after 3 months, and the disease is not relieved after taking for two weeks. The types, the number and the treatment conditions of the lung lesions are as follows:
disease species Number of examples Is effective Cure of disease Invalidation High efficiency(%) Cure rate (%)
Cough with profuse sputum 41 8 28 5 87.8 68.3
Abscess of chest and lung 32 5 23 4 87.5 71.9
Pulmonary tuberculosis 32 4 19 9 71.9 59.4
Lung cancer 25 14 5 6 76.0 20.0
Effective rate = (effective number + cured number)/total number X100%, and cure rate = cured number/total number X100%.
It can be seen that the treatment effect is close to that of the first embodiment, the cost is lower although the dosage is larger, and the clinical application value is still higher.
3. 2-4 parts of verdigris, 8-12 parts of concentrated ox horn powder, 8-12 parts of antelope horn, 8-12 parts of pilose antler, 8-12 parts of gypsum, 8-12 parts of white sandalwood, 8-12 parts of clove, 8-12 parts of agilawood, 8-12 parts of safflower, 8-12 parts of artemisia scoparia, 8-12 parts of pueraria lobata, 8-12 parts of amomum cardamomum, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of black clouds, 8-12 parts of myrobalan, 8-12 parts of artificial bezoar, 1-2 parts of artificial musk, 8-12 parts of tsaoko amomum fruits, 8-12 parts of bistort rhizome, 8-12 parts of dwarf lilyturf tuber, 8-12 parts of hosta plantain flower and 8-12 parts of witloof.
Wherein the cornu bovis Seu Bubali and cornu Saigae Tataricae are prepared by soaking in 75% ethanol or steam sterilizing, and pulverizing into fine powder. Adding 10 times of water, decocting for two times, each time for 7-10 hours, supplementing distilled water at any time in the decocting process, mixing the decoctions, filtering, concentrating the filtrate to 1-5% of the original weight, drying at the temperature of below 80 ℃, crushing into fine powder, and sieving with a sieve of more than 60 meshes to obtain the traditional Chinese medicine composition. Pulverizing fructus Amomi rotundus, radix Glehniae, HEIYUNXIANG, lignum Santali albi, lignum Pterocarpi Indici, flos Artemisiae Anomalae, flos Puerariae Lobatae, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hostae Plantagineae, and herba Cichorii, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, paste or capsule.
The taking method comprises the following steps: 5-6 g for adult, and 2-3 times daily. A treatment course is 10 days.
The disease condition is relieved effectively after one course of administration, the symptom disappears, and no relapse occurs after 3 months of follow-up visit to be cured, and the disease condition is not relieved after two courses of administration to be ineffective. The types, the number and the treatment conditions of the lung lesions are as follows:
disease species Number of examples Is effective Cure of disease Invalidation Effective rate (%) Cure rate (%)
Cough with profuse sputum 43 7 30 6 86.0 69.8
Abscess of chest and lung 35 5 25 5 85.7 71.4
Pulmonary tuberculosis 33 4 20 9 72.7 60.6
Lung cancer 27 14 6 7 74.1 22.2
Effective rate = (effective number + cured number)/total number X100%, and cure rate = cured number/total number X100%.
It can be seen that the treatment effect is close to that of the first embodiment, the cost is lower although the dosage is larger, and the clinical application value is still higher.
4. 2-3 parts of Chalcanthitum, 18-22 parts of ox horn, 8-12 parts of antelope horn, 8-12 parts of pilose antler, 8-12 parts of gypsum, 8-12 parts of white sandalwood, 8-12 parts of clove, 8-12 parts of agilawood, 8-12 parts of safflower, 8-12 parts of artemisia argyi, 8-12 parts of butterfly flower, 8-12 parts of cardamom, 8-12 parts of nutmeg, 8-12 parts of radix glehniae, 8-12 parts of black clouds, 8-12 parts of myrobalan, 8-12 parts of artificial bezoar, 1-2 parts of artificial musk, 8-12 parts of tsaoko amomum fruit, 8-12 parts of bistort rhizome, 8-12 parts of dwarf lilyturf tuber, 8-12 parts of hosta flower and 8-12 parts of Cichorium chinensis.
Wherein the cornu bovis Seu Bubali and cornu Saigae Tataricae are prepared by soaking in 75% ethanol or steam sterilizing, and pulverizing into fine powder. Adding 10 times of water, decocting for two times, each time for 7-10 hours, supplementing distilled water at any time in the decocting process, mixing the decoctions, filtering, concentrating the filtrate to 1-5% of the original weight, drying at the temperature of below 80 ℃, crushing into fine powder, and sieving with a sieve of more than 60 meshes to obtain the traditional Chinese medicine composition. Pulverizing fructus Amomi rotundus, radix Glehniae, HEIYUNXIANG, lignum Santali albi, flos Caryophylli, herba Artemisiae Scopariae, flos Oroxyli, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hostae Plantagineae, and herba Cichorii, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, paste or capsule.
The taking method comprises the following steps: 5-6 g for adult, and 2-3 times daily. A treatment course is 10 days.
The disease condition is relieved effectively after one course of administration, the symptom disappears, and no relapse occurs after 3 months of follow-up visit to be cured, and the disease condition is not relieved after two courses of administration to be ineffective. The types, the number and the treatment conditions of the lung lesions are as follows:
disease species Number of examples Is effective Cure of disease Invalidation Effective rate (%) Cure rate (%)
Cough with profuse sputum 44 7 31 6 86.4 70.5
Abscess of chest and lung 37 5 26 6 83.8 70.3
Pulmonary tuberculosis 36 4 22 10 72.2 61.1
Lung cancer 24 13 5 6 75.0 20.8
Effective rate = (effective number + cured number)/total number X100%, and cure rate = cured number/total number X100%.
It can be seen that the treatment effect is close to that of the first embodiment, the cost is lower although the dosage is larger, and the clinical application value is still higher.
5. The preparation method comprises pulverizing fructus Amomi rotundus, radix Glehniae, herba Blumeae Laciniatae, lignum Santali albi, flos Caryophylli, rhizoma Iridis Tectori, rhizoma Belamcandae, flos Puerariae Lobatae, flos Iridis Tectori, herba Artemisiae Scopariae, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hosta plantaginea, and herba Cichorii, sieving with 80 mesh sieve, mixing, extracting with 70% ethanol for 30-60 min, and recovering ethanol under reduced pressure; extracting with ethyl acetate for 30-60 min, recovering solvent, concentrating, pulverizing, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, ointment or capsule.
Compared with the current general mode that the alcohol extract is sequentially eluted by different solvents, the process adopts the mode of solvent soaking without extraction, and has three advantages: firstly, the steps of solvent extraction are reduced; secondly, the extracted components are in situ and are still convenient for the patient to absorb and utilize; thirdly, the quality requirement of extraction is not high, and the effective components which are not dissolved out can still be reserved and utilized. The taking method comprises the following steps: the medicine is taken 2-3 times a day for 2-3 g/adult. One week is a treatment course.
The medicine adopting the process has the effect time close to that of the first embodiment, and the treatment effect is obviously better than that of the experimental examples. The formulas of the 2 nd, 3 rd and 4 th experimental examples are respectively processed by the process, and the average values are obtained after the respective experiments, and the results are as follows:
the taking method comprises the following steps: the medicine is taken 3-4 g/time for an adult, 2-3 times a day, and 7 days is a course of treatment.
The disease is relieved effectively after being taken for one week, the symptom disappears, and the disease is cured after being visited for 3 months, and the disease is not relieved effectively after being taken for two weeks. The types, the number and the treatment conditions of the lung lesions are as follows:
disease species Number of examples Is effective Cure of disease Invalidation Effective rate (%) Cure rate (%)
Cough with profuse sputum 43 7 32 4 90.7 74.4
Abscess of chest and lung 40 6 29 5 87.5 72.5
Pulmonary tuberculosis 31 6 20 5 83.9 64.5
Lung cancer 24 14 6 4 83.3 25.0
Effective rate = (effective number + cured number)/total number X100%, and cure rate = cured number/total number X100%.
Therefore, by adopting the new processing technology, the taking dosage is reduced compared with the experimental examples 2,3 and 4, the taking is more convenient, and the treatment effect is enhanced.

Claims (9)

1. A Mongolian medicine for treating chest lung abscess and phthisis is characterized in that: the Mongolian medicine is prepared from the following raw material medicines in parts by weight: 12-18 parts of prepared copper ash or 2-4 parts of verdigris or 2-3 parts of blue vitriol, 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate, 2-5 parts of hydrous calcium sulfate, 2-5 parts of amino acid, 1-3 parts of sandalwood oil, 1-3 parts of clove oil, 1-3 parts of Chinese eaglewood oil, 1-3 parts of carthamin, 2-5 parts of dimethoxycoumarin, 0.5-1 part of tectoridin, 1-3 parts of myrobalan tannic acid, 16-24 parts of cardamon, 8-12 parts of radix glehniae, 8-12 parts of black musk, 8-12 parts of calculus bovis factitius and 1-2 parts of artificial musk.
2. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 1, which is characterized in that: 2-5 parts of calcium carbonate, 2-5 parts of calcium phosphate and 2-5 parts of amino acid are replaced by 40-60 parts of cloven-hoof animal horn.
3. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 2, which is characterized in that: the 40-60 parts of the clover hoof animal horn are prepared from 8-12 parts of buffalo horn concentrated powder, 8-12 parts of antelope horn, 8-12 parts of antler, 18-22 parts of ox horn and 8-12 parts of pilose antler.
4. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 1, which is characterized in that: the cardamom 16-24 parts are cardamom 8-12 parts and nutmeg 8-12 parts.
5. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 1, which is characterized in that: the raw material medicines of sandalwood oil, clove oil, linaloe oil, carthamin, dimethoxycoumarin, tectoridin and myrobalan tannic acid are respectively replaced by the following raw material medicines: the sandalwood oil is replaced by 8-12 parts of white sandalwood and 8-12 parts of purple sandalwood; the clove oil is replaced by 8-12 parts of clove; the tectoridin is replaced by 8-12 parts of iris, 8-12 parts of blackberry lily, 8-12 parts of kudzu vine flower or 8-12 parts of iris japonica; 8-12 parts of gypsum are used for replacing the calcium sulfate; 8-12 parts of artemisia scoparia or 8-12 parts of oriental wormwood are used for replacing the dimethoxycoumarin; the myrobalan tannic acid is replaced by 8-12 parts of myrobalan; 8-12 parts of agilawood is used for replacing the linaloe oil; the carthamin is replaced by 8-12 parts of safflower.
6. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 5, which is characterized in that: the raw material medicines comprise 8-12 parts of tsaoko amomum fruits, 8-12 parts of bistort rhizome, 8-12 parts of radix ophiopogonis, 8-12 parts of hosta plantaginea flowers and 8-12 parts of cichorium victorioides.
7. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 3, which is characterized in that: the processing method of cornu Saigae Tataricae, cornu Cervi, and cornu bovis Seu Bubali comprises soaking in 75% ethanol or steam sterilizing, and pulverizing into fine powder; adding 10 times of water by weight, decocting for two times, each time for 7-10 hours, supplementing distilled water at any time in the decocting process, mixing decoctions, filtering, concentrating the filtrate to 1-5% of the original weight, drying at the temperature of below 80 ℃, pulverizing into fine powder, and sieving to obtain the traditional Chinese medicine composition; mixing with other raw materials, and making into pill, powder, unguent or capsule.
8. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 6, which is characterized in that: the manufacturing process of the Mongolian medicine comprises the following steps: pulverizing fructus Amomi rotundus, radix Glehniae, HEIYUNXIANG, lignum Santali albi, lignum Pterocarpi Indici, flos Caryophylli, rhizoma Iridis Tectori, rhizoma Belamcandae, flos Puerariae Lobatae, flos Oroxyli, herba Artemisiae Scopariae, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hostae Plantagineae, and BAICAOSHEN, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, paste or capsule.
9. The Mongolian medicine for treating chest lung abscess and tuberculosis as claimed in claim 6, which is characterized in that: the manufacturing process of the Mongolian medicine comprises the following steps: pulverizing fructus Amomi rotundus, radix Glehniae, HEIYUNXIANG, lignum Santali albi, lignum Pterocarpi Indici, flos Caryophylli, rhizoma Iridis Tectori, rhizoma Belamcandae, flos Puerariae Lobatae, flos Oroxyli, herba Artemisiae Scopariae, fructus Chebulae, lignum Aquilariae Resinatum, Carthami flos, fructus Tsaoko, rhizoma Bistortae, radix Ophiopogonis, flos Hostae Plantagineae, and herba Cichorii, sieving with 80 mesh sieve, mixing, extracting with 70% ethanol for 30-60 min, and recovering ethanol under reduced pressure; extracting with ethyl acetate for 30-60 min, recovering solvent, concentrating, pulverizing, sieving with 60 mesh sieve, mixing with other raw materials, and making into pill, powder, ointment or capsule.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005107734A1 (en) * 2004-05-06 2005-11-17 Taiyokagaku Co., Ltd. Alcohol metabolism accelerating composition, and food or drink containing the composition
CN107582899A (en) * 2017-10-21 2018-01-16 内蒙古民族大学附属医院 The anaesthetic and its manufacturing process of a kind of clearing away heat to stop bleeding

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005107734A1 (en) * 2004-05-06 2005-11-17 Taiyokagaku Co., Ltd. Alcohol metabolism accelerating composition, and food or drink containing the composition
CN107582899A (en) * 2017-10-21 2018-01-16 内蒙古民族大学附属医院 The anaesthetic and its manufacturing process of a kind of clearing away heat to stop bleeding

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"三十五味沉香丸分别有什么成分";康爱多网上药店;《https://www.360kad.com/medication/2532048.shtml》;20160407;第1-3页 *
四味沙参汤治疗小儿迁延性肺炎体会;楚伦巴特尔;《中国民族医药杂志》;19961231;第2卷(第2期);第19页 *

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